Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein tyrosine kinase activity	ERBB4 HCK ITK EPHA5 EPHA7	1.62e-06	145	28	5	GO:0004713
GeneOntologyMolecularFunction	GPI-linked ephrin receptor activity	EPHA5 EPHA7	3.96e-05	7	28	2	GO:0005004
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	ERBB4 EPHA5 EPHA7	1.02e-04	65	28	3	GO:0004714
GeneOntologyMolecularFunction	protein kinase activity	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	1.54e-04	600	28	6	GO:0004672
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHA5 EPHA7	1.97e-04	15	28	2	GO:0005005
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	ERBB4 EPHA5 EPHA7	2.26e-04	85	28	3	GO:0019199
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ANKK1 ERBB4 HCK POLH ITK EPHA5 EPHA7	2.45e-04	938	28	7	GO:0016772
GeneOntologyMolecularFunction	ephrin receptor activity	EPHA5 EPHA7	3.19e-04	19	28	2	GO:0005003
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	3.79e-04	709	28	6	GO:0016773
GeneOntologyMolecularFunction	kinase activity	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	5.63e-04	764	28	6	GO:0016301
GeneOntologyMolecularFunction	growth factor binding	ERBB4 EPHA5 EPHA7	1.33e-03	156	28	3	GO:0019838
GeneOntologyMolecularFunction	non-membrane spanning protein tyrosine kinase activity	HCK ITK	1.89e-03	46	28	2	GO:0004715
GeneOntologyCellularComponent	neuromuscular junction	DLGAP3 ERBB4 UTRN EPHA7	1.45e-05	112	28	4	GO:0031594
GeneOntologyCellularComponent	caveola	SELE ERBB4 HCK	4.33e-04	111	28	3	GO:0005901
GeneOntologyCellularComponent	plasma membrane raft	SELE ERBB4 HCK	9.81e-04	147	28	3	GO:0044853
Domain	Pkinase_Tyr	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	3.21e-08	129	28	6	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	4.81e-08	138	28	6	IPR001245
Domain	TyrKc	ERBB4 HCK ITK EPHA5 EPHA7	1.87e-07	88	28	5	SM00219
Domain	Tyr_kinase_cat_dom	ERBB4 HCK ITK EPHA5 EPHA7	1.87e-07	88	28	5	IPR020635
Domain	PROTEIN_KINASE_TYR	ERBB4 HCK ITK EPHA5 EPHA7	3.04e-07	97	28	5	PS00109
Domain	Tyr_kinase_AS	ERBB4 HCK ITK EPHA5 EPHA7	3.04e-07	97	28	5	IPR008266
Domain	PROTEIN_KINASE_ATP	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	5.07e-05	459	28	6	PS00107
Domain	Prot_kinase_dom	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	7.21e-05	489	28	6	IPR000719
Domain	PROTEIN_KINASE_DOM	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	7.54e-05	493	28	6	PS50011
Domain	Kinase-like_dom	ANKK1 ERBB4 HCK ITK EPHA5 EPHA7	1.27e-04	542	28	6	IPR011009
Domain	-	HERC2 EPHA5 EPHA7	1.75e-04	73	28	3	2.60.120.260
Domain	RECEPTOR_TYR_KIN_V_2	EPHA5 EPHA7	1.95e-04	14	28	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA5 EPHA7	1.95e-04	14	28	2	PS00790
Domain	EphA2_TM	EPHA5 EPHA7	1.95e-04	14	28	2	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHA5 EPHA7	1.95e-04	14	28	2	IPR016257
Domain	Eph_TM	EPHA5 EPHA7	1.95e-04	14	28	2	IPR027936
Domain	Ephrin_rcpt_lig-bd_dom	EPHA5 EPHA7	1.95e-04	14	28	2	IPR001090
Domain	Tyr_kinase_rcpt_V_CS	EPHA5 EPHA7	1.95e-04	14	28	2	IPR001426
Domain	EPH_LBD	EPHA5 EPHA7	1.95e-04	14	28	2	PS51550
Domain	EPH_lbd	EPHA5 EPHA7	1.95e-04	14	28	2	SM00615
Domain	Ephrin_lbd	EPHA5 EPHA7	1.95e-04	14	28	2	PF01404
Domain	Protein_kinase_ATP_BS	ERBB4 HCK ITK EPHA5 EPHA7	2.24e-04	379	28	5	IPR017441
Domain	ZF_ZZ_2	HERC2 UTRN	3.27e-04	18	28	2	PS50135
Domain	ZF_ZZ_1	HERC2 UTRN	3.27e-04	18	28	2	PS01357
Domain	ZZ	HERC2 UTRN	3.27e-04	18	28	2	PF00569
Domain	Znf_ZZ	HERC2 UTRN	3.65e-04	19	28	2	IPR000433
Domain	ZnF_ZZ	HERC2 UTRN	3.65e-04	19	28	2	SM00291
Domain	Galactose-bd-like	HERC2 EPHA5 EPHA7	3.69e-04	94	28	3	IPR008979
Domain	SH2	TNS1 HCK ITK	4.56e-04	101	28	3	PF00017
Domain	SH2	TNS1 HCK ITK	5.85e-04	110	28	3	SM00252
Domain	SH2	TNS1 HCK ITK	6.01e-04	111	28	3	PS50001
Domain	SH2	TNS1 HCK ITK	6.17e-04	112	28	3	IPR000980
Domain	-	TNS1 HCK ITK	6.17e-04	112	28	3	3.30.505.10
Domain	Ephrin_rec_like	EPHA5 EPHA7	6.36e-04	25	28	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHA5 EPHA7	6.36e-04	25	28	2	IPR011641
Domain	Growth_fac_rcpt_	ERBB4 EPHA5 EPHA7	1.61e-03	156	28	3	IPR009030
Domain	WW	SETD2 UTRN	2.25e-03	47	28	2	PF00397
Domain	WW	SETD2 UTRN	2.34e-03	48	28	2	SM00456
Domain	WW_DOMAIN_2	SETD2 UTRN	2.64e-03	51	28	2	PS50020
Domain	WW_DOMAIN_1	SETD2 UTRN	2.64e-03	51	28	2	PS01159
Domain	WW_dom	SETD2 UTRN	2.74e-03	52	28	2	IPR001202
Domain	SAM_1	EPHA5 EPHA7	4.64e-03	68	28	2	PF00536
Domain	EGF-like_CS	SELE EPHA5 EPHA7	6.83e-03	261	28	3	IPR013032
Domain	EGF_2	SELE EPHA5 EPHA7	7.12e-03	265	28	3	PS01186
Domain	SAM	EPHA5 EPHA7	7.66e-03	88	28	2	SM00454
Domain	SAM_DOMAIN	EPHA5 EPHA7	8.88e-03	95	28	2	PS50105
Pathway	PID_EPHA_FWDPATHWAY	HCK EPHA5 EPHA7	2.51e-05	34	24	3	M177
Pubmed	The protein tyrosine kinase family of the human genome.	ERBB4 HCK ITK EPHA5 EPHA7	6.45e-09	83	28	5	11114734
Pubmed	Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.	ERBB4 TNS1 HCK ITK	4.37e-07	77	28	4	22973453
Pubmed	EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac1 activation.	EPHA5 EPHA7	1.87e-06	3	28	2	27988259
Pubmed	ErbB4 regulation of a thalamic reticular nucleus circuit for sensory selection.	ERBB4 SST	1.87e-06	3	28	2	25501036
Pubmed	cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.	EPHA5 EPHA7	3.75e-06	4	28	2	7898931
Pubmed	The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.	HCK ITK	6.24e-06	5	28	2	24722985
Pubmed	Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits.	ERBB4 SST	6.24e-06	5	28	2	28817803
Pubmed	A Central Extended Amygdala Circuit That Modulates Anxiety.	ERBB4 SST	6.24e-06	5	28	2	29844022
Pubmed	Clinical significance of ephrin (eph)-A1, -A2, -a4, -a5 and -a7 receptors in pancreatic ductal adenocarcinoma.	EPHA5 EPHA7	6.24e-06	5	28	2	19949912
Pubmed	Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes.	HCK ITK	9.36e-06	6	28	2	10586033
Pubmed	Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system.	EPHA5 EPHA7	9.36e-06	6	28	2	15996548
Pubmed	Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes.	EPHA5 EPHA7	9.36e-06	6	28	2	12895420
Pubmed	A novel spinal neuron connection for heat sensation.	ERBB4 SST	1.31e-05	7	28	2	35561677
Pubmed	Generation of ventralized human thalamic organoids with thalamic reticular nucleus.	ERBB4 SST	1.31e-05	7	28	2	37019105
Pubmed	PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.	SELE HCK	1.74e-05	8	28	2	18794338
Pubmed	Mistargeting hippocampal axons by expression of a truncated Eph receptor.	EPHA5 EPHA7	1.74e-05	8	28	2	12124402
Pubmed	Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.	EPHA5 EPHA7	1.74e-05	8	28	2	10774725
Pubmed	A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis.	EPHA5 EPHA7	1.74e-05	8	28	2	19036963
Pubmed	Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.	EPHA5 EPHA7	2.24e-05	9	28	2	11403717
Pubmed	Topographic guidance labels in a sensory projection to the forebrain.	EPHA5 EPHA7	2.24e-05	9	28	2	9883724
Pubmed	Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.	TNS1 HCK ITK	2.80e-05	73	28	3	24728074
Pubmed	Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate.	EPHA5 EPHA7	2.80e-05	10	28	2	25073978
Pubmed	EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.	EPHA5 EPHA7	2.80e-05	10	28	2	28197551
Pubmed	HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.	EPHA5 EPHA7	2.80e-05	10	28	2	17304517
Pubmed	ErbB4 modulates tubular cell polarity and lumen diameter during kidney development.	ERBB4 SLC12A3	2.80e-05	10	28	2	22076439
Pubmed	Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.	HCK ITK	2.80e-05	10	28	2	18155796
Pubmed	Quantitative assessment of computational models for retinotopic map formation.	EPHA5 EPHA7	2.80e-05	10	28	2	25367067
Pubmed	EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes.	EPHA5 EPHA7	2.80e-05	10	28	2	16547242
Pubmed	Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors.	ERBB4 UTRN	3.42e-05	11	28	2	11312300
Pubmed	Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues.	EPHA5 EPHA7	3.42e-05	11	28	2	15517401
Pubmed	Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex.	EPHA5 EPHA7	3.42e-05	11	28	2	21940705
Pubmed	Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.	ERBB4 UTRN	3.42e-05	11	28	2	12403715
Pubmed	Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors.	ERBB4 SST	3.42e-05	11	28	2	10821760
Pubmed	Competition is a driving force in topographic mapping.	EPHA5 EPHA7	3.42e-05	11	28	2	22065784
Pubmed	Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5.	EPHA5 EPHA7	3.42e-05	11	28	2	10559410
Pubmed	EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion.	EPHA5 EPHA7	4.10e-05	12	28	2	19247962
Pubmed	Transcription Factors Sp8 and Sp9 Regulate Medial Ganglionic Eminence-Derived Cortical Interneuron Migration.	ERBB4 SST	4.85e-05	13	28	2	31001083
Pubmed	Eph-ephrin A system regulates murine blastocyst attachment and spreading.	EPHA5 EPHA7	4.85e-05	13	28	2	17039519
Pubmed	EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.	EPHA5 EPHA7	4.85e-05	13	28	2	12528186
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	ERBB4 HCK ITK	5.24e-05	90	28	3	16273093
Pubmed	E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling.	SELE HCK	5.65e-05	14	28	2	20299514
Pubmed	Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.	EPHA5 EPHA7	5.65e-05	14	28	2	26941654
Pubmed	A role for the EphA family in the topographic targeting of vomeronasal axons.	EPHA5 EPHA7	5.65e-05	14	28	2	11222144
Pubmed	ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture.	ERBB4 SST	6.52e-05	15	28	2	12399441
Pubmed	Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling.	EPHA5 EPHA7	6.52e-05	15	28	2	19759535
Pubmed	The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain.	ERBB4 SST	6.52e-05	15	28	2	19332558
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	TNS1 UTRN USE1 HCK ITK EPHA7	7.26e-05	910	28	6	36736316
Pubmed	Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.	EPHA5 EPHA7	7.45e-05	16	28	2	8755474
Pubmed	Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons.	ERBB4 SST	7.45e-05	16	28	2	24142862
Pubmed	Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons.	ERBB4 SST	7.45e-05	16	28	2	20713522
Pubmed	Effects of gestational hypothyroidism on mouse brain development: Gabaergic systems and oxidative stress.	ERBB4 SST	8.44e-05	17	28	2	39048051
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHA5 EPHA7	8.44e-05	17	28	2	12217323
Pubmed	The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice.	EPHA5 EPHA7	9.49e-05	18	28	2	12421703
Pubmed	CLOCK is suggested to associate with comorbid alcohol use and depressive disorders.	ANKK1 FDFT1	9.49e-05	18	28	2	20180986
Pubmed	Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity.	EPHA5 EPHA7	9.49e-05	18	28	2	27307230
Pubmed	Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis.	ERBB4 SST	1.06e-04	19	28	2	29474907
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHA5 EPHA7	1.06e-04	19	28	2	12684176
Pubmed	Eph receptors and ephrins: effectors of morphogenesis.	EPHA5 EPHA7	1.18e-04	20	28	2	10207129
Pubmed	Multiple roles of EPH receptors and ephrins in neural development.	EPHA5 EPHA7	1.18e-04	20	28	2	11256076
Pubmed	The Eph family receptors and ligands.	EPHA5 EPHA7	1.18e-04	20	28	2	9576626
Pubmed	The ephrins and Eph receptors in neural development.	EPHA5 EPHA7	1.18e-04	20	28	2	9530499
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHA5 EPHA7	1.30e-04	21	28	2	9267020
Pubmed	Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.	ERBB4 SST	1.30e-04	21	28	2	23312517
Pubmed	Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.	ERBB4 SST	1.30e-04	21	28	2	24157949
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHA5 EPHA7	1.30e-04	21	28	2	20112066
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHA5 EPHA7	1.30e-04	21	28	2	10495276
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHA5 EPHA7	1.30e-04	21	28	2	11128993
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHA5 EPHA7	1.30e-04	21	28	2	10730216
Pubmed	Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts.	SETD2 ERBB4	1.43e-04	22	28	2	33898448
Pubmed	Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.	EPHA5 EPHA7	1.56e-04	23	28	2	25480914
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHA5 EPHA7	1.56e-04	23	28	2	19542359
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	EPHA5 EPHA7	1.71e-04	24	28	2	16446123
Pubmed	Hierarchical organization of cortical and thalamic connectivity.	ERBB4 SST	1.71e-04	24	28	2	31666704
Pubmed	The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.	ERBB4 HCK ITK	1.71e-04	134	28	3	24658140
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	HERC2 FDFT1 EPHA7	1.90e-04	139	28	3	25476789
Pubmed	Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.	HCK ITK	2.33e-04	28	28	2	18067320
Pubmed	Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.	SETD2 EPHA7	2.33e-04	28	28	2	33523829
Pubmed	Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons.	ERBB4 SST	2.33e-04	28	28	2	20392955
Pubmed	Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps.	SST EPHA7	2.33e-04	28	28	2	17698011
Pubmed	NPAS1 represses the generation of specific subtypes of cortical interneurons.	ERBB4 SST	2.50e-04	29	28	2	25467980
Pubmed	SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.	HCK ITK	3.05e-04	32	28	2	22974441
Pubmed	Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation.	EPHA5 EPHA7	3.25e-04	33	28	2	26830346
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	ERBB4 HERC2 EPHA5 EPHA7	3.41e-04	420	28	4	28065597
Pubmed	Diverse Central Projection Patterns of Retinal Ganglion Cells.	ERBB4 SST	3.66e-04	35	28	2	28228269
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	ERBB4 EPHA5	4.78e-04	40	28	2	30898150
Pubmed	Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.	EPHA5 EPHA7	5.28e-04	42	28	2	11439183
Pubmed	EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.	SETD2 BCOR	5.79e-04	44	28	2	27505670
Pubmed	Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion.	NRN1 EPHA7	6.06e-04	45	28	2	19877281
Pubmed	Malformation of the Posterior Cerebellar Vermis Is a Common Neuroanatomical Phenotype of Genetically Engineered Mice on the C57BL/6 Background.	ERBB4 SST	6.06e-04	45	28	2	29043563
Pubmed	The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas.	ERBB4 SST	6.89e-04	48	28	2	32386544
Pubmed	Regional and cell-type-specific afferent and efferent projections of the mouse claustrum.	ERBB4 SST	7.48e-04	50	28	2	36774552
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	HCK ITK	7.48e-04	50	28	2	19807924
Pubmed	Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.	EPHA5 EPHA7	7.78e-04	51	28	2	19769959
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA5 EPHA7	1.27e-04	14	22	2	1095
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	HERC2 UTRN	2.14e-04	18	22	2	91
GeneFamily	SH2 domain containing	TNS1 HCK ITK	2.41e-04	101	22	3	741
GeneFamily	Sterile alpha motif domain containing	EPHA5 EPHA7	5.08e-03	88	22	2	760
GeneFamily	Fibronectin type III domain containing	EPHA5 EPHA7	1.60e-02	160	22	2	555
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFM1 SETD2 SST CAPN11	3.02e-06	161	28	4	a7e74bc80ac11250e353e5614b19c05793fc2e95
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SELE NDUFA8 NRN1 CAPN11	7.00e-06	199	28	4	d62a2cb81b01ae59969e0b2bbe99c1c9cc96fdaa
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANKK1 SST UTRN	4.10e-05	107	28	3	fc07dd90f280191bd643398eac5c8273651d0925
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKK1 ERBB4 EPHA5	1.01e-04	145	28	3	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HFM1 SST CAPN11	1.08e-04	148	28	3	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANKK1 SST UTRN	1.28e-04	157	28	3	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HOOK2 EML5 EPHA5	1.56e-04	168	28	3	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRN1 UTRN ITK	1.65e-04	171	28	3	a8adce007ff4c713f71f2359b40cb3575b28c98d
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP3 NRN1 ITK	1.65e-04	171	28	3	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP3 NRN1 ITK	1.65e-04	171	28	3	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 UTRN ITK	1.73e-04	174	28	3	919fc124affc69acfd8f575f2c372674f3d2625e
ToppCell	368C-Endothelial_cells-Endothelial-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	SELE NRN1 EPHA7	1.76e-04	175	28	3	c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell	368C-Endothelial_cells-Endothelial-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SELE NRN1 EPHA7	1.76e-04	175	28	3	ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB4 EML5 EPHA5	1.79e-04	176	28	3	116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB4 EML5 EPHA5	1.79e-04	176	28	3	5b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB4 FDFT1 CXCL17	1.79e-04	176	28	3	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFM1 DLGAP3 SST	1.85e-04	178	28	3	1bddbc083c36657bd6910f7466126ab325e88176
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 CAPN11	1.85e-04	178	28	3	aa44851653d276226b922ee14dd1fc8d1a844cdf
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 TNS1 ITK	1.85e-04	178	28	3	0f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFM1 DLGAP3 SST	1.85e-04	178	28	3	a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 TNS1 ITK	1.85e-04	178	28	3	d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 TNS1 ITK	1.85e-04	178	28	3	b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ERBB4 HOOK2 CXCL17	1.89e-04	179	28	3	466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ERBB4 HOOK2 CXCL17	1.89e-04	179	28	3	f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 UTRN ITK	1.92e-04	180	28	3	978728c89497d26287f73974fb738ad9fde61415
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 UTRN PXDNL	1.95e-04	181	28	3	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 UTRN	1.98e-04	182	28	3	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	facs-Spleen-nan-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 UTRN ITK	1.98e-04	182	28	3	fbe5bdd642b86010dbef0a567b25c69c7335688f
ToppCell	wk_15-18-Epithelial-PNS-SST+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SST EML5 EPHA5	1.98e-04	182	28	3	a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCell	facs-Spleen-nan-18m-Lymphocytic-Cd3e_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 UTRN ITK	1.98e-04	182	28	3	da3e9093cba791c7c282eb044656046252a32789
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELE TNS1 UTRN	2.04e-04	184	28	3	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HOOK2 EML5 CXCL17	2.04e-04	184	28	3	7cc5796557379c3d1db078c1aeda40659c6e401c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HFM1 ERBB4 UTRN	2.04e-04	184	28	3	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRN1 UTRN ITK	2.04e-04	184	28	3	8c23945bafe8926f25836bc208115edd5214a2b0
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 CAPN11	2.04e-04	184	28	3	df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 CAPN11	2.04e-04	184	28	3	1ace70f12b417185bdd46042833f72b3b6815966
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC2\|Liver / Manually curated celltypes from each tissue	SLC12A3 PXDNL HCK	2.11e-04	186	28	3	92ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SST UTRN	2.11e-04	186	28	3	310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HOOK2 EML5 UTRN	2.11e-04	186	28	3	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 UTRN PXDNL	2.21e-04	189	28	3	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 UTRN	2.21e-04	189	28	3	b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SST UTRN	2.21e-04	189	28	3	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SETD2 UTRN FDFT1	2.25e-04	190	28	3	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	UTRN DISP1 EPHA7	2.25e-04	190	28	3	b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	UTRN DISP1 EPHA7	2.25e-04	190	28	3	a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SLC12A3 PXDNL	2.25e-04	190	28	3	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ERBB4 HOOK2 PXDNL	2.28e-04	191	28	3	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SST UTRN	2.28e-04	191	28	3	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SST UTRN	2.28e-04	191	28	3	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRN1 TNS1 UTRN	2.35e-04	193	28	3	bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 UTRN	2.35e-04	193	28	3	0f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ERBB4 PXDNL EPHA7	2.39e-04	194	28	3	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 UTRN	2.39e-04	194	28	3	23f2a627226aaed468c55adc42ab22e051dfe7fe
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 UTRN	2.42e-04	195	28	3	ccfb80e3bfdf5304fa798e0a47b473955ecc0c6d
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 UTRN	2.42e-04	195	28	3	f65053811074a7f2ff0368f3a63b88e2a08da1a0
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	TNS1 UTRN PXDNL	2.50e-04	197	28	3	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELE HFM1 NRN1	2.50e-04	197	28	3	a78111171819db746af7b162c77f9a324453f3ce
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE NRN1 CAPN11	2.50e-04	197	28	3	78bc83cd5546c7dd128e6791acda97f55089bc1c
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE NRN1 CAPN11	2.50e-04	197	28	3	8437c33e2c4a10a1b95343431e48d5e820b1f742
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Deep_Layer\|World / Primary Cells by Cluster	NRN1 EPHA5 EPHA7	2.50e-04	197	28	3	41e823b14697827f657b13adb3afa581bd91a9cb
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE NRN1 CAPN11	2.50e-04	197	28	3	0542badae77d2f606c13cfaf361319495c354351
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE NRN1 CAPN11	2.50e-04	197	28	3	a6a64581699cfcb9607b288976fa3b09648725b7
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DLGAP3 SLC12A3 HCK	2.54e-04	198	28	3	c64238379798ae6b292cc1914d60548c88e652de
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SELE NRN1 CAPN11	2.54e-04	198	28	3	5c82dad416938d5c460069796d808170e7dbc8d9
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SELE NRN1 CAPN11	2.54e-04	198	28	3	f7aa809040fa9f5782b92eec1f289d690eb5c7bd
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB4 FDFT1 CXCL17	2.54e-04	198	28	3	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SELE NRN1 CAPN11	2.57e-04	199	28	3	d359f3e1595ba8d8a3dc9eb2e8f2b61f3247c7a1
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ERBB4 SST EPHA5	2.57e-04	199	28	3	a255484ba77bd2741a541da278efc8cf4abbe570
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE NRN1 UTRN	2.57e-04	199	28	3	735e165580136576d39e18060550b57b8c808694
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-DBP--L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 SST UTRN	2.61e-04	200	28	3	05440294290b4f5c63342544170645a759227e00
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ERBB4 SST EPHA5	2.61e-04	200	28	3	306926cb7a847871641f02e03d52dc56fd55711c
ToppCell	Kidney\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	ERBB4 SLC12A3 TNS1	2.61e-04	200	28	3	1f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCell	distal-2-Endothelial-Vein\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELE NRN1 CAPN11	2.61e-04	200	28	3	2785225956d2422acab90e99b7debe3709cf3308
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ERBB4 SST EPHA5	2.61e-04	200	28	3	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB4 HOOK2 FDFT1	2.61e-04	200	28	3	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 SST UTRN	2.61e-04	200	28	3	d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-DBP-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 SST UTRN	2.61e-04	200	28	3	0e7a07a7c6d743d9763315c78f1bc1e1867688d8
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 SST UTRN	2.61e-04	200	28	3	862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	DLGAP3 HOOK2 EML5	2.61e-04	200	28	3	eac33be484dc443794e66e473f03e98406c2983e
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 SST UTRN	2.61e-04	200	28	3	a91345f268f13170c27309333603eb82400c9947
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-DBP\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 SST UTRN	2.61e-04	200	28	3	17ee2ca50a3690531d42dab5858c6ff9d103cae0
Drug	ponatinib	ERBB4 HCK EPHA5 EPHA7	1.41e-06	68	28	4	ctd:C545373
Drug	vandetanib	ERBB4 HCK EPHA5 EPHA7	6.36e-06	99	28	4	CID003081361
Drug	sunitinib	ERBB4 HCK EPHA5 EPHA7	1.87e-05	130	28	4	CID005329102
Drug	S-13	SST FDFT1	3.05e-05	7	28	2	CID000189036
Drug	CI-1033	ERBB4 HCK EPHA5	3.74e-05	53	28	3	CID000156413
Drug	AC1MMD6A	SELE SETD2 ITK	7.24e-05	66	28	3	CID003259138
Drug	Tetrandrine [518-34-3]; Up 200; 6.4uM; PC3; HT_HG-U133A	NRN1 TNS1 UTRN FDFT1	8.06e-05	189	28	4	5821_UP
Drug	Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; PC3; HT_HG-U133A	TNS1 UTRN POLH ITK	8.91e-05	194	28	4	3779_DN
Drug	PNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A	TNS1 UTRN ITK EPHA5	9.28e-05	196	28	4	3692_UP
Drug	Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ERBB4 SLC12A3 TNS1 UTRN	9.65e-05	198	28	4	4358_UP
Drug	Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; PC3; HT_HG-U133A	FAM53B BCOR TNS1 EPHA5	9.84e-05	199	28	4	6355_DN
Drug	Isoxicam [34552-84-6]; Down 200; 12uM; PC3; HT_HG-U133A	FAM53B SETD2 TNS1 UTRN	1.00e-04	200	28	4	7268_DN
Drug	NSC618487	SELE ERBB4 FDFT1 HCK ITK EPHA5 EPHA7	1.05e-04	933	28	7	CID000005279
Disease	Squamous cell carcinoma of lung	ANKK1 ERBB4 EPHA5	3.33e-06	32	27	3	C0149782
Disease	Embryonal Rhabdomyosarcoma	SETD2 BCOR	2.25e-05	8	27	2	C0206656
Disease	colorectal cancer (is_implicated_in)	SETD2 ERBB4 BCOR	1.83e-04	121	27	3	DOID:9256 (is_implicated_in)
Disease	breast carcinoma	DLGAP3 ERBB4 HOOK2 SLC12A3 TNS1 PXDNL	2.65e-04	1019	27	6	EFO_0000305
Disease	Cocaine Dependence	ANKK1 FAM53B FDFT1	2.75e-04	139	27	3	C0600427
Disease	Malignant neoplasm of breast	SETD2 ERBB4 HERC2 NDUFA8 TNS1 POLH	3.52e-04	1074	27	6	C0006142
Disease	intestinal cancer (implicated_via_orthology)	ERBB4 HCK	3.93e-04	32	27	2	DOID:10155 (implicated_via_orthology)
Disease	Large cell carcinoma of lung	ANKK1 EPHA5	3.93e-04	32	27	2	C0345958
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	UTRN CAPN11	4.98e-04	36	27	2	DOID:11723 (implicated_via_orthology)
Disease	personality trait	ERBB4 ITK	5.85e-04	39	27	2	EFO_0004365
Disease	Breast adenocarcinoma	ERBB4 HERC2	6.47e-04	41	27	2	C0858252
Disease	Neoplasm of uncertain or unknown behavior of breast	ERBB4 HERC2	6.47e-04	41	27	2	C0496956
Disease	metachronous colorectal adenoma	HOOK2 EPHA7	7.79e-04	45	27	2	EFO_0803377
Disease	lung adenocarcinoma (is_implicated_in)	SETD2 ERBB4	9.23e-04	49	27	2	DOID:3910 (is_implicated_in)
Disease	ghrelin measurement	SETD2 UTRN	9.23e-04	49	27	2	EFO_0600001
Disease	monocyte count	SELE HFM1 SETD2 HOOK2 FDFT1 DISP1	1.04e-03	1320	27	6	EFO_0005091
Disease	monoclonal gammopathy	HFM1 ERBB4	1.08e-03	53	27	2	EFO_0000203
Disease	interleukin 12 measurement	POLH CAPN11	1.08e-03	53	27	2	EFO_0004753
Disease	Schizophrenia	ANKK1 ERBB4 SST EML5 NRN1	1.11e-03	883	27	5	C0036341
Disease	Metastatic melanoma	ITK EPHA7	1.12e-03	54	27	2	C0278883
Disease	vascular endothelial growth factor measurement	POLH CAPN11	1.20e-03	56	27	2	EFO_0004762
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	SETD2 HCK	1.43e-03	61	27	2	C1961102
Disease	carcinoma (implicated_via_orthology)	ERBB4 HCK	1.57e-03	64	27	2	DOID:305 (implicated_via_orthology)
Disease	skin pigmentation	HERC2 SST	1.82e-03	69	27	2	EFO_0003784
Disease	Adenocarcinoma of large intestine	ERBB4 EPHA7	3.49e-03	96	27	2	C1319315

Protein segments in the cluster

Peptide	Gene	Start	Entry
CWMIDADSRPKFKEL	ERBB4	956	Q15303
VDLMKRCWDQDPKKR	ANKK1	261	Q8NFD2
MLDCWQKERNSRPKF	EPHA5	911	P54756
KLKKWMDIFRECDQD	CAPN11	641	Q9UMQ6
SEMCKFSPADWERLK	BCOR	1041	Q6W2J9
PDCWDMAARRKDQLK	DISP1	396	Q96F81
LPSWDKTERARDMKC	HERC2	2081	O95714
MKAEKWLFECRNLEE	HOOK2	381	Q96ED9
QPDWRFMESKEKDRQ	FDFT1	106	P37268
CGIMENDRWRDLDRK	FAM53B	41	Q14153
IKREKDVGMWNDERC	SELE	116	P16581
TDCQEGAKDMWDKLR	NRN1	81	Q9NPD7
DCWQKERAERPKFEQ	EPHA7	871	Q15375
MAPIKALCSQRFDDW	HFM1	336	A2PYH4
VPRKAEERWMKEDCT	PXDNL	1401	A1KZ92
MRCWKNRPEERPTFE	HCK	491	P08631
CPRDGEWFIKMLRAE	DLGAP3	791	O95886
WTNEMEGYREKRPCD	EML5	1266	Q05BV3
ECKDWFLRAPRRKFM	CXCL17	51	Q6UXB2
CDKPNKEFMLCRWEE	NDUFA8	36	P51970
KEFMLCRWEEKDPRR	NDUFA8	41	P51970
MNHCWKERPEDRPAF	ITK	591	Q08881
DRKGCFDRAMEEWRQ	UTRN	1966	P46939
RSMWADDAKKLCPDL	POLH	61	Q9Y253
RCEAMAAEKRDPDEW	USE1	16	Q9NZ43
VTFCDLDPQERKWMK	TNS1	1666	Q9HBL0
DEATVNEMRRDCPWK	SLC12A3	926	P55017
NEMRRDCPWKISDEE	SLC12A3	931	P55017
MDDFRDPQRWKECAK	SETD2	1451	Q9BYW2
MAPRERKAGCKNFFW	SST	96	P61278