Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	intracellular glucose homeostasis	ANG TRPA1 ALMS1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	4.65e-07	218	66	8	GO:0001678
GeneOntologyBiologicalProcess	cellular response to glucose stimulus	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	3.05e-06	196	66	7	GO:0071333
GeneOntologyBiologicalProcess	cellular response to hexose stimulus	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	3.37e-06	199	66	7	GO:0071331
GeneOntologyBiologicalProcess	cellular response to monosaccharide stimulus	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	3.60e-06	201	66	7	GO:0071326
GeneOntologyBiologicalProcess	cellular response to carbohydrate stimulus	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	5.61e-06	215	66	7	GO:0071322
GeneOntologyBiologicalProcess	glucose homeostasis	ANG TRPA1 ALMS1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	1.20e-05	338	66	8	GO:0042593
GeneOntologyBiologicalProcess	carbohydrate homeostasis	ANG TRPA1 ALMS1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	1.23e-05	339	66	8	GO:0033500
GeneOntologyBiologicalProcess	response to glucose	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	1.93e-05	260	66	7	GO:0009749
GeneOntologyBiologicalProcess	response to hexose	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	2.18e-05	265	66	7	GO:0009746
GeneOntologyBiologicalProcess	response to monosaccharide	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	2.57e-05	272	66	7	GO:0034284
GeneOntologyBiologicalProcess	response to carbohydrate	ANG TRPA1 PIK3CA CCDC186 LRP5 HMGCR SIN3A	4.90e-05	301	66	7	GO:0009743
GeneOntologyBiologicalProcess	cellular homeostasis	NPTN ANG TRPA1 ALMS1 PIK3CA CCDC186 RNF135 LRP5 FTH1P19 HMGCR SIN3A	2.59e-04	981	66	11	GO:0019725
GeneOntologyBiologicalProcess	insulin secretion involved in cellular response to glucose stimulus	TRPA1 CCDC186 LRP5 HMGCR	3.21e-04	102	66	4	GO:0035773
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	NPTN ANG TRPA1 ALMS1 PIK3CA CCDC186 LRP5 FTH1P19 HMGCR SIN3A	4.04e-04	866	66	10	GO:0055082
GeneOntologyBiologicalProcess	cellular response to hydroperoxide	DDIAS SIN3A	4.46e-04	10	66	2	GO:0071447
GeneOntologyBiologicalProcess	negative regulation of fibroblast apoptotic process	DDIAS PIK3CA	4.46e-04	10	66	2	GO:2000270
GeneOntologyBiologicalProcess	cytokinesis	DSTN SEPTIN5 SEPTIN4 TEX14 BIRC6	4.94e-04	204	66	5	GO:0000910
GeneOntologyBiologicalProcess	mitotic spindle assembly checkpoint signaling	BUB1B ATM TEX14	5.84e-04	51	66	3	GO:0007094
GeneOntologyBiologicalProcess	spindle assembly checkpoint signaling	BUB1B ATM TEX14	5.84e-04	51	66	3	GO:0071173
GeneOntologyBiologicalProcess	developmental growth	ANG PELO ALMS1 PIK3CA KCNJ8 SIN3A ATM SEMA3G ZMIZ1 TP73	6.00e-04	911	66	10	GO:0048589
GeneOntologyBiologicalProcess	negative regulation of mitotic metaphase/anaphase transition	BUB1B ATM TEX14	6.54e-04	53	66	3	GO:0045841
GeneOntologyBiologicalProcess	negative regulation of mitotic sister chromatid segregation	BUB1B ATM TEX14	6.54e-04	53	66	3	GO:0033048
GeneOntologyBiologicalProcess	negative regulation of sister chromatid segregation	BUB1B ATM TEX14	6.54e-04	53	66	3	GO:0033046
GeneOntologyBiologicalProcess	negative regulation of mitotic sister chromatid separation	BUB1B ATM TEX14	6.54e-04	53	66	3	GO:2000816
GeneOntologyBiologicalProcess	mitotic spindle checkpoint signaling	BUB1B ATM TEX14	6.54e-04	53	66	3	GO:0071174
Domain	DGCR6	DGCR6 DGCR6L	1.19e-05	2	65	2	PF07324
Domain	Gonadal	DGCR6 DGCR6L	1.19e-05	2	65	2	IPR010849
Domain	Septin	SEPTIN5 SEPTIN4	9.08e-04	13	65	2	PF00735
Domain	G_SEPTIN_dom	SEPTIN5 SEPTIN4	9.08e-04	13	65	2	IPR030379
Domain	G_SEPTIN	SEPTIN5 SEPTIN4	9.08e-04	13	65	2	PS51719
Domain	Septin	SEPTIN5 SEPTIN4	1.06e-03	14	65	2	IPR016491
Domain	Ank	CLIP3 TRPA1 ASB10 ANKIB1 TEX14	1.18e-03	228	65	5	PF00023
Domain	PI3/4_kinase_CS	PIK3CA ATM	1.22e-03	15	65	2	IPR018936
Domain	C2	RPGRIP1L PIK3CA UNC13C RGS3	1.33e-03	137	65	4	SM00239
Domain	-	PIK3CA ATM	1.39e-03	16	65	2	1.10.1070.11
Domain	PI3Kc	PIK3CA ATM	1.39e-03	16	65	2	SM00146
Domain	C2	RPGRIP1L PIK3CA UNC13C RGS3	1.51e-03	142	65	4	PS50004
Domain	-	CLIP3 TRPA1 ASB10 ANKIB1 TEX14	1.71e-03	248	65	5	1.25.40.20
Domain	PI3/4_kinase_cat_dom	PIK3CA ATM	1.76e-03	18	65	2	IPR000403
Domain	PI3_PI4_kinase	PIK3CA ATM	1.76e-03	18	65	2	PF00454
Domain	PI3_4_KINASE_3	PIK3CA ATM	1.76e-03	18	65	2	PS50290
Domain	PI3_4_KINASE_1	PIK3CA ATM	1.76e-03	18	65	2	PS00915
Domain	PI3_4_KINASE_2	PIK3CA ATM	1.76e-03	18	65	2	PS00916
Domain	-	RPGRIP1L PIK3CA UNC13C RGS3	1.76e-03	148	65	4	2.60.40.150
Domain	ANK	CLIP3 TRPA1 ASB10 ANKIB1 TEX14	1.80e-03	251	65	5	SM00248
Domain	ANK_REPEAT	CLIP3 TRPA1 ASB10 ANKIB1 TEX14	1.87e-03	253	65	5	PS50088
Domain	Ankyrin_rpt-contain_dom	CLIP3 TRPA1 ASB10 ANKIB1 TEX14	1.90e-03	254	65	5	IPR020683
Domain	ANK_REP_REGION	CLIP3 TRPA1 ASB10 ANKIB1 TEX14	1.90e-03	254	65	5	PS50297
Domain	Ankyrin_rpt	CLIP3 TRPA1 ASB10 ANKIB1 TEX14	2.18e-03	262	65	5	IPR002110
Domain	C2_dom	RPGRIP1L PIK3CA UNC13C RGS3	2.56e-03	164	65	4	IPR000008
Domain	Kinase-like_dom	TYK2 PIK3CA BUB1B CHD9 ATM TEX14 RPS6KC1	2.71e-03	542	65	7	IPR011009
Domain	Ank_2	CLIP3 TRPA1 ASB10 TEX14	6.68e-03	215	65	4	PF12796
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RLF ALMS1 POLH BUB1B TNRC6B ZMIZ1 BIRC6 ZBTB1	1.27e-06	418	66	8	34709266
Pubmed	Comparative mapping of the DiGeorge syndrome region in mouse shows inconsistent gene order and differential degree of gene conservation.	DGCR6 SEPTIN5 DGCR6L	1.42e-06	12	66	3	9383280
Pubmed	TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity.	BUB1B TP73	3.55e-06	2	66	2	19139399
Pubmed	Dysregulation of DGCR6 and DGCR6L: psychopathological outcomes in chromosome 22q11.2 deletion syndrome.	DGCR6 DGCR6L	3.55e-06	2	66	2	22832905
Pubmed	Molecular approach in the study of Alström syndrome: analysis of ten Spanish families.	RPGRIP1L ALMS1	3.55e-06	2	66	2	22876109
Pubmed	Biochemical characterisation of the proteins encoded by the DiGeorge critical region 6 (DGCR6) genes.	DGCR6 DGCR6L	3.55e-06	2	66	2	15821931
Pubmed	Two functional copies of the DGCR6 gene are present on human chromosome 22q11 due to a duplication of an ancestral locus.	DGCR6 DGCR6L	3.55e-06	2	66	2	11157784
Pubmed	A mouse gene (Dgcr6) related to the Drosophila gonadal gene is expressed in early embryogenesis and is the homolog of a human gene deleted in DiGeorge syndrome.	DGCR6 DGCR6L	3.55e-06	2	66	2	9605865
Pubmed	Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation.	PIK3CA ATM	3.55e-06	2	66	2	16728507
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	ALMS1 TNRC6B BIRC6 RPS6KC1	5.32e-06	60	66	4	34761192
Pubmed	Cloning and comparative mapping of the DiGeorge syndrome critical region in the mouse.	DGCR6 SEPTIN5 DGCR6L	7.27e-06	20	66	3	9740669
Pubmed	JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study.	JCAD PIK3CA	1.06e-05	3	66	2	36469488
Pubmed	Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia.	TYK2 STAT2	1.06e-05	3	66	2	35708626
Pubmed	A preliminary study of the relationship between promoter methylation of the ABCG1, GALNT2 and HMGCR genes and coronary heart disease.	GALNT2 HMGCR	1.06e-05	3	66	2	25084356
Pubmed	Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents.	BUB1B ATM	1.06e-05	3	66	2	34545188
Pubmed	p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor.	STAT2 TP73	1.06e-05	3	66	2	21399658
Pubmed	Predictive Value of the TP53/PIK3CA/ATM Mutation Classifier for Patients With Bladder Cancer Responding to Immune Checkpoint Inhibitor Therapy.	PIK3CA ATM	1.06e-05	3	66	2	34421886
Pubmed	Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway.	ATM TP73	1.06e-05	3	66	2	20194434
Pubmed	The novel human platelet septin SEPT8 is an interaction partner of SEPT4.	SEPTIN5 SEPTIN4	1.06e-05	3	66	2	15116257
Pubmed	The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals.	TYK2 STAT2	1.06e-05	3	66	2	8605877
Pubmed	Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol.	SEPTIN5 SEPTIN4	1.06e-05	3	66	2	15214843
Pubmed	[P53-independent apoptosis through a novel ATM/IKK-alpha/p73-mediated apoptotic pathway].	ATM TP73	1.06e-05	3	66	2	18575226
Pubmed	Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region.	DGCR6 SEPTIN5 DGCR6L	2.07e-05	28	66	3	10963672
Pubmed	Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.	TYK2 STAT2	2.12e-05	4	66	2	23653476
Pubmed	TRIM10 binds to IFN-α/β receptor 1 to negatively regulate type I IFN signal transduction.	TYK2 STAT2	2.12e-05	4	66	2	33811647
Pubmed	SARS-CoV-2 N protein antagonizes type I interferon signaling by suppressing phosphorylation and nuclear translocation of STAT1 and STAT2.	TYK2 STAT2	2.12e-05	4	66	2	32953130
Pubmed	Impaired type I IFN-induced Jak/STAT signaling in FA-C cells and abnormal CD4+ Th cell subsets in Fancc-/- mice.	TYK2 STAT2	2.12e-05	4	66	2	15356134
Pubmed	SEPT5_v2 is a parkin-binding protein.	SEPTIN5 SEPTIN4	2.12e-05	4	66	2	14559152
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TYK2 MTMR12 GALNT2 BUB1B ANKIB1 SIN3A RGS3 FAM111B	3.16e-05	650	66	8	38777146
Pubmed	Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2.	DGCR6 SEPTIN5 DGCR6L	3.42e-05	33	66	3	10704284
Pubmed	Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.	SEPTIN5 SEPTIN4	3.53e-05	5	66	2	17296554
Pubmed	Integration of cytogenetic with recombinational and physical maps of mouse chromosome 16.	DGCR6 DGCR6L	3.53e-05	5	66	2	10395793
Pubmed	Alterations in p53, BRCA1, ATM, PIK3CA, and HER2 genes and their effect in modifying clinicopathological characteristics and overall survival of Bulgarian patients with breast cancer.	PIK3CA ATM	3.53e-05	5	66	2	20177704
Pubmed	Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein.	TYK2 STAT2	3.53e-05	5	66	2	8605876
Pubmed	Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.	DGCR6 SEPTIN5 DGCR6L	4.84e-05	37	66	3	10337614
Pubmed	Effect of DNA repair protein Rad18 on viral infection.	POLH APOBEC3G	5.29e-05	6	66	2	16710452
Pubmed	Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation.	DGCR6 SEPTIN5 DGCR6L	6.61e-05	41	66	3	25452572
Pubmed	Differential localization of septins in the mouse brain.	SEPTIN5 SEPTIN4	7.40e-05	7	66	2	11064363
Pubmed	p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes.	ATM TP73	7.40e-05	7	66	2	28617799
Pubmed	Damage control: how HIV survives the editor APOBEC3G.	APOBEC3G ATM	7.40e-05	7	66	2	21934670
Pubmed	A comprehensive analysis of 22q11 gene expression in the developing and adult brain.	DGCR6 SEPTIN5 DGCR6L	8.75e-05	45	66	3	14614146
Pubmed	The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells.	APOBEC3G ATM	9.86e-05	8	66	2	21874023
Pubmed	Running loose or getting lost: how HIV-1 counters and capitalizes on APOBEC3-induced mutagenesis through its Vif protein.	APOBEC3G ATM	9.86e-05	8	66	2	23202519
Pubmed	Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome.	DGCR6 SEPTIN5 DGCR6L	9.97e-05	47	66	3	24357327
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TYK2 RLF GALNT2 SEPTIN5 SLC16A14 ANKIB1 TNRC6B LRP5 CHD9 ZMIZ1 ZNF44	1.05e-04	1489	66	11	28611215
Pubmed	Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas.	PIK3CA ATM	1.27e-04	9	66	2	20838624
Pubmed	Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.	SEPTIN5 SEPTIN4	1.27e-04	9	66	2	18809578
Pubmed	JAK-STAT signaling maintains homeostasis in T cells and macrophages.	TYK2 STAT2	1.58e-04	10	66	2	38658806
Pubmed	JAK-STAT and bone metabolism.	TYK2 STAT2	1.58e-04	10	66	2	24069548
Pubmed	The septin CDCrel-1 is dispensable for normal development and neurotransmitter release.	SEPTIN5 SEPTIN4	1.58e-04	10	66	2	11739749
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK3 JCAD SIN3A ATM TEX14 TP73	1.68e-04	430	66	6	35044719
Pubmed	Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.	POLH BUB1B ATM	2.17e-04	61	66	3	27694478
Pubmed	Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.	TYK2 STAT2	2.73e-04	13	66	2	19434718
Pubmed	High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.	ANG SIN3A	2.73e-04	13	66	2	17670746
Pubmed	Genome-wide association study of antiphospholipid antibodies.	DSTN PELO	2.73e-04	13	66	2	23509613
Pubmed	RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.	RPGRIP1L DSC3	4.18e-04	16	66	2	30689641
Pubmed	Localization of septin proteins in the mouse cochlea.	SEPTIN5 SEPTIN4	4.18e-04	16	66	2	22575789
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	RPGRIP1L ALMS1 BUB1B TNRC6B	4.23e-04	184	66	4	32908313
Pubmed	Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.	BUB1B SIN3A	4.74e-04	17	66	2	14519686
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NPTN RPGRIP1L ALMS1 TNRC6B HMGCR BIRC6 STAT2	4.76e-04	733	66	7	34672954
Pubmed	Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer.	RNF135 ZBTB1	5.94e-04	19	66	2	15334068
Pubmed	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	TYK2 STAT2	5.94e-04	19	66	2	20953190
Pubmed	Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects.	ANG PIK3CA	5.94e-04	19	66	2	25958091
Pubmed	Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.	GALNT2 HMGCR	5.94e-04	19	66	2	19148283
Pubmed	Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.	TYK2 STAT2	5.94e-04	19	66	2	32075740
Pubmed	TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B.	TYK2 STAT2	6.59e-04	20	66	2	11694501
Pubmed	Meta-analysis identifies four new loci associated with testicular germ cell tumor.	SEPTIN4 TEX14	6.59e-04	20	66	2	23666239
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TMEFF1 DOCK3 JCAD DGCR6 P4HTM GALNT2 CHD9 ZNF214 ATM	6.95e-04	1285	66	9	35914814
Pubmed	BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer	PIK3CA ATM	7.28e-04	21	66	2	20301425
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RPGRIP1L PELO ALMS1 STAT2 TP73 FAM111B	8.76e-04	588	66	6	38580884
Pubmed	The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.	PELO SEPTIN5 BUB1B TP73	9.28e-04	227	66	4	26410627
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	MAGEA11 DGCR6 SEPTIN5 ZBTB1 DGCR6L	1.01e-03	402	66	5	24722188
Pubmed	Substrate specificities and identification of putative substrates of ATM kinase family members.	PIK3CA ATM	1.03e-03	25	66	2	10608806
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DOCK3 ALMS1 CHD9	1.04e-03	104	66	3	9205841
Pubmed	Type I Interferons Ameliorate Zinc Intoxication of Candida glabrata by Macrophages and Promote Fungal Immune Evasion.	TYK2 STAT2	1.21e-03	27	66	2	32428860
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TYK2 PELO ALMS1 TNRC6B CHD9 SIN3A SREK1 TP73	1.21e-03	1116	66	8	31753913
Pubmed	The protein kinase complement of the human genome.	TEX14 RPS6KC1	1.30e-03	28	66	2	12471243
Pubmed	Vpr and its interactions with cellular proteins.	APOBEC3G ATM	1.30e-03	28	66	2	20012529
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	GALNT2 HMGCR	1.39e-03	29	66	2	20167577
Pubmed	Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization.	DGCR6 DGCR6L	1.49e-03	30	66	2	9405660
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	JCAD MTMR12 ALMS1 TNRC6B BIRC6	1.59e-03	446	66	5	24255178
Pubmed	A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers.	BUB1B ATM TP73	1.60e-03	121	66	3	19789190
Pubmed	Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling.	PIK3CA LRP5	1.70e-03	32	66	2	34193412
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	DSTN SIN3A SREK1 BIRC6	1.73e-03	269	66	4	29511261
Pubmed	Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.	GALNT2 HMGCR	1.80e-03	33	66	2	18193044
Pubmed	Lynch Syndrome	PIK3CA BUB1B	1.80e-03	33	66	2	20301390
Pubmed	DHHC protein family targets different subsets of glioma stem cells in specific niches.	PIK3CA SIN3A	1.80e-03	33	66	2	30658672
Cytoband	22q11.21	DGCR6 SEPTIN5 DGCR6L	5.63e-04	111	66	3	22q11.21
Cytoband	16q12.2	RPGRIP1L CHD9	6.47e-04	26	66	2	16q12.2
Cytoband	17q22	SEPTIN4 TEX14	1.85e-03	44	66	2	17q22
Cytoband	9q32	RGS3 ZFP37	2.11e-03	47	66	2	9q32
Cytoband	Ensembl 112 genes in cytogenetic band chr9q32	RGS3 ZFP37	2.38e-03	50	66	2	chr9q32
GeneFamily	Septins	SEPTIN5 SEPTIN4	4.04e-04	13	42	2	732
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZNF695 ZNF214 ZBTB1 ZSCAN23 ZFP37 ZNF44	1.21e-03	718	42	7	28
GeneFamily	Ankyrin repeat domain containing	CLIP3 TRPA1 ASB10 ANKIB1	2.35e-03	242	42	4	403
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RPGRIP1L RGS3	3.16e-03	36	42	2	823
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	DOCK3 ALMS1 ATM TEX14 LARP1B	2.34e-05	115	63	5	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PELO DSC3 SEPTIN4 KCNJ8 UNC13C	4.66e-06	165	66	5	369d77a80d6401e85ea3121ab5a252f67d5f157e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 DDIAS BUB1B TP73 FAM111B	5.23e-06	169	66	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	Influenza_Severe-Plasmablast\|Influenza_Severe / Disease group and Cell class	SLC16A14 BUB1B UNC13C SEMA3G ZSCAN23	6.20e-06	175	66	5	3f9b9793d3d1b7a9b97899272b6a0d37b05c11d1
ToppCell	Influenza_Severe-Plasmablast\|World / Disease group and Cell class	SLC16A14 BUB1B UNC13C SEMA3G ZSCAN23	6.20e-06	175	66	5	14df8fc6f6beae1be7b7bd5837546d1ac1239a6f
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	JCAD ASB10 APOBEC3G ATM RGS3	7.30e-06	181	66	5	9c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCell	Influenza-Influenza_Severe-Lymphocyte-B-Plasmablast\|Influenza_Severe / Disease, condition lineage and cell class	SLC16A14 BUB1B LRP5 SEMA3G TP73	1.10e-05	197	66	5	9108edafbf5744ed65f556bcbbf819a9b71176a9
ToppCell	VE-Treg-naive_CD4\|VE / Condition, Cell_class and T cell subcluster	PIK3CA SEMA3G ZBTB1 DGCR6L	8.48e-05	156	66	4	6501baf73616e702946de9fb13d267e30a68888b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP8B3 BUB1B TP73 FAM111B	8.48e-05	156	66	4	b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DDIAS DGCR6 TEX14 FAM111B	1.08e-04	166	66	4	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	DDIAS DGCR6 TEX14 FAM111B	1.10e-04	167	66	4	7efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLIP3 SEPTIN5 SEPTIN4 KCNJ8	1.10e-04	167	66	4	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	facs-Spleen-nan-3m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTN GALNT2 KCNJ8 RGS3	1.13e-04	168	66	4	74dc46738f1d0a448df6c9b8288b515d92697792
ToppCell	severe_influenza-Plasmablast\|severe_influenza / disease group, cell group and cell class (v2)	SLC16A14 BUB1B SEMA3G ZSCAN23	1.29e-04	174	66	4	8c6c4d794373e774ecb3382cb7163b4246b98780
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	JCAD SLC16A14 SEMA3G TEX14	1.32e-04	175	66	4	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A14 BUB1B UNC13C RGS3	1.32e-04	175	66	4	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PELO SEPTIN4 KCNJ8 TEX14	1.41e-04	178	66	4	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	JCAD SLC16A14 UNC13C RGS3	1.47e-04	180	66	4	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	JCAD SLC16A14 UNC13C RGS3	1.47e-04	180	66	4	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP8B3 ALMS1 BUB1B FAM111B	1.50e-04	181	66	4	e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSTN SEPTIN5 BUB1B LARP1B	1.50e-04	181	66	4	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSTN SEPTIN5 BUB1B LARP1B	1.50e-04	181	66	4	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLH BUB1B UNC13C RGS3	1.54e-04	182	66	4	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALMS1 DSC3 ANKIB1 UNC13C	1.54e-04	182	66	4	9174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLH BUB1B TP73 FAM111B	1.63e-04	185	66	4	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PELO SEPTIN4 KCNJ8 UNC13C	1.67e-04	186	66	4	0b2ce9b8a4382d583240647217ad5e2d3fa555c1
ToppCell	10x5'v1-week_12-13-Mesenchymal_myocytic-stroma-muscle\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CLIP3 DSTN UNC13C RGS3	1.67e-04	186	66	4	fbc4ba4a7a8e5902a1b0add52ece0d6da85a8a5f
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD CLIP3 DSTN KCNJ8	1.70e-04	187	66	4	e1b41560c26795a7d353b9468b1bb6fc7c6b379e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLH BUB1B TP73 FAM111B	1.70e-04	187	66	4	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLH BUB1B UNC13C FAM111B	1.70e-04	187	66	4	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	15-Distal-Mesenchymal-Pericyte\|Distal / Age, Tissue, Lineage and Cell class	PELO SEPTIN4 KCNJ8 RGS3	1.74e-04	188	66	4	4963382e54aac06bf5047c7d725393db70667ee7
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RLF TNRC6B SREK1 BIRC6	1.74e-04	188	66	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	11.5-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	PELO SEPTIN5 SEPTIN4 KCNJ8	1.74e-04	188	66	4	916971d8660fd20f616346953874e89d2cd13e88
ToppCell	severe_COVID-19-Plasmablast\|severe_COVID-19 / disease group, cell group and cell class (v2)	SLC16A14 BUB1B UNC13C TP73	1.77e-04	189	66	4	953143b2c2e87a4d8ef033a5fbb155fe62e9c78e
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	JCAD ASB10 APOBEC3G ATM	1.77e-04	189	66	4	3e148accffc6ab249fb0dff7f3bf5a7fff9da773
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 ANKIB1 CHD9 LARP1B	1.85e-04	191	66	4	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 ANKIB1 CHD9 LARP1B	1.85e-04	191	66	4	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 ANKIB1 CHD9 LARP1B	1.85e-04	191	66	4	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPGRIP1L ANG ALMS1 TP73	1.96e-04	194	66	4	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	11.5-Distal-Mesenchymal-Pericyte\|Distal / Age, Tissue, Lineage and Cell class	PELO SEPTIN4 KCNJ8 RGS3	1.96e-04	194	66	4	08701590496cf85ff790e54a81493c61177e76ff
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ATP8B3 BUB1B TEX14 FAM111B	2.04e-04	196	66	4	34bd155e6d848eb53d613997c0e244535de30ba3
ToppCell	facs-Brain_Non-Myeloid\|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEFF1 JCAD CLIP3 SEPTIN4	2.08e-04	197	66	4	a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PELO SEPTIN4 KCNJ8 RGS3	2.12e-04	198	66	4	76d46950c11cb4708866db0da54ce00d5c0adab8
ToppCell	MS-cycling\|MS / Condition, Cell_class and T cell subcluster	DDIAS BUB1B TP73 FAM111B	2.12e-04	198	66	4	0c22f2cc0e5ca91cabcd4aac2b9ef05af47e967f
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PELO SEPTIN4 KCNJ8 RGS3	2.12e-04	198	66	4	72aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCell	MS-cycling-\|MS / Condition, Cell_class and T cell subcluster	DDIAS BUB1B TP73 FAM111B	2.12e-04	198	66	4	19c5d6b65de490118574b1f86b45c58b3a51df7f
ToppCell	severe-Plasmablast\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLC16A14 TEX14 LARP1B TP73	2.16e-04	199	66	4	6ee4c2e6049860071169366b7e662d5c1a3cc54b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BUB1B RGS3 TP73 FAM111B	2.16e-04	199	66	4	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DDIAS BUB1B TP73 FAM111B	2.20e-04	200	66	4	63f9481059be608ddc9fe9c7a8f8503fce9755dd
ToppCell	Transverse-(2)_B_cell-(24)_B_cell_cycling\|Transverse / shred on region, Cell_type, and subtype	DDIAS ZNF695 BUB1B FAM111B	2.20e-04	200	66	4	e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCell	Transverse-B_cell-B_cell_cycling\|Transverse / Region, Cell class and subclass	DDIAS ZNF695 BUB1B FAM111B	2.20e-04	200	66	4	0e270f8019d9f22068ca426d661937262a5cd331
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3\|Control_saline / Treatment groups by lineage, cell group, cell type	DSTN PELO SEPTIN5 ASB10	2.20e-04	200	66	4	b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATM SREK1 BIRC6 STAT2	2.20e-04	200	66	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	PSB-critical-LOC-Lymphoid-Treg\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DDIAS DSC3 BUB1B FAM111B	2.20e-04	200	66	4	3e3de496508efb2f95e5e8684f97687381e96493
Disease	proline measurement, amino acid measurement	DGCR6 DGCR6L	4.61e-05	5	64	2	EFO_0005134, EFO_0009773
Disease	Growth Disorders	PIK3CA RNF135 BUB1B	6.60e-05	36	64	3	C0018273
Disease	disease of cellular proliferation (implicated_via_orthology)	TYK2 ATM	9.66e-05	7	64	2	DOID:14566 (implicated_via_orthology)
Disease	female breast cancer (is_implicated_in)	POLH ATM	1.29e-04	8	64	2	DOID:0050671 (is_implicated_in)
Disease	colorectal cancer (is_implicated_in)	PIK3CA BUB1B ATM TP73	1.41e-04	121	64	4	DOID:9256 (is_implicated_in)
Disease	Shortened QT interval	KCNJ8 LRP5	2.52e-04	11	64	2	C0151879
Disease	phospholipids in small LDL measurement	GALNT2 PELO HMGCR	2.90e-04	59	64	3	EFO_0022297
Disease	psoriasis vulgaris	TYK2 ZMIZ1 STAT2	3.20e-04	61	64	3	EFO_1001494
Disease	Microcephaly	BUB1B SIN3A ZMIZ1	4.22e-04	67	64	3	C0025958
Disease	N-acetylmethionine measurement	DOCK3 ALMS1	4.77e-04	15	64	2	EFO_0021427
Disease	nucleotide measurement	GALNT2 UNC13C HMGCR	5.43e-04	73	64	3	EFO_0010513
Disease	psoriasis, type 2 diabetes mellitus	TYK2 ZMIZ1 STAT2	5.88e-04	75	64	3	EFO_0000676, MONDO_0005148
Disease	Parkinson's disease (is_implicated_in)	ANG HMGCR ATM	6.11e-04	76	64	3	DOID:14330 (is_implicated_in)
Disease	Benign neoplasm of stomach	PIK3CA ATM	6.17e-04	17	64	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	PIK3CA ATM	6.17e-04	17	64	2	C0496905
Disease	Carcinoma in situ of stomach	PIK3CA ATM	6.17e-04	17	64	2	C0154060
Disease	BREAST CANCER	PIK3CA ATM	9.47e-04	21	64	2	114480
Disease	Stomach Carcinoma	PIK3CA ATM	9.47e-04	21	64	2	C0699791
Disease	Adenocarcinoma of large intestine	TYK2 PIK3CA ATM	1.20e-03	96	64	3	C1319315
Disease	lung squamous cell carcinoma (is_implicated_in)	ATM TP73	1.24e-03	24	64	2	DOID:3907 (is_implicated_in)
Disease	corpus collosum mid-posterior volume measurement	UNC13C AGBL2	1.35e-03	25	64	2	EFO_0010300
Disease	proline measurement	DGCR6 DGCR6L	1.46e-03	26	64	2	EFO_0009773
Disease	Colorectal cancer	PIK3CA BUB1B	1.57e-03	27	64	2	cv:C0346629
Disease	Hereditary non-polyposis colorectal cancer syndrome	PIK3CA ATM	1.57e-03	27	64	2	C1112155
Disease	COLORECTAL CANCER	PIK3CA BUB1B	1.57e-03	27	64	2	114500
Disease	Malignant tumor of breast	PIK3CA ATM	1.57e-03	27	64	2	cv:C0006142
Disease	Neoplasm of the large intestine	PIK3CA BUB1B	1.57e-03	27	64	2	cv:C0009404
Disease	Breast neoplasm	PIK3CA ATM	1.57e-03	27	64	2	cv:C1458155
Disease	cholesterol to total lipids in medium LDL percentage	GALNT2 HMGCR	1.57e-03	27	64	2	EFO_0022238
Disease	Familial cancer of breast	PIK3CA ATM	1.57e-03	27	64	2	cv:C0346153
Disease	lung small cell carcinoma (is_implicated_in)	ATM TP73	1.69e-03	28	64	2	DOID:5409 (is_implicated_in)
Disease	Hereditary Nonpolyposis Colorectal Cancer	PIK3CA ATM	1.81e-03	29	64	2	C1333990
Disease	Ventricular Dysfunction, Left	PIK3CA ATM	1.94e-03	30	64	2	C0242698
Disease	Breast Cancer, Familial	PIK3CA ATM	1.94e-03	30	64	2	C0346153
Disease	total cholesterol measurement, low density lipoprotein cholesterol measurement	GALNT2 PELO HMGCR	1.97e-03	114	64	3	EFO_0004574, EFO_0004611
Disease	Severe Congenital Microcephaly	BUB1B SIN3A	2.07e-03	31	64	2	C3853041
Disease	Polydactyly	RPGRIP1L ALMS1 PIK3CA	2.12e-03	117	64	3	C0152427

Protein segments in the cluster

Peptide	Gene	Start	Entry
GCQRLPEDQRKKVHQ	PRPF4B	961	Q13523
NDSHIRRPCQLKDLN	nan	96	A8MT66
RNRIHDPYDCNKNNQ	BUB1B	891	O60566
KTLCQPNEHNNRIEA	CCDC186	51	Q7Z3E2
QDKLRRHHVPQQCNK	BIRC6	3661	Q9NR09
NQRRGFLCNQAPHKH	APOBEC3G	236	Q9HC16
DQDKQRPLHLACRRG	ASB10	291	Q8WXI3
NIDRERQGHQNRMCP	ALMS1	4081	Q8TCU4
LGRDGNPNKRNVHNE	ANKIB1	66	Q9P2G1
GRHKSDRAINNRPCQ	ATP8B3	206	O60423
LRQKHQEAQQACRPH	DGCR6	96	Q14129
IKHECQANGPEDLNR	DSTN	131	P60981
RRHCDKGNLRVKPQQ	P4HTM	401	Q9NXG6
LNINPDRKEHNCREE	R3HCC1L	71	Q7Z5L2
REKNCTHGVQARPEQ	RGS3	406	P49796
GACNLAHKNIREQGR	KCNJ8	41	Q15842
RSQHCKPEEGLQAQE	MAGEA11	116	P43364
RRKANENAGLQECPR	RPGRIP1L	161	Q68CZ1
DRCNHLRQNDKEEVP	MTMR12	436	Q9C0I1
HREGIVCRDLNPNNI	RPS6KC1	921	Q96S38
IRCIKPNEHQQRGQF	MYO1A	586	Q9UBC5
ACKDNPGENARQLAR	HMGCR	826	P04035
PQQENRAHCRQEDVG	JCAD	866	Q9P266
RAIPDTRHDQCQRKQ	GALNT2	116	Q10471
NPKIECANLDGQERR	LRP5	481	O75197
RKLQCDSQAPNNHLL	DDIAS	191	Q8IXT1
CENKNGNPHRENLRI	ANG	81	P03950
NPAHQLGNLRLEECR	PIK3CA	756	P42336
VKRCPNHELGRDFNE	TP73	191	O15350
NLHNADQPLRVRGCI	EIF3CL	431	B5ME19
HPTLNADDQECKRNL	ATM	2981	Q13315
LQAQARCHRIGQNKA	CHD9	1286	Q3L8U1
KSHAQEAVRGQRCPQ	DOCK3	921	Q8IZD9
QPRLGEKLHRCNQNE	DSC3	826	Q14574
HVRKNNPQCLLNGSL	AGBL2	46	Q5U5Z8
LRQKHQEAQQACRPH	DGCR6L	96	Q9BY27
QAQCLRKDPGANNHL	GPR142	81	Q7Z601
CLLEHGANPALRNRK	CLIP3	216	Q96DZ5
SKEDGHILRQCENPN	FAM111B	166	Q6SJ93
DRDLPGSLQCQLQHK	EFCAB3	26	Q8N7B9
LHQLARENGDPQLCD	FTH1P19	81	P0C7X4
RCQPEANKPTHNNRR	LARP1B	101	Q659C4
TCRQGAAQQPHLRKN	RNF135	61	Q8IUD6
RQADKHNIPRICFLN	GFM2	181	Q969S9
QQQKACIRAPIDHGL	STAT2	241	P52630
NNDCDSDQHGRQPRL	TEX14	1011	Q8IWB6
SGLNRKNIQDNRVHC	SEPTIN4	241	O43236
SGLNRKNIQDNRVHC	SEPTIN5	141	Q99719
DLQAQECPDQAGHRK	SLC16A14	261	Q7RTX9
KPQRPSQNGCQIRRH	SIN3A	416	Q96ST3
NIPRKRKGNCSQHDR	PELO	166	Q9BRX2
VEQRQNPHLRNKPCA	POLH	21	Q9Y253
PRTEENKIQHNGNCQ	SREK1	481	Q8WXA9
QNNRIELLNHPVCKE	TRPA1	691	O75762
QQQRIHIGENPYQCK	ZNF695	201	Q8IW36
QRIGHQRDCPNAKPR	UNC13C	361	Q8NB66
GEKQDCINQPHLLNQ	RLF	846	Q13129
CRASNDPKRNDLRQN	NPTN	116	Q9Y639
RQLQEHAQRCGEPQD	ZBTB1	461	Q9Y2K1
RQDIRHGNPALQCLG	SEMA3G	561	Q9NS98
PKNNRGRRQKQNLGH	TMEFF1	356	Q8IYR6
QNLDLPDHSRNCVKR	ZFP37	186	Q9Y6Q3
DDQHQNLRRNPRCDV	ZNF44	101	P15621
NSRCVFHKRNQPGEN	ZNF214	231	Q9UL59
TNDRLQCIKQHLQNP	ZMIZ1	11	Q9ULJ6
RCQQDHKVLLKRGQP	TNRC6B	96	Q9UPQ9
ENKNLVHGNVCGRNI	TYK2	726	P29597
GPREALQRLQELCHQ	ZSCAN23	61	Q3MJ62