Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N-acetyllactosamine synthase activity	B4GALT5 B4GALT3	2.48e-05	5	32	2	GO:0003945
GeneOntologyMolecularFunction	tRNA pseudouridine synthase activity	PUSL1 PUS3	6.92e-05	8	32	2	GO:0106029
GeneOntologyMolecularFunction	pseudouridine synthase activity	PUSL1 PUS3	1.92e-04	13	32	2	GO:0009982
GeneOntologyMolecularFunction	intramolecular transferase activity	PUSL1 PUS3	9.83e-04	29	32	2	GO:0016866
GeneOntologyMolecularFunction	UDP-galactosyltransferase activity	B4GALT5 B4GALT3	1.20e-03	32	32	2	GO:0035250
GeneOntologyMolecularFunction	galactosyltransferase activity	B4GALT5 B4GALT3	1.43e-03	35	32	2	GO:0008378
GeneOntologyBiologicalProcess	tRNA pseudouridine synthesis	PUSL1 PUS3	3.71e-05	6	33	2	GO:0031119
Domain	LCE	LCE2D LCE2C LCE2B	3.06e-06	17	32	3	PF14672
Domain	LCE	LCE2D LCE2C LCE2B	3.06e-06	17	32	3	IPR028205
Domain	PsdUridine_synth_TruA_N	PUSL1 PUS3	8.52e-06	3	32	2	IPR020094
Domain	PsdUridine_synth_TruA_C	PUSL1 PUS3	8.52e-06	3	32	2	IPR020095
Domain	PsdUridine_synth_TruA_a/b_dom	PUSL1 PUS3	8.52e-06	3	32	2	IPR020097
Domain	-	PUSL1 PUS3	8.52e-06	3	32	2	3.30.70.580
Domain	PsdUridine_synth_TruA	PUSL1 PUS3	8.52e-06	3	32	2	IPR001406
Domain	PseudoU_synth_1	PUSL1 PUS3	8.52e-06	3	32	2	PF01416
Domain	-	PUSL1 PUS3	8.52e-06	3	32	2	3.30.70.660
Domain	SPRR/LCE	LCE2D LCE2C LCE2B	1.45e-05	28	32	3	IPR026075
Domain	Galactosyl_T	B4GALT5 B4GALT3	5.94e-05	7	32	2	IPR003859
Domain	Galactosyl_T_C	B4GALT5 B4GALT3	5.94e-05	7	32	2	IPR027791
Domain	Galactosyl_T_N	B4GALT5 B4GALT3	5.94e-05	7	32	2	IPR027995
Domain	Glyco_transf_7C	B4GALT5 B4GALT3	5.94e-05	7	32	2	PF02709
Domain	Glyco_transf_7N	B4GALT5 B4GALT3	5.94e-05	7	32	2	PF13733
Domain	SCAN	ZNF444 ZSCAN10 ZSCAN4	1.19e-04	56	32	3	SM00431
Domain	SCAN_BOX	ZNF444 ZSCAN10 ZSCAN4	1.32e-04	58	32	3	PS50804
Domain	SCAN	ZNF444 ZSCAN10 ZSCAN4	1.32e-04	58	32	3	PF02023
Domain	SCAN_dom	ZNF444 ZSCAN10 ZSCAN4	1.32e-04	58	32	3	IPR003309
Domain	Retrov_capsid_C	ZNF444 ZSCAN10 ZSCAN4	1.39e-04	59	32	3	IPR008916
Domain	PsdUridine_synth_cat_dom	PUSL1 PUS3	2.19e-04	13	32	2	IPR020103
Domain	-	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	5.58e-03	679	32	5	3.30.160.60
Domain	zf-C2H2	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	6.08e-03	693	32	5	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	6.12e-03	694	32	5	IPR013087
Domain	-	B4GALT5 B4GALT3	8.47e-03	81	32	2	3.90.550.10
Domain	ZINC_FINGER_C2H2_2	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	9.64e-03	775	32	5	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	9.74e-03	777	32	5	PS00028
Domain	Nucleotide-diphossugar_trans	B4GALT5 B4GALT3	9.93e-03	88	32	2	IPR029044
Domain	Znf_C2H2-like	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	1.07e-02	796	32	5	IPR015880
Domain	Znf_C2H2	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	1.12e-02	805	32	5	IPR007087
Domain	ZnF_C2H2	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	1.14e-02	808	32	5	SM00355
Domain	zf-C2H2_6	ZNF320 ZSCAN10 ZNF574	1.63e-02	314	32	3	PF13912
Pubmed	Rodent Lce gene clusters; new nomenclature, gene organization, and divergence of human and rodent genes.	LCE2D LCE2C LCE2B	4.32e-07	16	33	3	17410201
Pubmed	Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation.	LCE2D LCE2C LCE2B	1.18e-06	22	33	3	15854049
Pubmed	Differentially expressed late constituents of the epidermal cornified envelope.	LCE2D LCE2C LCE2B	1.36e-06	23	33	3	11698679
Pubmed	Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development.	B4GALT5 B4GALT3	5.23e-06	4	33	2	11145975
Pubmed	Zfp206 regulates ES cell gene expression and differentiation.	ZSCAN10 ZSCAN4	5.23e-06	4	33	2	16971461
Pubmed	The expanding beta 4-galactosyltransferase gene family: messages from the databanks.	B4GALT5 B4GALT3	1.31e-05	6	33	2	9597550
Pubmed	Protein-protein interaction panel using mouse full-length cDNAs.	KCTD13 LCE2D LCE2C LCE2B	1.63e-05	161	33	4	11591653
Pubmed	Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.	B4GALT5 B4GALT3	1.04e-04	16	33	2	10580128
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GRAMD1B CACNA1B KCTD13 CIT HDLBP ATG2B	6.32e-04	1139	33	6	36417873
Interaction	KRTAP10-7 interactions	ZNF444 ZNF320 ZSCAN10 LCE2D LCE2C LCE2B	7.14e-06	293	33	6	int:KRTAP10-7
Interaction	SLC39A7 interactions	KCTD13 CIT LCE2D LCE2C B4GALT3	1.25e-05	187	33	5	int:SLC39A7
Interaction	RGS20 interactions	ZNF444 LCE2D LCE2C LCE2B	4.01e-05	118	33	4	int:RGS20
Interaction	KRTAP1-5 interactions	LCE2D LCE2C LCE2B	6.58e-05	48	33	3	int:KRTAP1-5
Interaction	KRTAP17-1 interactions	LCE2D LCE2C LCE2B	6.58e-05	48	33	3	int:KRTAP17-1
Interaction	UPF3B interactions	UPF3A KCTD13 CIT HDLBP	6.97e-05	136	33	4	int:UPF3B
Interaction	SLC4A10 interactions	KCTD13 CIT	1.16e-04	10	33	2	int:SLC4A10
Interaction	KRTAP10-5 interactions	ZNF320 LCE2D LCE2C LCE2B	1.31e-04	160	33	4	int:KRTAP10-5
Interaction	KRTAP5-2 interactions	LCE2D LCE2C LCE2B	1.42e-04	62	33	3	int:KRTAP5-2
Interaction	RBMXL3 interactions	CIT HDLBP	1.42e-04	11	33	2	int:RBMXL3
Interaction	KRTAP5-4 interactions	LCE2D LCE2C LCE2B	1.49e-04	63	33	3	int:KRTAP5-4
Interaction	KRTAP5-3 interactions	LCE2D LCE2C LCE2B	1.71e-04	66	33	3	int:KRTAP5-3
Interaction	LCE1E interactions	LCE2D LCE2C LCE2B	1.86e-04	68	33	3	int:LCE1E
Interaction	LCE2A interactions	LCE2D LCE2C LCE2B	1.95e-04	69	33	3	int:LCE2A
Interaction	LCE1D interactions	LCE2D LCE2C LCE2B	2.03e-04	70	33	3	int:LCE1D
Interaction	KRTAP5-7 interactions	LCE2D LCE2C LCE2B	2.12e-04	71	33	3	int:KRTAP5-7
Interaction	LCE3D interactions	LCE2D LCE2C LCE2B	2.30e-04	73	33	3	int:LCE3D
Interaction	LCE2D interactions	LCE2D LCE2C LCE2B	2.40e-04	74	33	3	int:LCE2D
Interaction	KRTAP4-5 interactions	LCE2D LCE2C LCE2B	2.59e-04	76	33	3	int:KRTAP4-5
Interaction	LCE3A interactions	LCE2D LCE2C LCE2B	2.59e-04	76	33	3	int:LCE3A
Interaction	CORO1B interactions	ITGA2B KCTD13 CIT HDLBP	2.63e-04	192	33	4	int:CORO1B
Interaction	LCE1C interactions	LCE2D LCE2C LCE2B	2.69e-04	77	33	3	int:LCE1C
Interaction	CRP interactions	VGF B4GALT5 B4GALT3	2.69e-04	77	33	3	int:CRP
Interaction	LCE4A interactions	LCE2D LCE2C LCE2B	3.02e-04	80	33	3	int:LCE4A
Interaction	MAP2K4 interactions	PUS3 KCTD13 HDLBP	3.13e-04	81	33	3	int:MAP2K4
Interaction	KRTAP4-4 interactions	LCE2D LCE2C LCE2B	3.13e-04	81	33	3	int:KRTAP4-4
Interaction	LCE2B interactions	LCE2D LCE2C LCE2B	3.13e-04	81	33	3	int:LCE2B
Interaction	KRTAP5-9 interactions	ADAMTSL5 LCE2D LCE2C LCE2B	3.25e-04	203	33	4	int:KRTAP5-9
Interaction	LCE1A interactions	LCE2D LCE2C LCE2B	3.48e-04	84	33	3	int:LCE1A
Interaction	LCE1B interactions	LCE2D LCE2C LCE2B	3.61e-04	85	33	3	int:LCE1B
Interaction	LTBP2 interactions	ZNF444 ZNF320 ZNF574	3.61e-04	85	33	3	int:LTBP2
Interaction	LCE2C interactions	LCE2D LCE2C LCE2B	3.99e-04	88	33	3	int:LCE2C
Interaction	KRTAP10-6 interactions	LCE2D LCE2C LCE2B	3.99e-04	88	33	3	int:KRTAP10-6
Interaction	ARPC1B interactions	ITGA2B KCTD13 CIT ASH1L	4.04e-04	215	33	4	int:ARPC1B
Interaction	ADAMTSL4 interactions	ADAMTSL5 LCE2D LCE2C LCE2B	4.19e-04	217	33	4	int:ADAMTSL4
Interaction	LCE5A interactions	LCE2D LCE2C LCE2B	4.26e-04	90	33	3	int:LCE5A
Interaction	GRAMD1C interactions	GRAMD1B CIT	4.37e-04	19	33	2	int:GRAMD1C
Interaction	LCE1F interactions	LCE2D LCE2C LCE2B	4.55e-04	92	33	3	int:LCE1F
Interaction	KRTAP4-11 interactions	LCE2D LCE2C LCE2B	4.55e-04	92	33	3	int:KRTAP4-11
Interaction	GPI interactions	ITGA2B KCTD13 CIT HDLBP	4.56e-04	222	33	4	int:GPI
Interaction	KRTAP5-6 interactions	LCE2D LCE2C LCE2B	4.84e-04	94	33	3	int:KRTAP5-6
Interaction	KRTAP2-3 interactions	LCE2D LCE2C LCE2B	5.00e-04	95	33	3	int:KRTAP2-3
Interaction	NUFIP2 interactions	KCTD13 CIT LCE2D LCE2C LCE2B	5.45e-04	417	33	5	int:NUFIP2
Interaction	KRTAP9-8 interactions	LCE2D LCE2C LCE2B	5.80e-04	100	33	3	int:KRTAP9-8
Cytoband	16q21	BEAN1 NOD2	4.87e-04	45	33	2	16q21
Cytoband	9q34	NELFB CACNA1B	7.00e-04	54	33	2	9q34
Cytoband	19q13.43	ZNF444 ZSCAN4	1.80e-03	87	33	2	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	LCE2D LCE2C LCE2B	3.03e-03	404	33	3	chr1q21
Cytoband	1q21.3	LCE2D LCE2C	3.23e-03	117	33	2	1q21.3
Cytoband	16p11.2	KCTD13 SLC5A2	8.35e-03	191	33	2	16p11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	GRAMD1B PUS3	8.35e-03	191	33	2	chr11q24
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF444 ZNF320 ZSCAN4 ZNF574	1.02e-02	1192	33	4	chr19q13
GeneFamily	Late cornified envelope proteins	LCE2D LCE2C LCE2B	1.45e-06	18	23	3	627
GeneFamily	Beta 4-glycosyltransferases	B4GALT5 B4GALT3	2.08e-04	17	23	2	425
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF444 ZNF320 ZSCAN10 ZSCAN4 ZNF574	1.81e-03	718	23	5	28
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM156A VGF FAM135B B4GALT5	4.62e-06	151	33	4	b545823113a3450c5f841f7de48bf0937593544f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM156A VGF FAM135B B4GALT5	4.62e-06	151	33	4	0cc2f4aec3dae4603fa831f22c40f897e68b34e2
Disease	Parkinson disease	CACNA1B FANCF ITGA2B ASH1L NOD2	8.05e-06	321	26	5	MONDO_0005180
Disease	multiple sclerosis (is_marker_for)	CACNA1B B4GALT5	8.56e-04	49	26	2	DOID:2377 (is_marker_for)
Disease	QRS-T angle	KCTD13 FAM135B	3.93e-03	106	26	2	EFO_0020097
Disease	chronic lymphocytic leukemia	GRAMD1B HDLBP	4.92e-03	119	26	2	EFO_0000095
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	ITGA2B B4GALT5	5.93e-03	131	26	2	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	ITGA2B B4GALT5	5.93e-03	131	26	2	C4552091
Disease	Juvenile arthritis	ITGA2B B4GALT5	5.93e-03	131	26	2	C3495559
Disease	Juvenile psoriatic arthritis	ITGA2B B4GALT5	5.93e-03	131	26	2	C3714758
Disease	Global developmental delay	CACNA1B PUS3	6.11e-03	133	26	2	C0557874
Disease	Juvenile-Onset Still Disease	ITGA2B B4GALT5	6.28e-03	135	26	2	C0087031
Disease	Intellectual Disability	CACNA1B PUS3 ASH1L	6.93e-03	447	26	3	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
RRIHVRRHITHDERP	KCTD13	306	Q8WZ19
AIIVPHRAREHHLRL	B4GALT3	126	O60512
IRITHRSHHFIPRDL	ASH1L	1301	Q9NR48
NEDVRPHIRDRFRLH	CTDSPL2	446	Q05D32
RNRHEHLPVLFRHLL	B4GALT5	171	O43286
EAAEREPRRHRAHRH	CACNA1B	926	Q00975
RRLKERMHHNIPHRF	CIT	1351	O14578
RFPHHRLAHQPVDLR	ATG2B	1976	Q96BY7
VRRRKRPHAHLRVPH	GRAMD1B	561	Q3KR37
LRHVRRRHRDHMAPY	FAM156A	91	Q8NDB6
LRHIHRRFGRHGPIR	FANCF	41	Q9NPI8
HRHALRLLIHLHPRV	NELFB	501	Q8WX92
ARHIRVEHRSRNHLA	ADAMTSL5	226	Q6ZMM2
LVPETHRRVRLHRHG	PARD6G	151	Q9BYG4
QERHRRHHVRCHAAP	C7orf61	176	Q8IZ16
HRPRLFHRRRHQSPD	LCE2B	76	O14633
HRPRLFHRRRHQSPD	LCE2C	76	Q5TA81
HRPRLFHRRRHQSPD	LCE2D	76	Q5TA82
REVLHPFVRRHALHR	FAM135B	711	Q49AJ0
RDRQARLQRHRHRHH	BEAN1	61	Q3B7T3
HLRHPAIRVLRAFRV	PUSL1	101	Q8N0Z8
RIQHFVRRGRIEHPH	PUS3	426	Q9BZE2
LRRRHYHHALPPSRH	VGF	561	O15240
GRRHRAHHEPERLSR	UPF3A	366	Q9H1J1
HPAHHKRDRRQIFLP	ITGA2B	881	P08514
FRRKEHLRRHRDTHP	ZNF444	216	Q8N0Y2
FRRSEHLVAHRRVHT	ZSCAN10	476	Q96SZ4
RNAHLRRHLATHAEP	ZSCAN10	646	Q96SZ4
ESRFHLHLRRHRRIH	ZNF320	141	A2RRD8
SHRPAIVRRLHSHVE	NOD2	136	Q9HC29
IPRKHLHRLVFSLRH	SLC5A2	551	P31639
LTRHQRFVHRLERRH	ZNF574	481	Q6ZN55
HAFLRHVPLRRIHLF	SLC4A5	1006	Q9BY07
HLLAHQRRHRNERPF	ZSCAN4	326	Q8NAM6
HHRHFVIRRGQVLRE	HDLBP	811	Q00341