Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA end binding	XRCC5 NHEJ1	3.63e-05	3	70	2	GO:0045027
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 CCDC88C DYNC2H1	1.27e-04	28	70	3	GO:0051959
GeneOntologyMolecularFunction	tumor necrosis factor binding	TRAF2 TMC8	2.52e-04	7	70	2	GO:0043120
GeneOntologyCellularComponent	DNA-dependent protein kinase-DNA ligase 4 complex	XRCC5 NHEJ1	2.17e-04	7	68	2	GO:0005958
GeneOntologyCellularComponent	nonhomologous end joining complex	XRCC5 NHEJ1	3.70e-04	9	68	2	GO:0070419
GeneOntologyCellularComponent	axoneme	DNHD1 RPGRIP1 DYNC2H1 GAS8 CFAP69	5.70e-04	207	68	5	GO:0005930
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DNHD1 RPGRIP1 DST DYNC2H1 GAS8 CFAP69	5.76e-04	317	68	6	GO:0032838
GeneOntologyCellularComponent	ciliary plasm	DNHD1 RPGRIP1 DYNC2H1 GAS8 CFAP69	5.83e-04	208	68	5	GO:0097014
GeneOntologyCellularComponent	lamellipodium	DPYSL3 SWAP70 SYNE2 AMOTL1 DMD	9.16e-04	230	68	5	GO:0030027
GeneOntologyCellularComponent	cytoplasmic region	DNHD1 RPGRIP1 DST DYNC2H1 GAS8 CFAP69	1.12e-03	360	68	6	GO:0099568
GeneOntologyCellularComponent	cell leading edge	DPYSL3 DST SWAP70 SYNE2 AMOTL1 PLCG2 DMD	1.18e-03	500	68	7	GO:0031252
MousePheno	abnormal stomach morphology	THBS1 ANKRD20A4P GARS1 GAS8 ANKRD20A3P ANKRD20A8P ANKRD20A1 TNS3	7.81e-06	248	58	8	MP:0000470
MousePheno	enlarged stomach	ANKRD20A4P ANKRD20A3P ANKRD20A8P ANKRD20A1	9.98e-06	33	58	4	MP:0003883
Domain	DUF4599	SPATA31D4 SPATA31D1 SPATA31D3	9.49e-06	12	67	3	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D1 SPATA31D3	9.49e-06	12	67	3	IPR027970
Domain	Actinin_actin-bd_CS	DST SYNE2 DMD	7.42e-05	23	67	3	IPR001589
Domain	Spectrin	DST SYNE2 DMD	7.42e-05	23	67	3	PF00435
Domain	ACTININ_2	DST SYNE2 DMD	7.42e-05	23	67	3	PS00020
Domain	ACTININ_1	DST SYNE2 DMD	7.42e-05	23	67	3	PS00019
Domain	Spectrin_repeat	DST SYNE2 DMD	1.51e-04	29	67	3	IPR002017
Domain	Spectrin/alpha-actinin	DST SYNE2 DMD	2.03e-04	32	67	3	IPR018159
Domain	SPEC	DST SYNE2 DMD	2.03e-04	32	67	3	SM00150
Domain	Dynein_HC_stalk	DNHD1 DYNC2H1	1.12e-03	14	67	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DYNC2H1	1.12e-03	14	67	2	IPR013602
Domain	DHC_N2	DNHD1 DYNC2H1	1.12e-03	14	67	2	PF08393
Domain	MT	DNHD1 DYNC2H1	1.12e-03	14	67	2	PF12777
Domain	DHC_fam	DNHD1 DYNC2H1	1.29e-03	15	67	2	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DYNC2H1	1.29e-03	15	67	2	IPR004273
Domain	Dynein_heavy	DNHD1 DYNC2H1	1.29e-03	15	67	2	PF03028
Domain	CH	DST SYNE2 DMD	1.64e-03	65	67	3	SM00033
Domain	CH	DST SYNE2 DMD	2.03e-03	70	67	3	PF00307
Domain	-	DST SYNE2 DMD	2.12e-03	71	67	3	1.10.418.10
Domain	CH	DST SYNE2 DMD	2.29e-03	73	67	3	PS50021
Domain	CH-domain	DST SYNE2 DMD	2.48e-03	75	67	3	IPR001715
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A4P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.17e-09	8	72	4	12634303
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	THBS1 DST AMOTL1 GARS1 HUWE1 TTC3 SEC14L5 TNS3	4.46e-07	332	72	8	37433992
Pubmed	Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin.	THBS1 PLCG2 TEK	3.05e-06	14	72	3	33619517
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	SPATA31D4 SPATA31D3 DST ZNF282 TNS3 ZNF292	9.16e-06	233	72	6	37704626
Pubmed	Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.	HUWE1 MAPK9	1.27e-05	3	72	2	22748923
Pubmed	Loss of the HPV-infection resistance EVER2 protein impairs NF-κB signaling pathways in keratinocytes.	TRAF2 TMC8	1.27e-05	3	72	2	24586810
Pubmed	XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.	XRCC5 NHEJ1	1.27e-05	3	72	2	30291363
Pubmed	Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway.	TRAF2 MAPK9	1.27e-05	3	72	2	8985011
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	THBS1 DMD TTC3 ZNF292	1.48e-05	71	72	4	33541421
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	DPYSL3 PNN SWAP70 ANAPC1 AMOTL1 HAUS5 HUWE1 MED23	1.81e-05	549	72	8	38280479
Pubmed	An investigation into the human serum "interactome".	C1QA CP DMD TNS3 ZNF292	2.24e-05	162	72	5	15174051
Pubmed	Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF.	XRCC5 NHEJ1	2.53e-05	4	72	2	21349273
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST DMD	2.53e-05	4	72	2	8954775
Pubmed	X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology.	XRCC5 NHEJ1	2.53e-05	4	72	2	34056803
Pubmed	Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina.	ACO1 CP	2.53e-05	4	72	2	15354085
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ATP5PB RPGRIP1 EME1 DST PNN SYNE2 GARS1 DMD XRCC5 TTC3 CFAP69 ZNF292	3.78e-05	1442	72	12	35575683
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	IVL TRAF2 DYNC2H1 AMOTL1 CHPF ULBP3	3.94e-05	302	72	6	30561431
Pubmed	Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening.	DMD XRCC5	4.21e-05	5	72	2	33979621
Pubmed	Distinct calcium channels regulate responses of primary B lymphocytes to B cell receptor engagement and mechanical stimuli.	TRPM2 PLCG2	4.21e-05	5	72	2	15611229
Pubmed	TANK potentiates tumor necrosis factor receptor-associated factor-mediated c-Jun N-terminal kinase/stress-activated protein kinase activation through the germinal center kinase pathway.	TRAF2 MAPK9	4.21e-05	5	72	2	10490605
Pubmed	Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.	ZNF33A ZNF33B	4.21e-05	5	72	2	8464732
Pubmed	Cooperative assembly of a protein-DNA filament for nonhomologous end joining.	XRCC5 NHEJ1	4.21e-05	5	72	2	23620595
Pubmed	RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair.	XRCC5 NHEJ1	4.21e-05	5	72	2	26833222
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DNHD1 DST DYNC2H1 SYNE2 DMD	4.45e-05	187	72	5	26460568
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ATP5PB EME1 DPYSL3 DST HAUS5 CP HUWE1 MED23	5.65e-05	645	72	8	25281560
Pubmed	Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.	XRCC5 NHEJ1	6.31e-05	6	72	2	34352203
Pubmed	Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53.	XRCC5 NHEJ1	6.31e-05	6	72	2	30579708
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	CCDC88C DST SWAP70 AMOTL1	8.55e-05	111	72	4	22558309
Pubmed	EVER2 protein binds TRADD to promote TNF-α-induced apoptosis.	TRAF2 TMC8	8.82e-05	7	72	2	23429285
Pubmed	TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres.	XRCC5 NHEJ1	8.82e-05	7	72	2	24095731
Pubmed	The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis.	XRCC5 NHEJ1	8.82e-05	7	72	2	31548606
Pubmed	The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression.	HUWE1 FANCA	8.82e-05	7	72	2	33542213
Pubmed	Synthetic lethality between PAXX and XLF in mammalian development.	XRCC5 NHEJ1	8.82e-05	7	72	2	27798842
Pubmed	Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.	XRCC5 NHEJ1	8.82e-05	7	72	2	20383123
Pubmed	XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair.	XRCC5 NHEJ1	1.17e-04	8	72	2	25941166
Pubmed	Biosynthesis of chondroitin sulphate by a Golgi-apparatus-enriched preparation from cultures of mouse mastocytoma cells.	CHPF CHST3	1.17e-04	8	72	2	6781479
Pubmed	Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death.	TRAF2 HUWE1	1.17e-04	8	72	2	26212014
Pubmed	A study of genes that may modulate the expression of hereditary hemochromatosis: transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin.	ACO1 CP	1.17e-04	8	72	2	11783942
Pubmed	Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator.	MED23 XRCC5	1.17e-04	8	72	2	10823961
Pubmed	DNA sequence and analysis of human chromosome 9.	SPATA31D3 ANKRD20A4P ANKRD20A2P ANKRD20A3P CCDC180 ANKRD20A1	1.20e-04	370	72	6	15164053
Pubmed	c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression.	THBS1 TEK	1.51e-04	9	72	2	12368264
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ATP5PB DNHD1 TRAF2 PNN DYNC2H1 ANAPC1 GARS1 HUWE1 MED23 XRCC5 TTC3	1.60e-04	1425	72	11	30948266
Pubmed	The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.	TRAF2 PLCG2 MAPK9 TNS3	1.77e-04	134	72	4	24658140
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	ATP5PB TRAF2 DST ANAPC1 E2F4 XRCC5	1.86e-04	401	72	6	25852190
Pubmed	In silico prediction of physical protein interactions and characterization of interactome orphans.	TRAF2 PLCG2 MAPK9 TNS3	1.87e-04	136	72	4	25402006
Pubmed	NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.	AMOTL1 HUWE1	1.88e-04	10	72	2	33058421
Pubmed	Functional proteomics mapping of a human signaling pathway.	DST ZFYVE9 C1QA PLCG2 HUWE1 TTC3 CHPF	2.24e-04	591	72	7	15231748
Pubmed	FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.	XRCC5 NHEJ1	2.30e-04	11	72	2	26774286
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	DNHD1 THBS1 DYNC2H1 ACO1 HLA-DRA CP HUWE1 DNPH1 CCDC180	2.45e-04	1016	72	9	19056867
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ATP5PB DST DYNC2H1 ACO1 GARS1 CP HUWE1 XRCC5	2.62e-04	807	72	8	30575818
Pubmed	Sensory Nerve Maintains Intervertebral Disc Extracellular Matrix Homeostasis Via CGRP/CHSY1 Axis.	CHPF CHST3	2.75e-04	12	72	2	36047655
Pubmed	MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.	XRCC5 NHEJ1	2.75e-04	12	72	2	30017584
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	DPYSL3 GARS1 XRCC5 TNS3	3.16e-04	156	72	4	32850835
Pubmed	Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis.	GARS1 TEK	3.25e-04	13	72	2	28835631
Pubmed	Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.	IVL DST	3.25e-04	13	72	2	9670011
Pubmed	Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.	ZNF33A ZNF33B	3.78e-04	14	72	2	2014798
Pubmed	Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.	EME1 FANCA	4.36e-04	15	72	2	17289582
Pubmed	Variation within DNA repair pathway genes and risk of multiple sclerosis.	EME1 XRCC5 NHEJ1	4.58e-04	72	72	3	20522537
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DNHD1 RPGRIP1 PNN DYNC2H1 ANAPC1 XRCC5 ZWINT	4.76e-04	670	72	7	22990118
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	IVL PNN SWAP70 ACO1 SYNE2 GARS1 CP HUWE1 XRCC5 TNS3	4.98e-04	1367	72	10	32687490
Pubmed	Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair.	XRCC5 FANCA	4.98e-04	16	72	2	31980815
Pubmed	A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.	THBS1 HLA-DRA	7.06e-04	19	72	2	11707574
Pubmed	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.	EME1 SYNE2 HUWE1	7.44e-04	85	72	3	19596235
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	DST SYNE2 DMD XRCC5	7.60e-04	197	72	4	20811636
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE2 HUWE1 ZNF292	7.96e-04	87	72	3	12465718
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DST GARS1 ANKRD20A3P HUWE1 XRCC5 MAPK9 FANCA	8.27e-04	736	72	7	29676528
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	DST SYNE2 HUWE1	9.36e-04	92	72	3	15840729
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	TRAF2 DST ANAPC1 HAUS5	9.98e-04	212	72	4	33853758
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	TRAF2 HUWE1 TTC3	1.03e-03	95	72	3	29643511
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	DST SYNE2 E2F4	1.12e-03	98	72	3	34943047
Pubmed	Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development.	PLCG2 TEK	1.13e-03	24	72	2	20371769
Pubmed	TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.	IVL DMD XRCC5 CHPF CCDC180	1.19e-03	382	72	5	37249651
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	GARS1 HUWE1 XRCC5 TTC3	1.24e-03	225	72	4	25277244
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	THBS1 TRAF2 DST ACO1 HLA-DRA HUWE1 TTC3 CHPF ZNF292	1.31e-03	1285	72	9	35914814
Pubmed	Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.	CCDC30 SYNE2	1.33e-03	26	72	2	25820252
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	ATP5PB DPYSL3 PNN GARS1 XRCC5	1.41e-03	397	72	5	21319273
Pubmed	Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk.	EME1 XRCC5	1.43e-03	27	72	2	20610542
Pubmed	Molecular Characterization of the Genital Organizer: Gene Expression Profile of the Mouse Urethral Plate Epithelium.	C1QA DMD	1.43e-03	27	72	2	27173853
Pubmed	Unconventional myosin VI in the heart: Involvement in cardiac dysfunction progressing with age.	DMD MAPK9	1.43e-03	27	72	2	37169038
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 DST PNN DMD	1.44e-03	234	72	4	36243803
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DPYSL3 ZFYVE9 SYNE2 HUWE1 DMD MAPK9 TNS3 SHKBP1	1.45e-03	1049	72	8	27880917
Pubmed	Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.	THBS1 TEK	1.77e-03	30	72	2	22171010
Pubmed	Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.	DYNC2H1 ANAPC1	1.77e-03	30	72	2	27568566
Pubmed	Analysis of the Tropism of SARS-CoV-2 Based on the Host Interactome of the Spike Protein.	THBS1 C1QA	1.89e-03	31	72	2	37939376
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	THBS1 ASGR2 C1QA CP	2.02e-03	257	72	4	16335952
Interaction	ANKRD20A4P interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	8.32e-07	6	71	3	int:ANKRD20A4P
Interaction	DHFR interactions	THBS1 TRAF2 HAUS5 E2F4 HUWE1 SHKBP1 FANCA	1.07e-06	152	71	7	int:DHFR
Interaction	ANKRD20A2P interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	1.45e-06	7	71	3	int:ANKRD20A2P
Interaction	ANKRD20A1 interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	6.78e-06	11	71	3	int:ANKRD20A1
Cytoband	9q21.32	SPATA31D4 SPATA31D1 SPATA31D3	3.52e-06	19	72	3	9q21.32
Cytoband	Ensembl 112 genes in cytogenetic band chr9q21	SPATA31D4 SPATA31D1 SPATA31D3 ANKRD20A3P ANKRD20A1	1.61e-05	199	72	5	chr9q21
Cytoband	2q35	XRCC5 NHEJ1 CHPF	2.68e-04	79	72	3	2q35
Cytoband	9p12	ANKRD20A2P ANKRD20A3P	9.58e-04	29	72	2	9p12
Cytoband	Ensembl 112 genes in cytogenetic band chr2q35	XRCC5 NHEJ1 CHPF	1.12e-03	129	72	3	chr2q35
Cytoband	6p12.1	BEND6 DST	1.24e-03	33	72	2	6p12.1
Cytoband	16q24.3	GAS8 FANCA	3.06e-03	52	72	2	16q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr11q21	AMOTL1 MAML2	4.45e-03	63	72	2	chr11q21
Coexpression	HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN	THBS1 DST DMD TTC3 TNS3 ZWINT	3.49e-07	102	71	6	M2124
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPGRIP1 EME1 SWAP70 SYNE2 TMC8 PLCG2 FANCA	6.42e-09	156	72	7	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC30 DYNC2H1 CROCC2 SYNE2 DMD CCDC180 CFAP69	3.21e-08	197	72	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	DST ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	5.38e-07	184	72	6	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HLA-DRA TMC8 C1QA MAML2 PLCG2 TNS3	6.30e-07	189	72	6	389ccb68acb82893709f256315111470cf4beed3
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HLA-DRA TMC8 C1QA MAML2 PLCG2 TNS3	6.30e-07	189	72	6	58465b9407fbce91cca8f199950d6e0054c38fbc
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HLA-DRA TMC8 C1QA MAML2 PLCG2 TNS3	6.30e-07	189	72	6	7ac78441a15a82218deaafd47accff2ea5c8de20
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	6.50e-07	190	72	6	0eef5a8bd88ef8a25a67d9dd522d9472fa4b3d2f
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|COPD / Disease state, Lineage and Cell class	THBS1 DST ACO1 HLA-DRA C1QA TNS3	6.50e-07	190	72	6	006e31606d637033bc81333816ee332773d36b08
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	6.50e-07	190	72	6	2724e8f375d8d9f5f2a77444e0491af264babac5
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HLA-DRA TMC8 C1QA MAML2 PLCG2 TNS3	6.50e-07	190	72	6	d4f954e0748898df69e1710df558564db703dd61
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	6.50e-07	190	72	6	11fbd4e9f02750354b3aadf30edc991f8d4f8f41
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	6.50e-07	190	72	6	148d43dd72e2e22b2cd68e17fedae6bd98b32aee
ToppCell	Severe_COVID-19-Myeloid-TRAM1\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	6.70e-07	191	72	6	bd641aab36276dd952a7265ee79ba455b38d8e6b
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC30 DYNC2H1 CROCC2 PLCG2 CCDC180 CFAP69	7.34e-07	194	72	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	8.02e-07	197	72	6	d8ef5cb88dd66e112cb94217b9ad5cd70164f1d0
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	8.02e-07	197	72	6	33f2fe101ae5744eea3915add37e60aa398bb97f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	8.02e-07	197	72	6	5e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCell	Severe_COVID-19-Myeloid-TRAM2\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	8.02e-07	197	72	6	8a126cfe1529f3d75a806aa492743314a8a43ef9
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	THBS1 DST ACO1 HLA-DRA AMOTL1 C1QA	8.02e-07	197	72	6	9262785807faeb32417fad7ef202405053e453e2
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	CCDC30 DYNC2H1 GAS8 CCDC180 CFAP69	7.59e-06	167	72	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC88C CCDC30 DYNC2H1 CROCC2 CFAP69	8.04e-06	169	72	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 DST C1QA CP HTRA4	8.76e-06	172	72	5	7295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	DPYSL3 ANKRD20A4P CP ANKRD20A2P ANKRD20A3P	9.27e-06	174	72	5	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	PCW_05-06-Immune_Lymphocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HLA-DRA TRPM2 TMC8 C1QA PLCG2	1.12e-05	181	72	5	bd99c5849bb4979c891898312cb9f602c6831b23
ToppCell	PCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HLA-DRA TRPM2 TMC8 C1QA PLCG2	1.18e-05	183	72	5	ffa7f2b2929ea4bd53f3f1ae23bd27f8bb4aac47
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.21e-05	184	72	5	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BEND6 DST ANKRD20A3P DMD ANKRD20A1	1.21e-05	184	72	5	667846c422cfa27e949a24844a305df859cb6760
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	THBS1 DST ACO1 HLA-DRA C1QA	1.21e-05	184	72	5	7fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCell	PCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HLA-DRA TRPM2 TMC8 C1QA PLCG2	1.25e-05	185	72	5	5ec2c3ae5c477645241e8eaf19d222562e1f7ed6
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.28e-05	186	72	5	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC1\|Liver / Manually curated celltypes from each tissue	BEND6 DST HLA-DRA ANKRD20A2P DMD	1.28e-05	186	72	5	e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.28e-05	186	72	5	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HLA-DRA TMC8 C1QA MAML2 PLCG2	1.31e-05	187	72	5	5ce7cf02990465b6f793205e4be07e8337b3570a
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ASGR2 HLA-DRA TRPM2 TMC8 C1QA	1.31e-05	187	72	5	23be50d81f4404a609dea821e1a66d221c0e0615
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.35e-05	188	72	5	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	IPF-Myeloid-cDC1\|IPF / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.35e-05	188	72	5	2331a2bae1383820d598e93aa86c75b101069bac
ToppCell	NS-control-d_0-4-Myeloid-Resident_Macrophage\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPGRIP1 ASGR2 HLA-DRA TRPM2 C1QA	1.42e-05	190	72	5	5215d2a4ac0475c621f6e6c477916149e2f73d64
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	THBS1 DST ACO1 AMOTL1 C1QA	1.45e-05	191	72	5	2b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	THBS1 DST ACO1 AMOTL1 C1QA	1.45e-05	191	72	5	02e1ae144da7274171e055356d10e8d175c5347f
ToppCell	Severe_COVID-19-Myeloid-TRAM3\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	THBS1 DST ACO1 AMOTL1 C1QA	1.45e-05	191	72	5	05867b96199a46a415848409130697c810d18937
ToppCell	BAL-Severe-Myeloid-TRAM\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	THBS1 DST ACO1 AMOTL1 C1QA	1.45e-05	191	72	5	4c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCell	BAL-Severe-Myeloid-TRAM\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 DST ACO1 AMOTL1 C1QA	1.45e-05	191	72	5	de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.45e-05	191	72	5	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.49e-05	192	72	5	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 DST ACO1 AMOTL1 C1QA	1.49e-05	192	72	5	34505a13b8a47c9286c560122fa7861b9c331a08
ToppCell	COVID-19-Myeloid-TRAM1\|COVID-19 / Condition, Lineage and Cell class	THBS1 DST ACO1 AMOTL1 C1QA	1.49e-05	192	72	5	52b8578699325b0d35a2d3ba36772096130ccc0c
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 DST ACO1 AMOTL1 C1QA	1.49e-05	192	72	5	57c1410ebf90c230993e065eb78385daa3360960
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	THBS1 TRPM2 C1QA ZSWIM6 TNS3	1.49e-05	192	72	5	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	THBS1 TRPM2 C1QA ZSWIM6 TNS3	1.53e-05	193	72	5	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CCDC30 DYNC2H1 CROCC2 DMD CFAP69	1.53e-05	193	72	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ASGR2 HLA-DRA TRPM2 TMC8 C1QA	1.57e-05	194	72	5	fad22d5cf62016cad979e6943e357106d8d2a4b4
ToppCell	CTRL-Myeloid-Alveolar_Macrophage\|CTRL / Disease state, Lineage and Cell class	DST ACO1 HLA-DRA C1QA TNS3	1.57e-05	194	72	5	be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCell	LA-08._Macrophage\|LA / Chamber and Cluster_Paper	THBS1 TRPM2 C1QA ZSWIM6 TNS3	1.61e-05	195	72	5	5e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCell	CTRL\|World / Disease state, Lineage and Cell class	DST ACO1 HLA-DRA C1QA TNS3	1.61e-05	195	72	5	cad77cdc6e0aa0875eff5ecd3805a6cf056d729d
ToppCell	PCW_05-06-Hematologic_Myeloid\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ASGR2 HLA-DRA TRPM2 TMC8 C1QA	1.65e-05	196	72	5	b2aee2f67da373a10b0c25e7797e30e3811543a8
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ZSWIM6 TEK	1.69e-05	197	72	5	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PNN SYNE2 PLCG2 MED23 ZNF292	1.69e-05	197	72	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ASGR2 HLA-DRA TRPM2 TMC8 C1QA	1.73e-05	198	72	5	1d242fbe4ae3628103f6b6f910a7641bb1b75266
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BEND6 ANKRD20A4P HLA-DRA ANKRD20A2P ANKRD20A3P	1.73e-05	198	72	5	fa5c15a656d4132950092919600e270f1fd79abf
ToppCell	LPS_IL1RA-Hematopoietic_Lymphocytic-B_cells-B-cells\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.77e-05	199	72	5	0eb8c72edcd34fe0f7ab9438c9c872d63576ef3a
ToppCell	LPS_IL1RA-Hematopoietic_Lymphocytic-B_cells\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.77e-05	199	72	5	2cdc8ae6357723b9e7c0c66be656e6f748a6aa2d
ToppCell	Control_saline-Hematopoietic_Lymphocytic-B_cells\|Control_saline / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.77e-05	199	72	5	a984b83d6e143c1e497726da09d8e1acf1f59a74
ToppCell	Control_saline-Hematopoietic_Lymphocytic-B_cells-B-cells\|Control_saline / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.77e-05	199	72	5	8913a2f255f42a684221fa0c812e254aa43d8704
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THBS1 DST ACO1 HLA-DRA C1QA	1.77e-05	199	72	5	8e9862907b15809d083216e7d6a0f435015e5d15
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Lymphocytic-B_cells\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.81e-05	200	72	5	d124acbe5d46220850fe485ed78f032daddca5b1
ToppCell	LPS_anti-TNF-Hematopoietic_Lymphocytic-B_cells\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.81e-05	200	72	5	2fb3cf5c7a03c3874390a111bba15203599d4859
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Lymphocytic-B_cells-B-cells\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.81e-05	200	72	5	c07e37db9d50b91378d9c8355168745560cdbd25
ToppCell	LPS_anti-TNF-Hematopoietic_Lymphocytic-B_cells-B-cells\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SWAP70 HLA-DRA TMC8 PLCG2 DNPH1	1.81e-05	200	72	5	4c8007a158f0f6b6fa259b25d2387b648bb2fc0d
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	DPYSL3 DST SYNE2 TTC3 ZNF292	1.81e-05	200	72	5	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	(51)_cDC1\|World / shred on Cell_type and subtype	BEND6 DST ASGR2 ANKRD20A3P TEK	1.99e-05	204	72	5	a8cf4180c406674b7541917d1fc6127686ba5f8a
ToppCell	Club_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	IVL CP ANKRD20A2P ANKRD20A1	7.41e-05	138	72	4	133015953fc660d00339f47b415da5e9872313a2
ToppCell	control-Myeloid-CD14_Monocytes_3\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	THBS1 TRPM2 MAP10 CFAP69	7.41e-05	138	72	4	683cae06f710061d7d74c2f75eb511a2af55bacf
ToppCell	normal_Lung-Myeloid_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	BEND6 HLA-DRA TAF1A C1QA	1.05e-04	151	72	4	23b6cf9a36ad0e937f69c75921bddd305a9a526c
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IVL BEND6 TRPM2 ALS2CL	1.08e-04	152	72	4	b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HLA-DRA TMC8 ANKRD20A3P PLCG2	1.16e-04	155	72	4	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	ASGR2 HAUS5 CCDC180 ZWINT	1.19e-04	156	72	4	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	metastatic_Brain-Myeloid_cells-Undetermined\|Myeloid_cells / Location, Cell class and cell subclass	HLA-DRA GAS8 C1QA PLCG2	1.22e-04	157	72	4	6ce7f2ea613e7f8e771860e8c0512274e4f54369
ToppCell	severe_COVID-19-cDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	BEND6 DST DMD ANKRD20A1	1.22e-04	157	72	4	ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-cDC1\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DRA PLCG2 HTRA4 ANKRD20A1	1.25e-04	158	72	4	78a8a498a9c84ed65e0eefaac781d5247c5b477a
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-DC1\|bone_marrow / Manually curated celltypes from each tissue	BEND6 DST HLA-DRA DMD	1.34e-04	161	72	4	2f068ee643de2f647c289779a6624265ab9a749b
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SWAP70 HLA-DRA SYNE2 FANCA	1.38e-04	162	72	4	3e15b3e97a2ade86d0cb0ab15fccb9a2e2e27dd4
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SWAP70 HLA-DRA DMD NHEJ1	1.48e-04	165	72	4	8003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DRA HAUS5 ANKRD20A3P ANKRD20A8P	1.51e-04	166	72	4	da10d0be6b616199d49dd922591c2901f9681583
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST C1QA CP HTRA4	1.51e-04	166	72	4	b3d9b61847c6c96b8cb28b8a6aeda52f43c706ab
ToppCell	droplet-Thymus-nan-3m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SWAP70 TRPM2 PLCG2 CHST3	1.51e-04	166	72	4	c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 SWAP70 ANKRD20A2P TEK	1.62e-04	169	72	4	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC30 DYNC2H1 CROCC2 CFAP69	1.62e-04	169	72	4	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ANKRD20A4P C1QA ANKRD20A2P ANKRD20A1	1.66e-04	170	72	4	81341bf4fe090af70b2091b6b2579ed08d76e22d
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACO1 HLA-DRA C1QA TNS3	1.73e-04	172	72	4	c8ea80042faf923b08ff03d73100533d521d73ef
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC1\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ASGR2 HLA-DRA ANKRD20A3P ANKRD20A1	1.77e-04	173	72	4	d13ae4046a25ee0fb492ddedf44583a879a432e9
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C ZFYVE9 SHKBP1 FANCA	1.77e-04	173	72	4	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C ZFYVE9 SHKBP1 FANCA	1.77e-04	173	72	4	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	LPS-antiTNF-Lymphocytic_B\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SWAP70 TMC8 PLCG2 DNPH1	1.81e-04	174	72	4	cc493654ea3517bc6a145c7f787f304929636f86
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SWAP70 TMC8 PLCG2 DNPH1	1.81e-04	174	72	4	9eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SWAP70 TMC8 PLCG2 DNPH1	1.81e-04	174	72	4	b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRAF2 DST C1QA NHEJ1	1.85e-04	175	72	4	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 TEK ALS2CL CHST3	1.89e-04	176	72	4	a3f27b5d7edf2d396c085efbe35305cfa0afa565
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-GC_B_(II)\|lymph-node_spleen / Manually curated celltypes from each tissue	SWAP70 HLA-DRA SYNE2 DMD	1.89e-04	176	72	4	5788dd5b23ebb52f19d3b5bdbcfe25dee349cf77
ToppCell	Club_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	IVL SYNE2 CP CHST3	1.89e-04	176	72	4	88c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	DST CROCC2 C1QA TEK	2.06e-04	180	72	4	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
Disease	brain edema (implicated_via_orthology)	CP DMD	6.91e-05	6	64	2	DOID:4724 (implicated_via_orthology)
Disease	non-melanoma skin carcinoma	AMOTL1 GAS8 ZSWIM6 ULBP3 FANCA	2.78e-04	265	64	5	EFO_0009260
Disease	smoking status measurement, ulcerative colitis	HLA-DRA XRCC5	3.56e-04	13	64	2	EFO_0000729, EFO_0006527
Disease	heart disease (biomarker_via_orthology)	THBS1 CP	6.17e-04	17	64	2	DOID:114 (biomarker_via_orthology)
Disease	mosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement	IVL HLA-DRA DMD IQCM CHST3	7.34e-04	328	64	5	EFO_0008377, EFO_0008378
Disease	functional brain measurement	THBS1 ACO1 IL17RD	7.63e-04	82	64	3	EFO_0007849
Disease	Parkinson Disease	HLA-DRA TRPM2 CP	8.47e-04	85	64	3	C0030567
Disease	lumbar disc degeneration	DYNC2H1 CHST3	1.69e-03	28	64	2	EFO_0004994
Disease	Ischemia	CP MAPK9	1.69e-03	28	64	2	C0022116

Protein segments in the cluster

Peptide	Gene	Start	Entry
NAWLVQQLDDVHQKE	ANKRD20A1	741	Q5TYW2
ENILHWNVTQHKNIE	ACO1	61	P21399
QQLHKSSQQLWEVTE	ALS2CL	51	Q60I27
ELAQEEVKQHAQELW	ALS2CL	711	Q60I27
NAWLVQQLDDVHQKE	ANKRD20A8P	741	Q5CZ79
VLQLQQGDQVWVEKD	C1QA	206	P02745
IHEQDLEWLQQADVV	DNPH1	76	O43598
QLENAHLVVINSWEE	ASGR2	206	P07307
HLVVINSWEEQKFIV	ASGR2	211	P07307
NAWLVQQLDDVHQKE	ANKRD20A4P	741	Q4UJ75
ITHWNDSVKQEVQNL	DPYSL3	141	Q14195
EAHIWQEEEEVVQAN	AMOTL1	731	Q8IY63
QNVDHITKWIIQADT	DMD	1686	P11532
VWQNENERIHAQETI	DNHD1	1141	Q96M86
VQLWEAHQSELLVQE	CCDC180	526	Q9P1Z9
INWVEKHVVQSISTQ	ATP5PB	216	P24539
EHQTDEKQFQIEKWQ	BEND6	166	Q5SZJ8
TQKQVDDTWDLVHQD	IQCM	396	A0A1B0GVH7
NAWLVQQLDDVHQKE	ANKRD20A2P	741	Q5SQ80
LQEVTIHEKQKESWQ	ANAPC1	61	Q9H1A4
WEKELHHLQEQNVSN	CP	751	P00450
QGTDHIDQWNKVIEQ	MAPK9	226	P45984
EWVIQKIHESQFIIV	IL17RD	406	Q8NFM7
STHWTEQKENQIDQN	MAP10	801	Q9P2G4
QLVERWQNVHVQIDN	DST	1266	Q03001
EVTHNQENVFDLQWL	CCDC88C	161	Q9P219
QKVELAQLQEEWNEH	PNN	211	Q9H307
AQLQEEWNEHNAKII	PNN	216	Q9H307
LSQESHEQCIQWIVK	MED23	51	Q9ULK4
IHEQQEHWAQDLNKV	PLCG2	251	P16885
ILHWRQLVEETQEQV	HAUS5	386	O94927
LKQVVNQVWEAADVL	HUWE1	1481	Q7Z6Z7
SWQEVSHAQQLKQIA	MAML2	426	Q8IZL2
KQLNQIQVHTTEDWA	DYNC2H1	1611	Q8NCM8
NAWLVQQLDDVHQKE	ANKRD20A3P	741	Q5VUR7
NAHVVRNQQWIEVVL	HTRA4	216	P83105
EQELDQHKVWVQQSI	E2F4	111	Q16254
QHKVWVQQSIRNVTE	E2F4	116	Q16254
SQEWTHQQQVKVLEE	CROCC2	1606	H7BZ55
QEVLETQEVHWQRVL	FANCA	376	O15360
QVIEQEQLIHSNKWT	CCDC30	571	Q5VVM6
QESWAIKEEHVIIQA	HLA-DRA	21	P01903
QLHTEAQAQIVQSWK	EME1	416	Q96AY2
QKIIDWSAAQHEELQ	CFAP69	406	A5D8W1
EHVVFVQTNILNWKE	SEC14L5	76	O43304
HWSNELIAEQLQQQV	RPGRIP1	396	Q96KN7
KQLEHGWEQVEQQIQ	SYNE2	2601	Q8WXH0
IQEALLKHQWQQAAE	TAF1A	61	Q15573
IIQTWRQHFIQEEQI	GARS1	161	P41250
VWNAVTKHWQVQEVQ	SHKBP1	311	Q8TBC3
SEINHLEWNVLQKVQ	SPATA31D4	616	Q6ZUB0
LLVSDLQQVWHEQVD	NHEJ1	36	Q9H9Q4
ELQQQHWEQHEEYQK	IVL	86	P07476
LLPVEHQQQKQEVQW	IVL	566	P07476
QESWLNSNLQHVVVI	TNS3	91	Q68CZ2
EIQELQWEIQNTSHL	CHPF	351	Q8IZ52
QVEDWIQKNTQAAHD	CHST3	396	Q7LGC8
TVEGEKQQEHEVQWL	TRAF2	226	Q12933
HGQQWCEVQSQVDQK	ULBP3	46	Q9BZM4
SEINHLEWNVLQKVQ	SPATA31D3	616	P0C874
WQLQQEKHLQHLAEV	ZWINT	156	O95229
NWVVRHQGKELVQTV	THBS1	976	P07996
QLVWQVQEKWHLVED	TMC8	631	Q8IU68
QENQSKHLWEVVFIN	ZNF33B	96	Q06732
EEQVAQTAQALHWIV	TRPM2	1181	O94759
INHLEWNVLQKVQES	SPATA31D1	621	Q6ZQQ2
WEQFQTLVQVAHEKL	ZNF292	126	O60281
IQVSWNIIHQEVNTE	TTC3	1466	P53804
AWQHIQVTNEIVTLN	TEK	491	Q02763
EQEVVEITEWHNEIN	MYH16	866	Q9H6N6
ENQSKHLWEVVFINN	ZNF33A	96	Q06730
WHLDEEQVQEQVKLF	ZSWIM6	361	Q9HCJ5
KWHLEQQQAIQTTEA	SWAP70	466	Q9UH65
QEHIHIQWVDDDKNV	ZFYVE9	1261	O95405
KQEEHQCVWDQQDLA	ZNF282	331	Q9UDV7
VEIKQLNHFWEIVVQ	XRCC5	666	P13010
WEHEVLEQRFTKVQQ	GAS8	326	O95995