Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	5.03e-10	431	101	16	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5 ADGRL3	4.18e-07	884	101	18	GO:0004930
GeneOntologyMolecularFunction	odorant binding	OR8K1 OR5H15 OR5H14 OR12D2 OR5H8 OR5H2 OR5H1	3.74e-06	127	101	7	GO:0005549
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 IL1RL1 OR5H1 OR4K15 OR4C5 ADGRL3 EPHA8	1.22e-05	1353	101	20	GO:0004888
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	PDK2 ZAP70 PIK3R4 MYO3A BRD2 PIK3C2B PIK3CA PI4KA PRKCE MARK2 TAF1L EPHA8	2.42e-04	709	101	12	GO:0016773
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3C2B PIK3CA PI4KA	3.00e-04	26	101	3	GO:0052742
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD3 BRD2 TAF1L	4.62e-04	30	101	3	GO:0070577
GeneOntologyMolecularFunction	kinase activity	PDK2 ZAP70 PIK3R4 MYO3A BRD2 PIK3C2B PIK3CA PI4KA PRKCE MARK2 TAF1L EPHA8	4.75e-04	764	101	12	GO:0016301
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD3 BRD2 TAF1L	5.09e-04	31	101	3	GO:0140033
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 3-kinase activity	PIK3C2B PIK3CA	5.23e-04	7	101	2	GO:0035005
GeneOntologyMolecularFunction	protein kinase activity	PDK2 ZAP70 PIK3R4 MYO3A BRD2 PIK3CA PRKCE MARK2 TAF1L EPHA8	9.20e-04	600	101	10	GO:0004672
GeneOntologyMolecularFunction	lipid kinase activity	PIK3C2B PIK3CA PI4KA	1.16e-03	41	101	3	GO:0001727
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3C2B PIK3CA	1.35e-03	11	101	2	GO:0016303
GeneOntologyBiologicalProcess	sensory perception of smell	OR8K1 GJB4 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 CNGA4 OR4C5	1.30e-11	465	102	18	GO:0007608
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8K1 GJB4 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 CNGA4 OR4C5	2.13e-11	547	102	19	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	2.37e-10	485	102	17	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	3.80e-10	432	102	16	GO:0050911
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	7.73e-10	524	102	17	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	3.75e-09	582	102	17	GO:0050906
GeneOntologyBiologicalProcess	sensory perception	OR8K1 GJB4 OR5H15 OR5H14 OR4K14 OR10G6 MYO3A OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 ZFHX2 OR5H2 OR4C12 OR4K5 LUM OR5H1 OR4K15 CNGA4 OR4C5	1.01e-08	1072	102	22	GO:0007600
GeneOntologyBiologicalProcess	detection of stimulus	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	8.79e-08	722	102	17	GO:0051606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 RGS6 OR12D2 OR4A8 OR5H8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5 ADGRL3	4.77e-05	1395	102	19	GO:0007186
GeneOntologyBiologicalProcess	cytokinesis	DCDC1 APC MEI1 IQGAP1 PIK3R4 TAS1R2 PRKCE	6.97e-05	204	102	7	GO:0000910
GeneOntologyBiologicalProcess	phosphatidylinositol-3-phosphate biosynthetic process	PIK3R4 PIK3C2B PIK3CA	1.69e-04	22	102	3	GO:0036092
GeneOntologyBiologicalProcess	piRNA processing	PIWIL4 TDRD6 TDRD12	1.69e-04	22	102	3	GO:0034587
GeneOntologyBiologicalProcess	phosphatidylinositol-mediated signaling	PIK3C2B PIK3CA PI4KA	2.20e-04	24	102	3	GO:0048015
GeneOntologyBiologicalProcess	positive regulation of fibroblast migration	APC ARHGEF7 PRKCE	3.15e-04	27	102	3	GO:0010763
GeneOntologyBiologicalProcess	phosphatidylinositol phosphate biosynthetic process	PIK3R4 PIK3C2B PIK3CA PI4KA	3.21e-04	66	102	4	GO:0046854
GeneOntologyCellularComponent	pole plasm	PIWIL4 HELZ TDRD6	3.65e-04	29	101	3	GO:0045495
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex	PIK3R4 PIK3C2B PIK3CA	3.65e-04	29	101	3	GO:0005942
GeneOntologyCellularComponent	germ plasm	PIWIL4 HELZ TDRD6	3.65e-04	29	101	3	GO:0060293
GeneOntologyCellularComponent	P granule	PIWIL4 HELZ TDRD6	3.65e-04	29	101	3	GO:0043186
MousePheno	sclera thinning	FMOD LUM	2.47e-05	2	70	2	MP:0003102
Domain	Olfact_rcpt	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	1.74e-08	393	98	14	IPR000725
Domain	PI3Ka	PIK3C2B PIK3CA PI4KA	1.15e-05	9	98	3	PF00613
Domain	PI3Ka	PIK3C2B PIK3CA PI4KA	1.15e-05	9	98	3	SM00145
Domain	-	PIK3C2B PIK3CA PI4KA	1.15e-05	9	98	3	1.25.40.70
Domain	7tm_1	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	1.16e-05	677	98	14	PF00001
Domain	ARM-type_fold	RSPH14 DOCK8 APC MEI1 TRIP12 PIK3R4 PIK3C2B PIK3CA PI4KA TBCD	1.16e-05	339	98	10	IPR016024
Domain	G_PROTEIN_RECEP_F1_1	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	1.32e-05	685	98	14	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	1.45e-05	691	98	14	PS50262
Domain	GPCR_Rhodpsn	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	1.48e-05	692	98	14	IPR000276
Domain	PI_Kinase	PIK3C2B PIK3CA PI4KA	1.64e-05	10	98	3	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2B PIK3CA PI4KA	1.64e-05	10	98	3	IPR001263
Domain	PIK_HELICAL	PIK3C2B PIK3CA PI4KA	1.64e-05	10	98	3	PS51545
Domain	PI3/4_kinase_CS	PIK3C2B PIK3CA PI4KA	6.09e-05	15	98	3	IPR018936
Domain	-	PIK3C2B PIK3CA PI4KA	7.47e-05	16	98	3	1.10.1070.11
Domain	PI3Kc	PIK3C2B PIK3CA PI4KA	7.47e-05	16	98	3	SM00146
Domain	PI3_PI4_kinase	PIK3C2B PIK3CA PI4KA	1.08e-04	18	98	3	PF00454
Domain	PI3_4_KINASE_1	PIK3C2B PIK3CA PI4KA	1.08e-04	18	98	3	PS00915
Domain	PI3_4_KINASE_2	PIK3C2B PIK3CA PI4KA	1.08e-04	18	98	3	PS00916
Domain	PI3/4_kinase_cat_dom	PIK3C2B PIK3CA PI4KA	1.08e-04	18	98	3	IPR000403
Domain	PI3_4_KINASE_3	PIK3C2B PIK3CA PI4KA	1.08e-04	18	98	3	PS50290
Domain	BET	BRD3 BRD2	1.62e-04	4	98	2	PF17035
Domain	NET_dom	BRD3 BRD2	1.62e-04	4	98	2	IPR027353
Domain	NET	BRD3 BRD2	1.62e-04	4	98	2	PS51525
Domain	GPCR_Rhodpsn_7TM	OR8K1 OR5H15 OR5H14 OR4K14 OR10AG1 OR12D2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15	1.99e-04	670	98	12	IPR017452
Domain	Bromodomain_CS	BRD3 BRD2 TAF1L	3.34e-04	26	98	3	IPR018359
Domain	ARM-like	RSPH14 DOCK8 APC MEI1 TRIP12 PIK3R4 TBCD	5.51e-04	270	98	7	IPR011989
Domain	PI3K_Ras-bd_dom	PIK3C2B PIK3CA	5.63e-04	7	98	2	IPR000341
Domain	PI3K_rbd	PIK3C2B PIK3CA	5.63e-04	7	98	2	SM00144
Domain	PI3K_rbd	PIK3C2B PIK3CA	5.63e-04	7	98	2	PF00794
Domain	PI3K_RBD	PIK3C2B PIK3CA	5.63e-04	7	98	2	PS51546
Domain	PI3K_C2	PIK3C2B PIK3CA	7.48e-04	8	98	2	SM00142
Domain	PI3K_C2_dom	PIK3C2B PIK3CA	7.48e-04	8	98	2	IPR002420
Domain	PI3K_C2	PIK3C2B PIK3CA	7.48e-04	8	98	2	PF00792
Domain	PI3K_C2	PIK3C2B PIK3CA	7.48e-04	8	98	2	PS51547
Domain	BROMODOMAIN_1	BRD3 BRD2 TAF1L	9.56e-04	37	98	3	PS00633
Domain	RuvA_2-like	ERCC4 SRBD1	9.58e-04	9	98	2	IPR010994
Domain	Bromodomain	BRD3 BRD2 TAF1L	1.03e-03	38	98	3	PF00439
Domain	BROMODOMAIN_2	BRD3 BRD2 TAF1L	1.29e-03	41	98	3	PS50014
Domain	Bromodomain	BRD3 BRD2 TAF1L	1.39e-03	42	98	3	IPR001487
Domain	BROMO	BRD3 BRD2 TAF1L	1.39e-03	42	98	3	SM00297
Domain	-	BRD3 BRD2 TAF1L	1.39e-03	42	98	3	1.20.920.10
Domain	Kinase-like_dom	ZAP70 PIK3R4 MYO3A PIK3C2B PIK3CA PI4KA PRKCE MARK2 EPHA8	2.18e-03	542	98	9	IPR011009
Domain	TUDOR	TDRD6 TDRD12	2.38e-03	14	98	2	PF00567
Domain	-	RSPH14 APC TRIP12 PIK3R4 TBCD	6.30e-03	222	98	5	1.25.10.10
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8K1 OR5H15 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 CNGA4 OR4C5	1.01e-09	417	79	16	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR8K1 PLB1 OR5H15 OR5H14 OR4K14 OR10G6 MYO3A OR10AG1 OR12D2 OR4A8 TAS1R2 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 CNGA4 OR4C5	1.44e-09	636	79	19	M41834
Pathway	PID_CDC42_PATHWAY	APC IQGAP1 PIK3CA ARHGEF7 PRKCE	4.43e-05	70	79	5	M81
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR8K1 OR4K14 OR10AG1 OR12D2 OR2D3 OR5H2 OR4C12 OR4K5 OR4K15 CNGA4	6.02e-05	389	79	10	M14091
Pathway	REACTOME_PHOSPHOLIPID_METABOLISM	PLB1 PIK3R4 PIK3C2B PIK3CA PI4KA ALPP GNPAT	1.12e-04	196	79	7	MM14591
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	APC IQGAP1 PIK3R4 PIK3C2B PIK3CA ARHGEF7	1.93e-04	150	79	6	M39520
Pathway	WP_REGULATION_OF_ACTIN_CYTOSKELETON	APC IQGAP1 PIK3R4 PIK3C2B PIK3CA ARHGEF7	2.07e-04	152	79	6	MM15834
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8K1 OR5H15 OR5H14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	9.82e-14	340	103	15	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8K1 OR5H15 OR5H14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	9.82e-14	340	103	15	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8K1 OR5H15 OR5H14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	1.12e-13	343	103	15	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8K1 OR5H15 OR5H14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR5H1 OR4K15 OR4C5	1.27e-13	346	103	15	14611657
Pubmed	The human olfactory receptor gene family.	OR8K1 OR5H14 OR4K14 OR10G6 OR10AG1 OR12D2 OR4A8 OR5H8 OR2D3 OR5H2 OR4C12 OR4K5 OR4K15 OR4C5	7.97e-10	541	103	14	14983052
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	TTC28 KBTBD6 BRD3 SRBD1 DDX55 TRIP12 PSMD6 BRD2 ARHGEF7 PI4KA CPSF3	3.50e-06	645	103	11	25281560
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RPL30 ERCC4 TTC28 APC DDX55 PIK3R4 ARHGEF7 HELZ MARK2 PZP GNPAT	3.76e-06	650	103	11	38777146
Pubmed	Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.	BRD3 TRIP12 IQGAP1 HELZ	7.45e-06	42	103	4	7584044
Pubmed	Development of myotendinous-like junctions that anchor cardiac valves requires fibromodulin and lumican.	FMOD LUM	8.69e-06	2	103	2	27503167
Pubmed	APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells.	APC PIK3CA	8.69e-06	2	103	2	37968472
Pubmed	Homologous sequence in lumican and fibromodulin leucine-rich repeat 5-7 competes for collagen binding.	FMOD LUM	8.69e-06	2	103	2	19008226
Pubmed	Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice.	FMOD LUM	8.69e-06	2	103	2	12766039
Pubmed	Fibromodulin regulates collagen fibrillogenesis during peripheral corneal development.	FMOD LUM	8.69e-06	2	103	2	20108350
Pubmed	Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene.	BRD3 BRD2	8.69e-06	2	103	2	9373153
Pubmed	IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner.	IQGAP1 PRKCE	8.69e-06	2	103	2	15695813
Pubmed	The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription.	BRD3 BRD2	8.69e-06	2	103	2	18406326
Pubmed	APC and PIK3CA Mutational Cooperativity Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colorectal Liver Metastases.	APC PIK3CA	8.69e-06	2	103	2	28379870
Pubmed	Identification of Lumican and Fibromodulin as Hub Genes Associated with Accumulation of Extracellular Matrix in Diabetic Nephropathy.	FMOD LUM	8.69e-06	2	103	2	33887734
Pubmed	Adhesion of ZAP-70+ chronic lymphocytic leukemia cells to stromal cells is enhanced by cytokines and blocked by inhibitors of the PI3-kinase pathway.	ZAP70 PIK3CA	8.69e-06	2	103	2	23981382
Pubmed	A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice.	FMOD LUM	8.69e-06	2	103	2	12089156
Pubmed	Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons.	FMOD LUM	8.69e-06	2	103	2	11076963
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR5H15 OR5H14 OR12D2 OR5H1	1.08e-05	46	103	4	32126975
Pubmed	Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.	PIK3R4 PIK3C2B PIK3CA	2.36e-05	19	103	3	31959764
Pubmed	Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.	APC BRD3	2.60e-05	3	103	2	37043564
Pubmed	Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo.	APC PIK3CA	2.60e-05	3	103	2	31844152
Pubmed	PIK3CA mutation is a favorable prognostic factor in esophageal cancer: molecular profile by next-generation sequencing using surgically resected formalin-fixed, paraffin-embedded tissue.	APC PIK3CA	2.60e-05	3	103	2	30115035
Pubmed	PIK3CA and APC mutations are synergistic in the development of intestinal cancers.	APC PIK3CA	2.60e-05	3	103	2	23708654
Pubmed	A novel dynein light intermediate chain colocalizes with the retrograde motor for intraflagellar transport at sites of axoneme assembly in chlamydomonas and Mammalian cells.	DYNC2H1 IFT88	2.60e-05	3	103	2	12802074
Pubmed	Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.	BRD3 BRD2	2.60e-05	3	103	2	31792058
Pubmed	Mice expressing activated PI3K rapidly develop advanced colon cancer.	APC PIK3CA	2.60e-05	3	103	2	22525701
Pubmed	Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice.	APC PIK3CA	2.60e-05	3	103	2	24320611
Pubmed	Expression of lumican and fibromodulin following interleukin-1 beta stimulation of disc cells of the human temporomandibular joint.	FMOD LUM	2.60e-05	3	103	2	22073367
Pubmed	Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration.	BRD3 BRD2	2.60e-05	3	103	2	24049186
Pubmed	[Expression of BRD7-interacting proteins,BRD2 and BRD3, in nasopharyngeal carcinoma tissues].	BRD3 BRD2	2.60e-05	3	103	2	12600283
Pubmed	Phylogeny and structure of the RING3 gene.	BRD3 BRD2	2.60e-05	3	103	2	8781126
Pubmed	Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.	APC PIK3CA	2.60e-05	3	103	2	26863299
Pubmed	Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.	BRD3 BRD2	2.60e-05	3	103	2	28945351
Pubmed	The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment.	KBTBD6 KBTBD7	2.60e-05	3	103	2	32572597
Pubmed	BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition.	BRD3 BRD2	2.60e-05	3	103	2	29437854
Pubmed	Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.	PIK3C2B PIK3CA PRKCE	3.23e-05	21	103	3	9446795
Pubmed	Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening.	PIWIL4 IFT88 ARHGEF7 ANKEF1	3.32e-05	61	103	4	35205757
Pubmed	HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.	PIK3C2B PIK3CA PRKCE	3.73e-05	22	103	3	11154208
Pubmed	Genetic heterogeneity in synchronous colorectal cancers impacts genotyping approaches and therapeutic strategies.	APC PIK3CA	5.19e-05	4	103	2	26650777
Pubmed	Expression of BET genes in testis of men with different spermatogenic impairments.	BRD3 BRD2	5.19e-05	4	103	2	22035730
Pubmed	The endoplasmic reticulum-resident collagen chaperone Hsp47 interacts with and promotes the secretion of decorin, fibromodulin, and lumican.	FMOD LUM	5.19e-05	4	103	2	30002123
Pubmed	What are those cilia doing in the neural tube?	DYNC2H1 IFT88	5.19e-05	4	103	2	23351466
Pubmed	Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration.	APC IQGAP1	5.19e-05	4	103	2	15572129
Pubmed	Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence.	APC PIK3CA	5.19e-05	4	103	2	26276752
Pubmed	Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.	BRD3 BRD2	5.19e-05	4	103	2	24248598
Pubmed	Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.	PIK3C2B PIK3CA	5.19e-05	4	103	2	18594509
Pubmed	Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer.	APC PIK3CA	5.19e-05	4	103	2	23499052
Pubmed	Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival.	APC PIK3CA	5.19e-05	4	103	2	26279473
Pubmed	Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors.	BRD3 BRD2	5.19e-05	4	103	2	22912406
Pubmed	An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice.	APC PIK3CA	5.19e-05	4	103	2	22214849
Pubmed	Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.	PIK3C2B PIK3CA PRKCE	5.53e-05	25	103	3	15689238
Pubmed	Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy.	PIK3C2B PIK3CA PRKCE	5.53e-05	25	103	3	17632570
Pubmed	Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.	ONECUT2 FOXN4 ISM1	6.24e-05	26	103	3	28082864
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR5H8 OR5H2 OR5H1	7.01e-05	27	103	3	32061665
Pubmed	Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.	APC PIK3R4	8.64e-05	5	103	2	12388762
Pubmed	Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues.	FMOD LUM	8.64e-05	5	103	2	18620607
Pubmed	Genes encoding proteoglycans are associated with the risk of anterior cruciate ligament ruptures.	FMOD LUM	8.64e-05	5	103	2	24552666
Pubmed	The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly.	FMOD LUM	8.64e-05	5	103	2	23331954
Pubmed	The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer.	APC IL1RL1	8.64e-05	5	103	2	31165767
Pubmed	IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli.	APC IQGAP1	8.64e-05	5	103	2	17255093
Pubmed	Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.	PIK3CA PI4KA	8.64e-05	5	103	2	8246987
Pubmed	Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association.	PRKCE MARK2	8.64e-05	5	103	2	19011111
Pubmed	Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway.	PIK3C2B PIK3CA	8.64e-05	5	103	2	17875942
Pubmed	Molecular characterization of oral squamous cell carcinoma using targeted next-generation sequencing.	APC PIK3CA	1.29e-04	6	103	2	26173098
Pubmed	PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters.	PIK3CA PRKCE	1.29e-04	6	103	2	15213298
Pubmed	PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway.	PIWIL4 TDRD12	1.29e-04	6	103	2	26669262
Pubmed	Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins.	BRD3 BRD2	1.29e-04	6	103	2	31444232
Pubmed	Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development.	FMOD LUM	1.29e-04	6	103	2	24272803
Pubmed	Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation.	KBTBD6 KBTBD7	1.81e-04	7	103	2	33990333
Pubmed	The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification.	DYNC2H1 IFT88	1.81e-04	7	103	2	15121860
Pubmed	Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.	APC ALPP	1.81e-04	7	103	2	26831517
Pubmed	Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells.	PIK3CA PI4KA	1.81e-04	7	103	2	17242350
Pubmed	Histone recognition and large-scale structural analysis of the human bromodomain family.	BRD3 TAF1L	1.81e-04	7	103	2	22464331
Pubmed	Tracing oncogene-driven remodelling of the intestinal stem cell niche.	APC PIK3CA	1.81e-04	7	103	2	34079126
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	ATP13A1 BRD3 RRM1 PIK3R4 OTUD4 MARK2 TBCD	1.94e-04	400	103	7	35013556
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	TTC28 KBTBD6 DYNC2H1 APC SRBD1 TRIP12 IQGAP1 PSMD6 OTUD4 MARK2 ALDH9A1	1.97e-04	1005	103	11	19615732
Pubmed	Personal receptor repertoires: olfaction as a model.	OR12D2 OR4A8 OR4C5	1.97e-04	38	103	3	22908908
Pubmed	BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail.	BRD3 BRD2	2.40e-04	8	103	2	31311807
Pubmed	Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.	PIK3CA PRKCE	2.40e-04	8	103	2	12893243
Pubmed	Regulation of membrane traffic by phosphoinositide 3-kinases.	PIK3R4 PIK3CA	2.40e-04	8	103	2	16467569
Pubmed	Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.	APC PIK3CA	2.40e-04	8	103	2	29170395
Pubmed	Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways.	BRD2 PIK3CA	3.08e-04	9	103	2	9671713
Pubmed	Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines.	APC PIK3CA	3.08e-04	9	103	2	39128004
Pubmed	The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.	PIK3C2B PIK3CA	3.85e-04	10	103	2	8636073
Pubmed	Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.	PIWIL4 TDRD6	3.85e-04	10	103	2	19584108
Pubmed	Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.	PIK3C2B PIK3CA	3.85e-04	10	103	2	8798481
Pubmed	Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.	PIK3C2B PIK3CA	3.85e-04	10	103	2	9247029
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PCGF2 TTC28 ATP13A1 APC SKIL TRIP12 IQGAP1 PIK3R4 BRD2 IFT88 GUCY1B1 TBC1D23	4.25e-04	1285	103	12	35914814
Pubmed	Functional interaction between autophagy and ciliogenesis.	PIK3R4 IFT88	4.69e-04	11	103	2	24089209
Pubmed	The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis.	FMOD LUM	4.69e-04	11	103	2	20696843
Pubmed	HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.	PIK3C2B PIK3CA	4.69e-04	11	103	2	16081599
Pubmed	Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.	BRD3 BRD2	4.69e-04	11	103	2	28805820
Pubmed	HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.	PIK3C2B PIK3CA	4.69e-04	11	103	2	9708406
Pubmed	CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.	KBTBD6 KBTBD7	4.69e-04	11	103	2	25684205
Pubmed	HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.	PIK3C2B PIK3CA	4.69e-04	11	103	2	10985305
Pubmed	Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.	PIK3C2B PIK3CA	4.69e-04	11	103	2	12584329
Cytoband	3q12.1	OR5H15 OR5H14 OR5H8 OR5H2	1.39e-07	21	103	4	3q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3q11	OR5H15 OR5H14 OR5H8 OR5H2 OR5H1	1.49e-07	54	103	5	chr3q11
Cytoband	2q12	ZAP70 IL1RL1	3.24e-04	12	103	2	2q12
Cytoband	14q11.2	OR4K14 ZFHX2 OR4K5 OR4K15	7.47e-04	180	103	4	14q11.2
GeneFamily	Olfactory receptors, family 4	OR4K14 OR4A8 OR4C12 OR4K5 OR4K15 OR4C5	1.71e-05	129	76	6	151
GeneFamily	Olfactory receptors, family 5	OR5H15 OR5H14 OR5H8 OR5H2 OR5H1	1.09e-04	112	76	5	152
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2B PIK3CA	4.80e-04	8	76	2	831
GeneFamily	Small leucine rich repeat proteoglycans	FMOD LUM	1.12e-03	12	76	2	573
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; PC3; HT_HG-U133A	ONECUT2 TMEM144 PCGF2 ZNF268 APC TRAPPC13 AIG1 MARK2	2.20e-06	193	100	8	3814_DN
Disease	blood pressure, response to thiazide, response to beta blocker	OR5H14 OR5H1	3.14e-05	3	96	2	EFO_0004325, EFO_0007766, EFO_0007981
Disease	Glioblastoma Multiforme	PDK2 APC BRD2 PIK3CA TAF1L	3.20e-05	111	96	5	C1621958
Disease	osteoarthritis	DCDC1 ZNF268 SRBD1 GUCY1B1 AIG1 TDRD12	8.94e-05	222	96	6	MONDO_0005178
Disease	HEPATOCELLULAR CARCINOMA	APC PIK3CA	3.72e-04	9	96	2	114550
Disease	Hepatocellular carcinoma	APC PIK3CA	3.72e-04	9	96	2	cv:C2239176
Disease	Childhood Medulloblastoma	APC BRD3 BRD2	3.75e-04	43	96	3	C0278510
Disease	Melanotic medulloblastoma	APC BRD3 BRD2	3.75e-04	43	96	3	C1275668
Disease	Medullomyoblastoma	APC BRD3 BRD2	3.75e-04	43	96	3	C0205833
Disease	Desmoplastic Medulloblastoma	APC BRD3 BRD2	3.75e-04	43	96	3	C0751291
Disease	Adult Medulloblastoma	APC BRD3 BRD2	3.75e-04	43	96	3	C0278876
Disease	Gastric Adenocarcinoma	BRD3 BRD2 EPHA8	4.29e-04	45	96	3	C0278701
Disease	Gastric cancer	APC PIK3CA	5.65e-04	11	96	2	cv:C0024623
Disease	Neoplasm of stomach	APC PIK3CA	5.65e-04	11	96	2	cv:C0038356
Disease	GASTRIC CANCER	APC PIK3CA	5.65e-04	11	96	2	613659
Disease	Adenocarcinoma of lung (disorder)	APC RRM1 PIK3CA TAF1L EPHA8	5.77e-04	206	96	5	C0152013
Disease	Medulloblastoma	APC BRD3 BRD2	5.85e-04	50	96	3	C0025149
Disease	esophageal cancer (is_marker_for)	BHLHE41 PIK3CA	6.77e-04	12	96	2	DOID:5041 (is_marker_for)
Disease	Malformations of Cortical Development	PIK3CA TBCD	9.29e-04	14	96	2	C1955869
Disease	Cortical Dysplasia	PIK3CA TBCD	9.29e-04	14	96	2	C0431380
Disease	Benign neoplasm of stomach	APC PIK3CA	1.38e-03	17	96	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	APC PIK3CA	1.38e-03	17	96	2	C0496905
Disease	Carcinoma in situ of stomach	APC PIK3CA	1.38e-03	17	96	2	C0154060
Disease	allergic disease, age at onset	PLB1 IQGAP1 IL1RL1	1.63e-03	71	96	3	EFO_0004847, MONDO_0005271
Disease	Stomach Carcinoma	APC PIK3CA	2.11e-03	21	96	2	C0699791
Disease	small cell lung carcinoma	DYNC2H1 PIWIL4 RGS6	2.29e-03	80	96	3	EFO_0000702
Disease	breast cancer (implicated_via_orthology)	APC PIK3CA	2.99e-03	25	96	2	DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NCYIYNKPTDDIVLM	BRD3	111	Q15059
KLKDGYYMRPCVLTN	ALDH9A1	366	P49189
SYCSILCNYKAIEMP	AIG1	16	Q9NVV5
RTSCMYGANCYRKNP	APLF	376	Q8IW19
IPIYYASSLAKKCMA	CPSF3	266	Q9UKF6
GLDYSSLYMCKPKRS	BHLHE41	21	Q9C0J9
IALAKLYMYCTEPFR	ATP13A1	506	Q9HD20
AQMENIRCYLPDAYK	ADGRL3	71	Q9HAR2
IRCYLPDAYKIMSQR	ADGRL3	76	Q9HAR2
KDNYYKTPLMTACAS	ANKEF1	521	Q9NU02
QMKTLYLTYCANHPS	ARHGEF7	356	Q14155
TTDIYDRKNMPRCIY	IQGAP1	136	P46940
RCVYLQTSMKYNILP	PZP	1326	P20742
SAMCQSLLYELLYEK	OTUD4	161	Q01804
PENTDYAIYLCKRTM	RGS6	126	P49758
PVCNLMSYTLYSKIL	MFSD8	431	Q8NHS3
ATMAYDRYVAICKPL	OR5H15	116	A6NDH6
ATMAYDRYVAICKPL	OR5H8	116	P0DN80
ATMAYDRYVAICKPL	OR5H14	116	A6NHG9
SYYQARLLSLRMKTC	DCDC1	1381	M0R2J8
LTVMAYDRYVAICKP	OR10AG1	106	Q8NH19
YVAICKPLNYTTIMS	OR4C12	121	Q96R67
FPTAMYCDNRNLKYL	FMOD	86	Q06828
LSYNKIMYFPLGLCA	LRRD1	471	A4D1F6
KFMATYLRQPTYCSH	PRKCE	171	Q02156
QKTPSRLENYYMVCK	DDX55	236	Q8NHQ9
LLYKIQENMRYGCAS	F13B	106	P05160
VSMAYDRYVAICKPL	OR4K5	116	Q8NGD3
LVSMAYDRYVAICKP	OR4K14	116	Q8NGD5
VSMAYDRYVAICKPL	OR4K15	116	Q8NH41
SDMYIICRLKPYSFT	NUDT6	221	P53370
ATMAYDRYVAICKPL	OR5H2	121	Q8NGV7
MKAAYTAYRCLTKDL	ONECUT2	1	O95948
LRDTLYYMKDLPTSF	PI4KA	381	P42356
KINVSEYTYRCLMSP	GUCY1B1	561	Q02153
KPSVYYVMLILCTAS	KCNK13	191	Q9HB14
LYAVNSKRMLCYDPS	KBTBD7	486	Q8WVZ9
AVCKPLYYSTIMTQR	OR2D3	141	Q8NGH3
YLDICYSTVTLPKML	OR12D2	66	P58182
TCKPARMLYRVALLY	HELZ	286	P42694
CDYKDYRETILSKPM	MEDAG	101	Q5VYS4
PLSQYKYIRSCIMLG	PIK3CA	266	P42336
LCDKYYMASPDLEIQ	PDK2	211	Q15119
YYMCLNLLSAPEKTG	MEI1	631	Q5TIA1
ATMAYDRYVAICKPL	OR5H1	116	A6NKK0
ARKTCNPTYNEMLVY	PIK3C2B	1561	O00750
TCIVRYLETNKYCPM	PCGF2	41	P35227
LAMDRFPYVALSKTY	ALPP	91	P05187
CLKLAMPEVQYSNYL	GAL3ST3	381	Q96A11
AYLPLAESASKMYFI	DYNC2H1	3491	Q8NCM8
KKQSDCNVPDYLMYS	IL1RL1	106	Q01638
MAPNLKAGYNLTICY	IFT88	301	Q13099
LMYRIAKSYQASPDL	DOCK8	1626	Q8NF50
SDLKFAMKCYTPLVY	GNPAT	46	O15228
MYECKSQKFNYRTLP	GALNT4	121	Q8N4A0
QPTSLETALKYCNYM	CACNA1I	1511	Q9P0X4
YKKCPAMVRNLAAFS	EPHA8	201	P29322
RLYKDYDMPRVVACS	GJB4	151	Q9NTQ9
SYPSAMYCDELKLKS	LUM	46	P51884
KYRIPFYMSTDCENL	MARK2	266	Q7KZI7
VPSKEAYCAYAIILM	SLC13A2	31	Q13183
YKPTARYCIRSMLSL	ISM1	361	B1AKI9
KPSVDLKICMYDRLY	CFAP74	806	Q9C0B2
LYALNSKRMFCYDPS	KBTBD6	486	Q86V97
RDNNMAPYYEALCKS	PSMD6	46	Q15008
YTLMAYDRFLAICKP	OR10G6	136	Q8NH81
YVATCKPLRYLTIMN	OR4A8	121	P0C604
AICKPLYYLITMNRQ	OR4C5	146	Q8NGB2
YSYSCLIAMALKNSK	FOXN4	196	Q96NZ1
LMSDIQYYCKNTAAP	TDRD6	801	O60522
YLYMCDKVVAPNVSL	SKIL	401	P12757
YALYSKNKPRSDALM	PLEKHG4	821	Q58EX7
RAKVSPEQCCAYYSM	TAF1L	896	Q8IZX4
MQLPYRAKKFSLYCT	TDRD12	116	Q587J7
LVAKNYACYMSPTKN	TDRD12	201	Q587J7
LVMCILPSNQKTYYD	PIWIL4	546	Q7Z3Z4
IAMKNCNTPLLRAYY	MSH4	436	O15457
LSAMAYDRYVAICKP	OR8K1	121	Q8NGG5
MKCPSQESPYLFSYR	PLB1	331	Q6P1J6
LIMKNYFAPLDVVYC	SRBD1	611	Q8N5C6
NCYIYNKPTDDIVLM	BRD2	151	P25440
ADVRLMFSNCYKYNP	BRD2	416	P25440
TCSMPYAKLEYKRSS	APC	946	P25054
TAYPNAFRIAKLMLY	CNGA4	161	Q8IV77
ISTADVYCKLMPYLD	PIK3R4	686	Q99570
QRMRACYYSLASKVE	ZAP70	591	P43403
AQKCLYRSVMLENYS	ZNF268	101	Q14587
QLKIMKACYEAYRTP	ZFHX2	2076	Q9C0A1
PYIDSICYRMITAKA	SPO16	141	Q5VVC0
NCPALRKSEIEYYAM	RPL30	51	P62888
MVRLAVPDSKCVYTY	SMTNL1	461	A8MU46
DQLYQYCSLLIKSMP	THAP9	271	Q9H5L6
GTPYMLYKDSCNRKS	RRM1	401	P23921
SPVCRGNLYKAYMQL	RSPH14	121	Q9UHP6
YFLAYCIAMKNSPKL	TMEM144	246	Q7Z5S9
PRSDLYNCFYAIMNK	TBC1D23	141	Q9NUY8
KSPAMSRYYLELFQC	SLF1	481	Q9BQI6
SRYYLELFQCPTCMK	SLF1	486	Q9BQI6
KCYMILFYPERNTPA	TAS1R2	811	Q8TE23
NCILYSNRSAAYMKI	TTC28	91	Q96AY4
LSYDDPNRKMYHLCI	TTC30A	531	Q86WT1
SALAALCSEYYMKEP	TBCD	731	Q9BTW9
LYSQCISMSRYYKRP	ERCC4	741	Q92889
MDTRQYLYCLKPKNE	TRAPPC13	246	A5PLN9
VMTCVNYLKLPDYSS	TRIP12	1956	Q14669
YCSTRIYASMKCPDQ	TBRG1	216	Q3YBR2
IYASMKCPDQKCLYT	TBRG1	221	Q3YBR2
SLRNYPYKICDSCEM	ZNF248	131	Q8NDW4
YVQPMLSKYAAVCVR	TANGO2	216	Q6ICL3
YYLLCYKSSEEPRMS	MYO3A	1001	Q8NEV4