Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylinositol-4-phosphate binding	OSBP SH3PXD2A OBSCN	1.32e-04	36	55	3	GO:0070273
GeneOntologyMolecularFunction	oxalate transmembrane transporter activity	SLC26A5 SLC26A9	3.31e-04	10	55	2	GO:0019531
GeneOntologyMolecularFunction	chloride:bicarbonate antiporter activity	SLC26A5 SLC26A9	5.70e-04	13	55	2	GO:0140900
GeneOntologyMolecularFunction	bicarbonate:monoatomic anion antiporter activity	SLC26A5 SLC26A9	5.70e-04	13	55	2	GO:0140829
GeneOntologyMolecularFunction	sulfate transmembrane transporter activity	SLC26A5 SLC26A9	8.72e-04	16	55	2	GO:0015116
GeneOntologyMolecularFunction	sterol binding	OSBP OSBPL2 OSBP2	9.90e-04	71	55	3	GO:0032934
GeneOntologyMolecularFunction	phosphatidylinositol binding	OSBP OSBPL2 PIK3C2A SH3PXD2A OBSCN	1.75e-03	316	55	5	GO:0035091
GeneOntologyMolecularFunction	phosphatidylinositol-5-phosphate binding	SH3PXD2A OBSCN	1.82e-03	23	55	2	GO:0010314
GeneOntologyMolecularFunction	sterol transfer activity	OSBP OSBPL2	2.15e-03	25	55	2	GO:0120015
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	OSBP OSBPL2 SH3PXD2A OBSCN	2.19e-03	199	55	4	GO:1901981
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate binding	OSBPL2 SH3PXD2A OBSCN	2.29e-03	95	55	3	GO:0005546
GeneOntologyMolecularFunction	dicarboxylic acid transmembrane transporter activity	SLC26A5 SLC26A9	3.29e-03	31	55	2	GO:0005310
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC26A5 SLC26A9	3.50e-03	32	55	2	GO:0015106
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC26A5 SLC26A9	3.50e-03	32	55	2	GO:0005452
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	SH3PXD2A OBSCN	4.18e-03	35	55	2	GO:0043325
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate binding	OSBPL2 SH3PXD2A OBSCN	4.53e-03	121	55	3	GO:1902936
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	GABRG1 SLC26A5 SLC26A9	4.96e-03	125	55	3	GO:0015108
GeneOntologyCellularComponent	perinuclear endoplasmic reticulum	OSBP OSBPL2 OSBP2	6.68e-05	29	57	3	GO:0097038
Domain	Oxysterol-bd	OSBP OSBPL2 OSBP2	5.51e-06	12	56	3	IPR000648
Domain	Oxysterol-bd_CS	OSBP OSBPL2 OSBP2	5.51e-06	12	56	3	IPR018494
Domain	Oxysterol_BP	OSBP OSBPL2 OSBP2	5.51e-06	12	56	3	PF01237
Domain	OSBP	OSBP OSBPL2 OSBP2	5.51e-06	12	56	3	PS01013
Domain	STAS	SLC26A5 SLC26A9	4.77e-04	11	56	2	PS50801
Domain	STAS_dom	SLC26A5 SLC26A9	4.77e-04	11	56	2	IPR002645
Domain	SLC26A/SulP_dom	SLC26A5 SLC26A9	4.77e-04	11	56	2	IPR011547
Domain	STAS	SLC26A5 SLC26A9	4.77e-04	11	56	2	PF01740
Domain	SLC26A/SulP_fam	SLC26A5 SLC26A9	4.77e-04	11	56	2	IPR001902
Domain	-	SLC26A5 SLC26A9	4.77e-04	11	56	2	3.30.750.24
Domain	Sulfate_transp	SLC26A5 SLC26A9	4.77e-04	11	56	2	PF00916
Domain	-	GBE1 FUCA2	7.85e-04	14	56	2	2.60.40.1180
Domain	Glyco_hydro_b	GBE1 FUCA2	9.04e-04	15	56	2	IPR013780
Domain	-	ACACB EHHADH	1.79e-03	21	56	2	3.90.226.10
Domain	ClpP/crotonase-like_dom	ACACB EHHADH	1.79e-03	21	56	2	IPR029045
Domain	-	GBE1 FUCA2	4.93e-03	35	56	2	3.20.20.80
Domain	Glyco_hydro_catalytic_dom	GBE1 FUCA2	5.79e-03	38	56	2	IPR013781
Pubmed	A family of 12 human genes containing oxysterol-binding domains.	OSBP OSBPL2 OSBP2	9.09e-07	12	57	3	11735225
Pubmed	An oxysterol-binding protein family identified in the mouse.	OSBP OSBPL2 OSBP2	9.09e-07	12	57	3	12215260
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	ACACB OBSCN AGFG1 SORBS1 MGA DNAH9	1.94e-06	226	57	6	31452512
Pubmed	Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina.	OSBP OSBP2	2.64e-06	2	57	2	11278871
Pubmed	Molecular mechanism of NPF recognition by EH domains.	EPS15 AGFG1	2.64e-06	2	57	2	11062555
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	EPS15 NEO1 PRDX4 TUT7 SEC16A AGFG1 C1orf52 NCKAP5L MGA	2.85e-06	733	57	9	34672954
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	EPS15 PIK3C2A SEC16A AGFG1	2.95e-06	60	57	4	34761192
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	OSBP ACACB PIK3C2A PRDX4 SEC16A AGFG1 C1orf52 GBE1 FUCA2 ANKRD27	4.98e-06	1007	57	10	34597346
Pubmed	Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.	EPS15 PIK3C2A SEC16A	6.29e-06	22	57	3	26950368
Pubmed	Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia.	XDH ITPA	7.91e-06	3	57	2	18823306
Pubmed	Sterol liganding of OSBP-related proteins (ORPs) regulates the subcellular distribution of ORP-VAPA complexes and their impacts on organelle structure.	OSBP OSBPL2	7.91e-06	3	57	2	25681634
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ACACB PIK3C2A SH3PXD2A SEC16A SORBS1 CEP192 NCKAP5L	8.28e-06	446	57	7	24255178
Pubmed	VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.	OSBP OSBPL2 OSBP2	9.36e-06	25	57	3	24885147
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ACACB DHX37 PRDX4 TUT7 SORBS1 CEP192 SUFU NCKAP5L MGA	9.65e-06	853	57	9	28718761
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 PIK3C2A SH3PXD2A SEC16A AGFG1 SORBS1 CEP192 NCKAP5L ANKRD27	1.04e-05	861	57	9	36931259
Pubmed	Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.	PIK3C2A PRDX4 SEC16A	1.06e-05	26	57	3	24067654
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	PIK3C2A SEC16A CEP192 NCKAP5L MGA	1.31e-05	184	57	5	32908313
Pubmed	The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport.	EPS15 AGFG1	1.58e-05	4	57	2	10613896
Pubmed	Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization.	EPS15 AGFG1	1.58e-05	4	57	2	9446614
Pubmed	A four-gene signature predicts survival in clear-cell renal-cell carcinoma.	PIK3C2A ITPA	1.58e-05	4	57	2	27779101
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	NEO1 PIK3C2A SUPT6H PEG3 OBSCN SORBS1 MGA	1.66e-05	497	57	7	23414517
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	OBSCN ROBO2 CEP192 NCKAP5L	2.35e-05	101	57	4	10997877
Pubmed	OSBP-related proteins (ORPs) in human adipose depots and cultured adipocytes: evidence for impacts on the adipocyte phenotype.	OSBPL2 OSBP2	2.63e-05	5	57	2	23028956
Pubmed	Family of human oxysterol binding protein (OSBP) homologues. A novel member implicated in brain sterol metabolism.	OSBP OSBPL2	3.94e-05	6	57	2	10588946
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	LIG3 SEC16A SUFU NCKAP5L MGA ZNF292	4.80e-05	398	57	6	35016035
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	EPS15 PRDX4 SEC16A CEP192 NDUFA10	5.38e-05	247	57	5	32989298
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EPS15 ACACB RGPD3 SEC16A NDUFA10 MGA	6.29e-05	418	57	6	34709266
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	PHF2 PIK3C2A EHHADH DHX37 PRDX4 TUT7 PEG3 SEC16A NDUFA10 ITPA	6.99e-05	1371	57	10	36244648
Pubmed	The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.	OSBPL2 OSBP2	7.34e-05	8	57	2	17428193
Pubmed	Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting.	PEG3 ALPL	7.34e-05	8	57	2	15215868
Pubmed	ORP/Osh mediate cross-talk between ER-plasma membrane contact site components and plasma membrane SNAREs.	OSBP OSBPL2	9.43e-05	9	57	2	32734583
Pubmed	Physiological roles and regulation of mammalian sulfate transporters.	SLC26A5 SLC26A9	9.43e-05	9	57	2	11581495
Pubmed	Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.	EPS15 AGFG1	9.43e-05	9	57	2	9303539
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	SUPT6H RGPD3 SEC16A MGA	9.90e-05	146	57	4	23892456
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	PIK3C2A NBEAL1 DHX37 AGFG1 ANKRD27	1.05e-04	285	57	5	34369648
Pubmed	Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.	EPS15 AGFG1	1.18e-04	10	57	2	27237791
Pubmed	N-glycosylation and topology of the human SLC26 family of anion transport membrane proteins.	SLC26A5 SLC26A9	1.18e-04	10	57	2	24647542
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EPS15 NEO1 PIK3C2A SUPT6H PRDX4 C1orf52 CEP192 ZFC3H1 NCKAP5L ATP5PD	1.37e-04	1487	57	10	33957083
Pubmed	The OSBP-related protein family in humans.	OSBPL2 OSBP2	1.44e-04	11	57	2	11483621
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	PIK3C2A SH3PXD2A DHX37 AGFG1 ZFC3H1 MGA ZNF292	1.76e-04	724	57	7	36232890
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	PIK3C2A PRDX4 SEC16A AGFG1 NDUFA10	1.86e-04	322	57	5	39098523
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	LIG3 SUPT6H DHX37 SEC16A MGA ITPA ALPL	2.26e-04	754	57	7	35906200
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	EPS15 NEO1 OSBPL2 ACACB SEC16A CEP192 MGA	2.71e-04	777	57	7	35844135
Pubmed	E3-independent monoubiquitination of ubiquitin-binding proteins.	EPS15 UBE2H	2.73e-04	15	57	2	17588522
Pubmed	Interaction network of human early embryonic transcription factors.	LIG3 ACACB SEC16A MGA ATP5PD	2.77e-04	351	57	5	38297188
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	RGPD3 PEG3 MGA	3.88e-04	86	57	3	37253089
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	SUPT6H SEC16A AGFG1 SORBS1 CEP192 NCKAP5L	3.98e-04	588	57	6	38580884
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PHF2 FSIP2 LIG3 DHX37 MGA ZNF292	4.74e-04	608	57	6	36089195
Pubmed	Human transcription factor protein interaction networks.	PHF2 LIG3 ACACB DHX37 SEC16A CEP192 SUFU MGA ATP5PD	4.94e-04	1429	57	9	35140242
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	EPS15 PIK3C2A SH3PXD2A SEC16A	5.59e-04	230	57	4	35449600
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PHF2 EPS15 PIK3C2A SUPT6H PRDX4 RGPD3 ZFC3H1 NDUFA10 ATP5PD	6.90e-04	1497	57	9	31527615
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZFC3H1 MGA ZNF292	6.95e-04	105	57	3	9628581
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	EPS15 ACACB AGFG1 SUFU MGA	6.97e-04	430	57	5	35044719
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	EPS15 SH3PXD2A PRDX4 SEC16A SUFU MGA ATP5PD	7.22e-04	916	57	7	32203420
Pubmed	Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.	SH3PXD2A SORBS1	7.73e-04	25	57	2	16374509
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	LIG3 EPS15 RGPD3 SEC16A MGA	8.04e-04	444	57	5	34795231
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PHF2 LIG3 SEC16A AGFG1 NDUFA10 MGA ATP5PD	9.16e-04	954	57	7	36373674
Pubmed	ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization.	SLC26A5 ROBO2	9.71e-04	28	57	2	36074819
Pubmed	Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.	GABRG1 PROX2	1.04e-03	29	57	2	37192624
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	FSIP2 DNAH9 ZNF292	1.10e-03	123	57	3	26912792
Pubmed	The transcription factor gene Nfib is essential for both lung maturation and brain development.	NEO1 ROBO2	1.11e-03	30	57	2	15632069
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	EPS15 PRDX4 PEG3 ATP5PD ALPL	1.15e-03	481	57	5	28190767
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	EPS15 SEC16A CEP192	1.15e-03	125	57	3	29467281
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	P3H3 PRDX4 FUCA2 ATP5PD	1.24e-03	285	57	4	32838362
Pubmed	Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.	LIG3 SEC16A GBE1	1.32e-03	131	57	3	34551306
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACB DHX37 OBSCN SORBS1 ZNF292	1.33e-03	497	57	5	36774506
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PHF2 SEC16A CEP192 SUFU NCKAP5L ATP5PD PTPN20	1.58e-03	1049	57	7	27880917
Pubmed	Axon guidance genes control hepatic artery development.	NEO1 ROBO2	1.60e-03	36	57	2	37497580
Cytoband	2p23.1	GALNT14 XDH	4.22e-05	8	57	2	2p23.1
Cytoband	3p12.3	GBE1 ROBO2	2.29e-04	18	57	2	3p12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr10q24	SH3PXD2A SORBS1 SUFU	1.71e-03	189	57	3	chr10q24
Cytoband	Ensembl 112 genes in cytogenetic band chr3p12	GBE1 ROBO2	3.76e-03	73	57	2	chr3p12
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBP OSBPL2 OSBP2	2.18e-06	12	40	3	670
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	LIG3 ZFC3H1	4.92e-04	15	40	2	26
GeneFamily	Fibronectin type III domain containing	NEO1 OBSCN ROBO2	5.29e-03	160	40	3	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NEO1 OBSCN ROBO2	5.38e-03	161	40	3	593
CoexpressionAtlas	kidney_adult_RenalCortexMixed_Std_k-means-cluster#4_top-relative-expression-ranked_500	EHHADH AOAH FUCA2 GCNT1 ALPL	3.31e-05	142	55	5	gudmap_kidney_adult_RenalCortexMixed_Std_k4_500
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	NEO1 P3H3 SH3PXD2A PEG3 ALPL	3.82e-06	184	57	5	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 SH3PXD2A PEG3 SEC16A SEZ6L2	4.82e-06	193	57	5	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 SH3PXD2A PEG3 SEC16A SEZ6L2	4.82e-06	193	57	5	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 SEC16A ROBO2 MGA SEZ6L2	5.07e-06	195	57	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 SH3PXD2A PEG3 ROBO2 SEZ6L2	5.07e-06	195	57	5	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 SEC16A ROBO2 MGA SEZ6L2	5.07e-06	195	57	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	NEO1 SH3PXD2A PEG3 ALPL	5.25e-05	160	57	4	ab769516f9f7798d1390ef215caf22a2d3d53e63
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLC26A9 OSBP2 SEZ6L2 ALPL	6.35e-05	168	57	4	e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLC26A9 OSBP2 SEZ6L2 ALPL	6.35e-05	168	57	4	16b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHF2 OSBP PIK3C2A SH3PXD2A	7.27e-05	174	57	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	NEO1 SH3PXD2A PEG3 ALPL	8.47e-05	181	57	4	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OSBP P3H3 XDH ZFC3H1	9.03e-05	184	57	4	a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ACACB OBSCN GBE1 SORBS1	9.03e-05	184	57	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 PEG3 SEZ6L2 DNAH9	9.03e-05	184	57	4	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NBEAL1 SLC26A9 SEZ6L2 ALPL	9.22e-05	185	57	4	7460387f48f33674330bd53b759681b264228f5a
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	ERN1 SLC26A9 SORBS1 ALPL	9.61e-05	187	57	4	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3PXD2A PEG3 SEC16A SEZ6L2	9.81e-05	188	57	4	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACACB SH3PXD2A AGFG1 GCNT1	1.02e-04	190	57	4	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 SH3PXD2A PEG3 ROBO2	1.04e-04	191	57	4	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	NEO1 PEG3 XDH ROBO2	1.04e-04	191	57	4	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 SH3PXD2A PEG3 ROBO2	1.06e-04	192	57	4	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	UBE2H PIK3C2A SORBS1 ZFC3H1	1.06e-04	192	57	4	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PROX2 SLC26A5 XDH LIPK	1.09e-04	193	57	4	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3PXD2A PEG3 SEC16A SEZ6L2	1.11e-04	194	57	4	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERN1 NBEAL1 SLC26A9 ALPL	1.11e-04	194	57	4	54975e663ed4414b99b3c9a1aa6335613946470f
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3PXD2A PEG3 SEC16A SEZ6L2	1.11e-04	194	57	4	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERN1 NBEAL1 SLC26A9 ALPL	1.15e-04	196	57	4	a6a52cafd7c9994bc3d2f68b15a1491cd96ef908
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Sc17a7.Oprk1_(Claustrum?)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FSIP2 SLC26A5 LIPK	1.17e-04	74	57	3	c26fdce3f979a2f5280a6adcc980419389aec3cb
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Sc17a7.Oprk1_(Claustrum?)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FSIP2 SLC26A5 LIPK	1.17e-04	74	57	3	0feb6bd4c4277f62a4f596370c00ed64e79a389b
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Sc17a7.Oprk1_(Claustrum?)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FSIP2 SLC26A5 LIPK	1.17e-04	74	57	3	4908cbf8ef5881a01a58c26076bd263f8a5665c2
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	DHX37 TUT7 ZFC3H1 ZNF292	1.17e-04	197	57	4	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	P3H3 SH3PXD2A ROBO2 SEZ6L2	1.20e-04	198	57	4	196257c4420ac801ed9fbb444f11718adb7560ae
Disease	Liver Diseases, Parasitic	PEG3 ROBO2	1.26e-04	9	56	2	C0023897
Disease	Autistic Disorder	UBE2H XDH ROBO2 SEZ6L2 ZNF292	1.38e-04	261	56	5	C0004352
Disease	electrocardiography	LIG3 EPS15 SH3PXD2A OBSCN ZFC3H1 SUFU	4.95e-04	530	56	6	EFO_0004327
Disease	Intrahepatic Cholangiocarcinoma	PEG3 ROBO2	9.51e-04	24	56	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	PEG3 ROBO2	9.51e-04	24	56	2	C3805278
Disease	urate measurement, bone density	FSIP2 AOAH SLC26A5 SEC16A GBE1 DNAH9	1.11e-03	619	56	6	EFO_0003923, EFO_0004531
Disease	Cholangiocarcinoma	PEG3 ROBO2	1.12e-03	26	56	2	C0206698
Disease	Thrombocytopenia	XDH ITPA	1.39e-03	29	56	2	C0040034

Protein segments in the cluster

Peptide	Gene	Start	Entry
PETKLDKKKYPYWPH	ATP5PD	141	O75947
EEPPKEFKIWKSNYV	C1orf52	91	Q8N6N3
TKKDPDYLKLWLDTF	NBEAL1	16	Q6ZS30
KPKPLTYWKDVLLLE	P3H3	436	Q8IVL6
QALFKLWGSPDKYPK	ACACB	1726	O00763
LWGSPDKYPKDILTY	ACACB	1731	O00763
YPLPKETWKFTLQKA	AOAH	126	P28039
KKWNSKLYDLPDEPF	ANKRD27	921	Q96NW4
KELPSKSWREPKPEY	NCKAP5L	1036	Q9HCH0
QKYPLLKEPQWKYPD	MGA	541	Q8IWI9
IPLKLKPDYWSDKLQ	MGA	2401	Q8IWI9
VKEAPNKYPLKTWFD	FSIP2	1211	Q5CZC0
KPDPWLSKFLSRYRK	EHHADH	591	Q08426
FKDKPLAEWLRKYNP	PIK3C2A	1206	O00443
CVYDPKKFEWKELAP	KLHL40	481	Q2TBA0
KIPSWLKVNKIYYPD	LIG3	756	P49916
PYKALWFERKKDPVT	OSBP	766	P22059
SAKLLWKKYPLPENA	OSBP2	781	Q969R2
KPKKSWAPNLYELDS	PEG3	11	Q9GZU2
EDIEYLKFDKGPWLK	NDUFA10	271	O95299
KWYLENIYPELSIPK	GALNT14	401	Q96FL9
WYKDDTPLSPSEKFK	OBSCN	2501	Q5VST9
YHYWPISLKKPLELK	PTPN20	266	Q4JDL3
DSDPSWKKPIYKIIS	PROX2	561	Q3B8N5
NSLVPEKEKDPKYWR	ALPL	16	P05186
KEPPLWYAEFTKEEL	RGPD3	1641	A6NKT7
TPDVWYTSKPKEKLV	FUCA2	381	Q9BTY2
KLDYGKWELYIPPKQ	GBE1	116	Q04446
YPKNEIEYKWKKPSV	GABRG1	211	Q8N1C3
IEYKWKKPSVEVADP	GABRG1	216	Q8N1C3
KKPSVEVADPKYWRL	GABRG1	221	Q8N1C3
WKYPFPKETEAKSKL	ERN1	266	O75460
KPEYVKPDFRWSKDP	CEP192	1126	Q8TEP8
PYIKWFLEKLKPEGL	ITPA	86	Q9BY32
PWAVKPEDKAKYDAI	EPS15	121	P42566
YIDPETKKFEPWSKL	DNAH9	2421	Q9NYC9
KFKKRPRWTPDDYIN	GCNT1	81	Q02742
LAAWKKNPKYLLAEY	DHX37	1121	Q8IY37
YWPDDALLAKPKVTK	PHF2	221	O75151
LSKAKISKPAPYWEG	PRDX4	76	Q13162
LPVLSWLPKYKIKDY	SLC26A9	56	Q7LBE3
WLPKYKIKDYIIPDL	SLC26A9	61	Q7LBE3
PITKWLPAYKFKEYV	SLC26A5	66	P58743
AYSEPSPKIEWKKDG	NEO1	76	Q92859
YKGNSKDVKPPDLWI	NEO1	1151	Q92859
KWSDRVPKCALKYEP	SEZ6L2	756	Q6UXD5
YPKLKFWGKSVEAEP	OSBPL2	201	Q9H1P3
YEKKRWYVPPEQAKV	AGFG1	121	P52594
PKWRKKLPGYTDAAL	SUPT6H	196	Q7KZ85
WKVRVDLPDKYPFKS	UBE2H	51	P62256
RWLPGKKKTEAYLPD	SEC16A	2111	O15027
LDPAKYARWKPWLKP	PRPH2	86	P23942
WAPASYIDKRKKPNL	SH3PXD2A	496	Q5TCZ1
WEPPDKKVDTRKYRA	SORBS1	516	Q9BX66
EYSWPEKKLKVSILP	SUFU	461	Q9UMX1
YAEKWKTSEDPLPLL	ZNF292	61	O60281
RLEPYKKKNPSGSWE	XDH	1101	P47989
PEPTIYWKKDKVRID	ROBO2	161	Q9HCK4
KPAKYWKLDPAQVYA	TMEM222	101	Q9H0R3
KDWPKKRIAIEDPYS	TUT7	586	Q5VYS8
TPPFTTYKDKRKWKP	ZFC3H1	1276	O60293
AWYLQKPGKSPKLFL	IGKV1D-42	56	A0A075B6H8
KHLKLSPKSPEYWAF	LIPK	126	Q5VXJ0