FOXA1 FOXA2

OLIG3 FOXA1 FOXA2

FAM168B FAM168A

FAM168B FAM168A

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

SERPINB8 SERPINI1

SERPINB8 SERPINI1

SERPINB8 SERPINI1

SERPINB8 SERPINI1

SERPINB8 SERPINI1

SERPINB8 SERPINI1

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

FOXA1 FOXA2

Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer.

FOXA1 FOXA2

Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.

FOXA1 FOXA2

Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially.

FOXA1 FOXA2

The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation.

FOXA1 FOXA2

FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells.

FOXA1 FOXA2

Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice.

FOXA1 FOXA2

Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.

FOXA1 FOXA2

The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection.

FOXA1 FOXA2

Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.

FOXA1 FOXA2

Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells.

FOXA1 FOXA2

Differential induction of HNF-3 transcription factors during neuronal differentiation.

FOXA1 FOXA2

Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer.

FOXA1 FOXA2

Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer's Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks.

FOXA1 FOXA2

Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation.

FOXA1 FOXA2

Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells.

FOXA1 FOXA2

Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA.

FOXA1 FOXA2

Livebearing or egg-laying mammals: 27 decisive nucleotides of FAM168.

FAM168B FAM168A

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.

FOXA1 FOXA2

Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.

FOXA1 FOXA2

Foxa1 and Foxa2 regulate bile duct development in mice.

FOXA1 FOXA2

Foxa (HNF3) up-regulates vitronectin expression during retinoic acid-induced differentiation in mouse neuroblastoma Neuro2a cells.

FOXA1 FOXA2

Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation.

FOXA1 FOXA2

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

LIG3 FAM168B CLCN4 FOXA1

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth.

FOXA1 FOXA2

The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution.

FOXA1 FOXA2

Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.

FOXA1 FOXA2

Assignment of the human genes for hepatocyte nuclear factor 3-alpha, -beta, and -gamma (HNF3A, HNF3B, HNF3G) to 14q12-q13, 20p11, and 19q13.2-q13.4.

FOXA1 FOXA2

Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm.

FOXA1 FOXA2

Foxa1 and Foxa2 regulate bile duct development in mice.

FOXA1 FOXA2

Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression.

FOXA1 FOXA2

Mycoplasma pneumoniae modulates STAT3-STAT6/EGFR-FOXA2 signaling to induce overexpression of airway mucins.

FOXA2 STAT6

Molecular mechanisms of liver development and differentiation.

FOXA1 FOXA2

Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes.

FOXA1 FOXA2

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

FOXA1 FOXA2

The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis.

FOXA1 FOXA2

Forkhead box A1 (FOXA1) and A2 (FOXA2) oppositely regulate human type 1 iodothyronine deiodinase gene in liver.

FOXA1 FOXA2

Chromatin remodeling mediated by the FOXA1/A2 transcription factors activates CFTR expression in intestinal epithelial cells.

FOXA1 FOXA2

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.

FOXA1 FOXA2

FoxO1 and FoxA1/2 form a complex on DNA and cooperate to open chromatin at insulin-regulated genes.

FOXA1 FOXA2

FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity.

FOXA1 FOXA2

Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway.

FOXA1 FOXA2

The initiation of liver development is dependent on Foxa transcription factors.

FOXA1 FOXA2

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

FOXA1 FOXA2

The expression of p21 is upregulated by forkhead box A1/2 in p53-null H1299 cells.

FOXA1 FOXA2

Association between hepatocyte nuclear factor 6 (HNF-6) and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding.

FOXA1 FOXA2

Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2.

FOXA1 FOXA2

Collapse of the hepatic gene regulatory network in the absence of FoxA factors.

FOXA1 FOXA2

The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH.

FOXA1 FOXA2

ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer.

FOXA1 FOXA2

Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma.

FOXA1 FOXA2

Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes.

FOXA1 FOXA2

FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.

FOXA1 FOXA2

A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism.

FOXA1 FOXA2

Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues.

FOXA1 FOXA2

FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo.

FOXA1 FOXA2

Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh.

FOXA1 FOXA2

Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development.

FOXA1 FOXA2

Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.

FOXA1 FOXA2

Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M.

FOXA1 FOXA2

Expression of Foxa transcription factors in the developing and adult murine prostate.

FOXA1 FOXA2

The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression.

FOXA1 FOXA2

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.

FOXA1 FOXA2

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

LRP5 FOXA1 FOXA2

Foxa1 is essential for development and functional integrity of the subthalamic nucleus.

FOXA1 FOXA2

FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.

FOXA1 FOXA2

Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis.

FOXA1 FOXA2

Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter.

FOXA1 FOXA2

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

SMC4 LIG3 FLNC FOXA1 FOXA2 GLYR1 UBR4

The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives.

FOXA1 FOXA2

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo.

FOXA1 FOXA2

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins.

FOXA1 FOXA2

HNF-3 beta as a regulator of floor plate development.

FOXA1 FOXA2

Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord.

FOXA1 FOXA2

Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.

FOXA1 FOXA2

Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects.

FOXA1 FOXA2

Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals.

FOXA1 FOXA2

Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1.

FOXA1 FOXA2

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.

LRP5 FOXA1 FOXA2

Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes.

FOXA1 FOXA2

Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis.

FOXA1 FOXA2

Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.

FOXA1 FOXA2

Genetic patterning of the posterior neuropore region of curly tail mouse embryos: deficiency of Wnt5a expression.

FOXA1 FOXA2

The onecut transcription factor HNF6 is required for normal development of the biliary tract.

FOXA1 FOXA2

Genetic patterning of the developing mouse tail at the time of posterior neuropore closure.

FOXA1 FOXA2

Maintenance of the specification of the anterior definitive endoderm and forebrain depends on the axial mesendoderm: a study using HNF3beta/Foxa2 conditional mutants.

FOXA1 FOXA2

Revising the embryonic origin of thyroid C cells in mice and humans.

FOXA1 FOXA2

Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function.

FOXA1 FOXA2

The eed mutation disrupts anterior mesoderm production in mice.

FOXA1 FOXA2

Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3 alpha, HNF-3 beta, HNF-3 gamma, and HNF-4.

FOXA1 FOXA2

Foxa1 and Foxa2 are required for formation of the intervertebral discs.

FOXA1 FOXA2

Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.

FOXA2 STAT6

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.

RIT1 UBR4

Neurogenin3 cooperates with Foxa2 to autoactivate its own expression.

FOXA1 FOXA2

Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity.

FOXA1 FOXA2

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.

FOXA1 FOXA2

Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte.

FOXA1 FOXA2

Genome-wide chromatin accessibility and transcriptome profiling show minimal epigenome changes and coordinated transcriptional dysregulation of hedgehog signaling in Danforth's short tail mice.

FOXA1 FOXA2

Requirement for Shh and Fox family genes at different stages in sweat gland development.

FOXA1 FOXA2

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SMC4 LIG3 CLINT1 GTPBP1 PC VPS13C GLYR1 UBR4

Identification of proximal SUMO-dependent interactors using SUMO-ID.

LIG3 FLNC CHD8 CLINT1 PC

RIT1 LIG3 FLNC SERPINB8 SERPINI1 UBR4

SMC4 SERPINI1

LRP5 FAM168A

LRP5 FAM168A PC

SERPINB8 SERPINI1

FOXA1 FOXA2

FOXA1 FOXA2 PC CARMIL1

FOXA1 FOXA2 PC CARMIL1

LRP5 FLNC

HMGCR RBP3

FLNC HMGCR

CHD8

2426

GTPBP1

276

CLCN4

1

FAM168A

196

CLINT1

581

HMGCR

651

LRP5

1451

LRP5

1456

CES4A

221

FLNC

2661

GLYR1

186

GXYLT1

266

LIG3

701

OLIG3

41

FOXA1

36

CCDC73

741

CARMIL1

576

FAM186A

531

SLC22A6

456

FAM168B

146

SERPINI1

56

FOXA2

26

FOXA2

46

PLIN4

381

RTL9

556

RTL9

561

RTL9

816

RTL9

941

OSBPL10

561

SERPINB8

41

RBP3

891

RIT1

26

SLC23A2

1

STAT6

671

SMC4

751

VPS13C

1976

ZKSCAN7

266

UBR4

4796

PC

801

TASP1

1

TMEM98

111