Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	2.65e-09	26	182	7	GO:0005248
GeneOntologyMolecularFunction	sodium channel activity	PKD2L1 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	2.18e-08	52	182	8	GO:0005272
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC12A6 CACNA1E ATP13A1 SLC10A4 TRPC6 PKD2L1 ITPR2 KCNK18 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	2.75e-07	465	182	18	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1E TRPC6 PKD2L1 ITPR2 KCNK18 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	3.34e-06	343	182	14	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC12A6 CACNA1E SLC25A4 ATP13A1 SLC10A4 TRPC6 PKD2L1 GRID2 ITPR2 KCNK18 CLCN7 KCNH1 SLC19A1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	3.47e-06	793	182	22	GO:0015075
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC12A6 CACNA1E SLC25A4 ATP13A1 SLC10A4 TRPC6 PKD2L1 ITPR2 KCNK18 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	4.86e-06	627	182	19	GO:0022890
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1E TRPC6 PKD2L1 GRID2 ITPR2 KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	5.00e-06	459	182	16	GO:0005216
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN3A SCN8A	6.22e-06	14	182	4	GO:0031402
GeneOntologyMolecularFunction	channel activity	SLC12A6 CACNA1E TRPC6 PKD2L1 GRID2 ITPR2 KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	6.66e-06	525	182	17	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	SLC12A6 CACNA1E TRPC6 PKD2L1 GRID2 ITPR2 KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	6.82e-06	526	182	17	GO:0022803
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC12A6 CACNA1E SLC25A4 ATP13A1 SLC10A4 TRPC6 PKD2L1 ITPR2 KCNK18 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	1.09e-05	664	182	19	GO:0008324
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNH1 SCN1A SCN2A SCN10A	1.45e-05	17	182	4	GO:0099508
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC12A6 CACNA1E SLC25A4 ATP13A1 SLC10A4 TRPC6 PKD2L1 ITPR2 KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	2.06e-05	758	182	20	GO:0015318
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC10A4 PKD2L1 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	2.79e-05	171	182	9	GO:0015081
GeneOntologyMolecularFunction	transmembrane transporter binding	SRC EIF3E PKD2L1 ITPR2 KCNH1 ABCC8 SCN5A PKD2 SCN10A	2.92e-05	172	182	9	GO:0044325
GeneOntologyMolecularFunction	transporter activity	SLC12A6 CACNA1E GLTP SLC25A4 SLC27A6 ATP13A1 SLC10A4 TRPC6 PKD2L1 GRID2 ATP9A ATP8B2 ITPR2 SLCO1B7 KCNK18 CLCN7 KCNH1 SLC19A1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	4.37e-05	1289	182	27	GO:0005215
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1E KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN2A PKD2 SCN10A	4.55e-05	182	182	9	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1E KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN2A PKD2 SCN10A	4.96e-05	184	182	9	GO:0022832
GeneOntologyMolecularFunction	gated channel activity	CACNA1E PKD2L1 GRID2 ITPR2 KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN2A PKD2 SCN10A	5.92e-05	334	182	12	GO:0022836
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN3A SCN8A	8.53e-05	26	182	4	GO:0031420
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC12A6 CACNA1E SLC25A4 SLC27A6 ATP13A1 SLC10A4 TRPC6 PKD2L1 GRID2 ITPR2 SLCO1B7 KCNK18 CLCN7 KCNH1 SLC19A1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	1.89e-04	1180	182	24	GO:0022857
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 ABCF1 SLC27A6 ATP13A1 ZGRF1 RNF213 ATP9A ATP8B2 DDX1 ABCC8 ATP2C2 SHPRH HFM1 POLQ DNAH5	5.22e-04	614	182	15	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH3 ABCF1 ATP13A1 RNF213 ATP9A ATP8B2 DDX1 ABCC8 ATP2C2 HFM1 POLQ DNAH5	7.53e-04	441	182	12	GO:0016887
GeneOntologyMolecularFunction	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN5A SCN10A	1.21e-03	6	182	2	GO:0086006
GeneOntologyMolecularFunction	scaffold protein binding	SRC GRID2 ITPR2 SCN5A IL6ST	1.62e-03	93	182	5	GO:0097110
GeneOntologyMolecularFunction	guanylyltransferase activity	RNGTT FPGT	1.68e-03	7	182	2	GO:0070568
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PDCD6 NMNAT1 PRAMEF19 PRAMEF18 AXIN1	1.78e-03	95	182	5	GO:0140767
GeneOntologyBiologicalProcess	transmission of nerve impulse	CACNA1E DPP6 GHSR SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	6.39e-07	112	181	9	GO:0019226
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	6.58e-07	36	181	6	GO:0086010
GeneOntologyBiologicalProcess	neuronal action potential	DPP6 SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.30e-06	63	181	7	GO:0019228
GeneOntologyBiologicalProcess	membrane depolarization	SRC SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A KDR	1.17e-05	121	181	8	GO:0051899
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC12A6 CACNA1E DPP6 KLHL24 SLC25A4 ATP13A1 TRPC6 PKD2L1 GRID2 ATP8B2 ITPR2 KCNK18 CLCN7 TMEM168 KCNH1 SLC19A1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	1.53e-05	1115	181	25	GO:0034220
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	KLHL24 PKD2L1 TMEM168 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	1.58e-05	208	181	10	GO:0035725
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.72e-05	62	181	6	GO:0086002
GeneOntologyBiologicalProcess	positive regulation of response to food	OR4M1 GHSR OR4M2	2.27e-05	7	181	3	GO:0032097
GeneOntologyBiologicalProcess	positive regulation of appetite	OR4M1 GHSR OR4M2	2.27e-05	7	181	3	GO:0032100
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC12A6 CACNA1E DPP6 KLHL24 SLC25A4 ATP13A1 SLC10A4 TRPC6 PKD2L1 GRID2 TF ATP8B2 ITPR2 SLCO1B7 KCNK18 CLCN7 TMEM168 KCNH1 SLC19A1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	2.57e-05	1374	181	28	GO:0006811
GeneOntologyBiologicalProcess	sodium ion transport	KLHL24 SLC10A4 PKD2L1 TMEM168 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	3.29e-05	275	181	11	GO:0006814
GeneOntologyBiologicalProcess	positive regulation of response to nutrient levels	OR4M1 GHSR OR4M2	3.60e-05	8	181	3	GO:0032109
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC12A6 CACNA1E DPP6 KLHL24 SLC25A4 ATP13A1 TRPC6 PKD2L1 ITPR2 KCNK18 TMEM168 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	6.21e-05	922	181	21	GO:0098662
GeneOntologyBiologicalProcess	metal ion transport	SLC12A6 CACNA1E DPP6 KLHL24 ATP13A1 SLC10A4 TRPC6 PKD2L1 TF ITPR2 KCNK18 TMEM168 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	6.85e-05	1000	181	22	GO:0030001
GeneOntologyBiologicalProcess	response to pH	SRC PKD2L1 KCNK18 CLCN7 ABCC8	6.87e-05	49	181	5	GO:0009268
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC12A6 CACNA1E DPP6 KLHL24 SLC25A4 ATP13A1 TRPC6 PKD2L1 ITPR2 KCNK18 TMEM168 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	8.42e-05	942	181	21	GO:0098655
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC12A6 CACNA1E DPP6 KLHL24 SLC25A4 ATP13A1 TRPC6 PKD2L1 ITPR2 KCNK18 CLCN7 TMEM168 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	8.76e-05	1017	181	22	GO:0098660
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.18e-04	87	181	6	GO:0086001
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.70e-04	93	181	6	GO:0086003
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC12A6 CACNA1E DPP6 KLHL24 SLC25A4 ATP13A1 SLC10A4 TRPC6 PKD2L1 TF ITPR2 KCNK18 TMEM168 KCNH1 ABCC8 SCN1A SCN2A SCN3A ATP2C2 SCN5A SCN8A PKD2 SCN10A	2.09e-04	1157	181	23	GO:0006812
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	4.43e-09	17	181	6	GO:0001518
GeneOntologyCellularComponent	cation channel complex	CACNA1E DPP6 TRPC6 PKD2L1 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	1.43e-07	235	181	13	GO:0034703
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.56e-07	29	181	6	GO:0034706
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1E DPP6 TRPC6 PKD2L1 GRID2 NRN1 CLCN7 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	2.03e-07	378	181	16	GO:0034702
GeneOntologyCellularComponent	transporter complex	CACNA1E DPP6 TRPC6 PKD2L1 GRID2 NRN1 ATP8B2 CLCN7 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	6.28e-06	550	181	17	GO:1990351
GeneOntologyCellularComponent	transmembrane transporter complex	CACNA1E DPP6 TRPC6 PKD2L1 GRID2 NRN1 CLCN7 KCNH1 ABCC8 SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	1.35e-05	523	181	16	GO:1902495
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A SCN8A	6.53e-04	20	181	3	GO:0033268
HumanPheno	Arachnoid cyst	AXIN1 SCN1A SCN2A ALG5 PKD2 GPSM2 CPLANE1	1.29e-05	58	71	7	HP:0100702
HumanPheno	Abnormal arachnoid mater morphology	AXIN1 SCN1A SCN2A ALG5 PKD2 GPSM2 CPLANE1	1.45e-05	59	71	7	HP:0100700
Domain	Na_channel_asu	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.45e-10	10	179	6	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.45e-10	10	179	6	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.45e-10	10	179	6	PF06512
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN5A SCN8A	4.55e-10	6	179	5	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN5A SCN8A	4.55e-10	6	179	5	IPR024583
Domain	Channel_four-helix_dom	CACNA1E SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	6.74e-08	57	179	8	IPR027359
Domain	-	CACNA1E SCN1A SCN2A SCN3A SCN5A SCN8A PKD2 SCN10A	6.74e-08	57	179	8	1.20.120.350
Domain	Ion_trans_dom	CACNA1E TRPC6 ITPR2 KCNH1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.46e-07	114	179	10	IPR005821
Domain	Ion_trans	CACNA1E TRPC6 ITPR2 KCNH1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.46e-07	114	179	10	PF00520
Domain	ARM-type_fold	INTS7 DOCK8 CIP2A USP24 USP9Y ITPR2 INF2 INSC IPO13 RIC8A UNC79 STAG2 HEATR3 IPO11	5.13e-06	339	179	14	IPR016024
Domain	IQ_motif_EF-hand-BS	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A MYO16	2.53e-05	90	179	7	IPR000048
Domain	IQ	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A MYO16	3.13e-05	93	179	7	PS50096
Domain	ARM-like	RANGAP1 INTS7 DOCK8 CIP2A USP9Y INSC IPO13 RIC8A STAG2 HEATR3 IPO11	6.12e-05	270	179	11	IPR011989
Domain	NAD/GMP_synthase	GMPS NADSYN1	9.13e-05	2	179	2	IPR022310
Domain	NAD_synthase	GMPS NADSYN1	9.13e-05	2	179	2	PF02540
Domain	IQ	SCN1A SCN2A SCN3A SCN5A SCN8A MYO16	1.28e-04	81	179	6	SM00015
Domain	ATPase_P-typ_cyto_domN	ATP13A1 ATP9A ATP8B2 ATP2C2	3.39e-04	35	179	4	IPR023299
Domain	ATPase_P-typ_P_site	ATP13A1 ATP9A ATP8B2 ATP2C2	3.78e-04	36	179	4	IPR018303
Domain	P_typ_ATPase	ATP13A1 ATP9A ATP8B2 ATP2C2	3.78e-04	36	179	4	IPR001757
Domain	ATPASE_E1_E2	ATP13A1 ATP9A ATP8B2 ATP2C2	3.78e-04	36	179	4	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP13A1 ATP9A ATP8B2 ATP2C2	4.21e-04	37	179	4	IPR008250
Domain	E1-E2_ATPase	ATP13A1 ATP9A ATP8B2 ATP2C2	4.21e-04	37	179	4	PF00122
Domain	PKD_2	PKD2L1 PKD2	8.96e-04	5	179	2	IPR003915
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	5.62e-07	31	142	6	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	6.86e-07	32	142	6	M27455
Pathway	REACTOME_L1CAM_INTERACTIONS	SRC SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A RPS6KA6	3.00e-05	121	142	8	M872
Pathway	REACTOME_CARDIAC_CONDUCTION	ITPR2 KCNK18 SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	5.02e-05	130	142	8	M27454
Pathway	WP_DRAVET_SYNDROME	SCN1A SCN2A SCN3A SCN8A	1.67e-04	28	142	4	M45519
Pathway	WP_NETRINUNC5B_SIGNALING	CIP2A NTN3 SRC RLF KDR	1.72e-04	52	142	5	M39782
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	1.62e-12	9	183	6	16382098
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN3A SCN8A SCN10A	2.28e-11	6	183	5	23652591
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	3.25e-11	13	183	6	15123669
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN3A SCN5A SCN8A	4.73e-10	9	183	5	15746173
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN3A SCN8A	7.42e-10	4	183	4	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN3A SCN8A	7.42e-10	4	183	4	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN3A SCN8A	7.42e-10	4	183	4	29578003
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN2A SCN3A SCN5A SCN8A	2.93e-09	12	183	5	30175250
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN3A SCN5A SCN8A	3.69e-09	5	183	4	17724025
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1E KCNK18 CLCN7 KCNH1 ABCC8 SCN1A SCN3A SCN5A SCN8A SCN10A	3.77e-09	139	183	10	16985003
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A SCN3A	1.43e-07	3	183	3	23859570
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A SCN3A	1.43e-07	3	183	3	12610651
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A SCN3A	1.43e-07	3	183	3	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A SCN3A	1.43e-07	3	183	3	17544618
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A SCN8A	1.43e-07	3	183	3	32845893
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A SCN8A	1.43e-07	3	183	3	28518218
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A SCN8A	1.43e-07	3	183	3	17928448
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A SCN3A	1.43e-07	3	183	3	14973256
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN2A SCN3A	5.71e-07	4	183	3	35801810
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A SCN8A	5.71e-07	4	183	3	21156207
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN2A SCN3A	5.71e-07	4	183	3	8974318
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	EPHB4 RANGAP1 COPA HACD3 INTS7 ATP13A1 CIP2A USP24 ATP9A DDX1 STT3B TTLL12 INF2 SLC19A1 ALG5 RIC8A STAG2 HEATR3 IPO11	6.51e-07	942	183	19	31073040
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SLC12A6 ATRN ATF7 DPP6 TIGAR HACD3 VPS13C SRC RNF213 INTS3 TASOR2 GMPS RLF RAB28 ASAP2 NADSYN1 GRK3 INF2 SLC19A1 ABCC8 PKD2 SHPRH SPIDR STAG2	1.15e-06	1489	183	24	28611215
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN2A SCN3A	1.42e-06	5	183	3	1679748
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN2A SCN3A	1.42e-06	5	183	3	8812438
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN3A SCN5A SCN8A	1.42e-06	5	183	3	22875929
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN2A SCN3A	1.42e-06	5	183	3	24337656
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ATRN DNAH3 RANGAP1 RNGTT HACD3 VPS13C MUC19 RNF213 ITPR2 GMPS TTLL12 NUDT12 SCN3A SCN8A MAPK9 HEATR3	2.01e-06	736	183	16	29676528
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	TRAF7 LETMD1 INTS7 ATP13A1 EIF3E COMMD5 ASCC1 TRMT1 TMEM43 STT3B ALG5 IPO13 IL17RA HERC2 HEATR3 IPO11	2.73e-06	754	183	16	33060197
Pubmed	An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.	SCN3A SCN8A SCN10A	2.83e-06	6	183	3	23711479
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN2A SCN8A	4.94e-06	7	183	3	25818041
Pubmed	Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.	SCN1A SCN5A SCN8A	4.94e-06	7	183	3	15272007
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPHB4 TRAF7 SETD1A ATP13A1 TRMT1 RAPGEF1 ITPR2 FZD1 LPIN3 NADSYN1 CLCN7 INF2 SCN5A SCN8A TXNRD3 RIC8A HERC2 HERC1 RAD9A	6.60e-06	1105	183	19	35748872
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ATF7 RANGAP1 PDCD6 COPA HACD3 CIP2A EIF3E ASCC1 CASP7 RNF213 TMEM43 PSME1 DDX1 STT3B ITPR2 INF2 ALG5 SYNE2 IPO13 STAG2 HEATR3 IPO11	7.79e-06	1440	183	22	30833792
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	EPHB4 SETD1A NMNAT1 SRC CAPN6 USP24 STT3B CAPN11 ADAMTS12 KCNH1 ATP2C2 RPS6KA6 MAPK4 DNAH5 KDM1A	8.31e-06	730	183	15	34857952
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	RNGTT COPA EIF3E ITPR2 RIC8A HERC2 HERC1	9.46e-06	139	183	7	25476789
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	MMS22L RANGAP1 COPA HACD3 CIP2A TAB2 TMEM43 STT3B VANGL1 IPO13 OTUD4 HERC2 HEATR3 IPO11	1.12e-05	657	183	14	36180527
Pubmed	Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.	SCN1A SCN5A SCN8A	1.18e-05	9	183	3	17884088
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RANGAP1 RNGTT COPA CIP2A RNF213 TAB2 PSME1 ITPR2 GMPS NUDT12 CACTIN CLCN7 VANGL1 SYNE2 OTUD4 HERC2 HERC1 MAPK9	1.20e-05	1049	183	18	27880917
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB4 TRAF7 ATRN ABCF1 COPA HACD3 MATN2 RNF213 TMEM43 ATP9A DDX1 STT3B ITPR2 MESD PKD2 DPY19L4 IPO13 UHRF1 IL6ST	2.10e-05	1201	183	19	35696571
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ATF7 ABCF1 RNGTT GLTP PDCD6 DOCK8 PSME1 TDP2 DDX1 GMPS TTLL12 RLF MED28 PRPF39 STAG2 HEATR3 KDM1A IPO11	2.34e-05	1103	183	18	34189442
Pubmed	A common genetic variant within SCN10A modulates cardiac SCN5A expression.	SCN5A SCN10A	2.75e-05	2	183	2	24642470
Pubmed	Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferation.	SRC KDR	2.75e-05	2	183	2	16322069
Pubmed	Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.	SCN2A SCN3A	2.75e-05	2	183	2	20346423
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	2.75e-05	2	183	2	37901435
Pubmed	An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.	SCN1A SCN8A	2.75e-05	2	183	2	26410685
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	2.75e-05	2	183	2	10827969
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	2.75e-05	2	183	2	19694741
Pubmed	Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.	SCN2A SCN8A	2.75e-05	2	183	2	35348308
Pubmed	Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.	SCN2A SCN3A	2.75e-05	2	183	2	11245985
Pubmed	Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.	SCN5A SCN10A	2.75e-05	2	183	2	15047701
Pubmed	Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.	SCN2A SCN8A	2.75e-05	2	183	2	15760941
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	2.75e-05	2	183	2	1317301
Pubmed	Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.	SCN2A SCN3A	2.75e-05	2	183	2	23016767
Pubmed	Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy.	SCN1A IL17RA	2.75e-05	2	183	2	29487082
Pubmed	Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.	SCN2A SCN3A	2.75e-05	2	183	2	27153334
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	2.75e-05	2	183	2	24990319
Pubmed	VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability.	SRC KDR	2.75e-05	2	183	2	21177802
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	2.75e-05	2	183	2	31439038
Pubmed	Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.	PKD2L1 PKD2	2.75e-05	2	183	2	29899465
Pubmed	Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.	SCN1A SCN8A	2.75e-05	2	183	2	31943325
Pubmed	Insc:LGN tetramers promote asymmetric divisions of mammary stem cells.	INSC GPSM2	2.75e-05	2	183	2	29523789
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	2.75e-05	2	183	2	15249644
Pubmed	Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2.	PKD2L1 PKD2	2.75e-05	2	183	2	20408813
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	2.75e-05	2	183	2	27690330
Pubmed	Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.	SCN2A SCN8A	2.75e-05	2	183	2	18601978
Pubmed	Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.	SCN5A SCN10A	2.75e-05	2	183	2	24998131
Pubmed	Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a.	SETD1A UHRF1	2.75e-05	2	183	2	29968706
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	2.75e-05	2	183	2	23965409
Pubmed	FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.	SCN2A SCN8A	2.75e-05	2	183	2	19465131
Pubmed	Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.	SCN2A SCN5A	2.75e-05	2	183	2	16847056
Pubmed	From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.	SCN5A SCN10A	2.75e-05	2	183	2	24360055
Pubmed	The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state.	SETD1A KDM1A	2.75e-05	2	183	2	27174370
Pubmed	Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation.	SRC CASP7	2.75e-05	2	183	2	24407236
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	2.75e-05	2	183	2	30693367
Pubmed	Regulation of an ERG K+ current by Src tyrosine kinase.	SRC KCNH1	2.75e-05	2	183	2	11834728
Pubmed	Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.	SCN2A SCN8A	2.75e-05	2	183	2	23735284
Pubmed	Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.	SCN5A SCN10A	2.75e-05	2	183	2	32330377
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	2.75e-05	2	183	2	29649454
Pubmed	Programmed cell death 6 (PDCD6) inhibits angiogenesis through PI3K/mTOR/p70S6K pathway by interacting of VEGFR-2.	PDCD6 KDR	2.75e-05	2	183	2	21893193
Pubmed	Calpain-calpastatin: a novel, complete calcium-dependent protease system in human spermatozoa.	CAPN6 CAPN11	2.75e-05	2	183	2	10340998
Pubmed	Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1.	SETD1A UHRF1	2.75e-05	2	183	2	33938913
Pubmed	Role of the ATFa/JNK2 complex in Jun activation.	ATF7 MAPK9	2.75e-05	2	183	2	10376527
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	2.75e-05	2	183	2	33096315
Pubmed	Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.	SCN5A SCN10A	2.75e-05	2	183	2	31292628
Pubmed	Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src.	SRC KDR	2.75e-05	2	183	2	10455194
Pubmed	Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.	SCN1A SCN5A	2.75e-05	2	183	2	16054936
Pubmed	Sodium channel expression within chronic multiple sclerosis plaques.	SCN2A SCN8A	2.75e-05	2	183	2	17805013
Pubmed	Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.	SCN1A SCN5A	2.75e-05	2	183	2	33712547
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	2.75e-05	2	183	2	26311622
Pubmed	Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.	SCN1A SCN8A	2.75e-05	2	183	2	33411788
Pubmed	In vivo association of ATFa with JNK/SAP kinase activities.	ATF7 MAPK9	2.75e-05	2	183	2	8649858
Pubmed	The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.	SCN1A SCN2A	2.75e-05	2	183	2	21377452
Pubmed	Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.	SCN1A SCN8A	2.75e-05	2	183	2	37665666
Pubmed	The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.	SCN1A SCN8A	2.75e-05	2	183	2	17881658
Pubmed	A high-density association screen of 155 ion transport genes for involvement with common migraine.	CACNA1E ATP2C2 SCN5A	3.04e-05	12	183	3	18676988
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	SCN1A SCN2A SCN3A	3.04e-05	12	183	3	8169823
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	RANGAP1 ABCF1 ATP13A1 TMEM43 STT3B ITPR2 CLCN7 INF2 VANGL1 SYNE2	3.27e-05	375	183	10	32788342
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANGAP1 COPA HACD3 CIP2A EIF3E USP24 DDX1 GMPS TTLL12 RIC8A STAG2 KDM1A IPO11	3.68e-05	638	183	13	33239621
Pubmed	A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.	INTS7 INTS3 RAD9A	3.94e-05	13	183	3	21659603
Interaction	SIGLECL1 interactions	CIP2A RNF213 INTS3 NRN1 IPO13 STAG2 HEATR3 IPO11	6.22e-06	113	174	8	int:SIGLECL1
Interaction	SCN11A interactions	SCN1A SCN5A SCN8A SCN10A	6.80e-06	15	174	4	int:SCN11A
Cytoband	15q13	SLC12A6 MESD HERC2	5.14e-06	9	183	3	15q13
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	9.24e-12	9	128	6	1203
GeneFamily	Transient receptor potential cation channels	TRPC6 PKD2L1 PKD2	9.98e-04	28	128	3	249
GeneFamily	Zinc fingers GRF-type\|Topoisomerases	ZGRF1 ZCCHC4	1.02e-03	7	128	2	135
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_500	CHM GMPS RLF SYNE2 HERC1 CPLANE1	1.68e-06	45	173	6	gudmap_developingGonad_e16.5_epididymis_500_k3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000	CIP2A RNF213 CHM GMPS RLF SYNE2 NR5A2 HERC1 CPLANE1	2.00e-06	138	173	9	gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500	SETD1A COPA CHM GMPS RLF SYNE2 HERC1 CPLANE1	2.71e-06	107	173	8	gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500	SETD1A COPA CHM RLF SYNE2 CPLANE1	1.49e-05	65	173	6	gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500	SETD1A COPA CHM GMPS RLF SYNE2 CPLANE1	1.91e-05	101	173	7	gudmap_developingGonad_e14.5_ ovary_500_k1
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	CIP2A RNF213 CHM GMPS RLF SYNE2 SHPRH SPIDR HERC1 CPLANE1	2.23e-05	233	173	10	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	SLC12A6 SETD1A COPA CIP2A CHDH RNF213 GRID2 CHM NRN1 ITPR2 GMPS RLF SYNE2 ATP2C2 NR5A2 TXNRD3 HERC1 CPLANE1	6.04e-05	770	173	18	gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500	SLC12A6 SETD1A COPA CHDH GRID2 CHM GMPS RLF SYNE2 NR5A2 HERC1 CPLANE1	6.79e-05	379	173	12	gudmap_developingGonad_P2_ovary_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	SETD1A COPA CHM GMPS RLF SYNE2 PKD2 KDR HERC1 CPLANE1	8.99e-05	275	173	10	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_1000	CHM GMPS RLF SYNE2 HERC1 CPLANE1	9.48e-05	90	173	6	gudmap_developingGonad_P2_epididymis_1000_k4
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_1000	CHM GMPS RLF SYNE2 HERC1 CPLANE1	1.44e-04	97	173	6	gudmap_developingGonad_e18.5_epididymis_1000_k4
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	MMS22L SLC27A6 HACD3 CIP2A MATN2 TRPC6 CAPN6 RNF213 NRN1 LDB2 STT3B ADAMTS12 SCN2A SYNE2 RPS6KA6 UHRF1 KDR SPIDR	1.48e-04	827	173	18	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_500	CHM GMPS RLF SYNE2 HERC1	2.18e-04	67	173	5	gudmap_developingGonad_e18.5_epididymis_500_k3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500	SETD1A COPA CHM GMPS RLF SYNE2 HERC1	2.34e-04	150	173	7	gudmap_developingGonad_e12.5_epididymis_k5_500
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DPP6 USP24 CSMD3 ABCC8 SCN1A SCN2A ATP2C2 UNC79 HYDIN	1.38e-07	199	182	9	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 CHDH NRN1 CSMD3 CTXND1 NUDT12 INSC UNC79	1.06e-06	187	182	8	16e55d802fc4e71878305e61ad03806aabd59537
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C USP24 RNF213 TASOR2 RLF SYNE2 HERC1 IL6ST	1.10e-06	188	182	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PKD2L1 KCNH1 SCN2A TXNRD3 HFM1 UNC79 HYDIN TPH1	1.39e-06	194	182	8	2dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MMS22L CELF4 ZGRF1 VSIG1 SCN1A UHRF1 MAPK4 POLQ	1.56e-06	197	182	8	49689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH3 DNAAF11 RAB36 C6orf118 ATP2C2 UHRF1 DNAH5 HYDIN	1.62e-06	198	182	8	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH3 MMS22L DNAAF11 RAB36 C6orf118 ATP2C2 DNAH5 HYDIN	1.68e-06	199	182	8	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1E CELF4 ATP9A NRN1 ABRACL CAMKV SCN3A UNC79	1.75e-06	200	182	8	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPP6 GRID2 CSMD3 SGCZ SCN1A SCN2A SCN3A MYO16	1.75e-06	200	182	8	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPP6 GRID2 CSMD3 SGCZ SCN1A SCN2A SCN3A MYO16	1.75e-06	200	182	8	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CELF4 CSMD3 KCNH1 SCN2A SCN3A SCN8A HERC1 UNC79	1.75e-06	200	182	8	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPP6 GRID2 CSMD3 SGCZ SCN1A SCN2A SCN3A MYO16	1.75e-06	200	182	8	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1E CELF4 ATP9A NRN1 ABRACL CAMKV SCN3A UNC79	1.75e-06	200	182	8	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPP6 GRID2 CSMD3 SGCZ SCN1A SCN2A SCN3A MYO16	1.75e-06	200	182	8	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPP6 GRID2 CSMD3 SGCZ SCN1A SCN2A SCN3A MYO16	1.75e-06	200	182	8	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPP6 GRID2 CSMD3 SGCZ SCN1A SCN2A SCN3A MYO16	1.75e-06	200	182	8	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CACNA1E DNAH3 DOCK8 RUBCNL TRMT1 OR2T11 KDR	3.12e-06	152	182	7	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPA12B NRN1 LDB2 SCN3A SCN5A KDR IPO11	5.57e-06	166	182	7	5ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPA12B NRN1 LDB2 SCN3A SCN5A KDR IPO11	5.57e-06	166	182	7	6bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTN3 FAM83C TTLL12 CAMKV DENND2C ATP2C2 POLQ	6.51e-06	170	182	7	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	ASK452-Endothelial-Lymphatic\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	CIP2A NRN1 LDB2 PRPF40B SCN3A IPO13 KDR	8.17e-06	176	182	7	b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 NTN3 GRID2 NRN1 CTXND1 KCNH1 INSC	9.81e-06	181	182	7	0b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CHDH CASP7 OAS1 RNF213 HSPA12B LDB2 KDR	1.05e-05	183	182	7	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MATN2 TRPC6 GRID2 ADAMTS12 SGCZ INSC HFM1	1.13e-05	185	182	7	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 NRN1 CSMD3 FZD1 CTXND1 INSC UNC79	1.17e-05	186	182	7	d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	MMS22L DOCK8 VPS13C RNF213 ITPR2 SHPRH POLQ	1.17e-05	186	182	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 NRN1 CSMD3 FZD1 CTXND1 INSC GPSM2	1.21e-05	187	182	7	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 NRN1 CSMD3 FZD1 CTXND1 INSC GPSM2	1.21e-05	187	182	7	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	droplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MMS22L CENPA INTS7 CIP2A UHRF1 POLQ C4orf46	1.25e-05	188	182	7	0ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MMS22L CENPA ZGRF1 CIP2A UHRF1 GPSM2 POLQ	1.30e-05	189	182	7	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 NRN1 CSMD3 FZD1 CTXND1 INSC UNC79	1.34e-05	190	182	7	ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	RAPGEF1 LDB2 ADAMTS12 ASAP2 SYNE2 SCN3A KDR	1.34e-05	190	182	7	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATN2 NRN1 CSMD3 FZD1 CTXND1 INSC UNC79	1.34e-05	190	182	7	4971857eac9af17d66d673ed2ab7072639f60a10
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	DNAH3 CFAP251 RAB36 C6orf118 ATP2C2 DNAH5 HYDIN	1.39e-05	191	182	7	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	DNAH3 CFAP251 RAB36 C6orf118 ATP2C2 DNAH5 HYDIN	1.39e-05	191	182	7	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	11.5-Airway-Epithelial-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	CACNA1E DPP6 SLC10A4 CAMKV SCN2A SCN3A SCN5A	1.44e-05	192	182	7	a77d3692ff02ef7e066a9bd9e22725055a25c4d4
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	EPHB4 RAPGEF1 HSPA12B LDB2 SYNE2 NR5A2 KDR	1.44e-05	192	182	7	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 CFAP251 C6orf118 ATP2C2 CPLANE1 DNAH5 HYDIN	1.49e-05	193	182	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MMS22L NMNAT1 CSMD3 CAMKV TXNRD3 IPO13 MYO16	1.49e-05	193	182	7	088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	EPHB4 RAPGEF1 HSPA12B LDB2 SYNE2 NR5A2 KDR	1.49e-05	193	182	7	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	EPHB4 RAPGEF1 HSPA12B LDB2 SYNE2 NR5A2 KDR	1.54e-05	194	182	7	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 CFAP251 DNAAF11 RAB36 C6orf118 DNAH5 HYDIN	1.54e-05	194	182	7	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CELF4 SLC27A6 MATN2 CAPN6 TF MYO16 IL6ST	1.59e-05	195	182	7	1be9502577267ca2a04656a99d57e3e2f124d92e
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	DPP6 CELF4 SLC25A4 LDB2 ABRACL CAMKV SCN2A	1.59e-05	195	182	7	574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 CFAP251 RAB36 C6orf118 CPLANE1 DNAH5 HYDIN	1.59e-05	195	182	7	79dc031258579ea328181dda33710dd897f1064a
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 DNAAF11 RAB36 C6orf118 ATP2C2 DNAH5 HYDIN	1.59e-05	195	182	7	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CELF4 CSMD3 KCNH1 SCN2A SCN3A SCN8A UNC79	1.64e-05	196	182	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 CFAP251 DNAAF11 RAB36 C6orf118 DNAH5 HYDIN	1.64e-05	196	182	7	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MATN2 HSPA12B NRN1 LDB2 CAPN11 NR5A2 KDR	1.70e-05	197	182	7	78bc83cd5546c7dd128e6791acda97f55089bc1c
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHB4 HSPA12B NRN1 LDB2 CAPN11 ABCC8 IL6ST	1.70e-05	197	182	7	8437c33e2c4a10a1b95343431e48d5e820b1f742
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 HSPA12B NRN1 LDB2 NR5A2 KDR IPO11	1.70e-05	197	182	7	7caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 CFAP251 C6orf118 SYNE2 CPLANE1 DNAH5 HYDIN	1.70e-05	197	182	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHB4 HSPA12B NRN1 LDB2 CAPN11 ABCC8 IL6ST	1.70e-05	197	182	7	0542badae77d2f606c13cfaf361319495c354351
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 HSPA12B NRN1 LDB2 NR5A2 KDR IPO11	1.70e-05	197	182	7	951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell	distal-3-Epithelial-Proximal_Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 CFAP251 FAM83C RAB36 C6orf118 DNAH5 HYDIN	1.70e-05	197	182	7	15b4d1203943ce90a7083178d4a4284d9b323071
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHB4 HSPA12B NRN1 LDB2 CAPN11 ABCC8 IL6ST	1.70e-05	197	182	7	a6a64581699cfcb9607b288976fa3b09648725b7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CELF4 CSMD3 SCN1A SCN2A SCN3A SCN8A UNC79	1.75e-05	198	182	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CELF4 CSMD3 SCN1A SCN2A SCN3A SCN8A UNC79	1.75e-05	198	182	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CELF4 CSMD3 SCN1A SCN2A SCN3A SCN8A UNC79	1.75e-05	198	182	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH3 CELF4 TF RAB36 KDR DNAH5 HYDIN	1.75e-05	198	182	7	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH3 CELF4 TF RAB36 KDR DNAH5 HYDIN	1.75e-05	198	182	7	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CELF4 CSMD3 SCN2A SCN3A SCN8A HERC1 UNC79	1.75e-05	198	182	7	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	COVID-19-kidney-Epithelial_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MUC19 GRID2 CSMD3 LDB2 GHSR SGCZ	1.81e-05	133	182	6	a8abb6b54862123961ae6defbf251ee6e9575258
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 HSPA12B NRN1 LDB2 SCN3A KDR IPO11	1.81e-05	199	182	7	1587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 HSPA12B NRN1 LDB2 SCN3A KDR IPO11	1.81e-05	199	182	7	a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MMS22L CENPA ZGRF1 CIP2A SYNE2 UHRF1 POLQ	1.81e-05	199	182	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	EPHB4 RNF213 HSPA12B LDB2 ASAP2 SYNE2 KDR	1.87e-05	200	182	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	EPHB4 RNF213 LDB2 ASAP2 SYNE2 NR5A2 KDR	1.87e-05	200	182	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	EPHB4 RNF213 HSPA12B LDB2 ASAP2 SYNE2 KDR	1.87e-05	200	182	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	OAS1 RNF213 USP9Y ATP8B2 SYNE2 CD96 IL6ST	1.87e-05	200	182	7	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	EPHB4 HSPA12B LDB2 ASAP2 SYNE2 NR5A2 KDR	1.87e-05	200	182	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKD2L1 USP9Y CSMD3 SCN1A SCN10A HYDIN	2.94e-05	145	182	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC6 ADAMTS12 NUDT12 PRPF40B ATP2C2 PKD2	3.84e-05	152	182	6	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC6 ADAMTS12 NUDT12 PRPF40B ATP2C2 PKD2	3.84e-05	152	182	6	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAAF11 RAB36 ATP2C2 DNAH5 HYDIN	4.13e-05	154	182	6	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAAF11 RAB36 ATP2C2 DNAH5 HYDIN	4.13e-05	154	182	6	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 GRID2 CSMD3 SGCZ KIRREL3 MYO16	4.93e-05	159	182	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	VPS13C ZFP28 PRAMEF18 ITIH1 GRK3 SCN1A	4.93e-05	159	182	6	1dde4d19cc0fde7ebbccb4c31bb845a92206021b
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CIP2A PKD2L1 USP9Y CSMD3 SCN10A HYDIN	5.47e-05	162	182	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 GRID2 CSMD3 SGCZ CD96 MYO16	5.66e-05	163	182	6	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC10A4 SCN1A SCN3A SCN5A NR5A2 KDR	6.06e-05	165	182	6	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC10A4 SCN1A SCN3A SCN5A NR5A2 KDR	6.06e-05	165	182	6	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC10A4 SCN1A SCN3A SCN5A NR5A2 KDR	6.06e-05	165	182	6	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CELF4 GRID2 CSMD3 KIRREL3 SCN2A DNAH5	6.06e-05	165	182	6	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC10A4 SCN1A SCN3A SCN5A NR5A2 KDR	6.06e-05	165	182	6	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MMS22L ZGRF1 CIP2A SCN2A UHRF1 POLQ	6.92e-05	169	182	6	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MMS22L ZGRF1 ASB16 UHRF1 MAPK4 POLQ	6.92e-05	169	182	6	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 CFAP251 DNAAF11 C6orf118 DNAH5 HYDIN	6.92e-05	169	182	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB4 PKD2L1 SCN1A SCN3A KDR IPO11	7.15e-05	170	182	6	35e3945d8a540a3e2cec1b559316265aaad023d1
ToppCell	PND01-Endothelial-Endothelial_lymphatic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB4 PKD2L1 SCN1A SCN3A KDR IPO11	7.15e-05	170	182	6	0ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB4 PKD2L1 SCN1A SCN3A KDR IPO11	7.15e-05	170	182	6	0b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Cldn11_(Cldn11)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CHDH PKD2L1 NR5A2 SPIDR POLQ	7.47e-05	106	182	5	5e01b9dd76a2f5904100de603310e6c0a553fbda
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Cldn11_(Cldn11)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CHDH PKD2L1 NR5A2 SPIDR POLQ	7.47e-05	106	182	5	be9de0f664395079fef9f3bbdffa651ea6f58be2
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MMS22L HSPA12B VANGL1 UHRF1 POLQ PRPF39	7.62e-05	172	182	6	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ATF7 ATP13A1 ATP8B2 TASOR2 CACTIN UHRF1	7.62e-05	172	182	6	da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SLC12A6 ATRN TTLL12 NUDT12 PKD2 HEATR3	7.87e-05	173	182	6	efb8072475000888efe088d00e870c56ffad4172
ToppCell	Endothelial-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	HSPA12B NRN1 LDB2 SCN3A KDR IPO11	7.87e-05	173	182	6	a81992965137195d20fc498f750975303961a828
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SLC12A6 ATRN TTLL12 NUDT12 PKD2 HEATR3	8.12e-05	174	182	6	58300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPA12B NRN1 LDB2 ADAMTS12 KDR IPO11	8.93e-05	177	182	6	b1775e05c28883a15c56628028770bc59d3233fb
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP6 CELF4 ZGRF1 CSMD3 GHSR SCN3A	9.49e-05	179	182	6	7c8a2fa1326c73dc9e774df645b572864fd97133
Drug	APETx1, Anthopleura elegantissima	SCN2A SCN3A SCN8A SCN10A	5.60e-08	6	180	4	ctd:C475726
Drug	2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate	SCN2A SCN3A SCN8A SCN10A	2.58e-07	8	180	4	ctd:C489827
Drug	APETx2 protein, Anthopleura elegantissima	SCN2A SCN8A SCN10A	1.93e-06	4	180	3	ctd:C501880
Drug	Sodium	CACNA1E TRPC6 SCN2A SCN3A SCN5A SCN8A SCN10A	4.66e-06	84	180	7	ctd:D012964
Drug	Zonisamide	SCN1A SCN2A SCN3A SCN5A	8.30e-06	17	180	4	DB00909
Drug	fenpropathrin	SCN2A SCN3A SCN10A	9.55e-06	6	180	3	ctd:C044267
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	7.67e-12	10	173	6	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	7.67e-12	10	173	6	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	3.34e-11	12	173	6	DOID:0060170 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	SLC12A6 CACNA1E SLC25A4 KCNK18 KCNH1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN10A	3.62e-09	163	173	11	DOID:1826 (implicated_via_orthology)
Disease	Ventricular Fibrillation, Paroxysmal Familial, 1	DPP6 SCN5A	3.42e-05	2	173	2	C2751898
Disease	VENTRICULAR FIBRILLATION DURING MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO	DPP6 SCN5A	3.42e-05	2	173	2	C4017668
Disease	Paroxysmal familial ventricular fibrillation	DPP6 SCN5A	3.42e-05	2	173	2	cv:C0340493
Disease	Benign familial infantile epilepsy	SCN2A SCN8A	1.02e-04	3	173	2	cv:C5575231
Disease	polycystic kidney disease 2 (implicated_via_orthology)	PKD2L1 PKD2	1.02e-04	3	173	2	DOID:0110859 (implicated_via_orthology)
Disease	Global developmental delay	TRAF7 CACNA1E TRMT1 STT3B STAG2 KDM1A	1.38e-04	133	173	6	C0557874
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A HERC1	1.51e-04	18	173	3	HP_0002373
Disease	nevus count, cutaneous melanoma	DOCK8 RAPGEF1 TASOR2 SYNE2 HERC2	2.02e-04	91	173	5	EFO_0000389, EFO_0004632
Disease	Brugada ECG Pattern	SCN5A SCN10A	2.03e-04	4	173	2	C1721096
Disease	polycystic kidney disease (is_implicated_in)	ALG5 PKD2	2.03e-04	4	173	2	DOID:0080322 (is_implicated_in)
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	TMEM43 SYNE2	2.03e-04	4	173	2	cv:CN293514
Disease	Paroxysmal familial ventricular fibrillation	DPP6 SCN5A	2.03e-04	4	173	2	C0340493
Disease	Neurodevelopmental Disorders	DOCK8 KCNH1 SCN1A SCN2A SCN8A	2.24e-04	93	173	5	C1535926
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A SCN3A	2.81e-04	22	173	3	DOID:2030 (implicated_via_orthology)
Disease	Intellectual Disability	CACNA1E SETD1A DOCK8 TRMT1 STT3B SCN1A SCN3A SCN8A STAG2 TRAPPC6A	3.26e-04	447	173	10	C3714756
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	TMEM43 SYNE2	3.38e-04	5	173	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	TMEM43 SYNE2	3.38e-04	5	173	2	C0410190
Disease	Epilepsy	SETD1A KCNH1 SCN1A SCN2A SCN8A	4.67e-04	109	173	5	C0014544
Disease	Emery-Dreifuss muscular dystrophy	TMEM43 SYNE2	5.05e-04	6	173	2	cv:C0410189
Disease	contactin-1 measurement	MUC19 AXIN1	5.05e-04	6	173	2	EFO_0020286
Disease	Muscular Dystrophy, Emery-Dreifuss	TMEM43 SYNE2	5.05e-04	6	173	2	C0410189
Disease	Familial benign neonatal epilepsy	SCN2A SCN8A	5.05e-04	6	173	2	C0220669
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	7.04e-04	7	173	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	7.04e-04	7	173	2	C0751057
Disease	electrocardiography, PR interval	SCN5A SCN10A	7.04e-04	7	173	2	EFO_0004327, EFO_0004462
Disease	anxiety, vitamin D measurement	DPP6 DOCK8	7.04e-04	7	173	2	EFO_0004631, EFO_0005230
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	TMEM43 SYNE2	7.04e-04	7	173	2	C0751337
Disease	cutaneous melanoma	RAPGEF1 TASOR2 ADAMTS12 SYNE2 HERC2	7.51e-04	121	173	5	EFO_0000389
Disease	hemangiopericytoma (is_marker_for)	EPHB4 KDR	1.20e-03	9	173	2	DOID:264 (is_marker_for)
Disease	Focal Segmental Glomerulosclerosis, Not Otherwise Specified	TRPC6 INF2	1.20e-03	9	173	2	C4049702
Disease	Febrile Convulsions	SCN1A SCN2A	1.20e-03	9	173	2	C0009952
Disease	supraventricular ectopy	SCN5A SCN10A	1.20e-03	9	173	2	EFO_0009277
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	1.20e-03	9	173	2	C3502809
Disease	Primary ciliary dyskinesia	DNAAF11 DNAH5 HYDIN	1.23e-03	36	173	3	cv:C0008780
Disease	Epilepsy, Cryptogenic	KCNH1 SCN1A SCN2A SCN8A	1.40e-03	82	173	4	C0086237
Disease	Awakening Epilepsy	KCNH1 SCN1A SCN2A SCN8A	1.40e-03	82	173	4	C0751111
Disease	Aura	KCNH1 SCN1A SCN2A SCN8A	1.40e-03	82	173	4	C0236018
Disease	cataract	CASP7 PKD2L1 GMPS RIC8A HERC2	1.49e-03	141	173	5	MONDO_0005129
Disease	response to trastuzumab, methylcobalamin deficiency type cblE, left ventricular diastolic function measurement	TRPC6 LDB2	1.49e-03	10	173	2	EFO_0008204, EFO_0008347, MONDO_0009354
Disease	Inherited focal segmental glomerulosclerosis	TRPC6 INF2	1.49e-03	10	173	2	cv:CN327126
Disease	PRADER-WILLI SYNDROME	MAGEL2 HERC2	1.49e-03	10	173	2	176270
Disease	Prader-Willi syndrome	MAGEL2 HERC2	1.49e-03	10	173	2	cv:C0032897
Disease	Focal segmental glomerulosclerosis	TRPC6 INF2	1.49e-03	10	173	2	cv:C0017668
Disease	atrial fibrillation	SLC27A6 TAB2 ITPR2 SYNE2 SCN5A SCN10A HERC1 CDC27	1.62e-03	371	173	8	EFO_0000275
Disease	Hereditary Nephrotic Syndromes, Autosomal Dominant	TRPC6 INF2	1.82e-03	11	173	2	cv:CN043612
Disease	hepatocellular carcinoma (is_marker_for)	TRAF7 CENPA SRC AXIN1 KCNH1 KDR KDM1A	2.07e-03	301	173	7	DOID:684 (is_marker_for)
Disease	Royer Syndrome	MAGEL2 HERC2	2.17e-03	12	173	2	C0265222
Disease	Paroxysmal atrial fibrillation	SLC27A6 SYNE2 SCN5A SCN10A HERC1	2.31e-03	156	173	5	C0235480
Disease	familial atrial fibrillation	SLC27A6 SYNE2 SCN5A SCN10A HERC1	2.31e-03	156	173	5	C3468561
Disease	Persistent atrial fibrillation	SLC27A6 SYNE2 SCN5A SCN10A HERC1	2.31e-03	156	173	5	C2585653
Disease	hair color	EPHB4 FZD1 ADAMTS12 KIRREL3 KCNH1 SYNE2 HERC2	2.48e-03	311	173	7	EFO_0003924
Disease	obsolete_red blood cell distribution width	KLHL24 CFAP251 SLC27A6 DOCK8 TRMT1 PKD2L1 TF AXIN1 TRIM10 CAPN11 SLC19A1 SYNE2 HFM1 HERC1 MYO16 HEATR3 RAD9A	2.49e-03	1347	173	17	EFO_0005192
Disease	Familial idiopathic steroid-resistant nephrotic syndrome	TRPC6 INF2	2.55e-03	13	173	2	cv:C4273714
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	2.55e-03	13	173	2	C0751122
Disease	Brugada Syndrome 1	SCN5A SCN10A	2.55e-03	13	173	2	C4551804
Disease	Prader-Willi Syndrome	MAGEL2 HERC2	2.55e-03	13	173	2	C0032897
Disease	Atrial Fibrillation	SLC27A6 SYNE2 SCN5A SCN10A HERC1	2.58e-03	160	173	5	C0004238
Disease	Primary Ciliary Dyskinesia	DNAAF11 DNAH5 HYDIN	2.66e-03	47	173	3	C4551720
Disease	sciatic neuropathy (biomarker_via_orthology)	RANGAP1 NMNAT1 CASP7 ABCC8	2.79e-03	99	173	4	DOID:11446 (biomarker_via_orthology)
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	PKD2L1 PKD2	2.97e-03	14	173	2	DOID:898 (implicated_via_orthology)
Disease	T wave morphology measurement	SCN5A SCN10A	2.97e-03	14	173	2	EFO_0008398
Disease	smoking cessation	CACNA1E DPP6 RANGAP1 CELF4 GRID2 CSMD3 SCN2A	3.17e-03	325	173	7	EFO_0004319
Disease	MMR-related febrile seizures	SCN1A SCN2A	3.41e-03	15	173	2	EFO_0006519
Disease	P wave duration	SCN5A SCN10A	3.41e-03	15	173	2	EFO_0005094
Disease	Dupuytren Contracture	EIF3E TAB2 ATP9A KDR	3.81e-03	108	173	4	EFO_0004229
Disease	Romano-Ward Syndrome	SCN5A SCN10A	3.89e-03	16	173	2	C0035828
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	3.89e-03	16	173	2	C0393706
Disease	Ciliopathies	CCDC28B PKD2 CPLANE1 DNAH5	4.07e-03	110	173	4	C4277690
Disease	alcohol dependence measurement	C6orf118 ABCC8 MYO16	4.16e-03	55	173	3	EFO_0007835
Disease	QT interval	DPP6 SLC27A6 LDB2 ITPR2 C6orf118 ABCC8 SCN5A SCN10A IPO11	4.42e-03	534	173	9	EFO_0004682
Disease	coffee consumption measurement	MMS22L EIF3E GRID2 PKD2 HYDIN	4.47e-03	182	173	5	EFO_0006781
Disease	neuroblastoma	TDRD15 ASAP2 KRT71 DNAH5	4.91e-03	116	173	4	EFO_0000621
Disease	skin sensitivity to sun	ADAMTS12 HERC2	5.47e-03	19	173	2	EFO_0004795
Disease	Brugada syndrome	SCN5A SCN10A	5.47e-03	19	173	2	MONDO_0015263

Protein segments in the cluster

Peptide	Gene	Start	Entry
RDGIVFVLKCLDFSL	VANGL1	476	Q8TAA9
GQKARVVFAELACRE	ABCF1	746	Q8NE71
EEICESLRGDIFQKF	GRK3	151	P35626
LRFECQFGFELIGEK	CSMD3	686	Q7Z407
FSLECVLKVIAFGFL	CACNA1E	1521	Q15878
IRDTQCGFKLFTREA	ALG5	231	Q9Y673
VEELAFKCTENARFL	C4orf46	81	Q504U0
REALECSLKFVGFIV	ATP13A1	706	Q9HD20
FDCVRLLLTFGAKAN	ASB16	156	Q96NS5
CIAFELLGKNTFEFL	CLK3	381	P49761
LSVKFGVLFRDDKCA	ABRACL	26	Q9P1F3
GVLFRDDKCANLFEA	ABRACL	31	Q9P1F3
EGFLRFQEEVLAKCS	ASCC1	176	Q8N9N2
LLKFVVSSLQGEDCR	COMMD5	51	Q9GZQ3
RFLKNCEEVGLFNEL	ATF7	56	P17544
FEELRAACLRKGELF	CAPN11	66	Q9UMQ6
VDVDKGLTLACFVFL	CTXND1	11	A0A1B0GTU2
TCRSQTKLIFEIGFL	ATP2C2	856	O75185
VAVLLTRKDICAGFN	ADAMTS12	341	P58397
DFRLCVKLTREIFAQ	CHDH	461	Q8NE62
LLFNKREFFICIAQG	ATP8B2	966	P98198
DCTLKGDLFVLRNFI	CFAP251	566	Q8TBY9
CKAIIDQFGQRIISE	CHM	416	P24386
KTLRQVEVINFGDCL	RANGAP1	261	P46060
VFLCFQKVAAEILGI	RAB28	166	P51157
DINFLGFTKRVELIC	PATE2	86	Q6UY27
IKLLSFGERQCVFIS	PAAT	146	Q9H8K7
LKRDLVVAAQNFFCA	RUBCNL	421	Q9H714
KDGSCLFRAVAEQVL	OTUD4	41	Q01804
ALRENEAGSCFIFLV	RAB36	221	O95755
EGVAITFCLKEFRGL	RAD9A	211	Q99638
QKEVDFCISLLRERF	INTS3	231	Q68E01
SCLQELFKAHFRGEV	INTS3	621	Q68E01
FQCEFVKLRIDLLQA	INTS7	616	Q9NVH2
LCNKIVFLVSFVGNR	ITPR2	2316	Q14571
FVERKIISFDECIAQ	OR4M2B	86	A0A0X1KG70
FKLDEVAAVAVLLCG	SLC10A4	161	Q96EP9
CFDGIEIDILFARLA	PAPOLB	161	Q9NRJ5
KILDFGLARTACTNF	MAPK9	166	P45984
IDVLVVKQVDGSFRC	LPIN3	31	Q9BQK8
LKFAQFLLTACGTEV	IL17RA	396	Q96F46
GEFEKFLEELCRILN	KCNK18	56	Q7Z418
DFFDILVKCQGSRLD	GPSM2	596	P81274
EGFLINEDLKTCSRV	MATN2	471	O00339
CVREDLIFNFLFKLG	MAGEL2	1126	Q9UJ55
FDICTSRKLLEGNFA	RNGTT	416	O60942
FRQDVTKCLFLGIIS	LETMD1	131	Q6P1Q0
NLVCKVSDFGLSRFL	EPHB4	751	P54760
VNLTVRFCILGKESF	HACD3	166	Q9P035
TAVDGVFIRSLKVNC	ITIH1	46	P19827
DSRFKHVVCILEAFG	MYO16	526	Q9Y6X6
LGVTQIACAEKRFLI	HERC2	451	O95714
DLDVVKVRCGSQFSI	HERC2	656	O95714
QFDLDVFISRALKLC	MAPK4	536	P31152
LDIGVLAEKFSCAFR	MMS22L	586	Q6ZRQ5
CEAVKTRDIFGLLQA	ASAP2	551	O43150
CFGNKAAVLSVFVRL	ATRN	1361	O75882
KDFLVGQDRCADVTL	MESD	171	Q14696
GIFERLKQFLECSRS	IPO11	241	Q9UI26
TAGKIFQCFLSAREV	HERC1	1381	Q15751
KVCTEGRLILEFTFD	LDB2	136	O43679
ILKTAEGFLFVVGCE	ARNTL2	186	Q8WYA1
ACFIDIVVENLAGLK	CLCN7	141	P51798
FKKGDVRFLICTDVA	DDX1	561	Q92499
LDIKSFAGVFCILAA	GRID2	826	O43424
IAFDDFIQGCIVLQR	PDCD6	146	O75340
FVERKIISFGGCIAQ	OR4M1	86	Q8NGD0
FVERKIISFDGCIAQ	OR4M2	86	Q8NGB6
DGLTCSRKIIVAFQD	MUC19	1326	Q7Z5P9
LIKCGIRLFFEINVV	PDE6C	521	P51160
KVAATLQTLFLVDCG	PRAMEF18	346	Q5VWM3
IRNEQDKVVLFLCTF	KCNH1	116	O95259
AFCLTQLSKGIFREQ	LPXN	356	O60711
LVQAVRAAGKCDAVF	NRN1	21	Q9NPD7
IRICDFGFAKQLRGE	RPS6KA6	561	Q9UK32
IQKFLDIARQTECFF	MED28	81	Q9H204
FDLEVNCLTKILFGA	ATP9A	296	O75110
LEACQRERAFSVKFE	OAS1	106	P00973
EQLLCRIFGEDFIAT	HSPA12B	361	Q96MM6
CVIDALLADIRKGFQ	INF2	971	Q27J81
RNILKTFEECVLGLA	PRPF39	441	Q86UA1
TLIAGCKEFLDIQLR	HFM1	811	A2PYH4
LGKAFELVFVSLRFC	NTN3	111	O00634
AGFLLEDRVVCNDKF	FZD1	371	Q9UP38
RAVSIFNKEGCLEIV	HEATR3	176	Q7Z4Q2
NLSFETKELDFGCIL	HYDIN	1166	Q4G0P3
LTTLLGVLFCFNKRD	IL6ST	631	P40189
TCSLFRGLQKEEVVL	GMPS	136	P49915
FGNLNKVVLCFDRVF	KDM1A	656	O60341
FQISVLRDACAKFLE	KLHL24	146	Q6TFL4
LGQVIKTEEFCEIFR	CAMKV	26	Q8NCB2
CFATLRALIAKFGDL	DOCK8	1481	Q8NF50
SVSIGVAFQLFCKRD	CPLANE1	1031	Q9H799
KCFEGIAKLEFTDNL	DNAH3	1201	Q8TD57
FGDLLCKLFQFVSES	GHSR	111	Q92847
AREICVKFTRGVDFN	CENPA	71	P49450
RFTGQALEKFVLIDC	FAM83C	246	Q9BQN1
KTRFSLALECGNIEI	COPA	646	P53621
LFRTFLKQEGCADLL	AXIN1	101	O15169
FQKRLTFGIQRELCD	POLQ	781	O75417
LFEVLTDGARLKKCF	DEFB128	11	Q7Z7B8
RLHVFGKVFEDICNS	C6orf118	266	Q5T5N4
FQRFAKIFIGCLAAV	DPY19L4	46	Q7Z388
KLRECESVLVNDFFL	EIF3E	311	P60228
RLGCFNLFSKILDEV	DENND2C	596	Q68D51
ALFKCFRSLGFDVIV	CASP7	96	P55210
GCEELAKLDLTVNFI	DNAAF11	86	Q86X45
LRFIQVFLQSICDGE	GLTP	101	Q9NZD2
GVVALFKVCRQDSFR	INSC	281	Q1MX18
LVKLCQEASSGEVFL	INSC	376	Q1MX18
VCFFLFSQELGLQKR	KIRREL3	11	Q8IZU9
LEACADNKDFAILRF	CACTIN	696	Q8WUQ7
FVNGVLFCKVRLLDG	FAM102A	26	Q5T9C2
NFFVECFRIQDKLLT	DPP6	841	P42658
RLQAFGKECSFEQLE	CCDC28B	106	Q9BUN5
RKFCDQFLGQVTLDA	CAPN6	586	Q9Y6Q1
FCQLVVAAKLREGIS	SLC12A6	826	Q9UHW9
FVLTEELDKALACFR	CDC27	611	P30260
DLFLCERLDVKAVFQ	IPO13	806	O94829
ERLDVKAVFQCAVLA	IPO13	811	O94829
VFREDLCTKTENLLG	PSME1	16	Q06323
TLSDIKLLQFFGVCF	FPGT	496	O14772
RVKLASCGFIDNVVL	DNAH5	2116	Q8TE73
SCGFIDNVVLARKFF	DNAH5	2121	Q8TE73
EKIISFVACGIQIFL	OR2T11	86	Q8NH01
CTRVKEFIFLGLTQN	OR4D10	6	Q8NGI6
LQFDQREFVCLKFLV	NR5A2	441	O00482
LVCKVADFGLARLIE	SRC	401	P12931
CAVITEFARIQLGAK	TRMT1	86	Q9NXH9
RDLVNIGLKAFAFCV	TMEM43	341	Q9BTV4
RGIDFFEFLCQLILK	TIGAR	131	Q9NQ88
FLARLDTSFQKCGEI	SYNE2	531	Q8WXH0
IDCLTKEIDLFQARG	TAB2	606	Q9NYJ8
QAIKCFLSDLRDVDI	TDRD15	1076	B5MCY1
KVAATLQTLFLVDCG	PRAMEF19	346	Q5SWL8
AKINLLFVAIFTGEC	SCN5A	1561	Q14524
LFVAIFTGECIVKLA	SCN5A	1566	Q14524
VFCKGLSRTLLAFFE	SMIM10L1	26	P0DMW3
EKFRDCRGLQFLLTT	SHPRH	1181	Q149N8
IVQFLLEKGCDRSIV	NUDT12	61	Q9BQG2
TFESLIKILARGFCL	SCN3A	166	Q9NY46
IKILARGFCLEDFTF	SCN3A	171	Q9NY46
LTIGADAVEAQCKRF	SGCZ	126	Q96LD1
FVIQVLDAFLCAVGL	SLCO1B7	491	G3V0H7
TDVKRVAAEFLFVLC	RIC8A	386	Q9NPQ8
TIIDATKCGNLARFI	SETD1A	1631	O15047
FKRSIVCLEDLQIGT	SRBD1	906	Q8N5C6
TFESLIKIIARGFCL	SCN1A	166	P35498
IKIIARGFCLEDFTF	SCN1A	171	P35498
GTLKDFQRSECQLFE	ABCC8	911	Q09428
QREFHGLGDCIIKIF	SLC25A4	151	P12235
LFEAFGNIEECTILR	CELF4	171	Q9BZC1
ENCSVLALELFKEIF	CIP2A	356	Q8TCG1
FTKILRVQEVCAGAL	CHST5	361	Q9GZS9
FRLCGTDEKILANVT	RNF213	1061	Q63HN8
TVCKRQDKEFFGLRD	RNF213	2941	Q63HN8
KCKILIFQTDFEDGI	RNF213	3371	Q63HN8
VEFGLCKQDGQLRVF	TPH1	316	P17752
FCEGKLSQAVITERL	ZFP28	191	Q8NHY6
SRCEKFLQKDIFEIG	ZNF565	121	Q8N9K5
GAAIIISVVCFARNK	VSIG1	246	Q86XK7
GNFCLFRSETKDLLF	TF	636	P02787
VQIFDDGRKFSCHIR	CD96	236	P40200
FLERCRQFGVIAKTQ	RLF	336	Q13129
KNTFFVLVRVVDELC	RAPGEF1	756	Q13905
FFKDALRDQGRIVCA	SPIDR	721	Q14159
FKSSFCEFIGVLVRQ	STAG2	171	Q8N3U4
FEALIKILARGFCLN	SCN10A	166	Q9Y5Y9
FCIKNINDERVFVAL	STT3B	431	Q8TCJ2
LSKELCALVFGVNTF	SLC19A1	391	P41440
LIKILARGFCLEDFT	SCN2A	171	Q99250
GITAACKLRFDRIFF	TDP2	306	O95551
TCRFEGLKEFLQQTD	TRAF7	281	Q6Q0C0
FESLVKIIARGFCID	SCN8A	171	Q9UQD0
IIDFRLFAKLNAFCV	VPS13C	1081	Q709C8
LKDRGFCVEVNTAFE	PRPF40B	566	Q6NWY9
EKNGSFCSRLIIVLD	TMEM168	531	Q9H0V1
LKQIREICSLFGEAS	USP9Y	571	O00507
ECIFTQFRIILGDIN	PKD2	631	Q13563
IFRAFTELFQVACAK	TTLL12	551	Q14166
KCIFTQFRIILGDFD	PKD2L1	511	Q9P0L9
TLAFREELDVLKFLC	TRAPPC6A	56	O75865
LNDCRIIFVDEVFKI	UHRF1	266	Q96T88
FDLLVAGEICRFSAL	TRIM10	221	Q9UDY6
SEGRELIKIFLLECN	USP24	2216	Q9UPU5
FQGAEKEIIILSCVR	ZGRF1	1996	Q86YA3
DGKTALEVCRAFLQE	ZCCHC4	251	Q9H5U6
RVKELFSSLGVECNV	TXNRD3	81	Q86VQ6
QLAIIKCLEDRGFFI	TASOR2	116	Q5VWN6
SVLGCAKVEAFFIIE	KDR	741	P35968
KDFVVGLLDLCRNTE	TRPC6	326	Q9Y210
REFLDRFGNIKVCEL	SLC27A6	346	Q9Y2P4
LSVAAFCLVRFQKER	VSIG2	256	Q96IQ7
FEAVEKVAVICRFLD	UNC79	1061	Q9P2D8
EIKFFRCLFEAEITQ	KRT71	261	Q3SY84
GISKTDLRAFVQFCI	NADSYN1	541	Q6IA69
VKLLCGADLLESFAV	NMNAT1	151	Q9HAN9