Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleosome binding

ARID1B SMARCC1 CHD4 SSRP1 ARID1A

1.33e-0598625GO:0031491
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

2.77e-05114625GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.15e-05124625GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

6.68e-05137625GO:0019783
GeneOntologyMolecularFunctionphosphatidic acid transfer activity

PRELID3A PRELID3B

1.97e-047622GO:1990050
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.24e-04192625GO:0008234
GeneOntologyBiologicalProcessprotein deubiquitination

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.16e-05125605GO:0016579
GeneOntologyBiologicalProcessnucleosome disassembly

SMARCC1 SSRP1 ARID1A

3.46e-0522603GO:0006337
GeneOntologyBiologicalProcessprotein-DNA complex disassembly

SMARCC1 SSRP1 ARID1A

4.53e-0524603GO:0032986
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

6.20e-05144605GO:0070646
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

ARID1B SMARCC1 ARID1A

8.10e-0529603GO:2000819
GeneOntologyCellularComponentnpBAF complex

ARID1B SMARCC1 ARID1A

8.00e-0614603GO:0071564
GeneOntologyCellularComponentbrahma complex

ARID1B SMARCC1 ARID1A

8.00e-0614603GO:0035060
GeneOntologyCellularComponentnBAF complex

ARID1B SMARCC1 ARID1A

1.23e-0516603GO:0071565
GeneOntologyCellularComponentSWI/SNF complex

ARID1B SMARCC1 ARID1A

8.64e-0530603GO:0016514
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

ARID1B SMARCC1 CHD4 ARID1A

1.67e-0496604GO:0070603
GeneOntologyCellularComponentexcitatory synapse

SEMA3A CHD4 FGFR2 BSN

2.54e-04107604GO:0060076
GeneOntologyCellularComponentbBAF complex

ARID1B ARID1A

3.59e-0410602GO:0140092
GeneOntologyCellularComponentATPase complex

ARID1B SMARCC1 CHD4 ARID1A

5.17e-04129604GO:1904949
GeneOntologyCellularComponentnuclear protein-containing complex

NCOA2 ARID1B SUGP1 SMARCC1 CHD4 SSRP1 ARID1A MIDEAS RBM47 CWC22 HNRNPH1

1.68e-0313776011GO:0140513
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

SEMA3A CHD4

2.15e-0324602GO:0098985
GeneOntologyCellularComponentasymmetric synapse

SEMA3A TANC2 CHD4 BSN HNRNPH1 HNRNPH2

2.42e-03477606GO:0032279
GeneOntologyCellularComponentchromatin

SOX3 NCOA2 TFEB ARID1B SMARCC1 TNKS1BP1 CHD4 PAX7 SSRP1 FOXA1 ARID1A

2.96e-0314806011GO:0000785
DomainHABP4_PAI-RBP1

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

1.34e-0916615PF04774
DomainHABP4_PAIRBP1-bd

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

1.34e-0916615IPR006861
DomainUSP_CS

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

2.41e-0666615IPR018200
DomainUSP_1

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.23e-0670615PS00972
DomainUCH

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.47e-0671615PF00443
DomainUSP_2

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.47e-0671615PS00973
DomainUSP_3

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.72e-0672615PS50235
DomainUSP_dom

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.72e-0672615IPR028889
DomainPeptidase_C19_UCH

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.72e-0672615IPR001394
DomainBAF250_C

ARID1B ARID1A

1.05e-052612IPR033388
DomainBAF250_C

ARID1B ARID1A

1.05e-052612PF12031
DomainBAF250/Osa

ARID1B ARID1A

1.05e-052612IPR021906
Domainzf-RNPHF

HNRNPH1 HNRNPH2

3.14e-053612PF08080
DomainZnf_CHHC

HNRNPH1 HNRNPH2

3.14e-053612IPR012996
DomainHMG_box_dom

SOX3 CHD4 SSRP1 TOX2

6.01e-0565614IPR009071
DomainPRELI_MSF1

PRELID3A PRELID3B

1.56e-046612PS50904
DomainPRELI

PRELID3A PRELID3B

1.56e-046612PF04707
DomainPRELI/MSF1_dom

PRELID3A PRELID3B

1.56e-046612IPR006797
DomainVHS

GGA2 HGS

3.72e-049612PF00790
DomainVHS

GGA2 HGS

3.72e-049612PS50179
DomainVHS

GGA2 HGS

3.72e-049612SM00288
DomainVHS_dom

GGA2 HGS

3.72e-049612IPR002014
DomainHMG_box

SOX3 SSRP1 TOX2

6.91e-0453613PF00505
DomainHMG_BOX_2

SOX3 SSRP1 TOX2

7.30e-0454613PS50118
DomainHMG

SOX3 SSRP1 TOX2

7.30e-0454613SM00398
Domain-

SOX3 SSRP1 TOX2

7.71e-04556131.10.30.10
Domain-

ARID1B ARID1A

1.07e-03156121.10.150.60
DomainBRIGHT

ARID1B ARID1A

1.07e-0315612SM00501
DomainARID_dom

ARID1B ARID1A

1.07e-0315612IPR001606
DomainARID

ARID1B ARID1A

1.07e-0315612PS51011
DomainARID

ARID1B ARID1A

1.07e-0315612PF01388
Domain-

GGA2 HGS

3.24e-03266121.25.40.90
DomainSANT_dom

SMARCC1 MIDEAS

3.24e-0326612IPR017884
DomainSANT

SMARCC1 MIDEAS

3.76e-0328612PS51293
DomainENTH_VHS

GGA2 HGS

4.02e-0329612IPR008942
DomainRRM_1

ELAVL4 RBM47 HNRNPH1 HNRNPH2

4.75e-03208614PF00076
DomainChromo/shadow_dom

SMARCC1 CHD4

5.19e-0333612IPR000953
DomainCHROMO

SMARCC1 CHD4

5.19e-0333612SM00298
DomainRRM

ELAVL4 RBM47 HNRNPH1 HNRNPH2

5.52e-03217614SM00360
DomainMyb_DNA-binding

SMARCC1 MIDEAS

5.83e-0335612PF00249
DomainRRM_dom

ELAVL4 RBM47 HNRNPH1 HNRNPH2

6.45e-03227614IPR000504
PathwayREACTOME_RAS_PROCESSING

USP17L21 USP17L12 USP17L20 USP17L5

1.59e-0545484MM15671
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L12 USP17L20 HGS USP17L24 USP17L5

9.82e-05221486M27578
PathwayWP_KLEEFSTRA_SYNDROME

ARID1B SMARCC1 ARID1A

1.27e-0429483M48076
PathwayWP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1

ARID1B SMARCC1 ARID1A

1.56e-0431483M39522
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

ARID1B SMARCC1 ARID1A

2.25e-0435483M47969
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

ARID1B SMARCC1 ARID1A

2.65e-0437483M27797
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS

ARID1B SMARCC1 CHD4 ARID1A

3.25e-0497484M48262
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

ARID1B SMARCC1 ARID1A

3.87e-0442483M48237
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L12 USP17L20 HGS USP17L5

4.63e-04191485MM15289
PathwayWP_THERMOGENESIS

ARID1B LIPE SMARCC1 ARID1A

4.89e-04108484M39746
PathwayBIOCARTA_HSWI_SNF_PATHWAY

SMARCC1 ARID1A

5.02e-0410482MM1532
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L12 USP17L20 HGS USP17L24 USP17L5

5.02e-04299486M27574
PathwayWP_ANDROGEN_RECEPTOR_NETWORK_IN_PROSTATE_CANCER

ARID1B SMARCC1 FOXA1 ARID1A

5.24e-04110484M48043
PathwayBIOCARTA_HSWI_SNF_PATHWAY

SMARCC1 ARID1A

7.33e-0412482M22006
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

TFEB ARID1B SMARCC1 ARID1A

1.19e-03137484M48232
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

ARID1B SMARCC1 CHD4 ARID1A

1.36e-03142484M48257
PathwayWP_MAP3K1_ROLE_IN_PROMOTING_AND_BLOCKING_GONADAL_DETERMINATION

FGFR2 MAP3K4

1.49e-0317482M39907
PathwayWP_INHIBITION_OF_EXOSOME_BIOGENESIS_AND_SECRETION_BY_MANUMYCIN_A_IN_CRPC_CELLS

HGS HNRNPH1

1.68e-0318482M39737
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

NCOA2 ZNF462 ARID1B SMARCC1 CHD4 SSRP1 FOXA1 ARID1A MIDEAS HNRNPH2

6.74e-12220621035785414
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 ARID1B SUGP1 SMARCC1 SSBP2 CHD4 FOXA1 ARID1A MIDEAS PRRC2B

4.72e-11268621033640491
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.49e-093362520228807
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462520403174
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462517109758
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462520388806
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462514699124
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462520715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-09346259806828
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462520368735
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462515780755
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462519188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462511941478
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462510936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.08e-093462521448158
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.76e-093562516611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

4.76e-093562521239494
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

5.52e-093662520147298
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

6.37e-093762520228808
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

ARID1B SMARCC1 CHD4 FOXA1 ARID1A

9.58e-094062534585037
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 NCOA2 ZNF462 MAGI1 GPRASP1 CELSR2 ATXN2 FAM120C SMARCC1 ELAVL4 CHD4 BSN PRRC2B

1.23e-08963621328671696
Pubmed

Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.

ARID1B SMARCC1 ARID1A

2.16e-08462315170388
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L21 USP17L12 USP17L20 USP17L5

5.35e-08216248622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L21 USP17L12 USP17L20 USP17L5

5.35e-082162414583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L21 USP17L12 USP17L20 USP17L5

5.35e-082162411468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L21 USP17L12 USP17L20 USP17L5

5.35e-08216248756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L21 USP17L12 USP17L20 USP17L5

5.35e-082162412447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L21 USP17L12 USP17L20 USP17L5

5.35e-082162418980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L21 USP17L12 USP17L20 USP17L5

6.54e-08226249154835
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ARID1B SMARCC1 YTHDC2 CHD4 SSRP1 ARID1A HNRNPH1 HNRNPH2 MAP3K4

8.58e-0844062934244565
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L21 USP17L12 USP17L20 USP17L5

9.47e-08246248995226
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

ARID1B SMARCC1 ARID1A

1.07e-07662316230384
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L21 USP17L12 USP17L20 USP17L5

1.13e-072562421115691
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NPC1 NCOA2 ARID1B ATXN2 SMARCC1 ARID1A MIDEAS RBM47 PRRC2B

1.18e-0745762932344865
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L21 USP17L12 USP17L20 USP17L5

1.33e-072662435816173
Pubmed

Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.

ARID1B SMARCC1 ARID1A

1.88e-07762323540691
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 ZNF462 ARID1B SMARCC1 SSBP2 ARID1A MIDEAS PRRC2B

2.09e-0735162838297188
Pubmed

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

ARID1B SMARCC1 CHD4 ARID1A

2.10e-072962436800290
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L21 USP17L12 USP17L20 USP17L5

2.10e-072962432527007
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

SUGP1 SMARCC1 CHD4 APOBEC3C SSRP1 CWC22 SPTY2D1

3.29e-0725162731076518
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ZNF462 ARID1B SUGP1 SMARCC1 TNKS1BP1 SSBP2 CHD4 SSRP1 ARID1A CWC22 HNRNPH1 HNRNPH2

3.98e-071082621238697112
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA2 ARID1B SMARCC1 ARID1A MIDEAS

3.98e-078362528794006
Pubmed

Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.

ARID1B SMARCC1 ARID1A

4.50e-07962320086098
Pubmed

The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.

ARID1B SMARCC1 ARID1A

4.50e-07962337805104
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

ARID1B SMARCC1 CHD4 ARID1A

5.78e-073762424335282
Pubmed

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

ARID1B SMARCC1 ARID1A

6.42e-071062312665591
Pubmed

Human transcription factor protein interaction networks.

NCOA2 ZNF462 ARID1B ATXN2 HGS SUGP1 SMARCC1 SSBP2 PAX7 FOXA1 ARID1A MIDEAS PRRC2B

1.14e-061429621335140242
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

ZNF462 SMARCC1 CHD4 SSRP1 CWC22

1.17e-0610362532744500
Pubmed

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

ARID1B SMARCC1 ARID1A

1.17e-061262311734557
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

ARID1B ATXN2 SMARCC1 YTHDC2 SSRP1 ARID1A MIDEAS HNRNPH1 PRRC2B

1.40e-0661562931048545
Pubmed

Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1.

ARID1B SMARCC1 ARID1A

1.52e-061362317340523
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

ATXN2 FAM120C SUGP1 YTHDC2 APOBEC3C SSRP1 RBM47 HNRNPH1 HNRNPH2 PRRC2B

1.55e-06807621022681889
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

SMARCC1 CHD4 SSRP1 ARID1A TOX2 PRRC2B

1.72e-0620362622083510
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TANC2 NCOA2 ARID1B DNAH12 SUGP1 SMARCC1 BSN ARID1A PRRC2B

1.90e-0663862931182584
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L21 USP17L12 USP17L20 USP17L5

1.98e-065062431806660
Pubmed

Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.

ARID1B SMARCC1 ARID1A

2.42e-061562317255939
Pubmed

Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

ARID1B SMARCC1 ARID1A

2.42e-061562323785148
Pubmed

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

ARID1B SMARCC1 ARID1A

2.42e-061562311263494
Pubmed

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.

ARID1B SMARCC1 ARID1A

2.42e-061562311175787
Pubmed

Regulation of dendritic development by neuron-specific chromatin remodeling complexes.

ARID1B SMARCC1 ARID1A

2.42e-061562317920018
Pubmed

Hrs regulates the endocytic sorting of the fibroblast growth factor receptor 2b.

HGS FGFR2

3.13e-06262219362549
Pubmed

Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.

ARID1B ARID1A

3.13e-06262234386776
Pubmed

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

ARID1B ARID1A

3.13e-06262223202128
Pubmed

ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.

ARID1B ARID1A

3.13e-06262233890484
Pubmed

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

ARID1B ARID1A

3.13e-06262224562383
Pubmed

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.

ARID1B ARID1A

3.13e-06262237611161
Pubmed

Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.

ARID1B ARID1A

3.13e-06262232791957
Pubmed

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.

ARID1B ARID1A

3.13e-06262229890703
Pubmed

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

ARID1B ARID1A

3.13e-06262224788099
Pubmed

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

ARID1B ARID1A

3.13e-06262228967863
Pubmed

Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.

ARID1B ARID1A

3.13e-06262233052929
Pubmed

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

ARID1B ARID1A

3.13e-06262227562491
Pubmed

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

ARID1B SMARCC1 ARID1A

3.60e-061762312368262
Pubmed

The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.

ARID1B SMARCC1 ARID1A

3.60e-061762311078522
Pubmed

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

SMARCC1 CHD4 ARID1A

4.32e-061862328068325
Pubmed

BAF complexes facilitate decatenation of DNA by topoisomerase IIα.

ARID1B SMARCC1 ARID1A

4.32e-061862323698369
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

ADSL ATXN2 SUGP1 SMARCC1 CHD4 ARID1A MIDEAS

4.34e-0637062722922362
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

TFEB SMARCC1 CHD4 ARID1A HNRNPH1

4.43e-0613562531077711
Pubmed

Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.

ARID1B SMARCC1 ARID1A

5.12e-061962316932743
Pubmed

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

ARID1B SMARCC1 ARID1A

5.12e-061962312110891
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

SUGP1 ELAVL4 APOBEC3C SSRP1 RBM47 CWC22 HNRNPH1 HNRNPH2 PRRC2B

5.24e-0672362934133714
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 ARID1B SMARCC1 TNKS1BP1 SSRP1 ARID1A MIDEAS PRRC2B

5.86e-0654962838280479
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

ZNF462 CHD4 ARID1A MIDEAS HNRNPH2

6.50e-0614662523892456
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ARID1B ATXN2 SUGP1 SMARCC1 CHD4 SSRP1 ARID1A MIDEAS CWC22 HNRNPH1

6.80e-06954621036373674
Pubmed

Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.

TNKS1BP1 HNRNPH1 HNRNPH2

8.11e-062262318377426
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

ZNF462 SMARCC1 CHD4 ARID1A SPTY2D1 HNRNPH1 HNRNPH2

8.60e-0641162735182466
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

SMARCC1 ELAVL4 CHD4 SSRP1 HNRNPH1 HNRNPH2

9.03e-0627162632433965
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

HGS SMARCC1 YTHDC2 CHD4 APOBEC3C SSRP1 HNRNPH1 HNRNPH2

9.07e-0658362829844126
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

ARID1B SMARCC1 CHD4 SSRP1 ARID1A

9.25e-0615762530186101
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

ARID1B SMARCC1 ARID1A

9.31e-062362330962207
Pubmed

Diversity and specialization of mammalian SWI/SNF complexes.

ARID1B SMARCC1 ARID1A

9.31e-06236238804307
Pubmed

Loss of ARID1B and SMARCB1 expression are specific for the diagnosis of dedifferentiated/undifferentiated carcinoma in tumours of the upper gynaecological tract and cervix.

ARID1B ARID1A

9.37e-06362233432679
Pubmed

Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.

ARID1B ARID1A

9.37e-06362221647563
Pubmed

TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.

ARID1B ARID1A

9.37e-06362234044070
Pubmed

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes.

ARID1B ARID1A

9.37e-06362226716708
Pubmed

Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation.

SMARCC1 ARID1A

9.37e-06362236931659
Pubmed

hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.

HNRNPH1 HNRNPH2

9.37e-06362210456323
Pubmed

Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

ARID1B ARID1A

9.37e-06362222426308
Pubmed

Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer.

ARID1B ARID1A

9.37e-06362224382590
Pubmed

Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.

HNRNPH1 HNRNPH2

9.37e-06362214980514
InteractionEGR2 interactions

NCOA2 ZNF462 ARID1B SMARCC1 SSBP2 ARID1A MIDEAS PRRC2B

3.50e-08171598int:EGR2
InteractionCRX interactions

SOX3 NCOA2 ZNF462 ARID1B HGS SMARCC1 ARID1A MIDEAS PRRC2B

5.05e-08254599int:CRX
InteractionAR interactions

NCOA2 ZNF462 ARID1B SUGP1 SMARCC1 SSBP2 CHD4 ITPRID2 SSRP1 FOXA1 ARID1A MIDEAS HNRNPH1 HNRNPH2 PRRC2B

1.13e-079925915int:AR
InteractionMYCN interactions

ARID1B ATXN2 FAM120C SUGP1 SMARCC1 ELAVL4 YTHDC2 CHD4 APOBEC3C SSRP1 ARID1A MIDEAS CWC22 SPTY2D1 HNRNPH1 HNRNPH2 PRRC2B

2.38e-0713735917int:MYCN
InteractionSS18L1 interactions

ARID1B HGS SMARCC1 PAX7 ARID1A HNRNPH1

4.14e-0798596int:SS18L1
InteractionTLX1 interactions

NCOA2 ZNF462 ARID1B SMARCC1 SSBP2 ARID1A MIDEAS

7.70e-07175597int:TLX1
InteractionESRRB interactions

NCOA2 ZNF462 TFEB SMARCC1 CHD4 ARID1A HNRNPH1 HNRNPH2

9.17e-07262598int:ESRRB
InteractionALG13 interactions

NCOA2 ARID1B ATXN2 FAM120C ARID1A RBM47 PRRC2B

1.04e-06183597int:ALG13
InteractionTBXT interactions

NCOA2 ARID1B SMARCC1 SSBP2 ARID1A MIDEAS

1.12e-06116596int:TBXT
InteractionHNF1B interactions

NCOA2 ARID1B SMARCC1 PAX7 ARID1A MIDEAS PRRC2B

1.34e-06190597int:HNF1B
InteractionGCM1 interactions

ARID1B SMARCC1 ARID1A MIDEAS PRRC2B

1.64e-0668595int:GCM1
InteractionSNRNP40 interactions

NPC1 ZNF462 ARID1B SUGP1 SMARCC1 SSRP1 ARID1A MIDEAS CWC22 SPTY2D1 HNRNPH1

2.03e-066375911int:SNRNP40
InteractionSOX2 interactions

SOX3 NCOA2 ZNF462 TFEB COL8A1 ARID1B SMARCC1 YTHDC2 CHD4 ITPRID2 SSRP1 ARID1A MIDEAS HNRNPH1 HNRNPH2 PRRC2B

2.09e-0614225916int:SOX2
InteractionRBMS1 interactions

ATXN2 FAM120C SUGP1 FOXA1 RBM47 HNRNPH1 PRRC2B

2.36e-06207597int:RBMS1
InteractionHSFY1 interactions

HGS CHD4 RBM47 TOX2

2.88e-0634594int:HSFY1
InteractionSNIP1 interactions

TANC2 COL8A1 ARID1B CHD4 SSRP1 ARID1A CWC22 SPTY2D1 HNRNPH1

3.21e-06417599int:SNIP1
InteractionPHF10 interactions

ARID1B CELSR2 SMARCC1 SSRP1 ARID1A HNRNPH1

3.22e-06139596int:PHF10
InteractionERG interactions

NCOA2 ARID1B SMARCC1 ARID1A MIDEAS HNRNPH1 PRRC2B

3.87e-06223597int:ERG
InteractionNFIX interactions

ARID1B SMARCC1 PAX7 FOXA1 ARID1A MIDEAS HNRNPH1

4.35e-06227597int:NFIX
InteractionPOU5F1 interactions

ZNF462 TFEB ARID1B SUGP1 SMARCC1 CHD4 SSRP1 ARID1A TOX2 PRRC2B

6.76e-065845910int:POU5F1
InteractionSMARCA2 interactions

TANC2 ARID1B SMARCC1 YTHDC2 CHD4 ITPRID2 PAX7 ARID1A

7.20e-06346598int:SMARCA2
InteractionTFCP2L1 interactions

ZNF462 SMARCC1 CHD4 ARID1A MIDEAS

1.05e-0599595int:TFCP2L1
InteractionPAX6 interactions

SOX3 ZNF462 ARID1B HGS SMARCC1 ARID1A MIDEAS PRRC2B

1.08e-05366598int:PAX6
InteractionSIRT6 interactions

ARID1B CELSR2 SMARCC1 YTHDC2 CHD4 SSRP1 ARID1A HNRNPH1 HNRNPH2 MAP3K4

1.27e-056285910int:SIRT6
InteractionTLE3 interactions

NCOA2 ARID1B TNKS1BP1 PAX7 FOXA1 ARID1A MIDEAS HNRNPH1

1.32e-05376598int:TLE3
InteractionSMARCD3 interactions

ARID1B SMARCC1 PAX7 ARID1A HNRNPH1

1.53e-05107595int:SMARCD3
InteractionGATA3 interactions

ARID1B SMARCC1 FOXA1 ARID1A MIDEAS PRRC2B

1.76e-05187596int:GATA3
InteractionNFIA interactions

NCOA2 ARID1B PAX7 FOXA1 ARID1A MIDEAS

1.82e-05188596int:NFIA
InteractionPAX8 interactions

NCOA2 ARID1B ARID1A MIDEAS PRRC2B

1.83e-05111595int:PAX8
InteractionSMAP2 interactions

GGA2 ATXN2 HGS FGFR2 RBM47 PRRC2B

1.87e-05189596int:SMAP2
InteractionMYOD1 interactions

NCOA2 ARID1B SMARCC1 PAX7 ARID1A MIDEAS

2.17e-05194596int:MYOD1
InteractionTPRX2 interactions

NCOA2 ARID1B SMARCC1 ARID1A

2.17e-0556594int:TPRX2
InteractionRC3H1 interactions

ATXN2 FAM120C SMARCC1 YTHDC2 TNKS1BP1 RBM47 SPTY2D1 HNRNPH1 HNRNPH2 PRRC2B

2.43e-056775910int:RC3H1
InteractionFUBP3 interactions

ATXN2 FAM120C SMARCC1 FOXA1 RBM47 HNRNPH1 PRRC2B

2.49e-05297597int:FUBP3
InteractionGATA4 interactions

ZNF462 SMARCC1 CHD4 FOXA1 ARID1A SPTY2D1 HNRNPH1 HNRNPH2

2.50e-05411598int:GATA4
InteractionGATA2 interactions

ARID1B SMARCC1 SSBP2 ARID1A MIDEAS PRRC2B

2.51e-05199596int:GATA2
InteractionTEX13B interactions

ARID1B SMARCC1 ARID1A

2.62e-0520593int:TEX13B
InteractionFEV interactions

NCOA2 ZNF462 ARID1B ARID1A MIDEAS PRRC2B

2.80e-05203596int:FEV
InteractionSP7 interactions

NCOA2 ARID1B SUGP1 SMARCC1 ARID1A MIDEAS PRRC2B

2.89e-05304597int:SP7
InteractionNUP35 interactions

NCOA2 ARID1B ATXN2 SMARCC1 ARID1A MIDEAS RBM47 PRRC2B

3.12e-05424598int:NUP35
InteractionFLI1 interactions

ARID1B SMARCC1 PAX7 ARID1A

3.26e-0562594int:FLI1
InteractionNFIC interactions

SOX3 ARID1B PAX7 FOXA1 ARID1A MIDEAS

3.39e-05210596int:NFIC
InteractionATXN1 interactions

SOX3 GGA2 ADSL ATXN2 SUGP1 ELAVL4 CHD4 PAX7 ARID1A HNRNPH1 HNRNPH2 PRRC2B

3.91e-0510395912int:ATXN1
InteractionINPP5E interactions

TANC2 MAGI1 HNRNPH1 HNRNPH2

3.93e-0565594int:INPP5E
InteractionSMG7 interactions

NCOA2 ARID1B ATXN2 FAM120C ARID1A RBM47 PRRC2B

3.93e-05319597int:SMG7
InteractionSYNCRIP interactions

ATXN2 FAM120C ELAVL4 YTHDC2 CHD4 SSRP1 HNRNPH1 HNRNPH2 PRRC2B MAP3K4

4.15e-057215910int:SYNCRIP
InteractionRBM19 interactions

YTHDC2 CHD4 APOBEC3C FOXA1 RBM47 SPTY2D1

4.51e-05221596int:RBM19
InteractionNFIB interactions

ARID1B PAX7 FOXA1 ARID1A MIDEAS

5.97e-05142595int:NFIB
InteractionNANOG interactions

ZNF462 ARID1B SUGP1 CHD4 SSRP1 ARID1A MIDEAS HNRNPH2

7.57e-05481598int:NANOG
InteractionADARB1 interactions

SMARCC1 ELAVL4 YTHDC2 CHD4 SSRP1 SPTY2D1 HNRNPH1 HNRNPH2

8.49e-05489598int:ADARB1
InteractionHNRNPC interactions

FAM120C SMARCC1 CHD4 SSRP1 FOXA1 ARID1A RBM47 CWC22 HNRNPH1

8.79e-05634599int:HNRNPC
InteractionSOX7 interactions

NCOA2 ARID1B SMARCC1 ARID1A

9.77e-0582594int:SOX7
InteractionSTK11IP interactions

NPC1 ARID1B SMARCC1 ARID1A

1.02e-0483594int:STK11IP
InteractionYLPM1 interactions

SMARCC1 CHD4 SSRP1 FOXA1 HNRNPH1

1.05e-04160595int:YLPM1
InteractionR3HDM1 interactions

ATXN2 FAM120C RBM47 PRRC2B

1.07e-0484594int:R3HDM1
InteractionLSM14A interactions

COL8A1 ATXN2 FAM120C RBM47 HNRNPH1 PRRC2B

1.11e-04260596int:LSM14A
InteractionIRF4 interactions

ARID1B YTHDC2 ARID1A PRRC2B

1.12e-0485594int:IRF4
InteractionKIRREL3 interactions

TANC2 HNRNPH1

1.25e-046592int:KIRREL3
InteractionSS18 interactions

ARID1B SMARCC1 PAX7 ARID1A

1.29e-0488594int:SS18
InteractionRC3H2 interactions

ATXN2 FAM120C SMARCC1 YTHDC2 TNKS1BP1 RBM47 HNRNPH1 HNRNPH2 PRRC2B

1.29e-04667599int:RC3H2
InteractionCIC interactions

HGS SMARCC1 YTHDC2 CHD4 APOBEC3C PAX7 SSRP1 HNRNPH1 HNRNPH2

1.38e-04673599int:CIC
InteractionWWP2 interactions

ARID1B ATXN2 HGS SMARCC1 YTHDC2 SSRP1 ARID1A MIDEAS HNRNPH1 PRRC2B

1.48e-048405910int:WWP2
InteractionHNF4A interactions

NCOA2 ZNF462 ARID1B SMARCC1 ARID1A MIDEAS

1.50e-04275596int:HNF4A
InteractionARID1A interactions

ARID1B SMARCC1 CHD4 PAX7 SSRP1 ARID1A

1.53e-04276596int:ARID1A
InteractionFMR1 interactions

NCOA2 MAGI1 ATXN2 FAM120C ELAVL4 CHD4 BSN PRRC2B

1.60e-04536598int:FMR1
InteractionTEAD1 interactions

ZNF462 ARID1B SSBP2 ARID1A MIDEAS

1.64e-04176595int:TEAD1
InteractionSOX17 interactions

NCOA2 ARID1B ARID1A MIDEAS

1.73e-0495594int:SOX17
InteractionDPF1 interactions

ARID1B SMARCC1 PAX7 ARID1A

1.73e-0495594int:DPF1
InteractionSOX9 interactions

ARID1B SMARCC1 ARID1A MIDEAS

1.87e-0497594int:SOX9
InteractionCELF1 interactions

ATXN2 FAM120C SUGP1 RBM47 HNRNPH1 PRRC2B

1.93e-04288596int:CELF1
InteractionSMARCD2 interactions

ARID1B SMARCC1 CHD4 PAX7 ARID1A

1.97e-04183595int:SMARCD2
InteractionHNRNPUL2 interactions

ATXN2 CHD4 SSRP1 FOXA1 HNRNPH1 HNRNPH2

2.04e-04291596int:HNRNPUL2
InteractionATN1 interactions

MAGI1 HGS FOXA1 HNRNPH1 PRRC2B

2.18e-04187595int:ATN1
InteractionWWTR1 interactions

NCOA2 ARID1B SMARCC1 TNKS1BP1 SSRP1 ARID1A PRRC2B

2.24e-04422597int:WWTR1
InteractionCIT interactions

MAGI1 GPRASP1 DNAH12 CELSR2 HGS SMARCC1 YTHDC2 TNKS1BP1 CHD4 SSRP1 RBM47 HNRNPH2 MAP3K4

2.34e-0414505913int:CIT
InteractionRNF43 interactions

ATXN2 HGS YTHDC2 ARID1A HNRNPH1 HNRNPH2 PRRC2B

2.41e-04427597int:RNF43
InteractionTSG101 interactions

NPC1 ATXN2 FAM120C HGS TNKS1BP1 ITPRID2

2.54e-04303596int:TSG101
InteractionHDGFL2 interactions

ARID1B HTR2B SMARCC1 CHD4 SSRP1

2.58e-04194595int:HDGFL2
InteractionFOXP3 interactions

ADSL ATXN2 SUGP1 SMARCC1 CHD4 ARID1A MIDEAS

2.58e-04432597int:FOXP3
InteractionKLF5 interactions

NCOA2 ARID1B ARID1A HNRNPH1 PRRC2B

2.64e-04195595int:KLF5
InteractionSMARCAD1 interactions

SMARCC1 CHD4 SSRP1 RBM47 HNRNPH1

2.77e-04197595int:SMARCAD1
InteractionANKHD1-EIF4EBP3 interactions

ATXN2 FAM120C RBM47 PRRC2B

2.83e-04108594int:ANKHD1-EIF4EBP3
InteractionSPG21 interactions

NPC1 TANC2 GGA2 TOX2 HNRNPH1

2.90e-04199595int:SPG21
InteractionYAP1 interactions

TFEB ARID1B ADSL SMARCC1 TNKS1BP1 CHD4 SSRP1 FOXA1 ARID1A MIDEAS HNRNPH1

2.93e-0410955911int:YAP1
InteractionYTHDF2 interactions

ATXN2 FAM120C TNKS1BP1 RBM47 HNRNPH1 PRRC2B

2.97e-04312596int:YTHDF2
InteractionMECP2 interactions

ZNF462 ARID1B SUGP1 SMARCC1 TNKS1BP1 SSBP2 CHD4 SSRP1 ARID1A CWC22 HNRNPH1 HNRNPH2

2.97e-0412875912int:MECP2
InteractionLOC102724159 interactions

CHD4 FOXA1

2.99e-049592int:LOC102724159
InteractionGMEB1 interactions

NCOA2 SSRP1 HNRNPH1

3.10e-0445593int:GMEB1
InteractionPDCD6 interactions

ARID1B SMARCC1 ARID1A HNRNPH1 HNRNPH2

3.25e-04204595int:PDCD6
InteractionSIGLECL1 interactions

NPC1 FGFR2 CWC22 MAP3K4

3.36e-04113594int:SIGLECL1
InteractionTBR1 interactions

NCOA2 ARID1B ARID1A MIDEAS

3.36e-04113594int:TBR1
InteractionBCL7C interactions

ARID1B SMARCC1 PAX7 ARID1A

3.60e-04115594int:BCL7C
InteractionRAD18 interactions

SUGP1 SMARCC1 CHD4 APOBEC3C SSRP1 CWC22 SPTY2D1

3.63e-04457597int:RAD18
InteractionIWS1 interactions

COL8A1 CHD4 FGFR2 SSRP1

3.72e-04116594int:IWS1
InteractionPRELID3B interactions

PRELID3B HNRNPH1

3.73e-0410592int:PRELID3B
InteractionBRD9 interactions

ARID1B SMARCC1 ARID1A CWC22

3.84e-04117594int:BRD9
InteractionNR4A1 interactions

NCOA2 SMARCC1 CHD4 HNRNPH1 HNRNPH2

3.88e-04212595int:NR4A1
InteractionALKBH5 interactions

ADSL FOXA1 HNRNPH1

4.24e-0450593int:ALKBH5
InteractionETS1 interactions

ARID1B GGA2 SMARCC1 ARID1A

4.36e-04121594int:ETS1
InteractionEYA2 interactions

ARID1B HGS ARID1A PRRC2B

4.36e-04121594int:EYA2
Cytoband4p16.1

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

7.95e-08796254p16.1
CytobandEnsembl 112 genes in cytogenetic band chr4p16

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

1.31e-05222625chr4p16
Cytoband2q31.3

ITPRID2 CWC22

1.39e-04136222q31.3
GeneFamilySEC14 family|PRELI domain containing

PRELID3A PRELID3B

7.12e-0564021295
GeneFamilyAT-rich interaction domain containing

ARID1B ARID1A

4.92e-0415402418
GeneFamilyRNA binding motif containing

ELAVL4 RBM47 HNRNPH1 HNRNPH2

1.23e-03213404725
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K6 MAP3K4

1.28e-0324402654
GeneFamilyAtaxins|Trinucleotide repeat containing

MAGI1 ATXN2

1.39e-0325402775
GeneFamilyCollagens

COL8A1 COL22A1

4.64e-0346402490
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

SMARCC1 MIDEAS

6.12e-0353402532
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 MAGI1 ITPRID2 SLC12A7 NOS3

3.75e-06177595d68132e145bd413404fdbe215b5dbe520e756e50
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPC1 TANC2 GPRASP1 ARID1B HNRNPH1

6.32e-06197595e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 MAGI1 COL8A1 FGFR2 RBM47

6.64e-061995958587bd98de7767a575088afbea07a1feb4516b9b
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

MAGI1 PRELID3A TNKS1BP1 SSBP2

2.30e-0512559443aa4b77dccf0ea2979218826af16034f2017c3a
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GPRASP1 DNAH12 COL22A1 BSN

5.59e-05157594f6210be2362d833c6d869ff921188bfc85dda11d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GPRASP1 DNAH12 COL22A1 BSN

5.59e-0515759443a6b423fd70479822a564ff4225a1e4951ae5ed
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

ARID1B SMARCC1 CHD4 ARID1A

6.94e-0516659432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

SEMA3A TFEB FAM120C SSBP2

7.97e-05172594644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAGI1 HTR2B TOX2 NOS3

8.33e-0517459440bb87d219aafab0357ab0d797efd38085fc0312
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3A TFEB ITPRID2 SLC12A7

8.52e-05175594711ace94fa9a763c6ae48171a690953f25deebe4
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 ITPRID2 SLC12A7 NOS3

9.91e-05182594ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 ITPRID2 SLC12A7 NOS3

9.91e-0518259447ff6b4002a4167412c79210651316d1342503f9
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 ITPRID2 SLC12A7 NOS3

1.01e-0418359412e876d6205af8aad74265c668b5e95b9e7487f3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 TFEB SSBP2 ITPRID2

1.03e-04184594d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3A MINAR2 HTR2B NOS3

1.06e-0418559459acaf025353405948dc34ccccf37ec5c08ea903
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A TANC2 MAGI1 HTR2B

1.08e-04186594f23f21781a758541f59c06efa7739d26a03fb478
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A TANC2 MAGI1 HTR2B

1.08e-041865940de87109da9324c597fadf2eb782f0f158afe832
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A FGFR2 SLC12A7 NOS3

1.12e-041885944ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A FGFR2 SLC12A7 NOS3

1.12e-04188594e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPC1 TANC2 FGFR2 RBM47

1.12e-04188594562f5984efdbbcb8f53ddcee033ccbf9eb678425
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

SMARCC1 APOBEC3C FGFR2 SLC12A7

1.15e-04189594fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NCOA2 MAGI1 ARID1B SSBP2

1.15e-04189594830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

SMARCC1 APOBEC3C FGFR2 SLC12A7

1.15e-04189594b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 NCOA2 ARID1B RBM47

1.24e-04193594779276e775cb2492e8dd36436295a536084a6415
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF462 DNAH12 ELAVL4 BSN

1.24e-04193594088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SEMA3A TNKS1BP1 FGFR2 FOXA1

1.27e-041945942172d951896265243d14996eacce5aab5e14e26e
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 NCOA2 MAGI1 ARID1B

1.32e-04196594ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

ZNF462 CELSR2 ELAVL4 FGFR2

1.32e-0419659438da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

ZNF462 CELSR2 ELAVL4 FGFR2

1.32e-04196594721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellCaecum-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

NCOA2 CDHR2 FGFR2 NOS3

1.34e-0419759440c8ff067e8242e2ca083ea04cd6026168191a97
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 NCOA2 MAGI1 ARID1B

1.37e-041985941996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NPC1 TANC2 FGFR2 RBM47

1.37e-041985942e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

NCOA2 MAGI1 ARID1B SSBP2

1.40e-0419959494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TANC2 GPRASP1 CELSR2 ELAVL4

1.40e-04199594f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

NCOA2 MAGI1 ARID1A HNRNPH1

1.42e-04200594d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

SOX3 SMARCC1 ELAVL4 PRRC2B

1.42e-042005942a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

TANC2 CELSR2 CHD4 PRRC2B

1.42e-04200594c92e4fc0442404481fcac623d691dae6215b852d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell|GW13 / Sample Type, Dataset, Time_group, and Cell type.

NCOA2 MAGI1 ARID1A HNRNPH1

1.42e-042005943d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCelllymphoid-T_cell-pro-T_cell|World / Lineage, cell class and subclass

GPRASP1 MIDEAS HNRNPH1

1.64e-04805939bd3ad5029eb84efcdbf08fe268c29fa9b0b302b
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

TANC2 NCOA2 MAGI1 GGA2 SUGP1 SSBP2

7.71e-061895765248_DN
DrugButylparaben [94-26-8]; Down 200; 20.6uM; PC3; HT_HG-U133A

SEMA3A GPRASP1 GGA2 CELSR2 SSBP2 PRRC2B

8.19e-061915764647_DN
DrugSpiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A

TFEB FAM120C SUGP1 SMARCC1 CHD4 HNRNPH1

8.96e-061945764319_DN
DrugDemeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A

NCOA2 MAGI1 GGA2 FAM120C YTHDC2 HNRNPH1

9.50e-061965764728_DN
DrugNalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A

TANC2 COL8A1 CDHR2 FAM120C SUGP1 HNRNPH1

1.04e-051995767367_UP
DrugZaprinast [37762-06-4]; Down 200; 14.8uM; PC3; HT_HG-U133A

TANC2 COL8A1 GGA2 SSBP2 ARID1A

1.22e-041935756749_DN
DrugOmeprazole [73590-58-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A

NCOA2 GGA2 SUGP1 HNRNPH1 PRRC2B

1.22e-041935754951_DN
DrugCP-690334-01 [459212-38-5]; Down 200; 10uM; MCF7; HT_HG-U133A

TANC2 GGA2 SUGP1 CHD4 FGFR2

1.22e-041935753906_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

NCOA2 COL8A1 FAM120C SUGP1 APOBEC3C

1.22e-041935752721_DN
DrugQuercetine dihydrate [6151-25-3]; Down 200; 11.8uM; PC3; HT_HG-U133A

NCOA2 GGA2 PRELID3A YTHDC2 SSBP2

1.25e-041945754264_DN
DrugRifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A

NCOA2 COL8A1 FAM120C SUGP1 FGFR2

1.25e-041945754126_DN
DrugTrifluridine [70-00-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

NCOA2 COL8A1 FGFR2 HNRNPH1 PRRC2B

1.28e-041955753559_DN
DrugClomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; MCF7; HT_HG-U133A

MAGI1 GPRASP1 SUGP1 ITPRID2 HNRNPH1

1.28e-041955754994_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

GPRASP1 PRELID3A FAM120C SUGP1 HNRNPH1

1.28e-041955753721_DN
DrugS(+)-Terguride [37686-84-3]; Up 200; 11.8uM; PC3; HT_HG-U133A

GGA2 CELSR2 CDHR2 SUGP1 SMARCC1

1.28e-041955756299_UP
DrugMidodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A

TFEB GGA2 CELSR2 SUGP1 PRRC2B

1.28e-041955752087_UP
DrugDO 897/99; Up 200; 8.2uM; HL60; HG-U133A

GGA2 ATXN2 CDHR2 ELAVL4 SSBP2

1.31e-041965751728_UP
Drugestradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA

TANC2 NCOA2 GGA2 YTHDC2 FGFR2

1.31e-041965751021_DN
DrugDiphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; PC3; HT_HG-U133A

TANC2 NCOA2 PRELID3A ZNF334 SUGP1

1.31e-041965754591_DN
DrugOxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A

COL8A1 GGA2 PRELID3A FAM120C FGFR2

1.31e-041965755338_UP
DrugTrimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; PC3; HT_HG-U133A

NCOA2 SUGP1 SSBP2 ARID1A MAP3K6

1.31e-041965755060_DN
DrugPilocarpine nitrate [148-72-1]; Down 200; 14.8uM; HL60; HT_HG-U133A

NCOA2 TFEB COL8A1 SUGP1 ARID1A

1.31e-041965752438_DN
DrugDesipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A

NCOA2 GGA2 FGFR2 ARID1A PRRC2B

1.34e-041975755292_DN
DrugCP-320650-01 [172079-28-6]; Down 200; 10uM; PC3; HT_HG-U133A

COL8A1 GGA2 PRELID3A SUGP1 HNRNPH1

1.34e-041975754557_DN
DrugDihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; PC3; HT_HG-U133A

TFEB GGA2 CELSR2 SUGP1 SSBP2

1.34e-041975752074_UP
DrugLansoprazole [103577-45-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A

CDHR2 SUGP1 ELAVL4 HNRNPH1 PRRC2B

1.34e-041975756009_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 10uM; MCF7; HT_HG-U133A

MAGI1 GGA2 SUGP1 FGFR2 MAP3K4

1.34e-041975753629_DN
DrugJosamycin [16846-24-5]; Down 200; 4.8uM; HL60; HG-U133A

ATXN2 ARID1A HNRNPH2 PRRC2B MAP3K4

1.34e-041975752034_DN
DrugHyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A

TFEB COL8A1 ZNF334 FAM120C SSBP2

1.34e-041975755099_UP
DrugIsoniazid [54-85-3]; Up 200; 29.2uM; PC3; HT_HG-U133A

COL8A1 GGA2 CDHR2 FAM120C HNRNPH1

1.34e-041975755840_UP
DrugNaloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A

GPRASP1 SUGP1 YTHDC2 FGFR2 MAP3K6

1.37e-041985751506_DN
DrugChlormezanone [80-77-3]; Down 200; 14.6uM; PC3; HT_HG-U133A

NCOA2 TFEB GGA2 CELSR2 FGFR2

1.37e-041985754636_DN
DrugEpitiostanol [2363-58-8]; Down 200; 13uM; MCF7; HT_HG-U133A

TANC2 SUGP1 YTHDC2 MAP3K6 HNRNPH1

1.37e-041985754788_DN
DrugNilutamide [63612-50-0]; Down 200; 12.6uM; MCF7; HT_HG-U133A

NCOA2 COL8A1 GGA2 PRELID3A SUGP1

1.37e-041985756481_DN
DrugEtofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A

NCOA2 COL8A1 FAM120C SUGP1 SMARCC1

1.37e-041985752256_DN
Drugrosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A

TFEB CELSR2 CDHR2 SUGP1 FGFR2

1.40e-041995752693_DN
DrugDecamethonium bromide [541-22-0]; Down 200; 9.6uM; HL60; HT_HG-U133A

GGA2 SUGP1 APOBEC3C ARID1A PRRC2B

1.40e-041995752933_DN
Drug2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; PC3; HT_HG-U133A

TFEB GPRASP1 GGA2 SUGP1 SSBP2

1.40e-041995756321_DN
DrugTracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; HL60; HT_HG-U133A

SEMA3A TANC2 PRELID3A CDHR2 MAP3K6

1.44e-042005752919_UP
Drug2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester

SEMA3A TFEB GPRASP1 COL8A1 SSBP2 FGFR2 ITPRID2 BSN NOS3

1.65e-04807579ctd:C548651
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

3.17e-0846585DOID:5426 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP17L21 USP17L12 USP17L20 USP17L24 USP17L5

2.51e-0769585DOID:1682 (implicated_via_orthology)
DiseaseEndometrial Neoplasms

CHD4 FGFR2 ARID1A MAP3K4

5.27e-0658584C0014170
DiseasePtosis

ZNF462 PAX7

1.14e-053582C0033377
DiseaseBlepharoptosis

ZNF462 PAX7

1.14e-053582C0005745
DiseaseEndometrial Carcinoma

CHD4 FGFR2 ARID1A MAP3K4

1.25e-0572584C0476089
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1B ARID1A

3.78e-055582C3281201
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1B FOXA1 ARID1A

7.29e-0541583C0496956
DiseaseBreast adenocarcinoma

ARID1B FOXA1 ARID1A

7.29e-0541583C0858252
Diseasenon-high density lipoprotein cholesterol measurement

NPC1 CELSR2 ATXN2 SUGP1 ARID1A MIDEAS MAP3K6 SPTY2D1

7.38e-05713588EFO_0005689
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

CELSR2 ATXN2 SUGP1 ARID1A MAP3K4

7.96e-05224585EFO_0004574, EFO_0008317
Diseasegeneralized anxiety disorder (implicated_via_orthology)

ZNF462 HTR2B

1.06e-048582DOID:14320 (implicated_via_orthology)
DiseaseNeuroblastoma

RASSF5 ARID1B ARID1A

1.10e-0447583C0027819
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCC1 ARID1A

1.35e-049582DOID:1925 (implicated_via_orthology)
Diseaseserum albumin measurement

TFEB ATXN2 SMARCC1 FGFR2 BSN RBM47 SPTY2D1

1.57e-04592587EFO_0004535
Diseaseneuroblastoma (is_implicated_in)

ARID1B ARID1A

1.69e-0410582DOID:769 (is_implicated_in)
Diseasestomach cancer (is_marker_for)

NCOA2 FGFR2 FOXA1 ARID1A

1.78e-04142584DOID:10534 (is_marker_for)
Diseasebreast cancer (is_implicated_in)

FGFR2 FOXA1 ARID1A NOS3

2.20e-04150584DOID:1612 (is_implicated_in)
DiseaseMalignant neoplasm of breast

SEMA3A NCOA2 ARID1B LIPE FGFR2 FOXA1 ARID1A MAP3K6 NOS3

2.32e-041074589C0006142
Diseaseapolipoprotein A 1 measurement

NPC1 NCOA2 CELSR2 ATXN2 SMARCC1 TNKS1BP1 ARID1A MIDEAS

2.42e-04848588EFO_0004614
Diseaseesophagus adenocarcinoma (is_marker_for)

FOXA1 ARID1A

2.47e-0412582DOID:4914 (is_marker_for)
Diseaseright ventricular stroke volume measurement

ATXN2 NOS3

2.47e-0412582EFO_0021817
Diseasetriglycerides in medium LDL measurement

CELSR2 SUGP1 ARID1A

2.51e-0462583EFO_0022322
Diseasecolorectal cancer (is_marker_for)

SMARCC1 CHD4 FOXA1 ARID1A

2.62e-04157584DOID:9256 (is_marker_for)
Diseasecortical surface area measurement

TANC2 NCOA2 MAGI1 ARID1B ATXN2 SSBP2 COL22A1 FGFR2 PAX7 HNRNPH1

2.65e-0413455810EFO_0010736
Diseasetriglycerides in small LDL measurement

CELSR2 SUGP1 ARID1A

2.89e-0465583EFO_0022323
DiseaseCoffin-Siris syndrome

ARID1B ARID1A

2.92e-0413582C0265338
Diseaseapolipoprotein B measurement

CELSR2 ATXN2 SUGP1 ARID1A MIDEAS RBM47 SPTY2D1

3.12e-04663587EFO_0004615
Diseasehepatocellular carcinoma (is_marker_for)

SMARCC1 CHD4 FOXA1 ARID1A HNRNPH1

3.15e-04301585DOID:684 (is_marker_for)
Diseasetissue plasminogen activator measurement, coronary artery disease

CELSR2 ATXN2 MAP3K4

3.75e-0471583EFO_0001645, EFO_0004791
Diseasestomach cancer (is_implicated_in)

FGFR2 FOXA1 ARID1A

3.90e-0472583DOID:10534 (is_implicated_in)
Diseaselysosomal storage disease (implicated_via_orthology)

TFEB GGA2

4.48e-0416582DOID:3211 (implicated_via_orthology)
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

CELSR2 SUGP1

5.69e-0418582EFO_0008317, EFO_0008589
DiseaseBreast Carcinoma

NCOA2 ARID1B FGFR2 FOXA1 ARID1A NOS3

6.48e-04538586C0678222
Diseaseliver fibrosis measurement

COL8A1 CELSR2 SUGP1

6.57e-0486583EFO_0010576
DiseaseCraniosynostosis

ZNF462 FGFR2

7.05e-0420582C0010278
Diseasetestosterone measurement

SEMA3A TFEB MAGI1 ARID1B LIPE TNKS1BP1 ARID1A MIDEAS CWC22

8.06e-041275589EFO_0004908
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

CELSR2 SUGP1 ARID1A MAP3K4

8.55e-04215584EFO_0008317, EFO_0008591
Diseaseportal hypertension (biomarker_via_orthology)

FGFR2 NOS3

8.55e-0422582DOID:10762 (biomarker_via_orthology)
Diseaseprogranulin measurement

NCOA2 CELSR2

8.55e-0422582EFO_0004625
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

CELSR2 SUGP1 ARID1A MAP3K4

9.31e-04220584EFO_0004529, EFO_0008317
DiseaseOvarian Serous Adenocarcinoma

FGFR2 MAP3K4

9.36e-0423582C1335177
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

CELSR2 ARID1A SPTY2D1

9.89e-0499583EFO_0004611, EFO_0007878
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

CELSR2 ATXN2 ARID1A MAP3K4

1.01e-03225584EFO_0008317, EFO_0010351
DiseaseIntrahepatic Cholangiocarcinoma

FGFR2 ARID1A

1.02e-0324582C0345905
DiseaseExtrahepatic Cholangiocarcinoma

FGFR2 ARID1A

1.02e-0324582C3805278
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

CELSR2 ARID1A SPTY2D1

1.08e-03102583EFO_0004329, EFO_0004611
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

CELSR2 SUGP1 ARID1A MAP3K4

1.08e-03229584EFO_0004639, EFO_0008317
DiseaseKallmann Syndrome

SOX3 SEMA3A

1.20e-0326582C0162809
DiseaseCholangiocarcinoma

FGFR2 ARID1A

1.20e-0326582C0206698
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

CELSR2 ARID1A MIDEAS

1.24e-03107583EFO_0004614, EFO_0004615
Diseaseremnant cholesterol measurement

CELSR2 ATXN2 SUGP1

1.27e-03108583EFO_0010815
Diseaseeye measurement

SEMA3A ATXN2

1.29e-0327582EFO_0004731
DiseaseProstatic Neoplasms

NCOA2 SSBP2 FOXA1 ARID1A NOS3 HNRNPH1

1.30e-03616586C0033578
DiseaseMalignant neoplasm of prostate

NCOA2 SSBP2 FOXA1 ARID1A NOS3 HNRNPH1

1.30e-03616586C0376358
Diseasecoronary artery disease, factor VII measurement

CELSR2 ATXN2 NOS3

1.38e-03111583EFO_0001645, EFO_0004619
Diseaseright ventricular diastolic volume measurement

ATXN2 NOS3

1.39e-0328582EFO_0021814
Diseaselipoprotein A measurement

ARID1B CELSR2 MAP3K4

1.41e-03112583EFO_0006925
DiseaseBilateral Wilms Tumor

ARID1A MAP3K4

1.49e-0329582C2930471
Diseaselongevity, healthspan, parental longevity

CELSR2 ATXN2

1.49e-0329582EFO_0004300, EFO_0007796, EFO_0009762
Diseasefactor XI measurement, coronary artery disease

CELSR2 ATXN2 NOS3

1.52e-03115583EFO_0001645, EFO_0004694
DiseaseCarcinoma, Granular Cell

SMARCC1 ARID1A NOS3

1.56e-03116583C0205644
DiseaseAdenocarcinoma, Tubular

SMARCC1 ARID1A NOS3

1.56e-03116583C0205645
DiseaseAdenocarcinoma, Oxyphilic

SMARCC1 ARID1A NOS3

1.56e-03116583C0205642
DiseaseCarcinoma, Cribriform

SMARCC1 ARID1A NOS3

1.56e-03116583C0205643
DiseaseAdenocarcinoma, Basal Cell

SMARCC1 ARID1A NOS3

1.56e-03116583C0205641
DiseaseAdenocarcinoma

SMARCC1 ARID1A NOS3

1.56e-03116583C0001418
Diseasevon Willebrand factor measurement, coronary artery disease

CELSR2 ATXN2 NOS3

1.64e-03118583EFO_0001645, EFO_0004629
Diseasecholesteryl ester measurement

CELSR2 ATXN2 SUGP1 ARID1A

1.65e-03257584EFO_0010351
Diseasecancer (implicated_via_orthology)

ARID1B SMARCC1 SSRP1 ARID1A

1.92e-03268584DOID:162 (implicated_via_orthology)
Diseaseprostate cancer (implicated_via_orthology)

FGFR2 PAX7

1.93e-0333582DOID:10283 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GINPAMYQSPMRLRS

HTR2B

436

P41595
MNPQIRNPMKAMYPG

APOBEC3C

1

Q9NRW3
NMAYGVKRLMSGPVP

ELAVL4

256

P26378
MKRPQLYGMGSNPHS

ARID1B

606

Q8NFD5
AYAVDKGMPPARTPM

CELSR2

891

Q9HCU4
AQYSMFPAAPAPKMI

RBM47

451

A0AV96
MAMASPAIGQRPYPL

RASSF5

1

Q8WWW0
GTVPRMMRPAPGQNY

PAX7

6

P23759
MMRPAPGQNYPRTGF

PAX7

11

P23759
SSPMDQMGKMRPQPY

ARID1A

381

O14497
QMGKMRPQPYGGTNP

ARID1A

386

O14497
KRNSMTPNPGYQPSM

ARID1A

1201

O14497
QPNLMPSNPDSGMYS

ARID1A

1306

O14497
KFRCPAGGNPMPTMR

FGFR2

176

P21802
MYENRPMSPSPASGL

MAGI1

801

Q96QZ7
YSPVIQGNARMMAPP

ATXN2

1066

Q99700
AYMDPMKQNGGPLTP

BSN

1296

Q9UPA5
GAYIPPAKLRMMQEQ

CWC22

131

Q9HCG8
QVGMYKVHPPMPSSL

MAP3K6

861

O95382
DPPRKLMAMQRPGPY

HNRNPH2

196

P55795
PPSMSSVMKNNPLYG

MINAR2

81

P59773
LAMYPNLGKDMPPDL

FAM47B

131

Q8NA70
DMNMPALEKYGAQPP

DNAH12

1961

Q6ZR08
QEMLSMYRRPGQAPP

GGA2

246

Q9UJY4
DPPRKLMAMQRPGPY

HNRNPH1

196

P31943
NLSQYPMMRGPDPAA

ITPRID2

926

P28290
MEMSGPYNSSPRPEQ

NOS3

591

P29474
MRFLPMFLSDNPNPK

NPC1

996

O15118
PCMSPMAYAPSNLGR

FOXA1

136

P55317
VMPSAPAIPGTNMYN

CDHR2

1201

Q9BYE9
YLPMQGNPPRRSKSA

CENPJ

1096

Q9HC77
LYSRAMGSMPLPPQG

FAM120C

926

Q9NX05
LPQYMKEIQPAPRMG

COL8A1

86

P27658
QMPPAYMKSSQGRPG

COL22A1

1486

Q8NFW1
GGPQLDRYVRPMMPQ

MIDEAS

171

Q6PJG2
GMGRRQVMPPKYNFP

FAM237B

111

A0A1B0GVD1
RKAFLNAIMRYGMPP

CHD4

1421

Q14839
MPGPPKNRQGDENYM

SLC12A7

1041

Q9Y666
PDGIMAAYPATMLQP

LIPE

746

Q05469
YGTSPPSTPRQMKRM

MAP3K4

81

Q9Y6R4
FLENMIRMAPPYPNL

GPRASP1

1216

Q5JY77
PMMPPGAQSYMNVAA

SOX3

311

P41225
DNMYTLMNAVPPGPN

SSBP2

266

P81877
LGYINPEMQMPNTLP

TFEB

171

P19484
AMQKYPNPMNPSVVG

PRELID3B

21

Q9Y3B1
QIGSSAMPYKRNPMR

ADSL

286

P30566
AMRKYPNPMNPSVLG

PRELID3A

21

Q96N28
LSKMAQRPYQMPQLP

TANC2

1581

Q9HCD6
HPAMYNPVFPMNNRP

SEMA3A

406

Q14563
MNGMKPPLSGYRAAQ

SPTY2D1

556

Q68D10
NYQVDPESRPMAMGP

SMARCC1

536

Q92922
GKDPNAPKRPMSAYM

SSRP1

541

Q08945
RNSSPYSVIPQPGMM

NCOA2

906

Q15596
MMLAYRFRPNPLNNP

SUGP1

626

Q8IWZ8
NLGMNSVPSRKMPYK

ZNF334

121

Q9HCZ1
PSARKMNMLAGPQPY

TNKS1BP1

76

Q9C0C2
MRAQMPAFPLPYAQL

HGS

556

O14964
LDMQPYMSQPNTGPL

USP17L5

301

A8MUK1
LDMQPYMSQPNTGPL

USP17L21

301

D6R901
PYSAFPGMQPLEMVK

PRRC2B

2021

Q5JSZ5
LEMVKPQSGSPYQPM

PRRC2B

2031

Q5JSZ5
RSMQVYPMPQDFVPG

TEX13C

151

A0A0J9YWL9
LDMQPYMSQPNTGPL

USP17L12

301

C9JPN9
SPRPNMPVRYFIMKS

YTHDC2

1281

Q9H6S0
LDMQPYMSQPNTGPL

USP17L24

301

Q0WX57
QPMYAMPGLASFLTP

TOX2

326

Q96NM4
MSYPQMKPKSPHNSG

ZNF462

341

Q96JM2
LDMQPYMSQPNTGPL

USP17L20

301

D6RJB6