Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	TRERF1 DRD3 HIVEP2 MED14 AKNA ETV5 POU1F1 RELA SKI SIRT1 TFDP1 TFE3 KMT2C HOXB3 TAF3 NFATC4 SPZ1 BRD4 CD40 AATF PAX7 FUBP3 NOTCH1 SMAD4 SMAD5 ZNF574 NOBOX	2.87e-07	1390	135	27	GO:0045944
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	SEMA6C ARHGAP32 AKAP5 ATP7A NUMBL FAT3 PLEKHM1 SIRT1 TBC1D17 SCARF1 PTPN9 NEO1 TRIM67 FIG4 NFATC4 TBC1D1 CDC20	3.87e-05	846	135	17	GO:0120035
GeneOntologyBiologicalProcess	pattern specification process	SHROOM3 IFT172 SKI HOXB3 DCANP1 POFUT1 PAX7 EMX2 NOTCH1 SMAD4 SMAD5 CCDC40 DNAH11	4.28e-05	526	135	13	GO:0007389
GeneOntologyBiologicalProcess	regulation of cell projection organization	SEMA6C ARHGAP32 AKAP5 ATP7A NUMBL FAT3 PLEKHM1 SIRT1 TBC1D17 SCARF1 PTPN9 NEO1 TRIM67 FIG4 NFATC4 TBC1D1 CDC20	4.96e-05	863	135	17	GO:0031344
GeneOntologyCellularComponent	transcription regulator complex	TRERF1 HIVEP2 MED14 POU1F1 RELA CHD4 SKI BATF2 TFDP1 TFE3 TAF3 GTF3C2 NFATC4 AATF MMS19 PAX7 SMAD4 SMAD5 NOBOX	1.63e-08	596	139	19	GO:0005667
Domain	VCX_VCY	VCX2 VCX3A VCX3B VCX	1.22e-08	5	133	4	PF15231
Domain	VCX/VCY1	VCX2 VCX3A VCX3B VCX	1.22e-08	5	133	4	IPR026653
Domain	DUF4599	SPATA31E1 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31D1	1.29e-08	12	133	5	PF15371
Domain	DUF4599	SPATA31E1 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31D1	1.29e-08	12	133	5	IPR027970
Domain	Shroom_fam	SHROOM3 SHROOM4	2.99e-04	4	133	2	IPR027685
Domain	ASD2_dom	SHROOM3 SHROOM4	2.99e-04	4	133	2	IPR014799
Domain	ASD2	SHROOM3 SHROOM4	2.99e-04	4	133	2	PF08687
Domain	ASD2	SHROOM3 SHROOM4	2.99e-04	4	133	2	PS51307
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C SHROOM3 HIVEP2 MAN2B1 SH2B3 MED14 AKNA MED13L NPHP4 AHDC1 PLEKHM1 TBC1D17 TFE3 RHPN1 KMT2C FAT1 TRAPPC12 RALGPS1 BRD4 PXN POFUT1 NOTCH1 CYB5R2	9.27e-11	1105	139	23	35748872
Pubmed	A member of a gene family on Xp22.3, VCX-A, is deleted in patients with X-linked nonspecific mental retardation.	VCX2 VCX3A VCX3B VCX	2.44e-10	4	139	4	10903929
Pubmed	A census of human transcription factors: function, expression and evolution.	TRERF1 TSHZ3 HIVEP2 AKNA POU1F1 RELA SKI BATF2 SOX13 ZBTB24 TFDP1 TFE3 HOXB3 NFATC4 PROX2 PAX7 EMX2 SMAD4 SMAD5 NOBOX	6.71e-10	908	139	20	19274049
Pubmed	A human sex-chromosomal gene family expressed in male germ cells and encoding variably charged proteins.	VCX2 VCX3A VCY VCX	1.22e-09	5	139	4	10607842
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	3.64e-09	6	139	4	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	3.64e-09	6	139	4	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1 HERPUD2	3.79e-08	24	139	5	32212159
Pubmed	Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin.	MED14 KMT2C TAF3 GTF3C2 SMAD4 SMAD5	3.91e-08	48	139	6	27703004
Pubmed	Human transcription factor protein interaction networks.	TRERF1 ARHGAP32 TSHZ3 ETV5 RELA SKI SOX13 SIRT1 TFDP1 TFE3 DAP3 KMT2C FAT1 TAF3 GTF3C2 NFATC4 SPZ1 OTUD4 N4BP1 PAX7 FUBP3 SMAD5	5.86e-08	1429	139	22	35140242
Pubmed	Analysis of the VCX3A, VCX2 and VCX3B genes shows that VCX3A gene deletion is not sufficient to result in mental retardation in X-linked ichthyosis.	VCX2 VCX3A VCX3B	6.25e-08	3	139	3	18076704
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HIVEP2 TRIM25 PAPOLB RELA CHD4 SKI ZBTB24 SIRT1 TFDP1 NFATC4 SPZ1 AATF MMS19 EMX2 FUBP3 SMAD4 SMAD5	8.94e-08	877	139	17	20211142
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 TSHZ3 HIVEP2 MSH3 SKI SOX13 AHDC1 SIRT1 TFDP1 KMT2C TAF3	1.87e-07	351	139	11	38297188
Pubmed	Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells.	SKI SMAD4 SMAD5	6.21e-07	5	139	3	11121043
Pubmed	A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family.	VCX3B VCY VCX	1.24e-06	6	139	3	17342728
Pubmed	Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski.	SKI SMAD4 SMAD5	2.16e-06	7	139	3	14699069
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HIVEP2 ETV5 CHD4 SOX13 TFDP1 TFE3 KMT2C NFATC4 BRD4 PROX2 PXN PAX7 EMX2	5.84e-06	709	139	13	22988430
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TSHZ3 BAZ2B ARHGEF5 CHD4 MSH3 ZBTB24 SIRT1 TFDP1 DAP3 TAF3 GTF3C2 BRD4	6.50e-06	608	139	12	36089195
Pubmed	A genome-wide association study identifies three new risk loci for Kawasaki disease.	NUMBL BLK CD40	7.34e-06	10	139	3	22446962
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	TRERF1 ARHGAP32 TSHZ3 SHROOM3 TRIM25 SPATA31E1 ARHGEF5 NFATC4 PAX7 NOTCH1	9.71e-06	430	139	10	35044719
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARHGAP32 WDR64 IDE TFE3 DAP3 PTPN9 PIGT TRAPPC12 OTUD4 AATF FER1L5 DNAH11	1.05e-05	638	139	12	31182584
Pubmed	SIRT1 overexpression decreases cisplatin-induced acetylation of NF-κB p65 subunit and cytotoxicity in renal proximal tubule cells.	RELA SIRT1	1.59e-05	2	139	2	22330808
Pubmed	Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling.	POFUT1 NOTCH1	1.59e-05	2	139	2	25107841
Pubmed	Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration.	PAX7 SMAD4	1.59e-05	2	139	2	27855784
Pubmed	Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancer.	SIRT1 NOTCH1	1.59e-05	2	139	2	25420528
Pubmed	Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.	RELA SIRT1	1.59e-05	2	139	2	17041012
Pubmed	Modulation of neuritogenesis by a protein implicated in X-linked mental retardation.	VCX3A VCX3B	1.59e-05	2	139	2	19812318
Pubmed	Endothelial dysfunction is a superinducer of syndecan-4: fibrogenic role of its ectodomain.	SIRT1 SDC4	1.59e-05	2	139	2	29101181
Pubmed	The Brd4 acetyllysine-binding protein is involved in activation of polyomavirus JC.	RELA BRD4	1.59e-05	2	139	2	27007123
Pubmed	Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations.	POFUT1 NOTCH1	1.59e-05	2	139	2	28334865
Pubmed	SIRT1 longevity factor suppresses NF-kappaB -driven immune responses: regulation of aging via NF-kappaB acetylation?	RELA SIRT1	1.59e-05	2	139	2	18800364
Pubmed	A heterocyclic molecule kartogenin induces collagen synthesis of human dermal fibroblasts by activating the smad4/smad5 pathway.	SMAD4 SMAD5	1.59e-05	2	139	2	24928394
Pubmed	miRNA-302e attenuates inflammation in infantile pneumonia though the RelA/BRD4/NF-κB signaling pathway.	RELA BRD4	1.59e-05	2	139	2	31115487
Pubmed	Regulation of CD40 and CD40 ligand by the AT-hook transcription factor AKNA.	AKNA CD40	1.59e-05	2	139	2	11268217
Pubmed	Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation.	ALS2 SHROOM4	1.59e-05	2	139	2	16249884
Pubmed	NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma.	RELA FAT1	1.59e-05	2	139	2	31992226
Pubmed	Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA.	RELA BRD4	1.59e-05	2	139	2	23686307
Pubmed	Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.	RELA SIRT1	1.59e-05	2	139	2	15152190
Pubmed	Synergistic association of Notch and NFκB signaling and role of Notch signaling in modulating epithelial to mesenchymal transition in colorectal adenocarcinoma.	RELA NOTCH1	1.59e-05	2	139	2	25257945
Pubmed	Melatonin reverses H2 O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB.	RELA SIRT1	1.59e-05	2	139	2	28295567
Pubmed	Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer.	RELA NOTCH1	1.59e-05	2	139	2	21771876
Pubmed	Expression and localization of VCX/Y proteins and their possible involvement in regulation of ribosome assembly during spermatogenesis.	VCX3B VCX	1.59e-05	2	139	2	12862317
Pubmed	Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).	RELA SIRT1	1.59e-05	2	139	2	35166167
Pubmed	Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappaB signaling pathway in vitro.	RELA NOTCH1	1.59e-05	2	139	2	20346213
Pubmed	SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-κB pathway.	RELA SIRT1	1.59e-05	2	139	2	29784872
Pubmed	Amplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice.	CD22 CD40	1.59e-05	2	139	2	21799861
Pubmed	FOXO3 Activation Prevents Cellular Senescence in Emphysema Induced by Cigarette Smoke.	SIRT1 PAX7	1.59e-05	2	139	2	36656684
Pubmed	CD40-Mediated NF-κB Activation in B Cells Is Increased in Multiple Sclerosis and Modulated by Therapeutics.	RELA CD40	1.59e-05	2	139	2	27798157
Pubmed	Roles of Pofut1 and O-fucose in mammalian Notch signaling.	POFUT1 NOTCH1	1.59e-05	2	139	2	18347015
Pubmed	Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.	RELA SIRT1	1.59e-05	2	139	2	37200907
Pubmed	Expression patterns of RelA and c-mip are associated with different glomerular diseases following anti-VEGF therapy.	RELA CMIP	1.59e-05	2	139	2	24067439
Pubmed	Involvement of the p65/RelA subunit of NF-kappaB in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells.	RELA SIRT1	1.59e-05	2	139	2	20617556
Pubmed	Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress.	NFATC4 SDC4	1.59e-05	2	139	2	23178899
Pubmed	Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity.	RELA SIRT1	1.59e-05	2	139	2	28600541
Pubmed	Notch-1 promotes the malignant progression of osteosarcoma through the activation of cell division cycle 20.	CDC20 NOTCH1	1.59e-05	2	139	2	33411691
Pubmed	NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis.	RELA BRD4	1.59e-05	2	139	2	25263595
Pubmed	SIRT1 regulates TNF-α-induced expression of CD40 in 3T3-L1 adipocytes via NF-κB pathway.	SIRT1 CD40	1.59e-05	2	139	2	22717288
Pubmed	A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets.	VCY VCX	1.59e-05	2	139	2	24970476
Pubmed	Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.	RELA BRD4	1.59e-05	2	139	2	22645123
Pubmed	Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development.	POFUT1 NOTCH1	1.59e-05	2	139	2	38976017
Pubmed	The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells.	SIRT1 PAX7	1.59e-05	2	139	2	25600643
Pubmed	MiR-34a is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation through the SIRT1/NFκB pathway.	RELA SIRT1	1.59e-05	2	139	2	23103739
Pubmed	Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signaling.	TFE3 SMAD4	1.59e-05	2	139	2	10636910
Pubmed	Overexpression of Pofut1 and activated Notch1 may be associated with poor prognosis in breast cancer.	POFUT1 NOTCH1	1.59e-05	2	139	2	28709865
Pubmed	Endothelial sirtuin 1 inactivation enhances capillary rarefaction and fibrosis following kidney injury through Notch activation.	SIRT1 NOTCH1	1.59e-05	2	139	2	27524235
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	NUMBL RELA SOX13 ARAF SYDE1 TBC1D17 TFE3 C5orf34 DBF4 PXN OTUD4 AATF CDC20 SMAD4 SMAD5	1.87e-05	1038	139	15	26673895
Pubmed	Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart.	NUMBL NOTCH1 SMAD5	2.20e-05	14	139	3	22865640
Pubmed	Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture.	PAX7 SMAD4 SMAD5	2.20e-05	14	139	3	33248111
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	DENND5B RNPC3 SYDE1 TFDP1 DAP3 KMT2C FAT1 TRAPPC12 TBC1D1 MMS19 SMAD4 DNAH11	2.24e-05	689	139	12	36543142
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TRERF1 ETV5 RELA SOX13 ZBTB24 TFDP1 TFE3 DBF4 BRD4 PXN AATF SMAD4 NOBOX	2.31e-05	808	139	13	20412781
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARHGAP32 BAZ2B RNPC3 NPHP4 SHROOM4 CMIP FIG4 N4BP1 REXO1L1P PALLD	3.12e-05	493	139	10	15368895
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	AKNA ETV5 KIRREL2 PLEKHM1 DAP3 KMT2C DNAH11	4.46e-05	233	139	7	37704626
Pubmed	Direct interaction of Ski with either Smad3 or Smad4 is necessary and sufficient for Ski-mediated repression of transforming growth factor-beta signaling.	SKI SMAD4	4.75e-05	3	139	2	12857746
Pubmed	Pofut1 point-mutations that disrupt O-fucosyltransferase activity destabilize the protein and abolish Notch1 signaling during mouse somitogenesis.	POFUT1 NOTCH1	4.75e-05	3	139	2	29095923
Pubmed	Notch1 and Notch2 Coordinately Regulate Stem Cell Function in the Quiescent and Activated States of Muscle Satellite Cells.	PAX7 NOTCH1	4.75e-05	3	139	2	29139178
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT3 FAT1	4.75e-05	3	139	2	15744052
Pubmed	Syndecan-3 and Notch cooperate in regulating adult myogenesis.	PAX7 NOTCH1	4.75e-05	3	139	2	20696709
Pubmed	Caveolin-1 mediates chemoresistance in cisplatin-resistant ovarian cancer cells by targeting apoptosis through the Notch-1/Akt/NF-κB pathway.	RELA NOTCH1	4.75e-05	3	139	2	26503358
Pubmed	Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.	SKI SMAD4	4.75e-05	3	139	2	26977879
Pubmed	NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.	SIRT1 PAX7	4.75e-05	3	139	2	27127236
Pubmed	NF-κB signaling activation via increases in BRD2 and BRD4 confers resistance to the bromodomain inhibitor I-BET151 in U937 cells.	RELA BRD4	4.75e-05	3	139	2	30300821
Pubmed	Cell surface proteoglycans syndecan-1 and -4 bind overlapping but distinct sites in laminin α3 LG45 protein domain.	LAMA3 SDC4	4.75e-05	3	139	2	22351752
Pubmed	The Notch regulator Numb links the Notch and TCR signaling pathways.	NUMBL NOTCH1	4.75e-05	3	139	2	15634911
Pubmed	Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility.	FER1L4 FER1L5	4.75e-05	3	139	2	36696506
Pubmed	Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins.	TFE3 SMAD4	4.75e-05	3	139	2	10557285
Pubmed	Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB.	RELA BRD4	4.75e-05	3	139	2	29463681
Pubmed	BRD4 Couples NF-κB/RelA with Airway Inflammation and the IRF-RIG-I Amplification Loop in Respiratory Syncytial Virus Infection.	RELA BRD4	4.75e-05	3	139	2	28077651
Pubmed	Overexpression of the BMP4/SMAD signaling pathway in skull base chordomas is associated with poor prognosis.	SMAD4 SMAD5	4.75e-05	3	139	2	26339396
Pubmed	T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells.	RELA NOTCH1	4.75e-05	3	139	2	8642313
Pubmed	Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.	POFUT1 NOTCH1	4.75e-05	3	139	2	16885355
Pubmed	PPARα agonist fenofibrate attenuates TNF-α-induced CD40 expression in 3T3-L1 adipocytes via the SIRT1-dependent signaling pathway.	SIRT1 CD40	4.75e-05	3	139	2	23603572
Pubmed	Production of proinflammatory mediators in activated microglia is synergistically regulated by Notch-1, glycogen synthase kinase (GSK-3β) and NF-κB/p65 signalling.	RELA NOTCH1	4.75e-05	3	139	2	29049420
Pubmed	C-mip interacts physically with RelA and inhibits nuclear factor kappa B activity.	RELA CMIP	4.75e-05	3	139	2	19019440
Pubmed	Are Ski and SnoN Involved in the Tumorigenesis of Oral Squamous Cell Carcinoma Through Smad4?	SKI SMAD4	4.75e-05	3	139	2	29734252
Pubmed	A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation.	PPP2R5C PXN	4.75e-05	3	139	2	10675325
Pubmed	A peptide that blocks the interaction of NF-κB p65 subunit with Smad4 enhances BMP2-induced osteogenesis.	RELA SMAD4	4.75e-05	3	139	2	29663368
Pubmed	B cell antigen receptor and CD40 differentially regulate CD22 tyrosine phosphorylation.	CD22 CD40	4.75e-05	3	139	2	16393971
Pubmed	Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.	RELA NOTCH1	4.75e-05	3	139	2	32991757
Pubmed	Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice.	CIPC PAX7	4.75e-05	3	139	2	35705041
Pubmed	Molecular mechanisms of syndecan-4 upregulation by TNF-α in the endothelium-like EAhy926 cells.	RELA SDC4	4.75e-05	3	139	2	23576453
Pubmed	SIRT1 inhibits TGF-β-induced endothelial-mesenchymal transition in human endothelial cells with Smad4 deacetylation.	SIRT1 SMAD4	4.75e-05	3	139	2	29856490
Interaction	TOP3B interactions	SEMA6C SHROOM3 HIVEP2 TRIM25 MAN2B1 SH2B3 MED14 AKNA IREB2 MSH3 MED13L NPHP4 AHDC1 PLEKHM1 TBC1D17 TFE3 RHPN1 KMT2C FAT1 TRAPPC12 RALGPS1 BRD4 PXN OTUD4 MMS19 POFUT1 FUBP3 NOTCH1 CYB5R2	1.11e-07	1470	135	29	int:TOP3B
Interaction	DCANP1 interactions	FAT3 IDE DCANP1 FAT1	6.90e-06	19	135	4	int:DCANP1
Interaction	AR interactions	TRERF1 TRIM25 MED14 ETV5 RELA CHD4 IDE MED13L SKI AHDC1 SIRT1 BLK DAP3 KMT2C BRD4 PXN AATF MMS19 FUBP3 SMAD4	1.00e-05	992	135	20	int:AR
Interaction	ZMIZ1 interactions	TRIM25 SIRT1 TRIM67 NOTCH1 SMAD4	1.10e-05	44	135	5	int:ZMIZ1
Interaction	SMAD2 interactions	RNPC3 IRAK2 RELA SKI KMT2C TAF3 TRIM67 GTF3C2 TBC1D1 HSD17B3 SMAD4 SMAD5	1.12e-05	385	135	12	int:SMAD2
Interaction	DNASE2 interactions	TRIM25 MAN2B1 DNASE2B TRIM67	2.57e-05	26	135	4	int:DNASE2
Interaction	KAT2A interactions	RELA BATF2 SIRT1 TFE3 TAF3 BRD4 NOTCH1 SMAD5	2.93e-05	180	135	8	int:KAT2A
GeneFamily	Variable charge X/Y family	VCX2 VCX3A VCX3B VCY VCX	2.94e-11	6	101	5	368
GeneFamily	Ferlin family	FER1L4 FER1L5	4.57e-04	6	101	2	828
GeneFamily	SMAD family	SMAD4 SMAD5	8.46e-04	8	101	2	750
GeneFamily	PHD finger proteins	BAZ2B CHD4 KMT2C TAF3	1.62e-03	90	101	4	88
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	HIVEP2 SH2B3 BAZ2B MED13L AHDC1 ZBTB24 FAT1 OTUD4 N4BP1 SMAD5	4.52e-06	300	138	10	M8702
Coexpression	GSE14413_UNSTIM_VS_IFNB_STIM_NIH3T3_CELLS_UP	TRERF1 CHD4 SCARF1 PIGT TAF3 SPZ1 PXN	1.01e-05	141	138	7	M466
Coexpression	GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP	TRERF1 TRIM25 BAZ2B APLP2 MED13L F5 PPP2R5C TBC1D1	1.06e-05	198	138	8	M7948
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHROOM3 ADGRG3 FAT3 F5 TRIM67 HMCN1 COL14A1	2.72e-06	195	139	7	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHROOM3 ADGRG3 FAT3 F5 TRIM67 HMCN1 COL14A1	2.72e-06	195	139	7	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TRERF1 TSHZ3 FAT3 ETV5 HOXB3 NEO1 DYNC1I1	2.72e-06	195	139	7	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRIM25 FAT3 HOXB3 HMCN1 FIG4 COL14A1 PALLD	2.90e-06	197	139	7	d7cef7881abd807a679432766ced609a6efd1067
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRIM25 FAT3 HOXB3 HMCN1 FIG4 COL14A1 PALLD	2.90e-06	197	139	7	20a5958512bdb99daeb8f4d244df53e4f048f879
ToppCell	droplet-Thymus-nan-18m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA DENND5B IRAK2 BLK CD22 SDC4	1.00e-05	157	139	6	a9e077f686382303f0437ebfa4f11d273ba9fe40
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|Monocyte / Lineage, cell class and subclass	ADGRG3 IRAK2 APLP2 F5 PXN SDC4	1.53e-05	169	139	6	7c3144a6599787f28662f5b22b8e45f4a115aeda
ToppCell	Children_(3_yrs)-Immune-B_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DENND5B IRAK2 BLK TRIM67 CD22 PARP15	1.58e-05	170	139	6	e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA DENND5B BLK CD22 SDC4 DYNC1I1	1.69e-05	172	139	6	356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA DENND5B BLK CD22 SDC4 DYNC1I1	1.69e-05	172	139	6	46fadeee483fdf8402df92ec98575a09c6c15b16
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA DENND5B BLK CD22 SDC4 DYNC1I1	1.69e-05	172	139	6	438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRIM25 MAP3K7CL SOX13 AHDC1 BLK RALGPS1	1.86e-05	175	139	6	87e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HIVEP2 SHROOM4 HMCN1 POFUT1 FUBP3 SDC4	2.05e-05	178	139	6	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	TRIM25 BAZ2B BATF2 KMT2C N4BP1 XAF1	2.39e-05	183	139	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND5B SIRT1 BLK CD22 CD40 PARP15	2.54e-05	185	139	6	e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA TRIM25 BAZ2B BLK CD22 SDC4	2.70e-05	187	139	6	b51af2824e65734f333b1325117f4a2e88b17c23
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TSHZ3 HOXB3 NEO1 CD40 COL14A1 PALLD	2.78e-05	188	139	6	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	3'_v3-Lung-Myeloid_Dendritic-Cycling_Dendritic\|Lung / Manually curated celltypes from each tissue	ETV5 SCARF1 DCANP1 NFATC4 CDC20 PALLD	2.78e-05	188	139	6	0e8ac42c439f30a05e015210e1d5c2dcb9d9d471
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHROOM4 CD22 NFATC4 EMX2 SDC4 NOTCH1	2.95e-05	190	139	6	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	DENND5B IRAK2 BLK CD22 CD40 PARP15	2.95e-05	190	139	6	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Mixed_Serous_and_Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	VCX2 VCX3A POU1F1 PAX7 VCX	3.06e-05	115	139	5	c724e8b1fddcefdaa8d247aaff68c986538068f7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DENND5B KIRREL2 BLK CD22 CD40 PARP15	3.22e-05	193	139	6	bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	SH2B3 CHD4 CD22 PROX2 CD40 PARP15	3.22e-05	193	139	6	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	IPF-Lymphoid-T_Cytotoxic\|Lymphoid / Disease state, Lineage and Cell class	TRERF1 AKNA CMIP PPP2R5C N4BP1 HERPUD2	3.22e-05	193	139	6	3c8a022dbd4f8d25b14fd137ce64c2713a7dbe41
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TRERF1 TSHZ3 FAT3 ETV5 HOXB3 DYNC1I1	3.32e-05	194	139	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGAP32 RNPC3 LAMA3 ETV5 FAT1 SDC4	3.62e-05	197	139	6	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	mild-B_memory\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DENND5B BLK FAT1 CD22 CD40 PARP15	3.83e-05	199	139	6	e6ac9a0959b0de2c6a99298feb7715aa80ade1dd
ToppCell	severe-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DENND5B ZBTB24 BLK CD22 CD40 PARP15	3.83e-05	199	139	6	17283d75a2a900369f63ed02996e7ede97f46140
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TSHZ3 SKI HOXB3 CMIP TRIM67 MTUS2	3.93e-05	200	139	6	a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 BLK CD22 POFUT1 NOTCH1	4.56e-05	125	139	5	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DENND5B BLK SHROOM4 CD22 PARP15	1.02e-04	148	139	5	6ffa212f0cc44c40d2143816dc6cfd82fbf09a33
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_Inf._Macrophages\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAP3K7CL F5 CD40 SDC4 CYB5R2	1.12e-04	151	139	5	88f7498f29e43441e0982f9f97ea563edf2835a4
ToppCell	VE-Treg-naive_CD4\|VE / Condition, Cell_class and T cell subcluster	RNPC3 F5 SHROOM4 HMCN1 SDC4	1.30e-04	156	139	5	6501baf73616e702946de9fb13d267e30a68888b
ToppCell	lymphoid-T_cell-pro-T_cell\|T_cell / Lineage, cell class and subclass	DENND5B VCX3B CD40 EMX2 SDC4	1.46e-04	160	139	5	66fe86d2f37983761141e5bb3de127f0b4bb0951
ToppCell	metastatic_Brain-B_lymphocytes-Undetermined\|metastatic_Brain / Location, Cell class and cell subclass	ZBTB24 BLK CD22 CD40 PARP15	1.60e-04	163	139	5	4eac7fd8acdb7f09ce739335f22a879f9b8febfb
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP7A ETV5 PAPOLB PLEKHM1 PLA2G4F	1.60e-04	163	139	5	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP7A ETV5 PAPOLB PLEKHM1 PLA2G4F	1.60e-04	163	139	5	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-immature_B_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ZBTB24 BLK CD22 CD40 PARP15	1.64e-04	164	139	5	69b6566fb88c7449b7ab9056b57508cb6a1aa2af
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYDE1 NFATC4 DBF4 CDC20 PALLD	1.69e-04	165	139	5	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYDE1 NFATC4 DBF4 CDC20 PALLD	1.69e-04	165	139	5	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	mild_COVID-19_(asymptomatic)-B_intermediate\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	DENND5B BLK CD22 CD40 CYB5R2	1.74e-04	166	139	5	8de8f388f24436b84e19ef460476fdbda4d16abf
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells\|GI_small-bowel / Manually curated celltypes from each tissue	DENND5B BLK CD22 CD40 DNAH11	1.84e-04	168	139	5	8e025bb0541746e232b77ac0e31412ae71420c47
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B\|GI_small-bowel / Manually curated celltypes from each tissue	DENND5B BLK CD22 CD40 DNAH11	1.84e-04	168	139	5	5535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL10RA ADGRG3 FAT3 PANK1 CIPC	1.94e-04	170	139	5	4b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DENND5B BLK CD22 CD40 PARP15	1.99e-04	171	139	5	b6ee3a6bc436df5e9129b8e0bed9fa3078a4ff23
ToppCell	Influenza_Severe-B_intermediate\|World / Disease group and Cell class	DENND5B BLK CD22 CD40 MTUS2	1.99e-04	171	139	5	4d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP5 BLK CD22 CD40 PARP15	2.05e-04	172	139	5	172e3c78f8e97988a4fd8624514e731282ddc16d
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP5 BLK CD22 CD40 PARP15	2.05e-04	172	139	5	5fb0ea6145892a258696197b3feed9760187e712
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP5 BLK CD22 CD40 PARP15	2.05e-04	172	139	5	2214cc37d7c21b868768d3f74ca4631d339d37b3
ToppCell	15-Airway-Immune-Hematopoietic,_B_Cells\|Airway / Age, Tissue, Lineage and Cell class	IL10RA BLK CD22 CD40 PARP15	2.05e-04	172	139	5	36f2444754f1e37683cb812380e6b05b356f9f4a
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP5 BLK CD22 CD40 PARP15	2.05e-04	172	139	5	07620728a6cdeea805e1365e588be096c17a370c
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADGRG3 TRIM25 IRAK2 SCARF1 CD22	2.10e-04	173	139	5	5b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGRG3 TRIM25 IRAK2 SCARF1 CD22	2.10e-04	173	139	5	bf685025961e79b379f2c35464b6c8ce3e31ace0
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGRG3 TRIM25 IRAK2 SCARF1 CD22	2.10e-04	173	139	5	a6e73a40b0d5356564a594053e772f9d061a5919
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADGRG3 TRIM25 IRAK2 SCARF1 CD22	2.10e-04	173	139	5	a8b5370f4c893a20c58e97659f3ac168699693f8
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB8 BLK CD22 CD40 SDC4	2.10e-04	173	139	5	e944ea3a0a368f856efacbda4600605cf751dd9c
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADGRG3 TRIM25 IRAK2 SCARF1 CD22	2.10e-04	173	139	5	1edef5aeab626cbf2c09468e77b02cfa2d21ba03
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADGRG3 TRIM25 IRAK2 SCARF1 CD22	2.10e-04	173	139	5	c37dba3804df7c3151e18e6ae4e0b6e7a92bae97
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB8 BLK CD22 CD40 SDC4	2.10e-04	173	139	5	85fa5918e9c1f6bb4757e3350cfc71ee75c55640
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.16e-04	174	139	5	2f4bc0275cbcaa830d04a4c76e042456908d2277
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.16e-04	174	139	5	01eff218e71a04201189a0313aaf91437fffed95
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.16e-04	174	139	5	f0f6d135e1fb4c15022be103b00d8d5456515a18
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLK HMCN1 CD22 CD40 SDC4	2.28e-04	176	139	5	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	Severe_COVID-19-Myeloid-Neutrophil\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ADGRG3 TRIM25 IRAK2 SCARF1 CD22	2.34e-04	177	139	5	a6fae376f1beb1df423484d9b1bd1d954ca117af
ToppCell	COVID-19_Moderate-B_intermediate\|COVID-19_Moderate / disease group, cell group and cell class	BLK CD22 CD40 CYB5R2 PARP15	2.34e-04	177	139	5	68e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCell	NS-critical-d_07-13-Lymphoid-B_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DENND5B BLK CD22 CD40 PARP15	2.34e-04	177	139	5	d4db058c09012ec9fbde61277a9f86d9956de8fc
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP7A TFDP1 TFE3 PTPN9 TMEM168	2.34e-04	177	139	5	2dd6dd5193bda9ba1c6b299ec47890fdc92f88b1
ToppCell	mild_COVID-19_(asymptomatic)-B_memory\|World / disease group, cell group and cell class (v2)	DENND5B BLK CD22 CD40 XAF1	2.34e-04	177	139	5	057871e211c6508b2a679d391f3cf0ac7ccfc628
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TRERF1 IRAK2 NPHP4 SOX13 KMT2C	2.34e-04	177	139	5	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	NS-moderate-d_16-33-Lymphoid-B_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DENND5B BLK CD22 CD40 PARP15	2.34e-04	177	139	5	320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DENND5B BLK CD22 CD40 DNAH11	2.40e-04	178	139	5	812e261d9cbdc74fafe3c5c3422151c1cfacb22d
ToppCell	Endothelial-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	DENND5B SEMA6C PAPOLB SHROOM4 MGAT5B	2.40e-04	178	139	5	2f2602b9305d55f25afa9861dd6c6347ae179337
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.53e-04	180	139	5	243622eee35d38748e945677ff115616e763e3b4
ToppCell	Severe-Lymphoid-B\|Severe / Condition, Lineage, Cell class and cell subclass	DENND5B BLK CD22 PROX2 PARP15	2.53e-04	180	139	5	67ffaf5096f025c3c61fffe52f6c8a96f120fc6f
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.53e-04	180	139	5	3a8d9a71efe113d1df3933902a625c0a56812074
ToppCell	Severe-Lymphoid-B-\|Severe / Condition, Lineage, Cell class and cell subclass	DENND5B BLK CD22 PROX2 PARP15	2.53e-04	180	139	5	fd3eb751704b14ff1500e4bd041441644d233e9c
ToppCell	droplet-Thymus-nan-24m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.59e-04	181	139	5	2a3092fbadd18967199f1203c11f0dd956417254
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DENND5B APLP2 BLK CD22 CD40	2.59e-04	181	139	5	6df40f86c569b6ecfc3137a68d1355b012dbf6bf
ToppCell	Smart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DENND5B BLK CD22 CD40 PARP15	2.59e-04	181	139	5	768d14c452192f92fa557ae59e84c43436f575f0
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DENND5B APLP2 BLK CD22 CD40	2.59e-04	181	139	5	0c52dd82e6b3dce3d6bb5c13501bf8383f7121e4
ToppCell	facs-Heart-LV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM25 SIRT1 BLK CD22 N4BP1	2.66e-04	182	139	5	6dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DENND5B BLK CD22 CD40 PARP15	2.66e-04	182	139	5	ccd729388d997cc45071175cb0c3db6d0790eaf8
ToppCell	facs-Thymus-Flowthrough-24m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.73e-04	183	139	5	0513bb73552bfee609877d924fa97684200f595c
ToppCell	facs-Thymus-Flowthrough-24m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.73e-04	183	139	5	6eeef55071ae25a61616df4fcfb2cea560aa7923
ToppCell	facs-Thymus-Flowthrough-24m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.73e-04	183	139	5	85b2335fa938a94e74251bd8d99de1bd21265ac9
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP32 SHROOM3 LAMA3 ETV5 SDC4	2.87e-04	185	139	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 SOX13 HOXB3 TBC1D1 ZNF574	2.87e-04	185	139	5	efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 SOX13 HOXB3 TBC1D1 ZNF574	2.87e-04	185	139	5	642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell	droplet-Thymus-nan-24m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.87e-04	185	139	5	a92bd84e44fc992b7eeefaa2ff8091ed09f0df00
ToppCell	droplet-Thymus-nan-24m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.87e-04	185	139	5	877eb127ac797f8a1e1a9e0049fa16cae16cfa35
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	DENND5B APLP2 BLK CD22 CD40	2.94e-04	186	139	5	f352c63666273defea3e57ba3a3bfad52c4ea65b
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BAZ2B LAMA3 MED13L KMT2C CMIP	2.94e-04	186	139	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DENND5B APLP2 BLK CD22 CD40	2.94e-04	186	139	5	e2d265003aaea1acaf618d3f102c9933c19102e6
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IRAK2 BLK CD22 CD40 PARP15	2.94e-04	186	139	5	b5e094850ac3785775393cd78a939b02339732b0
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.94e-04	186	139	5	664295cd508dc3894d55da7e9d9cd75bf1432f52
ToppCell	BL-critical-LOC-Lymphoid-B_cell\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DENND5B BLK CD22 CD40 PARP15	2.94e-04	186	139	5	27d4c38b180e4ce2bf3e7c4ad3db3a2ffca05ca8
ToppCell	moderate-Lymphoid-B_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DENND5B BLK CD22 CD40 PARP15	2.94e-04	186	139	5	fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B BLK CD22 CD40 SDC4	2.94e-04	186	139	5	b30eb0c1673ca1ebc9b6248877d86fd6d6d14470
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DENND5B BLK CD22 CD40 PARP15	2.94e-04	186	139	5	d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCell	COVID-19_Convalescent-Lymphoid_B-B_naive\|COVID-19_Convalescent / Disease group, lineage and cell class	DENND5B APLP2 BLK CD22 CD40	2.94e-04	186	139	5	9d339f57036d17572882ebb801f2be9b1d1ddc1c
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP2 APLP2 IDE SOX13 SIRT1	5.35e-06	57	130	5	DOID:10652 (implicated_via_orthology)
Disease	Pituitary dwarfism	RNPC3 POU1F1	1.93e-05	2	130	2	C0013338
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP2 SMAD4 SMAD5	2.31e-05	13	130	3	DOID:0050787 (implicated_via_orthology)
Disease	Colonic Neoplasms	ATP7A RELA F5 BRD4 XAF1 NOTCH1	5.97e-05	152	130	6	C0009375
Disease	Malignant tumor of colon	ATP7A RELA F5 BRD4 XAF1 NOTCH1	7.66e-05	159	130	6	C0007102
Disease	Mucocutaneous Lymph Node Syndrome	BLK CD40	1.15e-04	4	130	2	C0026691
Disease	bacterial infectious disease (implicated_via_orthology)	RELA SDC4	1.91e-04	5	130	2	DOID:104 (implicated_via_orthology)
Disease	brain cancer (implicated_via_orthology)	NUMBL PROX2 NOTCH1	2.02e-04	26	130	3	DOID:1319 (implicated_via_orthology)
Disease	lymphoma (is_implicated_in)	RELA CHD4	2.86e-04	6	130	2	DOID:0060058 (is_implicated_in)
Disease	obesity (implicated_via_orthology)	ETV5 MED13L SIRT1 CD40 HSD17B3 NOTCH1	3.93e-04	215	130	6	DOID:9970 (implicated_via_orthology)
Disease	panhypopituitarism (is_implicated_in)	RNPC3 POU1F1	3.99e-04	7	130	2	DOID:9410 (is_implicated_in)
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	FER1L4 FER1L5	3.99e-04	7	130	2	DOID:11724 (implicated_via_orthology)
Disease	Acute lymphocytic leukemia	SH2B3 NOTCH1	3.99e-04	7	130	2	C0023449
Disease	atrioventricular septal defect (implicated_via_orthology)	IFT172 DNAH11	3.99e-04	7	130	2	DOID:0050651 (implicated_via_orthology)
Disease	Scoliosis, unspecified	PAX7 NOTCH1	5.30e-04	8	130	2	C0036439
Disease	Nephronophthisis	IFT172 NPHP4	6.80e-04	9	130	2	cv:C0687120
Disease	Todd Paralysis	ATP7A SIRT1	6.80e-04	9	130	2	C0234544
Disease	Liver Diseases, Parasitic	KMT2C SMAD4	6.80e-04	9	130	2	C0023897
Disease	Paralysed	ATP7A SIRT1	6.80e-04	9	130	2	C0522224
Disease	Pancreatic carcinoma, familial	PALLD SMAD4	6.80e-04	9	130	2	C2931038
Disease	Squamous cell carcinoma of esophagus	FAT3 KMT2C FAT1 NOTCH1	8.40e-04	95	130	4	C0279626
Disease	inflammatory bowel disease	SH2B3 RELA F5 DAP3 TBC1D1 CD40 POFUT1 NOTCH1	8.71e-04	449	130	8	EFO_0003767
Disease	esophagus squamous cell carcinoma (is_implicated_in)	KMT2C FAT1 COL14A1	1.04e-03	45	130	3	DOID:3748 (is_implicated_in)
Disease	ovarian serous carcinoma	LAMA3 PLEKHM1 MAGEC1	1.10e-03	46	130	3	EFO_1001516
Disease	pneumonia	IREB2 F5 TRAPPC12	1.18e-03	47	130	3	EFO_0003106
Disease	endometrial carcinoma (is_implicated_in)	MSH3 SMAD4	1.24e-03	12	130	2	DOID:2871 (is_implicated_in)
Disease	diffuse large B-cell lymphoma (is_implicated_in)	CD22 CD40	1.24e-03	12	130	2	DOID:0050745 (is_implicated_in)
Disease	iron deficiency anemia (biomarker_via_orthology)	ATP7A IREB2	1.46e-03	13	130	2	DOID:11758 (biomarker_via_orthology)
Disease	Familial thoracic aortic aneurysm and aortic dissection	SKI NOTCH1 SMAD4	1.67e-03	53	130	3	C4707243
Disease	Schizophrenia	IL10RA ARHGAP32 DRD3 NUMBL RELA CHD4 IDE SIRT1 MAGEC1 EMX2 SMAD5	1.86e-03	883	130	11	C0036341
Disease	colorectal cancer (is_implicated_in)	SH2B3 CHD4 FAT1 EMX2	2.05e-03	121	130	4	DOID:9256 (is_implicated_in)
Disease	Blood Coagulation Disorders	F5 SMAD4	2.22e-03	16	130	2	C0005779
Disease	Polyposis, Adenomatous Intestinal	MSH3 F5	2.22e-03	16	130	2	C2713442
Disease	Familial Intestinal Polyposis	MSH3 F5	2.22e-03	16	130	2	C2713443
Disease	pancreatic ductal carcinoma (is_marker_for)	CD40 PALLD SMAD4	2.50e-03	61	130	3	DOID:3587 (is_marker_for)
Disease	Amyotrophic lateral sclerosis	ALS2 FIG4	2.51e-03	17	130	2	cv:C0002736
Disease	Adenomatous Polyposis Coli	MSH3 F5	2.51e-03	17	130	2	C0032580
Disease	forced expiratory volume	TSHZ3 IREB2 SKI ZBTB24 PLEKHM1 HOXB3 FIG4 NFATC4 OTUD4 POFUT1	2.64e-03	789	130	10	EFO_0004314
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	SH2B3 BLK CD40	2.74e-03	63	130	3	EFO_0000685, EFO_0007791, EFO_0009459
Disease	noggin measurement	HIVEP2 SKI	2.81e-03	18	130	2	EFO_0021995
Disease	ovulation	SYCP2L PLEKHM1	3.14e-03	19	130	2	GO_0030728
Disease	lung non-small cell carcinoma (is_implicated_in)	RELA MSH3 KMT2C FAT1	3.39e-03	139	130	4	DOID:3908 (is_implicated_in)
Disease	colorectal adenoma (is_marker_for)	F5 SMAD4	3.47e-03	20	130	2	DOID:0050860 (is_marker_for)
Disease	atherosclerosis (biomarker_via_orthology)	SIRT1 CD40	3.47e-03	20	130	2	DOID:1936 (biomarker_via_orthology)
Disease	chronic obstructive pulmonary disease	TSHZ3 WDR64 HIVEP2 IREB2 C5orf34 HMCN1 PROX2 OTUD4 POFUT1	3.50e-03	688	130	9	EFO_0000341
Disease	epilepsy (biomarker_via_orthology)	RELA SIRT1	3.83e-03	21	130	2	DOID:1826 (biomarker_via_orthology)
Disease	pentachlorophenol measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022071
Disease	parathion measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022070
Disease	potassium chromate measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022072
Disease	mercuric chloride measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022068
Disease	heptachlor epoxide measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022067
Disease	methoxychlor measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022052
Disease	azinphos methyl measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022055
Disease	aldrin measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022054
Disease	dicofol measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022060
Disease	disulfoton measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022062
Disease	dieldrin measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022061
Disease	endrin measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022064
Disease	endosulfan measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022063
Disease	heptachlor measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022066
Disease	ethion measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022065
Disease	chlorpyrifos measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022057
Disease	cadmium chloride measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022056
Disease	diazinon measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022059
Disease	dibutyl phthalate measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0022058
Disease	environmental exposure measurement	F5 XAF1 CDC20	4.15e-03	73	130	3	EFO_0008360
Disease	Bronchiectasis	CCDC40 DNAH11	4.20e-03	22	130	2	C0006267
Disease	DDT metabolite measurement	F5 XAF1 CDC20	4.31e-03	74	130	3	EFO_0007886

Protein segments in the cluster

Peptide	Gene	Start	Entry
HSPAPPENFGNELLP	DCANP1	41	Q8TF63
HSLLQLDAPIPNAPP	CDC20	11	Q12834
TPHPFPAVTPDLIVQ	BRD4	221	O60885
APQLEFEQLPFSHPL	AACS	271	Q86V21
QPLLEEAIPNLHSPP	ALS2	371	Q96Q42
AAPPQPPHIIFILTD	ARSI	41	Q5FYB1
IPPLFAPPAQNHDSS	BAZ2B	136	Q9UIF8
PPEELQESQGLLHPQ	ARHGEF5	211	Q12774
IVAIAPLLENNHPPP	CMIP	226	Q8IY22
PLLENNHPPPDLCEF	CMIP	231	Q8IY22
PTPDEHIIPQGLLEN	DNAH11	4026	Q96DT5
PFQPVVLLHIRDVPP	PPP2R5C	21	Q13362
EPLEIVFSHQRPPPN	ADGRG3	196	Q86Y34
PPLAHPPTVFDAGLQ	AHDC1	1381	Q5TGY3
QAKAPFHTPPEEPNE	DBF4	546	Q9UBU7
FDAVIHNPDPLPVLT	ATP7A	71	Q04656
DAAPAQVAVFLPPPH	NUMBL	471	Q9Y6R0
PQKTLPDHAVPAAFP	MTUS2	216	Q5JR59
PPPLIQTAAHPNLEK	CYB5R2	251	Q6BCY4
NPAPLLVSPEVHLTP	OTUD4	571	Q01804
PDDPEHPDIFQLNNP	RALGPS1	501	Q5JS13
NTPILCPFHLQPVPE	IREB2	196	P48200
CPFHLQPVPEPETVL	IREB2	201	P48200
LPQVNGHPDPFDEII	PTPN9	251	P43378
ADLPFPLGPVHTPQL	NOBOX	451	O60393
VPPQPQADFSISPLH	PAX7	396	P23759
PFHPFPALPENEDTQ	APLP2	601	Q06481
HVNPQSFPAPKENPD	PAPOLB	416	Q9NRJ5
LPPEFSNQFESIHPP	FAT1	4451	Q14517
FPPQLPPHIATEIDR	MSH3	71	P20585
PPKNPHNPTDLFDSV	PARP15	636	Q460N3
VQSETVEPPPPAQLH	NOTCH1	1721	P46531
QLQVPEHPFLTPSPE	NOTCH1	2501	P46531
QPPLTPHPAVNESFA	KMT2C	2096	Q8NEZ4
NTVACLDHLDPPQPP	HHATL	311	Q9HCP6
QPLHFLDPLPLSQQP	MED13L	691	Q71F56
LSPLHFPQFPPQGED	MAGEC1	721	O60732
GQIPFPPASTQEPLH	LAMA3	3266	Q16787
PAFLQPPEEDAPHSL	IRAK2	151	O43187
FTPPPNDPHGIQRED	MMS19	226	Q96T76
HLTVDLPEQPYLQPP	FER1L4	991	A9Z1Z3
IGISPEPPLVQPLHF	DYNC1I1	66	O14576
LPEAHAPQSPFVLAP	MGAT5B	651	Q3V5L5
AHVELQRNPPPNSDP	FUBP3	386	Q96I24
EEPQFLLPDPHPQAD	IL10RA	331	Q13651
PDFQSDNLVLHAPPP	ETV5	71	P41161
EPGLPPTFTFHVNPV	PLA2G4F	226	Q68DD2
HPLEFADKSPTPPNL	ARHGAP32	1226	A7KAX9
PSQEHLNGPLPVPFT	SLC9A3R1	246	O14745
PHPALEPAFHLLPEN	NPHP4	191	O75161
EQLQELPFTPLHAPI	NPHP4	566	O75161
IDLQVHVPPSIAPGP	HMCN1	3796	Q96RW7
PFEVPLPAKQHVPEA	IFT172	1626	Q9UG01
VSKPLQIFHDPPLPA	MED14	366	O60244
NDHFQHFPPPPPILE	PALLD	556	Q8WX93
GNHTYQEIAVPPPVP	PXN	36	P49023
QDPPANFPLTAPSHI	PROX2	326	Q3B8N5
HFPFPAPANAPLQRI	ARAF	196	P10398
LIHSIPQFPPIPEEG	DNASE2B	141	Q8WZ79
PKPPITLDQADPFAH	FIG4	341	Q92562
APHPDQPEFTPVQDE	COL14A1	1771	Q05707
LVVFNHLTPPPPDEH	BLK	41	P51451
AQTAPPQPLELEHPT	BATF2	201	Q8N1L9
QPPPAKLLPEHAQTL	F8A1;	281	P23610
VSQEPVIPPGVPDAH	CCDC40	221	Q4G0X9
PPPHEEEFLSQDQLP	FAT3	4406	Q8TDW7
VPPQPPFQAATHLEG	HOXB3	31	P14651
AALEAPEFPLPSHQP	REXO1L1P	116	Q8IX06
TSQQPPPLPLESYIH	DENND5B	216	Q6ZUT9
DHQQPVLSDVPPLPA	AKAP5	256	P24588
PPAHPITRVPQEFQT	AKNA	421	Q7Z591
PTPHQTPYQLDPANI	MAN2B1	976	O00754
GPSPHFLQQPEDLVV	KIRREL2	21	Q6UWL6
KNVPLPEFPEHPFQE	IDE	281	P14735
SQPLNLAHVPGEEPP	HERPUD2	226	Q9BSE4
FAEAVSHPPNPAVPV	EMX2	71	Q04743
HGAASPQLEPEPQIP	EMILIN3	136	Q9NT22
DALLNNSLPPPHPEN	CHD4	21	Q14839
FEKSPPVSAHPLEQP	C5orf34	36	Q96MH7
PNLLPSHFLNAPDEI	HSD17B3	136	P37058
PEVVHPLVPLDNHIP	SDC4	76	P31431
VSERPFPPHIQLPPE	CD22	136	P20273
FPPHIQLPPEIQESQ	CD22	141	P20273
PGFPQQTLSPDPAHL	DRD3	236	P35462
LPELQPQPLLPQHDS	PANK1	201	Q8TE04
QVTYSLLPPQDPHLP	PCDHB8	486	Q9UN66
EHPVLALPGAPAQFP	POFUT1	186	Q9H488
FPELDQQLQPLPPCH	MAP3K7CL	36	P57077
IHPQFLEELLSPDPQ	NUTM2D	511	Q5VT03
VHVQEPRPQAPSPLD	PLEKHM1	371	Q9Y4G2
SPQDLETVFPHGLPP	DAP3	71	P51398
LQAPAPPHAAAEPDL	RXFP3	431	Q9NSD7
QPPLHLPLADPEVVT	SYDE1	621	Q6ZW31
NIEPVTFPHQIPSFP	TAF3	86	Q5VWG9
PSDQPSQELPQHELP	VCX3A	76	Q9NNX9
PSDQPSQELPQHELP	VCX3B	76	Q9H321
PSDQPSQELPQHELP	VCY	76	O14598
VPPEEHYQTFPIQDP	F5	1121	P12259
PTNHLSDIFPELPAP	FER1L5	2041	A0AVI2
PLEGPFPSQSDVHPL	NFATC4	821	Q14934
PLASPDPQAKHPQDL	SPATA31A6	151	Q5VVP1
PPIHQPLLAEDPTAA	POU1F1	91	P28069
PLASPDPQAKHPQDL	SPATA31A7	151	Q8IWB4
NELAFQPPISNHPAP	SMAD4	306	Q13485
FDSQPPQPVISAHPI	NEO1	1241	Q92859
PQGQVFSIDLPEHPP	SMIM28	81	A0A1B0GU29
PSLEPHFAQVPQPSV	SHROOM3	471	Q8TF72
PHEVPQILINREPLP	SIRT1	456	Q96EB6
PEEVLEQPQPLSFGH	SHROOM4	1176	Q9ULL8
PPLAEIQTQAHLSPP	SPATA31E1	516	Q6ZUB1
EGELPTHEQVFLQPP	RHPN1	371	Q8TCX5
AATEPPPVLHLPAIQ	SKI	66	P12755
PEVPFNHSFIEPPSA	SCARF1	501	Q14162
LPPVLVPRHNEFNPQ	SMAD5	136	Q99717
GEPEILPQAPANAHL	AATF	436	Q9NY61
ISAQPQLLFLHPPVP	CIPC	121	Q9C0C6
PPPNSVIHLPFIIVN	TFDP1	251	Q14186
HNVQEILGLAPPAEP	TBC1D17	586	Q9HA65
VQTPDGEQHLPQPLL	TRIM67	36	Q6ZTA4
HQPLPVTPDSQLALP	SOX13	236	Q9UN79
HPVLLPSDVFDQPQP	RNPC3	301	Q96LT9
PSDQPSQELPQHELP	VCX2	76	Q9H322
ELQAQIHGLPVPPTP	TFE3	431	P19532
QPPAPPSDALLDLHF	TFE3	491	P19532
PPENEAPPVPFLHAQ	PIGT	341	Q969N2
PLASPDPQAKHPQDL	SPATA31A1	151	Q5TZJ5
PLASPDPQAKHPQDL	SPATA31A5	151	Q5VU36
AAPPASPEPFAHIQA	TRAPPC12	271	Q8WVT3
SKFPIDHSPPQQLPF	SPATA31D1	231	Q6ZQQ2
LHLNDQSEPPVIGEP	SYCP2L	461	Q5T4T6
DSPAFQDHPLQPPVR	TRIM25	136	Q14258
HFPAPVPESQEPALQ	ZNF574	236	Q6ZN55
HFPVGNPEILPSSLP	XAF1	181	Q6GPH4
HLPEEPAPLSPQQAF	TBC1D1	576	Q86TI0
TLSHFPIECQEPPQP	TBC1D1	596	Q86TI0
PPEQIFHLVPSPEEL	SH2B3	521	Q9UQQ2
HTQAAFPQDPLPLLI	SEMA6C	21	Q9H3T2
DGQPTLLPPEHVQEL	TMEM168	426	Q9H0V1
PSDQPSQELPQHELP	VCX	76	Q9H320
DHPPEQPFVNPLSAL	TSHZ3	711	Q63HK5
DPAQHLQLTQEPGPP	ZBTB24	666	O43167
TVNPTPDPHQEYLDP	SPZ1	16	Q9BXG8
FSLPHPEALLAQQPP	GTF3C2	511	Q8WUA4
QPHLFPHQETIPFSP	HIVEP2	1186	P31629
PPVLSHPIFDNRAPN	RELA	176	Q04206
APHPKQEPQEINFPD	CD40	226	P25942
HPGIANLPEAQPPIL	WDR64	771	B1ANS9
DAPQASPISPHFPQD	TRERF1	46	Q96PN7
FPENGLHQQPEPLLP	N4BP1	521	O75113