Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

DCAF1 TNIK PLK2 MAK MAP4K3 PDK2 CDK19 MAP3K4 NEK3 MAST4 BUB1 TOP1

1.03e-0544611512GO:0004674
GeneOntologyMolecularFunctionkinase activity

DCAF1 TNIK PLK2 MAK MAP4K3 PDK2 CDK19 DGKB MAP3K4 CKB NEK3 MAST4 BUB1 MERTK TOP1

3.28e-0576411515GO:0016301
GeneOntologyMolecularFunctionprotein kinase activity

DCAF1 TNIK PLK2 MAK MAP4K3 PDK2 CDK19 MAP3K4 NEK3 MAST4 BUB1 MERTK TOP1

4.23e-0560011513GO:0004672
GeneOntologyMolecularFunctionprotein serine kinase activity

DCAF1 TNIK PLK2 MAK MAP4K3 CDK19 MAP3K4 NEK3 MAST4 BUB1

4.78e-0536311510GO:0106310
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

DCAF1 TNIK PLK2 MAK MAP4K3 PDK2 CDK19 DGKB MAP3K4 NEK3 MAST4 BUB1 MERTK TOP1

5.77e-0570911514GO:0016773
GeneOntologyMolecularFunctionhistone H2A kinase activity

DCAF1 BUB1

9.83e-0531152GO:0140995
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

DCAF1 TNIK PLK2 MAK MAP4K3 PDK2 CDK19 DGKB MAP3K4 CKB NEK3 MAST4 BUB1 MERTK TOP1

3.17e-0493811515GO:0016772
GeneOntologyBiologicalProcessneuron projection development

VAPA TNIK CACNA1A EVL PLK2 ABI1 NEDD4L ANK3 BLOC1S4 LZTS3 GATA3 MAPK8IP3 NEK3 IFRD1 MYPN SLIT1 VASH2 NUMB VPS13B USP33

3.44e-05128511720GO:0031175
GeneOntologyBiologicalProcessneuron projection morphogenesis

TNIK CACNA1A EVL ABI1 NEDD4L ANK3 LZTS3 GATA3 MAPK8IP3 NEK3 IFRD1 MYPN SLIT1 NUMB USP33

4.85e-0580211715GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

TNIK CACNA1A EVL ABI1 NEDD4L ANK3 LZTS3 GATA3 MAPK8IP3 NEK3 IFRD1 MYPN SLIT1 NUMB USP33

6.15e-0581911715GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

TNIK CACNA1A EVL ABI1 NEDD4L ANK3 LZTS3 GATA3 MAPK8IP3 NEK3 IFRD1 MYPN SLIT1 NUMB USP33

6.77e-0582611715GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

TNIK CACNA1A EVL ABI1 NEDD4L ANK3 LZTS3 GATA3 MAPK8IP3 IFRD1 MYPN SLIT1 NUMB USP33

8.76e-0574811714GO:0048667
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DCAF1 TNIK FNBP1 NEDD4L CDK19 VPS8 DGKB URB2 MAP3K4 SLIT1 VPS13B USP33

2.29e-084071221212693553
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

CACNB2 ABI1 ANK3 CUBN ADAM8 PRPF18 SLF2 MYPN SLIT1 MKI67 HACD1 CFAP46

2.83e-084151221216385451
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CACNA1A EVL CACNB2 ABI1 NEDD4L ANK3 LZTS3 MAP4K3 DGKB GEMIN5 PSMD3 ACTN3 PLEKHA6 ARCN1 MAPK8IP3 CKB C12orf50 BSN ATP2B3 TOP1

1.31e-0714311222037142655
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

FNBP1 EVL CACNB2 TRPC4AP NEDD4L ANK3 MID2 KIZ CDK19 ASH1L WDR27 ZSWIM1 MAPK8IP3 ZNF462 IFRD1 ZNF638 NUMB VGLL4 VPS13B

1.10e-0614891221928611215
Pubmed

The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development.

LZTS3 GATA3 MKI67

6.81e-0611122321949185
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1A CACNB2 RYR1 ATP2B3

9.70e-0638122430786075
Pubmed

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer.

ANK3 BUB1 MKI67

1.17e-0513122315931389
Pubmed

Gata3 directly regulates early inner ear expression of Fgf10.

GATA3 FGF10

1.22e-052122223220102
Pubmed

Muscarinic receptor activation increases hERG channel expression through phosphorylation of ubiquitin ligase Nedd4-2.

NEDD4L KCNH2

1.22e-052122224688054
Pubmed

Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling.

CACNB2 BSN

1.22e-052122221092861
Pubmed

The T cell receptor from an influenza-A specific murine CTL clone.

TRBV12-4 TRBV12-3

1.22e-05212222784852
Pubmed

Interaction between superantigen and T-cell receptor Vbeta element determines levels of superantigen-dependent cell-mediated cytotoxicity of CD8(+) T cells in induction and effector phases.

TRBV12-4 TRBV12-3

1.22e-052122219659929
Pubmed

Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores.

GATA3 MKI67

1.22e-052122219946260
Pubmed

Gata-3 and KI-67 expression in correlation with molecular subtypes of breast cancer.

GATA3 MKI67

1.22e-052122234057115
Pubmed

A conserved sequence in the T-cell receptor beta-chain promoter region.

TRBV12-4 TRBV12-3

1.22e-05212223259318
Pubmed

The Relationship of GATA3 and Ki-67 With Histopathological Prognostic Parameters, Locoregional Recurrence and Disease-free Survival in Invasive Ductal Carcinoma of the Breast.

GATA3 MKI67

1.22e-052122232988889
Pubmed

Immunohistochemical study of DNA topoisomerase I, p53, and Ki-67 in uterine carcinosarcomas.

MKI67 TOP1

3.65e-053122217490723
Pubmed

Analysis of the T cell receptor (TcR) regions in the NOD, NON and CTS mouse strains define new TcR V alpha haplotypes and new deletions in the TcR V beta region.

TRBV12-4 TRBV12-3

3.65e-05312221532150
Pubmed

Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10.

CACNB2 HACD1

3.65e-053122219241460
Pubmed

Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.

CACNA1A RYR1

3.65e-053122218313230
Pubmed

The miR-155/GATA3/IL37 axis modulates the production of proinflammatory cytokines upon TNF-α stimulation to affect psoriasis development.

IL37 GATA3

3.65e-053122232472715
Pubmed

Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2.

NEDD4L KCNH2

3.65e-053122222879586
Pubmed

T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.

TRBV12-4 TRBV12-3

3.65e-05312223490968
Pubmed

Regulation of the human ether-a-go-go-related gene (hERG) channel by Rab4 protein through neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2).

NEDD4L KCNH2

3.65e-053122223792956
Pubmed

BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets.

MAML1 MKI67 NUMB

3.92e-0519122323160044
Pubmed

Human transcription factor protein interaction networks.

VAPA MED8 GATA3 MAML1 PSMD3 RFX7 CKB ZNF462 KLF10 MDC1 MKI67 GNL2 ZBTB10 ZNF638 VGLL4 TOP1

4.13e-0514291221635140242
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ANK3 MKI67 ZNF638 NUMB CRYBG3 ATP2B3 VPS13B

4.17e-05263122734702444
Pubmed

Functional proteomics mapping of a human signaling pathway.

KIF18A NEDD4L ANK3 PSG3 VPS8 ASH1L MAST4 KLF10 ASCC3 MERTK

4.67e-055911221015231748
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

VAPA TNIK CACNA1A EVL ABI1 NEDD4L ANK3 LZTS3 PDK2 PSMD3 ARCN1 MAPK8IP3 CRYBG3 BSN

4.82e-0511391221436417873
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIAA0930 PLK2 ABI1 NEDD4L RFX7 RADIL IFRD1 MAST4 SLF2 NUMB FAM53B CRYBG3

5.29e-058611221236931259
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

VAPA DCAF1 KIAA0930 NEDD4L PSMD3 ARCN1 CKB MRM3 SCML2 GNL2 JOSD1 ASCC3 USP33

5.46e-0510051221319615732
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

VAPA TNIK PIGK MAML1 PRPF18 SCML2 MDC1 GNL2 ZNF638 PRR14L USP33

5.71e-057331221134672954
Pubmed

E3 ubiquitin ligase RFWD2 controls lung branching through protein-level regulation of ETV transcription factors.

NEDD4L CUBN FGF10

6.18e-0522122327335464
Pubmed

PEG3 binds to H19-ICR as a transcriptional repressor.

TNIK PDK2 PRPF18

6.18e-0522122327824289
Pubmed

Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin.

ANK3 MKI67

7.29e-054122224821222
Pubmed

Disruption of protein quality control of the human ether-à-go-go related gene K+ channel results in profound long QT syndrome.

KCNH2 RNF207

7.29e-054122234634443
Pubmed

Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).

NEDD4L KCNH2

7.29e-054122226363003
Pubmed

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

TRBV12-4 TRBV12-3

7.29e-05412223456168
Pubmed

Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2.

GATA3 MKI67

7.29e-054122220484821
Pubmed

Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes.

TRBV12-4 TRBV12-3

7.29e-05412223470773
Pubmed

Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1.

NEDD4L KCNH2

7.29e-054122221463633
Pubmed

Germline organization of the murine T cell receptor beta-chain genes.

TRBV12-4 TRBV12-3

1.21e-04512222821625
Pubmed

Harderian Gland Development and Degeneration in the Fgf10-Deficient Heterozygous Mouse.

MKI67 FGF10

1.21e-045122238921483
Pubmed

Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.

CACNA1A CACNB2

1.21e-045122216787652
Pubmed

Bmp7 regulates branching morphogenesis of the lacrimal gland by promoting mesenchymal proliferation and condensation.

MKI67 FGF10

1.21e-045122215280212
Pubmed

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.

SCML2 MDC1 MKI67 TOP1

1.23e-0472122431248990
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TNIK CACNB2 ABI1 NEDD4L ANK3 MAP4K3 PLEKHA6 NUMB

1.25e-04421122836976175
Pubmed

TopBP1 controls BLM protein level to maintain genome stability.

DCAF1 MDC1 ZBTB10

1.44e-0429122324239288
Pubmed

Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons.

GATA3 MKI67

1.81e-046122231619968
Pubmed

Genome-wide association study of bipolar I disorder in the Han Chinese population.

CACNB2 ANK3

1.81e-046122220386566
Pubmed

The serum- and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11.

NEDD4L KCNH2

1.81e-046122223589291
Pubmed

RING finger protein RNF207, a novel regulator of cardiac excitation.

KCNH2 RNF207

1.81e-046122225281747
Pubmed

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice.

CACNB2 ANK3

1.81e-046122220877009
Pubmed

beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.

CACNA1A CACNB2

1.81e-046122210328888
Pubmed

Lhx9 gene expression during early limb development in mice requires the FGF signalling pathway.

MKI67 FGF10

1.81e-046122226220830
Pubmed

Identification of chromosomes associated with dental caries susceptibility using quantitative trait locus analysis in mice.

CACNA1A CACNB2

1.81e-046122214767162
Pubmed

Tagging genes with cassette-exchange sites.

VAPA MAP4K3 GEMIN5 RFX7 ZNF462 MKI67 TOP1

1.88e-04335122715741177
Pubmed

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.

OTUD6A JOSD1 USP33

1.94e-0432122333669244
Pubmed

Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.

GATA3 SLIT1 MKI67

1.94e-0432122327806288
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

GATA3 SCML2 MDC1 MKI67 GNL2 ZNF638 TOP1

2.09e-04341122732971831
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

VAPA DCAF1 KIF18A KIAA0930 TRPC4AP MAK ABI1 ANK3 MAML1 BUB1 OSBPL1A ZNF638 NUMB FAM53B

2.27e-0413211221427173435
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A ABI1 NEDD4L PLEKHA6 MAPK8IP3 RADIL BSN

2.33e-04347122717114649
Pubmed

Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.

NEDD4L NUMB

2.53e-047122227940916
Pubmed

A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury.

GATA3 MKI67

2.53e-047122231405951
Pubmed

The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice.

ASH1L MKI67

2.53e-047122228374742
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

DCAF1 IFRD1 MKI67 GNL2 ZNF638 PRR14L CDKN2AIPNL

3.11e-04364122724778252
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

VAPA TNIK NEDD4L PIGK ACTN3 ARCN1 CKB MRM3 MKI67 GNL2 NUMB ASCC3 CDKN2AIPNL TOP1

3.31e-0413711221436244648
Pubmed

RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis.

NUMB REPS2

3.37e-048122212775724
Pubmed

Expression and function of Nkx6.3 in vertebrate hindbrain.

GATA3 MKI67

3.37e-048122218586225
Pubmed

miR-205 is a critical regulator of lacrimal gland development.

MKI67 FGF10

3.37e-048122228511845
Pubmed

Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.

VAPA OSBPL1A

3.37e-048122229858488
Pubmed

Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.

ACTN3 MYPN

3.37e-048122211309420
Pubmed

FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry.

MKI67 FGF10

3.37e-048122225344367
Pubmed

Development of the mammalian urethra is controlled by Fgfr2-IIIb.

MKI67 FGF10

3.37e-048122215843416
Pubmed

Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells.

GATA3 MKI67

3.37e-048122222801971
Pubmed

Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

URB2 FAM53B VGLL4

4.07e-044112238590280
Pubmed

Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development.

GATA3 MKI67 FGF10

4.07e-0441122330377232
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FNBP1 GEMIN5 PLEKHA6 KLF10 MYPN MKI67 ZNF638 NUMB

4.13e-04503122816964243
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

FNBP1 TRPC4AP PIGK MED8 MAML1 URB2 RYR1 BSN ATP2B3

4.32e-04638122931182584
Pubmed

CTCF deficiency causes expansion of the sensory domain in the mouse cochlea.

GATA3 FGF10

4.32e-049122230929920
Pubmed

Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement.

TRBV12-4 TRBV12-3

4.32e-049122211160223
Pubmed

Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb.

MKI67 FGF10

4.32e-049122211489975
Pubmed

Prox1 regulates Olig2 expression to modulate binary fate decisions in spinal cord neurons.

GATA3 MKI67

4.32e-049122225411508
Pubmed

The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.

DCAF1 TOP1

4.32e-049122233524014
Pubmed

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.

CUBN MMUT

4.32e-049122219744961
Pubmed

The role of Six1 in mammalian auditory system development.

GATA3 FGF10

4.32e-049122212874121
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FNBP1 CACNB2 ANK3 MAP4K3 ASH1L GEMIN5 CUBN SCML2 MYPN ZBTB10 ZNF638 VPS13B

4.43e-0410841221211544199
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DCAF1 VPS8 DGKB TESPA1

4.53e-0410112249872452
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TNIK GEMIN5 ARCN1 CKB SCML2 MKI67 GNL2 ZNF638 NUMB PRR14L TOP1

4.63e-049341221133916271
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

KIAA0930 NEDD4L ZNF638 FAM53B

4.70e-04102122415778465
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

SCML2 MDC1 MKI67 GNL2 ZNF638 TOP1

5.06e-04283122630585729
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GEMIN5 URB2 CKB MDC1 MKI67 GNL2 ZNF638 ASCC3 TOP1

5.10e-04653122922586326
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TNIK FNBP1 LZTS3 VPS13B

5.24e-0410512249628581
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

DCAF1 MID2 URB2 CKB MRM3 ASCC3

5.25e-04285122632838362
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK3 MKI67

5.39e-0410122222159418
Pubmed

Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.

KCNH2 MKI67

5.39e-0410122222855790
Pubmed

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis.

GATA3 MKI67

5.39e-0410122215525534
Pubmed

NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.

DCAF1 NEDD4L

5.39e-0410122233058421
Pubmed

The Gata3 transcription factor is required for the survival of embryonic and adult sympathetic neurons.

GATA3 MKI67

5.39e-0410122220702712
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

VAPA GEMIN5 ARCN1 SCML2 MKI67

5.85e-04191122531177093
CoexpressionGSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_UP

DCAF1 ACP5 MRM3 IFRD1 KLF10 BUB1 ZNF638 FGF10 MERTK CDKN2AIPNL TOP1

2.18e-0920012011M9633
CoexpressionTSUTSUMI_FBXW8_TARGETS

ACTN3 RYR1 MYPN

7.70e-0691203MM888
CoexpressionTSUTSUMI_FBXW8_TARGETS

ACTN3 RYR1 MYPN

7.70e-0691203M2187
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PIGK URB2 KCNH2 BUB1 FAM227A HACD1

1.52e-0613012160f9d3e6297f48ae14d24ac997d8d3a94f337d4d4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PIGK URB2 KCNH2 BUB1 FAM227A HACD1

1.52e-061301216fc68a648161dd314d9ee6612fd039cb12171b8c6
ToppCellNS-moderate-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TNIK MAML1 TESPA1 MAST4 KCNH2 C19orf18

4.36e-06156121617c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 EVL KIAA0930 ADAM8 RYR1 CKB

9.00e-0617712163cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCellfacs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAK WDR27 WDR93 C20orf96 C12orf50 CFAP46

9.90e-061801216cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK CACNA1A NEDD4L GATA3 TESPA1 MAST4

1.16e-051851216e34473eea3a58c041183a4f52137366cd9489495
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK NEDD4L GATA3 TRDC ZNF462 MAST4

1.23e-051871216b426a67b5669019115b58295ce7d304beeb75825
ToppCell10x5'v1-week_14-16-Lymphocytic_T-T_NK-CD4_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EVL ANK3 GATA3 TESPA1 TRBV12-4 TRBV12-3

1.35e-0519012168fdf35c2ad1d325c00c00e4fcf2506341ff14537
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A NEDD4L GATA3 TRDC ZNF462 MAST4

1.35e-051901216600b9674197f743dea1d19d3df0fc993b6e6aa25
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK NEDD4L ANK3 PLEKHA6 CUBN MAST4

1.39e-0519112163c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK NEDD4L ANK3 PLEKHA6 CUBN MAST4

1.39e-0519112161c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

CACNB2 NEDD4L ANK3 MAST4 MYPN HACD1

1.39e-0519112165d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-early_MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TNIK TEX15 TESPA1 CKB MAST4 HACD1

1.39e-0519112163839bf57419d3ec3d4464277bb33301d2b7d701f
ToppCellcontrol-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TNIK MAML1 TESPA1 ZNF462 MAST4 KCNH2

1.39e-051911216afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

TNIK CACNB2 ANK3 MAST4 MYPN HACD1

1.43e-051921216ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

TNIK CACNB2 ANK3 MAST4 MYPN HACD1

1.47e-051931216dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNB2 PLK2 DGKB FGF10 REPS2 RNF207

1.47e-051931216cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellT_cells-Central_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TNIK EVL ANK3 GATA3 TESPA1 MAP3K4

1.47e-051931216725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FNBP1 EVL GATA3 PLEKHA6 NPIPB5 TESPA1

1.47e-0519312169c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK NEDD4L ANK3 PLEKHA6 CUBN MAST4

1.51e-0519412167002937e8903e037332a215d00fbc7c7843b33f2
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

CACNB2 NEDD4L ANK3 MAST4 MYPN HACD1

1.51e-051941216c3535f7cc0076653c72db582047cff053c322397
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TNIK EVL ANK3 GATA3 TESPA1 MAST4

1.56e-0519512164bdedd924564a260841a9153604026b57487c83d
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TNIK ADAM8 TESPA1 MAST4 KCNH2 HACD1

1.56e-051951216f1f48e2e57b2282572959b152aad4bee05143f03
ToppCell10x5'v1-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK TEX15 TESPA1 CKB MAST4 HACD1

1.56e-0519512169b4f217325afb2efb9c65f298ac87649cb1e1af9
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TNIK EVL ANK3 GATA3 TESPA1 MAST4

1.56e-05195121622191d361af136942508f1553ff41a626ed982ad
ToppCellBronchial-NucSeq-Stromal-Schwann-Schwann_Myelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A CUBN C12orf50 SLIT1 ZBTB10 CDKN2AIPNL

1.61e-051961216efeb272bc9e37e60d15d056b7574991c5c7501bc
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TNIK ADAM8 TESPA1 MAST4 KCNH2 HACD1

1.61e-051961216e08f90f7a923c2846cac859519b8dc7c0ac7cd03
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA12 WDR93 BUB1 FAM227A ATP2B3 CFAP46

1.65e-0519712166e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLB1 URB2 RYR1 WDR93 P2RY11 MERTK

1.70e-0519812162b724d2a36843801984d46a969d33149b76c9771
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK TEX15 TESPA1 CKB MAST4 HACD1

1.70e-051981216fcf53d6ac2e442400fa0c07c6de72e00a9143ba2
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

EVL CACNB2 COL6A5 PLEKHA6 TEX15 FGF10

1.80e-05200121664ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EVL ANK3 GATA3 TESPA1 TRBV12-4 TRBV12-3

1.80e-052001216b7ab3f644e6002635771dccaa192a111b4e0ed5b
ToppCell10x5'v1-week_17-19-Lymphocytic_T|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EVL ANK3 GATA3 TESPA1 TRBV12-4 TRBV12-3

1.80e-0520012162e01a35caeff5967a8b873c5122500d068dcf54c
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

EVL CACNB2 COL6A5 PLEKHA6 TEX15 FGF10

1.80e-052001216a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

EVL CACNB2 COL6A5 PLEKHA6 TEX15 FGF10

1.80e-052001216bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A ABCA12 DGKB CUBN SPATA16

3.90e-051391215a1945b07f177cde40e7eea03a19236ce76165857
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Entopeduncular / BrainAtlas - Mouse McCarroll V32

C12orf50 MYPN VASH2 RNF207

4.45e-057212147877184d5c9dd6d96476d71e7504e58c0b4d0f26
ToppCellsevere_influenza-CD4+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

EVL ANK3 TESPA1 ZNF462 MAST4

7.18e-051581215ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EVL KIZ GATA3 BUB1 FAM53B

7.62e-0516012158e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 ABCA12 DGKB COL6A5 FGF10

7.62e-051601215c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 ABCA12 DGKB COL6A5 FGF10

7.62e-05160121525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLB1 NEDD4L CUBN KCNH2 FAM53B

8.31e-05163121556b8668dbf06faa6866ec71f29b92907b73f074d
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-NK_CD56bright|Multiple_Sclerosis / Disease, Lineage and Cell Type

CILP IL37 GATA3 ADAM8 TRDC

8.31e-05163121582c4b25f05bd404fdee9aa90f23efd6dffc04e7b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK CACNB2 GATA3 RADIL ASCC3

9.06e-051661215ceb0a48c0d853448fd45ac31dde046df9a178571
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1A EVL GATA3 ADAM8 TESPA1

9.32e-051671215c2a0fdb35ec48b956be0686534b29164db6638ab
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM8 NEK3 SLIT1 ZBTB10 REPS2

9.32e-051671215528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM8 NEK3 SLIT1 ZBTB10 REPS2

9.32e-051671215a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAK WDR93 SLIT1 FAM227A CFAP46

9.86e-05169121514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellControl-Myeloid-Mast|Control / Disease state, Lineage and Cell class

TNIK TESPA1 ZNF462 MAST4 KCNH2

1.01e-0417012159a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OTUD6A GATA3 ADAM8 RYR1 P2RY11

1.01e-041701215059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

FNBP1 EVL ANK3 GATA3 TESPA1

1.04e-04171121561318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCellControl-Myeloid-Mast|World / Disease state, Lineage and Cell class

TNIK TESPA1 ZNF462 MAST4 KCNH2

1.04e-041711215ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCNH2 MYPN VASH2 ATP2B3 CFAP46

1.10e-0417312157e3897868dd3f6e4974f593c60649a543ffc8693
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLB1 URB2 BUB1 MKI67 CDKN2AIPNL

1.13e-04174121572df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLB1 URB2 BUB1 MKI67 CDKN2AIPNL

1.13e-041741215c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellControl-Lymphoid-Tregs|Lymphoid / Condition, Lineage and Cell class

PDK2 GATA3 TRDC MAST4 HACD1

1.13e-041741215522a6d5d9809271c63b85f62ac6ec52a6e3c355e
ToppCellmoderate-Myeloid-Mast_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TNIK MAML1 TESPA1 MAST4 KCNH2

1.16e-041751215bbd2971bc6d69e507f90a637834d0936c205c590
ToppCellControl-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

TNIK TESPA1 ZNF462 MAST4 KCNH2

1.19e-0417612150c5916d63e1ada09105e46d2429b75129b7329ec
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAK WDR27 WDR93 C20orf96 CFAP46

1.22e-0417712153cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAK WDR27 WDR93 C20orf96 CFAP46

1.22e-04177121512a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EVL GATA3 ADAM8 RADIL P2RY11

1.22e-041771215fcdd71e2a727ae24b726a39216ea02c06df1f593
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLK2 GATA3 URB2 CUBN MAST4

1.22e-04177121516197068260fc062bf8b730a51a199887ea580b9
ToppCellLV|World / Chamber and Cluster_Paper

TNIK CACNB2 VPS8 MAST4 RNF207

1.32e-0418012155ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK EVL ANK3 GATA3 TESPA1

1.32e-041801215f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ANK3 GATA3 TESPA1 MAP3K4

1.32e-041801215d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

NEDD4L ANK3 LGSN MAST4 TOP1

1.36e-041811215c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EVL GATA3 ADAM8 RADIL P2RY11

1.39e-041821215feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

TNIK TESPA1 ZNF462 MAST4 KCNH2

1.39e-04182121568a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCellCF-Lymphoid-T_cell_&_NK_cell|CF / Disease state, Lineage and Cell class

TNIK EVL GATA3 RFX7 TRDC

1.39e-041821215a8dfc59a3974e3433f434676b7c2749d0fcfc8b2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA1A KIF18A GEMIN5 BUB1 MKI67

1.47e-041841215a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA1A KIF18A GEMIN5 BUB1 MKI67

1.47e-041841215081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

CACNA1A KIF18A GEMIN5 BUB1 MKI67

1.47e-04184121545f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNA1A KIF18A GEMIN5 BUB1 MKI67

1.47e-04184121584c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CACNA1A KIF18A GEMIN5 BUB1 MKI67

1.47e-041841215d31d4116d1d196633784863781fa45673607a421
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

CACNA1A KIF18A GEMIN5 BUB1 MKI67

1.47e-041841215c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DGKB CUBN LGSN MAST4 REPS2

1.47e-0418412159434731f651820b05335085582960f08fbf895de
ToppCellcontrol-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TNIK TESPA1 KCNH2 OSBPL1A SERPIND1

1.47e-041841215fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

CACNA1A KIF18A GEMIN5 BUB1 MKI67

1.47e-0418412152fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KIF18A ABCA12 BUB1 MKI67 C19orf18

1.54e-04186121586d145f965c311189e7996390eef491642417c5c
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

TNIK TESPA1 ZNF462 MAST4 KCNH2

1.54e-041861215def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK EVL ANK3 GATA3 TESPA1

1.54e-041861215c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLK2 NEDD4L IFRD1 ZBTB10 JOSD1

1.54e-04186121535f32fc2761435356c8f54b5bb2f026b8c070efe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA0930 DGKB CUBN LGSN MAST4

1.54e-041861215b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EVL ADAM8 TESPA1 CKB ZNF462

1.58e-041871215fae08f34dc4b15352bd4d10bc6c924fe119b5d5e
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EVL ADAM8 TESPA1 CKB ZNF462

1.58e-041871215e6b140b9fb582abf07aa6ea9bc437de3ba0d6de1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ANK3 GATA3 TESPA1 MAP3K4

1.58e-041871215e1d6c1194476cf26969e405b0951796fed519f44
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EVL ACP5 GATA3 MAST4 HACD1

1.58e-0418712159fdfca5b70f585843ef9d810154674a8e561e765
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EVL ACP5 GATA3 MAST4 HACD1

1.58e-041871215a525753a8a908ee1ef0b8f06e68855e4af27bf86
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNIK NEDD4L ANK3 MAST4 TOP1

1.58e-041871215030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCelldroplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCML2 BUB1 MKI67 REPS2 HACD1

1.62e-0418812151a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TNIK EVL GATA3 MAST4 HACD1

1.62e-0418812159db3d3010cb8a1f3ee1cdccaf3cbaac3cf983fc5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TNIK EVL GATA3 MAST4 HACD1

1.62e-04188121572be6fe654f3a5f654d3b9680145bce7ae9b721d
ToppCellCOVID-19_Mild-Lymphoid_T/NK-Treg|COVID-19_Mild / Disease group, lineage and cell class

TNIK EVL GATA3 MAST4 HACD1

1.62e-04188121542553fdc127e5f613ffd5067620a768a40f1a8a1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK EVL ANK3 GATA3 TESPA1

1.66e-0418912159ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK EVL ANK3 GATA3 TESPA1

1.66e-0418912158130102c41b2978a8b83f765ce383f836a464795
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK EVL ANK3 GATA3 TESPA1

1.66e-0418912155a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellICU-SEP-Lymphocyte-T_NK-CD4_TCM|ICU-SEP / Disease, Lineage and Cell Type

EVL ANK3 GATA3 TESPA1 MAST4

1.66e-0418912159ed1cf4bb456780c1d1070de687bcabafd6287a3
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

CACNB2 ANK3 MAPK8IP3 MAST4 MYPN

1.66e-0418912150a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EVL ANK3 GATA3 TESPA1 MAST4

1.70e-04190121555df73c8b696967a925b1772631f6900eff0fa30
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

CACNB2 ANK3 MAPK8IP3 MAST4 MYPN

1.70e-04190121593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
Drug(-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; PC3; HT_HG-U133A

TNIK MID2 CDK19 ASH1L TESPA1 SCML2 MAST4 VASH2 VPS13B

9.77e-0719911897267_DN
Diseasearachidonic acid measurement

CACNA1A FNBP1 CDK19

1.28e-04251163EFO_0006808
Diseasecerebellar ataxia (implicated_via_orthology)

CACNA1A GEMIN5

4.22e-0481162DOID:0050753 (implicated_via_orthology)
Diseasedentate gyrus volume measurement

TNIK MAST4 FAM53B

4.88e-04391163EFO_0010083
Diseasehippocampal CA4 volume

TNIK MAST4 FAM53B

5.66e-04411163EFO_0009396
Diseasegrey matter volume measurement

CUBN RFX7 ASCC3

6.97e-04441163EFO_0005420
DiseaseShortened QT interval

CACNB2 KCNH2

8.23e-04111162C0151879
DiseaseC-reactive protein measurement

CACNB2 ANK3 IL37 MAPK8IP3 RADIL KLF10 SPATA16 JOSD1 NUMB FAM227A MERTK BSN TOP1

9.28e-04120611613EFO_0004458
DiseaseCongenital myopathy (disorder)

RYR1 HACD1

9.86e-04121162C0270960
DiseaseN-acetyl-isoputreanine measurement

ADAM8 KCNH2

1.16e-03131162EFO_0800107
DiseaseT wave morphology measurement

KCNH2 RNF207

1.35e-03141162EFO_0008398
Diseaseasthma, body mass index

PSMD3 ACTN3

1.35e-03141162EFO_0004340, MONDO_0004979
DiseaseHypertrophic Cardiomyopathy

CACNB2 KLF10 MYPN

1.48e-03571163C0007194
DiseaseTremor, Rubral

CACNA1A ARCN1

1.77e-03161162C0750940
DiseaseAtaxia, Appendicular

CACNA1A ARCN1

1.77e-03161162C0750937
DiseaseAtaxia, Motor

CACNA1A ARCN1

1.77e-03161162C0278161
DiseaseAbnormal coordination

CACNA1A ARCN1

1.77e-03161162C0520966
DiseaseAtaxia, Truncal

CACNA1A ARCN1

1.77e-03161162C0427190
DiseaseAtaxia, Sensory

CACNA1A ARCN1

1.77e-03161162C0240991
DiseaseCongenital Fiber Type Disproportion

RYR1 HACD1

2.25e-03181162C0546264
Diseaseacute lymphoblastic leukemia, response to antineoplastic agent

GATA3 DGKB

2.51e-03191162EFO_0000220, GO_0097327
DiseaseJT interval

CACNB2 TRPC4AP IFRD1 KCNH2 RNF207

3.03e-032481165EFO_0007885
Diseaseaspartate aminotransferase measurement

CACNB2 PLB1 NEDD4L CUBN CKB MYPN ZNF638 MERTK HACD1 MMUT

3.04e-0390411610EFO_0004736
DiseaseRetinitis pigmentosa

MAK KIZ MERTK

3.13e-03741163cv:C0035334
DiseaseIGF-1 measurement

NEDD4L KIZ MED8 DGKB MAPK8IP3 ZNF462 SLIT1

3.22e-034881167EFO_0004627
Diseaseendometriosis

CACNA1A WDR27 MAP3K4 BSN VPS13B

3.25e-032521165EFO_0001065
DiseaseParoxysmal atrial fibrillation

DGKB ZNF462 KCNH2 MYPN

3.40e-031561164C0235480
Diseasefamilial atrial fibrillation

DGKB ZNF462 KCNH2 MYPN

3.40e-031561164C3468561
DiseasePersistent atrial fibrillation

DGKB ZNF462 KCNH2 MYPN

3.40e-031561164C2585653
DiseaseAtrial Fibrillation

DGKB ZNF462 KCNH2 MYPN

3.72e-031601164C0004238
Diseaselean body mass

KIZ ZNF462 SLF2 KCNH2 ZNF638 VGLL4

3.92e-033791166EFO_0004995

Protein segments in the cluster

PeptideGeneStartEntry
SKHKFMVQTIFAPPN

VAPA

91

Q9P0L0
HPKVMLKAIPSFLNS

URB2

1381

Q14146
FAISAKPLTRHMPQN

CACNA1A

1536

O00555
KPLTRHMPQNKQSFQ

CACNA1A

1541

O00555
ADTKKANHMFIPPSA

FAM227A

521

F5H4B4
NNPLSKKLSPVHSEM

ASH1L

171

Q9NR48
HRASKANKKPMQLPR

CDK19

111

Q9BWU1
PIQEKSPKQALSSHM

BUB1

656

O43683
KNLPGHSKNTPLAMS

CRYBG3

1506

Q68DQ2
FPRAFKKLLHTMNVP

BLOC1S4

166

Q9NUP1
AMLPSSQRPKGNHTK

ABCA12

741

Q86UK0
KSRKFMRPNAFHSPL

CFAP46

806

Q8IYW2
AASPTNPMKFLRNKA

C19orf18

76

Q8NEA5
KNTSRTHKIIAPANM

ABI1

116

Q8IZP0
APKTTMGRSNPLFHQ

ADAM8

691

P78325
KPESKTSIHNFMATP

ATP2B3

1131

Q16720
NSVTSPHSKEKRMPF

CACNB2

251

Q08289
NHPSRKKVNFLDMSL

LUZP4

16

Q9P127
PAFISKTNNHIMKLT

SERPIND1

256

P05546
HFIMSPPTKSKLKRQ

RADIL

6

Q96JH8
KMNLENRPPRSSKAH

OTUD6A

81

Q7L8S5
SHEQNSLFLMKPKPG

MAML1

551

Q92585
PPVQQANSLHTSKMK

C20orf96

41

Q9NUD7
LPQNPKSSEHTLAKM

DCAF1

711

Q9Y4B6
RALFLMTKSNFQPPK

MAP4K3

221

Q8IVH8
AMPTLSFSHLKRPQQ

P2RY11

161

Q96G91
PKSQRKRPNLFASDM

GNL2

146

Q13823
PSAFKPVVPKNFHSM

LZTS3

161

O60299
RKRSLATMDSPPHQK

MDC1

1811

Q14676
QPKTMQIEKSFDAHP

MAPK8IP3

1071

Q9UPT6
LPHFTKQPESMNVTR

MERTK

196

Q12866
MPFSNSHNALKLRFP

CKB

1

P12277
RKAFQNPSTVTLMKP

KIF18A

711

Q8NI77
LRALAMKFKTTHAPP

KCNH2

751

Q12809
KSQQVFASPSKHPMD

KIAA0930

136

Q6ICG6
LQKAGPKPSSLSMAH

BSN

3476

Q9UPA5
PHKTLYVPNRKVNSM

DCAF4L2

116

Q8NA75
LHTPKKMSQGPTLFS

FAM53B

26

Q14153
MPVHAQKKPSLTESS

FAM205A

1196

Q6ZU69
EAKSPLQSQPHSRMK

EVL

351

Q9UI08
NIKTPAFHPQRMISR

NPIPB5

571

A8MRT5
QRLSPNTMVTPHKKS

JOSD1

61

Q15040
FRKQTPSAGKAMHTP

MKI67

1771

P46013
TGFMKHTPTKLRAPA

ODF3

36

Q96PU9
AHREPKSQKPFRKMQ

KIZ

351

Q2M2Z5
KKHRTSLPSPMFSRN

OSBPL1A

531

Q9BXW6
NPKPATVFSHKNMEL

PIGK

96

Q92643
QMFKRNPSHRPSATT

NEK3

236

P51956
EHFSKFSPSPLSMKQ

PDK2

21

Q15119
KRPPNVKSSNNSMLL

CUBN

3116

O60494
PKNSSFNPAALSRHM

GATA3

386

P23771
PTMNFVHTSPKVKNL

IL37

41

Q9NZH6
KKNKLMSLLTSPHQP

FNBP1

326

Q96RU3
PLSHRFNEFMTSKPK

FNBP1

366

Q96RU3
TFKGRSPMLNHLKKN

COL6A5

86

A8TX70
PHVKKTGMFSIRLPN

HACD1

226

B0YJ81
HRMSSTPVKAVPQKT

CENPJ

611

Q9HC77
TPCTIKITHKNQAPM

DGKB

766

Q9Y6T7
SPKDTFPPNHMSNTK

ANK3

3871

Q12955
VKNMPTKPNGTLSHK

MAK

376

P20794
MPKNKKRNTPHRGSS

IFRD1

1

O00458
NSKIAQAFPSKMHSP

MAST4

1406

O15021
VSNLMAPAPSTVHFK

KLF10

106

Q13118
SSAARHKMTLNPRKQ

KIAA1210

401

Q9ULL0
KTRRKNTSAHFLPMV

FGF10

191

O15520
VQPKMSASFVPDHKA

RYR1

2486

P21817
VSSPHQRASAKMKPI

BVES

321

Q8NE79
KRTSEATKMHAPPIN

ARCN1

256

P48444
SQILTPPQLSSRMKH

LGSN

61

Q5TDP6
APTKSLVSHIPKQMS

PRR14L

1581

Q5THK1
SLPMTHSLQLSKNKR

PSG3

186

Q16557
PSGIKTNIKSASMHP

MED8

251

Q96G25
KQMPNFTHIQTSPSK

PPEF1

151

O14829
PALSQKMSPFKRQLS

NUMB

281

P49757
RPASRSNLKEKMNAP

MAP3K4

106

Q9Y6R4
KMSGSPVQKPTLHRS

RNF207

391

Q6ZRF8
MSFSVHNQKGSKRPL

TEX47

1

Q8TBZ9
LPHTSARTQLPQSMK

TRPC4AP

366

Q8TEL6
KMTYPKTQLQHSLPL

MRM3

196

Q9HC36
PQPKSSHSLNMDKVA

OR5AL1

276

P0C617
NTSKKMSTLAHPPNI

SPATA16

26

Q9BXB7
TPSQVKMSPSYHQSK

VPS8

1331

Q8N3P4
KRKMQAQSPYLPHSG

SLC25A43

226

Q8WUT9
KPASKQDRHMLDSPQ

SLF2

56

Q8IX21
NMPSKSVHSLKPSDI

PLB1

56

Q6P1J6
VKSLPMRAQFKANHP

SERPINB11

356

Q96P15
QTKLRLSHRPAFMPS

ACTN3

356

Q08043
LPQFTTRSELMKKHQ

CDKN2AIPNL

101

Q96HQ2
LPHFKMNSAAPSNKD

CENPBD1P

151

B2RD01
MNKPAFQAIRSHSPA

ASCC3

1541

Q8N3C0
KTAFQISMAKPRPNS

CILP

871

O75339
SSMNDVQPVKKPHFK

C12orf50

271

Q8NA57
NNKMPLSTHRFKREP

C11orf1

106

Q9H5F2
KMSRIFNPHLNKTAN

VGLL4

76

Q14135
GKRSHSMKRNPNAPV

PLEKHA6

46

Q9Y2H5
SRLNRQSSPAMPHKV

TNIK

541

Q9UKE5
QSSPAMPHKVANRIS

TNIK

546

Q9UKE5
TNVKNMAKLSPIPHT

ZNF826P

11

Q6ZT77
IHNMSVKAMRFPPKS

PSMD3

486

O43242
SAATMKPHPTVQKQS

REPS2

591

Q8NFH8
SCKNQRPMFPPIHKS

SPATA31A1

1096

Q5TZJ5
PKSSPHEVKFQMQRK

SCML2

591

Q9UQR0
LTSMQDHSRPPQGKK

GEMIN5

711

Q8TEQ6
AKMPNASFSTLKIQP

TRBV12-3

86

P01733
GNFMDPSKRHQRKVP

ACP5

261

P13686
RMKILKPASAHSPTQ

VASH2

291

Q86V25
DFHLSTREMPQSKPK

TTLL2

496

Q9BWV7
GLRKKAFVHMPTLPN

RFX7

81

Q2KHR2
TQMPDPKTFKQHFES

ZNF706

46

Q9Y5V0
AKMPNASFSTLKIQP

TRBV12-4

86

A0A0B4J2E0
SRKKPVLSPHNSIMF

nan

26

Q8N9G6
MSFPRGSQTQKIKHP

WDR93

1

Q6P2C0
KRKSPGQPMRTHTLT

VPS13B

1526

Q7Z7G8
SQPHTKPSVFVMKNG

TRDC

1

B7Z8K6
MKPKSPHNSGLVNLT

ZNF462

346

Q96JM2
VSKTPVQKFTPSHMF

TESPA1

241

A2RU30
VQHFPLARPKSLMQK

ZBTB10

231

Q96DT7
PAKHLIASMLSKNPE

PLK2

306

Q9NYY3
SAPHVTMFSPKTNIK

WDR27

461

A2RRH5
NHLTPKKVEMQRSLP

TEX15

2381

Q9BXT5
KDSSPPMLLHQVNKT

ZSWIM1

41

Q9BR11
TNSQPFKLDPKMTHK

MID2

531

Q9UJV3
IPVSSFNHMPKLRTF

SLIT1

196

O75093
LMTICQKHFPTDPSK

PRPF18

321

Q99633
NHQRAPPKTFEKSMM

TOP1

631

P11387
FSHADAQKMKRLPTP

ZNF638

396

Q14966
EKIPNKMSAFRNHCP

USP33

26

Q8TEY7
GKSFPSKSQLQMHKR

ZNF81

476

P51508
MFQPKNSKSLLLRAH

MMUT

336

P22033
ARKRLSPDQMKHSPN

MYPN

96

Q86TC9
KFPVHMRSKTSLNPN

NEDD4L

531

Q96PU5