Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP NCOA6 EP300

6.75e-0721173GO:0042975
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

6.82e-072172GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

6.82e-072172GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

2.05e-063172GO:0043993
GeneOntologyMolecularFunctiontranscription coactivator activity

ARID1A CREBBP NCOA6 TSC22D1 EP300

4.15e-06303175GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

ARID1A MED15 CREBBP NCOA6 TSC22D1 EP300

4.60e-06562176GO:0003712
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

ARID1A CREBBP GTF2A1 NCOA6 EP300

1.95e-05417175GO:0061629
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

7.12e-0515172GO:0010484
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

ARID1A CREBBP GTF2A1 NCOA6 EP300

9.56e-05582175GO:0140297
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NCOA6 EP300

1.28e-0420172GO:0035259
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor binding

CREBBP GTF2A1

2.36e-0427172GO:0001091
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

ARID1A MED15 CREBBP NCOA6 TSC22D1 EP300

2.70e-041160176GO:0030674
GeneOntologyMolecularFunctionmRNA 3'-UTR AU-rich region binding

TIA1 KHSRP

2.73e-0429172GO:0035925
GeneOntologyMolecularFunctiontranscription factor binding

ARID1A CREBBP GTF2A1 NCOA6 EP300

3.19e-04753175GO:0008134
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300

4.46e-0437172GO:0043425
GeneOntologyMolecularFunctionnuclear receptor binding

ARID1A NCOA6 EP300

4.99e-04187173GO:0016922
GeneOntologyMolecularFunctionmolecular adaptor activity

ARID1A MED15 CREBBP NCOA6 TSC22D1 EP300

6.26e-041356176GO:0060090
GeneOntologyMolecularFunctionhistone acetyltransferase activity

CREBBP EP300

8.49e-0451172GO:0004402
GeneOntologyMolecularFunctiontranscription coactivator binding

CREBBP EP300

9.51e-0454172GO:0001223
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

CREBBP EP300

9.87e-0455172GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

CREBBP EP300

1.17e-0360172GO:0034212
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

CREBBP GTF2A1

1.33e-0364172GO:0140296
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

CREBBP GTF2A1

1.42e-0366172GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

CREBBP GTF2A1

1.42e-0366172GO:0001098
GeneOntologyMolecularFunctionp53 binding

CREBBP EP300

1.92e-0377172GO:0002039
GeneOntologyMolecularFunctionN-acetyltransferase activity

CREBBP EP300

1.97e-0378172GO:0008080
GeneOntologyMolecularFunctiondamaged DNA binding

CREBBP EP300

2.28e-0384172GO:0003684
GeneOntologyMolecularFunctionSMAD binding

CREBBP EP300

2.39e-0386172GO:0046332
GeneOntologyMolecularFunctionchromatin binding

ARID1A CREBBP NCOA6 EP300

3.01e-03739174GO:0003682
GeneOntologyMolecularFunctionN-acyltransferase activity

CREBBP EP300

3.34e-03102172GO:0016410
GeneOntologyMolecularFunctionacetyltransferase activity

CREBBP EP300

3.47e-03104172GO:0016407
GeneOntologyMolecularFunctiontranscription coregulator binding

CREBBP EP300

6.20e-03140172GO:0001221
GeneOntologyMolecularFunctionchromatin DNA binding

CREBBP EP300

8.71e-03167172GO:0031490
GeneOntologyMolecularFunctionhistone modifying activity

CREBBP EP300

1.59e-02229172GO:0140993
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

CREBBP EP300

1.71e-02238172GO:0016747
GeneOntologyMolecularFunctionmRNA 3'-UTR binding

TIA1 KHSRP

2.26e-02276172GO:0003730
GeneOntologyBiologicalProcessDNA-templated transcription initiation

ARID1A MED15 GTF2A1 NCOA6 EP300

9.36e-07231175GO:0006352
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

CREBBP TSC22D1 EP300

2.99e-0635173GO:1903846
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

CREBBP TSC22D1 EP300

2.99e-0635173GO:0030511
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

3.83e-064172GO:0018076
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase II promoter

ARID1A MED15 GTF2A1 EP300

1.39e-05186174GO:0006367
GeneOntologyBiologicalProcesscellular response to heat

CREBBP EP300 ARPP21

3.81e-0581173GO:0034605
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

MED15 ZNF462 CREBBP GTF2A1 NCOA6 TSC22D1 EP300

6.63e-051390177GO:0045944
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

CREBBP EP300

7.62e-0516172GO:0006474
GeneOntologyBiologicalProcessregulation of cellular response to heat

CREBBP EP300

7.62e-0516172GO:1900034
GeneOntologyBiologicalProcessprotein-DNA complex organization

ARID1A MED15 ZNF462 CREBBP GTF2A1 EP300

9.93e-05999176GO:0071824
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

CREBBP TSC22D1 EP300

1.08e-04115173GO:0090100
GeneOntologyBiologicalProcessresponse to heat

CREBBP EP300 ARPP21

1.26e-04121173GO:0009408
GeneOntologyBiologicalProcessstimulatory C-type lectin receptor signaling pathway

CREBBP EP300

1.60e-0423172GO:0002223
GeneOntologyBiologicalProcesscellular response to lectin

CREBBP EP300

1.60e-0423172GO:1990858
GeneOntologyBiologicalProcessresponse to lectin

CREBBP EP300

1.60e-0423172GO:1990840
GeneOntologyBiologicalProcesspeptidyl-lysine acetylation

CREBBP EP300

2.39e-0428172GO:0018394
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

CREBBP EP300

2.56e-0429172GO:0031365
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

CREBBP TSC22D1 EP300

4.90e-04192173GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

CREBBP TSC22D1 EP300

5.13e-04195173GO:1903844
GeneOntologyBiologicalProcessface morphogenesis

CREBBP EP300

5.14e-0441172GO:0060325
GeneOntologyBiologicalProcessplacenta blood vessel development

ARID1A NCOA6

5.93e-0444172GO:0060674
GeneOntologyBiologicalProcessresponse to temperature stimulus

CREBBP EP300 ARPP21

6.19e-04208173GO:0009266
GeneOntologyBiologicalProcesshead morphogenesis

CREBBP EP300

7.05e-0448172GO:0060323
GeneOntologyBiologicalProcessandrogen receptor signaling pathway

ARID1A EP300

7.96e-0451172GO:0030521
GeneOntologyBiologicalProcessstem cell population maintenance

ARID1A MED15 CREBBP

9.04e-04237173GO:0019827
GeneOntologyBiologicalProcessprotein destabilization

CREBBP EP300

9.59e-0456172GO:0031648
GeneOntologyBiologicalProcessmaintenance of cell number

ARID1A MED15 CREBBP

9.60e-04242173GO:0098727
GeneOntologyBiologicalProcessprotein-DNA complex assembly

MED15 GTF2A1 EP300

1.04e-03249173GO:0065004
GeneOntologyBiologicalProcessface development

CREBBP EP300

1.21e-0363172GO:0060324
GeneOntologyBiologicalProcessbody morphogenesis

CREBBP EP300

1.25e-0364172GO:0010171
GeneOntologyBiologicalProcesstranscription initiation-coupled chromatin remodeling

ARID1A EP300

1.29e-0365172GO:0045815
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

CREBBP TSC22D1 EP300

1.40e-03276173GO:0007179
GeneOntologyBiologicalProcessprotein acetylation

CREBBP EP300

1.41e-0368172GO:0006473
GeneOntologyBiologicalProcesspositive regulation of gene expression, epigenetic

ARID1A EP300

1.41e-0368172GO:0141137
GeneOntologyBiologicalProcesspositive regulation of transcription initiation by RNA polymerase II

MED15 GTF2A1

1.49e-0370172GO:0060261
GeneOntologyBiologicalProcessRNA polymerase II preinitiation complex assembly

MED15 GTF2A1

1.54e-0371172GO:0051123
GeneOntologyBiologicalProcesspositive regulation of DNA-templated transcription initiation

MED15 GTF2A1

1.80e-0377172GO:2000144
GeneOntologyBiologicalProcessinnate immune response-activating signaling pathway

NEK7 CREBBP EP300

1.99e-03312173GO:0002758
GeneOntologyBiologicalProcessregulation of transcription initiation by RNA polymerase II

MED15 GTF2A1

1.99e-0381172GO:0060260
GeneOntologyBiologicalProcesstranscription preinitiation complex assembly

MED15 GTF2A1

2.19e-0385172GO:0070897
GeneOntologyBiologicalProcessactivation of innate immune response

NEK7 CREBBP EP300

2.40e-03333173GO:0002218
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

ARID1A NEK7 CREBBP

2.40e-03333173GO:0051054
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

CREBBP TSC22D1 EP300

2.46e-03336173GO:0071560
GeneOntologyBiologicalProcessregulation of DNA-templated transcription initiation

MED15 GTF2A1

2.51e-0391172GO:2000142
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

CREBBP TSC22D1 EP300

2.61e-03343173GO:0071559
GeneOntologyBiologicalProcesspositive regulation of programmed cell death

TIA1 PHLDA1 TSC22D1 EP300

2.68e-03739174GO:0043068
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

CREBBP TSC22D1 EP300

2.69e-03347173GO:0090092
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair

ARID1A CREBBP

2.73e-0395172GO:2000781
GeneOntologyBiologicalProcessembryo implantation

ARID1A UBE2Q1

2.84e-0397172GO:0007566
GeneOntologyBiologicalProcesscellular response to UV

CREBBP EP300

2.84e-0397172GO:0034644
GeneOntologyCellularComponenttranscription regulator complex

MED15 CREBBP GTF2A1 NCOA6 EP300

8.62e-05596175GO:0005667
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

MED15 CREBBP GTF2A1

1.29e-03272173GO:0090575
GeneOntologyCellularComponenthistone acetyltransferase complex

CREBBP EP300

2.60e-0394172GO:0000123
GeneOntologyCellularComponentcytoplasmic stress granule

TIA1 KHSRP

2.71e-0396172GO:0010494
GeneOntologyCellularComponentprotein acetyltransferase complex

CREBBP EP300

3.18e-03104172GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

CREBBP EP300

3.48e-03109172GO:1902493
GeneOntologyCellularComponentnuclear protein-containing complex

ARID1A MED15 CREBBP GTF2A1 NCOA6

3.91e-031377175GO:0140513
GeneOntologyCellularComponenttransferase complex

CREBBP GTF2A1 NCOA6 EP300

6.58e-03963174GO:1990234
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

7.71e-07252HP:0034227
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

7.71e-07252HP:0008107
HumanPhenoHigh axial triradius

CREBBP EP300

7.71e-07252HP:0001042
HumanPhenoHumoral immunodeficiency

CREBBP EP300

2.31e-06352HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

2.31e-06352HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

2.31e-06352HP:0005895
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

2.31e-06352HP:0008752
HumanPhenoPhobia

CREBBP EP300

2.31e-06352HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

2.31e-06352HP:0000756
HumanPhenoTrichiasis

CREBBP EP300

4.62e-06452HP:0001128
HumanPhenoWidened distal phalanges

CREBBP EP300

4.62e-06452HP:0006200
HumanPhenoVisceral hemangioma

CREBBP EP300

4.62e-06452HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

4.62e-06452HP:0011087
HumanPhenoVascular ring

CREBBP EP300

4.62e-06452HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

4.62e-06452HP:0031207
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

7.70e-06552HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

7.70e-06552HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

7.70e-06552HP:0030421
HumanPhenoLarge foramen magnum

CREBBP EP300

1.15e-05652HP:0002700
HumanPhenoDeviated nasal septum

CREBBP EP300

1.62e-05752HP:0004411
HumanPhenoPilomatrixoma

CREBBP EP300

2.77e-05952HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

2.77e-05952HP:0002341
HumanPhenoFrontal hirsutism

CREBBP EP300

3.46e-051052HP:0011335
HumanPhenoObstructive sleep apnea

ZNF462 CREBBP EP300

3.51e-057953HP:0002870
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

4.22e-051152HP:0031251
HumanPhenoFacial grimacing

CREBBP EP300

5.99e-051352HP:0000273
HumanPhenoKeloids

CREBBP EP300

5.99e-051352HP:0010562
HumanPhenoSandal gap

ARID1A CREBBP EP300

6.31e-059653HP:0001852
HumanPhenoParietal foramina

CREBBP EP300

6.98e-051452HP:0002697
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

6.98e-051452HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

6.98e-051452HP:0012304
HumanPhenoSocial and occupational deterioration

CREBBP EP300

8.05e-051552HP:0007086
HumanPhenoDuplication of phalanx of toe

CREBBP EP300

8.05e-051552HP:0010181
HumanPhenoSquare face

CREBBP EP300

9.20e-051652HP:0000321
HumanPhenoPremature thelarche

CREBBP EP300

1.04e-041752HP:0010314
HumanPhenoFacial hirsutism

CREBBP EP300

1.17e-041852HP:0009937
HumanPhenoSkin appendage neoplasm

CREBBP EP300

1.17e-041852HP:0012842
HumanPhenoBicuspid aortic valve

ZNF462 CREBBP EP300

1.20e-0411953HP:0001647
HumanPhenoAgenesis of corpus callosum

ARID1A ZNF462 CREBBP EP300

1.22e-0436554HP:0001274
HumanPhenoAbnormal aortic valve cusp morphology

ZNF462 CREBBP EP300

1.26e-0412153HP:0031567
HumanPhenoAbsent earlobe

CREBBP EP300

1.45e-042052HP:0000387
HumanPhenoAbnormal lateral ventricle morphology

ZNF462 CREBBP EP300

1.53e-0412953HP:0030047
HumanPhenoLong eyelashes

ARID1A CREBBP EP300

1.53e-0412953HP:0000527
HumanPhenoLocalized hirsutism

CREBBP EP300

1.61e-042152HP:0009889
HumanPhenoDeep plantar creases

CREBBP EP300

1.61e-042152HP:0001869
HumanPhenoCorneal scarring

CREBBP EP300

1.61e-042152HP:0000559
HumanPhenoDysplastic corpus callosum

ARID1A ZNF462 CREBBP EP300

1.67e-0439554HP:0006989
HumanPhenoAbnormal foramen magnum morphology

CREBBP EP300

1.93e-042352HP:0002699
HumanPhenoAgenesis of permanent teeth

CREBBP EP300

1.93e-042352HP:0006349
HumanPhenoNeoplasm of the liver

ARID1A CREBBP EP300

1.95e-0414053HP:0002896
HumanPhenoSimple ear

CREBBP EP300

2.11e-042452HP:0020206
HumanPhenoBroad hallux phalanx

CREBBP EP300

2.11e-042452HP:0010059
HumanPhenoLow anterior hairline

ARID1A CREBBP EP300

2.26e-0414753HP:0000294
HumanPhenoShawl scrotum

CREBBP EP300

2.29e-042552HP:0000049
HumanPhenoMinor feet anomalies

CREBBP EP300

2.48e-042652HP:0010613
HumanPhenoAbnormal feet morphology

CREBBP EP300

2.48e-042652HP:0010611
HumanPhenoPhonophobia

CREBBP EP300

2.48e-042652HP:0002183
HumanPhenoPerimembranous ventricular septal defect

CREBBP EP300

2.48e-042652HP:0011682
HumanPhenoThick eyebrow

ARID1A CREBBP EP300

2.59e-0415453HP:0000574
HumanPhenoFlared iliac wing

CREBBP EP300

2.68e-042752HP:0002869
HumanPhenoBroad distal phalanx of finger

CREBBP EP300

2.68e-042752HP:0009836
HumanPhenoShort columella

CREBBP EP300

3.10e-042952HP:0002000
HumanPhenoAbnormal parietal bone morphology

CREBBP EP300

3.10e-042952HP:0002696
HumanPhenoBroad eyebrow

CREBBP EP300

3.10e-042952HP:0011229
HumanPhenoAbnormality of upper lip vermillion

ARID1A ZNF462 CREBBP EP300

3.16e-0446454HP:0011339
HumanPhenoAvascular necrosis of the capital femoral epiphysis

CREBBP EP300

3.32e-043052HP:0005743
HumanPhenoAbnormal epididymis morphology

CREBBP EP300

3.32e-043052HP:0009714
HumanPhenoPreaxial foot polydactyly

CREBBP EP300

3.32e-043052HP:0001841
HumanPhenoSleep apnea

ZNF462 CREBBP EP300

3.36e-0416853HP:0010535
HumanPhenoSleep-related breathing disorders

ZNF462 CREBBP EP300

3.42e-0416953HP:5200283
HumanPhenoHypoplastic iliac wing

CREBBP EP300

3.54e-043152HP:0002866
HumanPhenoAbnormal distal phalanx morphology of finger

ARID1A CREBBP EP300

3.72e-0417453HP:0009832
HumanPhenoFrontal upsweep of hair

CREBBP EP300

4.02e-043352HP:0002236
HumanPhenoSyringomyelia

CREBBP EP300

4.02e-043352HP:0003396
HumanPhenoAbnormal branching pattern of the aortic arch

CREBBP EP300

4.02e-043352HP:0011587
HumanPhenoAspiration

CREBBP EP300

4.27e-043452HP:0002835
HumanPhenoAbnormality of the helix

ZNF462 CREBBP EP300

4.32e-0418353HP:0000380
HumanPhenoAbnormal number of permanent teeth

CREBBP EP300

4.53e-043552HP:0011044
HumanPhenoAbnormal 5th finger morphology

ARID1A ZNF462 CREBBP EP300

4.54e-0450954HP:0004207
HumanPhenoVentricular septal defect

ARID1A ZNF462 CREBBP EP300

4.58e-0451054HP:0001629
HumanPhenoHydrocele testis

CREBBP EP300

4.79e-043652HP:0000034
HumanPhenoDisturbance of facial expression

CREBBP EP300

4.79e-043652HP:0005324
HumanPhenoAbnormality of the distal phalanx of the thumb

CREBBP EP300

4.79e-043652HP:0009617
HumanPhenoNasolacrimal duct obstruction

CREBBP EP300

4.79e-043652HP:0000579
HumanPhenoAbnormal ventricular septum morphology

ARID1A ZNF462 CREBBP EP300

4.97e-0452154HP:0010438
HumanPhenoAuditory sensitivity

CREBBP EP300

5.06e-043752HP:0025112
HumanPhenoAccessory spleen

CREBBP EP300

5.06e-043752HP:0001747
HumanPhenoAuditory hypersensitivity

CREBBP EP300

5.06e-043752HP:5200060
HumanPhenoNasogastric tube feeding in infancy

CREBBP EP300

5.06e-043752HP:0011470
HumanPhenoCongenital malformation of the great arteries

ARID1A ZNF462 CREBBP EP300

5.28e-0452954HP:0011603
HumanPhenoNatal tooth

CREBBP EP300

5.34e-043852HP:0000695
HumanPhenoCapillary hemangioma

CREBBP EP300

5.63e-043952HP:0005306
HumanPhenoCellular immunodeficiency

CREBBP EP300

5.63e-043952HP:0005374
HumanPhenoPoor coordination

CREBBP EP300

5.63e-043952HP:0002370
HumanPhenoHighly arched eyebrow

ZNF462 CREBBP EP300

6.14e-0420653HP:0002553
HumanPhenoAbnormal hair whorl

CREBBP EP300

6.53e-044252HP:0010721
HumanPhenoAbnormal helix morphology

ZNF462 CREBBP EP300

6.68e-0421253HP:0011039
HumanPhenoJuvenile aseptic necrosis

CREBBP EP300

6.85e-044352HP:0100323
HumanPhenoTube feeding

ZNF462 CREBBP EP300

6.96e-0421553HP:0033454
HumanPhenoSingle transverse palmar crease

ZNF462 CREBBP EP300

6.96e-0421553HP:0000954
MousePhenothin myocardium compact layer

CREBBP NCOA6 EP300

7.19e-0646123MP:0004057
MousePhenoprenatal lethality prior to heart atrial septation, incomplete penetrance

UBE2Q1 NEK7 CREBBP NCOA6 EP300

1.42e-05410125MP:0031660
MousePhenoembryonic lethality, incomplete penetrance

UBE2Q1 NEK7 CREBBP NCOA6 EP300

1.42e-05410125MP:0011102
MousePhenoabnormal myocardium compact layer morphology

CREBBP NCOA6 EP300

2.24e-0567123MP:0004056
MousePhenoventricle myocardium hypoplasia

CREBBP NCOA6 EP300

2.67e-0571123MP:0010502
MousePhenomyocardium hypoplasia

CREBBP NCOA6 EP300

4.75e-0586123MP:0010500
MousePhenoembryonic lethality during organogenesis, incomplete penetrance

NEK7 CREBBP NCOA6 EP300

5.79e-05268124MP:0011108
MousePhenoventricular hypoplasia

CREBBP NCOA6 EP300

7.24e-0599123MP:0000279
MousePhenoheart hypoplasia

CREBBP NCOA6 EP300

8.14e-05103123MP:0002740
MousePhenoabnormal epicardium morphology

NCOA6 EP300

9.12e-0517122MP:0003057
MousePhenopericardial effusion

ARID1A NCOA6 EP300

1.02e-04111123MP:0005312
MousePhenoabnormal ventricle myocardium morphology

CREBBP NCOA6 EP300

1.16e-04116123MP:0010499
MousePhenosmall heart

CREBBP NCOA6 TSC22D1 EP300

1.17e-04321124MP:0002188
MousePhenothin ventricle myocardium compact layer

CREBBP EP300

1.27e-0420122MP:0010556
MousePhenoabsent myocardial trabeculae

ARID1A EP300

1.55e-0422122MP:0000293
MousePhenolethality during fetal growth through weaning, incomplete penetrance

TIA1 NEK7 CREBBP GTF2A1 NCOA6 EP300

1.61e-041124126MP:0011112
MousePhenoperinatal lethality

ARID1A NEK7 CREBBP GTF2A1 NCOA6 EP300

1.66e-041130126MP:0002081
MousePhenoabnormal myocardial trabeculae morphology

ARID1A NCOA6 EP300

2.20e-04144123MP:0002189
MousePhenoprenatal lethality, incomplete penetrance

UBE2Q1 NEK7 CREBBP NCOA6 EP300

2.49e-04747125MP:0011101
MousePhenoabnormal spongiotrophoblast size

ARID1A NCOA6

2.52e-0428122MP:0012097
MousePhenoeffusion

ARID1A NCOA6 EP300

2.58e-04152123MP:0021205
MousePhenoabnormal myocardium layer morphology

ARID1A CREBBP NCOA6 EP300

3.11e-04414124MP:0005329
MousePhenoabnormal heart layer morphology

ARID1A CREBBP NCOA6 EP300

3.34e-04422124MP:0010545
MousePhenolethality throughout fetal growth and development

NEK7 CREBBP NCOA6 EP300

3.75e-04435124MP:0006208
MousePhenooligodactyly

CREBBP NCOA6

4.92e-0439122MP:0000565
MousePhenoembryonic lethality during organogenesis

ARID1A NEK7 CREBBP NCOA6 EP300

5.22e-04876125MP:0006207
MousePhenoabnormal cardiac muscle tissue morphology

ARID1A CREBBP NCOA6 EP300

5.85e-04489124MP:0010630
MousePhenolethality throughout fetal growth and development, incomplete penetrance

NEK7 CREBBP EP300

6.47e-04208123MP:0011109
MousePhenoperinatal lethality, incomplete penetrance

NEK7 CREBBP GTF2A1 NCOA6

6.51e-04503124MP:0011090
MousePhenoincreased megakaryocyte cell number

CREBBP EP300

6.55e-0445122MP:0008254
MousePhenoabnormal embryo size

ARID1A ZNF462 CREBBP NCOA6 EP300

7.81e-04956125MP:0001697
MousePhenoabnormal pericardium morphology

ARID1A NCOA6 EP300

8.13e-04225123MP:0000288
MousePhenoopen neural tube

ARID1A CREBBP EP300

8.24e-04226123MP:0000929
MousePhenoabnormal vascular development

ARID1A CREBBP NCOA6 EP300

8.63e-04542124MP:0000259
MousePhenodecreased birth body size

NEK7 ZNF462 NCOA6

8.89e-04232123MP:0009703
MousePhenoabnormal vitelline vasculature morphology

CREBBP NCOA6 EP300

9.22e-04235123MP:0003229
MousePhenoabnormal vasculogenesis

CREBBP EP300

9.43e-0454122MP:0001622
MousePhenoabnormal birth body size

NEK7 ZNF462 NCOA6

9.45e-04237123MP:0009701
MousePhenoventricular septal defect

ARID1A CREBBP EP300

1.25e-03261123MP:0010402
MousePhenoabnormal adipose tissue amount

ZNF462 CREBBP GTF2A1 NCOA6 KHSRP

1.35e-031077125MP:0005452
MousePhenoabnormal prenatal body size

ARID1A ZNF462 CREBBP NCOA6 EP300

1.58e-031116125MP:0010866
MousePhenoabnormal spongiotrophoblast layer morphology

ARID1A NCOA6

1.67e-0372122MP:0004255
MousePhenoincreased grooming behavior

ZNF462 CREBBP

1.76e-0374122MP:0001441
MousePhenodecreased embryo size

ARID1A CREBBP NCOA6 EP300

1.79e-03659124MP:0001698
MousePhenoabnormal hematopoietic precursor cell morphology

ARID1A CREBBP NCOA6

1.85e-03299123MP:0013707
MousePhenopostnatal lethality, incomplete penetrance

TIA1 NEK7 CREBBP EP300

1.89e-03669124MP:0011086
MousePhenoabnormal trabecula carnea morphology

NCOA6 EP300

1.96e-0378122MP:0004067
MousePhenoabnormal placenta junctional zone morphology

ARID1A NCOA6

2.06e-0380122MP:0008957
MousePhenoembryonic lethality during organogenesis, complete penetrance

ARID1A CREBBP NCOA6 EP300

2.23e-03700124MP:0011098
MousePhenothin myocardium

NCOA6 EP300

2.32e-0385122MP:0002652
MousePhenoabnormal megakaryocyte morphology

CREBBP EP300

2.37e-0386122MP:0002417
MousePhenoatrial septal defect

CREBBP EP300

2.48e-0388122MP:0010403
MousePhenoperimembraneous ventricular septal defect

CREBBP EP300

2.71e-0392122MP:0010418
MousePhenoabnormal interventricular septum morphology

ARID1A CREBBP EP300

2.71e-03342123MP:0000281
MousePhenoabnormal interventricular septum membranous part morphology

CREBBP EP300

2.77e-0393122MP:0008823
MousePhenoembryonic growth arrest

ARID1A CREBBP EP300

2.80e-03346123MP:0001730
MousePhenoabnormal embryonic growth/weight/body size

ARID1A ZNF462 CREBBP NCOA6 EP300

3.08e-031295125MP:0002088
MousePhenoabnormal bone marrow hematopoietic cell morphology

CREBBP EP300

3.32e-03102122MP:0013660
MousePhenoabnormal heart development

CREBBP NCOA6 EP300

3.44e-03372123MP:0000267
MousePhenoabnormal heart ventricle morphology

ARID1A CREBBP NCOA6 EP300

3.53e-03793124MP:0005294
MousePhenoabnormal neural tube closure

ARID1A CREBBP EP300

3.60e-03378123MP:0003720
MousePhenoabnormal interatrial septum morphology

CREBBP EP300

3.64e-03107122MP:0000282
MousePhenoabnormal cardiovascular development

ARID1A CREBBP NCOA6 EP300

3.67e-03802124MP:0002925
MousePhenoabnormal adipose tissue morphology

ZNF462 CREBBP GTF2A1 NCOA6 KHSRP

3.83e-031361125MP:0000003
MousePhenopale yolk sac

ARID1A CREBBP

3.85e-03110122MP:0001722
MousePhenoabnormal heart septum morphology

ARID1A CREBBP EP300

3.87e-03388123MP:0006113
MousePhenoabnormal hematopoietic stem cell morphology

ARID1A CREBBP

3.98e-03112122MP:0004808
MousePhenoabnormal fluid regulation

ARID1A ZNF462 NCOA6 EP300

4.09e-03826124MP:0001784
MousePhenoadipose tissue phenotype

ZNF462 CREBBP GTF2A1 NCOA6 KHSRP

4.11e-031383125MP:0005375
MousePhenodecreased birth weight

NEK7 NCOA6

4.63e-03121122MP:0009674
MousePhenoabnormal birth weight

NEK7 NCOA6

4.78e-03123122MP:0009672
MousePhenodecreased thymocyte number

CREBBP EP300

5.09e-03127122MP:0000715
MousePhenodecreased fibroblast proliferation

NCOA6 EP300

5.25e-03129122MP:0011704
MousePhenoabnormal prenatal growth/weight/body size

ARID1A ZNF462 CREBBP NCOA6 EP300

5.74e-031493125MP:0004196
MousePhenoabnormal extraembryonic tissue morphology

ARID1A CREBBP NCOA6 EP300

5.74e-03908124MP:0002086
MousePhenoabnormal grooming behavior

ZNF462 CREBBP

5.90e-03137122MP:0001440
MousePhenothin ventricular wall

NCOA6 EP300

5.98e-03138122MP:0000280
Domain-

CREBBP EP300

7.80e-0721721.10.246.20
Domainzf-TAZ

CREBBP EP300

7.80e-072172PF02135
DomainZF_TAZ

CREBBP EP300

7.80e-072172PS50134
Domain-

CREBBP EP300

7.80e-0721721.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

7.80e-072172IPR010303
DomainKAT11

CREBBP EP300

7.80e-072172SM01250
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

7.80e-072172IPR014744
DomainHAT_KAT11

CREBBP EP300

7.80e-072172PF08214
Domain-

CREBBP EP300

7.80e-0721721.10.1630.10
DomainKIX

CREBBP EP300

7.80e-072172PS50952
DomainZnf_TAZ

CREBBP EP300

7.80e-072172IPR000197
DomainKIX_dom

CREBBP EP300

7.80e-072172IPR003101
DomainCreb_binding

CREBBP EP300

7.80e-072172PF09030
DomainKIX

CREBBP EP300

7.80e-072172PF02172
DomainZnF_TAZ

CREBBP EP300

7.80e-072172SM00551
DomainCBP_P300_HAT

CREBBP EP300

7.80e-072172IPR031162
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

7.80e-072172IPR013178
DomainCBP_P300_HAT

CREBBP EP300

7.80e-072172PS51727
DomainDUF902

CREBBP EP300

7.80e-072172PF06001
DomainSUZ

R3HDM2 ARPP21

4.67e-064172IPR024771
DomainSUZ

R3HDM2 ARPP21

4.67e-064172PS51673
DomainNuc_rcpt_coact

CREBBP EP300

1.17e-056172IPR009110
DomainR3H

R3HDM2 ARPP21

2.80e-059172SM00393
DomainR3H

R3HDM2 ARPP21

4.27e-0511172PS51061
DomainR3H

R3HDM2 ARPP21

4.27e-0511172PF01424
DomainR3H_dom

R3HDM2 ARPP21

4.27e-0511172IPR001374
Domain-

R3HDM2 ARPP21

4.27e-05111723.30.1370.50
DomainZF_ZZ_1

CREBBP EP300

1.18e-0418172PS01357
DomainZF_ZZ_2

CREBBP EP300

1.18e-0418172PS50135
DomainZZ

CREBBP EP300

1.18e-0418172PF00569
DomainZnF_ZZ

CREBBP EP300

1.32e-0419172SM00291
DomainZnf_ZZ

CREBBP EP300

1.32e-0419172IPR000433
DomainBromodomain_CS

CREBBP EP300

2.50e-0426172IPR018359
DomainBROMODOMAIN_1

CREBBP EP300

5.10e-0437172PS00633
DomainBromodomain

CREBBP EP300

5.38e-0438172PF00439
DomainBROMODOMAIN_2

CREBBP EP300

6.26e-0441172PS50014
DomainBROMO

CREBBP EP300

6.57e-0442172SM00297
DomainBromodomain

CREBBP EP300

6.57e-0442172IPR001487
Domain-

CREBBP EP300

6.57e-04421721.20.920.10
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP NCOA6 EP300

6.31e-0718143M26942
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

MED15 CREBBP NCOA6 EP300

1.12e-0684144M1008
PathwayBIOCARTA_VDR_PATHWAY

ARID1A CREBBP EP300

1.19e-0622143MM1370
PathwayBIOCARTA_VDR_PATHWAY

ARID1A CREBBP EP300

1.56e-0624143M13404
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP GTF2A1 EP300

2.00e-0626143M2499
PathwayREACTOME_ADIPOGENESIS

MED15 CREBBP NCOA6 EP300

3.31e-06110144M48259
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

MED15 CREBBP NCOA6 EP300

4.38e-06118144M27316
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

9.14e-065142MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

9.14e-065142M48020
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

9.14e-065142M27228
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

9.14e-065142M48023
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.37e-056142M22062
PathwayREACTOME_HEME_SIGNALING

CREBBP NCOA6 EP300

1.40e-0549143M41832
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.92e-057142MM1573
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

2.56e-058142M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

2.56e-058142M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

2.56e-058142M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

2.56e-058142M46443
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

3.28e-059142M47451
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

ARID1A CREBBP EP300

3.28e-0565143M39682
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

4.10e-0510142M27945
PathwayREACTOME_CIRCADIAN_CLOCK

CREBBP NCOA6 EP300

4.10e-0570143M938
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

5.01e-0511142MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

5.01e-0511142M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

5.01e-0511142M26924
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

6.01e-0512142M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

6.01e-0512142M27765
PathwayBIOCARTA_HSWI_SNF_PATHWAY

ARID1A GTF2A1

6.01e-0512142M22006
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

MED15 CREBBP EP300

6.59e-0582143M2
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

8.28e-0514142M27808
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

9.55e-0515142MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

9.55e-0515142M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

9.55e-0515142MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

9.55e-0515142M953
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.09e-0416142M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.09e-0416142MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.09e-0416142M8516
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

1.09e-0416142M27121
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.09e-0416142M27940
PathwayREACTOME_RSV_HOST_INTERACTIONS

MED15 CREBBP EP300

1.12e-0498143M48247
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.24e-0417142MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

1.24e-0417142M48025
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.55e-0419142M18933
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

1.55e-0419142M46442
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

1.72e-0420142M27881
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

1.90e-0421142M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

1.90e-0421142M27485
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY

MED15 CREBBP EP300

2.04e-04120143M48233
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

2.09e-0422142MM1443
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

CREBBP NCOA6 EP300

2.15e-04122143M29689
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

2.29e-0423142M2821
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

2.71e-0425142M27880
PathwayPID_HDAC_CLASSIII_PATHWAY

CREBBP EP300

2.94e-0426142M32
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

CREBBP NCOA6

3.17e-0427142M26943
PathwayREACTOME_ATTENUATION_PHASE

CREBBP EP300

3.41e-0428142M27254
PathwayWP_KLEEFSTRA_SYNDROME

ARID1A NCOA6

3.66e-0429142M48076
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

CREBBP GTF2A1 EP300

3.87e-04149143M27888
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP EP300

3.92e-0430142M207
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

CREBBP EP300

3.92e-0430142M936
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP EP300

4.47e-0432142M39521
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

CREBBP EP300

5.05e-0434142M39771
PathwayPID_HIF2PATHWAY

CREBBP EP300

5.05e-0434142M44
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

ARID1A EP300

5.05e-0434142MM15531
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

CREBBP EP300

5.35e-0435142M48246
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

ARID1A EP300

5.98e-0437142M27797
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

6.31e-0438142M27757
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CREBBP EP300

6.31e-0438142M27255
PathwayPID_FOXM1_PATHWAY

CREBBP EP300

6.99e-0440142M176
PathwayPID_IFNG_PATHWAY

CREBBP EP300

6.99e-0440142M161
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

CREBBP EP300

7.71e-0442142M17541
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

CREBBP NCOA6

7.71e-0442142M27172
PathwayPID_HNF3A_PATHWAY

CREBBP EP300

8.46e-0444142M285
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

CREBBP EP300

8.46e-0444142M27295
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

CREBBP EP300

9.65e-0447142M7946
PathwayPID_HES_HEY_PATHWAY

CREBBP EP300

1.01e-0348142M288
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

1.01e-0348142M611
PathwayPID_FOXO_PATHWAY

CREBBP EP300

1.05e-0349142M136
PathwayREACTOME_SIGNALING_BY_NOTCH3

CREBBP EP300

1.05e-0349142M618
PathwayREACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

CREBBP NCOA6 EP300

1.05e-03210143M41836
PathwayBIOCARTA_PPARA_PATHWAY

CREBBP EP300

1.18e-0352142M2404
PathwayREACTOME_ESR_MEDIATED_SIGNALING

CREBBP GTF2A1 EP300

1.20e-03220143M27794
PathwayPID_NFAT_3PATHWAY

CREBBP EP300

1.23e-0353142M113
PathwayPID_AR_TF_PATHWAY

CREBBP EP300

1.23e-0353142M151
PathwayWP_TGFBETA_SIGNALING_PATHWAY

CREBBP EP300

1.23e-0353142MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

CREBBP EP300

1.32e-0355142M39351
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

CREBBP NCOA6

1.32e-0355142M27145
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

CREBBP NCOA6

1.32e-0355142M27001
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

CREBBP EP300

1.47e-0358142M29616
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

ARID1A CREBBP EP300

1.49e-03237143M27786
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

CREBBP EP300

1.52e-0359142M39886
PathwayPID_P53_REGULATION_PATHWAY

CREBBP EP300

1.52e-0359142M261
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

CREBBP NCOA6

1.57e-0360142M41830
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

ARID1A MED15 CREBBP NCOA6 TSC22D1 EP300

1.59e-031432146M509
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

GTF2A1 EP300

1.73e-0363142MM15613
PathwayREACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA

CREBBP EP300

1.78e-0364142M27046
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

ARID1A NCOA6 EP300

1.82e-03254143M27131
PathwayPID_RB_1PATHWAY

CREBBP EP300

1.84e-0365142M279
PathwayPID_HIF1_TFPATHWAY

CREBBP EP300

1.89e-0366142M255
PathwayPID_HDAC_CLASSI_PATHWAY

CREBBP EP300

1.89e-0366142M101
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

CREBBP EP300

1.89e-0366142M27938
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

MED15 CREBBP GTF2A1 R3HDM2 EP300 SPATS2L

7.50e-1115217638360978
Pubmed

Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation.

CREBBP NCOA6 EP300

9.69e-10517311912212
Pubmed

Interaction network of human early embryonic transcription factors.

ARID1A MED15 ZNF462 CREBBP NCOA6 EP300

1.14e-0835117638297188
Pubmed

Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation.

CREBBP GTF2A1 EP300

1.60e-081117310454579
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

CREBBP NCOA6 EP300

2.13e-081217312189208
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

ARID1A MED15 CREBBP GTF2A1 NCOA6 EP300

3.55e-0842517624999758
Pubmed

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

CREBBP GTF2A1 NCOA6

4.40e-081517310567404
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

ARID1A MED15 PHLDA1 CREBBP EP300 KHSRP

5.18e-0845317629656893
Pubmed

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.

CREBBP NCOA6 EP300

6.57e-081717328291835
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

CREBBP NCOA6 EP300

1.10e-072017311877444
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

CREBBP NCOA6 EP300

1.28e-072117319596656
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ARID1A MED15 CREBBP NCOA6 EP300 KHSRP

1.61e-0754917638280479
Pubmed

Composite co-activator ARC mediates chromatin-directed transcriptional activation.

MED15 CREBBP EP300

1.71e-072317310235267
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

2.25e-07217227881875
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

2.25e-07217211963968
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

2.25e-07217234845315
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

2.25e-07217234813504
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

2.25e-07217219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

2.25e-07217215860545
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

2.25e-0721729528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

2.25e-07217212696060
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

2.25e-07217229460469
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

2.25e-07217220301699
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

2.25e-07217224551300
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

2.25e-07217236109165
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

2.25e-07217224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

2.25e-07217237816914
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

2.25e-07217212242694
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

2.25e-07217233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

2.25e-0721729018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

2.25e-07217224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

2.25e-07217230135524
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

2.25e-07217211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

2.25e-07217210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

2.25e-07217231182547
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

2.25e-07217235502657
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

2.25e-07217239287984
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

2.25e-07217230635043
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

2.25e-07217231898871
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

2.25e-07217216596650
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

2.25e-07217227648933
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

2.25e-07217230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

2.25e-07217227881443
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

2.25e-07217229217654
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

2.25e-07217219272189
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

2.25e-07217210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

2.25e-07217237314181
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

2.25e-07217220717166
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

2.25e-07217212397173
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

2.25e-07217210049825
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

2.25e-07217215641773
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

2.25e-07217232690000
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

2.25e-0721729733868
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

2.25e-07217230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

2.25e-07217221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

2.25e-0721729811832
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

2.25e-07217227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

2.25e-07217229170789
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

2.25e-07217224089570
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

2.25e-07217225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

2.25e-07217211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

2.25e-07217221555743
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

2.25e-07217233063428
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

2.25e-07217212646247
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

2.25e-07217234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

2.25e-07217222177454
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

2.25e-07217215706485
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

2.25e-07217232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

2.25e-07217219822209
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

2.25e-07217239266679
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

2.25e-07217224522976
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

2.25e-07217222303793
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

2.25e-07217211867645
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

2.25e-07217221847097
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

2.25e-07217234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

2.25e-07217234019788
Pubmed

Transcriptional coactivators CBP and p300 cooperatively enhance HNF-1alpha-mediated expression of the albumin gene in hepatocytes.

CREBBP EP300

6.74e-07317215598887
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

CREBBP EP300

6.74e-07317214716005
Pubmed

The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment.

CREBBP EP300

6.74e-07317225689462
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

6.74e-07317218070920
Pubmed

Acetylation of beta-catenin by CREB-binding protein (CBP).

CREBBP EP300

6.74e-07317211973335
Pubmed

Coactivator ASC-2 mediates heat shock factor 1-mediated transactivation dependent on heat shock.

CREBBP NCOA6

6.74e-07317214960326
Pubmed

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.

CREBBP EP300

6.74e-07317221967847
Pubmed

Synergistic activation of transcription by CBP and p53.

CREBBP EP300

6.74e-0731729194564
Pubmed

Regulation of NF-kappaB action by reversible acetylation.

CREBBP EP300

6.74e-07317215171256
Pubmed

p300/CBP acts as a coactivator of the cone-rod homeobox transcription factor.

CREBBP EP300

6.74e-07317210708567
Pubmed

Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development.

CREBBP EP300

6.74e-07317216428436
Pubmed

Histone acetyl transferases CBP and p300 are necessary for maintenance of renin cell identity and transformation of smooth muscle cells to the renin phenotype.

CREBBP EP300

6.74e-07317222523253
Pubmed

Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.

CREBBP EP300

6.74e-07317211823864
Pubmed

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.

CREBBP EP300

6.74e-07317219252086
Pubmed

An essential role for p300/CBP in the cellular response to hypoxia.

CREBBP EP300

6.74e-0731728917528
Pubmed

Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8.

CREBBP EP300

6.74e-07317219948376
Pubmed

E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus.

CREBBP EP300

6.74e-07317222544934
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

CREBBP EP300

6.74e-07317227903646
Pubmed

Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.

CREBBP EP300

6.74e-07317210673499
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

6.74e-07317212748286
Pubmed

Identification of a novel SNF2/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein.

CREBBP EP300

6.74e-07317210347196
Pubmed

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.

CREBBP EP300

6.74e-07317210075656
Pubmed

CCAAT/Enhancer-binding protein beta DNA binding is auto-inhibited by multiple elements that also mediate association with p300/CREB-binding protein (CBP).

CREBBP EP300

6.74e-07317220452968
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

6.74e-07317224340053
InteractionEYA4 interactions

MED15 CREBBP GTF2A1 R3HDM2 EP300 SPATS2L

3.20e-08243176int:EYA4
InteractionNCOA6 interactions

MED15 CREBBP GTF2A1 NCOA6 EP300

1.04e-07145175int:NCOA6
InteractionEGR2 interactions

ARID1A ZNF462 CREBBP NCOA6 EP300

2.36e-07171175int:EGR2
InteractionAR interactions

ARID1A MED15 ZNF462 CREBBP NCOA6 EP300 KHSRP SPATS2L

5.47e-07992178int:AR
InteractionFEV interactions

ARID1A ZNF462 CREBBP NCOA6 EP300

5.54e-07203175int:FEV
InteractionSOX9 interactions

ARID1A CREBBP NCOA6 EP300

1.14e-0697174int:SOX9
InteractionSMAD1 interactions

ARID1A MED15 CREBBP NCOA6 EP300

1.34e-06243175int:SMAD1
InteractionING1 interactions

ARID1A CREBBP GTF2A1 EP300

1.46e-06103174int:ING1
InteractionCRX interactions

ARID1A MED15 ZNF462 CREBBP EP300

1.67e-06254175int:CRX
InteractionTBXT interactions

ARID1A CREBBP NCOA6 EP300

2.34e-06116174int:TBXT
InteractionHNF4A interactions

ARID1A ZNF462 CREBBP NCOA6 EP300

2.47e-06275175int:HNF4A
InteractionTP53BP1 interactions

ARID1A MED15 CREBBP NCOA6 EP300 KHSRP

3.21e-06533176int:TP53BP1
InteractionE2F5 interactions

ARID1A CREBBP EP300

3.50e-0636173int:E2F5
InteractionKLF1 interactions

ARID1A CREBBP EP300

3.81e-0637173int:KLF1
InteractionFOS interactions

ARID1A CREBBP NCOA6 EP300 KHSRP

4.57e-06312175int:FOS
InteractionEWSR1 interactions

TIA1 ARID1A MED15 CREBBP GTF2A1 NCOA6 EP300

4.75e-06906177int:EWSR1
InteractionNCOA1 interactions

ARID1A CREBBP NCOA6 EP300

5.85e-06146174int:NCOA1
InteractionPAX6 interactions

ARID1A ZNF462 CREBBP NCOA6 EP300

9.94e-06366175int:PAX6
InteractionNFATC1 interactions

ARID1A NEK7 CREBBP EP300

1.02e-05168174int:NFATC1
InteractionTLX1 interactions

ARID1A ZNF462 CREBBP EP300

1.20e-05175174int:TLX1
InteractionTEAD1 interactions

ARID1A ZNF462 CREBBP EP300

1.22e-05176174int:TEAD1
InteractionSMAD2 interactions

ARID1A MED15 CREBBP NCOA6 EP300

1.27e-05385175int:SMAD2
InteractionBCL3 interactions

CREBBP GTF2A1 EP300

1.34e-0556173int:BCL3
InteractionTPRX2 interactions

ARID1A CREBBP NCOA6

1.34e-0556173int:TPRX2
InteractionALG13 interactions

TIA1 ARID1A R3HDM2 EP300

1.43e-05183174int:ALG13
InteractionNFIA interactions

ARID1A MED15 CREBBP EP300

1.59e-05188174int:NFIA
InteractionCTBP1 interactions

TIA1 MED15 CREBBP EP300 KHSRP

1.64e-05406175int:CTBP1
InteractionKLF5 interactions

ARID1A CREBBP NCOA6 EP300

1.83e-05195174int:KLF5
InteractionARPP21 interactions

R3HDM2 ARPP21

1.87e-058172int:ARPP21
InteractionWWTR1 interactions

ARID1A CREBBP NCOA6 EP300 KHSRP

1.98e-05422175int:WWTR1
InteractionGATA2 interactions

ARID1A CREBBP NCOA6 EP300

1.99e-05199174int:GATA2
InteractionNUP35 interactions

ARID1A MED15 CREBBP NCOA6 EP300

2.02e-05424175int:NUP35
InteractionTRIP4 interactions

MED15 CREBBP GTF2A1 EP300

2.27e-05206174int:TRIP4
InteractionCNOT3 interactions

MED15 CREBBP R3HDM2 EP300

2.32e-05207174int:CNOT3
InteractionHOXB3 interactions

CREBBP EP300

2.40e-059172int:HOXB3
InteractionARGFX interactions

CREBBP EP300

2.40e-059172int:ARGFX
InteractionGCM1 interactions

ARID1A CREBBP EP300

2.42e-0568173int:GCM1
InteractionETV4 interactions

ARID1A CREBBP EP300

2.52e-0569173int:ETV4
InteractionSMAD3 interactions

ARID1A MED15 CREBBP NCOA6 EP300

2.61e-05447175int:SMAD3
InteractionDDX1 interactions

TIA1 NEK7 R3HDM2 EP300 KHSRP

3.08e-05463175int:DDX1
InteractionRARA interactions

ARID1A CREBBP NCOA6 EP300

3.10e-05223174int:RARA
InteractionERG interactions

ARID1A CREBBP NCOA6 EP300

3.10e-05223174int:ERG
InteractionTGS1 interactions

CREBBP NCOA6 EP300

3.24e-0575173int:TGS1
InteractionNANOG interactions

TIA1 ARID1A ZNF462 EP300 KHSRP

3.70e-05481175int:NANOG
InteractionHNF1A interactions

CREBBP GTF2A1 EP300

3.93e-0580173int:HNF1A
InteractionPPARGC1A interactions

CREBBP NCOA6 EP300

4.24e-0582173int:PPARGC1A
InteractionSOX7 interactions

ARID1A CREBBP EP300

4.24e-0582173int:SOX7
InteractionIRF1 interactions

ARID1A CREBBP EP300

4.39e-0583173int:IRF1
InteractionGSC interactions

ZNF462 CREBBP EP300

5.06e-0587173int:GSC
InteractionTBP interactions

CREBBP GTF2A1 NCOA6 EP300

5.08e-05253174int:TBP
InteractionASCL2 interactions

NCOA6 EP300

5.20e-0513172int:ASCL2
InteractionPCMT1 interactions

TIA1 CREBBP NCOA6 KHSRP

5.31e-05256174int:PCMT1
InteractionN4BP2 interactions

CREBBP R3HDM2 EP300

5.41e-0589173int:N4BP2
InteractionCPSF6 interactions

TIA1 NEK7 CREBBP EP300 KHSRP

5.67e-05526175int:CPSF6
InteractionESRRB interactions

ARID1A MED15 ZNF462 KHSRP

5.82e-05262174int:ESRRB
InteractionFOXI1 interactions

ARID1A CREBBP EP300

5.98e-0592173int:FOXI1
InteractionMED23 interactions

MED15 CREBBP NCOA6 EP300

6.17e-05266174int:MED23
InteractionGRIP1 interactions

CREBBP NCOA6 EP300

6.79e-0596173int:GRIP1
InteractionKLF2 interactions

CREBBP EP300

6.99e-0515172int:KLF2
InteractionSS18L1 interactions

ARID1A CREBBP EP300

7.22e-0598173int:SS18L1
InteractionRBBP5 interactions

ARID1A CREBBP NCOA6 EP300

8.28e-05287174int:RBBP5
InteractionRBBP4 interactions

ARID1A MED15 ZNF462 CREBBP EP300

8.51e-05573175int:RBBP4
InteractionNFYA interactions

CREBBP GTF2A1 EP300

8.86e-05105173int:NFYA
InteractionSOX2 interactions

TIA1 ARID1A ZNF462 NCOA6 EP300 KHSRP SPATS2L

8.89e-051422177int:SOX2
InteractionMAML2 interactions

CREBBP EP300

9.04e-0517172int:MAML2
InteractionFUBP3 interactions

TIA1 R3HDM2 EP300 KHSRP

9.46e-05297174int:FUBP3
InteractionSP7 interactions

ARID1A CREBBP NCOA6 EP300

1.03e-04304174int:SP7
InteractionPAX8 interactions

ARID1A CREBBP EP300

1.05e-04111173int:PAX8
InteractionTHRA interactions

CREBBP NCOA6 EP300

1.05e-04111173int:THRA
InteractionCREBBP interactions

ARID1A PHLDA1 CREBBP NCOA6 EP300

1.05e-04599175int:CREBBP
InteractionPPARG interactions

CREBBP NCOA6 EP300 KHSRP

1.07e-04307174int:PPARG
InteractionKHSRP interactions

TIA1 NEK7 EP300 KHSRP

1.09e-04308174int:KHSRP
InteractionNEUROG1 interactions

CREBBP EP300

1.14e-0419172int:NEUROG1
InteractionSMG7 interactions

ARID1A CREBBP NCOA6 R3HDM2

1.25e-04319174int:SMG7
InteractionSPIB interactions

CREBBP EP300

1.26e-0420172int:SPIB
InteractionDDIT3 interactions

ARID1A CREBBP EP300

1.32e-04120173int:DDIT3
InteractionRUNX1 interactions

ARID1A CREBBP EP300 KHSRP

1.32e-04324174int:RUNX1
InteractionETS1 interactions

ARID1A CREBBP EP300

1.35e-04121173int:ETS1
InteractionCITED4 interactions

CREBBP EP300

1.39e-0421172int:CITED4
InteractionHOXB4 interactions

CREBBP EP300

1.39e-0421172int:HOXB4
InteractionPLAGL1 interactions

CREBBP EP300

1.39e-0421172int:PLAGL1
InteractionKLF13 interactions

CREBBP EP300

1.39e-0421172int:KLF13
InteractionATXN1 interactions

ARID1A MED15 CREBBP GTF2A1 R3HDM2 KHSRP

1.40e-041039176int:ATXN1
InteractionFOXO3 interactions

ARID1A CREBBP EP300

1.45e-04124173int:FOXO3
InteractionPAX7 interactions

ARID1A CREBBP EP300

1.45e-04124173int:PAX7
InteractionFAF1 interactions

CREBBP TSC22D1 EP300 KHSRP

1.49e-04334174int:FAF1
InteractionRUNX2 interactions

MED15 CREBBP EP300

1.52e-04126173int:RUNX2
InteractionVDR interactions

CREBBP NCOA6 EP300

1.56e-04127173int:VDR
InteractionSRCAP interactions

MED15 CREBBP EP300

1.56e-04127173int:SRCAP
InteractionNUP50 interactions

ARID1A GTF2A1 TSC22D1 KHSRP

1.61e-04341174int:NUP50
InteractionFHL1 interactions

NEK7 CREBBP EP300

1.63e-04129173int:FHL1
InteractionBMI1 interactions

TIA1 CREBBP EP300 KHSRP SPATS2L

1.64e-04659175int:BMI1
InteractionPAX9 interactions

ARID1A NCOA6 EP300

1.67e-04130173int:PAX9
InteractionCITED2 interactions

CREBBP EP300

1.68e-0423172int:CITED2
InteractionHOXD10 interactions

CREBBP EP300

1.68e-0423172int:HOXD10
InteractionSMARCA2 interactions

ARID1A CREBBP EP300 KHSRP

1.70e-04346174int:SMARCA2
InteractionGCN1 interactions

NEK7 GTF2A1 TSC22D1 EP300

1.76e-04349174int:GCN1
InteractionTBX21 interactions

CREBBP EP300

1.83e-0424172int:TBX21
InteractionCNTN2 interactions

CREBBP EP300

1.83e-0424172int:CNTN2
InteractionNR6A1 interactions

CREBBP EP300

1.83e-0424172int:NR6A1
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

2.98e-051792486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

3.36e-05189291
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

ARID1A CREBBP EP300 KHSRP

4.77e-06180174M8239
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

TIA1 TSC22D1 ARPP21 SPATS2L

7.24e-06200174M9188
CoexpressionGSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN

NEK7 PHLDA1 GTF2A1 TSC22D1

7.24e-06200174M9628
CoexpressionBURTON_ADIPOGENESIS_1

PHLDA1 TSC22D1

1.82e-0431172M1612
CoexpressionBURTON_ADIPOGENESIS_1

PHLDA1 TSC22D1

1.82e-0431172MM1191
CoexpressionBURTON_ADIPOGENESIS_12

ARID1A GTF2A1

1.94e-0432172MM668
CoexpressionBURTON_ADIPOGENESIS_12

ARID1A GTF2A1

1.94e-0432172M1558
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

NEK7 ZNF462 CREBBP NCOA6

1.97e-04467174M1347
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

NEK7 ZNF462 CREBBP NCOA6

2.26e-04484174MM999
CoexpressionGSE3982_MEMORY_CD4_TCELL_VS_TH2_UP

NCOA6 R3HDM2 TSC22D1

2.59e-04196173M5381
CoexpressionGSE13306_TREG_VS_TCONV_UP

ZNF462 PHLDA1 TSC22D1

2.67e-04198173M3229
CoexpressionGSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

TIA1 TSC22D1 KHSRP

2.67e-04198173M9163
CoexpressionGSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP

NEK7 PRB1 CREBBP

2.71e-04199173M9420
CoexpressionGSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP

UBE2Q1 MED15 CREBBP

2.71e-04199173M3217
CoexpressionGSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP

MED15 PHLDA1 CREBBP

2.75e-04200173M9449
CoexpressionGSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP

TIA1 ARID1A TSC22D1

2.75e-04200173M5134
CoexpressionGSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN

R3HDM2 TSC22D1 SPATS2L

2.75e-04200173M4638
CoexpressionGSE27786_CD4_VS_CD8_TCELL_UP

ZNF462 CREBBP TSC22D1

2.75e-04200173M4819
CoexpressionGSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP

ARID1A NEK7 GTF2A1

2.75e-04200173M7981
CoexpressionGSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN

CREBBP NCOA6 ARPP21

2.75e-04200173M7532
CoexpressionFLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP

NEK7 CREBBP R3HDM2 TSC22D1

4.15e-04568174M4023
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Immature_CPNs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

ZNF462 PHLDA1 TSC22D1 ARPP21

8.28e-071981744e598aab92141e7d32ec963291ddeed14a21beba
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1A R3HDM2 SPATS2L

4.53e-05186173de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1A R3HDM2 SPATS2L

4.53e-051861730b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

CREBBP GTF2A1 EP300

4.53e-0518617303db813598b67b1e08f759758a1c2023396921fa
ToppCellMS-CD8-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

GTF2A1 KHSRP SPATS2L

4.83e-051901738c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PHLDA1 TSC22D1 ARPP21

5.13e-05194173920955e775617d6156c5ee8b90d2cecd01a70e12
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSC22D1 ARPP21 SPATS2L

5.21e-05195173787e95fb59c40bba784544b662fac37606ae1427
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PHLDA1 TSC22D1 ARPP21

5.29e-05196173fe2dd3a93fe22da93e24a400e154a68757985fc8
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PHLDA1 TSC22D1 ARPP21

5.37e-05197173d9a5b6171867de21d4ef12aa5a802fb4de9e0c00
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PHLDA1 PRB1 SPATS2L

5.37e-05197173d3539607d5477f5dfd85f1fa99b74677c0fa8937
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PHLDA1 PRB1 SPATS2L

5.37e-0519717340bd7c314ff5254d87737822078e7b9eaf23edf3
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF462 PHLDA1 TSC22D1

5.45e-051981733550798bfb9a426f3b28538a9778159bec2480d0
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 PHLDA1 SPATS2L

5.45e-051981738d7eb43b3e3b4a15265985143991e42afc20dc85
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

ZNF462 PHLDA1 TSC22D1

5.45e-0519817332d58379a89be19b6b1a494bf033416546771c19
ToppCell10x_3'_v2v3-Neoplastic-Stem-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF462 PHLDA1 TSC22D1

5.54e-0519917394baf00dad27964392c3fc34970a4e79d576d0d3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

ARID1A MED15 PHLDA1

5.62e-05200173d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-Neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TIA1 TSC22D1 ARPP21

5.62e-05200173b9538eb33ac86384e7e289a5a82fac4d56a7b9c2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Cortical_neuron|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ZNF462 TSC22D1 ARPP21

5.62e-052001737bba2ff09349c8db3d1ccf53520b12cbf7b0abac
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell|GW13 / Sample Type, Dataset, Time_group, and Cell type.

ARID1A MED15 PHLDA1

5.62e-052001733d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PHLDA1 SPATS2L

6.90e-04103172e28236a064a7c86e99e7e2edb1eb777f6034a9b4
ToppCell(05)_Ciliated-(0)_uninjured|(05)_Ciliated / shred by cell type and Timepoint

TSC22D1 SPATS2L

7.04e-041041720039ceeb70bec569b2d5e18be68f6c97973b80f5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

9.19e-041191726425425b2e622c97b6c74c530ccbfe394d3b202d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.03e-031261723539a8fdbb52d191f36dce68c38798ad4d2b491a
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA1 EP300

1.15e-03133172292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA1 EP300

1.15e-03133172f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Calb1_Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.16e-03134172b5466759285b4973850afb2e1be7c1d25f1c7927
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.18e-0313517254b2aaf8d322e01a3ff6099c2422d68ecccf96b4
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-Neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

PHLDA1 TSC22D1

1.20e-03136172b46450292e0cd549eb3bafdd3fed22f41d85bfbe
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ZNF462 PHLDA1

1.34e-0314417238ff324366ad5be626e3657c1e33277fc36ddd4c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.34e-031441720bbe670454846cf9bc7464ae4e91488415c4111d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Calb1_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.38e-0314617210839a4fce2e62955a90592f927a6e0c6a84bbad
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TSC22D1 ARPP21

1.42e-03148172a1269312903fc27830c1835dabf660c659a711be
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Akr1c18_Ntf3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.43e-031491721e77f03d2b32f366018fec3462d1b75f6e7febb9
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSC22D1 ARPP21

1.45e-03150172aa11579a57d671a55e64183d35c1340fda6dec14
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TSC22D1 SPATS2L

1.45e-03150172ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSC22D1 ARPP21

1.51e-0315317282b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

PHLDA1 TSC22D1

1.55e-0315517285eb60d285b8bfc095c341ae90c0e3b7e7dca9c1
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF462 R3HDM2

1.61e-031581726d2709b387945c015faa223c20d22b52a4082140
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.63e-03159172c64fff8d89f84d1f5a0cc432e31f56f741162505
ToppCellCOVID-19_Moderate-MAIT|COVID-19_Moderate / disease group, cell group and cell class

ZNF462 PHLDA1

1.63e-031591726d08d670c34eb6bb8ad5dad3293b3107c006236d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UBE2Q1 CREBBP

1.65e-031601728bb873704895c3b35bba8af78fedbabf7df42e71
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PHLDA1 SPATS2L

1.65e-0316017221f7c0337fbd99e4a20650920d8302d7318bd25e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

R3HDM2 ARPP21

1.71e-03163172431221a41d396b09170476179590eaf8a55266d8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.71e-03163172db6b7ce6f7221bb73c5e650ac51cdd5d7ef00675
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCOA6 ARPP21

1.71e-031631722d6fd2562d78be9f83fa35d811eb7e27eb8cc5d1
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

R3HDM2 ARPP21

1.71e-031631721e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.73e-03164172f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCellInt-URO-Myeloid-cDC1|Int-URO / Disease, Lineage and Cell Type

ZNF462 SPATS2L

1.73e-03164172f4628a7ff0dc765a5337ab499b3d61fc25573a16
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.75e-03165172d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.77e-0316617259d47c1fca7a8c70f6998f3367a9dbcb9b67966f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.77e-03166172b4241f8d2a0aa910dbb0d0d5d3631a9b73453fe9
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NEK7 PHLDA1

1.82e-031681722572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|390C / Donor, Lineage, Cell class and subclass (all cells)

PHLDA1 EP300

1.84e-03169172cfc9ff103d13a2d5eacc457e800f53fdd29f7738
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CREBBP TSC22D1

1.88e-03171172ea60d9e9df28ab991fbdb596784b44f6a9fc5827
ToppCellBac-SEP-Myeloid-cDC1|Bac-SEP / Disease, Lineage and Cell Type

ZNF462 SPATS2L

1.92e-03173172f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PHLDA1 SPATS2L

1.97e-031751726374ab186d7ccf7f6dfb858267edba8962789e15
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

R3HDM2 ARPP21

1.97e-0317517221f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

R3HDM2 ARPP21

1.97e-03175172ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 SPATS2L

1.99e-0317617288ca2f83d8301633232735f39b0683efe49d0b86
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 SPATS2L

1.99e-031761727292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHLDA1 TSC22D1

2.04e-03178172e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-MAIT|bone_marrow / Manually curated celltypes from each tissue

PHLDA1 SPATS2L

2.04e-031781727ac71e245864be2e8daecf555ff68235bd05827c
ToppCellfacs-Tongue-nan-24m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA1 TSC22D1

2.04e-03178172c92d7493853a717e2e7a76526e4e803564d182b7
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NEK7 SPATS2L

2.04e-031781728151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCellMild-Treg|Mild / Disease group and Cell class

PHLDA1 SPATS2L

2.04e-03178172e669fd95278e145f55126d0e6be8fb2d6184dbbd
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

PHLDA1 SPATS2L

2.08e-03180172adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell10x5'-bone_marrow-Myeloid_Mac-Macrophage|bone_marrow / Manually curated celltypes from each tissue

PHLDA1 TSC22D1

2.10e-03181172d2aa5b53162fb5c4cbbedbd2cb4b2b614e8c4afa
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TSC22D1 SPATS2L

2.10e-031811727e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

UBE2Q1 KHSRP

2.10e-03181172c029cecbd7182c70b9893d8c86f334c16291a0db
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF462 PHLDA1

2.13e-031821728a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF462 PHLDA1

2.13e-03182172831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF462 PHLDA1

2.13e-03182172e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF462 PHLDA1

2.13e-03182172a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TSC22D1 ARPP21

2.15e-031831728c8ce5a0d5535bef58ac10b7eb726f9c50af2ed8
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-Treg|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ZNF462 NCOA6

2.15e-031831725fb933acfe6bc555c90dba71e75d4be658763945
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MED15 SPATS2L

2.17e-03184172a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MED15 SPATS2L

2.17e-03184172081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

MED15 SPATS2L

2.17e-0318417245f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellSerous|World / shred by cell class for bronchial biopsy

PHLDA1 PRB1

2.17e-0318417209d0d1525c11dd326efd942684c03f79d992cf3b
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

R3HDM2 ARPP21

2.17e-031841726e17c8151d6dc543de16d804db956c63c3fda414
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PHLDA1 PRB1

2.17e-03184172f0cbb5b76e092be4188a9804ef5cf7a83cd7644f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NEK7 PHLDA1

2.17e-03184172c4c1a3d279ca733b865ce46570d7642dc137f9a4
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PHLDA1 PRB1

2.17e-031841725433ba7bbab553ff668619822d1a9208e15cd59f
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MED15 SPATS2L

2.17e-0318417284c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PHLDA1 TSC22D1

2.17e-0318417223c24ab5786af33d605bc445d06117b9da6c6331
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MED15 SPATS2L

2.17e-03184172d31d4116d1d196633784863781fa45673607a421
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF462 PHLDA1

2.20e-031851727aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PHLDA1 TSC22D1

2.20e-03185172b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF462 PHLDA1

2.20e-031851722e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

R3HDM2 SPATS2L

2.20e-031851721d874608aa2062024323512f68889219471b2f00
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 SPATS2L

2.22e-03186172f28d72b47624b69a580b4429e2be560a26898591
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 SPATS2L

2.22e-03186172b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

R3HDM2 ARPP21

2.22e-0318617256c139e679d640ea901ead657a8e8887e0fca098
ToppCellP15-Mesenchymal-developing_mesenchymal_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PHLDA1 TSC22D1

2.22e-03186172db9b67066fc003c7995ec205d15176bf40c97add
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PHLDA1 TSC22D1

2.22e-03186172b5c1afbe065746ed662527b2f052321f200ba0a8
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHLDA1 TSC22D1

2.24e-03187172ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHLDA1 TSC22D1

2.24e-03187172d591a3c216997663ab77710fed0d230ffc37e41a
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA1 CREBBP

2.24e-03187172663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 SPATS2L

2.24e-031871729d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHLDA1 TSC22D1

2.24e-03187172d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 CREBBP NCOA6 EP300

1.26e-071701751050_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 CREBBP NCOA6 EP300

1.33e-071721751072_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 CREBBP NCOA6 EP300

1.41e-071741751659_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 CREBBP NCOA6 EP300

1.45e-071751751058_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 CREBBP NCOA6 EP300

1.54e-071771751645_DN
Drug3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide

CREBBP EP300

5.24e-065172ctd:C575894
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 CREBBP EP300

7.09e-061731742881_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ARID1A CREBBP NCOA6 EP300

7.42e-061751741014_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ARID1A CREBBP GTF2A1 EP300

7.76e-061771743227_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

TIA1 ARID1A CREBBP EP300

7.76e-061771747047_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARID1A PHLDA1 GTF2A1 EP300

7.94e-061781744184_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 CREBBP NCOA6

7.94e-061781741112_DN
Drugfisetin; Down 200; 50uM; PC3; HG-U133A

ARID1A PHLDA1 NCOA6 TSC22D1

7.94e-06178174579_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

TIA1 ARID1A CREBBP EP300

8.30e-061801746886_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ARID1A MED15 CREBBP EP300

8.30e-061801744821_DN
Drugdimethylurea

PRB1 NCOA6

2.35e-0510172CID000007293
DrugAC1L2E0P

CREBBP GTF2A1 NCOA6 EP300

6.72e-05307174CID000019390
Drug4,4'-DBP

CREBBP EP300

8.91e-0519172CID000007034
Drug4-pyridoxic acid

PRB1 NCOA6

1.32e-0423172CID000006723
DrugSB 203580

PHLDA1 CREBBP TSC22D1 EP300

1.66e-04388174ctd:C093642
DrugAGN 194204

PHLDA1 CREBBP TSC22D1

2.23e-04162173ctd:C430898
Drugcalmidazolium chloride; Up 200; 5uM; MCF7; HG-U133A

PHLDA1 TSC22D1 EP300

2.36e-04165173486_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARID1A CREBBP EP300

2.57e-041701733746_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 EP300

2.62e-041711731000_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

ARID1A CREBBP EP300

2.62e-041711736879_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ARID1A CREBBP EP300

2.66e-041721732794_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ARID1A CREBBP EP300

2.71e-041731735987_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARID1A PHLDA1 EP300

2.71e-041731734237_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

ARID1A CREBBP EP300

2.71e-041731734458_DN
DrugHC toxin from Helminthosporium carbonum; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 EP300

2.76e-04174173909_DN
Drugtrichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 CREBBP

2.85e-04176173981_DN
Drugtrichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ARID1A PHLDA1 CREBBP

2.90e-04177173873_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

ARID1A CREBBP EP300

2.90e-041771736434_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARID1A CREBBP NCOA6

2.95e-041781737245_DN
DrugSAHA; Down 200; 10uM; PC3; HT_HG-U133A

ARID1A CREBBP EP300

2.95e-041781734444_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARID1A CREBBP EP300

3.00e-041791736609_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARID1A CREBBP EP300

3.00e-041791735822_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARID1A CREBBP EP300

3.05e-041801733688_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

ARID1A CREBBP EP300

3.05e-041801734541_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

ARID1A CREBBP EP300

3.10e-041811736951_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A

ARID1A CREBBP NCOA6

3.15e-041821731891_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A

ARID1A CREBBP NCOA6

3.15e-041821731951_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

TIA1 ARID1A CREBBP

3.20e-041831737136_DN
Drugglutamin

TIA1 ARID1A CREBBP EP300

3.20e-04461174CID000000738
DrugDoxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A

ARID1A TSC22D1 EP300

3.25e-041841735671_DN
DrugS x H

PRB1 NCOA6

3.26e-0436172CID009549209
DrugH-7 dihydrochloride; Down 200; 100uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 TSC22D1

3.51e-041891735936_DN
Drug0173570-0000 [211245-44-2]; Down 200; 10uM; PC3; HT_HG-U133A

PHLDA1 GTF2A1 KHSRP

3.51e-041891733690_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

ARID1A PHLDA1 NCOA6

3.62e-041911737503_DN
DrugTracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; HL60; HT_HG-U133A

MED15 PHLDA1 CREBBP

3.68e-041921732919_DN
DrugGalanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; PC3; HT_HG-U133A

MED15 PHLDA1 GTF2A1

3.74e-041931734186_DN
DrugZaprinast [37762-06-4]; Down 200; 14.8uM; PC3; HT_HG-U133A

ARID1A PHLDA1 KHSRP

3.74e-041931736749_DN
DrugGlipizide [29094-61-9]; Down 200; 9uM; PC3; HG-U133A

TIA1 NEK7 PHLDA1

3.74e-041931731926_DN
DrugTolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 GTF2A1

3.74e-041931733347_UP
DrugCetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 CREBBP

3.74e-041931732829_UP
DrugSkimmianine [83-95-4]; Up 200; 15.4uM; HL60; HT_HG-U133A

PHLDA1 CREBBP ARPP21

3.79e-041941732504_UP
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; HL60; HT_HG-U133A

TIA1 PHLDA1 TSC22D1

3.79e-041941731856_DN
DrugProglumide [6620-60-6]; Down 200; 12uM; MCF7; HT_HG-U133A

MED15 PHLDA1 CREBBP

3.79e-041941733861_DN
DrugRaloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A

ARID1A MED15 GTF2A1

3.85e-041951736235_UP
DrugKhellin [82-02-0]; Down 200; 15.4uM; PC3; HG-U133A

TIA1 PHLDA1 CREBBP

3.85e-041951731922_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; MCF7; HG-U133A

PHLDA1 CREBBP KHSRP

3.91e-04196173203_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

TIA1 MED15 GTF2A1

3.91e-041961736954_DN
DrugFluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; PC3; HT_HG-U133A

MED15 PHLDA1 KHSRP

3.91e-041961736757_DN
DrugFinasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 KHSRP

3.91e-041961734766_DN
DrugAmyleine hydrochloride [532-59-2]; Down 200; 14.8uM; PC3; HG-U133A

TIA1 NEK7 KHSRP

3.91e-041961731909_DN
DrugPentetic acid [67-43-6]; Down 200; 10.2uM; HL60; HT_HG-U133A

MED15 PHLDA1 GTF2A1

3.91e-041961733049_DN
DrugMexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A

MED15 PHLDA1 GTF2A1

3.97e-041971732324_DN
DrugScopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 CREBBP

3.97e-041971733357_UP
DrugIodixanol [92339-11-2]; Up 200; 2.6uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 GTF2A1

3.97e-041971733362_UP
DrugKetoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 KHSRP

3.97e-041971734751_DN
DrugPinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A

PHLDA1 CREBBP KHSRP

3.97e-041971735456_UP
DrugNaftopidil dihydrochloride [57149-08-3]; Down 200; 8.6uM; PC3; HT_HG-U133A

PHLDA1 GTF2A1 KHSRP

4.03e-041981734193_DN
DrugST021200; Down 200; 10uM; MCF7; HT_HG-U133A

PHLDA1 GTF2A1 KHSRP

4.03e-041981737554_DN
DrugProbenecid [57-66-9]; Down 200; 14uM; PC3; HT_HG-U133A

PHLDA1 GTF2A1 KHSRP

4.03e-041981734185_DN
DrugIsocarboxazid [59-63-2]; Up 200; 17.2uM; PC3; HT_HG-U133A

ARID1A PHLDA1 GTF2A1

4.03e-041981737383_UP
DrugProguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A

PHLDA1 GTF2A1 KHSRP

4.03e-041981733505_UP
Drug2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 EP300

4.09e-041991736982_DN
DrugCGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A

ARID1A PHLDA1 KHSRP

4.09e-041991736364_DN
DrugTheophylline monohydrate [5967-84-0]; Down 200; 20.2uM; PC3; HT_HG-U133A

PHLDA1 GTF2A1 KHSRP

4.09e-041991734228_DN
DrugPyrilamine maleate [59-33-6]; Up 200; 10uM; HL60; HG-U133A

TIA1 R3HDM2 KHSRP

4.09e-041991731568_UP
DrugYohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; HL60; HG-U133A

TIA1 TSC22D1 KHSRP

4.09e-041991731763_DN
DrugLY294002; Down 200; 10uM; MCF7; HG-U133A

PHLDA1 GTF2A1 EP300

4.09e-04199173258_DN
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

ARID1A CREBBP GTF2A1

4.15e-042001733354_UP
DrugPhentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A

MED15 PHLDA1 GTF2A1

4.15e-042001732323_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HG-U133A

TIA1 PHLDA1 TSC22D1

4.15e-042001731939_UP
DrugPromethazine hydrochloride [58-33-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A

PHLDA1 CREBBP KHSRP

4.15e-042001736477_UP
Drug1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine

CREBBP EP300

4.23e-0441172ctd:D019307
DrugN-methylmesoporphyrin

CREBBP EP300

4.44e-0442172CID000444708
DrugPhlorhizin

UBE2Q1 CREBBP EP300

6.63e-04235173ctd:D010695
DiseaseMenke-Hennekam syndrome

CREBBP EP300

3.12e-072172cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

3.12e-072172DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

3.12e-072172cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.12e-072172C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

3.12e-072172DOID:1933 (is_implicated_in)
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.12e-072172180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

3.12e-072172cv:C4551859
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

3.12e-072172C0035934
DiseaseCarcinoma, Transitional Cell

ARID1A CREBBP EP300

1.67e-0641173C0007138
DiseaseSmall cell carcinoma of lung

CREBBP EP300 KHSRP

3.87e-0654173C0149925
DiseaseAdenoid Cystic Carcinoma

ARID1A CREBBP EP300

2.48e-05100173C0010606
DiseaseT-Cell Lymphoma

ARID1A EP300

3.73e-0516172C0079772
DiseaseBladder Neoplasm

ARID1A CREBBP EP300

6.77e-05140173C0005695
DiseaseMalignant neoplasm of urinary bladder

ARID1A CREBBP EP300

6.92e-05141173C0005684
DiseaseParoxysmal atrial fibrillation

ZNF462 PHLDA1 SPATS2L

9.33e-05156173C0235480
DiseasePersistent atrial fibrillation

ZNF462 PHLDA1 SPATS2L

9.33e-05156173C2585653
Diseasefamilial atrial fibrillation

ZNF462 PHLDA1 SPATS2L

9.33e-05156173C3468561
DiseaseAtrial Fibrillation

ZNF462 PHLDA1 SPATS2L

1.01e-04160173C0004238
DiseaseSezary Syndrome

ARID1A CREBBP

1.09e-0427172C0036920
Diseasealcohol use disorder (implicated_via_orthology)

ARID1A CREBBP EP300

1.81e-04195173DOID:1574 (implicated_via_orthology)
Diseasecolon cancer (is_implicated_in)

ARID1A NCOA6

1.95e-0436172DOID:219 (is_implicated_in)
DiseaseBreast adenocarcinoma

ARID1A EP300

2.53e-0441172C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1A EP300

2.53e-0441172C0496956
DiseaseDiffuse Large B-Cell Lymphoma

CREBBP EP300

4.56e-0455172C0079744
DiseaseC-reactive protein measurement

UBE2Q1 NEK7 NCOA6 R3HDM2 ARPP21

4.64e-041206175EFO_0004458
Diseasepre-eclampsia (is_marker_for)

ARID1A CREBBP

5.07e-0458172DOID:10591 (is_marker_for)
DiseaseEndometrial Neoplasms

ARID1A EP300

5.07e-0458172C0014170
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

CREBBP EP300

5.60e-0461172C1961102
DiseaseEndometrial Carcinoma

ARID1A EP300

7.80e-0472172C0476089
Diseaserisk-taking behaviour

NEK7 EP300 ARPP21 SPATS2L

8.11e-04764174EFO_0008579
Diseaseneutrophil count

ARID1A UBE2Q1 NEK7 CREBBP GTF2A1

8.63e-041382175EFO_0004833
Diseaseirritability measurement

NCOA6 ARPP21

1.01e-0382172EFO_0009594
Diseasebeverage consumption measurement

ARPP21 SPATS2L

1.03e-0383172EFO_0010088
DiseaseSquamous cell carcinoma of esophagus

CREBBP EP300

1.35e-0395172C0279626
Diseaseurate measurement

ARID1A NCOA6 R3HDM2 SPATS2L

1.46e-03895174EFO_0004531
Diseasetriglyceride measurement, alcohol drinking

ARID1A R3HDM2

1.47e-0399172EFO_0004329, EFO_0004530
Diseasetriglyceride measurement, alcohol consumption measurement

ARID1A R3HDM2

1.53e-03101172EFO_0004530, EFO_0007878
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

ARID1A R3HDM2

1.71e-03107172EFO_0004614, EFO_0004615
Diseasecreatinine measurement, glomerular filtration rate

NCOA6 R3HDM2

2.04e-03117172EFO_0004518, EFO_0005208
DiseaseSquamous cell carcinoma

CREBBP EP300

2.29e-03124172C0007137
DiseaseIGF-1 measurement

ARID1A ZNF462 R3HDM2

2.57e-03488173EFO_0004627
DiseaseMalignant neoplasm of breast

ARID1A GTF2A1 NCOA6 EP300

2.84e-031074174C0006142
Diseasebreast cancer (is_implicated_in)

ARID1A NCOA6

3.32e-03150172DOID:1612 (is_implicated_in)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

TIA1 EP300

3.63e-03157172DOID:224 (biomarker_via_orthology)
Diseasealcohol consumption measurement, high density lipoprotein cholesterol measurement

ARID1A R3HDM2

3.86e-03162172EFO_0004612, EFO_0007878
Diseasealcohol drinking, high density lipoprotein cholesterol measurement

ARID1A R3HDM2

4.14e-03168172EFO_0004329, EFO_0004612
DiseaseLeukemia, Myelocytic, Acute

CREBBP EP300

4.39e-03173172C0023467
DiseaseFEV/FEC ratio

UBE2Q1 MED15 R3HDM2 SPATS2L

4.60e-031228174EFO_0004713
DiseaseAdenocarcinoma of lung (disorder)

CREBBP EP300

6.16e-03206172C0152013

Protein segments in the cluster

PeptideGeneStartEntry
NMGQQPAPQVQQPGL

EP300

301

Q09472
QQNQQPGQSPQGMRP

EP300

491

Q09472
PQQQPQQQLQPPMGG

EP300

2146

Q09472
MPPGQWQQAPLPQQQ

CREBBP

2016

Q92793
NQPGMQPQPGLQSQP

CREBBP

2111

Q92793
QPQPGLQSQPGMQPQ

CREBBP

2116

Q92793
QQQVQPPQPQMAGPL

ARPP21

531

Q9UBL0
QQVLPPQGYMQPPQQ

R3HDM2

501

Q9Y2K5
VVMQLNVPNGPQPPQ

R3HDM2

706

Q9Y2K5
GQGQPQQQQLPPAQP

ARID1A

1396

O14497
QGMQGPPVPQFQPQK

NEK7

6

Q8TDX7
QQALQAQPPIQQPPM

MED15

261

Q96RN5
QQMGPRPPQNNPLPQ

NCOA6

451

Q14686
PPNFMVMQQQPPNQG

NCOA6

486

Q14686
QGPPQQGGQQQQGPP

PRH1;

71

P02810
GGPQPPPTQQGQQQA

KHSRP

696

Q92945
LQPQPPQIQNGPMNG

SPATS2L

96

Q9NUQ6
APPPQQLQYGQQQPM

TSC22D1

621

Q15714
QQVIPQMQPGGVQAP

GTF2A1

186

P52655
KPQGPPQQEGNNPQG

PRB1

341

P04280
QQQQPGQGPAEPSQP

PHLDA1

201

Q8WV24
GVMLDPLQQQQPPQP

ZNF462

531

Q96JM2
QPPQGQNGSMLPNQP

TIA1

361

P31483
MQQPQPQGQQQPGPG

UBE2Q1

1

Q7Z7E8