Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintegrin binding

ADAM18 ITGA1 PTPRZ1 CD40LG DMD TNR UTRN CDH17

1.46e-051751258GO:0005178
GeneOntologyMolecularFunctioncell adhesion molecule binding

DSG2 ADAM18 NTNG1 ITGA1 NECTIN3 DDX3X ASAP1 PTPRO PTPRZ1 CD40LG DMD TNR UTRN CDH17

2.36e-0559912514GO:0050839
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH17 DNAH11

1.82e-04181253GO:0008569
GeneOntologyCellularComponentsynaptic membrane

CACNA2D1 IL31RA ANK1 NTNG1 HTR3C NECTIN3 CHRNE MET NTNG2 SYNJ1 PTPRO PTPRZ1 ANO6 FARP1 DMD UTRN GABRA4

8.19e-0858312617GO:0097060
GeneOntologyCellularComponentactin-based cell projection

ATP6V1A IQGAP2 LOXHD1 PTPRZ1 FARP1 SYNE2 PTPRQ DMD USH2A UTRN EXOC4

9.93e-0727812611GO:0098858
GeneOntologyCellularComponentpostsynaptic membrane

CACNA2D1 ANK1 HTR3C NECTIN3 CHRNE MET PTPRO PTPRZ1 FARP1 DMD UTRN GABRA4

6.34e-0640512612GO:0045211
GeneOntologyCellularComponentgerm plasm

TDRD9 PIWIL2 DDX3X DDX3Y

2.66e-05291264GO:0060293
GeneOntologyCellularComponentpole plasm

TDRD9 PIWIL2 DDX3X DDX3Y

2.66e-05291264GO:0045495
GeneOntologyCellularComponentP granule

TDRD9 PIWIL2 DDX3X DDX3Y

2.66e-05291264GO:0043186
GeneOntologyCellularComponentsomatodendritic compartment

EPHB3 SRR ITGA1 NECTIN3 ASAP1 MET ERCC8 SNX14 TRPM5 HMCN2 PTPRO PTPRZ1 FARP1 DMD USH2A NOS1 IL6ST FCHSD1 EXOC4 GABRA4

4.50e-05122812620GO:0036477
GeneOntologyCellularComponentcell leading edge

ANK1 IQGAP2 DDX3X ARAP3 PTPRO PTPRZ1 SYNE2 FGD1 DMD USH2A EXOC4 GABRA4

5.07e-0550012612GO:0031252
GeneOntologyCellularComponentlamellipodium

IQGAP2 DDX3X ARAP3 PTPRO PTPRZ1 SYNE2 FGD1 DMD

7.84e-052301268GO:0030027
GeneOntologyCellularComponentfilopodium

IQGAP2 PTPRZ1 FARP1 SYNE2 DMD UTRN

1.02e-041231266GO:0030175
GeneOntologyCellularComponentsarcolemma

CACNA2D1 ANK1 CAPN3 DMD NOS1 UTRN AHNAK2

1.56e-041901267GO:0042383
GeneOntologyCellularComponentfilopodium membrane

SYNE2 DMD UTRN

2.63e-04211263GO:0031527
GeneOntologyCellularComponentZ disc

ANK1 CAPN3 SYNE2 DMD NOS1 AHNAK2

3.11e-041511266GO:0030018
GeneOntologyCellularComponentpostsynapse

CACNA2D1 ANK1 HTR3C NECTIN3 ASAP1 CHRNE MET SNX14 PTPRO PTPRZ1 FARP1 DMD NOS1 UTRN EXOC4 GABRA4

4.14e-04101812616GO:0098794
GeneOntologyCellularComponentI band

ANK1 CAPN3 SYNE2 DMD NOS1 AHNAK2

5.14e-041661266GO:0031674
GeneOntologyCellularComponentcell surface

IL31RA IQGAP2 DSG2 ITGA1 PTGFRN ADGRG6 MET ANO6 CD40LG ULBP1 DMD SLITRK6 LY9 TNR IL6ST CDH17

1.06e-03111112616GO:0009986
GeneOntologyCellularComponentT-tubule

CACNA2D1 CAPN3 NOS1 AHNAK2

1.33e-03791264GO:0030315
GeneOntologyCellularComponentperineuronal net

PTPRZ1 TNR

1.57e-03101262GO:0072534
GeneOntologyCellularComponentmembrane protein complex

ATP6V1A CACNA2D1 ANK1 PKD1L1 HTR3C ITGA1 CHRNE TRPM5 SYNJ1 PIK3C2A ANO6 SYNE2 AGK DMD ATP1A4 UTRN IL6ST CDH17 GABRA4

1.59e-03149812619GO:0098796
GeneOntologyCellularComponentperisynaptic extracellular matrix

PTPRZ1 TNR

1.91e-03111262GO:0098966
GeneOntologyCellularComponentsarcoplasmic reticulum

CACNA2D1 ANK1 SYNE2 NOS1

1.99e-03881264GO:0016529
GeneOntologyCellularComponentdendrite

EPHB3 NECTIN3 ASAP1 MET SNX14 TRPM5 PTPRO PTPRZ1 FARP1 NOS1 IL6ST EXOC4 GABRA4

2.04e-0385812613GO:0030425
GeneOntologyCellularComponentdendritic tree

EPHB3 NECTIN3 ASAP1 MET SNX14 TRPM5 PTPRO PTPRZ1 FARP1 NOS1 IL6ST EXOC4 GABRA4

2.08e-0386012613GO:0097447
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

NTNG1 NTNG2 SYNJ1 TNR EXOC4

2.50e-031551265GO:0098685
GeneOntologyCellularComponentsynapse-associated extracellular matrix

PTPRZ1 TNR

2.69e-03131262GO:0099535
Domainfn3

EPHB3 IL31RA PTPRO PTPRZ1 TNR USH2A SDK1 IL6ST

1.34e-051621258PF00041
DomainFN3

EPHB3 IL31RA PTPRO PTPRZ1 TNR USH2A SDK1 IL6ST

3.49e-051851258SM00060
DomainDystrophin

DMD UTRN

4.44e-0521252IPR016344
DomainFN3

EPHB3 IL31RA PTPRO PTPRZ1 TNR USH2A SDK1 IL6ST

5.85e-051991258PS50853
DomainFN3_dom

EPHB3 IL31RA PTPRO PTPRZ1 TNR USH2A SDK1 IL6ST

8.25e-052091258IPR003961
DomainLaminin_N

NTNG1 NTNG2 USH2A

1.54e-04161253IPR008211
DomainLamNT

NTNG1 NTNG2 USH2A

1.54e-04161253SM00136
DomainLAMININ_NTER

NTNG1 NTNG2 USH2A

1.54e-04161253PS51117
DomainLaminin_N

NTNG1 NTNG2 USH2A

1.54e-04161253PF00055
DomainIg-like_fold

EPHB3 IL31RA NECTIN3 IL1RL2 PTGFRN MET HMCN2 PTPRO PTPRZ1 LY9 TNR USH2A SDK1 IL6ST

2.72e-0470612514IPR013783
DomainEGF_1

ADAM18 NTNG1 MUC12 ADAM32 NTNG2 HMCN2 TNR USH2A

3.22e-042551258PS00022
DomainWW_DOMAIN_1

IQGAP2 ARHGAP12 DMD UTRN

3.75e-04511254PS01159
DomainWW_DOMAIN_2

IQGAP2 ARHGAP12 DMD UTRN

3.75e-04511254PS50020
DomainWW_dom

IQGAP2 ARHGAP12 DMD UTRN

4.04e-04521254IPR001202
DomainDUF1785

PIWIL2 AGO4

4.39e-0451252SM01163
DomainSpectrin

SYNE2 DMD UTRN

4.70e-04231253PF00435
DomainACTININ_2

SYNE2 DMD UTRN

4.70e-04231253PS00020
DomainACTININ_1

SYNE2 DMD UTRN

4.70e-04231253PS00019
DomainActinin_actin-bd_CS

SYNE2 DMD UTRN

4.70e-04231253IPR001589
Domain-

EPHB3 IL31RA NECTIN3 IL1RL2 PTGFRN MET PTPRO PTPRZ1 LY9 TNR USH2A SDK1 IL6ST

5.04e-04663125132.60.40.10
DomainPH

ARHGEF12 ASAP1 ARAP3 SBF1 FARP1 ARHGAP12 OSBPL8 FGD1

5.71e-042781258SM00233
DomainPH_DOMAIN

ARHGEF12 ASAP1 ARAP3 SBF1 FARP1 ARHGAP12 OSBPL8 FGD1

5.84e-042791258PS50003
DomainPH_domain

ARHGEF12 ASAP1 ARAP3 SBF1 FARP1 ARHGAP12 OSBPL8 FGD1

5.98e-042801258IPR001849
DomainArgoL1

PIWIL2 AGO4

6.55e-0461252PF08699
DomainArgoL1

PIWIL2 AGO4

6.55e-0461252IPR014811
DomainEF-hand_dom_typ1

DMD UTRN

6.55e-0461252IPR015153
DomainEF-hand_dom_typ2

DMD UTRN

6.55e-0461252IPR015154
DomainEF-hand_2

DMD UTRN

6.55e-0461252PF09068
DomainEF-hand_3

DMD UTRN

6.55e-0461252PF09069
DomainEGF_extracell

ADAM18 ADAM32 NTNG2 TNR

6.98e-04601254IPR013111
DomainEGF_2

ADAM18 ADAM32 NTNG2 TNR

6.98e-04601254PF07974
DomainPH

ASAP1 ARAP3 SBF1 FARP1 ARHGAP12 OSBPL8 FGD1

8.91e-042291257PF00169
DomainSpectrin_repeat

SYNE2 DMD UTRN

9.42e-04291253IPR002017
DomainCH

IQGAP2 SYNE2 DMD UTRN

9.44e-04651254SM00033
DomainEGF_LAM_2

NTNG1 NTNG2 USH2A

1.04e-03301253PS50027
DomainEGF_LAM_1

NTNG1 NTNG2 USH2A

1.04e-03301253PS01248
DomainDEAD_ATP_HELICASE

DDX3X DDX3Y DDX43

1.15e-03311253PS00039
DomainPIWI

PIWIL2 AGO4

1.21e-0381252PS50822
DomainFlavodoxin/NO_synth

TYW1 NOS1

1.21e-0381252IPR008254
DomainPiwi

PIWIL2 AGO4

1.21e-0381252SM00950
DomainDHC_N1

DNAH2 DNAH11

1.21e-0381252PF08385
DomainFlavdoxin-like

TYW1 NOS1

1.21e-0381252IPR001094
DomainPiwi

PIWIL2 AGO4

1.21e-0381252PF02171
DomainFLAVODOXIN_LIKE

TYW1 NOS1

1.21e-0381252PS50902
DomainPiwi

PIWIL2 AGO4

1.21e-0381252IPR003165
DomainFlavodoxin_1

TYW1 NOS1

1.21e-0381252PF00258
DomainDynein_heavy_dom-1

DNAH2 DNAH11

1.21e-0381252IPR013594
DomainCH

IQGAP2 SYNE2 DMD UTRN

1.25e-03701254PF00307
DomainSPEC

SYNE2 DMD UTRN

1.26e-03321253SM00150
DomainSpectrin/alpha-actinin

SYNE2 DMD UTRN

1.26e-03321253IPR018159
Domain-

IQGAP2 SYNE2 DMD UTRN

1.31e-037112541.10.418.10
DomainRNA-helicase_DEAD-box_CS

DDX3X DDX3Y DDX43

1.38e-03331253IPR000629
DomainDEAD/DEAH_box_helicase_dom

TDRD9 DDX3X DDX3Y DDX43

1.46e-03731254IPR011545
DomainCH

IQGAP2 SYNE2 DMD UTRN

1.46e-03731254PS50021
DomainDEAD

TDRD9 DDX3X DDX3Y DDX43

1.46e-03731254PF00270
DomainPAZ

PIWIL2 AGO4

1.55e-0391252PS50821
DomainPAZ

PIWIL2 AGO4

1.55e-0391252SM00949
DomainPAZ

PIWIL2 AGO4

1.55e-0391252PF02170
DomainPAZ_dom

PIWIL2 AGO4

1.55e-0391252IPR003100
DomainCH-domain

IQGAP2 SYNE2 DMD UTRN

1.61e-03751254IPR001715
DomainEGF_Lam

NTNG1 NTNG2 USH2A

1.64e-03351253SM00180
DomainLaminin_EGF

NTNG1 NTNG2 USH2A

1.64e-03351253PF00053
DomainEGF-like_CS

ADAM18 NTNG1 MUC12 ADAM32 NTNG2 HMCN2 TNR

1.89e-032611257IPR013032
DomainQ_MOTIF

DDX3X DDX3Y DDX43

1.93e-03371253PS51195
DomainRNA_helicase_DEAD_Q_motif

DDX3X DDX3Y DDX43

1.93e-03371253IPR014014
Domain-

TYW1 NOS1

1.93e-031012523.40.50.360
DomainFlavoprotein-like_dom

TYW1 NOS1

1.93e-03101252IPR029039
DomainEGF_2

ADAM18 NTNG1 MUC12 ADAM32 NTNG2 HMCN2 TNR

2.06e-032651257PS01186
DomainLaminin_EGF

NTNG1 NTNG2 USH2A

2.08e-03381253IPR002049
DomainVWFA

CACNA2D1 ITGA1 HMCN2 VWA3B

2.24e-03821254PS50234
DomainGDS_CDC24_CS

ARHGEF12 FARP1 FGD1

2.24e-03391253IPR001331
DomainPH_dom-like

ARHGEF12 ASAP1 ARAP3 SBF1 FARP1 ARHGAP12 OSBPL8 FGD1 NSMAF

2.29e-034261259IPR011993
DomainIL6Ra-bind

IL31RA IL6ST

2.35e-03111252PF09240
DomainTypeI_recpt_CBD

IL31RA IL6ST

2.35e-03111252IPR015321
DomainVWA

CACNA2D1 ITGA1 HMCN2 VWA3B

2.44e-03841254SM00327
DomainSAM

EPHB3 SAMD4B ARAP3 SCML1

2.89e-03881254SM00454
DomainNeurotransmitter_ion_chnl_CS

HTR3C CHRNE GABRA4

3.38e-03451253IPR018000
DomainNeur_chan_memb

HTR3C CHRNE GABRA4

3.60e-03461253PF02932
DomainSAM_DOMAIN

EPHB3 SAMD4B ARAP3 SCML1

3.81e-03951254PS50105
DomainNeurotrans-gated_channel_TM

HTR3C CHRNE GABRA4

3.83e-03471253IPR006029
Domain-

HTR3C CHRNE GABRA4

3.83e-034712532.70.170.10
DomainWW

ARHGAP12 DMD UTRN

3.83e-03471253PF00397
DomainNeur_chan_LBD

HTR3C CHRNE GABRA4

3.83e-03471253PF02931
DomainNEUROTR_ION_CHANNEL

HTR3C CHRNE GABRA4

3.83e-03471253PS00236
DomainNeur_channel

HTR3C CHRNE GABRA4

3.83e-03471253IPR006201
DomainNeur_chan_lig-bd

HTR3C CHRNE GABRA4

3.83e-03471253IPR006202
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH11

3.84e-03141252IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH11

3.84e-03141252IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH11

3.84e-03141252IPR013602
DomainDHC_N2

DNAH2 DNAH11

3.84e-03141252PF08393
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH11

3.84e-03141252IPR011704
DomainMT

DNAH2 DNAH11

3.84e-03141252PF12777
DomainAAA_8

DNAH2 DNAH11

3.84e-03141252PF12780
DomainAAA_5

DNAH2 DNAH11

3.84e-03141252PF07728
DomainWW

ARHGAP12 DMD UTRN

4.06e-03481253SM00456
DomainSAM

EPHB3 SAMD4B ARAP3 SCML1

4.10e-03971254IPR001660
DomainDHC_fam

DNAH2 DNAH11

4.41e-03151252IPR026983
DomainDynein_heavy

DNAH2 DNAH11

4.41e-03151252PF03028
DomainDynein_heavy_dom

DNAH2 DNAH11

4.41e-03151252IPR004273
DomainVWF_A

CACNA2D1 ITGA1 HMCN2 VWA3B

4.41e-03991254IPR002035
Pubmed

Neuronal nitric oxide synthase-rescue of dystrophin/utrophin double knockout mice does not require nNOS localization to the cell membrane.

DMD NOS1 UTRN

5.22e-083131322003386
Pubmed

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.

DMD NOS1 UTRN

5.22e-083131320483958
Pubmed

Neuronal nitric oxide synthase localizes to utrophin expressing intercalated discs and stabilizes their structural integrity.

DMD NOS1 UTRN

5.22e-083131326483274
Pubmed

Nestin expression in end-stage disease in dystrophin-deficient heart: implications for regeneration from endogenous cardiac stem cells.

NES DMD UTRN

5.22e-083131324068741
Pubmed

Proteins implicated in muscular dystrophy and cancer are functional constituents of the centrosome.

CAPN3 DMD UTRN

2.08e-074131335790299
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1A NES HDAC11 CACNA2D1 IQGAP2 ARHGEF12 ASAP1 PACS1 SBF1 SYNJ1 PTPRZ1 FARP1 OSBPL8 DDX3Y DMD TNR NOS1 UTRN EXOC4 DNAH11

4.31e-0714311312037142655
Pubmed

Dp71 gene disruption alters the composition of the dystrophin-associated protein complex and neuronal nitric oxide synthase expression in the hypothalamic supraoptic and paraventricular nuclei.

DMD NOS1 UTRN

5.19e-075131322493004
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

A2M CACNA2D1 DSG2 ITGA1 ADGRG6 HP PTPRZ1 IL6ST CNDP1

6.16e-07257131916335952
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NES CACNA2D1 IQGAP2 ARHGEF12 TEX10 JAKMIP2 TMEM132B DDX3X SPICE1 EPM2AIP1 SBF1 SYNJ1 FARP1 SYNE2 TNR NOS1

7.48e-079631311628671696
Pubmed

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration.

DSG2 ITGA1 PTGFRN MET ANO6

7.60e-0745131519581412
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH17 DNAH11

1.81e-067131331178125
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NES DSG2 SAMD4B DDX3X SPICE1 SBF1 SYNJ1 PIK3C2A SYNE2 OSBPL8 TRAPPC14 UTRN AHNAK2 EXOC4

4.93e-068611311436931259
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

EPHB3 NTNG1 NECTIN3 NTNG2 SLITRK6 SDK1

5.65e-06117131617145500
Pubmed

Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.

DMD NOS1 UTRN

8.43e-0611131310995443
Pubmed

gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.

DMD NOS1 UTRN

8.43e-0611131316857187
Pubmed

Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis.

NES RB1 FOXP1

1.12e-0512131324056077
Pubmed

Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.

DMD UTRN

1.41e-052131210525423
Pubmed

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

DMD UTRN

1.41e-052131228790199
Pubmed

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.

DMD UTRN

1.41e-052131225859846
Pubmed

alpha2-Macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species.

A2M HP

1.41e-052131219074141
Pubmed

Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear.

PTPRZ1 PTPRQ

1.41e-052131220715155
Pubmed

A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice.

DMD NOS1

1.41e-052131211581289
Pubmed

G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.

DMD UTRN

1.41e-05213127731967
Pubmed

Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.

MET PTPRZ1

1.41e-052131221454675
Pubmed

Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.

DMD UTRN

1.41e-052131216710609
Pubmed

Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.

DMD UTRN

1.41e-052131230672725
Pubmed

Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.

DMD UTRN

1.41e-05213127962191
Pubmed

mdx muscle pathology is independent of nNOS perturbation.

DMD NOS1

1.41e-05213129536086
Pubmed

Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?

DMD UTRN

1.41e-05213128021701
Pubmed

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.

DMD UTRN

1.41e-052131226974331
Pubmed

Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection.

DMD NOS1

1.41e-052131211717466
Pubmed

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.

DMD UTRN

1.41e-052131228453658
Pubmed

A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.

DMD UTRN

1.41e-052131211801396
Pubmed

Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.

DMD UTRN

1.41e-05213127987307
Pubmed

Comparative analysis of the human dystrophin and utrophin gene structures.

DMD UTRN

1.41e-052131211861579
Pubmed

Distinct mechanical properties in homologous spectrin-like repeats of utrophin.

DMD UTRN

1.41e-052131230914715
Pubmed

Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.

DMD UTRN

1.41e-052131222284942
Pubmed

Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.

DMD UTRN

1.41e-052131217889902
Pubmed

Diversification of behavior and postsynaptic properties by netrin-G presynaptic adhesion family proteins.

NTNG1 NTNG2

1.41e-052131226746425
Pubmed

Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.

DMD UTRN

1.41e-052131235557546
Pubmed

The susceptibility of muscle cells to oxidative stress is independent of nitric oxide synthase expression.

DMD NOS1

1.41e-052131211268022
Pubmed

Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.

DMD UTRN

1.41e-052131237626761
Pubmed

Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.

DMD UTRN

1.41e-052131215565469
Pubmed

Molecular clues about the dystrophin-neuronal nitric oxide synthase interaction: a theoretical approach.

DMD NOS1

1.41e-052131224063785
Pubmed

Laminets: laminin- and netrin-related genes expressed in distinct neuronal subsets.

NTNG1 NTNG2

1.41e-052131211906208
Pubmed

Human netrin-G1 isoforms show evidence of differential expression.

NTNG1 NTNG2

1.41e-052131215901489
Pubmed

The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.

DMD UTRN

1.41e-052131226516677
Pubmed

Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.

DMD UTRN

1.41e-052131222209498
Pubmed

A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.

DMD UTRN

1.41e-052131237108685
Pubmed

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

DMD UTRN

1.41e-052131210694796
Pubmed

RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas.

MET PTPRZ1

1.41e-052131225135958
Pubmed

Normal sulfation levels regulate spinal cord neural precursor cell proliferation and differentiation.

NES PTPRZ1

1.41e-052131222681904
Pubmed

Muscular dystrophy in mdx mice despite lack of neuronal nitric oxide synthase.

DMD NOS1

1.41e-05213129681470
Pubmed

Nitric oxide generated by muscle corrects defects in hippocampal neurogenesis and neural differentiation caused by muscular dystrophy.

DMD NOS1

1.41e-052131219237426
Pubmed

Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

DMD UTRN

1.41e-052131224337461
Pubmed

Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.

DMD UTRN

1.41e-052131211297940
Pubmed

Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.

DMD UTRN

1.41e-052131222388933
Pubmed

Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.

DMD UTRN

1.41e-052131225642938
Pubmed

Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.

DMD UTRN

1.41e-052131215703201
Pubmed

Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.

DMD UTRN

1.41e-052131225941878
Pubmed

Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS.

DMD NOS1

1.41e-052131222952904
Pubmed

Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.

DMD UTRN

1.41e-05213129297964
Pubmed

SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.

DMD UTRN

1.41e-052131225652448
Pubmed

Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.

DMD UTRN

1.41e-052131228785010
Pubmed

Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.

DMD UTRN

1.41e-052131216307000
Pubmed

Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy.

DMD NOS1

1.41e-05213127545544
Pubmed

Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.

DMD UTRN

1.41e-052131221949353
Pubmed

Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.

DMD UTRN

1.41e-052131223097179
Pubmed

The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.

DMD UTRN

1.41e-052131215501597
Pubmed

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.

DMD UTRN

1.41e-052131211257121
Pubmed

Netrin-G2 dysfunction causes a Rett-like phenotype with areflexia.

NTNG1 NTNG2

1.41e-052131231692205
Pubmed

Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.

DMD UTRN

1.41e-052131218973234
Pubmed

Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.

DMD UTRN

1.41e-052131227881412
Pubmed

Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.

DMD UTRN

1.41e-052131220625423
Pubmed

Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.

DMD UTRN

1.41e-052131229065908
Pubmed

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.

DMD UTRN

1.41e-052131231039133
Pubmed

A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia.

NTNG1 NTNG2

1.41e-052131215705354
Pubmed

Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain.

DMD UTRN

1.41e-052131211796130
Pubmed

Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.

DMD UTRN

1.41e-05213128159184
Pubmed

Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.

DMD UTRN

1.41e-052131210679963
Pubmed

TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.

DMD UTRN

1.41e-052131221565990
Pubmed

Generation and characterization of transgenic mice with the full-length human DMD gene.

DMD UTRN

1.41e-052131218083704
Pubmed

Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.

DMD UTRN

1.41e-05213128186702
Pubmed

Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.

DMD UTRN

1.41e-052131225940966
Pubmed

Cardiac dysfunction and pathology in the dystrophin and utrophin-deficient mouse during development of dilated cardiomyopathy.

DMD UTRN

1.41e-052131222266080
Pubmed

Postnatal overexpression of the CT GalNAc transferase inhibits muscular dystrophy in mdx mice without altering muscle growth or neuromuscular development: evidence for a utrophin-independent mechanism.

DMD UTRN

1.41e-052131217300937
Pubmed

Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice.

DMD UTRN

1.41e-052131221768542
Pubmed

Social stress is lethal in the mdx model of Duchenne muscular dystrophy.

DMD UTRN

1.41e-052131232192914
Pubmed

Lack of hepatic c-Met and gp130 expression is associated with an impaired antibacterial response and higher lethality after bile duct ligation.

MET IL6ST

1.41e-052131222986785
Pubmed

Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity.

DMD UTRN

1.41e-052131233359740
Pubmed

Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle.

DMD UTRN

1.41e-052131224879867
Pubmed

High-sensitive clinical diagnostic method for PTPRZ1-MET and the characteristic protein structure contributing to ligand-independent MET activation.

MET PTPRZ1

1.41e-052131233645009
Pubmed

Increased vulnerability to kainate-induced seizures in utrophin-knockout mice.

DMD UTRN

1.41e-052131212028357
Pubmed

Excitation-contraction coupling alterations in mdx and utrophin/dystrophin double knockout mice: a comparative study.

DMD UTRN

1.41e-052131220130206
Pubmed

Analysis of gene expression differences between utrophin/dystrophin-deficient vs mdx skeletal muscles reveals a specific upregulation of slow muscle genes in limb muscles.

DMD UTRN

1.41e-052131216525850
Pubmed

Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy.

DMD NOS1

1.41e-05213128799168
Pubmed

Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.

DMD UTRN

1.41e-052131220434517
Pubmed

Sarcolemmal targeting of nNOSμ improves contractile function of mdx muscle.

DMD NOS1

1.41e-052131226604149
Pubmed

Dsg2-mediated c-Met activation in anaplastic thyroid cancer motility and invasion.

DSG2 MET

1.41e-052131233022637
Pubmed

Plasma lipidomic analysis shows a disease progression signature in mdx mice.

DMD UTRN

1.41e-052131234155298
InteractionFBXO2 interactions

CACNA2D1 MANBA ITGA1 NECTIN3 NCLN PTGFRN ADGRG6 MET ANO6 SYNE2 OSBPL8 TTC17 IL6ST

2.64e-0641113013int:FBXO2
InteractionCDC42 interactions

A2M FKBP10 ATP6V1A IQGAP2 DSG2 ATL3 ARHGEF12 MUC12 ITGA1 NECTIN3 NCLN TEX10 TRRAP SBF1 PIK3C2A ANO6 FARP1 SYNE2 OSBPL8 FGD1 TYW1 UTRN IL6ST

1.18e-05132313023int:CDC42
InteractionRHOC interactions

DSG2 ARHGEF12 ITGA1 NECTIN3 NCLN ADGRG6 MET SBF1 ANO6 FARP1 SYNE2 OSBPL8 UTRN IL6ST

2.52e-0558413014int:RHOC
InteractionRAC2 interactions

DSG2 ITGA1 NECTIN3 NCLN TRRAP ADGRG6 SBF1 PIK3C2A ANO6 FARP1 SYNE2 OSBPL8 TYW1 UTRN IL6ST

3.02e-0567413015int:RAC2
Cytoband6p21.31

IP6K3 ARMC12 LEMD2

2.24e-044113136p21.31
Cytoband5q11.2

IL31RA ITGA1 IL6ST

4.53e-045213135q11.2
GeneFamilyFibronectin type III domain containing

EPHB3 IL31RA PTPRO PTPRZ1 PTPRQ TNR USH2A SDK1 IL6ST

2.77e-071601019555
GeneFamilyDyneins, axonemal

DNAH2 DNAH17 DNAH11

1.09e-04171013536
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ASAP1 ARAP3 SBF1 FARP1 ARHGAP12 OSBPL8 FGD1

1.57e-042061017682
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRO PTPRZ1 PTPRQ

2.09e-04211013813
GeneFamilyNetrins

NTNG1 NTNG2

4.57e-0461012661
GeneFamilyImmunoglobulin like domain containing

NECTIN3 IL1RL2 PTGFRN HMCN2 LY9 SDK1

7.49e-041931016594
GeneFamilyArgonaute/PIWI family

PIWIL2 AGO4

8.46e-0481012408
GeneFamilySterile alpha motif domain containing

EPHB3 SAMD4B ARAP3 SCML1

1.49e-03881014760
GeneFamilyDEAD-box helicases

DDX3X DDX3Y DDX43

1.66e-03421013499
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL31RA IL1RL2 IL6ST

1.66e-03421013602
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DMD UTRN

4.46e-0318101291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF12 FARP1 FGD1

6.00e-03661013722
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

NES IQGAP2 ARHGEF12 NTNG1 ITGA1 PTPRO PCNX4 PTPRQ UTRN

1.26e-062121319M39221
CoexpressionLAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES

CACNA2D1 ARHGEF12 ITGA1 ASAP1 PIK3C2A UTRN IL6ST

5.95e-061371317M39241
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ANK1 LOXHD1 PTPRQ DMD ATP1A4 USH2A SDK1 DNAH11

3.78e-0918413092cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ANK1 LOXHD1 PTPRQ DMD ATP1A4 USH2A SDK1 DNAH11

3.78e-091841309ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ANK1 LOXHD1 PTPRQ DMD ATP1A4 USH2A SDK1 DNAH11

3.78e-0918413092b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRMT9B DNAH2 PTPRZ1 VWA3B CPLANE1 SDK1 AHNAK2 DNAH11

1.03e-071931308ea345d34440b25f65358a53dc72831998d1c3620
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

ITGA1 ASAP1 ADGRG6 ARAP3 PIK3C2A SYNE2 FOXP1 IL6ST

1.03e-0719313082531266bc57339d4e2b22a88817008e32b8c1598
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH2 CDKL1 SYNE2 VWA3B DMD CPLANE1 CCDC180 DNAH11

1.21e-07197130874a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 RB1 NECTIN3 ASAP1 SCML1 FOXP1 DMD UTRN

1.30e-071991308358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH2 TSPAN19 JAKMIP2 HP PTPRZ1 CCDC180 DNAH11

5.45e-071641307e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH2 TSPAN19 CFAP92 WDR97 ABCA5 VWA3B DNAH11

9.45e-0717813073b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M NES ITGA1 ADGRG6 ANO6 DMD UTRN

1.27e-061861307888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

ITGA1 ASAP1 ADGRG6 ARAP3 PIK3C2A FOXP1 IL6ST

1.41e-061891307c81787a8c662db5d7814c583dd64562857629e81
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

A2M ITGA1 ASAP1 ADGRG6 ARAP3 PIK3C2A SYNE2

1.51e-061911307c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MANBA ASAP1 FOXP1 SPIDR UTRN IL6ST EXOC4

1.62e-061931307779276e775cb2492e8dd36436295a536084a6415
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH2 TSPAN19 DCDC2B CDKL1 VWA3B CCDC180 DNAH11

1.74e-0619513073486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

A2M ITGA1 ASAP1 ARAP3 PIK3C2A SYNE2 UTRN

1.86e-061971307f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ARHGEF12 ARAP3 AGO4 PIK3C2A SYNE2 FOXP1 UTRN

2.06e-062001307dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

A2M NES ITGA1 ADGRG6 ANO6 SYNE2 DMD

2.06e-0620013070c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M NES ITGA1 ADGRG6 ANO6 SYNE2 DMD

2.06e-062001307522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FKBP10 ITGA1 ADGRG6 MET DMD SLITRK6 ATP1A4

2.06e-06200130709537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

A2M NES ITGA1 ADGRG6 ANO6 SYNE2 DMD

2.06e-06200130794f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAKMIP2 TMEM132B TMEM269 HMCN2 PTPRZ1 SLITRK6

6.13e-06154130630cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAKMIP2 TMEM132B TMEM269 HMCN2 PTPRZ1 SLITRK6

6.13e-061541306ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAKMIP2 TMEM132B TMEM269 HMCN2 PTPRZ1 SLITRK6

6.13e-06154130642bd8f88fd075a2d4edde394785decad88a2660a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAKMIP2 TMEM132B TMEM269 HMCN2 PTPRZ1 SLITRK6

6.13e-0615413066425d9861148586466febd6eceae1b1f9b9a14c1
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

FKBP10 SYNE2 FGD1 SLITRK6 SDK1 DNAH11

6.60e-06156130610d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FKBP10 NES HMX1 ADGRG6 MET TNR

6.85e-061571306b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES ITGA1 TMEM132B ADGRG6 PTPRZ1 SLITRK6

1.01e-051681306af82e07d1eec51fc6530155f37addbce6221885d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.01e-051681306fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.01e-051681306315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M NES ITGA1 ASAP1 ARAP3 IL6ST

1.01e-05168130637249f38f8f04ec5743097259de67b106ca2b02f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARAP3 PTPRQ DDX43 USH2A

1.08e-05471304b83e9a0f8db3f1581c5621f9d835ae2423ba0978
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.15e-0517213066c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.15e-051721306381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.23e-051741306dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A DSG2 LOXHD1 ABCA5 PCNX4 FOXP1

1.27e-05175130677c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A DSG2 LOXHD1 ABCA5 PCNX4 FOXP1

1.27e-05175130698947a226b5a2ac7091ff9d34243ea7736add973
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A DSG2 LOXHD1 ABCA5 PCNX4 FOXP1

1.31e-05176130625ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 CAPN3 CHRNE ARAP3 PTPRO CD40LG

1.31e-0517613063d372c1d527fcc118d1e5809f2524fc387682472
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A DSG2 LOXHD1 ABCA5 PCNX4 FOXP1

1.31e-051761306c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellfacs-Skin-Telogen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 CAPN3 CHRNE ARAP3 PTPRO CD40LG

1.31e-0517613067b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 CAPN3 CHRNE ARAP3 PTPRO CD40LG

1.31e-0517613069c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.36e-0517713064d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 DCDC2B TMC3 VWA3B SLITRK6 DNAH11

1.36e-051771306c38138fb5ad9766c2d240811210c854338cd612e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.40e-051781306edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH2 TSPAN19 WDR97 VWA3B SDK1 DNAH11

1.45e-0517913065e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FKBP10 IP6K3 FARP1 DMD SLITRK6 SDK1

1.45e-051791306a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRMT9B ATP6V1A IQGAP2 SCML1 FOXP1 DNAH11

1.49e-051801306cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES ITGA1 TMEM132B ADGRG6 PTPRZ1 SLITRK6

1.54e-051811306a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

A2M TRMT9B ITGA1 HMCN2 DMD SDK1

1.64e-051831306818fd886e0188091310825f9145fa53328f2c979
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 CAPN3 NTNG1 TMEM269 PTPRZ1 SLITRK6

1.64e-051831306876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 CAPN3 NTNG1 TMEM269 PTPRZ1 SLITRK6

1.64e-051831306b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FKBP10 TMEM132B ADGRG6 MET DMD SLITRK6

1.64e-0518313067eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES IQGAP2 NTNG1 JAKMIP2 PTPRO PTPRQ

1.64e-051831306612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M TRMT9B ITGA1 HMCN2 DMD SDK1

1.64e-051831306cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

DSG2 ADAM32 ADGRG6 SCML1 DMD SDK1

1.69e-051841306ee295f6fa898da53883e1358b17f2c2dd177e9a7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

CACNA2D1 ANO6 FARP1 PTPRQ DMD CPLANE1

1.74e-05185130632b4e68e551d435a732f253f6ad83408c759a642
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

1.74e-0518513065e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

A2M TRMT9B ITGA1 HMCN2 DMD SDK1

1.91e-05188130634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M IP6K3 FARP1 DMD SLITRK6 SDK1

1.91e-051881306997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTNG1 ADGRG6 PTPRO NOS1 SDK1 CA1

1.91e-0518813063139540a656c0436b2123ea50741ff8d00112165
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M NES ITGA1 ARAP3 CFAP92 IL6ST

1.97e-051891306e60a3d6aa84788c29f23439f1c747431ea581bc3
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ARHGEF12 OAZ2 ITGA1 ADGRG6 SYNE2 DNAH11

1.97e-0518913069c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M TRMT9B ITGA1 HMCN2 DMD SDK1

1.97e-0518913066b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

ITGA1 ASAP1 ADGRG6 PIK3C2A FOXP1 IL6ST

1.97e-05189130675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellLAM-Epithelial-AirwayEpi|LAM / Condition, Lineage and Cell class

DNAH2 TSPAN19 DCDC2B VWA3B SLITRK6 DNAH11

2.15e-0519213067404fc65be3b7bd09447725b43fa31819004dfee
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

A2M ITGA1 ARAP3 PIK3C2A SYNE2 UTRN

2.15e-0519213068a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 ITGA1 ADGRG6 FARP1 NOS1 UTRN

2.15e-051921306dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 ITGA1 ADGRG6 FARP1 NOS1 UTRN

2.21e-051931306c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

ITGA1 ASAP1 ADGRG6 ARAP3 PIK3C2A IL6ST

2.21e-05193130601c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

A2M ITGA1 ARAP3 PIK3C2A SYNE2 UTRN

2.21e-051931306e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 IQGAP2 ABCA5 PTPRZ1 DDX3Y DMD

2.21e-0519313061aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB3 DSG2 RB1 NTNG1 MET HP

2.28e-0519413060ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

ASAP1 ADGRG6 ARAP3 PIK3C2A FOXP1 IL6ST

2.28e-051941306b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.28e-0519413061ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

TSPAN19 ARHGEF12 SYNE2 VWA3B SDK1 DNAH11

2.34e-051951306fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

A2M ITGA1 ASAP1 ARAP3 PIK3C2A SYNE2

2.34e-051951306fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

TSPAN19 ARHGEF12 SYNE2 VWA3B SDK1 DNAH11

2.34e-051951306eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.34e-051951306e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M NES ITGA1 ARAP3 ANO6 IL6ST

2.41e-051961306d323f7dc41380446e5967c69832bea88351a9331
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

TSPAN19 ARHGEF12 MET SYNE2 SDK1 DNAH11

2.41e-051961306af4cdc61830685a888a1209826c23bcf54a43084
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.41e-051961306686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.41e-05196130667aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.41e-051961306ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.41e-0519613061cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

TSPAN19 ARHGEF12 MET SYNE2 SDK1 DNAH11

2.41e-0519613066d02d494196e3f857d53eea46d9419690d43beca
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.41e-051961306d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.41e-05196130669f5081e06d84ec1d9695762df801a9d0df1984b
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

A2M ITGA1 ASAP1 ARAP3 PIK3C2A SYNE2

2.48e-051971306ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NES IP6K3 TMEM132B PTPRZ1 DMD SLITRK6

2.48e-051971306b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ITGA1 ASAP1 DMD UTRN IL6ST

2.48e-0519713069b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

EPHB3 FARP1 SYNE2 PTPRQ IFT80 UTRN

2.55e-05198130685f424cd9bb3117c9e322031024aabb87696ce47
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES ITGA1 TMEM132B ADGRG6 PTPRZ1 SLITRK6

2.55e-05198130652ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ASAP1 ADGRG6 ARAP3 UTRN IL6ST

2.55e-051981306259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

A2M FKBP10 CACNA2D1 NTNG1 ITGA1 SDK1

2.63e-0519913064bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M ADGRG6 PIK3C2A FOXP1 NOS1 IL6ST

2.63e-05199130668412bc39639edc4045437d62548f7101b9f1989
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB3 FARP1 SYNE2 PTPRQ IFT80 UTRN

2.63e-051991306a270630626df614f8605abddb7dee7c4d74f6149
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FKBP10 CACNA2D1 TMEM132B ADGRG6 DMD SLITRK6

2.63e-0519913066b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.70e-05200130652aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TDRD9 DNAH2 TSPAN19 PTPRZ1 VWA3B CCDC180

2.70e-05200130696701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH2 TSPAN19 DCDC2B VWA3B CCDC180 DNAH11

2.70e-05200130655c148238d5c80c1faa3428a917ae8075be2c145
Diseaseacute kidney failure (biomarker_via_orthology)

NES RB1 MET HP NOS1

6.44e-06611265DOID:3021 (biomarker_via_orthology)
Diseasehepatocellular carcinoma (biomarker_via_orthology)

A2M RB1 CAPN3 MET FOXP1 IL6ST

7.21e-061081266DOID:684 (biomarker_via_orthology)
Diseasechildhood medulloblastoma (implicated_via_orthology)

DDX3X DDX3Y

1.81e-0521262DOID:3869 (implicated_via_orthology)
Diseasenetrin-G1 measurement

NTNG1 NTNG2

5.41e-0531262EFO_0801825
Diseaselifestyle measurement

ERCC8 PACS1 ARAP3 FARP1 FOXP1 SLITRK6 EXOC4

7.03e-052351267EFO_0010724
DiseaseSertoli cell-only syndrome (implicated_via_orthology)

DDX3X DDX3Y

1.08e-0441262DOID:0050457 (implicated_via_orthology)
Diseasehepatocellular adenoma (biomarker_via_orthology)

A2M HP

1.79e-0451262DOID:0050868 (biomarker_via_orthology)
DiseaseDuchenne muscular dystrophy (is_marker_for)

DMD NOS1

1.79e-0451262DOID:11723 (is_marker_for)
Diseasephosphate measurement

IP6K3 LEMD2

3.75e-0471262EFO_0010968
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CAPN3 DMD UTRN

4.90e-04361263DOID:11723 (implicated_via_orthology)
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma

IQGAP2 PFKFB3 DMD

6.21e-04391263EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Diseasemultisite chronic pain

IP6K3 LEMD2 UTRN SDK1

7.48e-04951264EFO_0010100
Diseasecardiovascular system disease (is_marker_for)

HP CD40LG

7.96e-04101262DOID:1287 (is_marker_for)
Diseaseresponse to bisphosphonate, osteonecrosis

NTNG1 NTNG2

7.96e-04101262EFO_0004259, EFO_0009958
Diseaselevel of Sphingomyelin (d34:0) in blood serum

CHRNE SYNE2

9.70e-04111262OBA_2045176
Diseaselifestyle measurement, depressive symptom measurement

HDAC11 ASAP1 NSMAF EXOC4

1.09e-031051264EFO_0007006, EFO_0010724
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

LEMD2 SYNE2

1.16e-03121262DOID:11726 (implicated_via_orthology)
Diseaseserum alanine aminotransferase measurement

MANBA SAMD4B PKD1L1 DNAH2 NTNG1 ITGA1 MLYCD MET NTNG2 IFT80 CARS2

1.28e-0386912611EFO_0004735
DiseaseCiliopathies

IFT80 CPLANE1 USH2A DNAH11

1.29e-031101264C4277690
DiseasePneumoconiosis

PTPRZ1 CA1

1.59e-03141262C0032273
DiseaseBagassosis

PTPRZ1 CA1

1.59e-03141262C0004681
DiseaseCongenital total cataract

LEMD2 AGK

2.09e-03161262C0266539
DiseaseAstrocytosis

ITGA1 TNR

2.36e-03171262C3887640
DiseaseGliosis

ITGA1 TNR

2.36e-03171262C0017639
DiseaseAllergic Reaction

HP CD40LG IL6ST

2.50e-03631263C1527304
DiseaseHypersensitivity

HP CD40LG IL6ST

2.62e-03641263C0020517
Diseaseesophageal adenocarcinoma

HTR3C FOXP1

2.65e-03181262EFO_0000478
Diseasecaudal middle frontal gyrus volume measurement

PCNX4 NSMAF

2.65e-03181262EFO_0010290
Diseaseneuroticism measurement, wellbeing measurement, depressive symptom measurement

FARP1 SDK1

2.95e-03191262EFO_0007006, EFO_0007660, EFO_0007869
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 SLITRK6

2.95e-03191262DOID:10003 (implicated_via_orthology)
Diseaseradiation-induced disorder

NTNG1 MUC12 NTNG2

2.98e-03671263EFO_0009565
DiseaseIntellectual Disability

TRRAP DDX3X PACS1 SNX14 NTNG2 ZBTB40 CNDP1

3.15e-034471267C3714756
Diseaseatherosclerosis (biomarker_via_orthology)

HP CD40LG

3.27e-03201262DOID:1936 (biomarker_via_orthology)
Diseasealpha-tocopherol measurement

CACNA2D1 USH2A

3.27e-03201262EFO_0007898
Diseaseanorexia nervosa

NTNG1 NTNG2 FOXP1

3.38e-03701263MONDO_0005351
DiseaseManic Disorder

NTNG1 PACS1 NTNG2

3.52e-03711263C0024713
Diseasemuscular dystrophy (implicated_via_orthology)

DMD UTRN

3.60e-03211262DOID:9884 (implicated_via_orthology)
Diseasepentachlorophenol measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022071
Diseaseparathion measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022070
Diseasepotassium chromate measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022072
Diseasemercuric chloride measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022068
Diseaseheptachlor epoxide measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022067
Diseasemethoxychlor measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022069
Disease4,6-dinitro-o-cresol measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022053
Disease2,4,5-trichlorophenol measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022052
Diseaseazinphos methyl measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022055
Diseasealdrin measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022054
Diseasedicofol measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022060
Diseasedisulfoton measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022062
Diseasedieldrin measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022061
Diseaseendrin measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022064
Diseaseendosulfan measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022063
Diseaseheptachlor measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022066
Diseaseethion measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022065
Diseasechlorpyrifos measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022057
Diseasecadmium chloride measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022056
Diseasediazinon measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022059
Diseasedibutyl phthalate measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0022058
Diseaseenvironmental exposure measurement

NTNG1 NTNG2 USH2A

3.80e-03731263EFO_0008360
Diseaseblood pressure

TNR EXOC4

3.95e-03221262EFO_0004325
DiseaseDDT metabolite measurement

NTNG1 NTNG2 USH2A

3.95e-03741263EFO_0007886
DiseaseParkinson's disease (is_implicated_in)

A2M SYNJ1 NOS1

4.26e-03761263DOID:14330 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
ILQLRETESSAVKWT

nan

126

A4D1N5
QLKTNVSLWKELEST

ABCA5

186

Q8WWZ7
EVWKDVQLSTIELSI

AGK

301

Q53H12
VQSLKLDTSVWSNEI

ARAP3

541

Q8WWN8
AQIDLEVSLITTWKD

ARAP3

1096

Q8WWN8
EVSLITTWKDVQLSQ

ARAP3

1101

Q8WWN8
VISEASSKTTSVLQW

CD40LG

126

P29965
EVKVQSKVAEWLNST

ADGRG6

426

Q86SQ4
KLTVILSSLELWSNE

ADAM18

226

Q9Y3Q7
EKVLVSVSEHTWTEQ

ANK1

1751

P16157
NELKWSFAVATITEI

HDAC11

81

Q96DB2
GTEKVITEISQTWAT

DNAH11

1456

Q96DT5
ITDTSRKVIQTQGEW

HTR3C

201

Q8WXA8
QFKVTIVLSSLELWS

ADAM32

226

Q8TC27
WEQTFNITVTKELLK

CFAP92

166

Q9ULG3
ITKWIIQADTLLDES

DMD

1691

P11532
QTFKVSVQWVSVVSL

AGO4

116

Q9HCK5
TVTTEELLSFVQTWK

CCDC180

1166

Q9P1Z9
QLFIATVTETEKQWT

CBWD5

371

Q5RIA9
SIKVLELISTIWDTE

ARMC12

151

Q5T9G4
ISLNEKEETLTTSVW

CHRNE

61

Q04844
EDLTSATNIVKWITK

A2M

1226

P01023
ELVAQTVSEKTVWQD

ARHGEF12

1111

Q9NZN5
ISTEINSALVLKVSW

RB1

181

P06400
VQSKAVSDWLIASVE

NCLN

191

Q969V3
LNWFTKVLSVDESII

ANO6

161

Q4KMQ2
NWISVDSVTSEIKLA

DSG2

436

Q14126
TSENITQKVVWVEES

DDX3X

411

O00571
TEVKVSSWDAVLSSQ

OAZ2

86

O95190
ASTVLSLAEKWIQQI

JAKMIP2

656

Q96AA8
KVTSIQDWVQKTIAE

HP

391

P00738
VAEDQLVVKWQSSAL

IL31RA

336

Q8NI17
IWLKGEDQSELVTTV

LEMD2

336

Q8NC56
VTEVLKWVESAIQAS

HMCN2

201

Q8NDA2
STEWDTFIEQILKNT

HPS4

136

Q9NQG7
WLVEKVEVTNTSTGV

LOXHD1

2026

Q8IVV2
INETLKLLLSSSEWV

MLYCD

371

O95822
QLFIATVTETEKQWT

CBWD2

371

Q8IUF1
QLFIATVTETEKQWT

CBWD1

371

Q9BRT8
TVTETEKQWTTRFQE

CBWD1

376

Q9BRT8
LQFAVTVLLTSWTEK

PCNX4

541

Q63HM2
VKEAWTTTEQLQFTI

PIK3C2A

676

O00443
DTEVLTIKNVSAITW

SLC10A3

111

P09131
VWTSQLKSTIQTAEA

PFKFB3

296

Q16875
LAASLQLTETQVKIW

HMX1

236

Q9NP08
TELQQLWKEVTSAHT

FOXP1

226

Q9H334
IEGKVVSSLQQEIWE

NES

511

P48681
VISNVNETSLILEWS

EPHB3

346

P54753
VILSQVSFWINKESV

GABRA4

271

P48169
WIVFKDTVSISESQL

PTPRZ1

246

P23471
SSDISQVNVSLILWK

ITGA1

1076

P56199
KVSTESAAVAIWQTL

IP6K3

96

Q96PC2
VLKWSVTQALDVTEQ

PLCXD1

81

Q9NUJ7
DKTLKVWDTNTLQTA

ERCC8

121

Q13216
KSTWIKNQDDSLTET

PACS1

441

Q6VY07
TVINDWFKVLSSTIN

ARHGAP12

561

Q8IWW6
WDITTQVVSLVQLLS

SBF1

1426

O95248
TSSLWKDQALVEINI

NOS1

626

P29475
AVNKTQTSVTLLWVE

PTPRO

731

Q16827
QLAEVESTQVRITWK

PTPRQ

446

Q9UMZ3
TETVSEENKSLIWTL

OSBPL8

396

Q9BZF1
EQTTSQVSWEQDLKL

FCHSD1

271

Q86WN1
SKIIQSRIHQDETWI

IL1RL2

66

Q9HB29
IVQSEEKLVISASWA

EXOC4

626

Q96A65
LLDVWNKEDTVQVST

FKBP10

146

Q96AY3
QIVKWNLLTSETTQI

IFT80

36

Q9P2H3
INSEELSSILKLTWT

IL6ST

231

P40189
DSITTWQFVVVSLKA

C3P1

36

Q6ZMU1
LKDVIVLTTSSNDAW

CPLANE1

61

Q9H799
VVVVNTSIEDWKTTK

DNAH17

1286

Q9UFH2
EVTSWQQKLSTADSV

DNAH17

1471

Q9UFH2
IDVNSWIENFTKTSI

CACNA2D1

816

P54289
EHLVKSITWQTLQAV

CDKL1

101

Q00532
LKDLEVITSWFQSTV

FARP1

556

Q9Y4F1
LKLSQAASQDWETVL

DCDC2B

146

A2VCK2
QIINTISEWIVLIKT

EPM2AIP1

296

Q7L775
ESVTWIICKESISVS

CA1

206

P00915
QLFIATVTETEKQWT

CBWD3

371

Q5JTY5
QLFIATVTETEKQWT

CBWD6

371

Q4V339
SIEVLVWSQVTKTEI

ADGRF2

466

Q8IZF7
AWISVLTNSKEEALT

ASAP1

406

Q9ULH1
TTGIQIWSEVFTVEK

ATL3

116

Q6DD88
ELFVNISKNITVETW

MANBA

276

O00462
DTEKVVWLFNTSIIS

LY9

276

Q9HBG7
TEESKTLAWNNITKL

NSMAF

606

Q92636
VGSTSENITQKVVWV

DDX3Y

406

O15523
DTTSVDIIVTENIWK

CDH17

226

Q12864
LQSDKLQTWTVSVNE

CAPN3

421

P20807
VKIIASDNLWESISA

GALC

221

P54803
VITASQIQWTADVTK

DNAH2

1651

Q9P225
TQILLTWTSVPEQDQ

SDK1

1291

Q7Z5N4
NIWKTTSEAALSVVN

PKD1L1

96

Q8TDX9
VKQNIIVTTEEEKWS

DDX43

461

Q9NXZ2
QVNITLSWSKTIELT

NTNG1

131

Q9Y2I2
LSWSKTIELTDNIVI

NTNG1

136

Q9Y2I2
ANITLSWNKTVELTD

NTNG2

121

Q96CW9
ISLDQDSVVKLENWT

PTGFRN

606

Q9P2B2
ELNIEWKQAISSTVL

MET

906

P08581
TWTKIDNLEDTIVLN

USH2A

3506

O75445
TLQVTGSESIEITWK

USH2A

4451

O75445
DLQQTNSEKILLSWV

UTRN

146

P46939
LSEWLSATETELVQK

UTRN

1556

P46939
LKWIQEAETTVNVLV

UTRN

2456

P46939
STWSVEAVVLFLKQT

SCML1

256

Q9UN30
TTSTWELLDQRTKDQ

CARS2

546

Q9HA77
LWEKNEVSVVVSLVT

TMC3

356

Q7Z5M5
WIQKLSKNTVTDDIL

SLITRK6

531

Q9H5Y7
LKWSLVSLDENVVIS

TMEM132B

271

Q14DG7
NTVVLWENTKALVTE

SYNE2

1511

Q8WXH0
VSASTTNQKLWAVEL

SYNJ1

601

O43426
CVWIEKESINSVIIS

TDRD9

1171

Q8NDG6
LSLSLTETQVKIWFQ

NKX1-1

331

Q15270
ITSQELNWVKEVTRD

PIWIL2

581

Q8TC59
SVSKVLWLDEIQQAV

IQGAP2

511

Q13576
TFIDNTDSIVKIQSW

IQGAP2

716

Q13576
VNTWTERSTQFKVII

FGD1

481

P98174
NVDLTSSITWVKQAE

SRR

316

Q9GZT4
TSVKQEWDNTVTDLT

SPICE1

26

Q8N0Z3
VNVDQLWEDSVLTVK

AHNAK2

5371

Q8IVF2
TIVVVQWADLIISKT

ATP1A4

931

Q13733
QTLKEWVAIESDSVQ

CNDP1

51

Q96KN2
INEVSWKDVTSALSL

TMEM269

26

A0A1B0GVZ9
DNWLLAKSTKNETIT

THOC2

961

Q8NI27
IWDVTSQATLLTITK

WDR88

256

Q6ZMY6
VVTWETVQKENFLSK

TRPM5

1051

Q9NZQ8
NDVKTLLREWITTIS

REV1

1166

Q9UBZ9
WQQESKEKVVSLLLS

SAMD4B

71

Q5PRF9
ELNKVQKEVTSVTSW

SNX14

931

Q9Y5W7
KVLNSSSQEEISIWD

TRAPPC14

241

Q8WVR3
IWLLVTDVTLQTKEE

SPIDR

671

Q14159
VLEWLSSKTVFQTEA

WDR97

581

A6NE52
LQFKTITETTVEVQW

TNR

421

Q92752
ITTLKSGSVQEQWLT

TEX10

891

Q9NXF1
ETTAQSDNKITWSII

ATP6V1A

556

P38606
VSIQLVDCKWLTVSE

RHPN2P1

456

A8MT19
VTWLQIASSVLKVSI

SLC7A13

156

Q8TCU3
IVSTWLAVSSKNIDI

TTC17

916

Q96AE7
LKNTEVWASSTVTVQ

TRMT9B

271

Q9P272
VNVTKTWEEQTETLR

ULBP1

81

Q9BZM6
SISLWICVQIVIKTQ

TYW1

31

Q9NV66
WINTKTDLAEQSLIS

VWA3B

21

Q502W6
VTEQSIATAISWVEK

VWA3B

196

Q502W6
EDITKWTILNALQKT

TSPAN19

136

P0C672
ISIIVKNDDSWLASQ

TRRAP

1646

Q9Y4A5
VLEKQTLSATAIWQL

ZBTB40

521

Q9NUA8
LDKLATVISVWNSDT

GEMIN4

266

P57678
TLWTGEVLEKQTVEQ

MUC12

36

Q9UKN1
EVNETITQISWEKIH

NECTIN3

81

Q9NQS3