Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-arginine omega-N symmetric methyltransferase activity

NDUFAF7 PRMT7

1.04e-044842GO:0035243
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

FAT1 DSC1 DSC2 HMCN1 PECAM1 PCDH11X PCDHA2 CDHR4

7.90e-07187828GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

FAT1 DSC1 DSC2 HMCN1 PECAM1 PCDH11X PCDHA2 CDHR4

3.46e-05313828GO:0098742
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

PIK3CA ERC1 PAPSS1 TRRAP CCNK CHUK POLR3F

3.73e-04335837GO:0061695
GeneOntologyCellularComponentIkappaB kinase complex

ERC1 CHUK

4.29e-048832GO:0008385
GeneOntologyCellularComponentRNA polymerase III transcription regulator complex

BDP1 GTF3C4

5.51e-049832GO:0090576
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1A CACNA1E CATSPER4

8.10e-0446833GO:0005891
GeneOntologyCellularComponentCD40 receptor complex

TRAF5 CHUK

8.37e-0411832GO:0035631
DomainCadherin_CS

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

8.40e-06109826IPR020894
DomainCADHERIN_1

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

1.03e-05113826PS00232
DomainCadherin

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

1.03e-05113826PF00028
DomainCADHERIN_2

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

1.09e-05114826PS50268
Domain-

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

1.09e-051148262.60.40.60
DomainCA

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

1.14e-05115826SM00112
DomainCadherin-like

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

1.20e-05116826IPR015919
DomainCadherin

FAT1 DSC1 DSC2 PCDH11X PCDHA2 CDHR4

1.33e-05118826IPR002126
Domain-

SMG1 PIK3CA TRRAP

4.38e-05168231.10.1070.11
DomainPI3Kc

SMG1 PIK3CA TRRAP

4.38e-0516823SM00146
DomainPI3/4_kinase_cat_dom

SMG1 PIK3CA TRRAP

6.35e-0518823IPR000403
DomainPI3_PI4_kinase

SMG1 PIK3CA TRRAP

6.35e-0518823PF00454
DomainPI3_4_KINASE_3

SMG1 PIK3CA TRRAP

6.35e-0518823PS50290
DomainPI3_4_KINASE_1

SMG1 PIK3CA TRRAP

6.35e-0518823PS00915
DomainPI3_4_KINASE_2

SMG1 PIK3CA TRRAP

6.35e-0518823PS00916
DomainFAT

SMG1 TRRAP

2.82e-046822PS51189
DomainFATC

SMG1 TRRAP

2.82e-046822PS51190
DomainFATC_dom

SMG1 TRRAP

2.82e-046822IPR003152
DomainPIK_FAT

SMG1 TRRAP

2.82e-046822IPR014009
DomainFATC

SMG1 TRRAP

2.82e-046822SM01343
DomainVDCC_a1su_IQ

CACNA1A CACNA1E

3.94e-047822IPR014873
DomainDesmosomal_cadherin

DSC1 DSC2

3.94e-047822IPR009122
DomainGPHH

CACNA1A CACNA1E

3.94e-047822PF16905
DomainGPHH_dom

CACNA1A CACNA1E

3.94e-047822IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1E

3.94e-047822SM01062
DomainCadherin_pro

DSC1 DSC2

3.94e-047822PF08758
DomainCa_chan_IQ

CACNA1A CACNA1E

3.94e-047822PF08763
DomainCadherin_pro_dom

DSC1 DSC2

5.24e-048822IPR014868
DomainCadherin_pro

DSC1 DSC2

5.24e-048822SM01055
DomainVDCCAlpha1

CACNA1A CACNA1E

8.38e-0410822IPR002077
DomainPI3/4_kinase_CS

SMG1 PIK3CA

1.93e-0315822IPR018936
DomainChannel_four-helix_dom

CACNA1A CACNA1E CATSPER4

2.01e-0357823IPR027359
Domain-

CACNA1A CACNA1E CATSPER4

2.01e-03578231.20.120.350
DomainHEAT_REPEAT

SMG1 RANBP6 PDS5A

3.61e-0370823PS50077
DomainARM-type_fold

SMG1 ARMC12 PIK3CA RANBP6 PDS5A TRRAP

3.77e-03339826IPR016024
DomainDEAD/DEAH_box_helicase_dom

BLM DDX42 DDX1

4.07e-0373823IPR011545
DomainDEAD

BLM DDX42 DDX1

4.07e-0373823PF00270
DomainCadherin_cytoplasmic-dom

DSC1 DSC2

5.35e-0325822IPR000233
DomainCadherin_C

DSC1 DSC2

5.35e-0325822PF01049
DomainARM-like

SMG1 ARMC12 RANBP6 PDS5A TRRAP

6.72e-03270825IPR011989
DomainCatenin_binding_dom

DSC1 DSC2

7.16e-0329822IPR027397
Domain-

DSC1 DSC2

7.16e-03298224.10.900.10
DomainDEAD_ATP_HELICASE

DDX42 DDX1

8.15e-0331822PS00039
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A CACNA1E ERC1

4.72e-07784335176221
Pubmed

Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.

FAT1 DSC1 DSC2

1.61e-061084312724416
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

SMG1 MLST8 TRRAP

2.21e-061184320427287
Pubmed

Differential synthesis of type 1 and type 2 desmocollin mRNAs in human stratified epithelia.

DSC1 DSC2

5.76e-0628428507556
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

5.76e-06284216381801
Pubmed

ELKS1 and Ca(2+) channel subunit β4 interact and colocalize at cerebellar synapses.

CACNA1A ERC1

1.73e-05384222107844
Pubmed

Desmocollin switching in colorectal cancer.

DSC1 DSC2

1.73e-05384217088906
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1E

1.73e-05384238996073
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1E

1.73e-05384224523520
Pubmed

The influence of desmocollin 1-3 expression on prognosis after curative resection of colorectal liver metastases.

DSC1 DSC2

1.73e-05384223975055
Pubmed

Compositionally different desmosomes in the various compartments of the human hair follicle.

DSC1 DSC2

1.73e-0538429810708
Pubmed

Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development.

DSC1 DSC2

1.73e-0538429389456
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1E

3.45e-05484232616470
Pubmed

Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation.

PECAM1 CHUK

3.45e-05484210898787
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1E

3.45e-05484237141091
Pubmed

CAST/ELKS Proteins Control Voltage-Gated Ca2+ Channel Density and Synaptic Release Probability at a Mammalian Central Synapse.

CACNA1A ERC1

3.45e-05484229996090
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1E

5.74e-0558428825650
Pubmed

An anti-interferon activity shared by paramyxovirus C proteins: inhibition of Toll-like receptor 7/9-dependent alpha interferon induction.

TLR7 CHUK

5.74e-05584224269682
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1E

5.74e-05584215451373
Pubmed

IKK/NF-kappaB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors.

TRRAP CHUK

5.74e-05584218542057
Pubmed

Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.

DSC1 DSC2

5.74e-05584222438068
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1E

5.74e-05584211296258
Pubmed

Nomenclature of the desmosomal cadherins.

DSC1 DSC2

5.74e-0558428486729
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

PDIA6 DSC1 ERC1 DDX42 PEPD CTPS1 PRMT7 NEK9 CCNK GTF3C4

8.53e-05934841033916271
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1E

8.59e-05684235324301
Pubmed

IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9.

TLR7 CHUK

8.59e-05684216612387
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

CACNA1A CACNA1E

8.59e-05684212827191
Pubmed

Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit.

ERC1 CHUK

8.59e-05684215218148
Pubmed

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

CACNA1A CACNA1E

8.59e-0568429238069
Pubmed

Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.

BDP1 POLR3F

8.59e-0568429171375
Pubmed

Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse.

DSC1 DSC2

8.59e-0568429404003
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

SMG1 DDX42 PRMT7 NEK9

1.17e-0410384429539633
Pubmed

HIV-1 Nef interacts with HCV Core, recruits TRAF2, TRAF5 and TRAF6, and stimulates HIV-1 replication in macrophages.

TRAF5 CHUK

1.20e-04784223774506
Pubmed

Bruton's tyrosine kinase and protein kinase C µ are required for TLR7/9-induced IKKα and IRF-1 activation and interferon-β production in conventional dendritic cells.

TLR7 CHUK

1.20e-04784225170774
Pubmed

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway.

TRAF5 CHUK

1.20e-04784212842894
Pubmed

IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway.

PIK3CA CHUK

1.20e-04784223778976
Pubmed

P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.

MLST8 PREX2

1.20e-04784217565979
Pubmed

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.

PECAM1 MLST8

1.20e-04784217141160
Pubmed

Myristoylated p110α Causes Embryonic Death Due to Developmental and Vascular Defects.

PIK3CA PECAM1

1.60e-04884227482546
Pubmed

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways.

NLRC5 CHUK

1.60e-04884220434986
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

BLM SSU72 DDX42 PDS5A PAPSS1 TRRAP CCNK GTF3C4 DDX1 POLR3F

1.67e-041014841032416067
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

SMG1 BCL2L14 PDIA6 COG7 ACAD9 SIPA1L1 RANBP6 PDS5A CTPS1 DDX1 LRCH3 CHUK

1.74e-041440841230833792
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

DDX42 PDS5A TRRAP GTF3C4 DDX1

1.99e-0422084535785414
Pubmed

Critical role of IkappaB Kinase alpha in TLR7/9-induced type I IFN production by conventional dendritic cells.

TLR7 CHUK

2.05e-04984220200270
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1E

2.05e-04984216382099
Pubmed

Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2.

TRAF5 CHUK

2.05e-04984217384642
Pubmed

A Cellular Mechanism to Detect and Alleviate Reductive Stress.

FEM1B FNIP1

2.05e-04984232941802
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 INTS2 PEPD LAMA3 CDK5RAP1 NLRC5 FNIP1 MCF2L USP15 TRRAP NEK9 LRCH3

2.37e-041489841228611215
Pubmed

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.

TRAF5 CHUK

2.56e-041084218079694
Pubmed

Haploinsufficiency of Klippel-Trenaunay syndrome gene Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherin.

PIK3CA PECAM1

2.56e-041084227522498
Pubmed

Tel2 regulates the stability of PI3K-related protein kinases.

SMG1 TRRAP

2.56e-041084218160036
Pubmed

Structural basis and regulation of the reductive stress response.

FEM1B FNIP1

2.56e-041084234562363
Pubmed

ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.

ERC1 CHUK

2.56e-041084220932476
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

FEM1B SMG1 SIPA1L1

2.76e-04528439455477
Pubmed

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

PIK3CA PECAM1

3.13e-041184218449193
Pubmed

Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology.

ACHE PECAM1

3.13e-041184222992950
Pubmed

Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling.

DSC1 DSC2

3.13e-041184211790773
Pubmed

Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma.

TRAF5 CHUK

3.13e-041184218990758
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

PECAM1 LAMA3

3.13e-041184212051813
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

DSC1 ACAD9 CDK5RAP1 CTPS1 DDX1

3.27e-0424584535652658
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

BLM ERC1 ACAD9 SIPA1L1 MLST8 USP15 NEK9 TCTN1 GTF3C4 DDX1 LRCH3

3.33e-041321841127173435
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ERC1 CTPS1 USP15 TRRAP NEK9 CCNK GTF3C4

3.73e-0454984738280479
Pubmed

Pathogen recognition in the innate immune response.

TLR7 CHUK

3.75e-041284219382893
Pubmed

High-resolution mapping of mouse chromosome 8 identifies an evolutionary chromosomal breakpoint.

CACNA1A FAT1

3.75e-04128429680377
Pubmed

Defining desmosomal plakophilin-3 interactions.

DSC1 DSC2

3.75e-041284212707304
Pubmed

The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity.

GTF3C4 POLR3F

3.75e-041284210523658
Pubmed

USP13 interacts with cohesin and regulates its ubiquitination in human cells.

DSC1 PDS5A

3.75e-041284233334891
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

PECAM1 LAMA3

3.75e-041284216750824
Pubmed

Parkin regulates NF-κB by mediating site-specific ubiquitination of RIPK1.

TRAF5 CHUK

3.75e-041284229955050
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

SIPA1L1 PDS5A CTPS1 USP15 GTF3C4 DDX1

4.20e-0439984637536630
Pubmed

HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.

TRAF5 CHUK

4.42e-041384220614026
Pubmed

Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development.

PIK3CA PECAM1

4.42e-041384237704707
Pubmed

Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.

PIK3CA PECAM1

4.42e-041384227050100
Pubmed

Assessment of splice variant-specific functions of desmocollin 1 in the skin.

DSC1 DSC2

4.42e-041384214673151
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NAA35 PDIA6 DSC2 ERC1 ACAD9 RANBP6 PDS5A GALNT12 DDX1

4.52e-0494284931073040
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

BLM JOSD1 MLST8 USP15

4.55e-0414784429576527
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FEM1B ERC1 SIPA1L1 FNIP1 MCF2L USP15

4.66e-0440784612693553
Pubmed

Differential signaling mechanism for HIV-1 Nef-mediated production of IL-6 and IL-8 in human astrocytes.

PIK3CA CHUK

5.15e-041484226075907
Pubmed

Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.

CACNA1A ERC1

5.15e-041484221228161
Pubmed

Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.

TLR7 CHUK

5.15e-041484230131424
Pubmed

Astrocyte-intrinsic and -extrinsic Fat1 activities regulate astrocyte development and angiogenesis in the retina.

FAT1 PECAM1

5.15e-041484235050341
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

DSC1 INTS2 PDS5A TRRAP GTF3C4

5.26e-0427284531010829
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BLM PDIA6 SIPA1L1 PEPD CTPS1 TRRAP CCNK GTF3C4

5.71e-0477484815302935
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1A CACNA1E

5.93e-041584220188150
Pubmed

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

TRIM64 CHUK

5.93e-041584219703589
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1A CACNA1E

5.93e-041584224453333
Pubmed

Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice.

DSC1 DSC2

5.93e-04158429847250
Pubmed

A single-cell atlas of mouse lung development.

PECAM1 LAMA3

5.93e-041584234927678
Pubmed

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

PDIA6 ACAD9 CTPS1 CCNK DDX1

6.29e-0428384528533407
Pubmed

Desmocollin 3 is required for pre-implantation development of the mouse embryo.

DSC1 DSC2

6.77e-041684216418220
Pubmed

IRF6 and AP2A Interaction Regulates Epidermal Development.

DSC1 DSC2

6.77e-041684229913133
Pubmed

RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.

DSC1 DSC2

6.77e-041684230689641
Pubmed

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels.

PIK3CA PECAM1

6.77e-041684225772358
Pubmed

Network organization of the human autophagy system.

DSC1 ERC1 FNIP1 MLST8 PRMT7 NEK9

6.77e-0443784620562859
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

BLM SMG1 USP15 TRRAP GTF3C4 LRCH3

7.01e-0444084634244565
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

FEM1B DSC1 SSU72 ACAD9 SIPA1L1 FBXW5 JOSD1 USP15 TRRAP

7.18e-04100584919615732
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PDIA6 COG7 PEPD RANBP6 CTPS1 PAPSS1 USP15 NEK9 GTF3C4 DDX1 CHUK

7.46e-041455841122863883
Pubmed

The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC.

GTF3C4 POLR3F

7.66e-04178421403646
Pubmed

Screening E3 substrates using a live phage display library.

DDX42 PDS5A

7.66e-041784224124579
Pubmed

Desmoplakin is essential in epidermal sheet formation.

DSC1 DSC2

7.66e-041784211781569
InteractionCD40 interactions

TRAF5 INTS2 PIK3CA COG7 MLST8 USP15 CHUK

3.24e-06153837int:CD40
GeneFamilyDesmosomal cadherins

DSC1 DSC2

2.40e-0476221188
GeneFamilyCadherin related

FAT1 CDHR4

1.52e-031762224
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 ARHGAP31 ERC1 PECAM1 MCF2L PREX2

1.83e-061948460b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP31 PECAM1 MCF2L PTCHD4 PREX2

2.51e-05183845c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

HMCN1 ARHGAP31 TLR7 ZNF518B PREX2

2.57e-0518484567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

2.71e-0518684577592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 LAMA3 PTCHD4 PREX2 MYO16

2.71e-05186845310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

ARHGAP31 PECAM1 MCF2L PTCHD4 PREX2

2.78e-05187845fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

2.85e-051888458268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 LAMA3 PTCHD4 PREX2 MYO16

2.85e-051888450501a8aa850bd2e347020abd1cac4d8075738189
ToppCellfacs-Lung|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HMCN1 ARHGAP31 PECAM1 ZSCAN26 PREX2

2.85e-05188845f7292fc8e914f222828dcdb0a017d716207a97f6
ToppCellfacs-Lung|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 ZSCAN26 PREX2

2.85e-05188845e2b6e14579ec649a2bc106d9c99bb78ceb16ede3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

2.85e-051888453139540a656c0436b2123ea50741ff8d00112165
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X LAMA3 PREX2

2.93e-051898456463890d8dbee4bc198f91628a5f784970de786a
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 LAMA3 PREX2

3.00e-051908459d5242759546be0089981ef1877e4ed5f81face5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.00e-051908452f54da2bee411f8868348a4c37034184b8f58a89
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.00e-051908453b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.00e-0519084556cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.00e-0519084559720dfe9de1b980807644536c919d2a02ba69dd
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 LAMA3 PREX2

3.00e-05190845b7fc451e160e31dc898b122de844b501f587db67
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.00e-0519084525d4b591f75c26e404a34c42f1742d580af6598d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.00e-05190845dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 LAMA3 PREX2

3.00e-0519084583cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 LAMA3 PREX2

3.00e-051908455f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 LAMA3 PTCHD4 PREX2 MYO16

3.08e-051918457b386512284dfaa0e95358b28ee82632ee965e64
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 LAMA3 PTCHD4 PREX2 MYO16

3.08e-05191845fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.16e-05192845f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.16e-05192845690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X LAMA3 PREX2

3.16e-0519284556b021c297a21dff357531f21e2464f85186106d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.23e-05193845294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 ARHGAP31 PECAM1 MCF2L PREX2

3.23e-051938456e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 ARHGAP31 ERC1 PECAM1 MCF2L

3.23e-05193845e1d546165dcc2392f540162206852c4717d7306f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.23e-051938453d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

HMCN1 ARHGAP31 PECAM1 MCF2L PREX2

3.23e-05193845e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.32e-0519484552aebb0b563e2c2058e7f0554ae870e47692b163
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.32e-051948456ac759828c41ffa974ee82842162caa959351dd1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.32e-051948455d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.32e-05194845bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X LAMA3 PREX2

3.40e-051958456bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

HMCN1 ARHGAP31 PECAM1 MCF2L PREX2

3.40e-05195845fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

HMCN1 ARHGAP31 PECAM1 MCF2L PREX2

3.40e-0519584519e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 ARHGAP31 PECAM1 OVCH1 PREX2

3.48e-05196845e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 ARHGAP31 PECAM1 MCF2L PREX2

3.57e-0519784587eda06344498dc66cac292cf89746dc90b5cf67
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

HMCN1 ARHGAP31 PECAM1 MCF2L PREX2

3.57e-05197845ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

HMCN1 ARHGAP31 PECAM1 MCF2L PREX2

3.57e-05197845f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 SMG1 ABCA5 NLRC5 USP15

3.74e-05199845f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.83e-05200845ca5401b76ab014080914bf78042d368cf318effa
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HMCN1 PECAM1 ZNF518B MCF2L PREX2

3.83e-05200845dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 LAMA3 PTCHD4 PREX2 MYO16

3.83e-05200845862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.83e-0520084570c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.83e-05200845e90155498397524b812c46f2412320230b445bb6
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 LAMA3 PTCHD4 PREX2 MYO16

3.83e-05200845a91345f268f13170c27309333603eb82400c9947
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 ARHGAP31 PTCHD4 PREX2 MYO16

3.83e-0520084540286010bd17cf9e34ecd5440953b072ebfae208
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 LAMA3 PTCHD4 PREX2 MYO16

3.83e-05200845d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FEM1B CACNA1A TRAF5 ACHE CTPS1

3.83e-05200845a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A PCDH11X TLR7 LRCH3

1.24e-041358449f9d0787a2e99207a9caa88a85565189ab8b940a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP31 ZSCAN26 HRG CHUK

1.55e-041438448f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X PREX2

1.86e-04150844322aa0c3fc159a4b2897daac881dfc744b24ffc4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X LAMA3

2.06e-04154844e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCellfacs-Aorta-Heart-24m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL2L14 NDUFAF7 CDK5RAP1 PRMT7

2.33e-04159844443f6df4a88fa8755adcde4cc12575dff614ecb4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X PREX2

2.68e-04165844a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 HMCN1 GDAP1 GTSF1L

2.68e-041658446d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GOT1L1 HMCN1 GDAP1 GTSF1L

2.68e-0416584484f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BLM ARHGAP31 PECAM1 LAMA3

2.74e-041668448e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PIK3CA ACHE PTCHD4 MYO16

2.93e-04169844c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X PREX2

2.93e-04169844c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BLM ARHGAP31 PECAM1 PREX2

3.14e-04172844c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BLM CASD1 ZSCAN26 GTF3C4

3.21e-04173844efb8072475000888efe088d00e870c56ffad4172
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PRDM12 PREX2

3.42e-04176844dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 PECAM1 PCDH11X PREX2

3.57e-041788445f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-4|TCGA-Breast / Sample_Type by Project: Shred V9

DSC2 JOSD1 CTPS1 PAPSS1

3.57e-0417884444b5ba4e8788d3973749a1717e427647ac4c8579
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

BCL2L14 MTHFSD ACHE ABCD2

3.65e-041798445f7e6670a0e906a0a5bc75735408361d88e78fa2
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNA1A FAT1 TRAF5 LAMA3

3.65e-04179844a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

BCL2L14 ARHGAP31 PECAM1 PREX2

3.65e-041798442a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP31 PECAM1 PCDH11X PREX2

3.88e-041828440639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP31 PECAM1 MCF2L PREX2

3.88e-0418284481279877b920b5a1bc991a07d3031d6458700fe3
ToppCellP28-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HMCN1 ARHGAP31 PECAM1 MCF2L

3.88e-04182844db5d6c5e7d59734653906b126f2c1d57461a5290
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 PREX2

3.88e-041828443b4dbf61ca0fe50efe05449815630e301cb76630
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 PREX2

3.88e-04182844ab5761bf9af439231cd0f487b6467e372672a517
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 PREX2

3.96e-04183844c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 ARHGAP31 PECAM1 PREX2

3.96e-04183844dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 ARHGAP31 PECAM1 PREX2

3.96e-041838444759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

BCL2L14 DSC2 ACHE GTSF1L

3.96e-04183844bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 PREX2

3.96e-04183844c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 ZSCAN26

3.96e-041838441e51aeaa8fc9383b424cce128a890e07cb6025f3
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP31 PECAM1 MCF2L PREX2

3.96e-04183844ff95382cfed592190d0636d2b750328471f82e0d
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 PREX2

3.96e-0418384492eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP31 PECAM1 MCF2L PREX2

4.05e-04184844fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 HMCN1 PCDH11X MYO16

4.05e-041848442cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP31 ERC1 PECAM1 USP15

4.05e-04184844c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ARHGAP31 PREX2 MYO16

4.05e-04184844e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP31 PECAM1 MCF2L PREX2

4.05e-04184844ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP31 PTCHD4 PREX2 MYO16

4.05e-04184844ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 HMCN1 PCDH11X MYO16

4.05e-04184844ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 HMCN1 PCDH11X MYO16

4.05e-041848442b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP31 PECAM1 MCF2L PREX2

4.05e-041848441d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP31 PECAM1 MCF2L PREX2

4.05e-0418484476caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP31 PECAM1 MCF2L PREX2

4.05e-041848441fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP31 PECAM1 MCF2L PREX2

4.05e-041848442467207aaea307873ab286f89cfc7668a227a694
ToppCellControl-CD8+_T_activated|Control / Disease group and Cell class

ACAD9 MLST8 TCTN1 POLR3F

4.05e-04184844b86cc48b744b3206880ec1373fe6068e14bf9680
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ARHGAP31 PECAM1 PREX2

4.22e-041868440ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA6 ZSCAN26 GALNT12 MCF2L

4.22e-0418684432d30f08b20a0a28e38b37bd52ab26d1d43736ce
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1E

2.23e-053812DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1E

4.45e-054812DOID:6364 (implicated_via_orthology)
DiseaseOrganothiophosphate Poisoning

ACHE PEPD

4.45e-054812C3494248
DiseaseOrganothiophosphonate Poisoning

ACHE PEPD

4.45e-054812C3494247
DiseaseOrganophosphate poisoning

ACHE PEPD

4.45e-054812C0700359
DiseaseOrganophosphorus Poisoning

ACHE PEPD

4.45e-054812C0353676
DiseaseSkin Ulcer

PEPD LAMA3

4.45e-054812C0037299
Diseasearrhythmogenic right ventricular cardiomyopathy (implicated_via_orthology)

DSC1 DSC2

7.40e-055812DOID:0050431 (implicated_via_orthology)
Diseasedesmocollin-2 measurement

DSC1 DSC2

7.40e-055812EFO_0021936
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1E

1.55e-047812DOID:0050951 (implicated_via_orthology)
DiseaseColorectal Neoplasms

FAT1 ABCA5 PIK3CA GALNT12 ABCD2

1.01e-03277815C0009404
Diseaseantiphospholipid antibody measurement

CACNA1E MYO16

2.14e-0325812EFO_0005200
Diseasechronic myeloid leukemia (is_marker_for)

PECAM1 USP15

2.50e-0327812DOID:8552 (is_marker_for)
Diseaselung small cell carcinoma (is_implicated_in)

FAT1 LAMA3

2.69e-0328812DOID:5409 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
CPQLDIHFDVLTVEE

ABCA5

561

Q8WWZ7
DVVGDHNVVCPVAQL

ACHE

431

P22303
NCIVLALEQHLPDDD

CACNA1A

111

O00555
CIAVVEHELPNTDVT

BDP1

1936

A6H8Y1
AVPLEHGEVIDCVQE

COG7

376

P83436
EENDQLPLVHCVVAR

CATSPER4

336

Q7RTX7
ANCIVLALEQHLPED

CACNA1E

101

Q15878
VIDVDHGIICENVPI

ABCD2

471

Q9UBJ2
DILLNVVEQIPHGCV

GOT1L1

166

Q8NHS2
CEVHFENTKIPVENI

ACAD9

271

Q9H845
DVPVDVLEDICHQIL

CCNK

241

O75909
QPHIFNAVVEEICDS

ABHD4

326

Q8TB40
NVEQCLEHEAVDPKV

BCL2L14

136

Q9BZR8
ITIEVEDVNDHAPEC

CDHR4

536

A6H8M9
CIINIDDVNDHLPTF

DSC2

341

Q02487
ALVIHPEEDVQIQAC

ARMC12

296

Q5T9G4
QIADHCPDILEQVVN

ERC1

1096

Q8IUD2
VNNTILHPEIVECRV

PEPD

171

P12955
HEIITPEQFQLCALV

PDS5A

906

Q29RF7
ECSIHVEVIVDRPLQ

PCDHA2

101

Q9Y5H9
HIEQANECAPVITAV

FAT1

246

Q14517
CDVVLVADEQRVPAH

KLHL36

46

Q8N4N3
EIPIEACHFVSLENL

LRCH3

96

Q96II8
NLVINCEVFDPQEHE

HRG

236

P04196
LHQVCIIPIEEFSAE

LAMA3

1031

Q16787
PVEQVSCGDNHVVVL

NEK9

481

Q8TD19
INEVLFLHEQVECVQ

MYO16

806

Q9Y6X6
VPIKNLEEHEAVCVN

GTSF1L

51

Q9H1H1
ACDVPEELNILIHDV

CHUK

76

O15111
DAVLGQPIHECREVI

KIAA2026

446

Q5HYC2
CEVLQKISEAEAVHP

MLYCD

206

O95822
IHLNETVKAPDIECV

FEM1B

396

Q9UK73
GELTPHQCVEVENIV

FSIP2

6136

Q5CZC0
EIEEHLNCTISQVEP

DDX1

661

Q92499
IVCPTRELCQQIHAE

DDX42

331

Q86XP3
INCVCLHPNQAELIV

MLST8

131

Q9BVC4
PCVEVQTLREHTDQV

FBXW5

81

Q969U6
CTIQVTHLAQEFPEI

PECAM1

256

P16284
EVPVLIHGENIICEA

GDAP1

76

Q8TB36
PDVQLCHCIERTVIE

INTS2

1181

Q9H0H0
NCELLLVVPEEVEAH

JOSD1

181

Q15040
VIAPEHVDICKNNNL

PRDM12

121

Q9H4Q4
HIIQELPLDNTFVAC

PCDH11X

961

Q9BZA7
INHDCVPEQVIAEAI

PIK3CA

211

P42336
QEENPEAVALRLAHC

NLRC5

1431

Q86WI3
VAVVVNNPVRLECEA

HMCN1

2021

Q96RW7
VFVDAPLHVCEQRDV

PAPSS1

156

O43252
ICIDDGPIAEVHINE

BLM

236

P54132
ECNELHPSVSVVQIL

CASD1

666

Q96PB1
LVEENCEAVPHRATV

PRMT7

166

Q9NVM4
QHPVLDEPIAEAVCI

FNIP1

1036

Q8TF40
HEEESAVVCPVIDVI

GALNT12

246

Q8IXK2
HQDIVPLCAADIQDQ

MCF2L

61

O15068
NDHAPQIDKEVTICQ

DSC1

571

Q08554
CEEHQLCVVAVLPHI

PDIA6

291

Q15084
HVEVCPDAGVIIEEL

NDUFAF7

271

Q7L592
VEHLSIISQPCLVED

IQCA1L

246

A6NCM1
LQQIQVHVLEREVCE

OVCH1

716

Q7RTY7
IECIEIQENPDHVTT

PTCHD4

831

Q6ZW05
VVEALCELHCPEAIQ

SMG1

1076

Q96Q15
VEPEQVICVHDVSSI

CTPS1

236

P17812
KEVLEHVVPELNVQC

SIPA1L1

571

O43166
VCVAQDPEQLHLKAQ

SPATA31E1

1081

Q6ZUB1
VEIENRIIELCHQFP

POLR3F

16

Q9H1D9
DQCIQDQEHPAIRTL

RANBP6

186

O60518
VVINLQNHEENLCPE

TRAF5

176

O00463
PDEVLQLIHERDNIC

CDK5RAP1

381

Q96SZ6
GTHVCPVRVQQEIDD

CYP2D7

341

A0A087X1C5
PEVCQVDEQIERQHQ

ZNF182

96

P17025
PEVELEHQQCLAVFS

NAA35

221

Q5VZE5
VCAAVSREPDILVHQ

TKTL2

576

Q9H0I9
VESQHPENCQEVVAL

ZNF274

221

Q96GC6
VHDCQVVDIPEELVE

MTHFSD

181

Q2M296
ELVDQINPSIFCIHI

TCTN1

141

Q2MV58
INRTEDTEHVIIPVC

USP15

556

Q9Y4E8
VEECLHPEPNAQQEV

PREX2

91

Q70Z35
HCPEEGQLARIQNVI

ARHGAP31

121

Q2M1Z3
IAVLELICDVHNPGQ

GTF3C4

86

Q9UKN8
CDVTLDVPKNHVIVD

TLR7

36

Q9NYK1
QEQQVRHECEVTKPE

ZSCAN26

161

Q16670
CHVPDVELLQDVRNV

TRIM64

236

A6NGJ6
LAICHPEEQQLSFIE

TRRAP

2891

Q9Y4A5
REQETCQPVHVVNVD

SSU72

126

Q9NP77
IVNLQEECSPHLEDV

ZNF285

91

Q96NJ3
ELVVPANCLAQLIDV

ZNF518B

336

Q9C0D4