Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of glomerular filtration

PDGFB F2RL1

2.78e-054452GO:0003104
GeneOntologyCellularComponenthistone methyltransferase complex

PRDM8 PRDM4 RBBP5

5.29e-0475443GO:0035097
GeneOntologyCellularComponenttransferase complex

PRDM8 FBXL16 PRAMEF18 MED23 PRDM4 AMN1 RBBP5 ENC1

7.97e-04963448GO:1990234
GeneOntologyCellularComponentubiquitin ligase complex

FBXL16 PRAMEF18 MED23 AMN1 ENC1

8.34e-04352445GO:0000151
GeneOntologyCellularComponentcullin-RING ubiquitin ligase complex

FBXL16 PRAMEF18 AMN1 ENC1

1.02e-03212444GO:0031461
DomainRA

ARAP3 MYO9A MYO9B

7.70e-0536433PF00788
DomainRA

ARAP3 MYO9A MYO9B

8.36e-0537433PS50200
DomainRA_dom

ARAP3 MYO9A MYO9B

1.06e-0440433IPR000159
DomainLRR_6

FBXL16 CARMIL2 AMN1

2.74e-0455433PF13516
DomainRhoGAP

ARAP3 MYO9A MYO9B

3.91e-0462433SM00324
DomainRhoGAP

ARAP3 MYO9A MYO9B

4.10e-0463433PF00620
DomainRHOGAP

ARAP3 MYO9A MYO9B

4.29e-0464433PS50238
DomainRhoGAP_dom

ARAP3 MYO9A MYO9B

4.29e-0464433IPR000198
Domain-

ARAP3 MYO9A MYO9B

4.29e-04644331.10.555.10
DomainLeu-rich_rpt_Cys-con_subtyp

FBXL16 AMN1

8.64e-0419432IPR006553
DomainLRR_CC

FBXL16 AMN1

8.64e-0419432SM00367
DomainRho_GTPase_activation_prot

ARAP3 MYO9A MYO9B

1.09e-0388433IPR008936
DomainRA

MYO9A MYO9B

2.31e-0331432SM00314
DomainMYOSIN_MOTOR

MYO9A MYO9B

3.45e-0338432PS51456
DomainMyosin_head

MYO9A MYO9B

3.45e-0338432PF00063
DomainMyosin_head_motor_dom

MYO9A MYO9B

3.45e-0338432IPR001609
DomainMYSc

MYO9A MYO9B

3.45e-0338432SM00242
DomainSET

PRDM8 PRDM4

5.03e-0346432SM00317
DomainSET_dom

PRDM8 PRDM4

5.91e-0350432IPR001214
DomainKAZAL_2

CFI RECK

5.91e-0350432PS51465
DomainSET

PRDM8 PRDM4

5.91e-0350432PS50280
DomainKazal_dom

CFI RECK

6.15e-0351432IPR002350
Domain-

FBXL16 CARMIL2 PRAMEF18 AMN1

6.24e-033214343.80.10.10
DomainL_dom-like

FBXL16 CARMIL2 PRAMEF18 AMN1

6.72e-03328434IPR032675
DomainUbiquitin-rel_dom

ARAP3 MYO9A MYO9B

8.69e-03184433IPR029071
DomainZF_DAG_PE_1

MYO9A MYO9B

9.54e-0364432PS00479
DomainZF_DAG_PE_2

MYO9A MYO9B

9.54e-0364432PS50081
DomainC1

MYO9A MYO9B

9.82e-0365432SM00109
DomainPE/DAG-bd

MYO9A MYO9B

1.01e-0266432IPR002219
DomainIQ

MYO9A MYO9B

1.16e-0271432PF00612
Pubmed

Class IX Myosins: Motorized RhoGAP Signaling Molecules.

MYO9A MYO9B

1.64e-06245232451867
Pubmed

Complementary lateral hypothalamic populations resist hunger pressure to balance nutritional and social needs.

LEPR NTS

1.64e-06245236827985
Pubmed

Leptin acts via lateral hypothalamic area neurotensin neurons to inhibit orexin neurons by multiple GABA-independent mechanisms.

LEPR NTS

1.64e-06245225143620
Pubmed

Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling.

PTCH1 LEPR

4.91e-06345216702471
Pubmed

Loss of Action via Neurotensin-Leptin Receptor Neurons Disrupts Leptin and Ghrelin-Mediated Control of Energy Balance.

LEPR NTS

4.91e-06345228323938
Pubmed

Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance.

LEPR NTS

4.91e-06345221907138
Pubmed

Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.

ARAP3 PDGFB

9.81e-06445218765673
Pubmed

FoxO6-mediated IL-1β induces hepatic insulin resistance and age-related inflammation via the TF/PAR2 pathway in aging and diabetic mice.

F2RL1 LEPR

9.81e-06445230974318
Pubmed

BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.

MYO9A MYO9B

9.81e-06445215644318
Pubmed

Yin and Yang of PDGF-mediated signaling pathway in the context of HIV infection and drug abuse.

PDGFB TRPC1

9.81e-06445223784143
Pubmed

TF/FVIIa transactivate PDGFRbeta to regulate PDGF-BB-induced chemotaxis in different cell types: involvement of Src and PLC.

PDGFB F2RL1

1.63e-05545217991872
Pubmed

Vasculature-associated cells expressing nestin in developing bones encompass early cells in the osteoblast and endothelial lineage.

PTCH1 LEPR

1.63e-05545224823376
Pubmed

Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons.

LEPR NTS

2.45e-05645230858605
Pubmed

Tails of unconventional myosins.

MYO9A MYO9B

3.42e-05745211212352
Pubmed

Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad.

PTCH1 PDGFB

4.56e-05845212651897
Pubmed

A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development.

MED23 PTCH1

7.32e-051045221305688
Pubmed

Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.

RBBP5 LEPR

8.94e-051145224051374
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

DOCK3 PTCH1 MYO9A MYO9B

1.26e-0419845420881960
Pubmed

Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

MYO9A MYO9B

1.47e-04144528022818
Pubmed

Radial construction of an arterial wall.

PTCH1 PDGFB

1.70e-041545222975322
Pubmed

The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs.

PTCH1 RECK

1.94e-041645223213437
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK3 PTCH1 PRDM4 ZNF804A PIP4P1

2.30e-0443045535044719
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KRI1 KIFBP FBXL16 TBC1D22A THAP12

2.72e-0444645524255178
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PLEKHH1 KIFBP MED23

3.27e-0410345310574462
Pubmed

F-box protein FBXL16 binds PP2A-B55α and regulates differentiation of embryonic stem cells along the FLK1+ lineage.

FBXL16 RBBP5

4.07e-042345224390425
Pubmed

Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea.

KCNK3 ANO1

4.07e-042345237873566
Pubmed

Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.

PTCH1 PDGFB

5.63e-042745225631042
Pubmed

A genome annotation-driven approach to cloning the human ORFeome.

APOBEC3G PDGFB TBC1D22A MOV10L1

5.67e-0429445415461802
Pubmed

Extra-embryonic vasculature development is regulated by the transcription factor HAND1.

PTCH1 PDGFB

6.06e-042845215073150
Pubmed

The DNA sequence of human chromosome 22.

APOBEC3G PDGFB TBC1D22A MOV10L1

6.12e-0430045410591208
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PCED1A KIFBP PRAMEF18 MED23 MYO9A TBC1D22A ENC1

1.01e-03124245730973865
Cytoband5q13

F2RL1 ENC1

2.14e-04224525q13
CytobandEnsembl 112 genes in cytogenetic band chr22q13

APOBEC3G PDGFB TBC1D22A MOV10L1

3.10e-04330454chr22q13
GeneFamilyMyosins, class IX

MYO9A MYO9B

2.85e-0623121103
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM8 PRDM4

3.81e-04173121197
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 PTCH1 LEPR RECK TRPC1

1.01e-061794557078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 PTCH1 LEPR RECK TRPC1

1.01e-06179455d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 ANO1 PTCH1 GPR173 ENC1

1.07e-06181455d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANO1 PRDM8 IRF2BP1 TRPC1

1.85e-0515645460f1ce38e34b582f589db1e0d6139282c1902b2b
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

APOBEC3G KIFBP ABCA3 ENC1

2.54e-051694540425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

APOBEC3G KIFBP ABCA3 ENC1

2.54e-05169454fec669968a77060bd77ee8695034e35a642c984f
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 ARAP3 GPR173 NTS

2.72e-051724541bad7b19724e1b53ace7e05644215334c9f43910
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-2|TCGA-Colorectal / Sample_Type by Project: Shred V9

APOBEC3G PRDM8 ABCA3 FBXL16

2.97e-051764541870860a9ebe7a655c4ea8898427e1097ee23113
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 FBXL16 TRPC1 NTS

3.25e-051804549db9899ca42455310e9b63df523fe6c4780abfb7
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNK3 DOCK3 ANO1 PTCH1

3.32e-0518145425915e2500430a902db37d79a749ce2990b69810
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 FBXL16 PDGFB NTS

3.61e-051854542a8104f610fa5ce618f8105521616722462a0d42
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNK3 DOCK3 ANO1 ENC1

3.85e-05188454c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNK3 ANO1 PTCH1 ENC1

3.93e-05189454f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

STAB2 PDGFB NTS ENC1

3.93e-051894549a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNK3 DOCK3 ANO1 PTCH1

3.93e-0518945445e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNK3 DOCK3 ANO1 PTCH1

4.09e-0519145414057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANO1 PTCH1 ZNF804A

4.09e-05191454b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellP03-Mesenchymal-developing_mesenchymal_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNK3 LEPR RECK TRPC1

4.18e-05192454063e119c4b58957643908f667e6cfd6f7517fd03
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KCNK3 DOCK3 ANO1 ENC1

4.26e-05193454000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

STAB2 PDGFB LEPR NTS

4.44e-05195454ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCell15-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

KCNK3 ANO1 PTCH1 ENC1

4.53e-051964540e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCelldistal-1-Endothelial-Lymphatic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRDM8 STAB2 CFI NTS

4.71e-05198454b6fea363463c8dd7e6780c085ece4900266a6286
ToppCellASK428-Endothelial|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

STAB2 PDGFB RECK NTS

4.71e-05198454d69d0ff115298596173a4278897a65007a71f5df
ToppCellwk_15-18-Endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

STAB2 ARAP3 LEPR NTS

4.71e-05198454dcf453e22dba90c0ae349fa6c3d4c20758bb95af
ToppCellwk_20-22-Endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

STAB2 ARAP3 PDGFB LEPR

4.80e-0519945407be9509a8ec9c9a7d721912d77c20e841f49808
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRDM8 ARAP3 IRF2BP1 PDGFB

4.89e-05200454fe493b0454a20498e9ada482bf55de64519f6c35
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nts|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO1 F2RL1 NTS

6.49e-0577453dbbefd2dfa4c345172cb5a995952e3682fbadf92
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|367C / Donor, Lineage, Cell class and subclass (all cells)

KCNK3 KRI1 RBBP5

3.13e-04131453cc5b5afab8622e98f673fa116a226d930c295327
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KCNK3 MOV10L1 ENC1

3.65e-041384538d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c3-LAMP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK3 MRPL39 MOV10L1

3.72e-04139453bb2b020dda32ddc60ec9952de5b01acee60b5b59
ToppCelltumor_Lung-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

APOBEC3G STAB2 ENC1

3.96e-04142453eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_small-bowel / Manually curated celltypes from each tissue

APOBEC3G PDGFB ENC1

4.13e-04144453a4bb274d553c29c8299354de757ecc5634008c68
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ZNF804A LEPR

5.12e-041554538fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue

KIFBP CD8B2 RECK

5.31e-04157453c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ANO1 PTCH1 ENC1

5.31e-04157453b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCED1A F2RL1 LEPR

5.31e-04157453a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF804A ARL11 GPR173

5.31e-04157453f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHH1 ABCA3 NTS

5.61e-04160453731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHH1 ABCA3 NTS

5.61e-04160453cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ANO1 VSTM5 NTS

5.72e-04161453bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 PDGFB F2RL1

5.72e-04161453334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 PDGFB F2RL1

5.72e-0416145381d44438e4be4e68a59247e62f02026301a8a0c5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STAB2 MOV10L1 NTS

5.82e-041624532ac02523348660e514d464f8f2434ee0c312d784
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KCNK3 KRI1 RBBP5

5.92e-0416345363b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCellfacs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARAP3 IRF2BP1 PDGFB

6.03e-041644535ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 CFI NTS

6.25e-04166453941d6aa94ab9d36e5f6c40f446c926754e070d56
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 CFI NTS

6.25e-041664536f5ecf3b2cf613ae0535ab3d21d93622f1497571
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARAP3 NTS

6.36e-04167453b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARAP3 NTS

6.36e-0416745326cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARAP3 NTS

6.36e-04167453fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 ARAP3 NTS

6.36e-04167453f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

MED23 F2RL1 RECK

6.47e-041684532781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSTM5 ARAP3 NTS

6.47e-0416845306dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK3 ANO1 PRDM8

6.47e-04168453e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ABCA3 PTCH1 MYO9A

6.47e-04168453c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK3 ANO1 PRDM8

6.47e-04168453b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSTM5 ARAP3 NTS

6.47e-041684531002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

STAB2 MOV10L1 NTS

6.47e-041684534977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

ARAP3 PDGFB MOV10L1

6.58e-04169453e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

ANO1 VSTM5 CFI

6.69e-041704535a64e05c263df915085988d881808221e2c0f2e2
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCED1A PRDM4 AMN1

6.69e-04170453b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLEKHH1 PTCH1 PDGFB

6.69e-0417045355fe16d98ea284d05fb899888e4569c685644c7b
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

STAB2 ARAP3 NTS

6.81e-0417145307ff7059071da83da1d8f266a586573920d75b58
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

KCNK3 KRI1 RBBP5

6.92e-04172453da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellNS-critical-d_0-4-Epithelial-FOXN4+|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IRF2BP1 CFI ZNF804A

6.92e-04172453a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

STAB2 TRPC1 NTS

6.92e-04172453d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRDM8 IRF2BP1 F2RL1

7.04e-041734534968712af1cca8c932abd3323631d7dcaffd4a66
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

STAB2 RECK NTS

7.04e-04173453a81992965137195d20fc498f750975303961a828
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PTCH1 RECK NTS

7.04e-041734537e2149205e119cec4f5099c83c85d1e13470137a
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ARAP3 PDGFB NTS

7.16e-04174453b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

STAB2 MOV10L1 NTS

7.16e-04174453d551bc29afef071adf4c9bb80345352ec33441d8
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

ANO1 PRDM8 NTS

7.16e-041744537d2f802f493f19a068e097b2909a9000e2160266
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 F2RL1 NTS

7.28e-041754530801cccec6915aefc135262fc74580280fd51aa5
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCED1A ARAP3 ENC1

7.28e-04175453c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNK3 RECK TRPC1

7.28e-04175453fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 F2RL1 NTS

7.28e-0417545309163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNK3 ANO1 GPR173

7.28e-041754531b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNK3 RECK TRPC1

7.28e-041754532a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 STAB2 NTS

7.52e-04177453d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

STAB2 MOV10L1 NTS

7.52e-0417745371bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB2 MOV10L1 ENC1

7.52e-041774536d89042bda8e244babb68929e84b25edcb545a77
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB2 MOV10L1 ENC1

7.52e-04177453daaccf1249dcf816df4caca695a944f53078291a
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-mature_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

APOBEC3G PRDM8 ENC1

7.52e-041774530f2616a81f8fbede77c860b2126e3fa826672da3
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB2 MOV10L1 ENC1

7.52e-04177453c5a16f984c836dbf7d0faf061677844167ab612a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

APOBEC3G PDGFB ENC1

7.52e-0417745384930899eb2978598bc8a351cbcd9e714e46799d
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB2 MOV10L1 ENC1

7.52e-04177453338bdda26796bf4e16072878c070212d1006cf57
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 ANO1 TRPC1

7.77e-04179453bfc226bcf0b93525992344f968268a261d86fcbf
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARAP3 TRPC1 ENC1

7.77e-04179453025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 ANO1 TRPC1

7.77e-0417945336ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCNK3 LEPR RECK

7.77e-0417945356db12467b445f2b8ef92af50779eeab10413eb2
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

STAB2 ARAP3 PDGFB

7.77e-04179453d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK3 ANO1 ARAP3

7.90e-0418045379c5725f02e038d0187f4a1e1591f2492538aa57
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ARAP3 LEPR

8.02e-041814532e15c46e8260bb04d8264478c19a707221996026
ToppCelldroplet-Heart-nan-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARAP3 PDGFB NTS

8.02e-04181453859c40889ede2cbf374c4d2efbb72dc3bc6441f5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 ZNF804A NTS

8.02e-04181453062f00736eed96e4f4327615d093558dd7d82b20
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSTM5 F2RL1 NTS

8.02e-04181453cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK3 FBXL16 ENC1

8.15e-04182453be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 ZNF804A NTS

8.15e-04182453d3a037268f026eb2f84428b1821022503cef7756
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 ANO1 F2RL1

8.15e-04182453ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellnormal_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

KCNK3 APOBEC3G ENC1

8.15e-041824530ef8fb13488a65717b050b1b4e4bf062a1553eff
DrugSecurinine [5610-40-2]; Down 200; 18.4uM; PC3; HT_HG-U133A

APOBEC3G PTCH1 PDGFB F2RL1 RECK ENC1

1.47e-061904364493_DN
DrugIAPE

APOBEC3G KIFBP

2.09e-054432CID000131739
DrugClenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; PC3; HT_HG-U133A

STAB2 METTL16 IRF2BP1 PDGFB RECK

3.08e-051934354671_DN
DrugIsosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A

IRF2BP1 PDGFB MYO9B TBC1D22A LEPR

3.24e-051954354742_DN
DrugPrazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; PC3; HT_HG-U133A

APOBEC3G ABCA3 PDGFB MYO9B TBC1D22A

3.32e-051964356315_DN
DrugNiflumic acid [4394-00-7]; Down 200; 14.2uM; PC3; HT_HG-U133A

ABCA3 PTCH1 PDGFB ZNF804A RECK

3.32e-051964355071_DN
DrugCefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; MCF7; HT_HG-U133A

PDGFB MYO9A MYO9B TBC1D22A TRPC1

3.32e-051964357222_DN
DrugFluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; PC3; HT_HG-U133A

APOBEC3G ZNF804A TBC1D22A RECK ENC1

3.32e-051964355741_DN
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

APOBEC3G IRF2BP1 PDGFB TBC1D22A ENC1

3.48e-051984354343_UP
DrugTamoxifen citrate [54965-24-1]; Up 200; 7uM; PC3; HT_HG-U133A

PTCH1 PDGFB MYO9B TBC1D22A RECK

3.56e-051994352050_UP
DrugNaphazoline hydrochloride [550-99-2]; Down 200; 16.2uM; HL60; HG-U133A

KRI1 MED23 MYO9A TBC1D22A ENC1

3.65e-052004351966_DN
DiseaseSchizoaffective disorder-bipolar type

STAB2 PTCH1 ZNF804A

1.59e-0616433EFO_0009965
Diseaseessential hypertension

KCNK3 PRDM8

6.22e-063432MONDO_0001134
DiseasePulmonary Hypertension

KCNK3 ABCA3 LEPR

2.74e-0540433C0020542
Diseaseresponse to calcium channel blocker

KCNK3 DOCK3 ARL11

7.57e-0556433EFO_0007767
Disease4-acetamidobutanoate measurement

TBC1D22A MOV10L1

2.46e-0416432EFO_0021003
DiseaseAstrocytosis

KCNK3 LEPR

2.78e-0417432C3887640
DiseaseGliosis

KCNK3 LEPR

2.78e-0417432C0017639
Diseaseglomerulonephritis (implicated_via_orthology)

CFI PDGFB

2.78e-0417432DOID:2921 (implicated_via_orthology)
Diseaselifestyle measurement

DOCK3 ARAP3 PTCH1 ZNF804A

3.79e-04235434EFO_0010724
Diseasesex interaction measurement, bilirubin measurement

CFI F2RL1

4.70e-0422432EFO_0004570, EFO_0008343
Diseasetreatment-resistant hypertension

KCNK3 DOCK3 ARL11

5.43e-04109433EFO_1002006
Diseasemean arterial pressure, unipolar depression

KCNK3 PRDM8

1.00e-0332432EFO_0003761, EFO_0006340
Diseaseunipolar depression, systolic blood pressure

KCNK3 PRDM8

1.13e-0334432EFO_0003761, EFO_0006335
Diseasepotassium measurement

KCNK3 PRDM8

1.97e-0345432EFO_0009283
Diseasecryptic phenotype measurement

KCNK3 PRDM8

2.15e-0347432EFO_0021487

Protein segments in the cluster

PeptideGeneStartEntry
CKSSWSMREANVACL

CFI

141

P05156
LDLCLWCFMKNISRY

AMN1

11

Q8IY45
QRDMWCSTLQSCLKE

ARAP3

366

Q8WWN8
CVLLLSIWKNNCMTT

CXorf66

6

Q5JRM2
YISWSPCTKCTRDMA

APOBEC3G

91

Q9HC16
NLWFRCLSCVDMKLS

CARMIL2

216

Q6F5E8
YNWMTLSQKLCSCLL

ABCA3

396

Q99758
CRELCTKLYSMSWGN

RECK

301

O95980
LQSLWSLLKSRSCMC

ARL11

166

Q969Q4
SQSCYVWRALCMTLV

MOV10L1

231

Q9BXT6
FQSMCSCLWYKSREK

KCNK3

306

O14649
MNRCWALFLSLCCYL

PDGFB

1

P01127
SCLWDLSRYGRCSME

PCED1A

141

Q9H1Q7
CWLCMIVEFSRYLSQ

PRAMEF18

216

Q5VWM3
GWCLSDTYLKCAMNA

MED23

1041

Q9ULK4
RLRWYSCMLGKKCSL

METTL16

241

Q86W50
CETDGYLTKMTCRWS

LEPR

436

P48357
WCSLKKTCMYRSEQE

KRI1

551

Q8N9T8
LCDKTCSYWKMSSAC

ANO1

381

Q5XXA6
LDCISMALTCTFNRW

RBBP5

21

Q15291
YTLCSSCALNMWLAK

THAP12

356

O43422
CSILFMTCLSVQRYW

F2RL1

161

P55085
CMLLLAFSSWSLCSD

NTS

11

P30990
CEAKISLSNMCIYWL

CD8B2

41

A6NJW9
KELIRCLKWYMDCSA

DOCK3

701

Q8IZD9
CLKWYMDCSAELIRQ

DOCK3

706

Q8IZD9
YAKRMTLWTCAAVIC

GPR173

131

Q9NS66
CTKLYELSWRMCLSN

ENC1

161

O14682
LCLGRALYWACMKVS

PIP4P1

256

Q86T03
ARCWIKYCLTLMQNA

KIFBP

311

Q96EK5
ASRRQWCYLCDLPKM

IRF2BP1

6

Q8IU81
KENMATLFTIWCTLC

PRDM4

366

Q9UKN5
MSSLRSLYLRWCCQV

FBXL16

396

Q8N461
CAMHLSEWYCRKSIL

MRPL39

91

Q9NYK5
EKSSLLMSCLACDTW

RPAIN

201

Q86UA6
MSWKVRVELASCCYF

OR5L1

136

Q8NGL2
WCAKCNASFRMTSDL

PRDM8

626

Q9NQV8
AYACLTMLRWDCSKS

PTCH1

451

Q13635
ICYMISSLSKWICSH

TRPC1

691

P48995
AVLISLMWVCNKCAY

VSTM5

161

A8MXK1
EMKLGTCVSCSLVYW

STAB2

671

Q8WWQ8
LCNIEADTYWCMSKL

TBC1D22A

356

Q8WUA7
QKYSLMQCWQLLALC

PLEKHH1

911

Q9ULM0
MYSVLQLLKCLCSCW

nan

1

Q8NAQ8
LTYSRTYCCWKTKMS

ZNF804A

716

Q7Z570
WIMDRASVCKLCKYA

MYO9A

2021

B2RTY4
CEQCLSYIWLMDKAL

MYO9B

1646

Q13459
SYIWLMDKALLCSVC

MYO9B

1651

Q13459