Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	podosome	DOCK5 SH3PXD2A CD2AP ADAM8	3.48e-06	41	53	4	GO:0002102
GeneOntologyCellularComponent	MLL1 complex	KMT2A HCFC2 MEN1	7.25e-05	32	53	3	GO:0071339
GeneOntologyCellularComponent	MLL1/2 complex	KMT2A HCFC2 MEN1	7.96e-05	33	53	3	GO:0044665
GeneOntologyCellularComponent	actin cytoskeleton	DOCK5 MYLK SH3PXD2A CD2AP BAG3 LMOD1 ARHGAP35 ADAM8	9.41e-05	576	53	8	GO:0015629
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class I	PIK3R2 PIK3R3	2.24e-04	9	53	2	GO:0097651
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class IA	PIK3R2 PIK3R3	2.24e-04	9	53	2	GO:0005943
GeneOntologyCellularComponent	anchoring junction	DOCK5 MYLK SH3PXD2A ADAM15 PIK3R2 CD2AP NECTIN2 TJP2 ARHGAP17	7.07e-04	976	53	9	GO:0070161
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2A HCFC2 MEN1	9.13e-04	75	53	3	GO:0035097
Domain	SH3	DOCK5 PRAM1 MYO15B SH3PXD2A PIK3R2 CD2AP TJP2	2.46e-06	216	53	7	SM00326
Domain	SH3	DOCK5 PRAM1 MYO15B SH3PXD2A PIK3R2 CD2AP TJP2	2.46e-06	216	53	7	PS50002
Domain	SH3_domain	DOCK5 PRAM1 MYO15B SH3PXD2A PIK3R2 CD2AP TJP2	2.78e-06	220	53	7	IPR001452
Domain	PI3K_P85_iSH2	PIK3R2 PIK3R3	2.37e-05	3	53	2	IPR032498
Domain	PI3K_P85_iSH2	PIK3R2 PIK3R3	2.37e-05	3	53	2	PF16454
Domain	HMG14_17	HMGN4 HMGN3	7.86e-05	5	53	2	PS00355
Domain	HMG17	HMGN4 HMGN3	7.86e-05	5	53	2	SM00527
Domain	PI3kinase_P85	PIK3R2 PIK3R3	7.86e-05	5	53	2	IPR001720
Domain	SAPAP	DLGAP1 DLGAP4	7.86e-05	5	53	2	IPR005026
Domain	GKAP	DLGAP1 DLGAP4	7.86e-05	5	53	2	PF03359
Domain	HMG14_17	HMGN4 HMGN3	7.86e-05	5	53	2	PF01101
Domain	HMGN_fam	HMGN4 HMGN3	7.86e-05	5	53	2	IPR000079
Domain	RhoGAP	PIK3R2 ARHGAP17 ARHGAP35	7.25e-04	62	53	3	SM00324
Domain	RhoGAP	PIK3R2 ARHGAP17 ARHGAP35	7.60e-04	63	53	3	PF00620
Domain	RHOGAP	PIK3R2 ARHGAP17 ARHGAP35	7.96e-04	64	53	3	PS50238
Domain	RhoGAP_dom	PIK3R2 ARHGAP17 ARHGAP35	7.96e-04	64	53	3	IPR000198
Domain	-	PIK3R2 ARHGAP17 ARHGAP35	7.96e-04	64	53	3	1.10.555.10
Domain	ADAM_CR	ADAM15 ADAM8	1.17e-03	18	53	2	PF08516
Domain	SH3_1	DOCK5 SH3PXD2A PIK3R2 CD2AP	1.20e-03	164	53	4	PF00018
Domain	-	ADAM15 ADAM8	1.45e-03	20	53	2	4.10.70.10
Domain	Disintegrin	ADAM15 ADAM8	1.60e-03	21	53	2	PF00200
Domain	DISIN	ADAM15 ADAM8	1.60e-03	21	53	2	SM00050
Domain	SH3_2	MYO15B CD2AP TJP2	1.87e-03	86	53	3	IPR011511
Domain	SH3_2	MYO15B CD2AP TJP2	1.87e-03	86	53	3	PF07653
Domain	Rho_GTPase_activation_prot	PIK3R2 ARHGAP17 ARHGAP35	2.00e-03	88	53	3	IPR008936
Domain	ACR	ADAM15 ADAM8	2.65e-03	27	53	2	SM00608
Domain	ADAM_Cys-rich	ADAM15 ADAM8	2.65e-03	27	53	2	IPR006586
Domain	Peptidase_M12B_N	ADAM15 ADAM8	5.47e-03	39	53	2	IPR002870
Domain	Pep_M12B_propep	ADAM15 ADAM8	5.47e-03	39	53	2	PF01562
Domain	DISINTEGRIN_1	ADAM15 ADAM8	5.75e-03	40	53	2	PS00427
Domain	Reprolysin	ADAM15 ADAM8	5.75e-03	40	53	2	PF01421
Domain	ADAM_MEPRO	ADAM15 ADAM8	5.75e-03	40	53	2	PS50215
Domain	DISINTEGRIN_2	ADAM15 ADAM8	5.75e-03	40	53	2	PS50214
Domain	Peptidase_M12B	ADAM15 ADAM8	5.75e-03	40	53	2	IPR001590
Domain	Disintegrin_dom	ADAM15 ADAM8	6.04e-03	41	53	2	IPR001762
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK5 SRRM1 SH3PXD2A PIK3R2 PIK3R3 TJP2 ARHGAP17 ARHGAP35 FMNL1	5.55e-06	450	42	9	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK5 SRRM1 MYLK SH3PXD2A PIK3R2 PIK3R3 TJP2 ARHGAP17 ARHGAP35 FMNL1 MEN1	5.72e-06	720	42	11	M41838
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK5 PIK3R2 PIK3R3 ARHGAP17 ARHGAP35 FMNL1	1.22e-05	175	42	6	MM15599
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK5 SRRM1 MYLK PIK3R2 PIK3R3 TJP2 ARHGAP17 ARHGAP35 FMNL1 MEN1	1.54e-05	649	42	10	MM15690
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK5 PIK3R2 PIK3R3 ARHGAP17 ARHGAP35 FMNL1	1.62e-05	184	42	6	M41809
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK5 SRRM1 PIK3R2 PIK3R3 TJP2 ARHGAP17 ARHGAP35 FMNL1	3.86e-05	439	42	8	MM15595
Pathway	REACTOME_CDC42_GTPASE_CYCLE	SH3PXD2A PIK3R2 ARHGAP17 ARHGAP35 FMNL1	9.23e-05	155	42	5	M41808
Pathway	PID_NEPHRIN_NEPH1_PATHWAY	PIK3R2 CD2AP PIK3R3	1.04e-04	31	42	3	M193
Pathway	WP_PI3KAKTMTOR_SIGNALING_AND_THERAPEUTIC_OPPORTUNITIES_IN_PROSTATE_CANCER	PIK3R2 PIK3R3 FOXO4	1.15e-04	32	42	3	M39445
Pathway	REACTOME_RAC2_GTPASE_CYCLE	PIK3R2 PIK3R3 ARHGAP17 ARHGAP35	1.27e-04	87	42	4	MM15600
Pathway	REACTOME_RAC2_GTPASE_CYCLE	PIK3R2 PIK3R3 ARHGAP17 ARHGAP35	1.32e-04	88	42	4	M41810
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2A HCFC2 MEN1	1.93e-04	38	42	3	MM17073
Pathway	REACTOME_RET_SIGNALING	PIK3R2 PIK3R3 MAPK7	1.93e-04	38	42	3	MM15493
Pathway	WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY	MYLK PIK3R2 PIK3R3 MAPK7	2.09e-04	99	42	4	MM15905
Pathway	REACTOME_RET_SIGNALING	PIK3R2 PIK3R3 MAPK7	2.25e-04	40	42	3	M27746
Pathway	WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY	MYLK PIK3R2 PIK3R3 MAPK7	2.52e-04	104	42	4	M39625
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2A HCFC2 MEN1	2.60e-04	42	42	3	M48018
Pathway	KEGG_MEDICUS_REFERENCE_PDL_PD1_SHP_PI3K_SIGNALING_PATHWAY	PIK3R2 PIK3R3	3.08e-04	9	42	2	M47757
Pathway	KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY	PIK3R2 PIK3R3	3.08e-04	9	42	2	M47972
Pathway	REACTOME_RHOD_GTPASE_CYCLE	PIK3R2 ARHGAP17 ARHGAP35	5.19e-04	53	42	3	M41811
Pathway	WP_CANCER_IMMUNOTHERAPY_BY_CTLA4_BLOCKADE	PIK3R2 PIK3R3	7.71e-04	14	42	2	M39840
Pathway	KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY	PIK3R2 PIK3R3	8.88e-04	15	42	2	M47971
Pathway	REACTOME_INTERLEUKIN_7_SIGNALING	PIK3R2 PIK3R3	8.88e-04	15	42	2	MM14536
Pathway	REACTOME_RHOD_GTPASE_CYCLE	PIK3R2 ARHGAP17 ARHGAP35	9.03e-04	64	42	3	MM15601
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	MYLK PIK3R2 PIK3R3 ARHGAP35	1.01e-03	150	42	4	M39520
Pathway	WP_AIRWAY_SMOOTH_MUSCLE_CELL_CONTRACTION	MYLK RYR1	1.01e-03	16	42	2	M40060
Pathway	REACTOME_RHOJ_GTPASE_CYCLE	PIK3R2 ARHGAP35	1.01e-03	16	42	2	MM15605
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	SEMA6D PIK3R2 PIK3R3 ARHGAP35 MAPK7	1.02e-03	261	42	5	MM15676
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	MYLK PIK3R2 PIK3R3 ARHGAP35	1.06e-03	152	42	4	MM15834
Pathway	REACTOME_RHOB_GTPASE_CYCLE	PIK3R2 TJP2 ARHGAP35	1.12e-03	69	42	3	MM15596
Pathway	WP_NONALCOHOLIC_FATTY_LIVER_DISEASE	PIK3R2 PIK3R3 MLXIP NDUFV3	1.14e-03	155	42	4	M39806
Pathway	REACTOME_RHOB_GTPASE_CYCLE	PIK3R2 TJP2 ARHGAP35	1.17e-03	70	42	3	M41806
Pathway	REACTOME_SIGNALING_BY_KIT_IN_DISEASE	PIK3R2 PIK3R3	1.59e-03	20	42	2	M39002
Pathway	REACTOME_REGULATION_OF_SIGNALING_BY_CBL	PIK3R2 PIK3R3	1.76e-03	21	42	2	MM15633
Pathway	REACTOME_REGULATION_OF_SIGNALING_BY_CBL	PIK3R2 PIK3R3	1.93e-03	22	42	2	M903
Pathway	REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	PIK3R2 PIK3R3	1.93e-03	22	42	2	M13897
Pathway	REACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING	PIK3R2 PIK3R3	1.93e-03	22	42	2	MM15632
Pathway	REACTOME_NEPHRIN_FAMILY_INTERACTIONS	PIK3R2 CD2AP	2.11e-03	23	42	2	M913
Pathway	REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	PIK3R2 PIK3R3	2.11e-03	23	42	2	MM14993
Pathway	WP_4HYDROXYTAMOXIFEN_DEXAMETHASONE_AND_RETINOIC_ACIDS_REGULATION_OF_P27_EXPRESSION	PIK3R2 PIK3R3	2.49e-03	25	42	2	M39574
Pathway	PID_INTEGRIN_A9B1_PATHWAY	ADAM15 ADAM8	2.49e-03	25	42	2	M118
Pathway	REACTOME_RAC3_GTPASE_CYCLE	PIK3R2 ARHGAP17 ARHGAP35	2.65e-03	93	42	3	MM15609
Pathway	REACTOME_RAC3_GTPASE_CYCLE	PIK3R2 ARHGAP17 ARHGAP35	2.73e-03	94	42	3	M41818
Pathway	REACTOME_CDC42_GTPASE_CYCLE	PIK3R2 ARHGAP17 ARHGAP35	2.73e-03	94	42	3	MM15598
Pathway	WP_FOCAL_ADHESION	MYLK PIK3R2 PIK3R3 ARHGAP35	2.84e-03	199	42	4	M39402
Pathway	KEGG_FOCAL_ADHESION	MYLK PIK3R2 PIK3R3 ARHGAP35	2.84e-03	199	42	4	M7253
Pathway	REACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING	PIK3R2 PIK3R3	2.90e-03	27	42	2	M921
Pathway	PID_TRAIL_PATHWAY	PIK3R2 PIK3R3	3.12e-03	28	42	2	M79
Pathway	KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	MYLK PIK3R2 PIK3R3 ARHGAP35	3.62e-03	213	42	4	M18306
Pathway	PID_ERBB1_DOWNSTREAM_PATHWAY	PIK3R2 PIK3R3 MAPK7	3.73e-03	105	42	3	M164
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MICALL1 SRRM1 CCDC8 RAPH1 SH3PXD2A PRRC2C CD2AP NECTIN2 BAG3 TJP2 KMT2A ARHGAP17 FOXO4 MLXIP	3.79e-11	861	54	14	36931259
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK5 SRRM1 RAPH1 SH3PXD2A PIK3R2 CD2AP BAG3 TJP2 KMT2A ARHGAP17 ARHGAP35 HMGN4 HMGN3 NDUFV3	8.55e-11	916	54	14	32203420
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MICALL1 SRRM1 SCAF1 RAPH1 OTUD5 BAG3 TJP2 KMT2A ZC3H18 ARHGAP35 PRG4	2.48e-08	774	54	11	15302935
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	DOCK5 SRRM1 ATXN7L3 SCAF1 KMT2A ZC3H18 HCFC2 ZCCHC7 MLXIP ZNF281 HMGN4 HMGN3 MEN1	6.60e-08	1294	54	13	30804502
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SRRM1 SCAF1 RAPH1 PRRC2C BAG3 TJP2 ZC3H18 FMNL1	8.56e-08	361	54	8	26167880
Pubmed	Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.	KMT2A HCFC2 MEN1	1.97e-07	8	54	3	31804488
Pubmed	Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.	KMT2A HCFC2 MEN1	2.95e-07	9	54	3	15199122
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DLGAP1 MYLK CD2AP DLGAP4 PRG4 HMGN3 RYR1	7.69e-07	329	54	7	17474147
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	KMT2A HCFC2 FMNL1 MEN1	1.13e-06	50	54	4	37974198
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	SRRM1 SATB2 CBX6 KMT2A ZC3H18 ZNF281 HMGN4 HMGN3	1.62e-06	533	54	8	30554943
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SRRM1 PRAM1 PRRC2C CD2AP KMT2A ZC3H18 ZCCHC7 ZNF281 HMGN4 NDUFV3	1.84e-06	954	54	10	36373674
Pubmed	Interaction of MLL amino terminal sequences with menin is required for transformation.	KMT2A MEN1	2.37e-06	2	54	2	17671196
Pubmed	An MLL-dependent network sustains hematopoiesis.	KMT2A MEN1	2.37e-06	2	54	2	23744037
Pubmed	Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets.	KMT2A MEN1	2.37e-06	2	54	2	27801610
Pubmed	A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection.	ADAM15 ADAM8	2.37e-06	2	54	2	21728902
Pubmed	Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin.	KMT2A MEN1	2.37e-06	2	54	2	27888797
Pubmed	Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.	KMT2A MEN1	2.37e-06	2	54	2	22936661
Pubmed	Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.	KMT2A MEN1	2.37e-06	2	54	2	15640349
Pubmed	Molecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias.	KMT2A MEN1	2.37e-06	2	54	2	20961854
Pubmed	Dependency of B-Cell Acute Lymphoblastic Leukemia and Multiple Myeloma Cell Lines on MEN1 Extends beyond MEN1-KMT2A Interaction.	KMT2A MEN1	2.37e-06	2	54	2	38003662
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2A HCFC2 MEN1	5.34e-06	22	54	3	26886794
Pubmed	Preferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.	SH3PXD2A ADAM15 ADAM8	7.00e-06	24	54	3	25825872
Pubmed	Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis.	SATB2 KIF26A	7.09e-06	3	54	2	36228617
Pubmed	The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.	KMT2A MEN1	7.09e-06	3	54	2	25305204
Pubmed	Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.	KMT2A MEN1	7.09e-06	3	54	2	23908472
Pubmed	Menin critically links MLL proteins with LEDGF on cancer-associated target genes.	KMT2A MEN1	7.09e-06	3	54	2	18598942
Pubmed	SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes.	KMT2A MEN1	7.09e-06	3	54	2	26990989
Pubmed	Menin is necessary for long term maintenance of meningioma-1 driven leukemia.	KMT2A MEN1	7.09e-06	3	54	2	33542482
Pubmed	Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.	KMT2A MEN1	7.09e-06	3	54	2	16604156
Pubmed	Common mechanism for oncogenic activation of MLL by forkhead family proteins.	KMT2A FOXO4	7.09e-06	3	54	2	12393557
Pubmed	The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.	KMT2A MEN1	7.09e-06	3	54	2	16239140
Pubmed	Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.	KMT2A MEN1	7.09e-06	3	54	2	31855575
Pubmed	SATB2 suppresses the progression of colorectal cancer cells via inactivation of MEK5/ERK5 signaling.	SATB2 MAPK7	7.09e-06	3	54	2	25662172
Pubmed	Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.	KMT2A MEN1	7.09e-06	3	54	2	30315824
Pubmed	The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML.	KMT2A MEN1	7.09e-06	3	54	2	34582559
Pubmed	A human MAP kinase interactome.	DLGAP1 KIF26A PIK3R2 BAG3 ARHGAP17 ANKRD24 MAPK7	1.00e-05	486	54	7	20936779
Pubmed	Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.	PIK3R2 CD2AP PIK3R3	1.39e-05	30	54	3	38310234
Pubmed	PI3Kδ and primary immunodeficiencies.	PIK3R2 PIK3R3	1.42e-05	4	54	2	27616589
Pubmed	Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.	KMT2A MEN1	1.42e-05	4	54	2	19703992
Pubmed	A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit.	KMT2A MEN1	1.42e-05	4	54	2	20064463
Pubmed	Haploinsufficient and predominant expression of multiple endocrine neoplasia type 1 (MEN1)-related genes, MLL, p27Kip1 and p18Ink4C in endocrine organs.	KMT2A MEN1	1.42e-05	4	54	2	22037578
Pubmed	The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.	SH3PXD2A ADAM15	1.42e-05	4	54	2	12615925
Pubmed	The ZEB1/miR-200c feedback loop regulates invasion via actin interacting proteins MYLK and TKS5.	MYLK SH3PXD2A	1.42e-05	4	54	2	26334100
Pubmed	The PI3K p110delta controls T-cell development, differentiation and regulation.	PIK3R2 PIK3R3	1.42e-05	4	54	2	17371229
Pubmed	FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis.	FOXO4 PRG4	1.42e-05	4	54	2	29444976
Pubmed	c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development.	KMT2A MEN1	1.42e-05	4	54	2	20484083
Pubmed	miR-24 regulates menin in the endocrine pancreas.	KMT2A MEN1	1.42e-05	4	54	2	24824656
Pubmed	MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.	KMT2A MEN1	1.42e-05	4	54	2	26927674
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	SH3PXD2A PIK3R2 CD2AP PIK3R3	2.05e-05	103	54	4	21706016
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	RAPH1 PRRC2C CD2AP BAG3 ARHGAP35	2.18e-05	216	54	5	31519766
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RAPH1 PRRC2C CD2AP BAG3 TJP2 KMT2A ARHGAP35	2.19e-05	549	54	7	38280479
Pubmed	ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23.	ADAM15 ADAM8	2.36e-05	5	54	2	17072319
Pubmed	Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.	KMT2A MEN1	2.36e-05	5	54	2	21670200
Pubmed	Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.	DLGAP1 DLGAP4	2.36e-05	5	54	2	15024750
Pubmed	Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK.	PIK3R2 PIK3R3	2.36e-05	5	54	2	35429500
Pubmed	The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.	PIK3R2 PIK3R3	2.36e-05	5	54	2	20200404
Pubmed	Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations.	PIK3R2 PIK3R3	2.36e-05	5	54	2	11172806
Pubmed	MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function.	KMT2A FOXO4	2.36e-05	5	54	2	12192052
Pubmed	nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP).	DLGAP1 DLGAP4	2.36e-05	5	54	2	10521485
Pubmed	MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.	KMT2A MEN1	2.36e-05	5	54	2	28609655
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	MICALL1 SRRM1 RAPH1 ARHGAP17	2.47e-05	108	54	4	19531213
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	CBX6 KMT2A HCFC2 ZNF281	2.65e-05	110	54	4	26841866
Pubmed	Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.	KMT2A MEN1	3.54e-05	6	54	2	25866973
Pubmed	Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival.	PIK3R2 PIK3R3	3.54e-05	6	54	2	10949031
Pubmed	The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.	KMT2A MEN1	3.54e-05	6	54	2	22327296
Pubmed	MLL associates specifically with a subset of transcriptionally active target genes.	KMT2A MEN1	3.54e-05	6	54	2	16199523
Pubmed	Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation.	KMT2A MEN1	3.54e-05	6	54	2	35036869
Pubmed	c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.	KMT2A MEN1	3.54e-05	6	54	2	20093773
Pubmed	Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.	ADAM15 ADAM8	3.54e-05	6	54	2	19574220
Pubmed	The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase.	PIK3R2 PIK3R3	3.54e-05	6	54	2	7542745
Pubmed	The emerging mechanisms of isoform-specific PI3K signalling.	PIK3R2 PIK3R3	3.54e-05	6	54	2	20379207
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	CD2AP KMT2A HCFC2 MEN1	3.61e-05	119	54	4	23508102
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SCAF1 PRRC2C KMT2A ZC3H18 HCFC2	4.46e-05	251	54	5	31076518
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	CCDC8 SEMA6D PIK3R2 DLGAP4 PIK3R3 NECTIN2	4.80e-05	421	54	6	36976175
Pubmed	SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation.	KMT2A MEN1	4.94e-05	7	54	2	19818711
Pubmed	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.	DLGAP1 DLGAP4	4.94e-05	7	54	2	9115257
Pubmed	Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome Overview	MYLK LMOD1	4.94e-05	7	54	2	31070878
Pubmed	Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK.	PIK3R2 PIK3R3	4.94e-05	7	54	2	9178903
Pubmed	Abundance of ADAM-8, -9, -10, -12, -15 and -17 and ADAMTS-1 in mouse uterus during the oestrous cycle.	ADAM15 ADAM8	4.94e-05	7	54	2	15907280
Pubmed	Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.	DLGAP1 DLGAP4	4.94e-05	7	54	2	10527873
Pubmed	Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.	KMT2A MEN1	4.94e-05	7	54	2	36098964
Pubmed	Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.	KMT2A MEN1	4.94e-05	7	54	2	16618927
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GARIN5B SRRM1 MYLK RAPH1 SH3PXD2A PRRC2C KMT2A HMGN4 HMGN3 MEN1	6.58e-05	1442	54	10	35575683
Pubmed	Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes.	PIK3R2 PIK3R3	6.59e-05	8	54	2	22402981
Pubmed	Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.	PIK3R2 PIK3R3	6.59e-05	8	54	2	17846664
Pubmed	Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma.	SH3PXD2A ADAM15	6.59e-05	8	54	2	18296648
Pubmed	Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.	ADAM15 ADAM8	6.59e-05	8	54	2	17344430
Pubmed	Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin.	PIK3R2 PIK3R3	8.46e-05	9	54	2	12470648
Pubmed	Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23.	ADAM15 ADAM8	8.46e-05	9	54	2	12777399
Pubmed	Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits.	DLGAP1 SEMA6D	8.46e-05	9	54	2	22911880
Pubmed	The SUMO-specific isopeptidase SENP3 regulates MLL1/MLL2 methyltransferase complexes and controls osteogenic differentiation.	KMT2A MEN1	8.46e-05	9	54	2	24930734
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	SRRM1 SEMA6D RAPH1 NECTIN2 MAPK7 ADAM8 ZNF281 MEN1	8.56e-05	925	54	8	28986522
Pubmed	ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.	MYLK RYR1 MEN1	9.76e-05	57	54	3	23788249
Pubmed	[Detection of fusion genes resulting from chromosome abnormalities in childhood acute lymphoblastic leukemia].	KMT2A FOXO4	1.06e-04	10	54	2	16215946
Pubmed	The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts.	PIK3R2 PIK3R3	1.06e-04	10	54	2	9062339
Pubmed	A novel pro-Arg motif recognized by WW domains.	DLGAP4 ARHGAP17	1.06e-04	10	54	2	10744724
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	CCDC8 CBX6 KMT2A HCFC2 ZNF281 MEN1	1.17e-04	495	54	6	27705803
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MICALL1 SH3PXD2A PRRC2C CD2AP TJP2 ARHGAP35 ZNF281	1.25e-04	724	54	7	36232890
Pubmed	Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.	PIK3R2 PIK3R3	1.29e-04	11	54	2	20598684
Pubmed	Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression.	KMT2A MEN1	1.29e-04	11	54	2	18082152
Interaction	YWHAG interactions	MICALL1 SRRM1 DLGAP1 CCDC8 RAPH1 SH3PXD2A PRRC2C CD2AP NECTIN2 BAG3 TJP2 KMT2A ARHGAP17 FOXO4 MLXIP MAPK7	9.54e-08	1248	54	16	int:YWHAG
Interaction	YWHAH interactions	MICALL1 SRRM1 DLGAP1 CCDC8 SH3PXD2A PRRC2C CD2AP NECTIN2 BAG3 TJP2 KMT2A ARHGAP17 FOXO4 MLXIP MAPK7	1.23e-07	1102	54	15	int:YWHAH
Interaction	YWHAZ interactions	MICALL1 DLGAP1 CCDC8 RAPH1 SH3PXD2A PIK3R2 NECTIN2 BAG3 TJP2 KMT2A FOXO4 ZC3H18 ZCCHC7 MLXIP MAPK7	1.22e-06	1319	54	15	int:YWHAZ
Interaction	RHOB interactions	MICALL1 CCDC8 SEMA6D RAPH1 KIF26A PIK3R2 DLGAP4 NECTIN2 TJP2 ARHGAP17 ARHGAP35 FMNL1	1.73e-06	840	54	12	int:RHOB
Interaction	ARHGAP17 interactions	CD2AP DLGAP4 TJP2 ARHGAP17 FMNL1	6.11e-06	97	54	5	int:ARHGAP17
Interaction	GRB2 interactions	DOCK5 DLGAP1 OTUD5 SH3PXD2A ADAM15 PIK3R2 CD2AP PIK3R3 BAG3 ARHGAP17 ARHGAP35	7.76e-06	806	54	11	int:GRB2
Interaction	SORBS2 interactions	DLGAP1 ADAM15 CD2AP DLGAP4 BAG3	1.18e-05	111	54	5	int:SORBS2
Interaction	YWHAB interactions	MICALL1 DLGAP1 SH3PXD2A PIK3R2 NECTIN2 BAG3 TJP2 KMT2A FOXO4 ZCCHC7 MLXIP MAPK7	1.19e-05	1014	54	12	int:YWHAB
Interaction	SRPK2 interactions	SRRM1 SCAF1 CBX6 PRRC2C BAG3 TJP2 ZC3H18 HMGN3 FMNL1 MEN1	1.77e-05	717	54	10	int:SRPK2
Interaction	LYN interactions	MICALL1 PRAM1 CCDC8 CBX6 ADAM15 PIK3R2 PIK3R3 NECTIN2 KMT2A ZCCHC7	1.84e-05	720	54	10	int:LYN
Interaction	RAC1 interactions	MICALL1 DOCK5 DLGAP1 CCDC8 SEMA6D RAPH1 PIK3R2 DLGAP4 NECTIN2 ARHGAP17 ARHGAP35 FMNL1	1.91e-05	1063	54	12	int:RAC1
Interaction	SH3KBP1 interactions	MICALL1 SRRM1 DLGAP1 RAPH1 CD2AP TJP2 ARHGAP17	2.01e-05	315	54	7	int:SH3KBP1
Interaction	H2BC13 interactions	SCAF1 KMT2A MAPK7 HMGN4 HMGN3 MEN1	2.03e-05	210	54	6	int:H2BC13
Interaction	CRK interactions	DOCK5 PIK3R2 CD2AP PIK3R3 BAG3 ARHGAP17 MEN1	5.60e-05	370	54	7	int:CRK
Interaction	KHDRBS1 interactions	SRRM1 CCDC8 CBX6 SH3PXD2A CD2AP PIK3R3 MEN1	5.89e-05	373	54	7	int:KHDRBS1
Interaction	SRC interactions	CCDC8 MYLK SH3PXD2A ADAM15 CD2AP PIK3R3 KMT2A ARHGAP17 ARHGAP35	6.12e-05	664	54	9	int:SRC
Interaction	H1-2 interactions	SRRM1 SCAF1 CBX6 KMT2A LMOD1 FOXO4 ZC3H18 PRG4 FMNL1	6.26e-05	666	54	9	int:H1-2
Interaction	SSRP1 interactions	SRRM1 SCAF1 SATB2 OTUD5 KMT2A ZC3H18 HMGN4 FMNL1 MEN1	7.77e-05	685	54	9	int:SSRP1
Interaction	H2BC21 interactions	ATXN7L3 SFRP4 CBX6 KMT2A ZC3H18 HCFC2 HMGN4 HMGN3 MEN1	8.77e-05	696	54	9	int:H2BC21
Interaction	TJP2 interactions	CD2AP NECTIN2 TJP2 ARHGAP17 ARHGAP35 MEN1	1.17e-04	288	54	6	int:TJP2
Interaction	H2BC18 interactions	GARIN5B DLGAP4 MAPK7 HMGN4 HMGN3	1.19e-04	180	54	5	int:H2BC18
Interaction	CDC42 interactions	MICALL1 CCDC8 MYLK RAPH1 SH3PXD2A PIK3R2 NECTIN2 ARHGAP17 ZC3H18 ARHGAP35 FMNL1 NDUFV3	1.59e-04	1323	54	12	int:CDC42
Interaction	H2BC9 interactions	SCAF1 DLGAP4 MLXIP MAPK7 HMGN4 HMGN3 NDUFV3	1.79e-04	446	54	7	int:H2BC9
Interaction	MYO5A interactions	DLGAP1 CCDC8 MYLK ZC3H18 MAPK7	2.14e-04	204	54	5	int:MYO5A
Interaction	H2BC12 interactions	SRRM1 SCAF1 KMT2A MAPK7 HMGN4 HMGN3	2.15e-04	322	54	6	int:H2BC12
Interaction	PSIP1 interactions	CD2AP KMT2A ZC3H18 HCFC2 MEN1	2.19e-04	205	54	5	int:PSIP1
Interaction	TCERG1 interactions	MICALL1 ZC3H18 ARHGAP35 FMNL1 MEN1	2.29e-04	207	54	5	int:TCERG1
Interaction	BAG2 interactions	DOCK5 OTUD5 PRRC2C BAG3 ARHGAP17 ARHGAP35 MAPK7 MEN1	2.34e-04	622	54	8	int:BAG2
Interaction	NUP43 interactions	SRRM1 SCAF1 PRRC2C KMT2A ZC3H18 HCFC2 ZCCHC7 ZNF281	2.42e-04	625	54	8	int:NUP43
Interaction	H2BC5 interactions	SCAF1 KMT2A ZC3H18 MAPK7 HMGN4 HMGN3	2.50e-04	331	54	6	int:H2BC5
Interaction	AFDN interactions	CCDC8 SH3PXD2A NECTIN2 TJP2 KMT2A MEN1	2.58e-04	333	54	6	int:AFDN
Interaction	SRSF5 interactions	SRRM1 SCAF1 CBX6 KMT2A ZC3H18 HMGN4 MEN1	2.59e-04	474	54	7	int:SRSF5
Interaction	SOS1 interactions	SRRM1 PIK3R2 CD2AP ARHGAP35	2.73e-04	117	54	4	int:SOS1
Interaction	SMC5 interactions	SRRM1 PRAM1 PRRC2C CD2AP KMT2A ZC3H18 ZCCHC7 ZNF281 HMGN4 NDUFV3	2.82e-04	1000	54	10	int:SMC5
Interaction	TERF2 interactions	PIK3R3 BAG3 ZC3H18 ZNF281 HMGN4 HMGN3	2.88e-04	340	54	6	int:TERF2
Interaction	ZNF131 interactions	CBX6 KMT2A HCFC2 ZNF281	2.91e-04	119	54	4	int:ZNF131
Interaction	CLK1 interactions	SRRM1 RAPH1 BAG3 TJP2 ZC3H18	2.97e-04	219	54	5	int:CLK1
Interaction	PHLDB1 interactions	CCDC8 BAG3 ZC3H18	3.07e-04	49	54	3	int:PHLDB1
Interaction	FOXO1 interactions	SCAF1 SATB2 CD2AP PIK3R3 BAG3 FOXO4	3.21e-04	347	54	6	int:FOXO1
Interaction	SORBS1 interactions	DLGAP1 ADAM15 CD2AP TJP2	3.30e-04	123	54	4	int:SORBS1
Interaction	BRD3 interactions	SRRM1 SCAF1 SATB2 KMT2A ZNF281 HMGN4 HMGN3	3.33e-04	494	54	7	int:BRD3
Interaction	DNMBP interactions	RAPH1 TJP2 ARHGAP17 ARHGAP35	3.40e-04	124	54	4	int:DNMBP
Interaction	RPLP0 interactions	SRRM1 SCAF1 CCDC8 CBX6 KMT2A ZC3H18 ZCCHC7 MEN1	3.49e-04	660	54	8	int:RPLP0
Interaction	RALY interactions	SCAF1 CCDC8 CBX6 ZC3H18 FMNL1 MEN1	3.68e-04	356	54	6	int:RALY
Interaction	RPL36 interactions	SRRM1 SCAF1 CBX6 KMT2A ZC3H18 ZCCHC7 MEN1	3.76e-04	504	54	7	int:RPL36
Interaction	PHF20 interactions	KMT2A HCFC2 MEN1	3.87e-04	53	54	3	int:PHF20
Interaction	PFN1 interactions	RAPH1 BAG3 TJP2 ARHGAP17 ZC3H18 ARHGAP35 FMNL1	3.99e-04	509	54	7	int:PFN1
Interaction	KMT2B interactions	PIK3R3 KMT2A HCFC2 MEN1	4.07e-04	130	54	4	int:KMT2B
Interaction	DLG3 interactions	DLGAP1 DLGAP4 BAG3 ARHGAP17	4.19e-04	131	54	4	int:DLG3
Interaction	PACSIN3 interactions	MICALL1 CCDC8 ADAM15 MEN1	4.19e-04	131	54	4	int:PACSIN3
Interaction	YWHAE interactions	MICALL1 DLGAP1 CCDC8 SH3PXD2A PIK3R2 BAG3 TJP2 KMT2A ZC3H18 MLXIP MAPK7	4.22e-04	1256	54	11	int:YWHAE
Interaction	PRKAR1B interactions	MYO15B SFRP4 DLGAP4 PIK3R3 BAG3	4.35e-04	238	54	5	int:PRKAR1B
Interaction	MYB interactions	SATB2 KMT2A ZNF281 MEN1	4.44e-04	133	54	4	int:MYB
Interaction	PCDHB11 interactions	CCDC8 CBX6 EMILIN2	4.56e-04	56	54	3	int:PCDHB11
Interaction	LOC102724334 interactions	DLGAP4 MAPK7 HMGN4 HMGN3	4.57e-04	134	54	4	int:LOC102724334
Interaction	PLIN1 interactions	RAPH1 SH3PXD2A	4.57e-04	12	54	2	int:PLIN1
Interaction	SFN interactions	SH3PXD2A PRRC2C CD2AP TJP2 KMT2A FOXO4 ZC3H18 ZCCHC7	4.78e-04	692	54	8	int:SFN
Interaction	PACSIN1 interactions	MICALL1 ARHGAP17 ANKRD24	5.59e-04	60	54	3	int:PACSIN1
Interaction	RPL8 interactions	SCAF1 CCDC8 CBX6 ZC3H18 ZCCHC7 HMGN4 MEN1	5.61e-04	539	54	7	int:RPL8
Interaction	PUM3 interactions	CBX6 ZC3H18 ZCCHC7 HMGN4 MEN1	5.84e-04	254	54	5	int:PUM3
Interaction	EWSR1 interactions	SRRM1 CCDC8 BAG3 KMT2A ARHGAP17 ZC3H18 ZNF281 HMGN4 MEN1	6.20e-04	906	54	9	int:EWSR1
Interaction	PARP1 interactions	MICALL1 SRRM1 SCAF1 CCDC8 SATB2 OTUD5 BAG3 ZC3H18 ZNF281 HMGN4 FMNL1	6.25e-04	1316	54	11	int:PARP1
Interaction	NONO interactions	SRRM1 CCDC8 OTUD5 ADAM15 KMT2A ZC3H18 MEN1	6.26e-04	549	54	7	int:NONO
Interaction	H2BC4 interactions	SCAF1 KMT2A ZC3H18 HMGN3 MEN1	6.38e-04	259	54	5	int:H2BC4
Interaction	TIMM50 interactions	CCDC8 CBX6 ZC3H18 MAPK7 MEN1	6.61e-04	261	54	5	int:TIMM50
Interaction	HMGN3 interactions	PRRC2C HMGN4 HMGN3	6.75e-04	64	54	3	int:HMGN3
Interaction	YWHAQ interactions	DLGAP1 CCDC8 SH3PXD2A PIK3R2 NECTIN2 BAG3 TJP2 KMT2A ZCCHC7 MLXIP	6.80e-04	1118	54	10	int:YWHAQ
Interaction	CALD1 interactions	SRRM1 PRRC2C TJP2 KMT2A LMOD1	7.08e-04	265	54	5	int:CALD1
Interaction	ASH2L interactions	SRRM1 KMT2A HCFC2 FMNL1 MEN1	7.08e-04	265	54	5	int:ASH2L
Interaction	CGN interactions	MICALL1 CCDC8 SH3PXD2A TJP2	7.34e-04	152	54	4	int:CGN
Cytoband	2q33	SATB2 RAPH1	5.40e-04	29	54	2	2q33
Cytoband	Ensembl 112 genes in cytogenetic band chr10q26	HMX3 BAG3 ADAM8	1.89e-03	207	54	3	chr10q26
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	GARIN5B SCAF1 CCDC8 NECTIN2 ARHGAP35 RYR1	2.70e-03	1192	54	6	chr19q13
Cytoband	17q25.1	ST6GALNAC1 MYO15B	4.15e-03	81	54	2	17q25.1
Cytoband	22q13.1	MICALL1 CBX6	4.55e-03	85	54	2	22q13.1
GeneFamily	Canonical high mobility group	HMGN4 HMGN3	2.22e-04	11	37	2	511
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM15 ADAM8	1.38e-03	27	37	2	47
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP17 ARHGAP35	4.69e-03	50	37	2	721
Coexpression	GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN	ATXN7L3 RAPH1 PIK3R3 MAPK7 ZNF281	5.74e-05	200	54	5	M5059
Coexpression	GSE31082_DN_VS_DP_THYMOCYTE_DN	OTUD5 PIK3R3 FOXO4 MAPK7 FMNL1	5.74e-05	200	54	5	M5055
Coexpression	GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_DN	DLGAP1 RAPH1 TJP2 MAPK7 ADAM8	5.74e-05	200	54	5	M8007
Coexpression	GSE14350_IL2RB_KO_VS_WT_TREG_DN	RAPH1 CBX6 ADAM8 PRG4 HMGN3	5.74e-05	200	54	5	M3422
Coexpression	GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_UP	MYLK SH3PXD2A PIK3R2 LMOD1 ZNF281	5.74e-05	200	54	5	M8469
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 PRAM1 EMILIN2 ADAM8 FMNL1	1.71e-06	165	54	5	4fe7c3c9370a556cf4e308a2e723b4b907a6cc25
ToppCell	facs-SCAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP4 ADAM15 EMILIN2 PRG4 HMGN3	2.62e-06	180	54	5	6c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell	ILEUM-non-inflamed-(6)_ILC3\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DOCK5 PRAM1 OTUD5 NECTIN2 HMGN3	3.49e-06	191	54	5	6eaf72b41084404bee0db04e4605db745a74995f
ToppCell	Skin-Mesangial\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	SEMA6D MYLK LMOD1 ANKRD24 FMNL1	4.27e-06	199	54	5	bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 PRAM1 EMILIN2 ADAM8	3.94e-05	157	54	4	9d4308312301cb922f156a7b6aededc9e1c62807
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	DLGAP1 TJP2 FOXO4 RYR1	4.35e-05	161	54	4	347edb0de10850b7d16c40945751033289289c9b
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK5 EMILIN2 FMNL1 RYR1	4.56e-05	163	54	4	bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK5 EMILIN2 FMNL1 RYR1	4.67e-05	164	54	4	11dfd84f5fb90de330858e1e852848832734e004
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8 FMNL1	4.67e-05	164	54	4	45a6d809d92fd4eee906da3c812282bacffc9f2f
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8 FMNL1	4.67e-05	164	54	4	aa4358311fc767c292897e3328309d1bcda392d4
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRAM1 EMILIN2 ADAM8 FMNL1	5.01e-05	167	54	4	1bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	BAG3 TJP2 FOXO4 RYR1	5.01e-05	167	54	4	013971700e80b71e4b8c79b8fff0d8beeac295c3
ToppCell	droplet-Lung-nan-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8 FMNL1	5.13e-05	168	54	4	da1eee804456d910c17f145a5ce79c74a808a2c2
ToppCell	facs-BAT-Fat-18m-Myeloid\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8 FMNL1	5.62e-05	172	54	4	8e91831804a120037c71cd4e74af686f3c32d31c
ToppCell	facs-BAT-Fat-18m-Myeloid-myeloid_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8 FMNL1	5.62e-05	172	54	4	ea4da9aab7a2ff854df21da01d11c9ed99e41fb4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CBX6 LMOD1 PROB1	5.75e-05	173	54	4	3001dd39244ef0a5a475d569a78f4ae427a55db6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CBX6 LMOD1 PROB1	5.75e-05	173	54	4	c88883fb2a33e21d4201aa393674aa3f2ad780c9
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRAM1 SATB2 EMILIN2 FMNL1	5.88e-05	174	54	4	d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYLK SH3PXD2A LMOD1 MAPK7	7.00e-05	182	54	4	dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYLK SH3PXD2A LMOD1 MAPK7	7.00e-05	182	54	4	52274af3136d4fd4a495f5882618444661421f0f
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM1 PRRC2C CD2AP ZCCHC7	7.00e-05	182	54	4	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPH1 PRRC2C ADAM15 CD2AP	7.00e-05	182	54	4	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRAM1 EMILIN2 FMNL1 RYR1	7.15e-05	183	54	4	a97f052950429245c3231464271e1ba539863bba
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRAM1 EMILIN2 ADAM8 FMNL1	7.15e-05	183	54	4	cff3197e9ff401362501db2317c86adc6d24b595
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRAM1 EMILIN2 ADAM8 FMNL1	7.15e-05	183	54	4	f803dd2881ceaed6327e21a1a51bc3d3ccf4b5f8
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRAM1 EMILIN2 ADAM8 FMNL1	7.15e-05	183	54	4	4bd6883daf2dbe8c1b49b776b48d41f9890d1cb4
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C CD2AP KMT2A ZCCHC7	7.30e-05	184	54	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DLGAP1 SEMA6D MYLK LMOD1	7.93e-05	188	54	4	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SEMA6D MYLK CBX6 LMOD1	8.10e-05	189	54	4	da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PRAM1 EMILIN2 ADAM8 FMNL1	8.26e-05	190	54	4	ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFRP4 KIF26A ADAM15 PIK3R3	8.26e-05	190	54	4	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CCDC8 SATB2 SFRP4 SEMA6D	8.78e-05	193	54	4	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRAM1 EMILIN2 FMNL1 RYR1	8.95e-05	194	54	4	96f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCell	nucseq-Immune-Immune_Myeloid-pMON-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DOCK5 PRAM1 EMILIN2 FMNL1	8.95e-05	194	54	4	e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell	nucseq-Immune-Immune_Myeloid-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DOCK5 PRAM1 EMILIN2 FMNL1	8.95e-05	194	54	4	0bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRAM1 EMILIN2 FMNL1 RYR1	9.13e-05	195	54	4	91a3c439f10c03c5d51d904f512b6a08040edc76
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK5 PRAM1 EMILIN2 FMNL1	9.13e-05	195	54	4	1d58585557bf8e9ce4d514e128d3a902b526331d
ToppCell	ILEUM-inflamed-(6)_ILC3\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DOCK5 PRAM1 OTUD5 HMGN3	9.13e-05	195	54	4	c6968da7d2b60c2163e1ff0ffa41340e1ec1d2ed
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C KMT2A ZCCHC7 HMGN3	9.13e-05	195	54	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C KMT2A ZCCHC7 HMGN3	9.13e-05	195	54	4	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	COVID-19_Severe-cDC\|COVID-19_Severe / disease group, cell group and cell class	ADAM15 EMILIN2 ADAM8 RYR1	9.13e-05	195	54	4	6419090b19de7b5d5140eaecf231860273da2c0d
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ST6GALNAC1 ADAM15 PIK3R3 TJP2	9.32e-05	196	54	4	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRAM1 EMILIN2 FMNL1 RYR1	9.32e-05	196	54	4	4370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	OTUD5 CBX6 ADAM15 BAG3	9.32e-05	196	54	4	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-cDC2\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRAM1 EMILIN2 ADAM8 FMNL1	9.32e-05	196	54	4	f667430a61bc962e4d033818a05348bf40762041
ToppCell	Fetal_29-31_weeks-Immune-monocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PRAM1 EMILIN2 ADAM8 FMNL1	9.50e-05	197	54	4	48a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRAM1 EMILIN2 FMNL1 RYR1	9.69e-05	198	54	4	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ST6GALNAC1 ADAM15 PIK3R3 TJP2	9.69e-05	198	54	4	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells-mDC\|LPS_only / Treatment groups by lineage, cell group, cell type	CBX6 ADAM8 HMGN3 FMNL1	9.69e-05	198	54	4	53c22e81e530d6fc272d4a45c8d1bf125feb254d
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	DLGAP1 SATB2 PRRC2C KMT2A	9.69e-05	198	54	4	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	5'-Parenchyma_lung-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP4 MYLK LMOD1 PRG4	9.69e-05	198	54	4	aae663c6da70b6e716edeed50cc7d3962d78e697
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	DOCK5 PRAM1 EMILIN2 FMNL1	9.69e-05	198	54	4	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK5 SFRP4 SEMA6D SH3PXD2A	9.88e-05	199	54	4	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SFRP4 MYLK LMOD1 HMGN3	9.88e-05	199	54	4	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRAM1 EMILIN2 FMNL1 RYR1	9.88e-05	199	54	4	744b63fba33b176ab7dde11646ccb313665505f7
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	SFRP4 MYLK CBX6 LMOD1	1.01e-04	200	54	4	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	mild-Non-classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DOCK5 PRAM1 RAPH1 EMILIN2	1.01e-04	200	54	4	334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SFRP4 MYLK LMOD1 HMGN3	1.01e-04	200	54	4	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	SFRP4 MYLK LMOD1 HMGN3	1.01e-04	200	54	4	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	SFRP4 MYLK LMOD1 HMGN3	1.01e-04	200	54	4	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	SFRP4 MYLK LMOD1 HMGN3	1.01e-04	200	54	4	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	BAG3 TJP2 RYR1	4.16e-04	120	54	3	20a815879d45fb9b03df50dc99f95564358c58f2
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_activated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PIK3R2 ADAM8 FMNL1	4.57e-04	124	54	3	e16be7805c91db12b1110c90cd39492913f1d3ea
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	SRRM1 PRRC2C CD2AP	6.25e-04	138	54	3	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SFRP4 MAPK7 MEN1	6.51e-04	140	54	3	0e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCell	P03-Hematopoietic\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EMILIN2 FMNL1 RYR1	6.65e-04	141	54	3	4a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCell	PND14-Immune-Immune_Myeloid-Granulocytic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRAM1 EMILIN2 ADAM8	6.79e-04	142	54	3	bf3537bec0eca9f90c00df9ba840c371f1c9856e
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYLK LMOD1 PRG4	6.93e-04	143	54	3	39060dc1d87505a16e2df95140087c731f099570
ToppCell	Myeloid-E_(Neutrophils)\|World / shred on cell class and cell subclass (v4)	PRAM1 ADAM8 FMNL1	7.21e-04	145	54	3	6ae7dbc62116b4d0610fb55703679488e8da4733
ToppCell	facs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l8\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRAM1 ADAM8 FMNL1	7.80e-04	149	54	3	0f9d2209e8a02371b9f93c0a2fb6f79a4ce48ef1
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MYLK PRRC2C LRTM2	7.80e-04	149	54	3	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	7.95e-04	150	54	3	34774b015adecc2be56a471fda8994e89a6ad93e
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EMILIN2 FMNL1 RYR1	7.95e-04	150	54	3	b37f538ca5f976b509efe35dc81115b72b227084
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EMILIN2 FMNL1 RYR1	7.95e-04	150	54	3	2c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ZNF827 PRRC2C KMT2A	8.11e-04	151	54	3	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	SFRP4 MYLK PRG4	8.11e-04	151	54	3	5906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAM8 FMNL1 RYR1	8.26e-04	152	54	3	b2e29fbda6b5f2d87cfc05423caf9cbf3b04ac65
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 RYR1	8.91e-04	156	54	3	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	facs-Spleen-nan-3m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	8.91e-04	156	54	3	f532ef4e92ac7661b1a8a4f2e98d80ce8d4e3655
ToppCell	facs-Spleen-nan-3m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	8.91e-04	156	54	3	da4f35353a84d919e683554932f110e29568df33
ToppCell	facs-Spleen-nan-3m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	8.91e-04	156	54	3	f1e25ff85c5f2f8555f9fb5ae5daed7ddb418fd1
ToppCell	facs-Lung-Endomucin_-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	9.07e-04	157	54	3	2b60de520edf167f5ca790b478557a778435b3d9
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK5 EMILIN2 FMNL1	9.24e-04	158	54	3	121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MYLK BAG3 ARHGAP17	9.24e-04	158	54	3	de65af8d3b8514b17978155f31975e2347b75251
ToppCell	facs-Lung-EPCAM-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	9.41e-04	159	54	3	baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	9.41e-04	159	54	3	9eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	RAPH1 CD2AP NECTIN2	9.41e-04	159	54	3	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK5 EMILIN2 FMNL1	9.58e-04	160	54	3	bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 RYR1	9.58e-04	160	54	3	1f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	9.76e-04	161	54	3	e227f7b711475624cf80e77f235b1783d88d57b4
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 EMILIN2 ADAM8	9.76e-04	161	54	3	8280a029026c272cae9649b27575831b0dd4e242
ToppCell	facs-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 ADAM8	9.76e-04	161	54	3	45591addc765760db6029ac19e80573373d1d917
ToppCell	facs-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 ADAM8	9.76e-04	161	54	3	8741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCell	lymphoid-B_cell-pro-B\|World / Lineage, cell class and subclass	SFRP4 MYLK MLXIP	9.76e-04	161	54	3	23138e579f07d5a6f20d41457cb573b4ac95a4ef
ToppCell	facs-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 ADAM8	9.76e-04	161	54	3	9cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell	facs-Lung-nan-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 FMNL1	9.93e-04	162	54	3	3fd6aaf0fbaffc7ab38aa25e46c37ef511e1e704
ToppCell	facs-Lung-nan-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 FMNL1	9.93e-04	162	54	3	8134f73eb76693f4f1845f643042fdc1e81c274c
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRAM1 EMILIN2 ADAM8	9.93e-04	162	54	3	ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRAM1 EMILIN2 ADAM8	9.93e-04	162	54	3	4e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK5 EMILIN2 FMNL1	1.01e-03	163	54	3	04152557aae230e9587fcc16cbabf1247cc5b419
Disease	Megacystis microcolon intestinal hypoperistalsis syndrome	MYLK LMOD1	1.97e-05	4	54	2	C1608393
Disease	megacystis-microcolon-intestinal hypoperistalsis syndrome (is_implicated_in)	MYLK LMOD1	3.28e-05	5	54	2	DOID:0060610 (is_implicated_in)
Disease	serum alanine aminotransferase measurement	DLGAP1 ZNF827 PIK3R2 CD2AP NECTIN2 TJP2 MLXIP	9.96e-04	869	54	7	EFO_0004735
Disease	nicotine use, generational effect measurement, illegal drug consumption, non-substance related disinhibited behaviour, alcohol drinking, alcohol dependence	ZNF827 LRTM2	1.29e-03	29	54	2	EFO_0004329, EFO_0005430, EFO_0005431, EFO_0005432, EFO_0008364, MONDO_0007079
Disease	serum gamma-glutamyl transferase measurement	SEMA6D ZNF827 ADAM15 PIK3R3 NECTIN2 KMT2A ARHGAP35	1.33e-03	914	54	7	EFO_0004532
Disease	eyelid sagging measurement	DLGAP1 SFRP4	1.57e-03	32	54	2	EFO_0009360
Disease	asphyxia neonatorum	SEMA6D ZCCHC7	1.57e-03	32	54	2	EFO_1000824
Disease	frontotemporal dementia	SFRP4 NECTIN2	1.57e-03	32	54	2	MONDO_0017276

Protein segments in the cluster

Peptide	Gene	Start	Entry
KPPPAPLVAPSPGKA	CBX6	236	O95503
SPKSQGPAKPPPPRK	ADAM15	806	Q13444
RAPPPVPKKPAKGPA	DLGAP1	911	O14490
LDKDFPKPKKPPPPA	CD2AP	331	Q9Y5K6
KPAAPQVPPKKPTPP	CD2AP	381	Q9Y5K6
KPTFAPPVPPVKPGA	ADAM8	776	P78325
APKKRKAPPPPASIP	ANKRD24	301	Q8TF21
EEKKPPPPVPKKPAK	DLGAP4	921	Q9Y2H0
PPPVPKKPAKSKPAV	DLGAP4	926	Q9Y2H0
SNKKKKPKPPAPPTP	ATXN7L3	326	Q14CW9
AAPPTPTPPVPPAKK	RAPH1	801	Q70E73
ESKPEEPPPPKKPAL	MEN1	491	O00255
PPPVSEPAPPKKDGA	MAPK7	456	Q13164
PVPEKVPPPKPATPD	MYLK	966	Q15746
KKVKPHPPPSGLPPC	HCFC2	111	Q9Y5Z7
PPPPAPKESPFSIKN	HMX3	21	A6NHT5
APKKKPSVLPAPPEG	FOXO4	211	P98177
KGSPKPSPQPSPKPS	LMOD1	506	P29536
SAKPAPPKPEPKPRK	HMGN3	31	Q15651
KPAPPKPEPRPKKAS	HMGN4	31	O00479
ASKRKKPHPPPPPAT	KIF26A	316	Q9ULI4
PKPSEGTPAPRKDPP	MICALL1	356	Q8N3F8
TSKPRKPPTPPEKPQ	MYO15B	926	Q96JP2
EVAPPALPPKPPKAK	PIK3R2	296	O00459
PKQPHKIVPAPKPEP	MLXIP	551	Q9HAP2
ALPPKPPKPMTSAVP	PIK3R3	36	Q92569
EAKAPPPPPPKARKS	DOCK5	1846	Q9H7D0
PGKGEPPAPKSPPKA	FMNL1	1021	O95466
KTTPSEPKKKQPPPP	KMT2A	1321	Q03164
EPKKKQPPPPESGPE	KMT2A	1326	Q03164
AKAPSPPPPAEAPKE	EMILIN2	786	Q9BXX0
KVEVKVPPAPVPCPP	BAG3	361	O95817
KSTPHPPQPPKKPKE	CCDC8	61	Q9H0W5
PPKKQAPPSPPPKKE	RYR1	4521	P21817
KKKPPPPDADPANEP	OTUD5	6	Q96G74
GPPCTKASPEPAKPK	LRTM2	266	Q8N967
KASPEPAKPKPGAEP	LRTM2	271	Q8N967
PPKPKDPVSAAVPAP	ARHGAP17	576	Q68EM7
QPEPSDLPKKPPKPE	PRAM1	26	Q96QH2
KPPPPEVTDLPKKPS	PRAM1	106	Q96QH2
EKTEKKDLPPPPPPP	PRRC2C	1051	Q9Y520
PPPPPPTEDSCAKKP	SATB2	601	Q9UPW6
PKEKKPQATPPPAPF	ST6GALNAC1	226	Q9NSC7
PKPKTPPTAPEPAAA	PROB1	816	E7EW31
KVPPPVKPKPPVHFE	ARHGAP35	1036	Q9NRY4
TPKEPAPTTPKKPAP	PRG4	431	Q92954
PTTPKEPAPTAPKKP	PRG4	476	Q92954
APKKPAPTTPKEPAP	PRG4	486	Q92954
PKEPAPTTPKKPAPT	PRG4	831	Q92954
SPPPAFKPEPPKAKT	TJP2	986	Q9UDY2
AKVPSTPPPKAAPPP	SCAF1	971	Q9H7N4
KVPPPAPPSKPKEAE	SH3PXD2A	521	Q5TCZ1
SNPPKPKGKPPAPKP	SFRP4	311	Q6FHJ7
PKGKPPAPKPASPKK	SFRP4	316	Q6FHJ7
SPEPAAKKPPAPPSP	SRRM1	756	Q8IYB3
PPPPAPDMTFKKEPA	ZNF281	91	Q9Y2X9
PPPPSEKKPEKVTPP	ZNF827	316	Q17R98
KPGPPKKPKTPSRPS	ZCCHC7	331	Q8N3Z6
PSLKPDVPPKPSFVP	SEMA6D	1046	Q8NFY4
SVKKPAPPPAPPQAT	ZC3H18	636	Q86VM9
KASAVPAPPQKTPPP	GARIN5B	491	Q8N5Q1
RPPQAPKKSPKAPPP	KIAA1522	951	Q9P206
KQSPPKKPAPVPAEP	NDUFV3	51	P56181
EGPPSYKPPTPKAKL	NECTIN2	401	Q92692