Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF611 ZNF432 ZNF561 NR2F6 ZNF263 ZNF182 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 TSHZ2 ZNF709 RXRA GFI1 ZNF840P NR2F1 RXRB RXRG MAZ ZNF197 SP7 ZNF445	7.06e-16	1412	43	23	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF611 ZNF432 ZNF561 NR2F6 ZNF263 ZNF182 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF709 PRDM14 RXRA GFI1 ZNF840P NR2F1 RXRB RXRG MAZ ZNF197 SP7 ZNF445	1.44e-15	1459	43	23	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF611 ZNF432 ZNF561 NR2F6 ZNF263 ZNF182 ZNF225 ZNF519 PRDM5 ZNF99 ZNF709 RXRA GFI1 ZNF840P NR2F1 RXRB RXRG MAZ ZNF197 SP7 ZNF445	1.15e-14	1244	43	21	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF611 ZNF432 ZNF561 NR2F6 ZNF263 ZNF182 ZNF225 ZNF519 PRDM5 ZNF99 ZNF709 RXRA GFI1 ZNF840P NR2F1 RXRB RXRG MAZ ZNF197 SP7 ZNF445	1.76e-14	1271	43	21	GO:0000987
GeneOntologyMolecularFunction	retinoic acid-responsive element binding	RXRA NR2F1 RXRB RXRG	6.49e-10	7	43	4	GO:0044323
GeneOntologyMolecularFunction	nuclear receptor activity	NR2F6 RXRA NR2F1 RXRB RXRG	1.82e-07	60	43	5	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	NR2F6 RXRA NR2F1 RXRB RXRG	1.98e-07	61	43	5	GO:0098531
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	BNC1 ZNF225 ZNF519 ZNF99 ZNF709 ZNF840P RXRB ZNF197 SP7 ZNF445	2.55e-07	566	43	10	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF225 ZNF519 ZNF99 ZNF709 ZNF840P RXRB ZNF197 SP7 ZNF445	2.42e-06	560	43	9	GO:0001228
GeneOntologyMolecularFunction	molecular adaptor activity	ZNF432 COL19A1 KMT2E KAT6B ZNF99 ADAM10 CEBPZ ZNF709 ZNF653 GFI1 RXRB RXRG FIZ1	3.30e-06	1356	43	13	GO:0060090
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	ZNF432 COL19A1 KMT2E KAT6B ZNF99 CEBPZ ZNF709 ZNF653 GFI1 RXRB RXRG FIZ1	3.99e-06	1160	43	12	GO:0030674
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	NR2F6 ZNF263 PRDM5 ZNF99 ZNF709 GFI1 NR2F1	4.99e-06	320	43	7	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	NR2F6 ZNF263 PRDM5 ZNF99 ZNF709 GFI1 NR2F1	5.64e-06	326	43	7	GO:0001217
GeneOntologyMolecularFunction	nuclear steroid receptor activity	RXRA RXRB RXRG	2.07e-05	25	43	3	GO:0003707
GeneOntologyMolecularFunction	transcription coactivator activity	KMT2E KAT6B CEBPZ RXRB FIZ1	4.67e-04	303	43	5	GO:0003713
GeneOntologyMolecularFunction	nuclear vitamin D receptor binding	RXRA RXRB	6.78e-04	18	43	2	GO:0042809
GeneOntologyMolecularFunction	methyltransferase activity	PRDM10 KMT2E PRDM5 PRDM14	1.12e-03	213	43	4	GO:0008168
GeneOntologyMolecularFunction	transcription coregulator activity	KMT2E KAT6B CEBPZ ZNF653 RXRB FIZ1	1.22e-03	562	43	6	GO:0003712
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	PRDM10 KMT2E PRDM5 PRDM14	1.35e-03	224	43	4	GO:0016741
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	RXRA RXRB	2.43e-03	34	43	2	GO:0046966
GeneOntologyMolecularFunction	zinc ion binding	NR2F6 ZMYM1 ENPP1 RXRA NR2F1 RXRB RXRG	2.72e-03	891	43	7	GO:0008270
GeneOntologyMolecularFunction	chromatin binding	KAT6B PRDM14 RXRA RXRB MAZ ZNF445	4.78e-03	739	43	6	GO:0003682
GeneOntologyMolecularFunction	chromatin DNA binding	PRDM14 RXRA RXRB	5.55e-03	167	43	3	GO:0031490
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	RXRA RXRB	6.26e-03	55	43	2	GO:0042974
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	PRDM5 ZNF653 RXRA RXRB FIZ1	7.98e-03	582	43	5	GO:0140297
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ZNF263 PRDM10 ZNF225 KAT6B PRDM5 ZNF99 CEBPZ RXRA ZNF840P NR2F1 RXRB RXRG MAZ ZNF197 FIZ1 SP7 ZNF445	8.68e-10	1390	43	17	GO:0045944
GeneOntologyBiologicalProcess	diphosphate metabolic process	ENPP1 SP7	4.23e-05	5	43	2	GO:0071344
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	NR2F6 ZNF263 PRDM5 ZNF99 PRDM14 ZNF653 RXRA GFI1 NR2F1 MAZ	4.73e-05	1053	43	10	GO:0000122
GeneOntologyBiologicalProcess	positive regulation of vitamin D receptor signaling pathway	RXRA RXRB	6.33e-05	6	43	2	GO:0070564
GeneOntologyBiologicalProcess	retinoic acid receptor signaling pathway	RXRA RXRB RXRG	6.77e-05	38	43	3	GO:0048384
GeneOntologyBiologicalProcess	cementum mineralization	ENPP1 SP7	8.86e-05	7	43	2	GO:0071529
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	NR2F6 ZNF263 KAT6B PRDM5 ZNF99 PRDM14 ZNF653 RXRA GFI1 NR2F1 MAZ	1.02e-04	1399	43	11	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	NR2F6 ZNF263 KAT6B PRDM5 ZNF99 PRDM14 ZNF653 RXRA GFI1 NR2F1 MAZ	1.12e-04	1413	43	11	GO:1902679
GeneOntologyBiologicalProcess	mRNA transcription by RNA polymerase II	ENPP1 RXRA RXRB	1.74e-04	52	43	3	GO:0042789
GeneOntologyBiologicalProcess	regulation of vitamin D receptor signaling pathway	RXRA RXRB	1.89e-04	10	43	2	GO:0070562
GeneOntologyBiologicalProcess	intracellular receptor signaling pathway	RNF34 NR2F6 RXRA NR2F1 RXRB RXRG	2.10e-04	416	43	6	GO:0030522
GeneOntologyBiologicalProcess	mRNA transcription	ENPP1 RXRA RXRB	2.28e-04	57	43	3	GO:0009299
GeneOntologyBiologicalProcess	vitamin D receptor signaling pathway	RXRA RXRB	2.77e-04	12	43	2	GO:0070561
GeneOntologyBiologicalProcess	regulation of myelination	RXRA RXRB RXRG	3.68e-04	67	43	3	GO:0031641
Domain	ZINC_FINGER_C2H2_2	ZNF611 ZNF432 BNC1 ZNF561 ZNF263 ZNF182 PRDM10 CPXCR1 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 TSHZ2 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	8.37e-23	775	42	24	PS50157
Domain	Znf_C2H2-like	ZNF611 ZNF432 BNC1 ZNF561 ZNF263 ZNF182 PRDM10 CPXCR1 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 TSHZ2 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	1.57e-22	796	42	24	IPR015880
Domain	Znf_C2H2	ZNF611 ZNF432 BNC1 ZNF561 ZNF263 ZNF182 PRDM10 CPXCR1 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 TSHZ2 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	2.05e-22	805	42	24	IPR007087
Domain	ZnF_C2H2	ZNF611 ZNF432 BNC1 ZNF561 ZNF263 ZNF182 PRDM10 CPXCR1 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 TSHZ2 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	2.24e-22	808	42	24	SM00355
Domain	ZINC_FINGER_C2H2_1	ZNF611 ZNF432 BNC1 ZNF561 ZNF263 ZNF182 PRDM10 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 TSHZ2 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	2.67e-21	777	42	23	PS00028
Domain	zf-C2H2	ZNF611 ZNF432 BNC1 ZNF561 ZNF263 ZNF182 PRDM10 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 TSHZ2 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	6.21e-21	693	42	22	PF00096
Domain	-	ZNF611 ZNF432 ZNF561 ZNF263 ZNF182 PRDM10 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	1.15e-19	679	42	21	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF611 ZNF432 ZNF561 ZNF263 ZNF182 PRDM10 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	1.80e-19	694	42	21	IPR013087
Domain	zf-C2H2_6	ZNF611 ZNF432 ZNF561 ZNF182 PRDM10 ZNF225 ZNF560 PRDM5 ZNF99 ZNF532 ZNF709 GFI1 ZNF197 ZNF445	3.74e-15	314	42	14	PF13912
Domain	KRAB	ZNF611 ZNF432 ZNF561 ZNF263 ZNF182 ZNF225 ZNF519 ZNF560 ZNF99 ZNF709 ZNF197 ZNF445	1.35e-11	358	42	12	PS50805
Domain	KRAB	ZNF611 ZNF432 ZNF561 ZNF263 ZNF182 ZNF225 ZNF519 ZNF560 ZNF99 ZNF709 ZNF197 ZNF445	1.35e-11	358	42	12	PF01352
Domain	KRAB	ZNF611 ZNF432 ZNF561 ZNF263 ZNF182 ZNF225 ZNF519 ZNF560 ZNF99 ZNF709 ZNF197 ZNF445	1.92e-11	369	42	12	SM00349
Domain	KRAB	ZNF611 ZNF432 ZNF561 ZNF263 ZNF182 ZNF225 ZNF519 ZNF560 ZNF99 ZNF709 ZNF197 ZNF445	1.98e-11	370	42	12	IPR001909
Domain	zf-C4	NR2F6 RXRA NR2F1 RXRB RXRG	5.76e-08	46	42	5	PF00105
Domain	NUCLEAR_REC_DBD_1	NR2F6 RXRA NR2F1 RXRB RXRG	5.76e-08	46	42	5	PS00031
Domain	Znf_hrmn_rcpt	NR2F6 RXRA NR2F1 RXRB RXRG	5.76e-08	46	42	5	IPR001628
Domain	Nuclear_hrmn_rcpt	NR2F6 RXRA NR2F1 RXRB RXRG	5.76e-08	46	42	5	IPR001723
Domain	ZnF_C4	NR2F6 RXRA NR2F1 RXRB RXRG	5.76e-08	46	42	5	SM00399
Domain	NUCLEAR_REC_DBD_2	NR2F6 RXRA NR2F1 RXRB RXRG	5.76e-08	46	42	5	PS51030
Domain	-	NR2F6 RXRA NR2F1 RXRB RXRG	6.43e-08	47	42	5	1.10.565.10
Domain	Nucl_hrmn_rcpt_lig-bd	NR2F6 RXRA NR2F1 RXRB RXRG	7.17e-08	48	42	5	IPR000536
Domain	Hormone_recep	NR2F6 RXRA NR2F1 RXRB RXRG	7.17e-08	48	42	5	PF00104
Domain	HOLI	NR2F6 RXRA NR2F1 RXRB RXRG	7.17e-08	48	42	5	SM00430
Domain	-	NR2F6 RXRA NR2F1 RXRB RXRG	1.73e-07	57	42	5	3.30.50.10
Domain	Znf_NHR/GATA	NR2F6 RXRA NR2F1 RXRB RXRG	1.89e-07	58	42	5	IPR013088
Domain	Znf_FYVE_PHD	RNF34 RPH3AL KMT2E KAT6B PRDM14 FGD3	8.91e-07	147	42	6	IPR011011
Domain	Retinoid-X_rcpt/HNF4	RXRA RXRB RXRG	1.26e-06	10	42	3	IPR000003
Domain	SET_dom	PRDM10 KMT2E PRDM5 PRDM14	4.72e-06	50	42	4	IPR001214
Domain	SET	PRDM10 KMT2E PRDM5 PRDM14	4.72e-06	50	42	4	PS50280
Domain	Nuc_recep-AF1	RXRA RXRG	4.94e-06	2	42	2	IPR021780
Domain	Nuc_recep-AF1	RXRA RXRG	4.94e-06	2	42	2	PF11825
Domain	COUP_TF	NR2F6 NR2F1	4.92e-05	5	42	2	IPR003068
Domain	Znf_FYVE	RNF34 RPH3AL FGD3	8.44e-05	38	42	3	IPR000306
Domain	ZF_FYVE	RNF34 RPH3AL FGD3	9.86e-05	40	42	3	PS50178
Domain	SET	KMT2E PRDM5 PRDM14	1.06e-04	41	42	3	PF00856
Domain	SET	KMT2E PRDM5 PRDM14	1.50e-04	46	42	3	SM00317
Domain	SCAN	ZNF263 ZNF197 ZNF445	2.70e-04	56	42	3	SM00431
Domain	SCAN_BOX	ZNF263 ZNF197 ZNF445	2.99e-04	58	42	3	PS50804
Domain	SCAN	ZNF263 ZNF197 ZNF445	2.99e-04	58	42	3	PF02023
Domain	SCAN_dom	ZNF263 ZNF197 ZNF445	2.99e-04	58	42	3	IPR003309
Domain	Retrov_capsid_C	ZNF263 ZNF197 ZNF445	3.15e-04	59	42	3	IPR008916
Domain	zf-C2H2_jaz	PRDM10 PRDM5	1.11e-03	22	42	2	PF12171
Domain	Znf_C2H2_jaz	PRDM10 PRDM5	1.11e-03	22	42	2	IPR022755
Domain	Znf_FYVE-rel	RPH3AL FGD3	2.65e-03	34	42	2	IPR017455
Domain	-	RNF34 RPH3AL KMT2E KAT6B FGD3	3.21e-03	449	42	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	RNF34 RPH3AL KMT2E KAT6B FGD3	3.53e-03	459	42	5	IPR013083
Domain	PHD	KMT2E KAT6B	1.23e-02	75	42	2	PF00628
Domain	Znf_PHD-finger	KMT2E KAT6B	1.36e-02	79	42	2	IPR019787
Domain	PHD	KMT2E KAT6B	1.71e-02	89	42	2	SM00249
Domain	Znf_PHD	KMT2E KAT6B	1.78e-02	91	42	2	IPR001965
Domain	ZF_PHD_2	KMT2E KAT6B	1.93e-02	95	42	2	PS50016
Domain	ZF_PHD_1	KMT2E KAT6B	1.97e-02	96	42	2	PS01359
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF611 ZNF432 RNF34 ZNF561 NR2F6 ZNF263 ZNF225 ZNF519 ZNF560 ZNF99 ZNF709 RXRA NR2F1 RXRB RXRG ZNF197 SP7 ZNF445	1.65e-10	1387	33	18	M734
Pathway	WP_NUCLEAR_RECEPTORS	NR2F6 RXRA NR2F1 RXRB RXRG	2.43e-08	38	33	5	MM15865
Pathway	WP_NUCLEAR_RECEPTORS	NR2F6 RXRA NR2F1 RXRB RXRG	2.43e-08	38	33	5	M39657
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR2F6 RXRA NR2F1 RXRB RXRG	8.16e-08	48	33	5	MM14987
Pathway	KEGG_MEDICUS_VARIANT_PAX8_PPARG_FUSION_TO_PPARG_MEDIATED_TRANSCRIPTION	RXRA RXRB RXRG	1.17e-07	5	33	3	M49023
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR2F6 RXRA NR2F1 RXRB RXRG	1.36e-07	53	33	5	M8276
Pathway	WP_VITAMIN_A1_AND_A5X_PATHWAYS	RXRA RXRB RXRG	2.33e-07	6	33	3	M48097
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	RNF34 NR2F6 ZNF263 ZNF519 ZNF99 ZNF709 RXRA NR2F1 RXRB RXRG ZNF445	7.49e-07	768	33	11	MM14851
Pathway	KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY	RXRA RXRB RXRG	9.72e-07	9	33	3	M47629
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	RNF34 NR2F6 ZNF263 ZNF519 ZNF99 ZNF709 RXRA NR2F1 RXRB RXRG ZNF445	1.21e-05	1022	33	11	MM15436
Pathway	PID_RXR_VDR_PATHWAY	RXRA RXRB RXRG	2.93e-05	26	33	3	M162
Pathway	KEGG_THYROID_CANCER	RXRA RXRB RXRG	4.10e-05	29	33	3	M523
Pathway	PID_RETINOIC_ACID_PATHWAY	RXRA RXRB RXRG	4.55e-05	30	33	3	M207
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_GLUCONEOGENESIS	RXRA RXRB	5.29e-05	5	33	2	M29812
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_LIMIT_CHOLESTEROL_UPTAKE	RXRA RXRB	5.29e-05	5	33	2	M29791
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_TRIGLYCERIDE_LIPOLYSIS_IN_ADIPOSE	RXRA RXRB	5.29e-05	5	33	2	M29792
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS	RXRA RXRB	7.92e-05	6	33	2	MM15663
Pathway	WP_VITAMIN_A_AND_CAROTENOID_METABOLISM	RXRA RXRB RXRG	1.35e-04	43	33	3	M39554
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RXRA RXRB RXRG	1.35e-04	43	33	3	M27443
Pathway	WP_RETINOL_METABOLISM	RXRA RXRB RXRG	1.45e-04	44	33	3	MM15851
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	RXRA RXRB RXRG	1.66e-04	46	33	3	M239
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS	RXRA RXRB	1.89e-04	9	33	2	M29809
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS	RXRA RXRB	1.89e-04	9	33	2	M29789
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RXRA RXRB RXRG	2.00e-04	49	33	3	MM15186
Pathway	WP_VITAMIN_D_METABOLISM	RXRA RXRB	2.36e-04	10	33	2	M39352
Pathway	PID_AR_TF_PATHWAY	RXRA RXRB RXRG	2.53e-04	53	33	3	M151
Pathway	KEGG_NON_SMALL_CELL_LUNG_CANCER	RXRA RXRB RXRG	2.67e-04	54	33	3	M19818
Pathway	REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING	RXRA RXRB	4.08e-04	13	33	2	MM15622
Pathway	WP_PPAR_SIGNALING	RXRA RXRB RXRG	5.06e-04	67	33	3	M39553
Pathway	KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	RXRA RXRB RXRG	5.06e-04	67	33	3	M10462
Pathway	KEGG_PPAR_SIGNALING_PATHWAY	RXRA RXRB RXRG	5.51e-04	69	33	3	M13088
Pathway	WP_NONSMALL_CELL_LUNG_CANCER	RXRA RXRB RXRG	6.24e-04	72	33	3	M39738
Pathway	WP_PPAR_SIGNALING_PATHWAY	RXRA RXRB RXRG	6.50e-04	73	33	3	MM15995
Pathway	WP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3	RXRA RXRB RXRG	7.04e-04	75	33	3	M39568
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	RXRA RXRB RXRG	9.79e-04	84	33	3	M3228
Pathway	WP_SMALL_CELL_LUNG_CANCER	RXRA RXRB RXRG	1.44e-03	96	33	3	M39834
Pathway	REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX	RXRA RXRB	3.36e-03	37	33	2	M29790
Pathway	WP_ADIPOGENESIS	RXRA NR2F1 RXRG	3.49e-03	131	33	3	M39505
Pathway	WP_ADIPOGENESIS_GENES	RXRA NR2F1 RXRG	3.96e-03	137	33	3	MM15970
Pathway	REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING	RXRA RXRB	5.38e-03	47	33	2	M29777
Pubmed	Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.	NR2F6 RXRA NR2F1 RXRB RXRG	1.36e-14	6	43	5	7947324
Pubmed	A census of human transcription factors: function, expression and evolution.	BNC1 NR2F6 ZNF182 PRDM5 TSHZ2 CEBPZ ZNF653 RXRA NR2F1 RXRB RXRG MAZ ZNF197 SP7	2.40e-12	908	43	14	19274049
Pubmed	A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells.	RXRA NR2F1 RXRB RXRG	2.54e-10	9	43	4	7823919
Pubmed	Retinoid X receptors: X-ploring their (patho)physiological functions.	RXRA RXRB RXRG	1.76e-09	3	43	3	15608692
Pubmed	Chromosomal localization of the human retinoid X receptors.	RXRA RXRB RXRG	1.76e-09	3	43	3	8034312
Pubmed	Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition.	RXRA RXRB RXRG	1.76e-09	3	43	3	7831303
Pubmed	Retinoid receptors trigger neuritogenesis in retinal degenerations.	RXRA RXRB RXRG	1.76e-09	3	43	3	21940995
Pubmed	The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.	RXRA RXRB RXRG	1.76e-09	3	43	3	11839661
Pubmed	Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.	RXRA RXRB RXRG	1.76e-09	3	43	3	1312497
Pubmed	Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.	RXRA RXRB RXRG	1.76e-09	3	43	3	7980510
Pubmed	Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.	RXRA RXRB RXRG	1.76e-09	3	43	3	12514092
Pubmed	Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.	RXRA RXRB RXRG	1.76e-09	3	43	3	11053444
Pubmed	RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.	RXRA RXRB RXRG	1.76e-09	3	43	3	8799145
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	NR2F6 ZNF263 ZNF519 PRDM5 CEBPZ PRDM14 RXRA GFI1 RXRB RXRG SP7	6.78e-09	877	43	11	20211142
Pubmed	Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.	RXRA RXRB RXRG	7.04e-09	4	43	3	9804293
Pubmed	Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.	RXRA RXRB RXRG	7.04e-09	4	43	3	1310259
Pubmed	Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice.	RXRA RXRB RXRG	7.04e-09	4	43	3	10079186
Pubmed	Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.	RXRA RXRB RXRG	7.04e-09	4	43	3	26355550
Pubmed	Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.	RXRA RXRB RXRG	7.04e-09	4	43	3	19686701
Pubmed	Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.	RXRA NR2F1 RXRB RXRG	1.46e-08	22	43	4	10753524
Pubmed	Retinoic acid signaling is necessary for the development of the organ of Corti.	RXRA RXRB RXRG	1.76e-08	5	43	3	10452855
Pubmed	Developmental expression of murine retinoid X receptor (RXR) genes.	RXRA RXRB RXRG	1.76e-08	5	43	3	8199055
Pubmed	Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein.	RXRA NR2F1 RXRB	1.76e-08	5	43	3	1331778
Pubmed	Peroxisome proliferator-activated receptors modulate proliferation and angiogenesis in human endometrial carcinoma.	RXRA RXRB RXRG	3.51e-08	6	43	3	22205725
Pubmed	The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.	RXRA RXRB RXRG	3.51e-08	6	43	3	9806918
Pubmed	Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.	RXRA RXRB RXRG	3.51e-08	6	43	3	11328745
Pubmed	TGIF inhibits retinoid signaling.	RXRA RXRB RXRG	3.51e-08	6	43	3	16428452
Pubmed	A genetic dissection of the retinoid signalling pathway in the mouse.	RXRA RXRB RXRG	3.51e-08	6	43	3	10604193
Pubmed	The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains.	RXRA RXRB RXRG	3.51e-08	6	43	3	9153406
Pubmed	Spatial distributions of retinoic acid receptor gene transcripts in the prenatal mouse inner ear.	RXRA RXRB RXRG	3.51e-08	6	43	3	9548551
Pubmed	Functional specificity of the two retinoic acid receptor RAR and RXR families in myogenesis.	RXRA RXRB RXRG	3.51e-08	6	43	3	9464546
Pubmed	Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.	RXRA RXRB RXRG	3.51e-08	6	43	3	9075714
Pubmed	Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.	RXRA RXRB RXRG	3.51e-08	6	43	3	20557428
Pubmed	RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells.	RXRA RXRB RXRG	3.51e-08	6	43	3	8801169
Pubmed	A decade of molecular biology of retinoic acid receptors.	RXRA RXRB RXRG	3.51e-08	6	43	3	8801176
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF263 KAT6B PRDM5 ZNF99 ZNF653 RXRA NR2F1 RXRB FIZ1 ZNF445	4.15e-08	808	43	10	20412781
Pubmed	Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors.	RXRA RXRB RXRG	6.14e-08	7	43	3	17195188
Pubmed	Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes.	RXRA RXRB RXRG	6.14e-08	7	43	3	9428411
Pubmed	Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.	RXRA RXRB RXRG	6.14e-08	7	43	3	11493527
Pubmed	The structure of the nuclear hormone receptors.	RXRA RXRB RXRG	6.14e-08	7	43	3	10406480
Pubmed	Analysis of the factors involved in the retinoic acid-induced differentiation of a retinoid-hypersensitive embryonal carcinoma cell mutant.	RXRA RXRB RXRG	6.14e-08	7	43	3	8299717
Pubmed	Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions.	RXRA RXRB RXRG	6.14e-08	7	43	3	12360493
Pubmed	Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.	RXRA RXRB RXRG	6.14e-08	7	43	3	15635645
Pubmed	Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.	RXRA RXRB RXRG	6.14e-08	7	43	3	8090775
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF611 ZNF432 ZNF561 ZNF182 ZNF197 ZNF445	9.50e-08	181	43	6	37372979
Pubmed	Dorsal and ventral rentinoic territories defined by retinoic acid synthesis, break-down and nuclear receptor expression.	RXRA RXRB RXRG	9.82e-08	8	43	3	10490294
Pubmed	Expression of nuclear retinoic acid receptors during mouse odontogenesis.	RXRA RXRB RXRG	9.82e-08	8	43	3	7988794
Pubmed	Retinoids and adipose tissues: metabolism, cell differentiation and gene expression.	RXRA RXRB RXRG	9.82e-08	8	43	3	10094571
Pubmed	Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.	RXRA RXRB RXRG	9.82e-08	8	43	3	16043864
Pubmed	Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.	RXRA RXRB RXRG	9.82e-08	8	43	3	17124491
Pubmed	Enhancer activation requires trans-recruitment of a mega transcription factor complex.	RXRA RXRB RXRG	2.10e-07	10	43	3	25303530
Pubmed	Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter.	RXRA RXRB RXRG	2.88e-07	11	43	3	29093497
Pubmed	Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse.	RXRA RXRB RXRG	3.84e-07	12	43	3	9022057
Pubmed	Cholesterol and cholesterol plus DHA diet-induced gene expression and fatty acid changes in mouse eye and brain.	RXRA RXRB RXRG	3.84e-07	12	43	3	15589691
Pubmed	Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.	RXRA RXRB RXRG	3.84e-07	12	43	3	26427057
Pubmed	Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma.	RXRA RXRB RXRG	4.99e-07	13	43	3	1358808
Pubmed	Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.	RXRA RXRB RXRG	6.35e-07	14	43	3	18561907
Pubmed	Retinoic acid induces prostatic bud formation.	RXRA RXRB RXRG	6.35e-07	14	43	3	18393306
Pubmed	LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.	RXRA RXRB RXRG	6.35e-07	14	43	3	21923909
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	NR2F6 RXRA NR2F1 RXRB RXRG	6.49e-07	133	43	5	15604093
Pubmed	Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia.	RXRA RXRB RXRG	7.93e-07	15	43	3	19448158
Pubmed	Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta.	RXRA RXRB RXRG	9.75e-07	16	43	3	25577283
Pubmed	External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.	RXRA RXRB RXRG	9.75e-07	16	43	3	11795391
Pubmed	Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.	RXRA RXRB RXRG	1.18e-06	17	43	3	28291835
Pubmed	Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.	RXRA RXRB	1.49e-06	2	43	2	33246082
Pubmed	RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.	RXRA RXRB	1.49e-06	2	43	2	7926783
Pubmed	Endogenous retinoid X receptor ligands in mouse hematopoietic cells.	RXRA RXRB	1.49e-06	2	43	2	29089448
Pubmed	Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development.	RXRB RXRG	1.49e-06	2	43	2	9150186
Pubmed	The retinoid X receptors and their ligands.	RXRA RXRG	1.49e-06	2	43	2	22020178
Pubmed	Thyroid hormone resistance and increased metabolic rate in the RXR-gamma-deficient mouse.	RXRA RXRG	1.49e-06	2	43	2	10880050
Pubmed	Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice.	RXRB RXRG	1.49e-06	2	43	2	20620876
Pubmed	Three retinoid X receptor gene polymorphisms in plaque psoriasis and psoriasis guttata.	RXRA RXRB	1.49e-06	2	43	2	17341859
Pubmed	Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin.	RXRA RXRB	1.49e-06	2	43	2	16199515
Pubmed	Transcriptional activation of ENPP1 by osterix in osteoblasts and osteocytes.	ENPP1 SP7	1.49e-06	2	43	2	30047979
Pubmed	Association between functional genetic variants in retinoid X receptor-α/γ and the risk of gestational diabetes mellitus in a southern Chinese population.	RXRA RXRG	1.49e-06	2	43	2	34633445
Pubmed	Retinoid-X-receptors (α/β) in melanocytes modulate innate immune responses and differentially regulate cell survival following UV irradiation.	RXRA RXRB	1.49e-06	2	43	2	24810760
Pubmed	Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling.	RXRA NR2F1	1.49e-06	2	43	2	1311101
Pubmed	Limited degradation of retinoid X receptor by calpain.	RXRA RXRB	1.49e-06	2	43	2	8780715
Pubmed	Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cells.	RXRA RXRB	1.49e-06	2	43	2	20798333
Pubmed	A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.	RXRA RXRB	1.49e-06	2	43	2	19255444
Pubmed	Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity.	RXRA RXRB	1.49e-06	2	43	2	22316320
Pubmed	Retinoid X receptor γ up-regulation is correlated with dedifferentiation of tumor cells and lymph node metastasis in papillary thyroid carcinoma.	RXRA RXRG	1.49e-06	2	43	2	21355951
Pubmed	Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other.	NR2F6 NR2F1	1.49e-06	2	43	2	2905047
Pubmed	Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning.	RXRA RXRB RXRG	1.98e-06	20	43	3	19605690
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KAT6B ZNF532 RXRA NR2F1 RXRB RXRG SP7 ZNF445	2.21e-06	709	43	8	22988430
Pubmed	A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.	NR2F6 RXRA NR2F1	2.67e-06	22	43	3	23975195
Pubmed	Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.	PRDM10 PRDM5 PRDM14	2.67e-06	22	43	3	19050759
Pubmed	Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.	RXRA RXRB RXRG	3.06e-06	23	43	3	19737349
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	NR2F6 ZNF263 RXRA GFI1 NR2F1 RXRB RXRG	4.36e-06	544	43	7	28473536
Pubmed	Nuclear orphan receptors regulate transcription of the gene for the human luteinizing hormone receptor.	NR2F6 NR2F1	4.48e-06	3	43	2	10644740
Pubmed	Expression of a novel murine homeobox gene in the developing cerebellar external granular layer during its proliferation.	RXRA RXRG	4.48e-06	3	43	2	8901052
Pubmed	Unique response pathways are established by allosteric interactions among nuclear hormone receptors.	RXRA RXRB	4.48e-06	3	43	2	7758108
Pubmed	The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.	RXRA RXRB	4.48e-06	3	43	2	9727070
Pubmed	Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.	ADAM10 RXRA	4.48e-06	3	43	2	19144697
Pubmed	Differential 9-cis-retinoic acid-dependent transcriptional activation by murine retinoid X receptor alpha (RXR alpha) and RXR beta. Role of cell type and RXR domains.	RXRA RXRB	4.48e-06	3	43	2	8631847
Pubmed	Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.	RXRA RXRB	4.48e-06	3	43	2	19188585
Pubmed	An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita.	RXRA RXRB	4.48e-06	3	43	2	7990953
Pubmed	Genetic variants in vitamin D signaling pathways and risk of gestational diabetes mellitus.	RXRA RXRG	4.48e-06	3	43	2	27636996
Pubmed	A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits.	RPH3AL CEBPZ	4.48e-06	3	43	2	12446671
Pubmed	Vitamin-D receptor agonist calcitriol reduces calcification in vitro through selective upregulation of SLC20A2 but not SLC20A1 or XPR1.	RXRA RXRB	4.48e-06	3	43	2	27184385
Interaction	NR2F6 interactions	NR2F6 RXRA RXRG SP7	2.50e-06	46	42	4	int:NR2F6
Interaction	RXRG interactions	NR2F6 CEBPZ RXRA RXRG	2.72e-06	47	42	4	int:RXRG
Interaction	ZNF232 interactions	ZNF263 ZMYM1 ZNF197 ZNF445	4.10e-06	52	42	4	int:ZNF232
Interaction	RARG interactions	NR2F6 RXRA RXRB RXRG	6.37e-06	58	42	4	int:RARG
Interaction	MPPED2 interactions	NR2F6 NR2F1 RXRG	1.26e-05	22	42	3	int:MPPED2
Interaction	NCOA1 interactions	NR2F6 RXRA NR2F1 RXRB SP7	1.28e-05	146	42	5	int:NCOA1
Interaction	NR1H4 interactions	RXRA RXRB RXRG	4.00e-05	32	42	3	int:NR1H4
Interaction	THRA interactions	RXRA NR2F1 RXRB RXRG	8.30e-05	111	42	4	int:THRA
Interaction	TGIF1 interactions	RXRA RXRB RXRG	8.49e-05	41	42	3	int:TGIF1
Interaction	NSD1 interactions	NR2F6 ZNF653 RXRA NR2F1	1.09e-04	119	42	4	int:NSD1
Interaction	DLX4 interactions	ZNF263 SP7	1.18e-04	8	42	2	int:DLX4
Interaction	RARB interactions	RXRA RXRB RXRG	1.20e-04	46	42	3	int:RARB
Interaction	NR1I2 interactions	RXRA RXRB RXRG	1.36e-04	48	42	3	int:NR1I2
Interaction	NOTCH2 interactions	ZNF611 ZNF263 ZNF709 MAZ FIZ1 ZNF445	2.28e-04	423	42	6	int:NOTCH2
Interaction	NR1H3 interactions	RXRA RXRB RXRG	2.40e-04	58	42	3	int:NR1H3
Interaction	ZSCAN20 interactions	ZNF263 ZNF197 ZNF445	3.36e-04	65	42	3	int:ZSCAN20
Interaction	NR1H2 interactions	RXRA RXRB RXRG	3.84e-04	68	42	3	int:NR1H2
Interaction	RXRA interactions	NR2F6 RXRA NR2F1 RXRG	4.17e-04	169	42	4	int:RXRA
Interaction	POU2F1 interactions	PRDM5 RXRA NR2F1 SP7	4.75e-04	175	42	4	int:POU2F1
Cytoband	19p13.2	ZNF561 ZNF560 ZNF709 ZNF653	6.39e-05	229	43	4	19p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	ZNF561 NR2F6 ZNF560 ZNF709 CSNK1G2 ZNF653	9.48e-05	797	43	6	chr19p13
Cytoband	19q13.41	ZNF611 ZNF432	2.46e-03	78	43	2	19q13.41
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF611 ZNF432 BNC1 ZNF561 ZNF263 ZNF182 PRDM10 ZNF225 ZNF519 ZNF560 PRDM5 ZNF99 ZNF532 TSHZ2 ZNF709 PRDM14 ZNF653 GFI1 MAZ ZNF197 FIZ1 SP7 ZNF445	3.73e-23	718	38	23	28
GeneFamily	Nuclear hormone receptors	NR2F6 RXRA NR2F1 RXRB RXRG	5.56e-08	49	38	5	71
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM10 PRDM5 PRDM14	5.71e-06	17	38	3	1197
GeneFamily	PHD finger proteins	KMT2E KAT6B	1.53e-02	90	38	2	88
Drug	DR-0	NR2F6 RXRA NR2F1 RXRB RXRG	5.88e-09	35	43	5	CID010062716
Drug	Bexarotene	RXRA RXRB RXRG	6.27e-09	3	43	3	DB00307
Drug	2-hydroxyphytanic acid	RXRA RXRB RXRG	6.27e-09	3	43	3	ctd:C002585
Drug	AC1O5SBP	RXRA RXRB RXRG	6.27e-09	3	43	3	CID006439746
Drug	AGN 190727	RXRA RXRB RXRG	2.51e-08	4	43	3	CID006439768
Drug	7-methoxycitronellal	RXRA RXRB RXRG	6.26e-08	5	43	3	CID000019223
Drug	13,14-dihydroretinol	RXRA RXRB RXRG	6.26e-08	5	43	3	CID000446798
Drug	7-methoxycitronellic acid	RXRA RXRB RXRG	6.26e-08	5	43	3	CID000171516
Drug	Alitretinoin	RXRA RXRB RXRG	1.25e-07	6	43	3	DB00523
Drug	Adapalene	RXRA RXRB RXRG	1.25e-07	6	43	3	DB00210
Drug	Etretinate	RXRA RXRB RXRG	1.25e-07	6	43	3	DB00926
Drug	triphenyltin hydroxide	RXRA RXRB RXRG	1.25e-07	6	43	3	ctd:C007567
Drug	Acitretin	RXRA RXRB RXRG	2.18e-07	7	43	3	DB00459
Drug	AGN 191659	RXRA RXRB RXRG	2.18e-07	7	43	3	CID006366726
Drug	AGN 190121	RXRA RXRB RXRG	2.18e-07	7	43	3	CID006441236
Drug	HX 600	RXRA RXRB RXRG	3.49e-07	8	43	3	ctd:C104181
Drug	TTNN	RXRA RXRB RXRG	3.49e-07	8	43	3	CID000135754
Drug	AC1O5JP6	RXRA RXRB RXRG	3.49e-07	8	43	3	CID006435379
Drug	HX 630	RXRA RXRB RXRG	7.46e-07	10	43	3	ctd:C422175
Drug	diazepinylbenzoic acid	RXRA RXRB RXRG	7.46e-07	10	43	3	ctd:C438269
Drug	AGN 191701	RXRA RXRB RXRG	1.02e-06	11	43	3	CID006438168
Drug	UVI 3003	RXRA RXRB RXRG	1.02e-06	11	43	3	ctd:C525131
Drug	Musk T	RXRA RXRB RXRG	1.02e-06	11	43	3	CID000061014
Drug	di-n-propylphthalate	RXRA RXRB RXRG	1.36e-06	12	43	3	ctd:C106479
Drug	NSC46155	RXRA RXRB RXRG	1.36e-06	12	43	3	CID000457869
Drug	AC1L2E0P	NR2F6 KAT6B ZNF653 RXRA NR2F1 RXRB RXRG	1.61e-06	307	43	7	CID000019390
Drug	S-(+)-Methoprene	RXRA NR2F1 RXRB RXRG	1.70e-06	46	43	4	CID000038532
Drug	tazarotenic acid	RXRA RXRB RXRG	1.77e-06	13	43	3	CID000147525
Drug	GW2331	RXRA RXRB RXRG	1.77e-06	13	43	3	CID000657048
Drug	Cd2665	RXRA RXRB RXRG	1.77e-06	13	43	3	CID000216241
Drug	E-guggulsterone	NR2F6 RXRA NR2F1 RXRB RXRG	1.82e-06	108	43	5	CID006439929
Drug	Sulfonamides	RXRA RXRB RXRG	2.25e-06	14	43	3	ctd:D013449
Drug	AC1L1DMQ	RXRA RXRB RXRG	2.25e-06	14	43	3	CID000002418
Drug	phthalic acid	RXRA RXRB RXRG	4.19e-06	17	43	3	ctd:C032279
Drug	HX600	RXRA RXRB RXRG	5.02e-06	18	43	3	CID000128016
Drug	androst-2-en-3-ol	RXRA RXRB RXRG	5.02e-06	18	43	3	CID000166036
Drug	diheptyl phthalate	RXRA RXRB RXRG	8.15e-06	21	43	3	ctd:C089799
Drug	di-n-hexyl phthalate	RXRA RXRB RXRG	9.42e-06	22	43	3	ctd:C027387
Drug	adapalene	RXRA RXRB RXRG	9.42e-06	22	43	3	CID000060164
Drug	Ro 15-0778	RXRA RXRB RXRG	1.08e-05	23	43	3	CID006436116
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.29e-05	161	43	5	4768_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.37e-05	163	43	5	7453_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.37e-05	163	43	5	5594_DN
Drug	scoparone	RXRA RXRB RXRG	1.40e-05	25	43	3	CID000008417
Drug	AC1L1KPQ	RXRA NR2F1 RXRB RXRG	1.42e-05	78	43	4	CID000005602
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.45e-05	165	43	5	6085_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.45e-05	165	43	5	2835_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.49e-05	166	43	5	2247_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.49e-05	166	43	5	7324_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.54e-05	167	43	5	5217_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.58e-05	168	43	5	3868_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.58e-05	168	43	5	3395_DN
Drug	Prt-H	RXRA RXRB RXRG	1.58e-05	26	43	3	CID003050291
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.63e-05	169	43	5	5572_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.63e-05	169	43	5	5231_DN
Drug	T0901317	ADAM10 RXRA RXRB RXRG	1.65e-05	81	43	4	CID000447912
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.67e-05	170	43	5	7043_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.67e-05	170	43	5	5260_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.72e-05	171	43	5	7407_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.72e-05	171	43	5	2777_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.77e-05	172	43	5	3428_DN
Drug	AC1L2X6Z	RXRA RXRB RXRG	1.78e-05	27	43	3	CID000130325
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.82e-05	173	43	5	3243_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.87e-05	174	43	5	3462_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.87e-05	174	43	5	1659_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.87e-05	174	43	5	5945_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.87e-05	174	43	5	5580_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.87e-05	174	43	5	6493_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.92e-05	175	43	5	5935_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.92e-05	175	43	5	6891_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.92e-05	175	43	5	1014_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.98e-05	176	43	5	5976_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	1.98e-05	176	43	5	3312_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	2.03e-05	177	43	5	1645_DN
Drug	SR 11237	RXRA NR2F1	2.09e-05	4	43	2	ctd:C087130
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	2.09e-05	178	43	5	1672_DN
Drug	scriptaid; Down 200; 10uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	2.15e-05	179	43	5	6901_DN
Drug	SR-12813	RXRA RXRB RXRG	2.22e-05	29	43	3	CID000446313
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NR2F6 PRDM10 KAT6B RXRA SLC6A14	2.26e-05	181	43	5	7005_DN
Drug	AGN 193109	RXRA RXRB RXRG	2.72e-05	31	43	3	CID000177238
Drug	T0070907	RXRA RXRB RXRG	2.72e-05	31	43	3	CID002777391
Drug	TCPOBOP	ENPP1 RXRA RXRB RXRG	3.10e-05	95	43	4	CID000005382
Drug	CD367	RXRA RXRB RXRG	3.29e-05	33	43	3	CID000119342
Drug	AC1L3LFV	RXRA RXRB RXRG	3.29e-05	33	43	3	CID000091134
Drug	Retinoids	RXRA RXRB RXRG	3.60e-05	34	43	3	ctd:D012176
Drug	Ro 41-5253	RXRA RXRB RXRG	4.66e-05	37	43	3	CID005312120
Drug	CV-1	NR2F6 RXRA NR2F1 RXRB RXRG	4.93e-05	213	43	5	CID000130105
Drug	Methoprene	RXRA RXRB	5.20e-05	6	43	2	ctd:D008726
Drug	tazarotene	RXRA RXRB RXRG	5.90e-05	40	43	3	CID000005381
Drug	acyclic retinoid	RXRA RXRB RXRG	6.36e-05	41	43	3	CID006437836
Drug	vitamin D3 analog	RXRA RXRB RXRG	6.36e-05	41	43	3	CID006438384
Drug	AC1Q6CTU	RXRA NR2F1 RXRB RXRG	7.24e-05	118	43	4	CID000021362
Drug	AC1L1HRY	RXRA RXRB RXRG	8.42e-05	45	43	3	CID000004265
Drug	Etretinate-d3	RXRA RXRB RXRG	8.42e-05	45	43	3	CID000003312
Drug	vinylene	ZNF263 MAZ ZNF197 SP7 ZNF445	9.55e-05	245	43	5	CID000006326
Drug	Tretinoin	RXRB RXRG	9.69e-05	8	43	2	DB00755
Drug	diethyl phthalate	RXRA RXRB RXRG	1.02e-04	48	43	3	ctd:C007379
Drug	di-n-pentyl phthalate	RXRA RXRB RXRG	1.23e-04	51	43	3	ctd:C034171
Drug	LG 268	RXRA RXRG	1.55e-04	10	43	2	ctd:C423914
Drug	AGN 194204	RXRA GFI1 RXRB RXRG	2.46e-04	162	43	4	ctd:C430898
Disease	Malignant neoplasm of breast	ZNF432 NR2F6 COL19A1 KAT6B ZNF532 ADAM10 NR2F1 RXRB	9.84e-05	1074	41	8	C0006142
Disease	Mammary Neoplasms, Human	ZNF432 NR2F6 ADAM10 NR2F1 RXRB	7.73e-04	525	41	5	C1257931
Disease	Mammary Carcinoma, Human	ZNF432 NR2F6 ADAM10 NR2F1 RXRB	7.73e-04	525	41	5	C4704874
Disease	Mammary Neoplasms	ZNF432 NR2F6 ADAM10 NR2F1 RXRB	7.86e-04	527	41	5	C1458155
Disease	Breast Carcinoma	ZNF432 NR2F6 ADAM10 NR2F1 RXRB	8.62e-04	538	41	5	C0678222

Protein segments in the cluster

Peptide	Gene	Start	Entry
CPTFKKFKRNDDECR	CATSPER3	26	Q86XQ3
AFKSKSEKCRDDSDC	ADAM10	516	O14672
GTKKGRVFCTACEKT	BNC1	351	Q01954
KFCKSTDTKGKCRFR	CPXCR1	216	Q8N123
FTCEGCKSFFKRSIR	NR2F6	71	P10588
FTCEGCKSFFKRSVR	NR2F1	101	P10589
RFVCKADSCGKRLKS	PRDM5	261	Q9NQX1
CSFCLGTKESNREKK	KAT6B	216	Q8WYB5
ECREFSATKKFKRSV	KIAA1107	911	Q9UPP5
SFDCKICGKSFKRSS	GFI1	311	Q99684
ETKCCCFFKRRKRKS	CSNK1G2	396	P78368
SFFCRIKSCKISVKE	ARNTL2	281	Q8WYA1
CKKAFREGSRKSSRV	KMT2E	241	Q8IZD2
FKCEKCEAAFATKDR	MAZ	366	P56270
CAKEVKSCKGRCFER	ENPP1	101	P22413
RDKEKQSCKSCGETF	FGD3	531	Q5JSP0
DFLCSTCGKQFKRKD	PRDM10	671	Q9NQV6
RRAFCESDKTCFKLG	COL19A1	66	Q14993
KKIFGCSECEKLFRS	FIZ1	411	Q96SL8
SCEGCKGFFKRTVRK	RXRA	151	P19793
FCFFRTCVKKKDVES	CEBPZ	466	Q03701
GSSSVFCKDCRKKVC	RPH3AL	106	Q9UNE2
KFPCSLCKRSFEKRD	PRDM14	431	Q9GZV8
SCEGCKGFFKRTIRK	RXRB	221	P28702
KGEKSFECKECGRSF	ZNF561	276	Q8N587
KCEECGKAFKRFSAL	ZNF99	426	A8MXY4
VSDRKCKVCAKTFET	ZNF532	1261	Q9HCE3
REFTCETCGKSFKRK	ZNF653	526	Q96CK0
FTCDRCGKRFEKLDS	ZNF653	586	Q96CK0
EKPFECTACRKTFSK	ZNF182	231	P17025
ECDKCRKSFTSKRNL	ZNF197	931	O14709
KFFKCKECGKAFTRS	ZNF519	486	Q8TB69
FKCKECGKAFNRRST	ZNF519	516	Q8TB69
VCKACGLSFSVFRKK	RNF34	61	Q969K3
EKKFTCLLCSKRFTR	SP7	351	Q8TDD2
KKSFICSSCKKTFVR	ZNF840P	386	A6NDX5
CEGCKGFFKRTIRKD	RXRG	156	P48443
DSKFKCKLCCRTFVS	TSHZ2	991	Q9NRE2
ECKECGKRFSFRSSF	ZNF709	141	Q8N972
KPFKCDICCKSFRSR	ZNF225	286	Q9UK10
TRERPFKCSKCGKTF	ZNF445	1001	P59923
KREKSFICSECGKVF	ZNF432	256	O94892
KCDECEKVFSRKSSL	ZNF611	511	Q8N823
GKSRSIKKSCCADFE	ZMYM1	451	Q5SVZ6
CPSFFKCREKEKVSA	SLC6A14	6	Q9UN76
KCKECGKAFRTSSGR	ZNF560	741	Q96MR9
EKKLFECLTCGKSFR	ZNF263	571	O14978