Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	high-affinity IgG receptor activity	FCGR1A FCGR1BP	1.28e-05	2	72	2	GO:0019771
GeneOntologyMolecularFunction	leukotriene receptor binding	FCGR1A FCGR1BP	1.28e-05	2	72	2	GO:0031774
GeneOntologyMolecularFunction	extracellular matrix constituent, lubricant activity	MUC17 MUC3A	7.66e-05	4	72	2	GO:0030197
GeneOntologyMolecularFunction	IgG receptor activity	FCGR1A FCGR1BP	2.66e-04	7	72	2	GO:0019770
GeneOntologyMolecularFunction	structural molecule activity	NEFM VIM NEFL POM121 MUC17 VCAN LAD1 PLEC RIMS2 POM121C MUC3A	3.28e-04	891	72	11	GO:0005198
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1A KMT2C	3.54e-04	8	72	2	GO:0140945
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETD1A KMT2C SETD2	5.35e-04	44	72	3	GO:0140938
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1A KMT2C	5.66e-04	10	72	2	GO:0140999
GeneOntologyMolecularFunction	kinase binding	VIM CACNB1 HIF1A TPCN2 DSCAM TIAM1 SKAP1 BARD1 SORBS1 SMCR8 CASK	6.64e-04	969	72	11	GO:0019900
GeneOntologyMolecularFunction	IgG binding	FCGR1A FCGR1BP	6.91e-04	11	72	2	GO:0019864
GeneOntologyMolecularFunction	transcription coactivator binding	FOXO1 ZBTB49 HIF1A	9.77e-04	54	72	3	GO:0001223
GeneOntologyMolecularFunction	protein kinase binding	VIM CACNB1 HIF1A TPCN2 DSCAM TIAM1 SKAP1 SORBS1 SMCR8 CASK	1.11e-03	873	72	10	GO:0019901
GeneOntologyMolecularFunction	immunoglobulin receptor activity	FCGR1A FCGR1BP	1.13e-03	14	72	2	GO:0019763
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	NEFM VIM NEFL PLEC	1.25e-03	130	72	4	GO:0005200
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	SETD1A KMT2C SETD2	1.90e-03	68	72	3	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	SETD1A KMT2C SETD2	1.99e-03	69	72	3	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1A KMT2C SETD2	2.16e-03	71	72	3	GO:0042054
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1A KMT2C	2.34e-03	20	72	2	GO:0042800
GeneOntologyBiologicalProcess	neurofilament bundle assembly	NEFM NEFL	3.70e-05	3	73	2	GO:0033693
GeneOntologyBiologicalProcess	regulation of axonogenesis	NEFM VIM NEFL SEMA6D DSCAM TIAM1	6.10e-05	192	73	6	GO:0050770
GeneOntologyBiologicalProcess	cell morphogenesis	TANC2 NEFM VIM CCDC88C NEFL SEMA6D CELSR3 DSCAM TIAM1 PLEC RIMS2 MUC3A JMJD1C CASK	6.54e-05	1194	73	14	GO:0000902
GeneOntologyBiologicalProcess	cell recognition	CELSR3 FCGR1A DSCAM FCGR1BP UBAP2L VCAN	7.24e-05	198	73	6	GO:0008037
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	NEFL HIF1A FCGR1A DSCAM FCGR1BP TIAM1 UBAP2L ARHGEF5 SKAP1 RIMS2 IL1RAP SMCR8 BAIAP2L2 C2CD5 CASK	7.26e-05	1366	73	15	GO:0051130
GeneOntologyBiologicalProcess	intermediate filament polymerization or depolymerization	NEFM NEFL	7.38e-05	4	73	2	GO:0045105
GeneOntologyBiologicalProcess	positive regulation of nervous system development	VIM NEFL HIF1A DSCAM TIAM1 VCAN IL1RAP CASK	1.13e-04	418	73	8	GO:0051962
GeneOntologyBiologicalProcess	type III hypersensitivity	FCGR1A FCGR1BP	1.23e-04	5	73	2	GO:0001802
GeneOntologyBiologicalProcess	regulation of type III hypersensitivity	FCGR1A FCGR1BP	1.23e-04	5	73	2	GO:0001803
GeneOntologyBiologicalProcess	positive regulation of type III hypersensitivity	FCGR1A FCGR1BP	1.23e-04	5	73	2	GO:0001805
GeneOntologyBiologicalProcess	intermediate filament organization	NEFM VIM NEFL PLEC	1.45e-04	75	73	4	GO:0045109
GeneOntologyBiologicalProcess	cell projection morphogenesis	TANC2 NEFM VIM NEFL SEMA6D CELSR3 DSCAM TIAM1 RIMS2 MUC3A CASK	1.46e-04	826	73	11	GO:0048858
GeneOntologyBiologicalProcess	hemidesmosome assembly	PLEC ITGB4	1.84e-04	6	73	2	GO:0031581
GeneOntologyBiologicalProcess	regulation of axon diameter	NEFM NEFL	1.84e-04	6	73	2	GO:0031133
GeneOntologyBiologicalProcess	positive regulation of neurogenesis	VIM NEFL HIF1A DSCAM TIAM1 VCAN CASK	2.55e-04	354	73	7	GO:0050769
GeneOntologyBiologicalProcess	positive regulation of stress granule assembly	HIF1A UBAP2L	3.41e-04	8	73	2	GO:0062029
GeneOntologyBiologicalProcess	intermediate filament bundle assembly	NEFM NEFL	3.41e-04	8	73	2	GO:0045110
GeneOntologyBiologicalProcess	regulation of nervous system development	VIM NEFL HIF1A SEMA6D DSCAM TIAM1 VCAN IL1RAP CASK	3.50e-04	625	73	9	GO:0051960
GeneOntologyBiologicalProcess	positive regulation of autophagy	FOXO1 ATF6 SETD2 HIF1A SMCR8	3.71e-04	173	73	5	GO:0010508
GeneOntologyBiologicalProcess	regulation of protein localization	FOXO1 SETD2 HIF1A CELSR3 TIAM1 ARHGEF5 BARD1 SORBS1 WRAP53 WNK3 C2CD5 CASK	4.04e-04	1087	73	12	GO:0032880
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	NEFM VIM NEFL PLEC	4.22e-04	99	73	4	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	NEFM VIM NEFL PLEC	4.38e-04	100	73	4	GO:0045103
GeneOntologyBiologicalProcess	regulation of neurogenesis	VIM NEFL HIF1A SEMA6D DSCAM TIAM1 VCAN CASK	4.63e-04	515	73	8	GO:0050767
GeneOntologyBiologicalProcess	neuron projection morphogenesis	TANC2 NEFM VIM NEFL SEMA6D CELSR3 DSCAM TIAM1 RIMS2 CASK	5.06e-04	802	73	10	GO:0048812
GeneOntologyBiologicalProcess	positive regulation of type IIa hypersensitivity	FCGR1A FCGR1BP	5.46e-04	10	73	2	GO:0001798
GeneOntologyBiologicalProcess	positive regulation of type II hypersensitivity	FCGR1A FCGR1BP	5.46e-04	10	73	2	GO:0002894
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	TANC2 NEFM VIM NEFL SEMA6D CELSR3 DSCAM TIAM1 RIMS2 CASK	5.95e-04	819	73	10	GO:0120039
GeneOntologyBiologicalProcess	cell junction organization	TANC2 NEFL CACNB1 DSCAM TIAM1 SORBS1 PLEC RIMS2 IL1RAP ITGB4 CASK	5.98e-04	974	73	11	GO:0034330
GeneOntologyBiologicalProcess	regulation of type IIa hypersensitivity	FCGR1A FCGR1BP	6.66e-04	11	73	2	GO:0001796
GeneOntologyBiologicalProcess	regulation of type II hypersensitivity	FCGR1A FCGR1BP	6.66e-04	11	73	2	GO:0002892
GeneOntologyBiologicalProcess	neurofilament cytoskeleton organization	NEFM NEFL	6.66e-04	11	73	2	GO:0060052
GeneOntologyBiologicalProcess	synapse organization	TANC2 NEFL CACNB1 DSCAM TIAM1 SORBS1 RIMS2 IL1RAP CASK	6.79e-04	685	73	9	GO:0050808
GeneOntologyCellularComponent	anchoring junction	FOCAD VIM CCDC88C TIAM1 ARHGEF5 SKAP1 NHS SORBS1 PLEC ITGB4 PDLIM2 FRMD4B BAIAP2L2 WNK3 CASK	1.35e-06	976	74	15	GO:0070161
GeneOntologyCellularComponent	presynaptic cytoskeleton	NEFM NEFL RIMS2	1.51e-05	14	74	3	GO:0099569
GeneOntologyCellularComponent	presynaptic intermediate filament cytoskeleton	NEFM NEFL	3.70e-05	3	74	2	GO:0099182
GeneOntologyCellularComponent	Golgi lumen	MUC17 VCAN MUC16 MUC12 MUC3A	4.25e-05	109	74	5	GO:0005796
GeneOntologyCellularComponent	cell-cell junction	CCDC88C TIAM1 SKAP1 NHS SORBS1 PDLIM2 FRMD4B BAIAP2L2 WNK3 CASK	4.27e-05	591	74	10	GO:0005911
GeneOntologyCellularComponent	postsynaptic intermediate filament cytoskeleton	NEFM NEFL	7.38e-05	4	74	2	GO:0099160
GeneOntologyCellularComponent	apical junction complex	CCDC88C NHS SORBS1 FRMD4B WNK3	2.45e-04	158	74	5	GO:0043296
GeneOntologyCellularComponent	hemidesmosome	PLEC ITGB4	6.66e-04	11	74	2	GO:0030056
GeneOntologyCellularComponent	focal adhesion	FOCAD VIM NHS SORBS1 PLEC ITGB4 CASK	8.27e-04	431	74	7	GO:0005925
GeneOntologyCellularComponent	cell-substrate junction	FOCAD VIM NHS SORBS1 PLEC ITGB4 CASK	9.70e-04	443	74	7	GO:0030055
GeneOntologyCellularComponent	neurofilament	NEFM NEFL	1.09e-03	14	74	2	GO:0005883
Domain	SEA	MUC17 MUC16 MUC12 MUC3A	1.70e-06	23	72	4	PS50024
Domain	SEA_dom	MUC17 MUC16 MUC12 MUC3A	1.70e-06	23	72	4	IPR000082
Domain	Filament_head	NEFM VIM NEFL	1.90e-06	7	72	3	PF04732
Domain	Intermed_filament_DNA-bd	NEFM VIM NEFL	1.90e-06	7	72	3	IPR006821
Domain	SEA	MUC17 MUC16 MUC3A	1.94e-05	14	72	3	SM00200
Domain	Post-SET_dom	SETD1A KMT2C SETD2	2.97e-05	16	72	3	IPR003616
Domain	PostSET	SETD1A KMT2C SETD2	2.97e-05	16	72	3	SM00508
Domain	POST_SET	SETD1A KMT2C SETD2	2.97e-05	16	72	3	PS50868
Domain	SEA	MUC17 MUC16 MUC12	8.03e-05	22	72	3	PF01390
Domain	SH3	CACNB1 ARHGEF5 SKAP1 SORBS1 BAIAP2L2 CASK	1.85e-04	216	72	6	SM00326
Domain	SH3	CACNB1 ARHGEF5 SKAP1 SORBS1 BAIAP2L2 CASK	1.85e-04	216	72	6	PS50002
Domain	SH3_domain	CACNB1 ARHGEF5 SKAP1 SORBS1 BAIAP2L2 CASK	2.04e-04	220	72	6	IPR001452
Domain	SH3_2	ARHGEF5 SORBS1 BAIAP2L2 CASK	3.40e-04	86	72	4	IPR011511
Domain	SH3_2	ARHGEF5 SORBS1 BAIAP2L2 CASK	3.40e-04	86	72	4	PF07653
Domain	EGF_1	CELSR3 MUC17 VCAN MUC12 MUC3A ITGB4	4.49e-04	255	72	6	PS00022
Domain	EGF-like_CS	CELSR3 MUC17 VCAN MUC12 MUC3A ITGB4	5.08e-04	261	72	6	IPR013032
Domain	SET	SETD1A KMT2C SETD2	5.27e-04	41	72	3	PF00856
Domain	EGF_2	CELSR3 MUC17 VCAN MUC12 MUC3A ITGB4	5.50e-04	265	72	6	PS01186
Domain	SET	SETD1A KMT2C SETD2	7.40e-04	46	72	3	SM00317
Domain	SET_dom	SETD1A KMT2C SETD2	9.45e-04	50	72	3	IPR001214
Domain	SET	SETD1A KMT2C SETD2	9.45e-04	50	72	3	PS50280
Domain	-	EBF2 STBD1 FCGR1A DSCAM FCGR1BP VCAN LRRN4 IL1RAP ITGB4	9.80e-04	663	72	9	2.60.40.10
Domain	-	MUC17 MUC16	1.49e-03	15	72	2	3.30.70.960
Domain	Ig-like_fold	EBF2 STBD1 FCGR1A DSCAM FCGR1BP VCAN LRRN4 IL1RAP ITGB4	1.52e-03	706	72	9	IPR013783
Domain	Intermediate_filament_CS	NEFM VIM NEFL	1.85e-03	63	72	3	IPR018039
Domain	PDZ	TIAM1 RIMS2 PDLIM2 CASK	2.15e-03	141	72	4	PF00595
Domain	PDZ	TIAM1 RIMS2 PDLIM2 CASK	2.57e-03	148	72	4	SM00228
Domain	Filament	NEFM VIM NEFL	2.60e-03	71	72	3	SM01391
Domain	-	TIAM1 RIMS2 PDLIM2 CASK	2.69e-03	150	72	4	2.30.42.10
Domain	IF	NEFM VIM NEFL	2.71e-03	72	72	3	PS00226
Domain	PDZ	TIAM1 RIMS2 PDLIM2 CASK	2.76e-03	151	72	4	PS50106
Domain	Filament	NEFM VIM NEFL	2.82e-03	73	72	3	PF00038
Domain	PDZ	TIAM1 RIMS2 PDLIM2 CASK	2.82e-03	152	72	4	IPR001478
Domain	IF	NEFM VIM NEFL	3.16e-03	76	72	3	IPR001664
Domain	SH3_9	ARHGEF5 SORBS1 BAIAP2L2	3.40e-03	78	72	3	PF14604
Domain	SH3_1	CACNB1 ARHGEF5 SKAP1 SORBS1	3.71e-03	164	72	4	PF00018
Domain	Guanylate_kin	CACNB1 CASK	4.49e-03	26	72	2	PF00625
Domain	GK/Ca_channel_bsu	CACNB1 CASK	4.49e-03	26	72	2	IPR008145
Domain	Guanylate_kin-like_dom	CACNB1 CASK	4.49e-03	26	72	2	IPR008144
Domain	GuKc	CACNB1 CASK	4.49e-03	26	72	2	SM00072
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC17 MUC16 MUC12 MUC3A	4.52e-07	16	58	4	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC17 MUC16 MUC12 MUC3A	5.90e-07	17	58	4	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC17 MUC16 MUC12 MUC3A	2.15e-06	23	58	4	M556
Pathway	REACTOME_DECTIN_2_FAMILY	MUC17 MUC16 MUC12 MUC3A	3.60e-06	26	58	4	M27483
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC17 MUC16 MUC12 MUC3A	1.20e-04	62	58	4	M546
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	MUC17 MUC16 MUC12 MUC3A	1.73e-04	68	58	4	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	MUC17 VCAN MUC16 MUC12 MUC3A	2.98e-04	143	58	5	M27275
Pubmed	Expression of NF-L and NF-M in fibroblasts reveals coassembly of neurofilament and vimentin subunits.	NEFM VIM NEFL	9.25e-09	3	74	3	2493000
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 FOXO1 VIM CCDC88C TIAM1 PHF3 ARHGEF5 RBM7 NHS SORBS1 PLEC CFAP97 WNK3	3.12e-08	861	74	13	36931259
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	TANC2 NEFM NEFL CACNB1 TIAM1 BCLAF1 SORBS1 RIMS2	3.47e-08	231	74	8	16452087
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC17 MUC16 MUC12 MUC3A	5.65e-08	18	74	4	18834073
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FOCAD NEFM VIM NEFL ZSWIM8 ATF6 CELSR3 FCGR1A DSCAM TIAM1 SORBS1 PLEC WRAP53 FRMD4B CASK	7.09e-08	1285	74	15	35914814
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TANC2 NEFM VIM CCDC88C NEFL CACNB1 DSCAM UBAP2L BCLAF1 SORBS1 UBN2 WNK3 CASK	1.14e-07	963	74	13	28671696
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	NEFM VIM NEFL SETD2 CELSR3 BCLAF1 PLEC	1.54e-07	187	74	7	26460568
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NEFM VIM SETD1A KMT2C SETD2 UBAP2L PHF3 BCLAF1 UBN2 JMJD1C	2.57e-07	549	74	10	38280479
Pubmed	Defining the lineage of thermogenic perivascular adipose tissue.	EBF2 FCGR1A FCGR1BP GLI1	4.31e-07	29	74	4	33846639
Pubmed	Genomic organization of the region spanning D14Mit262 and D14Mit86 on mouse chromosome 14 and exclusion of Adam28 and Adamdec1 as the cataract-causing gene, lr2.	EBF2 NEFM NEFL	5.14e-07	8	74	3	17268172
Pubmed	Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system.	NEFM VIM NEFL	7.70e-07	9	74	3	7720210
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	TANC2 NEFM CACNB1 UBAP2L SORBS1 PLEC RIMS2 C2CD5	7.70e-07	347	74	8	17114649
Pubmed	A human MAP kinase interactome.	KMT2C ATF6 POM121 KIAA1328 SORBS1 MUC12 PLEC POM121C ITGB4	9.33e-07	486	74	9	20936779
Pubmed	A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.	CACNB1 SRRM4 SORBS1 RIMS2 CASK	1.09e-06	85	74	5	23055939
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	VIM SETD2 UBAP2L BCLAF1 KCMF1 LAD1 PLEC PDLIM2 CASK	1.24e-06	503	74	9	36217030
Pubmed	Stage-specific expression of alkaline phosphatase during neural development in the mouse.	NEFM VIM NEFL	1.51e-06	11	74	3	7533563
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A KMT2C CELSR3 BCLAF1 SRRM4 RIMS2 FRMD4B GRAMD4 CFAP97	1.87e-06	529	74	9	14621295
Pubmed	Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome.	NEFM FCGR1A FCGR1BP GLI1	3.14e-06	47	74	4	24357327
Pubmed	O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.	NEFM NEFL SORBS1	3.31e-06	14	74	3	16452088
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	PHF3 BCLAF1 UBN2	3.31e-06	14	74	3	28263302
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FOCAD TANC2 CCDC88C SETD1A KMT2C CELSR3 GLI1 LAD1 PLEC WRAP53 POM121C ITGB4	3.56e-06	1105	74	12	35748872
Pubmed	Plectin deficiency affects precursor formation and dynamics of vimentin networks.	VIM PLEC	4.47e-06	2	74	2	18848541
Pubmed	Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.	FCGR1A FCGR1BP	4.47e-06	2	74	2	28814603
Pubmed	Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan.	FCGR1A FCGR1BP	4.47e-06	2	74	2	37733444
Pubmed	Expression of MUC17 is regulated by HIF1α-mediated hypoxic responses and requires a methylation-free hypoxia responsible element in pancreatic cancer.	HIF1A MUC17	4.47e-06	2	74	2	22970168
Pubmed	Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein.	NEFM NEFL	4.47e-06	2	74	2	3036526
Pubmed	Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.	FCGR1A FCGR1BP	4.47e-06	2	74	2	9257847
Pubmed	Epidermolysis bullosa with congenital pyloric atresia: novel mutations in the beta 4 integrin gene (ITGB4) and genotype/phenotype correlations.	PLEC ITGB4	4.47e-06	2	74	2	11328943
Pubmed	Bclaf1 is a direct target of HIF-1 and critically regulates the stability of HIF-1α under hypoxia.	HIF1A BCLAF1	4.47e-06	2	74	2	32029898
Pubmed	Tumor promoting effect of PDLIM2 downregulation involves mitochondrial ROS, oncometabolite accumulations and HIF-1α activation.	HIF1A PDLIM2	4.47e-06	2	74	2	38880883
Pubmed	Fully functional, naturally occurring and C-terminally truncated variant human immunodeficiency virus (HIV) Vif does not bind to HIV Gag but influences intermediate filament structure.	VIM PLEC	4.47e-06	2	74	2	11172097
Pubmed	The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.	FCGR1A FCGR1BP	4.47e-06	2	74	2	25231998
Pubmed	Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.	FCGR1A FCGR1BP	4.47e-06	2	74	2	30190171
Pubmed	Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.	FCGR1A FCGR1BP	4.47e-06	2	74	2	2136886
Pubmed	FcRγ deficiency improves survival in experimental sepsis by down-regulating TLR4 signaling pathway.	FCGR1A FCGR1BP	4.47e-06	2	74	2	30552619
Pubmed	Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice.	FCGR1A FCGR1BP	4.47e-06	2	74	2	35833115
Pubmed	Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain.	FCGR1A FCGR1BP	4.47e-06	2	74	2	15528358
Pubmed	Oxidation and nitrosylation of cysteines proximal to the intermediate filament (IF)-binding site of plectin: effects on structure and vimentin binding and involvement in IF collapse.	VIM PLEC	4.47e-06	2	74	2	17224453
Pubmed	HIF-1-mediated expression of Foxo1 serves an important role in the proliferation and apoptosis of osteoblasts derived from children's iliac cancellous bone.	FOXO1 HIF1A	4.47e-06	2	74	2	29512721
Pubmed	Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.	FCGR1A FCGR1BP	4.47e-06	2	74	2	14991835
Pubmed	Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.	FCGR1A FCGR1BP	4.47e-06	2	74	2	1402657
Pubmed	Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.	PLEC ITGB4	4.47e-06	2	74	2	15817481
Pubmed	Epigenotype-genotype-phenotype correlations in SETD1A and SETD2 chromatin disorders.	SETD1A SETD2	4.47e-06	2	74	2	37166351
Pubmed	Actin-binding domain of mouse plectin. Crystal structure and binding to vimentin.	VIM PLEC	4.47e-06	2	74	2	15128297
Pubmed	Mouse FcgammaRI: identification and functional characterization of five new alleles.	FCGR1A FCGR1BP	4.47e-06	2	74	2	10752630
Pubmed	Neuronal FcγRI mediates acute and chronic joint pain.	FCGR1A FCGR1BP	4.47e-06	2	74	2	31211699
Pubmed	Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex.	FCGR1A FCGR1BP	4.47e-06	2	74	2	16849450
Pubmed	BARD1 Autoantibody Blood Test for Early Detection of Ovarian Cancer.	BARD1 MUC16	4.47e-06	2	74	2	34201956
Pubmed	CD64 plays a key role in diabetic wound healing.	FCGR1A FCGR1BP	4.47e-06	2	74	2	38524127
Pubmed	Developmentally ordered appearance of a functional Fc gamma receptor on TCR V gamma 3 thymocytes. Evidence for stimulation-induced expression.	FCGR1A FCGR1BP	4.47e-06	2	74	2	8077658
Pubmed	Modulating IgG effector function by Fc glycan engineering.	FCGR1A FCGR1BP	4.47e-06	2	74	2	28289219
Pubmed	Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice.	FCGR1A FCGR1BP	4.47e-06	2	74	2	35273604
Pubmed	IgG3-mediated enhancement of the antibody response is normal in Fc gammaRI-deficient mice.	FCGR1A FCGR1BP	4.47e-06	2	74	2	16305642
Pubmed	Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.	FCGR1A FCGR1BP	4.47e-06	2	74	2	21124939
Pubmed	Macrophages eliminate circulating tumor cells after monoclonal antibody therapy.	FCGR1A FCGR1BP	4.47e-06	2	74	2	24430180
Pubmed	Regulation of the association of alpha 6 beta 4 with vimentin intermediate filaments in endothelial cells.	VIM ITGB4	4.47e-06	2	74	2	12441134
Pubmed	Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity.	FCGR1A FCGR1BP	4.47e-06	2	74	2	38885133
Pubmed	Novel Fc gamma receptor I family gene products in human mononuclear cells.	FCGR1A FCGR1BP	4.47e-06	2	74	2	1430234
Pubmed	The FcRgamma chain is not essential for induction of experimental allergic encephalomyelitis (EAE) or anti-myelin antibody-mediated exacerbation of EAE.	FCGR1A FCGR1BP	4.47e-06	2	74	2	15835266
Pubmed	Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.	FCGR1A FCGR1BP	4.47e-06	2	74	2	8663283
Pubmed	Widespread aplasia cutis congenita in sibs with PLEC1 and ITGB4 variants.	PLEC ITGB4	4.47e-06	2	74	2	31184804
Pubmed	Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene.	FCGR1A FCGR1BP	4.47e-06	2	74	2	1830050
Pubmed	Histone methyltransferase SETD1A interacts with HIF1α to enhance glycolysis and promote cancer progression in gastric cancer.	SETD1A HIF1A	4.47e-06	2	74	2	32291851
Pubmed	Functional characteristics of the high affinity IgG receptor, FcγRI.	FCGR1A FCGR1BP	4.47e-06	2	74	2	21325219
Pubmed	FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo.	FCGR1A FCGR1BP	4.47e-06	2	74	2	8611682
Pubmed	Keeping the vimentin network under control: cell-matrix adhesion-associated plectin 1f affects cell shape and polarity of fibroblasts.	VIM PLEC	4.47e-06	2	74	2	20702585
Pubmed	Direct targeting of genetically modified tumour cells to Fc gammaRI triggers potent tumour cytotoxicity.	FCGR1A FCGR1BP	4.47e-06	2	74	2	16409296
Pubmed	Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content.	NEFM NEFL	4.47e-06	2	74	2	9566972
Pubmed	[Detection of level and mutation of neurofilament mRNA in Alzheimer's disease].	NEFM NEFL	4.47e-06	2	74	2	12133495
Pubmed	Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.	FCGR1A FCGR1BP	4.47e-06	2	74	2	30744065
Pubmed	Serum anti-Fcgamma receptor autoantibodies in patients with alopecia areata.	FCGR1A FCGR1BP	4.47e-06	2	74	2	17124586
Pubmed	Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice.	FCGR1A FCGR1BP	4.47e-06	2	74	2	8480181
Pubmed	Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.	FCGR1A FCGR1BP	4.47e-06	2	74	2	29576375
Pubmed	Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.	FCGR1A FCGR1BP	4.47e-06	2	74	2	18245810
Pubmed	Biochemical characterization of murine Fc gamma RI.	FCGR1A FCGR1BP	4.47e-06	2	74	2	8478020
Pubmed	FcγR-binding affinity of monoclonal murine IgG1s carrying different N-linked Fc oligosaccharides.	FCGR1A FCGR1BP	4.47e-06	2	74	2	31554601
Pubmed	Variable metastatic potentials correlate with differential plectin and vimentin expression in syngeneic androgen independent prostate cancer cells.	VIM PLEC	4.47e-06	2	74	2	23717685
Pubmed	Vimentin-mediated regulation of cell motility through modulation of beta4 integrin protein levels in oral tumor derived cells.	VIM ITGB4	4.47e-06	2	74	2	26646105
Pubmed	The involvement of FcR mechanisms in antibody-mediated rejection.	FCGR1A FCGR1BP	4.47e-06	2	74	2	18049118
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD1A SETD2 POM121 UBAP2L PHF3 BCLAF1 POM121C C2CD5	4.47e-06	440	74	8	34244565
Pubmed	Regulation of ubiquitin-proteasome system-mediated Tip110 protein degradation by USP15.	NEFM HIF1A BCLAF1	5.08e-06	16	74	3	24984263
Pubmed	Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina.	NEFM VIM GLI1	6.15e-06	17	74	3	15797020
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	DSCAM PHF3 UBN2	7.37e-06	18	74	3	25363768
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	TANC2 NEFM SRRM4 SORBS1 RIMS2	8.20e-06	128	74	5	30995482
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 CCDC88C SETD2 POM121 UBN2 POM121C JMJD1C C2CD5	1.02e-05	493	74	8	15368895
Pubmed	Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.	FCGR1A FCGR1BP	1.34e-05	3	74	2	16841095
Pubmed	Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1.	NEFM NEFL	1.34e-05	3	74	2	11050249
Pubmed	Sequence and structure of the mouse gene coding for the largest neurofilament subunit.	NEFM NEFL	1.34e-05	3	74	2	3220257
Pubmed	Neurofilament homeostasis and motoneurone degeneration.	NEFM NEFL	1.34e-05	3	74	2	11135306
Pubmed	Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits.	NEFM NEFL	1.34e-05	3	74	2	7790359
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121 POM121C	1.34e-05	3	74	2	30802453
Pubmed	Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.	FCGR1A FCGR1BP	1.34e-05	3	74	2	22003208
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121 POM121C	1.34e-05	3	74	2	35507432
Pubmed	Unique monoclonal antibodies define expression of Fc gamma RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells.	FCGR1A FCGR1BP	1.34e-05	3	74	2	12594281
Pubmed	Development of proteoglycan-induced arthritis is critically dependent on Fcgamma receptor type III expression.	FCGR1A FCGR1BP	1.34e-05	3	74	2	15880819
Pubmed	Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.	MUC16 MUC12	1.34e-05	3	74	2	26770020
Pubmed	Neurofilaments and motor neuron disease.	NEFM NEFL	1.34e-05	3	74	2	17708953
Pubmed	A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies.	FCGR1A FCGR1BP	1.34e-05	3	74	2	28924242
Pubmed	Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.	MUC17 MUC3A	1.34e-05	3	74	2	10512748
Pubmed	Glycosylation of mammalian neurofilaments. Localization of multiple O-linked N-acetylglucosamine moieties on neurofilament polypeptides L and M.	NEFM NEFL	1.34e-05	3	74	2	8344946
Interaction	SFN interactions	TANC2 FOXO1 VIM CCDC88C SETD1A HIF1A TIAM1 PHF3 ARHGEF5 LAD1 RBM7 NHS SORBS1 PLEC	1.88e-07	692	74	14	int:SFN
Interaction	SIRT6 interactions	VIM SETD1A SETD2 HIF1A POM121 CELSR3 UBAP2L PHF3 BCLAF1 POM121C C2CD5	1.73e-05	628	74	11	int:SIRT6
Interaction	GFAP interactions	FOXO1 NEFM VIM NEFL POM121 DSCAM UNC13D	2.55e-05	236	74	7	int:GFAP
Interaction	NEFL interactions	FOXO1 NEFM VIM NEFL DSCAM SKAP1	2.80e-05	161	74	6	int:NEFL
Interaction	YAP1 interactions	FOXO1 NEFM VIM SETD1A KMT2C SETD2 HIF1A UBAP2L PHF3 BCLAF1 GLI1 PLEC UBN2 JMJD1C	3.85e-05	1095	74	14	int:YAP1
Interaction	GAN interactions	NEFM VIM NEFL SETD2 CELSR3 BCLAF1 PLEC	3.98e-05	253	74	7	int:GAN
Interaction	YWHAH interactions	TANC2 FOXO1 VIM CCDC88C TIAM1 PHF3 ARHGEF5 RBM7 NHS SORBS1 PLEC RIMS2 CFAP97 WNK3	4.13e-05	1102	74	14	int:YWHAH
Interaction	YWHAE interactions	TANC2 FOXO1 VIM CCDC88C CACNB1 MAGEB4 STBD1 TIAM1 ARHGEF5 RBM7 NHS SORBS1 RIMS2 FRMD4B CASK	4.29e-05	1256	74	15	int:YWHAE
Interaction	PSG9 interactions	NEFM NEFL CELSR3	6.96e-05	22	74	3	int:PSG9
Interaction	ARHGAP42 interactions	NEFL GLI1 SORBS1 PLEC	6.99e-05	60	74	4	int:ARHGAP42
Interaction	FGD4 interactions	CCNL2 NEFL SORBS1 PLEC	9.01e-05	64	74	4	int:FGD4
Cytoband	Ensembl 112 genes in cytogenetic band chr8p21	EBF2 NEFM NEFL PDLIM2	7.01e-05	135	74	4	chr8p21
Cytoband	8p21	NEFM NEFL	4.78e-04	20	74	2	8p21
GeneFamily	CD molecules\|Mucins	MUC17 MUC16 MUC12 MUC3A	4.75e-07	21	56	4	648
GeneFamily	Intermediate filaments Type IV	NEFM NEFL	1.40e-04	6	56	2	611
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A KMT2C SETD2	1.57e-04	34	56	3	487
GeneFamily	PDZ domain containing	TIAM1 RIMS2 PDLIM2 CASK	1.26e-03	152	56	4	1220
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	CACNB1 CASK	2.92e-03	26	56	2	904
GeneFamily	Immunoglobulin like domain containing	FCGR1A DSCAM FCGR1BP IL1RAP	3.00e-03	193	56	4	594
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	EBF2 TANC2 SEMA6D CELSR3 DSCAM SRRM4 VCAN SORBS1 UBN2 RIMS2 FRMD4B WNK3 C2CD5 CASK	2.24e-06	1106	74	14	M39071
Coexpression	DESCARTES_ORGANOGENESIS_CHOLINERGIC_NEURONS	TANC2 NEFM NEFL SEMA6D GPR149	2.47e-06	76	74	5	MM3658
Coexpression	GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN	CACNB1 SEMA6D SKAP1 SORBS1 PLEC FRMD4B	8.76e-06	170	74	6	M9445
Coexpression	GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	SETD1A ZSWIM8 SETD2 POM121 SMCR8 JMJD1C	2.14e-05	199	74	6	M9501
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 SEMA6D TIAM1 GLI1 NHS PLPPR3 SORBS1	3.89e-08	197	74	7	ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SGCZ DSCAM VCAN RIMS2 IL1RAP CASK	1.03e-06	200	74	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SGCZ DSCAM VCAN RIMS2 IL1RAP CASK	1.03e-06	200	74	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SGCZ DSCAM VCAN RIMS2 IL1RAP CASK	1.03e-06	200	74	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SGCZ DSCAM VCAN RIMS2 IL1RAP CASK	1.03e-06	200	74	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SGCZ DSCAM VCAN RIMS2 IL1RAP CASK	1.03e-06	200	74	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SGCZ DSCAM VCAN RIMS2 IL1RAP CASK	1.03e-06	200	74	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 CACNB1 KIAA1328 NHS POM121C	3.68e-06	140	74	5	0e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6D DSCAM SKAP1 LAD1 FRMD4B	6.05e-06	155	74	5	c58a5fb8d853f12204e961d633e83452eb12a659
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6D DSCAM SKAP1 LAD1 FRMD4B	6.05e-06	155	74	5	9cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FOXO1 SEMA6D SORBS1 IL1RAP ITGB4	8.95e-06	168	74	5	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SGCZ SRRM4 LAD1 RIMS2 WNK3	9.21e-06	169	74	5	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	HIF1A SLC25A18 TMPRSS13 ARHGEF5 NHS	9.21e-06	169	74	5	625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCell	facs-Marrow-B-cells-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STBD1 FCGR1BP GPR149 VCAN CASK	9.47e-06	170	74	5	6e82e41acd1299aa549a32ac036b39754abdf376
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 SEMA6D BARD1 CCDC168 IL1RAP	9.47e-06	170	74	5	49fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCell	facs-Marrow-B-cells-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STBD1 FCGR1BP GPR149 VCAN CASK	9.47e-06	170	74	5	18cd941bf3ca7cc0b6af1317bd2619d283353de0
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CELSR3 TIAM1 BARD1 MUC12 CASK	1.00e-05	172	74	5	eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	MUC17 MUC16 TMC5 MUC3A ITGB4	1.35e-05	183	74	5	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	FOCAD SETD1A FCGR1BP WRAP53 FRMD4B	1.35e-05	183	74	5	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	PCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NEFM NEFL CELSR3 SRRM4 RIMS2	1.35e-05	183	74	5	9dfb398b9995d562864fe688861a831ada0814cd
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NEFM NEFL GPR149 SRRM4 RIMS2	1.39e-05	184	74	5	571136c832cb8c08457744152231537aa8e8abd7
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SEMA6D DSCAM UNC13D LRRN4 PDLIM2	1.39e-05	184	74	5	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SEMA6D DSCAM UNC13D LRRN4 PDLIM2	1.39e-05	184	74	5	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	MUC17 MUC16 TMC5 MUC3A ITGB4	1.39e-05	184	74	5	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 VIM SLC25A18 VCAN ITGB4	1.39e-05	184	74	5	22c18964818fc9c8f18051f836d718937b0d8d12
ToppCell	PCW_05-06-Neuronal-Neuronal_postreplicative\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NEFM NEFL CELSR3 SRRM4 RIMS2	1.43e-05	185	74	5	512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCell	Control-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	FOXO1 TIAM1 SKAP1 FRMD4B CASK	1.43e-05	185	74	5	e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMPRSS13 LAD1 TMC5 ITGB4 BAIAP2L2	1.46e-05	186	74	5	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KMT2C VCAN MUC16 PLEC JMJD1C	1.46e-05	186	74	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FOCAD SETD1A FCGR1BP VCAN FRMD4B	1.46e-05	186	74	5	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 FOXO1 HIF1A NHS RIMS2	1.50e-05	187	74	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Tregs\|Lung / Manually curated celltypes from each tissue	FOXO1 CCDC88C SKAP1 FRMD4B CASK	1.54e-05	188	74	5	604f340052807bd902915eca942a97ccc36b42e0
ToppCell	IPF-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	FOXO1 TIAM1 SKAP1 FRMD4B CASK	1.58e-05	189	74	5	7a260485c2a7c743c14d048e5e480ae0a9b8e32c
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FOXO1 CCDC88C GLI1 SKAP1 CFAP97	1.58e-05	189	74	5	d05e043d0874b8563b9f5514f6c884b35c603e3a
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FOXO1 TIAM1 SKAP1 FRMD4B CASK	1.62e-05	190	74	5	b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMPRSS13 LAD1 TMC5 ITGB4 BAIAP2L2	1.62e-05	190	74	5	576c45a30a4808b47433bc6c2c41396135556c40
ToppCell	COPD-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	FOXO1 TIAM1 SKAP1 FRMD4B CASK	1.66e-05	191	74	5	3ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	VIM NEFL TIAM1 CFAP97 CASK	1.66e-05	191	74	5	9c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Tregs\|lymph-node_spleen / Manually curated celltypes from each tissue	FOXO1 TIAM1 SKAP1 FRMD4B CASK	1.70e-05	192	74	5	91a4d06e8d1d1fe2ce5f72668108513bd2a72c4d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SGCZ STBD1 VCAN IL1RAP FRMD4B	1.75e-05	193	74	5	64a37dae3d631713b06d94691f5dcdb200dfef5e
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 TMPRSS13 ARHGEF5 LAD1 ITGB4	1.75e-05	193	74	5	22ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCell	COVID-19_Mild-CD4+_Tcm\|COVID-19_Mild / Disease condition and Cell class	VIM NEFL TIAM1 FRMD4B CASK	1.79e-05	194	74	5	3be2b1c81e668ffdf593ff41d3ba211c26d77671
ToppCell	BLOOD--(1)_T_cell-(1)_EM_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	VIM NEFL TIAM1 PLEC FRMD4B	1.84e-05	195	74	5	4b8831ed8fb73579f49604eeda8a3b2344e69f0e
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	FOXO1 VIM TIAM1 FRMD4B CASK	1.88e-05	196	74	5	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	FOXO1 VIM JMJD1C FRMD4B CASK	1.88e-05	196	74	5	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 TIAM1 GLI1 VCAN PLPPR3	1.93e-05	197	74	5	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ATF6 HIF1A TIAM1 VCAN JMJD1C	1.93e-05	197	74	5	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	KMT2C HIF1A PHF3 BCLAF1 JMJD1C	1.93e-05	197	74	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	COVID-19_Severe-Classical_Monocyte\|World / disease group, cell group and cell class	HIF1A FCGR1A FCGR1BP VCAN IL1RAP	1.93e-05	197	74	5	344801997b89bd81d8d5c3c872934de523233a8d
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 VIM SEMA6D VCAN PDLIM2	1.98e-05	198	74	5	9541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	KMT2C HIF1A PHF3 BCLAF1 JMJD1C	1.98e-05	198	74	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KMT2C HIF1A PHF3 BCLAF1 JMJD1C	1.98e-05	198	74	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C HIF1A MUC17 VCAN JMJD1C	1.98e-05	198	74	5	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 SEMA6D NHS SORBS1 ITGB4	2.02e-05	199	74	5	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	5'-Adult-SmallIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6D MUC17 TMC5 MUC3A BAIAP2L2	2.02e-05	199	74	5	a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 VIM TIAM1 VCAN PDLIM2	2.02e-05	199	74	5	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 SEMA6D GLI1 SORBS1 ITGB4	2.02e-05	199	74	5	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 VIM SEMA6D GLI1 SORBS1	2.02e-05	199	74	5	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FOXO1 VIM HIF1A PLEC ITGB4	2.02e-05	199	74	5	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / Treatment groups by lineage, cell group, cell type	FOXO1 HIF1A SEMA6D PLEC ITGB4	2.07e-05	200	74	5	b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C SETD2 PHF3 BCLAF1 JMJD1C	2.07e-05	200	74	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	KMT2C SETD2 HIF1A PHF3 BCLAF1	2.07e-05	200	74	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NEFM NEFL MUC17 LAD1	4.95e-05	121	74	4	05c40fd39e6b6275f35aaad835f95a81fcbb0990
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	VCAN CCDC168 LRRN4 JMJD1C	7.58e-05	135	74	4	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	primary_visual_cortex\|World / Per Region, Lineage, Cell class, Cell type, Cell subtype	NEFM TIAM1 SORBS1 RIMS2	8.97e-05	141	74	4	605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	VCAN CCDC168 LRRN4 JMJD1C	1.11e-04	149	74	4	768877bade04ca0321593b8470b5011ad8270431
ToppCell	BAL-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	TIAM1 VCAN NHS UNC13D	1.39e-04	158	74	4	73f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCell	356C-Fibroblasts-Fibroblast-D-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SLC25A18 FCGR1A FCGR1BP CCDC168	1.43e-04	159	74	4	299e2162a82e31196d7f3a110c2db622349edfff
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOCAD ZBTB49 STBD1 SRRM4	1.43e-04	159	74	4	6ec5489d55667e53bd9c021ada7de458bfef43a3
ToppCell	356C-Fibroblasts-Fibroblast-D\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SLC25A18 FCGR1A FCGR1BP CCDC168	1.43e-04	159	74	4	0a3a363b30a8c741e1a3e2525725108d03c21776
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOCAD ZBTB49 STBD1 SRRM4	1.53e-04	162	74	4	075f73ff10e1a7f5695e014e47acc4db513e9cfb
ToppCell	severe_influenza-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	NEFM NEFL SKAP1 CASK	1.53e-04	162	74	4	7137990e6e1473665911e39a22092a05ae25ce74
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VCAN NHS LRRN4 RIMS2	1.61e-04	164	74	4	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-Tregs\|bone_marrow / Manually curated celltypes from each tissue	FOXO1 TIAM1 FRMD4B CASK	1.64e-04	165	74	4	1ae1ad4e1fe19b6eefff0f9a03d58a384f169759
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	FOXO1 HIF1A SLC25A18 NHS	1.68e-04	166	74	4	c73fce59256ad501864f44f76cfae2fc33b3777e
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNB1 CCDC168 LRRN4 WNK3	1.76e-04	168	74	4	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	FOXO1 CCDC88C SKAP1 CASK	1.80e-04	169	74	4	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|Monocyte / Lineage, cell class and subclass	VIM HIF1A FCGR1A VCAN	1.80e-04	169	74	4	7c3144a6599787f28662f5b22b8e45f4a115aeda
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMPRSS13 SRRM4 SORBS1 WNK3	1.84e-04	170	74	4	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SGCZ DSCAM SKAP1 RIMS2	1.88e-04	171	74	4	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VIM SLC25A18 VCAN ITGB4	1.93e-04	172	74	4	55fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC88C TMPRSS13 SKAP1 BAIAP2L2	1.97e-04	173	74	4	15a77f6aac968b7a1afea4f60aedbb95b9d0f765
ToppCell	droplet-Liver-Npc-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB1 SEMA6D CELSR3 FCGR1BP	1.97e-04	173	74	4	9ba55e21d1037ec3150d77895e52f0b051df65da
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEFM DSCAM RIMS2 WNK3	1.97e-04	173	74	4	30fa8c14c8a1f546f380132c0c28a61e6a2f9fc4
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	FOXO1 SEMA6D IL1RAP ITGB4	1.97e-04	173	74	4	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF5 PLEC TMC5 PDLIM2	2.01e-04	174	74	4	2fbdb62e269acf4447b171700a615e878dde7f9f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF5 PLEC TMC5 PDLIM2	2.01e-04	174	74	4	7c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 FOXO1 SKAP1 WNK3	2.01e-04	174	74	4	5f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR149 BARD1 NHS FRMD4B	2.06e-04	175	74	4	9d797888edb39fd12fd9cfc698a42b7bed19a5b5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 SEMA6D CCDC168 IL1RAP	2.06e-04	175	74	4	d4827b4dfad07f11cbdd47fbed287af1afb9b1b8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 DSCAM SKAP1 WNK3	2.10e-04	176	74	4	25ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 FOXO1 DSCAM WNK3	2.10e-04	176	74	4	c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 TIAM1 SKAP1 WNK3	2.10e-04	176	74	4	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	facs-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIM SEMA6D DSCAM SKAP1	2.15e-04	177	74	4	17065d37fd41f04f67282bee00365daa185e8355
ToppCell	facs-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIM SEMA6D DSCAM SKAP1	2.15e-04	177	74	4	6e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCell	facs-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIM SEMA6D DSCAM SKAP1	2.15e-04	177	74	4	9ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CCDC88C KMT2C LAD1 KIAA1328	2.15e-04	177	74	4	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SGCZ GPR149 NHS FRMD4B	2.20e-04	178	74	4	6ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMPRSS13 LAD1 NHS BAIAP2L2	2.20e-04	178	74	4	b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 TIAM1 SKAP1 WNK3	2.20e-04	178	74	4	51d2188406f04329311b2efd1108fc36617a860e
Drug	FG 9041	NEFM VIM NEFL	1.82e-06	8	74	3	ctd:C056723
Drug	Excitatory Amino Acid Antagonists	NEFM VIM NEFL	2.73e-06	9	74	3	ctd:D018691
Drug	deoxynivalenol	FOXO1 VIM SETD1A ATF6 HIF1A BCLAF1 MUC16 UNC13D PLEC PDLIM2	3.46e-06	481	74	10	ctd:C007262
Drug	diphenylditelluride	NEFM VIM NEFL	7.10e-06	12	74	3	ctd:C434247
Drug	KN 93	NEFM VIM NEFL HIF1A	1.51e-05	46	74	4	ctd:C072105
Drug	6-Cyano-7-nitroquinoxaline-2,3-dione	NEFM VIM NEFL	1.79e-05	16	74	3	ctd:D018750
Drug	NSC716727	SETD2 HIF1A	3.12e-05	3	74	2	CID000402597
Drug	NSC-643735	SETD2 HIF1A	3.12e-05	3	74	2	CID000457943
Drug	Pralidoxime chloride [51-15-0]; Down 200; 23.2uM; PC3; HT_HG-U133A	CCDC88C WRAP53 PDLIM2 GRAMD4 LRRC41 CASK	4.17e-05	195	74	6	6283_DN
Drug	Lithocholic acid [434-13-9]; Down 200; 10.6uM; HL60; HT_HG-U133A	CACNB1 PHF3 WRAP53 TMC5 ITGB4 LRRC41	4.29e-05	196	74	6	2571_DN
Drug	Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; HL60; HT_HG-U133A	FOXO1 CACNB1 CELSR3 LAD1 ITGB4 PDLIM2	4.29e-05	196	74	6	2160_DN
Drug	Niacin [59-67-6]; Down 200; 32.4uM; MCF7; HT_HG-U133A	ZSWIM8 UBAP2L PHF3 WRAP53 GRAMD4 LRRC41	4.42e-05	197	74	6	5301_DN
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; HL60; HT_HG-U133A	CACNB1 CELSR3 PHF3 PLEC PDLIM2 LRRC41	4.42e-05	197	74	6	2558_DN
Drug	Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; HL60; HT_HG-U133A	FOXO1 TIAM1 PHF3 SORBS1 RIMS2 PDLIM2	4.42e-05	197	74	6	2404_UP
Drug	Amodiaquin dihydrochloride dihydrate [6398-98-7]; Down 200; 8.6uM; MCF7; HT_HG-U133A	FOCAD ZSWIM8 SETD2 TIAM1 UBAP2L CASK	4.54e-05	198	74	6	6224_DN
Drug	ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA	FOXO1 SETD2 UBAP2L PHF3 WRAP53 LRRC41	4.54e-05	198	74	6	871_DN
Drug	Tadjakonine [11087-94-8]; Down 200; 7.4uM; HL60; HT_HG-U133A	FOXO1 SETD1A CELSR3 PHF3 ITGB4 LRRC41	4.67e-05	199	74	6	2165_DN
Drug	Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; HL60; HT_HG-U133A	NEFM ZSWIM8 SEMA6D DSCAM PHF3 LAD1	4.67e-05	199	74	6	2545_UP
Drug	Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HT_HG-U133A	EBF2 CACNB1 SEMA6D DSCAM PHF3 SORBS1	4.67e-05	199	74	6	4068_UP
Drug	BAPPs	NEFM NEFL	6.23e-05	4	74	2	CID000134312
Drug	3-methyl-2,5-hexanedione	NEFM NEFL	6.23e-05	4	74	2	CID000107281
Drug	dihydrotanshinone I	SETD2 HIF1A	6.23e-05	4	74	2	CID005316743
Drug	AC1L1HOS	SETD2 HIF1A BARD1	7.20e-05	25	74	3	CID000004223
Drug	2-isopropylpentanoic acid	NEFM NEFL	1.04e-04	5	74	2	CID000147513
Drug	quindoxin	SETD2 HIF1A	1.04e-04	5	74	2	CID000072073
Drug	ammoniacal silver nitrate solution	NEFM NEFL	1.04e-04	5	74	2	CID000062774
Drug	1-phenylpentan-3-amine	NEFM VIM NEFL	1.13e-04	29	74	3	CID005195771
Disease	Neurodevelopmental Disorders	TANC2 KMT2C SETD2 DSCAM CASK	2.87e-06	93	70	5	C1535926
Disease	Adenoid Cystic Carcinoma	KMT2C SETD2 VCAN ITGB4 JMJD1C	4.11e-06	100	70	5	C0010606
Disease	Epidermolysis Bullosa Simplex With Pyloric Atresia	PLEC ITGB4	5.55e-06	2	70	2	C2677349
Disease	Junctional epidermolysis bullosa with pyloric atresia	PLEC ITGB4	5.55e-06	2	70	2	cv:C5676875
Disease	EPIDERMOLYSIS BULLOSA, JUNCTIONAL 5B, WITH PYLORIC ATRESIA	PLEC ITGB4	5.55e-06	2	70	2	226730
Disease	Epidermolysis bullosa with pyloric atresia	PLEC ITGB4	1.66e-05	3	70	2	C1856934
Disease	prostate carcinoma, breast carcinoma, ovarian carcinoma	CCDC88C TPCN2 ARHGEF5	3.59e-05	27	70	3	EFO_0000305, EFO_0001075, EFO_0001663
Disease	retinal degeneration (biomarker_via_orthology)	FCGR1A FCGR1BP BARD1	4.01e-05	28	70	3	DOID:8466 (biomarker_via_orthology)
Disease	mean fractional anisotropy measurement	NEFL VCAN PLEC BAIAP2L2	7.86e-05	95	70	4	EFO_0008399
Disease	Aplasia Cutis Congenita	PLEC ITGB4	8.27e-05	6	70	2	C0282160
Disease	neuroimaging measurement	NEFM CCDC88C NEFL TPCN2 VCAN PLEC TMC5 POM121C JMJD1C FRMD4B	2.06e-04	1069	70	10	EFO_0004346
Disease	susceptibility to influenza measurement	NEFM NEFL	2.47e-04	10	70	2	EFO_0803537
Disease	plasminogen activator inhibitor 1 measurement	MUC17 MUC12 FRMD4B	2.91e-04	54	70	3	EFO_0004792
Disease	nucleus accumbens volume change measurement	DSCAM MUC16	3.01e-04	11	70	2	EFO_0021493
Disease	ovarian cancer (is_implicated_in)	BARD1 MUC16 WRAP53	3.24e-04	56	70	3	DOID:2394 (is_implicated_in)
Disease	congenital hypothyroidism (implicated_via_orthology)	NEFM NEFL	4.96e-04	14	70	2	DOID:0050328 (implicated_via_orthology)
Disease	colorectal cancer (is_marker_for)	SETD2 HIF1A GLI1 WRAP53	5.38e-04	157	70	4	DOID:9256 (is_marker_for)
Disease	Prostatic Neoplasms	FOXO1 VIM KMT2C SETD2 HIF1A ARHGEF5 UNC13D	6.42e-04	616	70	7	C0033578
Disease	Malignant neoplasm of prostate	FOXO1 VIM KMT2C SETD2 HIF1A ARHGEF5 UNC13D	6.42e-04	616	70	7	C0376358
Disease	Sjogren's syndrome (is_marker_for)	NEFL MUC16	1.48e-03	24	70	2	DOID:12894 (is_marker_for)
Disease	immature platelet count	SETD2 PLEC JMJD1C	2.07e-03	106	70	3	EFO_0803544
Disease	white matter microstructure measurement	VCAN UNC13D PLEC FRMD4B BAIAP2L2	2.35e-03	390	70	5	EFO_0005674

Protein segments in the cluster

Peptide	Gene	Start	Entry
QYSPLRASRTSSATS	CFAP97	486	Q9P2B7
PSTLSSSSYRRVMSS	BARD1	396	Q99728
DPTSTLSNTVSYERS	VCAN	2501	P13611
RQGSAESYTSRPSDS	CACNB1	56	Q02641
RSGRDYSTVSASPTA	ARHGEF5	651	Q12774
SRRLQTTSSRSYVPS	GRAMD4	411	Q6IC98
RNTSSISPRGYSSSS	EBF2	451	Q9HAK2
ASSSYSVSSPRSVDS	ATF6	96	P18850
SVSSPRSVDSYSSTQ	ATF6	101	P18850
TATQTSTPSYRITSA	FCGR1BP	61	Q92637
STPSYRITSASVNDS	FCGR1BP	66	Q92637
ITSSSATPYRVDTSL	MUC16	10351	Q8WXI7
YRTQSSSCERDSPST	CASK	571	O14936
SPTQRTYSSSLKRSS	LAD1	356	O00515
TYSSSLKRSSPRTIS	LAD1	361	O00515
ISSSRTSVSQIPFYS	KMT2C	3441	Q8NEZ4
TSAYSRATSSSSSQP	MAGEB4	331	O15481
SPRRSSSDEQGLSYS	IL1RAP	551	Q9NPH3
TTSATSSPYRDTQSR	HIF1A	651	Q16665
RENYSRVASSSSSPK	JMJD1C	1046	Q15652
RTPSASSLYSGSAQS	BAIAP2L2	296	Q6UXY1
YVSRPSSLESSRNTS	CCDC88C	1566	Q9P219
YPTSLTSALTDSTTR	MUC3A	1841	Q02505
SAYTVSRRSSLASPF	GLI1	551	P08151
SHSTTLPRDYSTLTS	ITGB4	1501	P16144
TTASPSLQHTTSRYE	KIAA1328	496	Q86T90
GIPSSSRNAITSSYS	POM121C	381	A8CG34
SQSSTQVRSPSLRYS	GPR149	641	Q86SP6
SQSSLESSTGPSYSR	RIMS2	1396	Q9UQ26
PSSSRNAITSSYSST	POM121	406	Q96HA1
PSSRASSYSSVSSTN	FRMD4B	941	Q9Y2L6
STFRPRTSSNASTIS	FOXO1	311	Q12778
QGSASAPSTSRSYTT	SLC25A18	141	Q9H1K4
SREQSYSRSPSRSAS	CCNL2	386	Q96S94
SRSPRSSSSRSSSPY	BCLAF1	136	Q9NYF8
TATQTSTPSYRITSA	FCGR1A	61	P12314
STPSYRITSASVNDS	FCGR1A	66	P12314
LSSSQSSYSPSNREA	KCMF1	181	Q9P0J7
TTKSRTSYSSAPLTE	CCDC168	6906	Q8NDH2
TGSLSQPASRYSSRE	CELSR3	3056	Q9NYQ7
PSKSYSRQSSSSDTD	C2CD5	296	Q86YS7
TLSSSQSRASVPTDY	FOCAD	1341	Q5VW36
SNSSVFPRAASTTRT	LRRN4	441	Q8WUT4
ADTRTPVTTYSQASS	MUC17	1951	Q685J3
YSVSPSQDTDRARSS	DSCAM	1786	O60469
NSSPTSTSPSRYERT	RBM7	106	Q9Y580
SSAQPDTSYVASSSR	WRAP53	236	Q9BUR4
SASSSTSSYKRAPAS	LRRC41	366	Q15345
TNDPYRSLSNSSTAT	NHS	956	Q6T4R5
SSSVGSPTRQTYQST	TANC2	1471	Q9HCD6
SSPSSSSSRQTVYEL	SGCZ	256	Q96LD1
AYSSSTTSTSFKPRR	SETD1A	286	O15047
TTSTSFKPRRSENSY	SETD1A	291	O15047
YTESQSSLRSSYSSP	PDLIM2	111	Q96JY6
SYVSSVASTSSDRIP	SMCR8	676	Q8TEV9
SLDSAQSSRSTSYSP	C12orf40	471	Q86WS4
QSSRSTSYSPRPTDS	C12orf40	476	Q86WS4
SRTVPSTTTSSNYLA	UBN2	1001	Q6ZU65
SARSASVTTSPTRVY	TMPRSS13	106	Q9BYE2
STQTRRYPSSISSSP	UBAP2L	596	Q14157
LSRRSNATNSSYSPT	TIAM1	346	Q13009
PATSETSNSRSYSEV	STBD1	126	O95210
VPRYSGSSSSTRTQA	RP1L1	701	Q8IWN7
SASSDSSQYRSPSDR	PLPPR3	561	Q6T4P5
SSQYRSPSDRDSASI	PLPPR3	566	Q6T4P5
VTLRASSSYRETPSS	SORBS1	71	Q9BX66
RASPRYTQSRSTSSE	SRRM4	411	A7MD48
ASRPSSSRSYVTTST	VIM	21	P08670
TFTSRSTSPRTSTNF	PHF3	1781	Q92576
RSRSSSVGSSSSYPI	PLEC	4381	Q15149
EETSPCSSRSSQSYR	SETD2	1081	Q9BYW2
SFYSSSRPTTASQRS	ZSWIM8	1026	A7E2V4
PLGSRASSTTYRNSE	ZBTB49	726	Q6ZSB9
TRSNAYSAASRTSPD	TMC5	86	Q6UXY8
SRQSSYTSNGTLPRT	SEMA6D	1026	Q8NFY4
RRATSASRSQPSYTV	UNC13D	286	Q70J99
TSQDRRSYEFTATSP	SKAP1	181	Q86WV1
TPSSLTSTADVRYRA	TPCN2	101	Q8NHX9
APVTNSSSYSTTSVR	WNK3	971	Q9BYP7
SSSYSTTSVRAVPAE	WNK3	976	Q9BYP7
STILYSSSRSPDQTL	MUC12	4881	Q9UKN1
SSYSAPVSSSLSVRR	NEFL	41	P07196
PVSSSLSVRRSYSSS	NEFL	46	P07196
SRGSPSTVSSSYKRS	NEFM	41	P07197