Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1A CACNA1E TRPM4 PIEZO2 ABCC9 HTR3C TRPM1	4.15e-05	343	55	7	GO:0005261
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1A SLC43A2 CACNA1E TRPM4 TMEM144 ABCA3 PIEZO2 ATP13A1 ABCC9 HTR3C TRPM1 SLC44A4	7.05e-05	1180	55	12	GO:0022857
GeneOntologyMolecularFunction	transporter activity	CACNA1A SLC43A2 CACNA1E TRPM4 TMEM144 ABCA3 PIEZO2 ATP13A1 ABCC9 HTR3C TRPM1 SLC44A4	1.63e-04	1289	55	12	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1A CACNA1E TRPM4 PIEZO2 ABCC9 HTR3C TRPM1	2.53e-04	459	55	7	GO:0005216
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1A CACNA1E	2.65e-04	9	55	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1A CACNA1E	2.65e-04	9	55	2	GO:0099626
GeneOntologyMolecularFunction	gated channel activity	CACNA1A CACNA1E TRPM4 PIEZO2 ABCC9 HTR3C	3.04e-04	334	55	6	GO:0022836
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA3 ATP13A1 ABCC9	3.33e-04	49	55	3	GO:0140359
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1A CACNA1E TRPM4 PIEZO2 ATP13A1 ABCC9 HTR3C TRPM1	4.39e-04	664	55	8	GO:0008324
GeneOntologyMolecularFunction	calcium channel activity	CACNA1A CACNA1E TRPM4 TRPM1	4.39e-04	129	55	4	GO:0005262
GeneOntologyMolecularFunction	channel activity	CACNA1A CACNA1E TRPM4 PIEZO2 ABCC9 HTR3C TRPM1	5.68e-04	525	55	7	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1A CACNA1E TRPM4 PIEZO2 ABCC9 HTR3C TRPM1	5.74e-04	526	55	7	GO:0022803
GeneOntologyMolecularFunction	E-box binding	BHLHE23 BHLHE22 TAL1	6.36e-04	61	55	3	GO:0070888
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNA1E	6.64e-04	14	55	2	GO:0008331
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1A CACNA1E TRPM4 TRPM1	7.94e-04	151	55	4	GO:0015085
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1A CACNA1E TRPM4 PIEZO2 ATP13A1 ABCC9 HTR3C TRPM1	1.39e-03	793	55	8	GO:0015075
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1A CACNA1E TRPM4 ABCC9	1.58e-03	182	55	4	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1A CACNA1E TRPM4 ABCC9	1.65e-03	184	55	4	GO:0022832
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1A CACNA1E TRPM4 ATP13A1 ABCC9 TRPM1	1.71e-03	465	55	6	GO:0046873
GeneOntologyMolecularFunction	syntaxin binding	CACNA1A ABCC9 VPS54	1.78e-03	87	55	3	GO:0019905
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA3 ATP13A1 ABCC9	3.38e-03	109	55	3	GO:0042626
GeneOntologyMolecularFunction	calmodulin binding	CACNA1A TRPM4 ACE IQGAP3	3.69e-03	230	55	4	GO:0005516
GeneOntologyMolecularFunction	mitogen-activated protein kinase binding	TAB1 ACE	4.18e-03	35	55	2	GO:0051019
GeneOntologyMolecularFunction	SNARE binding	CACNA1A ABCC9 VPS54	6.26e-03	136	55	3	GO:0000149
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TRPM4 ABCC9 HTR3C	6.78e-03	140	55	3	GO:0099094
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1A CACNA1E	7.13e-03	46	55	2	GO:0005245
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA3 ATP13A1 NAV1 ABCC9 DNAH9	7.22e-03	441	55	5	GO:0016887
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1A CACNA1E TRPM4 ATP13A1 ABCC9 TRPM1	7.36e-03	627	55	6	GO:0022890
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1A CACNA1E ABCC9	8.50e-03	152	55	3	GO:0022843
GeneOntologyBiologicalProcess	import across plasma membrane	CACNA1A SLC43A2 CACNA1E TRPM4 ABCC9 TRPM1	3.31e-05	230	55	6	GO:0098739
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	CACNA1A CACNA1E TRPM4 ABCC9 TRPM1	3.80e-05	142	55	5	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	CACNA1A CACNA1E TRPM4 ABCC9 TRPM1	3.80e-05	142	55	5	GO:0098659
GeneOntologyBiologicalProcess	coronary vasculature development	ABCC9 TAB1 CPLANE1 ACE	7.11e-05	83	55	4	GO:0060976
GeneOntologyBiologicalProcess	retina morphogenesis in camera-type eye	BHLHE23 BHLHE22 TRPM1 CRB1	9.75e-05	90	55	4	GO:0060042
GeneOntologyBiologicalProcess	calcium ion import	CACNA1A CACNA1E TRPM1 ACE	1.36e-04	98	55	4	GO:0070509
GeneOntologyBiologicalProcess	neural retina development	BHLHE23 BHLHE22 TRPM1 CRB1	1.58e-04	102	55	4	GO:0003407
GeneOntologyBiologicalProcess	acetylcholine secretion	CACNA1A SLC44A4	1.93e-04	8	55	2	GO:0061526
GeneOntologyBiologicalProcess	anterior commissure morphogenesis	BHLHE22 WDR47	1.93e-04	8	55	2	GO:0021960
GeneOntologyBiologicalProcess	protein localization to ciliary transition zone	CC2D2A CPLANE1	2.48e-04	9	55	2	GO:1904491
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1A CACNA1E TRPM1	2.85e-04	48	55	3	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1A CACNA1E TRPM1	2.85e-04	48	55	3	GO:1902656
GeneOntologyBiologicalProcess	protein targeting to vacuole	PIK3C3 VPS13C VPS54	3.03e-04	49	55	3	GO:0006623
GeneOntologyBiologicalProcess	post-embryonic animal morphogenesis	VPS54 CRB1	3.10e-04	10	55	2	GO:0009886
GeneOntologyBiologicalProcess	eye photoreceptor cell development	BHLHE23 TRPM1 CRB1	3.61e-04	52	55	3	GO:0042462
GeneOntologyBiologicalProcess	acetylcholine transport	CACNA1A SLC44A4	4.53e-04	12	55	2	GO:0015870
GeneOntologyBiologicalProcess	acetate ester transport	CACNA1A SLC44A4	5.34e-04	13	55	2	GO:1901374
MousePheno	abnormal channel response	CACNA1A CACNA1E ABCC9 TRPM1	4.27e-06	33	47	4	MP:0003484
Domain	GPHH_dom	CACNA1A CACNA1E	1.77e-04	7	55	2	IPR031649
Domain	VDCC_a1su_IQ	CACNA1A CACNA1E	1.77e-04	7	55	2	IPR014873
Domain	Ca_chan_IQ	CACNA1A CACNA1E	1.77e-04	7	55	2	SM01062
Domain	Ca_chan_IQ	CACNA1A CACNA1E	1.77e-04	7	55	2	PF08763
Domain	GPHH	CACNA1A CACNA1E	1.77e-04	7	55	2	PF16905
Domain	Ion_trans_dom	CACNA1A CACNA1E TRPM4 TRPM1	3.53e-04	114	55	4	IPR005821
Domain	Ion_trans	CACNA1A CACNA1E TRPM4 TRPM1	3.53e-04	114	55	4	PF00520
Domain	VDCCAlpha1	CACNA1A CACNA1E	3.77e-04	10	55	2	IPR002077
Domain	AAA+_ATPase	ABCA3 NAV1 ABCC9 DNAH9	8.52e-04	144	55	4	IPR003593
Domain	AAA	ABCA3 NAV1 ABCC9 DNAH9	8.52e-04	144	55	4	SM00382
Domain	-	BHLHE23 BHLHE22 TAL1	4.07e-03	109	55	3	4.10.280.10
Domain	HLH	BHLHE23 BHLHE22 TAL1	4.28e-03	111	55	3	PF00010
Domain	HLH	BHLHE23 BHLHE22 TAL1	4.84e-03	116	55	3	SM00353
Domain	BHLH	BHLHE23 BHLHE22 TAL1	4.96e-03	117	55	3	PS50888
Domain	bHLH_dom	BHLHE23 BHLHE22 TAL1	5.08e-03	118	55	3	IPR011598
Domain	ABC_transporter_CS	ABCA3 ABCC9	6.80e-03	42	55	2	IPR017871
Domain	ABC_TRANSPORTER_2	ABCA3 ABCC9	8.81e-03	48	55	2	PS50893
Domain	ABC_tran	ABCA3 ABCC9	8.81e-03	48	55	2	PF00005
Domain	ABC_TRANSPORTER_1	ABCA3 ABCC9	9.16e-03	49	55	2	PS00211
Domain	ABC_transporter-like	ABCA3 ABCC9	9.53e-03	50	55	2	IPR003439
Domain	TPR_8	SGTA FKBP5	1.07e-02	53	55	2	PF13181
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	CACNA1E CDK18 VPS13C TAB1 RALGAPA2 PTGFR	7.47e-07	199	55	6	23382691
Pubmed	Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.	CACNA1A CACNA1E	2.46e-06	2	55	2	16381801
Pubmed	Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform.	TRPM4 TRPM1	2.46e-06	2	55	2	11535825
Pubmed	The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.	CACNA1A CACNA1E	7.36e-06	3	55	2	38996073
Pubmed	Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.	CACNA1A CACNA1E	7.36e-06	3	55	2	24523520
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	SLC43A2 TRPM4 PLLP TMEM144 ABCA3 RPN2 ATP13A1 TSPAN4	1.33e-05	697	55	8	28298427
Pubmed	Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.	CACNA1A CACNA1E	1.47e-05	4	55	2	32616470
Pubmed	Cerebellar granule cell signaling is indispensable for normal motor performance.	CACNA1A CACNA1E	1.47e-05	4	55	2	37141091
Pubmed	Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility.	RPN2 SGTA PSMD8	1.97e-05	33	55	3	17558393
Pubmed	Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.	CACNA1A CACNA1E	2.45e-05	5	55	2	8825650
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1A CACNA1E	2.45e-05	5	55	2	15451373
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1A CACNA1E	2.45e-05	5	55	2	11296258
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	TRPM4 PLLP PIEZO2 NAV1 SMPD4 RALGAPA2 ARAP2	3.11e-05	569	55	7	30639242
Pubmed	An action potential initiation mechanism in distal axons for the control of dopamine release.	CACNA1A CACNA1E	3.67e-05	6	55	2	35324301
Pubmed	Mechanoreceptor synapses in the brainstem shape the central representation of touch.	PIEZO2 PTGFR	3.67e-05	6	55	2	34637701
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	CACNA1A CACNA1E	3.67e-05	6	55	2	12827191
Pubmed	Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.	CACNA1A CACNA1E	3.67e-05	6	55	2	9238069
Pubmed	Rebuilding essential active zone functions within a synapse.	CACNA1A CACNA1E	5.13e-05	7	55	2	35176221
Pubmed	Classification and evolutionary analysis of the basic helix-loop-helix gene family in the green anole lizard, Anolis carolinensis.	BHLHE23 BHLHE22	5.13e-05	7	55	2	23756994
Pubmed	Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.	PIK3C3 SGTA VPS54	5.78e-05	47	55	3	26687681
Pubmed	LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage.	ACE TAL1	6.83e-05	8	55	2	27880904
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1A CACNA1E	8.78e-05	9	55	2	16382099
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SCFD2 CDK18 URB1 RPN2 ATP13A1 SGTA SMPD4 PSMD8 CLUH FKBP5	9.99e-05	1487	55	10	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRPM4 TMEM144 PIK3C3 VPS13C SGTA TSPAN4 NAV1 VPS54 ARMC2 FKBP5	1.01e-04	1489	55	10	28611215
Pubmed	Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity.	RPN2 PSMD8	1.10e-04	10	55	2	29290612
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	CACNA1A ZMYND8 DNAH9	1.32e-04	62	55	3	16147992
Pubmed	Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening.	BHLHE23 BHLHE22	1.60e-04	12	55	2	14516699
Pubmed	Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.	TRPM4 TRPM1	1.60e-04	12	55	2	19850157
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1A CACNA1E	2.54e-04	15	55	2	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1A CACNA1E	2.54e-04	15	55	2	24453333
Pubmed	Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar cells in retina.	BHLHE22 TRPM1	2.90e-04	16	55	2	29559301
Pubmed	Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.	VPS13C ZMYND8	3.70e-04	18	55	2	27984743
Pubmed	Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.	RPN2 PSMD8 TAB1	4.82e-04	96	55	3	34599178
Pubmed	Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.	BHLHE23 BHLHE22 TAL1	5.12e-04	98	55	3	18557763
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	CC2D2A TAB1 CPLANE1	5.43e-04	100	55	3	25807483
Pubmed	Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.	ABCA3 ABCC9	6.08e-04	23	55	2	10708515
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPM4 TRPM1	6.63e-04	24	55	2	33884443
Pubmed	Brugada Syndrome	TRPM4 ABCC9	6.63e-04	24	55	2	20301690
Pubmed	Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex.	VPS13C SGTA	6.63e-04	24	55	2	35543156
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	URB1 FOXRED2 RPN2 ATP13A1 SGTA PSMD8 IQGAP3	6.84e-04	942	55	7	31073040
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPM4 TRPM1	7.20e-04	25	55	2	16382100
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	URB1 FOXRED2 RPN2 SGTA SMPD4 PSMD8 IQGAP3 FKBP5	7.66e-04	1257	55	8	37317656
Pubmed	An introduction to TRP channels.	TRPM4 TRPM1	8.40e-04	27	55	2	16460286
Pubmed	A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes.	RPN2 PSMD8	8.40e-04	27	55	2	16990800
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	SCFD2 TRPM4 OTULIN ATP13A1 SMPD4	8.64e-04	468	55	5	31056421
Pubmed	Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation.	BHLHE23 BHLHE22	9.70e-04	29	55	2	25556712
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ATP13A1 VPS13C NAV1 SMPD4 CLUH FKBP5	1.04e-03	733	55	6	34672954
Pubmed	Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.	VPS13C ZMYND8	1.11e-03	31	55	2	25838543
Pubmed	STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1.	TAB1 FKBP5	1.11e-03	31	55	2	28089446
Pubmed	SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.	OTULIN TAB1	1.11e-03	31	55	2	27307491
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	CDK18 LAMTOR2 TAF1A OR13G1 TAL1 PTGFR CRB1	1.16e-03	1031	55	7	16710414
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPM4 TRPM1	1.26e-03	33	55	2	19834762
Pubmed	Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development.	BHLHE23 BHLHE22	1.26e-03	33	55	2	20463215
Pubmed	Joubert Syndrome	CC2D2A CPLANE1	1.33e-03	34	55	2	20301500
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1A CACNA1E ABCC9	1.41e-03	139	55	3	16985003
Cytoband	4q32.1	TMEM144 GASK1B	4.50e-04	26	55	2	4q32.1
Cytoband	19p13	CACNA1A SGTA	4.85e-04	27	55	2	19p13
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA1E	1.28e-03	26	37	2	253
GeneFamily	Basic helix-loop-helix proteins	BHLHE23 BHLHE22 TAL1	1.46e-03	110	37	3	420
GeneFamily	Transient receptor potential cation channels	TRPM4 TRPM1	1.49e-03	28	37	2	249
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2 TRPM1	3.03e-06	182	55	5	d524ad5cf00f05ee27c9db2ffa2d4e30a1e2e21a
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PIEZO2 ACE TAL1 GASK1B ARAP2	3.83e-06	191	55	5	44c596984c6196f6014e0e405dbe5560841e54ff
ToppCell	E16.5-samps-Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PIEZO2 ACE TAL1 GASK1B ARAP2	3.83e-06	191	55	5	e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 NAV1 ACE ARAP2	4.13e-06	194	55	5	fc40ab57be3a15c043e3414c2c678c1dc52207c8
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 NAV1 ACE ARAP2	4.13e-06	194	55	5	8deeb3e00237e3d9ad5a1457cd0061576421b9e9
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 NAV1 ACE ARAP2	4.13e-06	194	55	5	b81801fb16e8bd0d6083fe32866051d3c60f3dc7
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 NAV1 ACE ARAP2	4.13e-06	194	55	5	c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|356C / Donor, Lineage, Cell class and subclass (all cells)	CACNA1A TAL1 IQGAP3 CRB1	3.55e-05	150	55	4	6bdf9df586f348641a25a445e83a41e47e7f347e
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCFD2 CACNA1E GPR150 WDR47	4.24e-05	157	55	4	fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCFD2 CACNA1E GPR150 WDR47	4.24e-05	157	55	4	66a191cef4aa00811bb04462310d012610006f85
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXRED2 NAV1 TAL1 GASK1B	4.56e-05	160	55	4	ca212634cf1875238071d1800ecdf34979a553fb
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXRED2 NAV1 TAL1 GASK1B	4.56e-05	160	55	4	5d22c86deead516444349d495998e04586be4396
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRID2IP SLC44A4 ARMC2 DNAH9	5.02e-05	164	55	4	9e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A CACNA1E TRPM1 DNAH9	5.39e-05	167	55	4	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIEZO2 ACE TAL1 ARAP2	5.64e-05	169	55	4	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIEZO2 ACE TAL1 ARAP2	5.64e-05	169	55	4	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PLLP PIEZO2 NAV1 ACE	6.32e-05	174	55	4	cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PLLP ACE TAL1 GASK1B	6.90e-05	178	55	4	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 TRPM4 GASK1B ARAP2	7.05e-05	179	55	4	820289f14ecf165758529c236bb220bb1a744f02
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 TRPM4 GASK1B ARAP2	7.05e-05	179	55	4	e5f781d35449628a7f356d71e26231dd63482eec
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PLLP PIEZO2 ACE ARAP2	7.36e-05	181	55	4	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 TMEM144 PIEZO2 TRPM1	7.36e-05	181	55	4	a8e9ea73c24109a5d4d28bc0577cc869ad932a4d
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	IQGAP3 GASK1B ARAP2 CRB1	7.52e-05	182	55	4	f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ACE TAL1 GASK1B ARAP2	7.52e-05	182	55	4	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	7.68e-05	183	55	4	5472cdce6d99314d229418412acf1fff6340db7d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	7.68e-05	183	55	4	93213124e55d1b673dd345188caf8b5bd31d99fe
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	BTBD16 ABCA3 ABCC9 PTGFR	7.68e-05	183	55	4	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	7.85e-05	184	55	4	f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	7.85e-05	184	55	4	5939527d24d299e562e707469c9123890edd76be
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.01e-05	185	55	4	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN4 ABCC9 ACE PTGFR	8.01e-05	185	55	4	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.01e-05	185	55	4	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN4 ABCC9 ACE PTGFR	8.01e-05	185	55	4	049d793d043d5d434f143025de49dd210d18756c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.01e-05	185	55	4	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	facs-Skin-nan-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN4 ABCC9 ACE PTGFR	8.01e-05	185	55	4	63200c42565eea596f9b00728e70e544b8d50a7f
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1E TSPAN4 NAV1 TAL1	8.18e-05	186	55	4	9579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.18e-05	186	55	4	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLLP PIEZO2 SLC44A4 DNAH9	8.18e-05	186	55	4	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HTR3C RALGAPA2 ACE TAL1	8.18e-05	186	55	4	f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.18e-05	186	55	4	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|356C / Donor, Lineage, Cell class and subclass (all cells)	HTR3C RALGAPA2 ACE TAL1	8.18e-05	186	55	4	2b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.35e-05	187	55	4	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.35e-05	187	55	4	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	E17.5-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.35e-05	187	55	4	1f358d02ec69d44dea2e2831af9473ed05dcf8cc
ToppCell	E17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PIEZO2 ACE GASK1B ARAP2	8.35e-05	187	55	4	e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCell	P15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.35e-05	187	55	4	60f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCell	P15-Endothelial-unknown_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.35e-05	187	55	4	d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCell	E17.5-Endothelial-unknown_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.35e-05	187	55	4	da885c26ccc5189b1ff1f607552e00a5c0e49e7e
ToppCell	E17.5-Endothelial-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PIEZO2 ACE GASK1B ARAP2	8.35e-05	187	55	4	61b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.52e-05	188	55	4	b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.52e-05	188	55	4	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.52e-05	188	55	4	60242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	BTBD16 ABCA3 ABCC9 PTGFR	8.52e-05	188	55	4	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.70e-05	189	55	4	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	P07-Endothelial-unknown_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.70e-05	189	55	4	f515a04ae1746257d4568cea13a3dd75b4b05275
ToppCell	P07-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.70e-05	189	55	4	fcfb28bd96471affc13e55aa7228f594aaa967cd
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.70e-05	189	55	4	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PIEZO2 NAV1 ACE ARAP2	8.88e-05	190	55	4	5130fb325f80f591b9b36beacb8072c4472304f2
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.88e-05	190	55	4	6b101359f397020a21e2bfd15851cb48e71f4502
ToppCell	P03-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.88e-05	190	55	4	347c7bf67ade235a4e2320db6a75ce0dab8744f9
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PLLP ACE TAL1 GASK1B	8.88e-05	190	55	4	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PIEZO2 NAV1 ACE ARAP2	8.88e-05	190	55	4	1357bd4527399d7013ee33272bda7453f472999a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.88e-05	190	55	4	396b7225c2430db3dc55a3d0db70239b71987229
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	8.88e-05	190	55	4	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	P03-Endothelial-unknown_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLLP PIEZO2 ACE ARAP2	8.88e-05	190	55	4	0c7da05fbd3f095dde7550585209c056f0b76990
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	9.06e-05	191	55	4	2110a1dd10730ad7ee7a265fb1716ab3ddafcf4a
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 NAV1 ARAP2	9.06e-05	191	55	4	718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 NAV1 ARAP2	9.06e-05	191	55	4	454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 PLLP TMEM144 PIEZO2	9.06e-05	191	55	4	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	Endothelial-B\|World / shred on cell class and cell subclass (v4)	PLLP PIEZO2 ACE ARAP2	9.06e-05	191	55	4	8b7857dee69d0ba3e59e230c9fd372e14695299e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	BTBD16 ABCA3 ABCC9 PTGFR	9.25e-05	192	55	4	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN4 ABCC9 TAL1 GASK1B	9.25e-05	192	55	4	a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 ACE ARAP2	9.25e-05	192	55	4	2360824910cd471c8286ca369ba144d90d984602
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLLP PIEZO2 ACE GASK1B	9.25e-05	192	55	4	4fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLLP PIEZO2 ACE GASK1B	9.25e-05	192	55	4	be75783d9578974b662e1cb13bd3442a921fd50a
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDK18 PLLP TMEM144 PIEZO2	9.25e-05	192	55	4	8dc3016601148243196e925641c9507e9d58c9e0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 NAV1 TAL1 GASK1B	9.25e-05	192	55	4	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	367C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLLP NAV1 HTR3C ACE	9.43e-05	193	55	4	5c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 ACE ARAP2	9.43e-05	193	55	4	b6b065b0c2ad31d1488dfa970450b29a8ac1f3aa
ToppCell	367C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLLP NAV1 HTR3C ACE	9.43e-05	193	55	4	d4b58eee97043b4337ec36c40f9af6499d864df9
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO2 TSPAN4 ABCC9 GASK1B	9.43e-05	193	55	4	96c85b250d04b5f400512097d925061c6dc2906b
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIEZO2 NAV1 ACE ARAP2	9.43e-05	193	55	4	097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIEZO2 NAV1 RALGAPA2 ACE	9.43e-05	193	55	4	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 ACE ARAP2	9.43e-05	193	55	4	4513e6cb3f86d9cc56e7892fbe11a861335bd179
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 ACE ARAP2	9.43e-05	193	55	4	ac1073bf4d3868841226b850b058f1e27326a14e
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 NAV1 ARAP2	9.62e-05	194	55	4	50fa7c7940b113427c87fbdb9057fef8e1ce52c5
ToppCell	droplet-Lung-LUNG-1m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLLP PIEZO2 TSPAN4 ACE	9.62e-05	194	55	4	68efc6df31479839a3bd5fe9fbc98ddceecc3b10
ToppCell	15-Airway-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	PLLP ACE TAL1 GASK1B	9.62e-05	194	55	4	ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 PLLP PIEZO2 SLC44A4	9.62e-05	194	55	4	715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCell	15-Airway-Endothelial-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	PLLP ACE TAL1 GASK1B	9.62e-05	194	55	4	f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLLP PIEZO2 TSPAN4 ACE	9.62e-05	194	55	4	03985e4ab10f140f758e70dc7bfaa059b4e3bb18
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLLP PIEZO2 ACE ARAP2	9.62e-05	194	55	4	46e36817fd1ed27af8013375214c38c9a9271640
ToppCell	PND03-Endothelial-Endothelial_blood-vessel\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIEZO2 NAV1 ACE ARAP2	9.62e-05	194	55	4	f93f5148b136819d87faef89707dbaba07d6c2b5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIEZO2 NAV1 ACE ARAP2	9.82e-05	195	55	4	d700e959e060932e3854a9cf294799465efbe18b
ToppCell	PND03-Endothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIEZO2 NAV1 ACE ARAP2	1.00e-04	196	55	4	a529681d822a95dd1980b7b1c71dc61aaf0baecd
ToppCell	IPF-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	PLLP NAV1 ACE FKBP5	1.00e-04	196	55	4	8f0f72ead06abe02b575e443552eacc2151077ef
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO2 TSPAN4 RALGAPA2 TAL1	1.02e-04	197	55	4	407231542fa1ffd540dcb61435c0575e71f59725
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-D_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	PLLP ABCA3 TSPAN4 PSMD8	1.04e-04	198	55	4	963b7ff8c5322d9290bbaf42137bb8fdd0672db9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDK18 PLLP TMEM144 PIEZO2	1.06e-04	199	55	4	214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDK18 PLLP TMEM144 PIEZO2	1.08e-04	200	55	4	acdef0b9096c774040948fc75621ff2b08ea2ee8
Disease	familial hemiplegic migraine 1 (implicated_via_orthology)	CACNA1A CACNA1E	9.49e-06	3	53	2	DOID:0111181 (implicated_via_orthology)
Disease	migraine (implicated_via_orthology)	CACNA1A CACNA1E	1.89e-05	4	53	2	DOID:6364 (implicated_via_orthology)
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A CACNA1E	6.61e-05	7	53	2	DOID:0050951 (implicated_via_orthology)
Disease	cerebellar ataxia (implicated_via_orthology)	CACNA1A VPS13C	8.80e-05	8	53	2	DOID:0050753 (implicated_via_orthology)
Disease	serum IgG glycosylation measurement	CACNA1E CDK18 VPS13C TAB1 RALGAPA2 PTGFR	3.41e-04	523	53	6	EFO_0005193
Disease	parahippocampal gyrus volume measurement	ZMYND8 PTGFR	4.75e-04	18	53	2	EFO_0010318
Disease	sensorineural hearing loss (implicated_via_orthology)	SLC44A4 DNAH9	5.31e-04	19	53	2	DOID:10003 (implicated_via_orthology)
Disease	Disorder of eye	CC2D2A TRPM1 CPLANE1 CRB1	5.76e-04	212	53	4	C0015397
Disease	Familial aplasia of the vermis	CC2D2A CPLANE1	5.89e-04	20	53	2	cv:C0431399
Disease	Brugada Syndrome (disorder)	TRPM4 ABCC9	8.52e-04	24	53	2	C1142166
Disease	depressive symptom measurement	CACNA1A CACNA1E ZMYND8 VPS54 CRB1	9.95e-04	426	53	5	EFO_0007006
Disease	Depressive Symptoms	ABCC9 ACE	1.00e-03	26	53	2	C0086132
Disease	Ciliopathies	CC2D2A CPLANE1 CRB1	1.03e-03	110	53	3	C4277690
Disease	chronic obstructive pulmonary disease	ABCA3 NAV1 CC2D2A VPS54 ARMC2 ARAP2	1.42e-03	688	53	6	EFO_0000341
Disease	FEV/FEC ratio	SCFD2 BTBD16 ABCA3 VPS13C NAV1 ARMC2 TAL1 ARAP2	1.47e-03	1228	53	8	EFO_0004713

Protein segments in the cluster

Peptide	Gene	Start	Entry
LMLVNLKVNLLLVDY	ABHD13	136	Q7L211
NSLKNVFNILIVYML	CACNA1A	1371	O00555
LKNVFNILIVYKLFM	CACNA1E	1286	Q15878
INYLLKMALEKIAFL	ACE	451	P12821
TMLLWVFLQLNYKIQ	BTBD16	276	Q32M84
NVKIFMFQLLRGLAY	CDK18	241	Q07002
LLLAKNYILMQAQAL	BHLHE22	286	Q8NFJ8
IATLLLAKNYILMQA	BHLHE23	141	Q8NDY6
QMFKILALNALILAY	ATP13A1	986	Q9HD20
YIAELLLKLLVSNNM	ARMC2	676	Q8NEN0
MAVLRQLALLLWKNY	ABCA3	1	Q99758
LLGYNVFLLMMNDLL	HTR3C	286	Q8WXA8
INLRGALLAMIYNKI	ABCC9	381	O60706
IKDFLMSINLEQYLL	ARAP2	11	Q8WZ64
IVLFNLYLFQLHMKL	PLLP	81	Q9Y342
LLAAFLNLAMCYLKL	FKBP5	316	Q13451
FLGNMLIIIAKIYNN	OR13G1	36	Q8NGZ3
LAYNLLKRNLFAEIM	nan	316	A8MVJ9
LRLIFYMGAMNNILK	SLC43A2	336	Q8N370
ILSNSLAIAILMKAY	PTGFR	41	P43088
LYQMFGVLADVILLK	FOXRED2	446	Q8IWF2
FLQILLKYMVIQAAS	RALGAPA2	211	Q2PPJ7
LLQLQYEGVAVMKLF	IQGAP3	1596	Q86VI3
NLLMYTKLFVGFLNR	SMPD4	476	Q9NXE4
AVKFLMLNRAIELYN	OTULIN	231	Q96BN8
KMALFDFLLQIYNRL	GASK1B	366	Q6UWH4
LAKILEFVLAMGNYL	GRID2IP	1016	A4D2P6
MLFAFIYLALQKRQI	CASD1	611	Q96PB1
NRFLIAKQYFLLADM	CC2D2A	981	Q9P2K1
LLKMVADNLNGVYIL	CPLANE1	691	Q9H799
FGMLKAKAQALVQYL	LAMTOR2	101	Q9Y2Q5
FIKFLNRNAYIMIAI	SLC44A4	551	Q53GD3
KLTYLAQLTFQILLM	DNAH9	3751	Q9NYC9
MALKNINYLLIFYLS	CRB1	1	P82279
IEQLSYLLKFAIQKM	ZMYND8	151	Q9ULU4
QKPLFAIFLIMYLLA	OR1L6	61	Q8NGR2
LMAMLLKLQEAANYI	NAV1	1846	Q8NEY1
MDNKKRLAYAIIQFL	SGTA	1	O43765
AMAVVAVLLNNKLYV	TAB1	166	Q15750
NEILRLAMKYINFLA	TAL1	226	P17542
LAMKYINFLAKLLND	TAL1	231	P17542
MNYLKISLQHALYLL	TAF1A	131	Q15573
KMDFLLVQLALADLY	GPR150	81	Q8NGU9
DLLMYLLQLVQALKY	PIK3C3	391	Q8NEB9
LMSYIQLFKNNLKAL	SCFD2	386	Q8WU76
MQQVLLAAKQVLLYL	URB1	921	O60287
RYLLFMKLAALQLMQ	CLUH	616	O75153
NNRLFQLVMKGLLYE	WDR47	191	O94967
QLNMFQTLKYLAILG	RPN2	596	P04844
EIKGLQNYLLMILAF	TMEM144	316	Q7Z5S9
YLRNNLLMLAILAFE	PIEZO2	1056	Q9H5I5
VYLHKFLMSLLNFLN	VPS13C	1191	Q709C8
MACYLLVANILLVNL	TRPM1	1056	Q7Z4N2
LQAVKYLMFAFNLLF	TSPAN4	6	O14817
AYMHQLLGLNLLFLL	PSMD8	186	P48556
ANILLVNLLIAMFSY	TRPM4	1031	Q8TD43
QMLFLRINASYKLHL	VPS54	911	Q9P1Q0