Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A PLAG1 ELF5 ZNF721 ZNF75CP ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 NR2F2 ZFP37 ZNF286A ZNF585B	2.60e-41	1459	73	51	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A PLAG1 ELF5 ZNF721 ZNF75CP ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 NR2F2 ZFP37 ZNF286A ZNF585B	1.52e-40	1412	73	50	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 PLAG1 ZNF721 ZNF75CP ZBTB12 ZNF217 ZNF350 ZNF761 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 NR2F2 ZNF286A ZNF585B	1.44e-34	1244	73	44	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 PLAG1 ZNF721 ZNF75CP ZBTB12 ZNF217 ZNF350 ZNF761 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 NR2F2 ZNF286A ZNF585B	3.61e-34	1271	73	44	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF600 ZNF585A ZNF473 ZSCAN21 ZNF341 ZNF521 ZNF814 ZNF727 ZNF778 PLAG1 ELF5 ZNF721 ZNF85 ZNF841 ZNF91 ZNF606 ZNF319 ZNF585B	1.38e-12	566	73	18	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF600 ZNF585A ZNF473 ZSCAN21 ZNF521 ZNF814 ZNF727 ZNF778 PLAG1 ELF5 ZNF721 ZNF85 ZNF841 ZNF91 ZNF606 ZNF319 ZNF585B	1.33e-11	560	73	17	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF22 ZNF727 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF85 ZNF91 PRDM5	2.46e-06	320	73	9	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF22 ZNF727 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF85 ZNF91 PRDM5	2.86e-06	326	73	9	GO:0001217
GeneOntologyMolecularFunction	tRNA-4-demethylwyosine synthase activity	TYW1B TYW1	1.32e-05	2	73	2	GO:0102521
GeneOntologyMolecularFunction	oxo-acid-lyase activity	TYW1B TYW1	2.74e-04	7	73	2	GO:0016833
GeneOntologyMolecularFunction	methyltransferase activity	KMT2C EED KMT5B PRDM5 PRDM14	1.10e-03	213	73	5	GO:0008168
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	KMT2C EED KMT5B PRDM5 PRDM14	1.37e-03	224	73	5	GO:0016741
GeneOntologyMolecularFunction	FMN binding	TYW1B TYW1	1.53e-03	16	73	2	GO:0010181
GeneOntologyMolecularFunction	histone methyltransferase activity	KMT2C EED KMT5B	2.24e-03	71	73	3	GO:0042054
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	KMT2C ZNF600 ZNF585A ZNF473 ZSCAN21 ZNF521 ZNF814 ZNF407 PLAG1 ELF5 ZNF721 ZNF841 ZNF91 ZNF606 ZNF319 PRDM5 NR2F2 ZNF585B	1.15e-06	1390	73	18	GO:0045944
Domain	-	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	9.50e-54	679	72	49	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	2.83e-53	694	72	49	IPR013087
Domain	zf-C2H2	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	1.50e-51	693	72	48	PF00096
Domain	ZINC_FINGER_C2H2_2	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	6.87e-51	775	72	49	PS50157
Domain	ZINC_FINGER_C2H2_1	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	7.81e-51	777	72	49	PS00028
Domain	Znf_C2H2-like	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	2.59e-50	796	72	49	IPR015880
Domain	Znf_C2H2	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	4.51e-50	805	72	49	IPR007087
Domain	ZnF_C2H2	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	5.43e-50	808	72	49	SM00355
Domain	zf-C2H2_6	ZNF526 ZNF600 ZNF320 ZNF486 ZNF562 ZNF560 ZNF473 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF721 ZNF761 ZNF860 ZNF85 ZNF841 ZNF91 ZNF625 ZNF606 ZNF236 ZNF626 PRDM5 ZFP37 ZNF286A	2.40e-31	314	72	28	PF13912
Domain	KRAB	ZNF132 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZNF41 ZNF253 ZNF283 ZNF611 ZNF814 ZNF727 ZNF778 ZNF75A ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF91 ZNF606 ZNF626 ZFP37 ZNF286A ZNF585B	9.97e-30	358	72	28	PS50805
Domain	KRAB	ZNF132 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZNF41 ZNF253 ZNF283 ZNF611 ZNF814 ZNF727 ZNF778 ZNF75A ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF91 ZNF606 ZNF626 ZFP37 ZNF286A ZNF585B	9.97e-30	358	72	28	PF01352
Domain	KRAB	ZNF132 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZNF41 ZNF253 ZNF283 ZNF611 ZNF814 ZNF727 ZNF778 ZNF75A ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF91 ZNF606 ZNF626 ZFP37 ZNF286A ZNF585B	2.35e-29	369	72	28	SM00349
Domain	KRAB	ZNF132 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZNF41 ZNF253 ZNF283 ZNF611 ZNF814 ZNF727 ZNF778 ZNF75A ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF91 ZNF606 ZNF626 ZFP37 ZNF286A ZNF585B	2.53e-29	370	72	28	IPR001909
Domain	Wyosine_form	TYW1B TYW1	1.47e-05	2	72	2	PF08608
Domain	tRNA_wybutosine-synth	TYW1B TYW1	1.47e-05	2	72	2	IPR013917
Domain	SET	KMT2C KMT5B PRDM5 PRDM14	1.85e-05	41	72	4	PF00856
Domain	zf-H2C2_2	ZNF778 ZNF319 ZNF286A	1.94e-05	14	72	3	PF13465
Domain	SET	KMT2C KMT5B PRDM5 PRDM14	2.93e-05	46	72	4	SM00317
Domain	SET_dom	KMT2C KMT5B PRDM5 PRDM14	4.09e-05	50	72	4	IPR001214
Domain	SET	KMT2C KMT5B PRDM5 PRDM14	4.09e-05	50	72	4	PS50280
Domain	Flavdoxin-like	TYW1B TYW1	4.04e-04	8	72	2	IPR001094
Domain	FLAVODOXIN_LIKE	TYW1B TYW1	4.04e-04	8	72	2	PS50902
Domain	Flavodoxin_1	TYW1B TYW1	4.04e-04	8	72	2	PF00258
Domain	Flavodoxin/NO_synth	TYW1B TYW1	4.04e-04	8	72	2	IPR008254
Domain	rSAM	TYW1B TYW1	5.18e-04	9	72	2	IPR007197
Domain	Radical_SAM	TYW1B TYW1	5.18e-04	9	72	2	PF04055
Domain	Flavoprotein-like_dom	TYW1B TYW1	6.46e-04	10	72	2	IPR029039
Domain	-	TYW1B TYW1	6.46e-04	10	72	2	3.40.50.360
Domain	SCAN	ZSCAN29 ZSCAN21 ZNF165	1.32e-03	56	72	3	SM00431
Domain	SCAN_BOX	ZSCAN29 ZSCAN21 ZNF165	1.46e-03	58	72	3	PS50804
Domain	SCAN	ZSCAN29 ZSCAN21 ZNF165	1.46e-03	58	72	3	PF02023
Domain	SCAN_dom	ZSCAN29 ZSCAN21 ZNF165	1.46e-03	58	72	3	IPR003309
Domain	Retrov_capsid_C	ZSCAN29 ZSCAN21 ZNF165	1.53e-03	59	72	3	IPR008916
Domain	4_helix_cytokine-like_core	ZNF547 ZNF85 ZNF236	2.93e-03	74	72	3	IPR009079
Domain	C2H2_Znf_fam	ZSCAN29 PLAG1	3.83e-03	24	72	2	IPR027775
Domain	Spectrin/alpha-actinin	AKAP6 TRIO	6.75e-03	32	72	2	IPR018159
Domain	SPEC	AKAP6 TRIO	6.75e-03	32	72	2	SM00150
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	KMT2C ZNF138 ZNF600 ZNF320 EED ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZNF41 ZNF253 ZNF611 ZNF521 ZNF727 ZNF778 ZNF75A BIRC5 ZNF721 ZNF350 ZNF761 ZNF860 ZNF772 ZNF625 ZNF664 ZNF606 ZNF626 INTS8 ZFP37 ZNF286A ZNF585B	7.62e-20	1387	52	32	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	EED ZNF585A ZNF473 ZNF814 ZNF727 ZNF778 ZNF721 ZNF85 ZNF91 ZNF664 ZNF606 ZFP37 ZNF286A ZNF585B	4.60e-07	768	52	14	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	EED ZNF585A ZNF473 ZNF814 ZNF727 ZNF778 ZNF721 ZNF85 ZNF91 ZNF664 ZNF606 INTS8 ZFP37 ZNF286A ZNF585B	2.54e-06	1022	52	15	MM15436
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF22 ZNF320 ZNF486 ZNF562 ZNF41 ZNF253 ZNF611 ZNF778 ZNF721 ZNF57 ZNF841 ZNF91 ZNF626	8.72e-17	181	73	13	37372979
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF585A ZNF814 ZNF727 ZNF778 ZNF721 ZNF85 ZNF91 ZNF585B	1.07e-13	49	73	8	9630514
Pubmed	Specific and ubiquitous expression of different Zn finger protein genes in the mouse.	ZNF585A ZNF814 ZNF778 ZNF585B	6.22e-10	7	73	4	3143103
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF727 ZNF721 ZNF85 ZNF91 ZNF626	4.05e-09	29	73	5	14563677
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF473 ZSCAN21 PLAG1 ZNF721 ZNF91 ZNF236 ZNF626 PRDM5 NR2F2 ZFP37 ZNF286A	9.55e-07	808	73	11	20412781
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KMT2C ZNF585A ZSCAN21 ZNF521 BIRC5 PLAG1 ELF5 ZNF217 NR2F2 ZNF585B	2.27e-06	709	73	10	22988430
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 KMT2C ZNF600 ZNF473 TYW1B ZSCAN21 ZNF341 DTL TYW1 ZFYVE1 ZFP37 TIAM2	2.52e-06	1084	73	12	11544199
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	4.35e-06	2	73	2	37668106
Pubmed	Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.	TYW1B TYW1	4.35e-06	2	73	2	16162496
Pubmed	Incorporating Functional Information in Tests of Excess De Novo Mutational Load.	TRIO KMT5B	4.35e-06	2	73	2	26235986
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	EED ZNF473 ZSCAN21 ZNF41 ZNF407 ELF5 ZNF236 PRDM5 PRDM14 NR2F2	1.46e-05	877	73	10	20211142
Pubmed	A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming.	EED PRDM14	2.60e-05	4	73	2	23280602
Pubmed	Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis.	TYW1B TYW1	2.60e-05	4	73	2	17150819
Pubmed	The ZNF75 zinc finger gene subfamily: isolation and mapping of the four members in humans and great apes.	ZNF75A ZNF75CP	2.60e-05	4	73	2	8661144
Pubmed	The human genome contains hundreds of genes coding for finger proteins of the Krüppel type.	ZNF85 ZNF91	6.48e-05	6	73	2	2505992
Pubmed	The yin-yang of PR-domain family genes in tumorigenesis.	PRDM5 PRDM14	9.06e-05	7	73	2	10668202
Pubmed	Mice lacking DCAF2 in placenta die at the gastrulation stage.	DTL ELF5	9.06e-05	7	73	2	35711069
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KMT2C EED PRDM14	1.10e-04	44	73	3	24183668
Pubmed	SET domains and histone methylation.	PRDM5 PRDM14	1.21e-04	8	73	2	14675547
Pubmed	The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.	ZNF85 ZNF91	1.21e-04	8	73	2	2023909
Pubmed	Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.	ZNF350 ZNF91	1.55e-04	9	73	2	23665872
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF721 ZNF91	1.93e-04	10	73	2	18588511
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF22 ZNF320 ZNF473 ZNF283 ZNF407 ZNF664 ZNF319 INTS8 ZFP37 ZNF286A	2.03e-04	1203	73	10	29180619
Pubmed	Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.	ZNF521 ADAMTS20	2.36e-04	11	73	2	22379998
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF721 ZNF91	2.36e-04	11	73	2	15469996
Pubmed	Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.	ZNF814 ZNF778 ZFP37	2.79e-04	60	73	3	18023262
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	AKAP6 TRIO ZNF91 TIAM2	2.94e-04	151	73	4	17043677
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF721 ZNF91	3.34e-04	13	73	2	19850934
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	ZNF138 ZSCAN21 ZNF91 ZNF606 ZNF319 ZNF236	3.76e-04	451	73	6	36168627
Pubmed	Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.	ZNF22 ZSCAN21	3.89e-04	14	73	2	2014798
Pubmed	Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.	KMT2C KMT5B	4.48e-04	15	73	2	35907431
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF721 ZNF91	4.48e-04	15	73	2	15885501
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF85 ZNF91	5.12e-04	16	73	2	8467795
Pubmed	Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.	ZNF407 ZNF236	5.79e-04	17	73	2	19690890
Pubmed	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.	ZNF132 ZNF138	5.79e-04	17	73	2	7557990
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF585A ZNF625 ZNF585B	7.23e-04	83	73	3	20562864
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF814 ZNF778	8.06e-04	20	73	2	2542606
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF814 ZNF778	8.06e-04	20	73	2	7479878
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF22 ZNF57	9.77e-04	22	73	2	1946370
Pubmed	Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.	PRDM5 PRDM14	9.77e-04	22	73	2	19050759
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	ZNF22 ZNF57	9.77e-04	22	73	2	1505991
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	KMT2C ZNF138 ZNF526 ZNF320	1.15e-03	217	73	4	34048709
Pubmed	CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.	EED DTL	1.59e-03	28	73	2	17041588
Pubmed	PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.	EED ZNF217	1.94e-03	31	73	2	29846670
Interaction	LTBP2 interactions	ZNF526 ZNF320 ZSCAN21 ZNF611 ZNF778 ZNF57 ZNF664	1.79e-08	85	70	7	int:LTBP2
Interaction	TRIM41 interactions	ZNF138 ZNF526 ZNF562 ZNF473 ZSCAN21 ZNF165 ZNF319 PRDM14 ZNF286A	7.66e-08	223	70	9	int:TRIM41
Interaction	TRIM28 interactions	ZNF22 ZNF600 ZNF320 EED ZNF486 ZNF562 ZNF41 ZNF253 ZNF611 ZNF778 ZNF721 ZNF350 ZNF761 ZNF57 ZNF85 ZNF841 ZNF91 ZNF626 ZNF585B	4.04e-07	1474	70	19	int:TRIM28
Interaction	ZFAT interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	2.57e-06	28	70	4	int:ZFAT
Interaction	ZNF710 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	3.42e-06	30	70	4	int:ZNF710
Interaction	GPATCH2L interactions	ZNF526 ZNF547 ZNF473 ZNF165 PRDM14	5.11e-06	72	70	5	int:GPATCH2L
Interaction	ZNF423 interactions	ZNF473 ZSCAN21 ZNF521 PRDM5 ZFP37	5.47e-06	73	70	5	int:ZNF423
Interaction	ZNF652 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	6.44e-06	35	70	4	int:ZNF652
Interaction	ZFP28 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	8.08e-06	37	70	4	int:ZFP28
Interaction	SALL4 interactions	EED ZNF473 ZSCAN21 ELF5 ZFP37	1.03e-05	83	70	5	int:SALL4
Interaction	NOTCH2 interactions	ZNF526 ZNF320 ZSCAN21 ZNF341 ZNF253 ZNF611 ZNF407 ZNF761 ZNF664	1.52e-05	423	70	9	int:NOTCH2
Interaction	KRTAP10-9 interactions	ZNF473 ZSCAN21 ZNF165 ZNF860 ZNF625 ZNF319 ZNF286A	2.02e-05	241	70	7	int:KRTAP10-9
Interaction	ZFP37 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	2.51e-05	49	70	4	int:ZFP37
Interaction	PRDM4 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	3.19e-05	52	70	4	int:PRDM4
Interaction	ZNF667 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	3.44e-05	53	70	4	int:ZNF667
Interaction	ZNF287 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	5.62e-05	60	70	4	int:ZNF287
Interaction	KRTAP10-7 interactions	ZNF138 ZNF320 ZSCAN21 ZNF165 ZNF41 ZNF778 ZNF625	7.00e-05	293	70	7	int:KRTAP10-7
Interaction	ZNF250 interactions	ZNF547 ZNF473 ZNF165 ZNF57 PRDM14	7.71e-05	126	70	5	int:ZNF250
Interaction	ZSCAN10 interactions	ZNF473 ZSCAN21 ZFP37	9.85e-05	26	70	3	int:ZSCAN10
Interaction	ZFP3 interactions	ZNF473 ZSCAN21 ZFP37	1.52e-04	30	70	3	int:ZFP3
Interaction	ZNF837 interactions	ZNF526 ZNF473 ZSCAN21 ZNF165	1.65e-04	79	70	4	int:ZNF837
Interaction	ZNF382 interactions	ZNF473 ZSCAN21 ZFP37	2.03e-04	33	70	3	int:ZNF382
Interaction	ZNF513 interactions	ZNF473 ZSCAN21 ZFP37	2.22e-04	34	70	3	int:ZNF513
Interaction	ZFP62 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	3.92e-04	99	70	4	int:ZFP62
Interaction	ZNF467 interactions	ZNF22 ZNF320 ZSCAN21 ZNF721 ZNF761	3.97e-04	179	70	5	int:ZNF467
Interaction	GZF1 interactions	ZNF473 ZSCAN21 PRDM5 ZFP37	4.55e-04	103	70	4	int:GZF1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF132 ZNF526 ZNF600 ZNF320 ZNF547 ZNF585A ZNF473 ZNF283 ZNF611 ZNF814 ZNF350 ZNF761 ZNF772 ZNF841 ZNF606 ZNF585B	5.08e-11	1192	73	16	chr19q13
Cytoband	19q13.41	ZNF600 ZNF320 ZNF611 ZNF350 ZNF841	1.71e-07	78	73	5	19q13.41
Cytoband	19p12	ZNF486 ZNF85 ZNF91 ZNF626	1.36e-05	90	73	4	19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF486 ZNF85 ZNF91 ZNF626	4.48e-05	122	73	4	chr19p12
Cytoband	7q11.21	ZNF138 ZNF727 TYW1	3.23e-04	83	73	3	7q11.21
Cytoband	19q13.43	ZNF547 ZNF814 ZNF772	3.71e-04	87	73	3	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	ZNF138 TYW1B ZNF727 TYW1	9.39e-04	271	73	4	chr7q11
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	IZUMO4 ZNF562 ZNF560 ZNF253 ZNF57 ZNF625	1.71e-03	797	73	6	chr19p13
Cytoband	Ensembl 112 genes in cytogenetic band chr18q22	RTTN ZNF407	5.16e-03	67	73	2	chr18q22
Cytoband	19p13.2	ZNF562 ZNF560 ZNF625	5.89e-03	229	73	3	19p13.2
Cytoband	19q13.12	ZNF585A ZNF585B	5.93e-03	72	73	2	19q13.12
Cytoband	19q13.4	ZNF132 ZNF606	7.10e-03	79	73	2	19q13.4
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZSCAN29 ZNF132 ZNF138 ZNF22 ZNF526 ZNF600 ZNF320 ZNF547 ZNF486 ZNF585A ZNF562 ZNF560 ZNF473 ZSCAN21 ZNF165 ZNF341 ZNF41 ZNF253 ZNF283 ZNF611 ZNF521 ZNF814 ZNF727 ZNF778 ZNF75A ZNF407 PLAG1 ZNF721 ZBTB12 ZNF217 ZNF350 ZNF761 ZNF57 ZNF860 ZNF772 ZNF85 ZNF841 ZNF91 ZNF625 ZNF664 ZNF606 ZNF319 ZNF236 ZNF626 PRDM5 PRDM14 ZFP37 ZNF286A ZNF585B	7.37e-54	718	68	49	28
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM5 PRDM14	1.83e-03	17	68	2	1197
ToppCell	343B-Lymphocytic-ILC\|343B / Donor, Lineage, Cell class and subclass (all cells)	ZNF547 ZNF814 DGKH ZNF217 ZNF625	7.89e-06	166	73	5	a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	ZNF138 ZNF41 ZNF253 ZNF814 BIRC5	9.92e-06	174	73	5	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF600 RTTN CACNA1I DGKH HELB	1.80e-05	197	73	5	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF547 ZNF253 ZNF814 ZNF727 ZNF319	1.80e-05	197	73	5	fd76cc5e12c7e7943a48f739e4f0626ff7211f51
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KMT2C TRIO DTL ZNF521 DGKH	1.94e-05	200	73	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
Computational	Genes in the cancer module 205.	SPOCK1 DTL ZNF350 INTS8 TIAM2 ZNF286A	1.10e-04	305	28	6	MODULE_205
Disease	body weight	AKAP6 SPOCK1 ZNF341 RTTN DTL ZNF521 PLAG1 DGKH PRDM5 ZFYVE1	4.68e-04	1261	66	10	EFO_0004338
Disease	thyroxine measurement, triiodothyronine measurement	ZNF841 TIAM2	6.56e-04	17	66	2	EFO_0005130, EFO_0008392
Disease	Neurodevelopmental Disorders	KMT2C TRIO KMT5B	1.20e-03	93	66	3	C1535926
Disease	Intellectual Disability	AKAP6 KMT2C ZNF526 TRIO RTTN	3.27e-03	447	66	5	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
CAKCEHKTSVGVHSF	USP26	496	Q9BXU7
ECGKAFSHCSSLTKH	ZNF286A	386	Q9HBT8
EHKKHSSGCAFLSVK	BIRC5	76	O15392
CKGHQCSLKSVAFSK	DTL	136	Q9NZJ0
CLKTSGIKSQDCHSH	ELF5	151	Q9UKW6
CTSTEKLHKGCFTQH	ADAMTS20	511	P59510
HIECVVCGDKSSGKH	NR2F2	76	P24468
KGLHCSTVKDFSHAK	INTS8	576	Q75QN2
TFKCHHCDATFKRKD	PRDM5	431	Q9NQX1
KCVFCHKTGATSGCH	KMT2C	4461	Q8NEZ4
AHETAQKGEAKCHKS	KMT5B	591	Q4FZB7
PHKAKCTTLTHHKCG	EED	396	O75530
SHGLSCEVCKFKAHK	DGKH	201	Q86XP1
HYSSPAGCKKCHHDK	CACNA1I	1831	Q9P0X4
HGCLHCHSNFSKKFS	IZUMO4	16	Q1ZYL8
CCKHYTGHLTKDHQS	HELB	756	Q8NG08
AKGHLQAKSKTHLCC	RTTN	1806	Q86VV8
CCSASSGESKAHIKK	USH2A	3336	O75445
EKHRPHKCSTCGKCF	PRDM14	456	Q9GZV8
GSHGKEISESEHCKC	AKAP6	1921	Q13023
SSGGVKEKKHQCEHC	PLAG1	176	Q6DJT9
CHKAFRCCSDLTKHK	ZNF727	261	A8MUV8
HVCKECGKAFSHSSK	ZNF132	291	P52740
SAHAKTHKGEKSFEC	ZNF562	276	Q6V9R5
HKCTECGKAFTRSTH	ZNF562	316	Q6V9R5
SHSGMKLHKCALCSK	ZNF341	676	Q9BYN7
ECGKTFSHKSSLTCH	ZNF761	386	Q86XN6
CGKSFKNSSCLNHHT	ZNF778	706	Q96MU6
ICGKCFTQKSTLHDH	ZBTB12	391	Q9Y330
CKVCDKAFKHDSHLA	ZNF320	191	A2RRD8
CHHCGKTFCSKSNLS	ZSCAN21	446	Q9Y5A6
CAHCGKAFKQSSHLT	ZNF138	196	P52744
HSACASLFAKKHGKE	TIAM2	616	Q8IVF5
KLHTGDKKYHCSECD	ZNF521	166	Q96K83
FKCHECGKIFIHKSN	ZNF75CP	376	Q92670
HTGEKHFKCNECGKS	ZNF721	91	Q8TF20
CKECGKAFMHSSHLN	ZNF721	211	Q8TF20
TSKCKLEFHACSTGK	SPOCK1	156	Q08629
HHECTDCGKAFTQKS	ZNF585B	241	Q52M93
HHECTDCGKAFTQKS	ZNF585A	241	Q6P3V2
KCATSFKDNDTKHHC	ZFYVE1	606	Q9HBF4
KLEKHHVCSECGKAF	ZNF350	201	Q9GZX5
CGKAFNHSCSLTRHK	ZNF626	206	Q68DY1
KPHKCSECGRTFSHK	ZNF841	591	Q6ZN19
CGKAFKHSSALAKHK	ZNF91	831	Q05481
ECGKSFKHCSNLTIH	ZNF253	316	O75346
HSSHSGLVKCSICEK	ZNF319	151	Q9P2F9
CSDCGKSFTKKSQLH	ZNF41	511	P51814
FLCSECGKAFSHKHK	ZNF547	156	Q8IVP9
HKCDKCDKGFFHISE	ZNF664	31	Q8N3J9
IHTGKKSHKCADCGK	ZNF22	76	P17026
KSHKCADCGKSFFQS	ZNF22	81	P17026
FTHQKSCKHGTCDQS	ZNF165	286	P49910
QLHKCEHCGKAFTSS	ZNF57	446	Q68EA5
KSHEKTHTGVKAFSC	ZNF236	1011	Q9UL36
DCHVKTHTGQKLFSC	ZNF236	1211	Q9UL36
CAGLSQEKEKCKHSH	ZNF217	341	O75362
THECTTCSKVFKKAA	ZNF526	331	Q8TF50
CGKTFSHKSSLVCHH	ZNF611	431	Q8N823
KCEKCGKAFNHFSHL	ZNF85	371	Q03923
EKHHKCDDCGKAFTS	ZNF860	591	A6NHJ4
CGKAFHSSTCLHAHK	ZNF625	186	Q96I27
HTGSKPFKCKICHFA	ZNF407	1561	Q9C0G0
CKKGKCESHQHGSEE	TYW1	256	Q9NV66
TCHECGKKFSQNSHL	ZNF75A	246	Q96N20
HDCGKCFSKSSALNK	ZSCAN29	821	Q8IWY8
HTGEKSYKCTVCDKA	ZNF600	576	Q6ZNG1
HFKKGCESVDECKLH	ZNF486	121	Q96H40
HSSSDKCNKTGKKHD	ZFP37	236	Q9Y6Q3
GKKHDKLCCHSSSHI	ZFP37	246	Q9Y6Q3
SNTKCEEASHCGKRH	ZNF772	251	Q68DY9
CGGHCKKGKCESHQH	TYW1B	206	Q6NUM6
FCEKGHAHAAEIKKC	TRIO	1206	O75962
HTEKKHECGECGKSF	ZNF814	291	B7Z6K7
HAREKTFKCDHCGKA	ZNF560	426	Q96MR9
KCGKSFSQSCHLVAH	ZNF606	656	Q8WXB4
FKCNECGKTFSHSAH	ZNF473	646	Q8WTR7
HTGEKSHECKECGKT	ZNF283	481	Q8N7M2