Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	promoter-specific chromatin binding	SUZ12 L3MBTL2 HNRNPU	4.48e-04	83	36	3	GO:1990841
GeneOntologyMolecularFunction	methylated histone binding	MSH6 SUZ12 L3MBTL2	4.97e-04	86	36	3	GO:0035064
GeneOntologyMolecularFunction	modification-dependent protein binding	MSH6 SUZ12 L3MBTL2 BAZ2A	5.00e-04	206	36	4	GO:0140030
GeneOntologyMolecularFunction	methylation-dependent protein binding	MSH6 SUZ12 L3MBTL2	5.32e-04	88	36	3	GO:0140034
GeneOntologyMolecularFunction	poly(A) binding	KHDRBS1 HNRNPU	1.24e-03	29	36	2	GO:0008143
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH3 MYH13 DNAH8	1.25e-03	118	36	3	GO:0003774
GeneOntologyMolecularFunction	histone binding	MSH6 SUZ12 L3MBTL2 BAZ2A	1.28e-03	265	36	4	GO:0042393
GeneOntologyMolecularFunction	lncRNA binding	SUZ12 HNRNPU	1.81e-03	35	36	2	GO:0106222
GeneOntologyMolecularFunction	poly-purine tract binding	KHDRBS1 HNRNPU	2.02e-03	37	36	2	GO:0070717
GeneOntologyMolecularFunction	microfilament motor activity	MYH3 MYH13	2.13e-03	38	36	2	GO:0000146
GeneOntologyMolecularFunction	poly-pyrimidine tract binding	KHDRBS1 HNRNPU	2.25e-03	39	36	2	GO:0008187
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIFAP3 MYH3 DLC1 MYH13 MAP3K1 HNRNPU SMTN	3.07e-03	1099	36	7	GO:0008092
GeneOntologyMolecularFunction	SH2 domain binding	DLC1 KHDRBS1	3.96e-03	52	36	2	GO:0042169
GeneOntologyMolecularFunction	ATP-dependent activity	MSH6 MYH3 MYH13 DNAH8 ATP2B2	4.63e-03	614	36	5	GO:0140657
GeneOntologyCellularComponent	chromatin silencing complex	SUZ12 BAZ2A	2.74e-04	14	37	2	GO:0005677
GeneOntologyCellularComponent	muscle myosin complex	MYH3 MYH13	3.60e-04	16	37	2	GO:0005859
GeneOntologyCellularComponent	supramolecular fiber	KIFAP3 MYH3 DLC1 MYH13 DNAH8 MAP3K1 HNRNPU SMTN	8.91e-04	1179	37	8	GO:0099512
GeneOntologyCellularComponent	myosin filament	MYH3 MYH13	8.91e-04	25	37	2	GO:0032982
GeneOntologyCellularComponent	nuclear body	PRPF6 AMER1 SUZ12 SKIL CCNB3 BAZ2A HNRNPU	9.07e-04	903	37	7	GO:0016604
GeneOntologyCellularComponent	supramolecular polymer	KIFAP3 MYH3 DLC1 MYH13 DNAH8 MAP3K1 HNRNPU SMTN	9.31e-04	1187	37	8	GO:0099081
GeneOntologyCellularComponent	myosin II complex	MYH3 MYH13	1.12e-03	28	37	2	GO:0016460
GeneOntologyCellularComponent	filamentous actin	MAP3K1 SMTN	2.06e-03	38	37	2	GO:0031941
GeneOntologyCellularComponent	actin filament	DLC1 MAP3K1 SMTN	2.18e-03	146	37	3	GO:0005884
GeneOntologyCellularComponent	nuclear protein-containing complex	MSH6 PRPF6 SUZ12 BAZ2A TSEN2 NUP35 HNRNPU BACH1	2.41e-03	1377	37	8	GO:0140513
GeneOntologyCellularComponent	sex chromosome	SUZ12 HNRNPU	2.75e-03	44	37	2	GO:0000803
GeneOntologyCellularComponent	actin cytoskeleton	MYH3 DLC1 MYH13 MAP3K1 SMTN	3.28e-03	576	37	5	GO:0015629
Domain	Myosin_N	MYH3 MYH13	3.73e-04	15	36	2	PF02736
Domain	Myosin_N	MYH3 MYH13	3.73e-04	15	36	2	IPR004009
Domain	Myosin_tail_1	MYH3 MYH13	5.42e-04	18	36	2	PF01576
Domain	Myosin_tail	MYH3 MYH13	5.42e-04	18	36	2	IPR002928
Domain	Myosin-like_IQ_dom	MYH3 MYH13	6.05e-04	19	36	2	IPR027401
Domain	-	MYH3 MYH13	6.05e-04	19	36	2	4.10.270.10
Domain	SPRY	HNRNPUL1 HERC1 HNRNPU	6.24e-04	87	36	3	SM00449
Domain	-	HNRNPUL1 HNRNPU	7.41e-04	21	36	2	1.10.720.30
Domain	SPRY	HNRNPUL1 HERC1 HNRNPU	7.82e-04	94	36	3	PF00622
Domain	SPRY_dom	HNRNPUL1 HERC1 HNRNPU	7.82e-04	94	36	3	IPR003877
Domain	B30.2/SPRY	HNRNPUL1 HERC1 HNRNPU	8.06e-04	95	36	3	IPR001870
Domain	B302_SPRY	HNRNPUL1 HERC1 HNRNPU	8.06e-04	95	36	3	PS50188
Domain	SAP	HNRNPUL1 HNRNPU	8.14e-04	22	36	2	PF02037
Domain	SAP	HNRNPUL1 HNRNPU	8.91e-04	23	36	2	SM00513
Domain	SAP	HNRNPUL1 HNRNPU	1.05e-03	25	36	2	PS50800
Domain	SAP_dom	HNRNPUL1 HNRNPU	1.05e-03	25	36	2	IPR003034
Domain	Myosin_head_motor_dom	MYH3 MYH13	2.43e-03	38	36	2	IPR001609
Domain	MYOSIN_MOTOR	MYH3 MYH13	2.43e-03	38	36	2	PS51456
Domain	Myosin_head	MYH3 MYH13	2.43e-03	38	36	2	PF00063
Domain	MYSc	MYH3 MYH13	2.43e-03	38	36	2	SM00242
Domain	P-loop_NTPase	MSH6 MYH3 HNRNPUL1 MYH13 DNAH8 HNRNPU	5.22e-03	848	36	6	IPR027417
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	KIFAP3 MSH6 PRPF6 KARS1 AMER1 HNRNPUL1 KHDRBS1 BAZ2A HNRNPU	1.32e-07	809	37	9	32129710
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TRPM6 MSH6 PRPF6 KARS1 SUZ12 HNRNPUL1 KHDRBS1 TTC3 NUP35 HNRNPU KIAA0586	1.68e-07	1425	37	11	30948266
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRPF6 KARS1 SUZ12 HNRNPUL1 KHDRBS1 SKIL L3MBTL2 BAZ2A HNRNPU BACH1	6.83e-07	1294	37	10	30804502
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH3 PRPF6 AMER1 MYH13 KHDRBS1 TTC3 DNAH8 ATP2B2 NUP35 HNRNPU	1.82e-06	1442	37	10	35575683
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	AMER1 SUZ12 HNRNPUL1 KHDRBS1 HNRNPU	4.63e-06	232	37	5	25515538
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	PRPF6 HNRNPUL1 KHDRBS1 HNRNPU	5.57e-06	109	37	4	29511296
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	MSH6 PRPF6 HNRNPUL1 KHDRBS1 HNRNPU	5.92e-06	244	37	5	29884807
Pubmed	The human SWI/SNF subunit Brm is a regulator of alternative splicing.	PRPF6 KHDRBS1	6.60e-06	4	37	2	16341228
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	MSH6 KHDRBS1 L3MBTL2 HNRNPU	7.13e-06	116	37	4	21549307
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	KIFAP3 TMED1 PRPF6 KARS1 AMER1 HNRNPUL1 ATP2B2 EIF2B3 BACH1	7.61e-06	1321	37	9	27173435
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MSH6 PRPF6 KARS1 KHDRBS1 DNAH8 NUP35 HNRNPU	8.20e-06	704	37	7	29955894
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MSH6 PRPF6 KARS1 HNRNPUL1 L3MBTL2 BAZ2A HNRNPU EIF2B3 SMTN	9.23e-06	1353	37	9	29467282
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MSH6 PRPF6 KARS1 SUZ12 HNRNPUL1 MAP3K1 HNRNPU	1.33e-05	759	37	7	35915203
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ZBTB40 MSH6 SUZ12 HNRNPUL1 BAZ2A BACH1 SMTN	1.51e-05	774	37	7	15302935
Pubmed	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.	MYH3 MYH13	1.65e-05	6	37	2	10077619
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZBTB40 MSH6 PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU BACH1	1.70e-05	1103	37	8	34189442
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH3 MYH13	2.30e-05	7	37	2	35210422
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	PRPF6 KARS1 HNRNPUL1 KHDRBS1 L3MBTL2 HNRNPU	2.36e-05	551	37	6	34728620
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RTKN2 PRPF6 HNRNPUL1 L3MBTL2 TSEN2 HNRNPU BACH1 SMTN	2.36e-05	1155	37	8	20360068
Pubmed	Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells.	SUZ12 BACH1	3.07e-05	8	37	2	30891497
Pubmed	The Deubiquitinase USP39 Promotes Esophageal Squamous Cell Carcinoma Malignancy as a Splicing Factor.	PRPF6 HNRNPU	3.07e-05	8	37	2	35627203
Pubmed	Functional proteomics mapping of a human signaling pathway.	TMED1 HNRNPUL1 HERC1 KHDRBS1 SKIL TTC3	3.49e-05	591	37	6	15231748
Pubmed	MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.	AMER1 MAP3K1	3.95e-05	9	37	2	20128690
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	PRPF6 HNRNPUL1 KHDRBS1 HNRNPU	5.70e-05	197	37	4	22365833
Pubmed	Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.	REV3L L3MBTL2 HNRNPU	6.82e-05	74	37	3	29795351
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	TMED1 MSH6 L3MBTL2 HNRNPU EIF2B3	6.94e-05	408	37	5	33766124
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	MSH6 PRPF6 KHDRBS1 BAZ2A NUP35	7.18e-05	411	37	5	35182466
Pubmed	Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN.	KHDRBS1 MAP3K1	7.22e-05	12	37	2	16888650
Pubmed	Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.	ERBB4 HNRNPU	8.53e-05	13	37	2	20858735
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	PRPF6 HNRNPUL1 KHDRBS1 HNRNPU	8.73e-05	220	37	4	34091597
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	MSH6 HERC1 HNRNPU	1.03e-04	85	37	3	16051665
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TMED1 MSH6 PRPF6 KARS1 HNRNPUL1 HNRNPU EIF2B3 SMTN	1.12e-04	1440	37	8	30833792
Pubmed	The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.	AMER1 KHDRBS1	1.15e-04	15	37	2	25882849
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	KARS1 HNRNPUL1 KHDRBS1 TTC3 HNRNPU	1.24e-04	462	37	5	31138677
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	KARS1 HERC1 KHDRBS1 HNRNPU	1.32e-04	245	37	4	35652658
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	MSH6 KARS1 KHDRBS1 HNRNPU ZNF804B	1.44e-04	477	37	5	31300519
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MSH6 ERBB4 SUZ12 REV3L SKIL CCNB3 BAZ2A	1.52e-04	1116	37	7	31753913
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	MYH3 PRPF6 KARS1 KHDRBS1	1.64e-04	259	37	4	31162944
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU	1.70e-04	494	37	5	26831064
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	MSH6 PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU EIF2B3	1.82e-04	1149	37	7	35446349
Pubmed	Comprehensive proteomic analysis of the human spliceosome.	PRPF6 HNRNPUL1 HNRNPU	2.15e-04	109	37	3	12226669
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	PRPF6 KARS1 KHDRBS1 TTC3	2.29e-04	283	37	4	18854154
Pubmed	A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.	KARS1 HNRNPUL1 KHDRBS1 HNRNPU	2.39e-04	286	37	4	32041737
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	PRPF6 HNRNPUL1 HNRNPU	2.52e-04	115	37	3	17332742
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	MSH6 KARS1 HNRNPUL1 MYH13 HNRNPU	2.98e-04	558	37	5	27591049
Pubmed	USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID.	MSH6 HNRNPU	2.99e-04	24	37	2	34983926
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	ERBB4 PRPF6 KARS1 HNRNPUL1	3.01e-04	304	37	4	32235678
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	AMER1 SUZ12 HNRNPU	3.45e-04	128	37	3	25332235
Pubmed	FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.	PRPF6 HNRNPUL1 HERC1	3.45e-04	128	37	3	28027390
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	PRPF6 KHDRBS1 L3MBTL2 BAZ2A HNRNPU	3.64e-04	583	37	5	29844126
Pubmed	Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.	MYH3 DNAH8	3.80e-04	27	37	2	18649358
Pubmed	Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.	SUZ12 BAZ2A	3.80e-04	27	37	2	19026994
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	KARS1 KHDRBS1 L3MBTL2 HNRNPU	3.97e-04	327	37	4	31409639
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	MSH6 SUZ12 HNRNPU	4.03e-04	135	37	3	31077711
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	MSH6 PRPF6 KARS1 HNRNPUL1 BAZ2A HNRNPU EIF2B3	4.19e-04	1318	37	7	30463901
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	MSH6 PRPF6 KARS1 HNRNPU	4.20e-04	332	37	4	32786267
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MSH6 KARS1 HNRNPUL1 L3MBTL2 BAZ2A HNRNPU	4.21e-04	934	37	6	33916271
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ZBTB40 MSH6 RTKN2 SUZ12 HNRNPUL1 KHDRBS1 TSEN2	4.37e-04	1327	37	7	32694731
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZBTB40 MSH6 SUZ12 L3MBTL2 BAZ2A	4.41e-04	608	37	5	36089195
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU SMTN	4.58e-04	949	37	6	36574265
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	PRPF6 HNRNPUL1 KHDRBS1 HNRNPU	4.59e-04	340	37	4	24332808
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU	4.64e-04	615	37	5	31048545
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PRPF6 KARS1 KHDRBS1 BAZ2A	4.65e-04	341	37	4	32971831
Pubmed	Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.	KHDRBS1 HNRNPU	4.70e-04	30	37	2	15782174
Pubmed	hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.	MSH6 HNRNPUL1 HNRNPU EIF2B3	4.91e-04	346	37	4	25324306
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	PRPF6 HNRNPUL1 KHDRBS1 HNRNPU SMTN	5.03e-04	626	37	5	33644029
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	TMED1 MSH6 PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU	5.22e-04	1367	37	7	32687490
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	MSH6 SUZ12 BAZ2A	5.49e-04	150	37	3	28242625
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	MSH6 PRPF6 KARS1 KHDRBS1 HNRNPU	5.60e-04	641	37	5	36057605
Pubmed	Lynch Syndrome	MSH6 DLC1	5.69e-04	33	37	2	20301390
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MSH6 PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU	5.70e-04	989	37	6	36424410
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	HNRNPUL1 KHDRBS1 HNRNPU	5.92e-04	154	37	3	16055720
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MSH6 PRPF6 KARS1 HNRNPUL1 BAZ2A	6.09e-04	653	37	5	22586326
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	MSH6 PRPF6 KARS1 HNRNPUL1 HNRNPU	6.18e-04	655	37	5	35819319
Pubmed	Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.	KARS1 HNRNPU	6.78e-04	36	37	2	24147044
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	MSH6 PRPF6 KHDRBS1 HNRNPU	7.17e-04	383	37	4	29331416
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	KARS1 HNRNPUL1 KHDRBS1	7.36e-04	166	37	3	35687106
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	MSH6 KARS1 HNRNPUL1 HERC1 TSEN2 HNRNPU EIF2B3	7.55e-04	1455	37	7	22863883
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	PRPF6 HNRNPUL1 KHDRBS1 HNRNPU	7.68e-04	390	37	4	17643375
Pubmed	Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.	HNRNPUL1 HNRNPU	8.37e-04	40	37	2	23825951
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	HNRNPUL1 HERC1 KHDRBS1 TTC3 BAZ2A NUP35 EIF2B3	8.90e-04	1496	37	7	32877691
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	MSH6 PRPF6 HNRNPUL1 KHDRBS1 HNRNPU	9.04e-04	713	37	5	29802200
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	MSH6 PRPF6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU	9.10e-04	1082	37	6	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TRPM6 ZBTB40 AMER1 HERC1 TTC3 SMTN	9.19e-04	1084	37	6	11544199
Pubmed	Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4.	SUZ12 HNRNPU	9.67e-04	43	37	2	30026490
Pubmed	A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.	KIFAP3 KHDRBS1	1.01e-03	44	37	2	32492419
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MSH6 MYH3 KARS1 REV3L HNRNPU	1.04e-03	736	37	5	29676528
Interaction	CEBPB interactions	MSH6 PRPF6 KARS1 SUZ12 HNRNPUL1 KHDRBS1 SKIL BAZ2A NUP35 HNRNPU EIF2B3 BACH1	5.96e-06	1443	37	12	int:CEBPB
Interaction	BRCA1 interactions	MSH6 RTKN2 PRPF6 KARS1 SUZ12 HNRNPUL1 HERC1 KHDRBS1 MAP3K1 HNRNPU SMTN	9.48e-06	1249	37	11	int:BRCA1
Interaction	RBM22 interactions	KIFAP3 PRPF6 SUZ12 HNRNPUL1 NUP35	1.37e-05	169	37	5	int:RBM22
Interaction	SMARCA2 interactions	PRPF6 SUZ12 REV3L KHDRBS1 CCNB3 NUP35	3.64e-05	346	37	6	int:SMARCA2
Interaction	TRIM28 interactions	MSH6 ERBB4 PRPF6 KARS1 AMER1 SUZ12 KHDRBS1 L3MBTL2 DNAH8 NUP35 HNRNPU	4.46e-05	1474	37	11	int:TRIM28
Interaction	RUSC2 interactions	KIFAP3 MSH6 KHDRBS1	4.60e-05	38	37	3	int:RUSC2
Interaction	SMC3 interactions	KIFAP3 MSH6 PRPF6 SUZ12 L3MBTL2 HNRNPU	9.07e-05	408	37	6	int:SMC3
Interaction	BIRC3 interactions	MSH6 PRPF6 KARS1 SUZ12 HNRNPUL1 KHDRBS1 TTC3 NUP35 HNRNPU KIAA0586	1.04e-04	1334	37	10	int:BIRC3
Interaction	MUC4 interactions	ERBB4 SUZ12	1.17e-04	9	37	2	int:MUC4
Interaction	PSME1 interactions	KARS1 HNRNPUL1 KHDRBS1 TTC3 HNRNPU	1.37e-04	274	37	5	int:PSME1
Interaction	NXF3 interactions	HNRNPUL1 SKIL	1.46e-04	10	37	2	int:NXF3
GeneFamily	Myosin heavy chains	MYH3 MYH13	2.06e-04	15	26	2	1098
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB40 BACH1	1.58e-02	134	26	2	861
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB40 MYH3 RTKN2 PSAPL1	1.05e-05	165	37	4	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB40 MYH3 RTKN2 PSAPL1	1.05e-05	165	37	4	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH6 MAP3K1 HNRNPU BACH1	1.98e-05	194	37	4	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH6 MAP3K1 HNRNPU BACH1	1.98e-05	194	37	4	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KIFAP3 HERC1 TTC3 ATP2B2	1.98e-05	194	37	4	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH6 MAP3K1 HNRNPU BACH1	1.98e-05	194	37	4	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	mLN-T_cell-Treg\|T_cell / Region, Cell class and subclass	RTKN2 DNAH8 MAP3K1 BACH1	2.10e-05	197	37	4	3779489d57ebda33277c79cba037f4c73128c8ba
ToppCell	(1)_T_cell-(15)_Treg\|(1)_T_cell / shred on Cell_type and subtype	RTKN2 DNAH8 MAP3K1 BACH1	2.10e-05	197	37	4	6e7723e8b977be35c60cc11ac7cfa4f71339441e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIFAP3 HERC1 TTC3 ATP2B2	2.14e-05	198	37	4	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	SUZ12 REV3L KHDRBS1 TTC3	2.19e-05	199	37	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	KIFAP3 HERC1 TTC3 ATP2B2	2.23e-05	200	37	4	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 ZNF804B SMTN	1.31e-04	119	37	3	6425425b2e622c97b6c74c530ccbfe394d3b202d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 MYH13 ZNF804B	1.70e-04	130	37	3	60e28d452d0e2af768459ba8dbe998117c94a251
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 ZNF804B SMTN	2.12e-04	140	37	3	72c272f44e5600b3037c1dbf9d3a4669a35588d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYH3 L3MBTL2 DNAH8	2.65e-04	151	37	3	ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RTKN2 DNAH8 BACH1	2.81e-04	154	37	3	9200e2f1783e54cbc5dfc3b485b57c761af74a46
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RTKN2 DNAH8 BACH1	2.81e-04	154	37	3	b16f3139ce50e70a6a2377b1da7d7877b4000ea1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRPM6 KIFAP3 KARS1	2.91e-04	156	37	3	14e2f693a75f1075f40cc7b16ee430262a5de016
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB40 DNAH8 KIAA0586	3.37e-04	164	37	3	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB40 DNAH8 KIAA0586	3.37e-04	164	37	3	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB40 DNAH8 KIAA0586	3.37e-04	164	37	3	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	mild-Lymphocytic-CD4_T_cells_3\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RTKN2 DNAH8 MAP3K1	3.49e-04	166	37	3	f8f8423423d72f0ea0266b59126abb27beb23094
ToppCell	Control\|World / group, cell type (main and fine annotations)	RTKN2 ERBB4 DLC1	3.62e-04	168	37	3	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HNRNPUL1 BAZ2A SMTN	4.15e-04	176	37	3	29cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HNRNPUL1 BAZ2A SMTN	4.15e-04	176	37	3	01774a86d7d92f31a056b753f9844f923038003e
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH3 DNAH8 ZNF804B	4.22e-04	177	37	3	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH3 DNAH8 ZNF804B	4.22e-04	177	37	3	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	facs-Heart-RA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HNRNPUL1 SKIL HNRNPU	4.29e-04	178	37	3	b505e2550860e777535ee95f29c936242fd607f1
ToppCell	(2)_NK/T-(230)_CD4+/CD25+_Reg_T_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	RTKN2 MAP3K1 BACH1	4.50e-04	181	37	3	ad14c7111d4fb924afd233cb114447f195373a7c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RTKN2 KHDRBS1 SMTN	4.57e-04	182	37	3	f549b986caebc5eb1b2d12f34fe33087e8324a31
ToppCell	(1)_T_cells-(1)_T_regulatory\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	RTKN2 DNAH8 BACH1	4.72e-04	184	37	3	3cbf81757653652441843d85cb7ec1dcf25ca1b0
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH6 TTC3 KIAA0586	4.87e-04	186	37	3	60830822d3de3147816693404fd03392e04c2b8e
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH6 TTC3 KIAA0586	4.87e-04	186	37	3	37860daeecd6d412bd3797f30496a56da667fbd1
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH6 TTC3 KIAA0586	4.87e-04	186	37	3	baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 BACH1 SMTN	5.02e-04	188	37	3	72cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH6 MAP3K1 BACH1	5.02e-04	188	37	3	59b71462338a7efbacf46577cb07e9db3363afee
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	RTKN2 ERBB4 DLC1	5.02e-04	188	37	3	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	MS-Treg-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	RTKN2 DNAH8 BACH1	5.10e-04	189	37	3	b1310eed6113b3536868340a5b2b2587ad377fa9
ToppCell	MS-Treg\|MS / Condition, Cell_class and T cell subcluster	RTKN2 DNAH8 BACH1	5.10e-04	189	37	3	3fa79242fb3dba4a3f52276da0124ba260423fb6
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_Tregs\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RTKN2 DNAH8 BACH1	5.18e-04	190	37	3	f69a4733b5d1542ab4d0eb44856f2c5c34c18b9e
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RTKN2 KIAA0586 SMTN	5.26e-04	191	37	3	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	COPD-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	RTKN2 DNAH8 BACH1	5.26e-04	191	37	3	3ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCell	ILEUM-non-inflamed-(6)_ILC3\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RTKN2 PRPF6 SKIL	5.26e-04	191	37	3	6eaf72b41084404bee0db04e4605db745a74995f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	HERC1 SKIL MAP3K1	5.34e-04	192	37	3	aee6522d25e012231cdb905ce047295cb64d6e82
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SKIL MAP3K1	5.42e-04	193	37	3	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	KHDRBS1 MAP3K1 BACH1	5.42e-04	193	37	3	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SKIL MAP3K1	5.42e-04	193	37	3	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SKIL MAP3K1	5.42e-04	193	37	3	263d185af6ed80e639f864e4966268e0862c61dc
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RTKN2 ERBB4 DLC1	5.51e-04	194	37	3	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SKIL MAP3K1	5.59e-04	195	37	3	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SKIL MAP3K1	5.59e-04	195	37	3	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REV3L HERC1 TTC3	5.59e-04	195	37	3	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RTKN2 ERBB4 DLC1	5.59e-04	195	37	3	9406866f99555198a9be311fbd65751b70f35446
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REV3L HERC1 TTC3	5.59e-04	195	37	3	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	primary_visual_cortex-Neuronal\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KIFAP3 TTC3 ATP2B2	5.67e-04	196	37	3	8efc2b3a95f57c31be203ac781b2098d4909297f
ToppCell	frontal_cortex-Neuronal\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KIFAP3 TTC3 ATP2B2	5.67e-04	196	37	3	de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_4\|COVID-19_Mild / Disease condition and Cell class	SKIL MAP3K1 BACH1	5.67e-04	196	37	3	3729d1444c65cad640377894decc64129bc3fd5b
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SKIL TTC3 BACH1	5.67e-04	196	37	3	97ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCell	mild_COVID-19_(asymptomatic)\|World / disease group, cell group and cell class (v2)	SKIL MAP3K1 BACH1	5.67e-04	196	37	3	8cb3dcb3e5732f4bb060c87ca339b8997a1a8cd4
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RTKN2 KHDRBS1 MAP3K1	5.76e-04	197	37	3	196eaecef7003ed83f323c1f157c6a3594650097
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	SKIL HNRNPU BACH1	5.76e-04	197	37	3	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RTKN2 HERC1 HNRNPU	5.76e-04	197	37	3	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	T_cells-Treg_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	RTKN2 DNAH8 MAP3K1	5.76e-04	197	37	3	ec9398ae3577f61d6b1e6aba50ef4261aaaa7610
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS\|TCGA-Stomach / Sample_Type by Project: Shred V9	KARS1 KHDRBS1 NUP35	5.84e-04	198	37	3	08f9f05abad4e4078362ea8537c616084cb5d70a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIFAP3 TTC3 ATP2B2	5.84e-04	198	37	3	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 KIAA0586 SMTN	5.84e-04	198	37	3	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	SKIL HNRNPU BACH1	5.84e-04	198	37	3	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIFAP3 TTC3 ATP2B2	5.84e-04	198	37	3	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	SKIL HNRNPU BACH1	5.84e-04	198	37	3	44417089b62056269cac38d3134ff209c05b7007
ToppCell	Caecum-T_cell-Treg\|T_cell / Region, Cell class and subclass	RTKN2 MAP3K1 BACH1	5.84e-04	198	37	3	90a2a75ca078f7088b8739795a9b396113bcbe23
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SKIL HNRNPU BACH1	5.84e-04	198	37	3	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 KIAA0586 SMTN	5.84e-04	198	37	3	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	REV3L KHDRBS1 TTC3	5.93e-04	199	37	3	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	REV3L KHDRBS1 TTC3	5.93e-04	199	37	3	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	ERBB4 TTC3 BACH1	5.93e-04	199	37	3	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	RTKN2 KIAA0586 SMTN	5.93e-04	199	37	3	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	KIFAP3 ERBB4 TTC3	5.93e-04	199	37	3	77b4aa00f14b86ef5db0490be98787e063979541
ToppCell	TCGA-Bile_Duct-Primary_Tumor\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	HNRNPUL1 KHDRBS1 HNRNPU	6.01e-04	200	37	3	0350e5ffd36033099b7e32a1fdd790fff99790dc
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	HNRNPUL1 KHDRBS1 HNRNPU	6.01e-04	200	37	3	ad2a6da0b1ae7a9212a3c91e5eec4baa7481d8dc
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	KIFAP3 HERC1 ATP2B2	6.01e-04	200	37	3	48d801219bc771d6c7e151dc88ca4c179988de85
Computational	Neighborhood of AP3D1	KARS1 HNRNPUL1 KHDRBS1 HNRNPU	1.51e-04	130	23	4	MORF_AP3D1
Computational	Neighborhood of HDAC1	KARS1 HNRNPUL1 KHDRBS1 BAZ2A HNRNPU	1.68e-04	254	23	5	MORF_HDAC1
Computational	Neighborhood of DEK	MSH6 KARS1 HNRNPUL1 KHDRBS1 HNRNPU	2.01e-04	264	23	5	MORF_DEK
Computational	Neighborhood of RPA1	KARS1 KHDRBS1 HNRNPU	2.84e-04	61	23	3	MORF_RPA1
Computational	Neighborhood of MSH2	MSH6 KHDRBS1 HNRNPU	2.84e-04	61	23	3	MORF_MSH2
Computational	Neighborhood of SMC1L1	MSH6 KHDRBS1 HNRNPU	2.98e-04	62	23	3	MORF_SMC1L1
Computational	RNA splicing.	HNRNPUL1 KHDRBS1 HNRNPU	3.43e-04	65	23	3	MODULE_183
Computational	Neighborhood of TERF1	HNRNPUL1 KHDRBS1 HNRNPU	3.75e-04	67	23	3	MORF_TERF1
Computational	Neighborhood of CUL1	KARS1 KHDRBS1 HNRNPU	4.64e-04	72	23	3	MORF_CUL1
Computational	Neighborhood of KPNB1	SUZ12 KHDRBS1 HNRNPU	4.83e-04	73	23	3	GNF2_KPNB1
Computational	Neighborhood of PCNA	MSH6 KARS1 KHDRBS1	7.03e-04	83	23	3	MORF_PCNA
Computational	Neighborhood of CCNI	HNRNPUL1 KHDRBS1 BAZ2A	8.34e-04	88	23	3	MORF_CCNI
Computational	Neighborhood of APEX1	SUZ12 KHDRBS1 HNRNPU	9.49e-04	92	23	3	GNF2_APEX1
Computational	Transcription.	HNRNPUL1 KHDRBS1 HNRNPU	1.07e-03	96	23	3	MODULE_124
Computational	Neighborhood of DAP3	KARS1 KHDRBS1 HNRNPU	1.99e-03	119	23	3	GNF2_DAP3
Computational	Neighborhood of ACTG1	SUZ12 KHDRBS1 HNRNPU	2.24e-03	124	23	3	GCM_ACTG1
Computational	Neighborhood of PPP2CA	KARS1 KHDRBS1 HNRNPU	2.51e-03	129	23	3	MORF_PPP2CA
Computational	Neighborhood of BUB3	KARS1 HNRNPUL1 KHDRBS1 HNRNPU	2.60e-03	277	23	4	MORF_BUB3
Computational	Neighborhood of G22P1	KARS1 KHDRBS1	2.64e-03	36	23	2	GNF2_G22P1
Computational	Neighborhood of MAP2K2	KARS1 HNRNPUL1 KHDRBS1	2.68e-03	132	23	3	MORF_MAP2K2
Computational	Neighborhood of RAD21	KHDRBS1 HNRNPU	2.79e-03	37	23	2	GCM_RAD21
Computational	Neighborhood of ANP32B	SUZ12 HNRNPU	2.79e-03	37	23	2	GNF2_ANP32B
Computational	Neighborhood of FBL	KARS1 HNRNPUL1 KHDRBS1	3.16e-03	140	23	3	MORF_FBL
Computational	Neighborhood of FBL	KARS1 SUZ12 KHDRBS1	3.56e-03	146	23	3	GNF2_FBL
Computational	Neighborhood of MLH1	MSH6 KARS1	3.58e-03	42	23	2	GNF2_MLH1
Computational	Neighborhood of GNB1	HNRNPUL1 KHDRBS1 BAZ2A HNRNPU	3.67e-03	305	23	4	MORF_GNB1
Computational	Neighborhood of RAF1	KHDRBS1 HNRNPU	3.75e-03	43	23	2	GCM_RAF1
Computational	Neighborhood of UBE2I	KARS1 KHDRBS1	3.92e-03	44	23	2	GNF2_UBE2I
Computational	Genes upregulated in subsets of cells of a given type within various tumors	TTC3 HNRNPU	4.85e-03	49	23	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Computational	Genes upregulated in subsets of cells of a given type within various tumors	REV3L MAP3K1	5.04e-03	50	23	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_29_NPC_OPC
Computational	Genes upregulated in subsets of cells of a given type within various tumors	MSH6 SUZ12	5.04e-03	50	23	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Computational	Neighborhood of DENR	KHDRBS1 HNRNPU	5.24e-03	51	23	2	GNF2_DENR
Computational	Neighborhood of CTBP1	KARS1 HNRNPUL1 KHDRBS1	5.28e-03	168	23	3	MORF_CTBP1
Computational	Neighborhood of PPP1CA	KARS1 HNRNPUL1 KHDRBS1	5.28e-03	168	23	3	MORF_PPP1CA
Computational	Neighborhood of G22P1	KARS1 HNRNPUL1 KHDRBS1	5.63e-03	172	23	3	MORF_G22P1
Computational	Neighborhood of RAD23A	KARS1 HNRNPUL1 KHDRBS1 HNRNPU	5.87e-03	348	23	4	MORF_RAD23A
Computational	Neighborhood of HAT1	KARS1 KHDRBS1 HNRNPU	5.91e-03	175	23	3	MORF_HAT1
Computational	Neighborhood of BAG5	KARS1 HNRNPUL1	6.07e-03	55	23	2	MORF_BAG5
Computational	Neighborhood of PPP1CC	KHDRBS1 HNRNPU	6.29e-03	56	23	2	GCM_PPP1CC
Computational	Neighborhood of RAD21	KARS1 KHDRBS1 HNRNPU	6.39e-03	180	23	3	MORF_RAD21
Computational	Neighborhood of DEK	SUZ12 HNRNPU	6.73e-03	58	23	2	GNF2_DEK
Computational	Neighborhood of MCM5	SUZ12 HNRNPU	7.42e-03	61	23	2	GNF2_MCM5
Disease	stomach polyp	ERBB4 TSEN2	5.48e-05	9	37	2	MONDO_0008277
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:0110454 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:0111602 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:3429 (implicated_via_orthology)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:0111269 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:0080719 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:0080326 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH3 MYH13	6.84e-05	10	37	2	DOID:0111596 (implicated_via_orthology)
Disease	cardiomyopathy (implicated_via_orthology)	MYH3 ERBB4 MYH13	9.78e-05	71	37	3	DOID:0050700 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH3 MYH13	1.00e-04	12	37	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH3 MYH13	1.00e-04	12	37	2	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH3 MYH13	1.18e-04	13	37	2	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH3 MYH13	1.59e-04	15	37	2	DOID:0050646 (implicated_via_orthology)
Disease	Intellectual Disability	ZBTB40 KARS1 SUZ12 TSEN2 HNRNPU	2.28e-04	447	37	5	C3714756
Disease	Adenocarcinoma of large intestine	MSH6 ERBB4 DLC1	2.39e-04	96	37	3	C1319315
Disease	platelet component distribution width	DLC1 HERC1 MYH13 BAZ2A NUP35 EIF2B3	3.25e-04	755	37	6	EFO_0007984
Disease	apolipoprotein L1 measurement	DLC1 CYP11B1	4.51e-04	25	37	2	EFO_0021854
Disease	colorectal cancer (is_implicated_in)	ERBB4 AMER1 DLC1	4.72e-04	121	37	3	DOID:9256 (is_implicated_in)
Disease	FEV/FEC ratio	SUZ12 DLC1 HERC1 TSEN2 MAP3K1 KIAA0586 SMTN	7.31e-04	1228	37	7	EFO_0004713
Disease	brain infarction (biomarker_via_orthology)	ATP2B2 CYP11B1	7.88e-04	33	37	2	DOID:3454 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKMEVEENGIKMCKP	ERBB4	311	Q15303
MLKCDESKLAMEPEE	BACH1	276	O14867
ILEEMKKPTEDMCLT	BAZ2A	816	Q9UIF9
EKMACKDPEKPMEAC	AMER1	251	Q5JTC6
MVKKVIEPMACDGLR	ATP2B2	656	Q01814
MPVILKEQCMTEGKR	CCNB3	381	Q8WWL7
FKVGMKLEAVDLMEP	L3MBTL2	536	Q969R5
MVCGMPEISVEVLKK	HERC1	4726	Q15751
ETKCMIKMKLDVPEQ	DNAH8	611	Q96JB1
PEEKKDCEVVMMIGL	HNRNPU	491	Q00839
KVMCKIIGIMEEVAD	MSH6	866	P52701
EFKMKMKPDIVCIPD	EIF2B3	66	Q9NR50
AGMVCVMLPEDVEKL	CYP11B1	86	P15538
VKKFLVPDMMDDICQ	KHDRBS1	251	Q07666
VEMDIVEKLVKMIPC	KIFAP3	341	Q92845
KSKAECEILMMVGLP	HNRNPUL1	416	Q9BUJ2
IMIGVKPCIDKSVME	NUP35	236	Q8NFH5
KDEEEQMCPICLLGM	MAP3K1	436	Q13233
CCEELMKIEIMSPRK	RTKN2	401	Q8IZC4
DKEMESPECMKRIKV	TSEN2	431	Q8NCE0
ESLKDMMDPVAVCKK	PSAPL1	451	Q6NUJ1
VICEDDKGKIMEEVM	SKIL	521	P12757
MVEELEKALGMKLPE	KARS1	396	Q15046
LIMKGTEMCPKSEDV	PRPF6	331	O94906
MDLAACIELIEKPMG	MYH3	516	P11055
MIAECKKLFQVPEEM	DLC1	1276	Q96QB1
EIGKECEMLSKMVME	CCDC110	696	Q8TBZ0
TMQKPDKVEDGLEMC	ZNF804B	1121	A4D1E1
EGMLRPQVKEEIICM	TRPM6	336	Q9BX84
MVEDKKIVIMPCKCA	REV3L	1986	O60673
EVAMQEMEECPISKK	SUZ12	316	Q15022
DCIEEGELMKMKGNE	TTC3	226	P53804
GMDLAACIELIEKPM	MYH13	516	Q9UKX3
VEPEEMLDVKMEDIK	TMED1	141	Q13445
LVEVDDMMIMGKKPD	SMTN	876	P53814
EICAEKGDDMPAIML	KIAA0586	1081	Q9BVV6
EMCSEIKGPQKEMIV	ZBTB40	266	Q9NUA8