Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

PTPN3 HIP1 MYH11 CTTNBP2 TRAF3IP1 CCT5 CEP290 RAB11A ITPRID2 SHROOM2 ADD3 MAPK8IP3 NIN

1.23e-0510995813GO:0008092
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

IGF1R NUCB1 NUCB2

2.64e-0443583GO:0001965
GeneOntologyMolecularFunctionactin filament binding

HIP1 MYH11 ITPRID2 SHROOM2 ADD3

5.10e-04227585GO:0051015
GeneOntologyCellularComponentcentriole

CEP162 FBF1 CEP290 RAB11A TSGA10 NIN

7.29e-06172576GO:0005814
GeneOntologyCellularComponentcentriolar satellite

CEP162 CEP290 RAB11A CCDC18 PTPN20

2.58e-05128575GO:0034451
GeneOntologyCellularComponentmicrotubule organizing center

TRAF3IP1 CCT5 CEP162 FBF1 CEP290 RAB11A CCDC18 TSGA10 TACC1 PTPN20 NIN

3.22e-059195711GO:0005815
GeneOntologyCellularComponentcentrosome

TRAF3IP1 CCT5 CEP162 FBF1 CEP290 RAB11A CCDC18 TACC1 PTPN20 NIN

3.90e-057705710GO:0005813
GeneOntologyCellularComponentsupramolecular fiber

MYH11 LMAN1 KRT75 MNS1 CCT5 CEP162 FBF1 CFAP45 RAB11A SHROOM2 PTPN20 NIN

6.53e-0511795712GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MYH11 LMAN1 KRT75 MNS1 CCT5 CEP162 FBF1 CFAP45 RAB11A SHROOM2 PTPN20 NIN

6.97e-0511875712GO:0099081
GeneOntologyCellularComponentmicrotubule

MNS1 CCT5 CEP162 CFAP45 RAB11A SHROOM2 PTPN20 NIN

9.34e-05533578GO:0005874
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT75 MNS1 CCT5 CEP162 FBF1 CFAP45 RAB11A SHROOM2 PTPN20 NIN

1.41e-048995710GO:0099513
GeneOntologyCellularComponentcell body

BPTF IGF1R RASGRF1 CCT5 TMEM132E PCLO CASP4 SHROOM2 SLC2A3 MAPK8IP3

1.85e-049295710GO:0044297
GeneOntologyCellularComponentciliary transition fiber

FBF1 NIN

3.24e-0410572GO:0097539
GeneOntologyCellularComponentsomatodendritic compartment

BPTF IGF1R CTTNBP2 RASGRF1 PCLO APBA2 CASP4 SHROOM2 SLC2A3 MAPK8IP3 NIN

4.17e-0412285711GO:0036477
GeneOntologyCellularComponentcytoplasmic region

MNS1 TRAF3IP1 CEP162 PCLO CFAP45 MAPK8IP3

4.33e-04360576GO:0099568
GeneOntologyCellularComponentcytoplasmic microtubule

MNS1 CEP162 CFAP45 NIN

4.76e-04133574GO:0005881
GeneOntologyCellularComponentaxonemal microtubule

MNS1 CEP162 CFAP45

5.61e-0459573GO:0005879
GeneOntologyCellularComponentglutamatergic synapse

HIP1 IGF1R CTTNBP2 RASGRF2 PCLO RAB11A OLFM2 SLC2A3

1.59e-03817578GO:0098978
GeneOntologyCellularComponentpostsynapse

HIP1 CELF4 IGF1R CTTNBP2 PCLO RAB11A APBA2 OLFM2 ADD3

1.63e-031018579GO:0098794
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

MNS1 TRAF3IP1 CEP162 CFAP45 MAPK8IP3

1.71e-03317575GO:0032838
GeneOntologyCellularComponentaxoneme

MNS1 TRAF3IP1 CEP162 CFAP45

2.45e-03207574GO:0005930
GeneOntologyCellularComponentciliary plasm

MNS1 TRAF3IP1 CEP162 CFAP45

2.49e-03208574GO:0097014
GeneOntologyCellularComponentcilium

MNS1 TRAF3IP1 CEP162 FBF1 CEP290 CFAP45 TSGA10 NIN

2.87e-03898578GO:0005929
GeneOntologyCellularComponentcell cortex

HIP1 CTTNBP2 PCLO SHROOM2 ADD3

3.37e-03371575GO:0005938
Domain-

PTPN3 ELMO3 RAPH1 RASGRF1 RASGRF2 APBA2 CDC42BPB

1.79e-043915772.30.29.30
DomainPH_dom-like

PTPN3 ELMO3 RAPH1 RASGRF1 RASGRF2 APBA2 CDC42BPB

3.02e-04426577IPR011993
DomainRas_G-nucl-exch_fac_CS

RASGRF1 RASGRF2

8.13e-0414572IPR019804
DomainPDZ

PTPN3 PCLO APBA2 SHROOM2

1.16e-03151574PS50106
DomainPDZ

PTPN3 PCLO APBA2 SHROOM2

1.19e-03152574IPR001478
DomainPH

ELMO3 RAPH1 RASGRF1 RASGRF2 CDC42BPB

1.57e-03278575SM00233
DomainPH_DOMAIN

ELMO3 RAPH1 RASGRF1 RASGRF2 CDC42BPB

1.59e-03279575PS50003
DomainPH_domain

ELMO3 RAPH1 RASGRF1 RASGRF2 CDC42BPB

1.62e-03280575IPR001849
DomainRasGEFN

RASGRF1 RASGRF2

1.68e-0320572SM00229
DomainRasGEF_N

RASGRF1 RASGRF2

1.85e-0321572PF00618
DomainIQ

MYH11 RASGRF1 RASGRF2

1.94e-0381573SM00015
DomainRas-like_Gua-exchang_fac_N

RASGRF1 RASGRF2

2.03e-0322572IPR000651
DomainRASGEF_NTER

RASGRF1 RASGRF2

2.03e-0322572PS50212
DomainIQ_motif_EF-hand-BS

MYH11 RASGRF1 RASGRF2

2.62e-0390573IPR000048
DomainRASGEF

RASGRF1 RASGRF2

2.84e-0326572PS00720
DomainIQ

MYH11 RASGRF1 RASGRF2

2.88e-0393573PS50096
DomainRASGEF_CAT

RASGRF1 RASGRF2

3.52e-0329572PS50009
DomainRasGEF

RASGRF1 RASGRF2

3.77e-0330572PF00617
Domain-

RASGRF1 RASGRF2

3.77e-03305721.10.840.10
DomainRas_GEF_dom

RASGRF1 RASGRF2

3.77e-0330572IPR023578
DomainRASGEF_cat_dom

RASGRF1 RASGRF2

3.77e-0330572IPR001895
DomainRasGEF

RASGRF1 RASGRF2

3.77e-0330572SM00147
DomainPH

RAPH1 RASGRF1 RASGRF2 CDC42BPB

5.23e-03229574PF00169
DomainPTPc

PTPN3 PTPN20

5.39e-0336572SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN3 PTPN20

6.31e-0339572PS50055
DomainPTPase_domain

PTPN3 PTPN20

6.95e-0341572IPR000242
DomainY_phosphatase

PTPN3 PTPN20

6.95e-0341572PF00102
PathwayREACTOME_CILIUM_ASSEMBLY

TRAF3IP1 CCT5 CEP162 FBF1 CEP290 RAB11A

3.06e-05201436M27472
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

CEP162 FBF1 CEP290 RAB11A

2.03e-0496434MM15207
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

CEP162 FBF1 CEP290 RAB11A

2.12e-0497434M27478
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

TRAF3IP1 CCT5 CEP162 FBF1 CEP290 RAB11A

2.63e-04297436M27050
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

TRAF3IP1 CEP162 FBF1 CEP290 RAB11A

4.93e-04217435MM14708
Pubmed

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

CEP162 CEP290 TACC1 NIN

4.92e-091358417920017
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PTPN3 LMAN1 RAPH1 CCT5 PRPF3 CEP162 CEP290 CCDC18 ITPRID2 CDC42BPB PTPN20 STOML2 NIN

1.42e-081049581327880917
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

BPTF MYH11 SF3B3 KRT75 RAPH1 PCLO FBF1 NUCB1 NUCB2 CFAP45 RAB11A PFKP SPEN CCDC158

7.63e-081442581435575683
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SF3B3 LMAN1 NUCB1 NUCB2 RAB11A CCDC18 TACC1 ITPRID2 PFKP CDC42BPB SNX29 ADD3 STOML2 NIN

1.11e-071487581433957083
Pubmed

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.

FBF1 CEP290 NIN

1.97e-061558324469809
Pubmed

RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors.

RASGRF1 RASGRF2

2.73e-06258226743081
Pubmed

G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs.

NUCB1 NUCB2

2.73e-06258221653697
Pubmed

Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.

RASGRF1 RASGRF2

2.73e-06258216467520
Pubmed

Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus.

RASGRF1 RASGRF2

2.73e-06258228966131
Pubmed

The environment versus genetics in controlling the contribution of MAP kinases to synaptic plasticity.

RASGRF1 RASGRF2

2.73e-06258217141611
Pubmed

The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice.

RASGRF1 RASGRF2

2.73e-06258231182637
Pubmed

Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment.

RASGRF1 RASGRF2

2.73e-06258219193896
Pubmed

Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors.

RASGRF1 RASGRF2

2.73e-06258214749369
Pubmed

A murine CDC25/ras-GRF-related protein implicated in Ras regulation.

RASGRF1 RASGRF2

2.73e-0625828293576
Pubmed

Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis.

NUCB1 NUCB2

2.73e-06258217348862
Pubmed

Modulation of nucleobindin-1 and nucleobindin-2 by caspases.

NUCB1 NUCB2

2.73e-06258218154733
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYH11 CTTNBP2 SF3B3 CCT5 PCLO PFKP SHROOM2 CDC42BPB SLC2A3 ADD3 STOML2 MAPK8IP3

3.46e-061431581237142655
Pubmed

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation.

RASGRF1 RASGRF2

8.19e-06358221685891
Pubmed

Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.

RASGRF1 RASGRF2

8.19e-06358211909944
Pubmed

Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB.

RASGRF1 RASGRF2

8.19e-06358215029245
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

MYH11 IGF1R CCT5 PCLO RAB11A PFKP SLC2A3 ADD3

8.63e-0662158822794259
Pubmed

Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.

LMAN1 NUCB1 NUCB2

8.69e-062458315308636
Pubmed

Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors.

RASGRF1 RASGRF2

1.64e-05458219692568
Pubmed

Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington's disease mice.

RAB11A SLC2A3

1.64e-05458225526803
Pubmed

CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.

CEP162 CEP290

1.64e-05458223644468
Pubmed

RasGRF Couples Nox4-Dependent Endoplasmic Reticulum Signaling to Ras.

RASGRF1 RASGRF2

1.64e-05458227856453
Pubmed

Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression.

RASGRF1 RASGRF2

1.64e-05458223145787
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

MYH11 IGF1R CCT5 PFKP CDC42BPB

1.72e-0519158533762435
Pubmed

Serological identification and expression analysis of gastric cancer-associated genes.

NUCB2 TACC1

4.08e-05658212087473
Pubmed

The somatotropic axis and longevity in mice.

IGF1R POU1F1

4.08e-05658226219867
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PTPN3 CCT5 CEP162 RAB11A TACC1 SPEN CDC42BPB ADD3

4.28e-0577758835844135
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

BPTF SF3B3 CCT5 PRPF3 CEP290 ITPRID2 PFKP SPEN STOML2

4.68e-05102458924711643
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PTPN3 IGF1R SF3B3 RASGRF2 PRPF3 CEP162 RAB11A CASP4 PFKP CDC42BPB

4.72e-051284581017353931
Pubmed

Long-term potentiation in the CA1 hippocampus induced by NR2A subunit-containing NMDA glutamate receptors is mediated by Ras-GRF2/Erk map kinase signaling.

RASGRF1 RASGRF2

5.71e-05758220661302
Pubmed

Genetic mouse models of extended lifespan.

IGF1R POU1F1

5.71e-05758214698816
Pubmed

The retardation of aging by caloric restriction: its significance in the transgenic era.

IGF1R POU1F1

5.71e-05758214698815
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

BPTF IGF1R TRAF3IP1 SPEN PTPN20 SNX29

7.13e-0542058628065597
Pubmed

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis.

CEP290 RAB11A

7.60e-05858224648492
Pubmed

Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation.

HIP1 PCLO SNX29

1.03e-045458325496667
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CCT5 PCLO APBA2 TACC1 SHROOM2 CDC42BPB ADD3 STOML2 MAPK8IP3

1.06e-04113958936417873
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

CEP162 FBF1 CEP290 NIN

1.06e-0414658421399614
Pubmed

Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.

PFKP SLC2A3

1.22e-041058218194653
Pubmed

A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.

SF3B3 PRPF3

1.49e-041158225849387
Pubmed

Accelerated failure time models provide a useful statistical framework for aging research.

IGF1R POU1F1

1.78e-041258219007875
Pubmed

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

RASGRF1 RASGRF2

2.46e-041458210373510
Pubmed

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition.

LMAN1 NUCB1 RAB11A STOML2

2.47e-0418258436225252
Pubmed

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

MNS1 INTS7 CEP290

2.52e-047358325187353
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

BPTF LMAN1 CCT5 NUCB1 NUCB2 STARD7 PFKP CDC42BPB SLC2A3

2.79e-04129758933545068
Pubmed

PDZ-Containing Proteins Targeted by the ACE2 Receptor.

PTPN3 SHROOM2

2.83e-041558234835087
Pubmed

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

RASGRF1 RASGRF2

2.83e-041558214622581
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BPTF RAPH1 ITPRID2 REST PFKP SPEN MAPK8IP3

2.95e-0477458715302935
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYH11 SF3B3 KRT75 CDC42BPB

3.67e-0420258424639526
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MYH11 SF3B3 CCT5 PCLO RAB11A PFKP STOML2

3.79e-0480758730575818
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

PTPN3 CTTNBP2 SF3B3 CCT5 INTS7 CDC42BPB

3.81e-0457358628330616
Pubmed

Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling.

SPEN STOML2

4.11e-041858219640993
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

PTPN3 RAPH1 RAB11A CDC42BPB ADD3

4.17e-0437758538117590
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PCLO ITPRID2 MAPK8IP3

4.22e-048758312465718
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

SF3B3 TRAF3IP1 CCT5 INTS7 PRPF3

4.86e-0439058517643375
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

BPTF PRPF3 PCLO POU1F1 SPEN

5.21e-0439658526687479
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SF3B3 KRT75 RAPH1 CCT5 INTS7 PRPF3 RAB11A STARD7 PFKP

5.25e-04141558928515276
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

KRT75 SYCP3 REST

5.46e-049558324029230
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PTPN3 IGF1R RAPH1 CEP162 CCDC18 ITPRID2 PFKP

5.58e-0486158736931259
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

INTS7 PRPF3 FSD2 SPEN STOML2

6.09e-0441058526949251
Pubmed

The imprinted Phlda2 gene regulates extraembryonic energy stores.

IGF1R SLC2A3

6.18e-042258219884348
Pubmed

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

MYH11 PCLO SLC2A3 ADD3

6.27e-0423358429518331
Pubmed

Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor.

SLC2A3 NIN

6.76e-042358219841136
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

CCT5 PRPF3 PCLO FBF1 CEP290 STOML2

6.76e-0463958623443559
Pubmed

The human (PEDB) and mouse (mPEDB) Prostate Expression Databases.

BPTF LMAN1 RASGRF1

7.52e-0410658311752298
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BPTF IGF1R PRPF3 NUCB2 OLFM2 SHROOM2 CDC42BPB SNX29 MAPK8IP3

7.56e-04148958928611215
Pubmed

Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse.

CEP290 NIN

8.00e-042558229487109
Pubmed

Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.

CEP162 CDC42BPB

8.00e-042558212522145
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

BPTF PRPF3 SPEN CDC42BPB

8.28e-0425158431076518
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

CCDC18 PFKP SNX29 NIN

8.28e-0425158429778605
Pubmed

Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.

IGF1R APBA2

8.66e-042658216280085
Pubmed

Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.

INTS7 PRPF3

8.66e-042658233298525
Pubmed

Identification of FBXO25-interacting proteins using an integrated proteomics approach.

MYH11 CCT5 PFKP

8.82e-0411258320473970
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

HIP1 LMAN1 CCT5 FBF1 TACC1

9.16e-0444958531732153
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

SF3B3 CCT5 PRPF3 PFKP ADD3

9.34e-0445158536168627
Pubmed

The small GTPase RSG1 controls a final step in primary cilia initiation.

CEP290 RAB11A

1.00e-032858229038301
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

PTPN3 SF3B3 CCT5 PRPF3 ITPRID2 PFKP SPEN ADD3

1.10e-03125758836526897
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

LMAN1 CEP290 RAB11A ITPRID2 SPEN

1.10e-0346858536042349
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

MYH11 SF3B3 CCT5 PRPF3 RAB11A STOML2

1.20e-0371458628302793
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TRAF3IP1 CEP290 NUCB1 APBA2 SHROOM2 CDC42BPB ADD3 MAPK8IP3

1.26e-03128558835914814
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

CTTNBP2 TACC1 REST

1.30e-0312858325332235
Pubmed

A human MAP kinase interactome.

PTPN3 MYH11 CEP290 ITPRID2 CDC42BPB

1.30e-0348658520936779
Pubmed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.

SF3B3 PRPF3

1.40e-033358228781166
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

BPTF SF3B3 CCT5 ITPRID2 PFKP

1.40e-0349458526831064
Pubmed

Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.

NUCB2 RAB11A SPEN

1.45e-0313358315604093
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

PTPN3 SHROOM2

1.48e-033458230726710
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

SF3B3 FBF1

1.48e-033458225925205
Pubmed

Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.

IGF1R SYCP3

1.48e-033458223300479
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SF3B3 LMAN1 MNS1 TRAF3IP1 PRPF3 CEP290 PFKP STOML2

1.50e-03132158827173435
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

SF3B3 RAPH1 CCT5 PRPF3 ADD3

1.55e-0350658530890647
Pubmed

De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.

MNS1 CFAP45

1.57e-033558237865089
Pubmed

SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.

MNS1 CFAP45

1.57e-033558236191189
Pubmed

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.

SF3B3 MAPK8IP3

1.57e-033558220946988
Pubmed

Binding of USP4 to cortactin enhances cell migration in HCT116 human colon cancer cells.

PRPF3 ITPRID2 PFKP

1.57e-0313758337039823
Pubmed

TXLNA enhances TBK1 phosphorylation by suppressing PPM1B recruitment.

TRAF3IP1 CCT5 PFKP

1.61e-0313858337506885
Pubmed

In-cell structural insight into the stability of sperm microtubule doublet.

MNS1 CFAP45

1.66e-033658237989994
InteractionHAUS3 interactions

SF3B3 CEP162 FBF1 CEP290 NIN

1.17e-05103585int:HAUS3
InteractionTBC1D31 interactions

MYH11 CEP162 CEP290 NIN

2.03e-0556584int:TBC1D31
InteractionVPS33B interactions

SF3B3 RAB11A CCDC18 ITPRID2 SNX29 NIN

2.27e-05199586int:VPS33B
InteractionHAUS8 interactions

CEP162 FBF1 CEP290 OLFM2 NIN

3.22e-05127585int:HAUS8
InteractionSYNE3 interactions

LMAN1 FBF1 NUCB1 NUCB2 CCDC18 TACC1 ITPRID2 NIN

3.81e-05444588int:SYNE3
InteractionH2BC9 interactions

BPTF TRAF3IP1 PCLO FBF1 CEP290 STARD7 REST CDC42BPB

3.93e-05446588int:H2BC9
InteractionIFT74 interactions

TRAF3IP1 CCT5 CEP162 FBF1 NIN

4.02e-05133585int:IFT74
InteractionNEDD1 interactions

SF3B3 CCT5 CEP162 FBF1 CEP290 NIN

4.09e-05221586int:NEDD1
InteractionTXLNA interactions

KRT75 PRPF3 CEP162 FBF1 PFKP NIN

5.89e-05236586int:TXLNA
InteractionHTT interactions

HIP1 MYH11 IGF1R CCT5 PCLO RAB11A TACC1 REST PFKP SLC2A3 ADD3

7.10e-059495811int:HTT
InteractionDTNBP1 interactions

KRT75 TRAF3IP1 CEP290 RAB11A TACC1

1.03e-04162585int:DTNBP1
InteractionMAPRE1 interactions

RAPH1 PRPF3 CEP162 CEP290 TACC1 ITPRID2 ADD3 NIN

1.06e-04514588int:MAPRE1
InteractionCEP20 interactions

CEP162 CEP290 NIN

1.16e-0433583int:CEP20
InteractionKXD1 interactions

HIP1 TRAF3IP1 TACC1 SNX29 NIN

1.29e-04170585int:KXD1
InteractionKCTD13 interactions

MYH11 CTTNBP2 SF3B3 CCT5 PCLO APBA2 PFKP SHROOM2 CDC42BPB SLC2A3 ADD3 STOML2 MAPK8IP3

1.32e-0413945813int:KCTD13
InteractionTACC1 interactions

IGF1R LMAN1 RAB11A FSD2 TACC1

1.32e-04171585int:TACC1
InteractionCSPP1 interactions

CEP162 FBF1 CEP290 NIN

1.68e-0496584int:CSPP1
InteractionTXLNG interactions

CEP162 FBF1 NUCB1 NIN

1.82e-0498584int:TXLNG
GeneFamilyPDZ domain containing

PTPN3 PCLO APBA2 SHROOM2

1.63e-041523341220
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN3 PTPN20

4.85e-0418332812
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RAPH1 RASGRF1 RASGRF2

6.18e-03206333682
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF1 RASGRF2

6.44e-0366332722
GeneFamilyEF-hand domain containing

NUCB1 NUCB2 NIN

7.32e-03219333863
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 TINAG IGF1R PCLO TSGA10 SNX29

1.94e-071935863866667dd221612589ae50f5c52f73a183a49ce6
ToppCell(11)_FOXN4+|World / shred by cell type by condition

MNS1 TRAF3IP1 CEP162 NUCB2 CFAP45 CCDC18

2.25e-07198586516b1acdf997dd8debc3dca066519366e507b414
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRF2 NUCB2 TSGA10 APBA2 SLC2A3

2.75e-06169585cc1b60eb50a274ffd72c67082c19e43af775e949
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45 CCDC18

4.87e-06190585da60bcc4b59d8e3719d8201387d567594059b1a4
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45 CCDC18

4.87e-06190585827a1f4e4ac4beada262f4fb965dd74a447a8f4f
ToppCellCaecum-T_cell-Tcm|T_cell / Region, Cell class and subclass

IGF1R NUCB2 APBA2 SLC2A3 ADD3

5.95e-06198585f889ee80c641540fd8db9eaefcd16aa51ddb2c01
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

BPTF CEP162 CEP290 CCDC18 REST

5.95e-0619858576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellmild-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IGF1R RASGRF2 NUCB2 APBA2 ADD3

6.10e-061995853e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

BPTF MNS1 CEP162 CEP290 REST

6.10e-0619958561b1ed2db71b96157b92b7535d1955a4033098da
ToppCell390C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LMAN1 NUCB2 CASP4 SLC2A3 ADD3

6.25e-06200585b6f21f5cc137eddf6ba90e81cae791b57d88d9d7
ToppCell390C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LMAN1 NUCB2 CASP4 SLC2A3 ADD3

6.25e-06200585019340e8b4b4944a49e14fdec7ce2954cbb8ba2e
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN3 HIP1 MFSD6 PFKP

4.73e-051535840ef7c45cdd854c79e527006034029767f8e108b2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NUCB2 APBA2 PLA2G4E CCDC7

5.77e-051615845fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN3 CTTNBP2 RASGRF2 SYCP3

6.49e-0516658411b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN3 CTTNBP2 RASGRF2 SYCP3

6.49e-05166584fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MNS1 CFAP45 SHROOM2 CCDC158

7.12e-05170584f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Nnat_(Neuron.Gad1Gad2.Synpr-Nnat)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PDE6C PTPN20 CCDC158

7.28e-056258336a74cfde82244ff63be07ab1e33f95ef2a84007
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Nnat_(Neuron.Gad1Gad2.Synpr-Nnat)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PDE6C PTPN20 CCDC158

7.28e-0562583c5cafb2b539974e224e570e651f43238bdd5829e
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ELMO3 PCLO SPEN CDC42BPB

8.32e-05177584946803293a7955116c80f403e99e4093e798ca3f
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

8.69e-05179584d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

CTTNBP2 KRT75 PCLO FSD2

8.69e-051795841526a130565a97c291a25a7a988089bffc1515c1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

8.69e-05179584e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYH11 TACC1 OLFM2 SHROOM2

9.07e-05181584451b87ac95154bb80018b8dd245b4a6389d81411
ToppCelldroplet-Tongue-nan-24m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MFSD6 RAB11A ITPRID2 PLA2G4E

9.47e-051835849e6c96ada930e8559246a270dfc69fb3cbb3bdf3
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRF1 RAB11A SYCP3 PTPN20

9.67e-0518458430ca56d64c961127e26122613e35aa2b46fde2df
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

MNS1 TRAF3IP1 CFAP45 CCDC18

9.87e-051855849a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell|TCGA-Uvea / Sample_Type by Project: Shred V9

HIP1 CCT5 CFAP45 PFKP

1.01e-04186584e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCellPND28-Epithelial-Epithelial_Airway|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.03e-04187584f777dd5eb5ccd554ebe1ed60a738b5dd45e18bb9
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 NUCB2 CFAP45 CCDC158

1.03e-041875847a50aded3243bef2075fb3ec550939ce0694919a
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 NUCB2 CFAP45 CCDC158

1.03e-04187584629b3e05840eb10e598b8dfaabd92ebe02f9995a
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 NUCB2 CFAP45 CCDC158

1.03e-04187584269145d71576cbe8fa217090c8aac82d915dbc04
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMAN1 NUCB1 NUCB2 PFKP

1.05e-041885847e27e49ec1eb02fb74c86ec2ccb84751bc778b21
ToppCelldroplet-Marrow-nan-21m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMAN1 NUCB1 NUCB2 PFKP

1.05e-041885844b14c3ad80507245564d5be96d33fd9361f67dd0
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

MNS1 TRAF3IP1 CEP290 CFAP45

1.05e-041885848f30535a32968a81a304315a49c0d90a77d36948
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R RASGRF2 NUCB2 APBA2

1.07e-04189584e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.07e-04189584fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R RASGRF2 NUCB2 APBA2

1.07e-041895849ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.07e-04189584565063f9e3dd79164321f8a394bd12c176baf202
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.07e-04189584497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R RASGRF2 NUCB2 APBA2

1.07e-041895845a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BPTF MYH11 ADD3 NIN

1.09e-04190584d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.09e-041905840adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPN3 PCLO RAB11A ADD3

1.09e-041905849ce301841ce9486701fa28eb2a9929e35d476878
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.09e-0419058405455775845f4ded5c27e7b83242078d23162aaf
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.12e-04191584683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.12e-04191584bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R RASGRF2 NUCB2 APBA2

1.12e-04191584696921a4f160b6b55698652488ed781e855e5e51
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.12e-041915846880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.12e-04191584a6c9df4cb4d09e0a91b3c8d7f3e091a7e95e6471
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R RASGRF2 NUCB2 APBA2

1.14e-04192584ef8970e5389bd55c1624cd6dd01a7ca7abaa8950
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.14e-04192584b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MNS1 TRAF3IP1 CEP290 CFAP45

1.14e-041925842d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R RASGRF2 NUCB2 APBA2

1.16e-0419358495f5611dd9583f339b7c9f52bb478af204fb89ad
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF4 RASGRF1 RASGRF2 PCLO

1.16e-04193584be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

RAPH1 RASGRF2 TACC1 SHROOM2

1.16e-0419358401c2df9206f1527c578e808978e58196c35e72f5
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF4 RASGRF1 RASGRF2 PCLO

1.16e-041935840c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF4 RASGRF1 RASGRF2 PCLO

1.16e-041935848689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

RAPH1 RASGRF2 TACC1 SHROOM2

1.16e-041935842531266bc57339d4e2b22a88817008e32b8c1598
ToppCellHealthy/Control-CD4+_T_naive|Healthy/Control / Disease group and Cell class

IGF1R RASGRF2 NUCB2 APBA2

1.16e-04193584f5face746df3517c86d72e31ba8f1b78c4c6b481
ToppCellHealthy/Control-CD4+_T_naive|World / Disease group and Cell class

IGF1R RASGRF2 NUCB2 APBA2

1.16e-041935846218e6cbe44d92bb98d42ef2f5e18ab7a683b100
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 TINAG PCLO SNX29

1.16e-0419358482e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellcritical-Epithelial-Ciliated-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MNS1 TRAF3IP1 NUCB2 CFAP45

1.19e-04194584176090949b53c043c58df63ad8cf4f486b350bdc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 PCLO TSGA10 SNX29

1.19e-0419458493c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 PCLO TSGA10 SNX29

1.19e-041945845eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.21e-04195584649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

PTPN3 CEP162 APBA2 ADD3

1.21e-04195584de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.21e-04195584d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MNS1 TRAF3IP1 NUCB2 CFAP45

1.21e-0419558434e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.21e-04195584129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.21e-041955843e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMAN1 MNS1 RASGRF1 PCLO

1.21e-0419558458b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIP1 MYH11 RASGRF2 SLC2A3

1.23e-041965849a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 PCLO TSGA10 SNX29

1.23e-041965846ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 PCLO TSGA10 SNX29

1.23e-04196584eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.23e-041965841386003f5d885f0ea080934f7e05fe05f142a3d5
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIP1 MYH11 RASGRF2 SLC2A3

1.23e-0419658404dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCellNS-critical-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-0419758432484fb5dde0a4525dd8028dde01ca5a4e51e4b6
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CELF4 CTTNBP2 PCLO CCDC158

1.26e-04197584ff4df77117165b6b25315e29b0722cc136eba607
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-0419758487db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcritical-Epithelial-Ciliated-diff|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-0419758434fa5568eb5e5f1ee5d4c7e5d237997eaca573ae
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-0419758491637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-critical-d_0-4-Epithelial-Ciliated-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-0419758462e20ef825b92908d7732aa625dcff7b95ef6ca8
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-0419758422c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCellNS-critical-d_16-33-Epithelial-Ciliated-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-04197584009dc732c43bfdc0d5a662b2c7d1a7a86b0d1d24
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-04197584d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MNS1 TRAF3IP1 NUCB2 CFAP45

1.26e-041975843bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIP1 MYH11 RASGRF2 SLC2A3

1.26e-04197584488e85991c5e668afb7672942726d9295b8fc7d8
ToppCell(1)_T_cell-(14)_Tcm|(1)_T_cell / shred on Cell_type and subtype

NUCB2 APBA2 SLC2A3 ADD3

1.28e-0419858440d9adb32247ab18db21a0f215b99a29b9a839b7
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HIP1 RASGRF1 TACC1 SLC2A3

1.28e-0419858485215015bb86ada0e871c413a4ecdc903a3785ca
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CELF4 CTTNBP2 PCLO OLFM2

1.28e-04198584d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HIP1 RASGRF1 TACC1 SLC2A3

1.28e-0419858438349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCell368C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NUCB1 NUCB2 SLC2A3 ADD3

1.31e-041995848766796041965a1ba40ad7abdbc244bf1418c209
ToppCellCaecum-(1)_T_cell-(14)_Tcm|Caecum / shred on region, Cell_type, and subtype

IGF1R APBA2 SLC2A3 ADD3

1.31e-041995840f89426e8dec0cbe78f6c55caaa196daf0eaf66a
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

BPTF PCLO CEP290 REST

1.31e-04199584c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellCaecum-T_cell-Tcm|Caecum / Region, Cell class and subclass

IGF1R APBA2 SLC2A3 ADD3

1.31e-04199584cab97db995a7d7df3b8f0511139ef0fe65ee55b9
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

BPTF MNS1 CEP290 REST

1.31e-04199584fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell368C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NUCB1 NUCB2 SLC2A3 ADD3

1.31e-04199584d39b40d84c72bdde756b805063317ecfad3784f8
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

BPTF ITPRID2 ADD3 NIN

1.33e-04200584dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTPN3 IGF1R PCLO MFSD6

1.33e-0420058497f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN3 IGF1R PCLO MFSD6

1.33e-04200584ecbe89ff95d046155b984c8c150e0b9e7278f839
Diseasesmoking status measurement

BPTF CELF4 IGF1R CTTNBP2 RASGRF2 NUCB2 REST CDC42BPB SNX29 ADD3

6.81e-0511605710EFO_0006527
DiseaseRenal dysplasia and retinal aplasia

TRAF3IP1 CEP290

7.65e-057572cv:C0403553
DiseaseSenior-Loken syndrome (is_implicated_in)

TRAF3IP1 CEP290

7.65e-057572DOID:0050576 (is_implicated_in)
DiseaseRenal dysplasia and retinal aplasia (disorder)

TRAF3IP1 CEP290

2.39e-0412572C0403553
Diseasevisceral heterotaxy (is_implicated_in)

MNS1 CFAP45

2.39e-0412572DOID:0050545 (is_implicated_in)
Diseasenephroblastoma (is_implicated_in)

IGF1R REST

3.29e-0414572DOID:2154 (is_implicated_in)
Diseaseneurotic disorder

CELF4 CTTNBP2 PCLO

9.96e-04101573EFO_0004257
Diseaseazoospermia (implicated_via_orthology)

SYCP3 CDC42BPB

1.25e-0327572DOID:14227 (implicated_via_orthology)
Diseaseinsomnia measurement

TRAF3IP1 RASGRF2 TMEM132E MFSD6 SNX29

1.64e-03443575EFO_0007876
DiseaseAbnormality of refraction

IGF1R TRAF3IP1 RASGRF1 PCLO ADD3 NIN

1.86e-03673576HP_0000539
Diseaseretinal degeneration (implicated_via_orthology)

PDE6C CEP290

1.86e-0333572DOID:8466 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QMIEDEQRTSMTSQK

TACC1

651

O75410
VQIEQMKQRTSSMER

CCDC7

621

Q96M83
RQDFNMMEQRKRVTQ

ADD3

46

Q9UEY8
EDKVRVMADSMQEKQ

CASP4

51

P49662
NIRMMQAQEAVSRVK

APBA2

391

Q99767
KSMTPAEREENQRMI

BPTF

2681

Q12830
VSQKQMSDRRENDMS

RAB11A

176

P62491
SSKTMMVDERQTVRQ

RAPH1

281

Q70E73
RQLMEKVQNVSQSME

OLFM2

66

O95897
RISNQMKQSMEEFRS

INTS7

666

Q9NVH2
KMRDQRAMMVQTSSQ

PTPN3

876

P26045
EMKMDTDQNTRENLT

REST

946

Q13127
VKRQDSMEALQMDRS

TRAF3IP1

471

Q8TDR0
KRDSRNMEVQVTQEM

MAPK8IP3

311

Q9UPT6
MMEVERQKSIQRQEE

CFAP45

231

Q9UL16
ERKRRDVMQVANTTM

IGF1R

736

P08069
QEEERQAQFMMRQET

PCLO

3271

Q9Y6V0
VQMTQDVQKAMDERR

PFKP

361

Q01813
ENRKDIAQEMLMNQT

PDE6C

446

P51160
RQVNEMKNSMSETVR

LMAN1

401

P49257
EVATQKVDAMRQEMR

CDC42BPB

606

Q9Y5S2
KEMMQLTRDNRASEI

MFSD6

706

Q6ZSS7
RMREHVMNEVDTNKD

NUCB2

296

P80303
MREHVMKNVDTNQDR

NUCB1

296

Q02818
IRNIMTQQKDSFEME

ITPRID2

456

P28290
AQMREQRSGMVQTKE

PTPN20

386

Q4JDL3
RMKNVRQADMLSQTD

PLA2G4E

76

Q3MJ16
EEQRKVTAQQMAMER

FBF1

841

Q8TES7
IERTQQRMKEMESVM

CCDC18

1101

Q5T9S5
NQEMRKNLEESVQEM

CEP290

236

O15078
EKRRSTEMEAQMEKQ

CTTNBP2

216

Q8WZ74
KSEAVMNQFENSMRR

CEP162

1196

Q5TB80
MNQFENSMRRVKEDT

CEP162

1201

Q5TB80
EMRATQEDFDKVMQV

ELMO3

456

Q96BJ8
EMKDESARMSQEKQV

SLC2A3

241

P11169
RNFRNKSEEMEMTTN

CCDC158

681

Q5M9N0
QIKQMMEAATRQIEE

PRPF3

141

O43395
MQQQREEDRMAKVQE

MNS1

276

Q8NEH6
DNITVQGEIMKEDRM

PLEKHA8P1

146

O95397
RQATVAMMNRKDELE

SNX29

471

Q8TEQ0
MMETQQQEIASVRKS

SYCP3

216

Q8IZU3
EMENFTSQSVKRRIM

TMEM132E

396

Q6IEE7
QMSRMKSDLRVTQQE

NIN

1781

Q8N4C6
QNKPSSQEIMRMAEE

POU1F1

236

P28069
MRKRNQIVFTMVEAE

RASGRF2

241

O14827
TRMRKVVQAEMANES

FSD2

41

A1L4K1
MTLTQIKRQEMDSQV

HIP1

971

O00291
RIERVMDNNTTVKMV

SHROOM2

1196

Q13796
IQTMTEVRARQVKEM

CCT5

471

P48643
DSMRKRNQVVFSMLE

RASGRF1

236

Q13972
DTDKERTMRRMQQMA

CELF4

231

Q9BZC1
NMEAMSDRVRKATQQ

MYH11

1751

P35749
SRRKQQMEMEIAKSE

SPEN

1176

Q96T58
VKESMQMQVEAERRK

STOML2

186

Q9UJZ1
TKAQRKQQMAEEMVE

SF3B3

811

Q15393
NILKSEESENRQMME

TSGA10

401

Q9BZW7
EESENRQMMEQLRKA

TSGA10

406

Q9BZW7
QRSINEMKRLEEMSN

STARD7

96

Q9NQZ5
RVSSNETEIMKEIMQ

TINAG

356

Q9UJW2
RNTKQEISEMNRMIQ

KRT75

361

O95678