Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metallocarboxypeptidase activity	CPA6 FOLH1 CPZ AGBL4 FOLH1B	1.13e-06	31	121	5	GO:0004181
GeneOntologyMolecularFunction	carboxypeptidase activity	CPA6 FOLH1 CPZ AGBL4 FOLH1B	1.16e-05	49	121	5	GO:0004180
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3C3 PIP5K1B PIP4K2B PIPSL	1.73e-05	26	121	4	GO:0052742
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 5-kinase activity	PIP5K1B PIP4K2B PIPSL	1.78e-05	9	121	3	GO:0016308
GeneOntologyMolecularFunction	tetrahydrofolyl-poly(glutamate) polymer binding	FOLH1 FOLH1B	3.64e-05	2	121	2	GO:1904493
GeneOntologyMolecularFunction	Ac-Asp-Glu binding	FOLH1 FOLH1B	3.64e-05	2	121	2	GO:1904492
GeneOntologyMolecularFunction	metalloexopeptidase activity	CPA6 FOLH1 CPZ AGBL4 FOLH1B	6.64e-05	70	121	5	GO:0008235
GeneOntologyMolecularFunction	RNA 7-methylguanosine cap binding	CYFIP2 CYFIP1 EIF4E2	7.52e-05	14	121	3	GO:0000340
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	ATR STYK1 IRAK2 SNRK GCK GRK2 GRK3 PIK3C3 BRD4 PIP5K1B PIP4K2B PIPSL PLK4 CDK7	1.01e-04	709	121	14	GO:0016773
GeneOntologyMolecularFunction	lipid kinase activity	PIK3C3 PIP5K1B PIP4K2B PIPSL	1.09e-04	41	121	4	GO:0001727
GeneOntologyMolecularFunction	beta-adrenergic receptor kinase activity	GRK2 GRK3	2.17e-04	4	121	2	GO:0047696
GeneOntologyMolecularFunction	kinase activity	ATR STYK1 IRAK2 SNRK GCK GRK2 GRK3 PIK3C3 BRD4 PIP5K1B PIP4K2B PIPSL PLK4 CDK7	2.19e-04	764	121	14	GO:0016301
GeneOntologyMolecularFunction	RNA cap binding	CYFIP2 CYFIP1 EIF4E2	2.67e-04	21	121	3	GO:0000339
GeneOntologyMolecularFunction	phospholipid scramblase activity	ANO1 ANO5 CLPTM1L	3.52e-04	23	121	3	GO:0017128
GeneOntologyMolecularFunction	exopeptidase activity	CPA6 FOLH1 CPZ AGBL4 FOLH1B	5.54e-04	110	121	5	GO:0008238
GeneOntologyMolecularFunction	G protein-coupled receptor kinase activity	GRK2 GRK3	7.50e-04	7	121	2	GO:0004703
GeneOntologyMolecularFunction	phospholipid transporter activity	ANO1 ANO5 CLPTM1L OSBPL10	1.06e-03	74	121	4	GO:0005548
GeneOntologyMolecularFunction	metallopeptidase activity	CPA6 FOLH1 CPZ AGBL4 ADAMTS20 FOLH1B	1.39e-03	200	121	6	GO:0008237
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat kinase activity	BRD4 CDK7	1.59e-03	10	121	2	GO:0008353
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ATR STYK1 IRAK2 SNRK GCK GRK2 GRK3 PIK3C3 BRD4 PIP5K1B PIP4K2B PIPSL PLK4 CDK7	1.64e-03	938	121	14	GO:0016772
GeneOntologyMolecularFunction	tRNA binding	TRMT10B RPUSD4 XPO5 WDR6	1.94e-03	87	121	4	GO:0000049
GeneOntologyBiologicalProcess	C-terminal protein deglutamylation	FOLH1 AGBL4 FOLH1B	3.70e-06	6	119	3	GO:0035609
GeneOntologyBiologicalProcess	protein deglutamylation	FOLH1 AGBL4 FOLH1B	1.03e-05	8	119	3	GO:0035608
GeneOntologyBiologicalProcess	peptidyl-glutamic acid modification	FOLH1 TTLL8 AGBL4 FOLH1B	2.24e-05	29	119	4	GO:0018200
GeneOntologyBiologicalProcess	post-translational protein modification	DCAF6 ZBTB16 FOLH1 C10orf90 COPS3 BCL11A HUWE1 BIRC6 AGBL4 KLHL7 LTN1 CCAR1 FOLH1B MINAR1 HERC2 HERC6 ZNF738 LARGE1	4.33e-05	1074	119	18	GO:0043687
Domain	ARM-type_fold	ATR COPG2 HUWE1 ECPAS AP1G1 XPO5 PIK3C3 LTN1 TAF2 NIPBL AP3D1	1.19e-05	339	120	11	IPR016024
Domain	Cytoplasmic_FMR1-int	CYFIP2 CYFIP1	4.09e-05	2	120	2	IPR008081
Domain	FragX_IP	CYFIP2 CYFIP1	4.09e-05	2	120	2	PF05994
Domain	ARM-like	ATR COPG2 HUWE1 ECPAS AP1G1 XPO5 LTN1 NIPBL AP3D1	6.24e-05	270	120	9	IPR011989
Domain	RGS	RGSL1 RGS1 GRK2 GRK3	7.27e-05	35	120	4	PF00615
Domain	RGS	RGSL1 RGS1 GRK2 GRK3	8.14e-05	36	120	4	PS50132
Domain	HEAT_REPEAT	ATR COPG2 ECPAS NIPBL AP3D1	8.73e-05	70	120	5	PS50077
Domain	Clathrin/coatomer_adapt-like_N	COPG2 AP1G1 AP3D1	1.11e-04	15	120	3	IPR002553
Domain	Adaptin_N	COPG2 AP1G1 AP3D1	1.11e-04	15	120	3	PF01602
Domain	RGS	RGSL1 RGS1 GRK2 GRK3	1.12e-04	39	120	4	IPR016137
Domain	Zn_pept	CPA6 CPZ AGBL4	1.97e-04	18	120	3	SM00631
Domain	CARBOXYPEPT_ZN_2	CPA6 CPZ AGBL4	2.32e-04	19	120	3	PS00133
Domain	DUF1394	CYFIP2 CYFIP1	2.44e-04	4	120	2	PF07159
Domain	DUF1394	CYFIP2 CYFIP1	2.44e-04	4	120	2	IPR009828
Domain	CARBOXYPEPT_ZN_1	CPA6 CPZ AGBL4	2.72e-04	20	120	3	PS00132
Domain	Peptidase_M14	CPA6 CPZ AGBL4	4.17e-04	23	120	3	PF00246
Domain	Peptidase_M14	CPA6 CPZ AGBL4	4.17e-04	23	120	3	IPR000834
Domain	-	ATR COPG2 ECPAS AP1G1 XPO5 NIPBL AP3D1	5.82e-04	222	120	7	1.25.10.10
Domain	TFR_dimer	FOLH1 FOLH1B	6.04e-04	6	120	2	PF04253
Domain	-	FOLH1 FOLH1B	6.04e-04	6	120	2	1.20.930.40
Domain	HECT	HUWE1 HERC2 HERC6	6.76e-04	27	120	3	PF00632
Domain	HECTc	HUWE1 HERC2 HERC6	6.76e-04	27	120	3	SM00119
Domain	HECT_dom	HUWE1 HERC2 HERC6	6.76e-04	27	120	3	IPR000569
Domain	HECT	HUWE1 HERC2 HERC6	6.76e-04	27	120	3	PS50237
Domain	GPCR_kinase	GRK2 GRK3	8.42e-04	7	120	2	IPR000239
Domain	Anoct_dimer	ANO1 ANO5	8.42e-04	7	120	2	PF16178
Domain	Anoct_dimer	ANO1 ANO5	8.42e-04	7	120	2	IPR032394
Domain	PInositol-4-P-5-kinase	PIP5K1B PIP4K2B	8.42e-04	7	120	2	IPR023610
Domain	TFR-like_dimer_dom	FOLH1 FOLH1B	8.42e-04	7	120	2	IPR007365
Domain	PIPKc	PIP5K1B PIP4K2B	1.12e-03	8	120	2	SM00330
Domain	-	PIP5K1B PIP4K2B	1.12e-03	8	120	2	3.30.800.10
Domain	PIP5K	PIP5K1B PIP4K2B	1.12e-03	8	120	2	PF01504
Domain	PIPK	PIP5K1B PIP4K2B	1.12e-03	8	120	2	PS51455
Domain	PInositol-4-P-5-kinase_N	PIP5K1B PIP4K2B	1.12e-03	8	120	2	IPR027484
Domain	PInositol-4-P-5-kinase_C	PIP5K1B PIP4K2B	1.12e-03	8	120	2	IPR027483
Domain	-	PIP5K1B PIP4K2B	1.12e-03	8	120	2	3.30.810.10
Domain	PInositol-4-P-5-kinase_core	PIP5K1B PIP4K2B	1.12e-03	8	120	2	IPR002498
Domain	RGS	RGS1 GRK2 GRK3	1.46e-03	35	120	3	SM00315
Domain	Anoctamin	ANO1 ANO5	1.78e-03	10	120	2	PF04547
Domain	Anoctamin	ANO1 ANO5	1.78e-03	10	120	2	IPR007632
Domain	Peptidase_M28	FOLH1 FOLH1B	2.59e-03	12	120	2	IPR007484
Domain	Coatomer/clathrin_app_Ig-like	COPG2 AP1G1	2.59e-03	12	120	2	IPR013041
Domain	Peptidase_M28	FOLH1 FOLH1B	2.59e-03	12	120	2	PF04389
Domain	FERM-adjacent	EPB41 FRMD3	3.05e-03	13	120	2	IPR014847
Domain	FA	EPB41 FRMD3	3.05e-03	13	120	2	SM01195
Domain	FA	EPB41 FRMD3	3.05e-03	13	120	2	PF08736
Domain	PH	NET1 PLEKHD1 GRK2 GRK3 OSBPL10 ARHGEF3	3.64e-03	229	120	6	PF00169
Domain	-	NET1 PLEKHD1 GRK2 GRK3 OSBPL10 ARHGEF3 EPB41 FRMD3	3.77e-03	391	120	8	2.30.29.30
Domain	PI3/4_kinase_CS	ATR PIK3C3	4.07e-03	15	120	2	IPR018936
Domain	-	ATR PIK3C3	4.63e-03	16	120	2	1.10.1070.11
Domain	PI3Kc	ATR PIK3C3	4.63e-03	16	120	2	SM00146
Domain	PI3/4_kinase_cat_dom	ATR PIK3C3	5.86e-03	18	120	2	IPR000403
Domain	PI3_PI4_kinase	ATR PIK3C3	5.86e-03	18	120	2	PF00454
Domain	PI3_4_KINASE_3	ATR PIK3C3	5.86e-03	18	120	2	PS50290
Domain	PI3_4_KINASE_1	ATR PIK3C3	5.86e-03	18	120	2	PS00915
Domain	PI3_4_KINASE_2	ATR PIK3C3	5.86e-03	18	120	2	PS00916
Domain	HEAT	ATR ECPAS NIPBL	6.17e-03	58	120	3	IPR000357
Domain	PH_dom-like	NET1 PLEKHD1 GRK2 GRK3 OSBPL10 ARHGEF3 EPB41 FRMD3	6.26e-03	426	120	8	IPR011993
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	SIKE1 RPUSD4 NADSYN1 CYFIP1 PIK3C3 LTN1 CCAR1 HERC2 PIPSL CDK7	4.36e-09	212	122	10	33853758
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DHX16 COPG2 HUWE1 ECPAS BIRC6 PDIA4 XPO5 WDR6 CCAR1 DDX23 HERC2 RPL4 NIPBL HSPA9 HDAC2	1.05e-08	653	122	15	22586326
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ZMYM2 COPG2 ECPAS NDUFS2 GTF3C5 CYFIP1 AP1G1 XPO5 WDR6 TUBGCP3 LTN1 DDX23 HSPA9 HDAC2	1.17e-08	560	122	14	35241646
Pubmed	Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.	OPRL1 GRK2 GRK3	4.21e-08	3	122	3	12130708
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ATR DDX60 ECPAS CLPTM1L XPO5 LTN1 HERC2 RPL4 AP3D1	4.36e-08	202	122	9	33005030
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	COPG2 HUWE1 ECPAS GTF3C5 CDC37 CYFIP1 AP1G1 XPO5 TUBGCP3 CCAR1 RPL4 AP3D1 HSPA9 HDAC2	5.89e-08	638	122	14	33239621
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DHX16 ATR COPS3 HUWE1 PPAT ECPAS NDUFS2 GTF3C5 CYFIP2 PDIA4 CDC37 CLPTM1L CYFIP1 AP1G1 XPO5 WDR6 CCAR1 RPL4 NIPBL HSPA9	1.22e-07	1425	122	20	30948266
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX16 COPS3 HUWE1 BIRC6 GTF3C5 CDC37 CYFIP1 AP1G1 WDR6 TUBGCP3 LTN1 CCAR1 DDX23 TAF2 HERC2 RPL4 NIPBL AP3D1 HSPA9	2.61e-07	1353	122	19	29467282
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PDE4A ZMYM2 GRIA4 BCL11A HUWE1 CYFIP2 BCL11B CYFIP1 LDB1 KLHL7 CCAR1 NAV1 HERC2 NIPBL HSPA9 HDAC2	2.80e-07	963	122	16	28671696
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ATG2B ZMYM2 COPG2 HUWE1 ECPAS BIRC6 GTF3C5 WDR6 BRD4 NAV1 HDAC2	2.82e-07	418	122	11	34709266
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	COPG2 COPS3 HUWE1 PPAT ECPAS GTF3C5 PDIA4 CDC37 CLPTM1L AP1G1 XPO5 RPL4 HSPA9 EPB41 HDAC2	4.80e-07	878	122	15	37223481
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	DHX16 HDHD5 COPG2 HUWE1 BIRC6 GTF3C5 CDC37 CYFIP1 AP1G1 LTN1 CCAR1 NIPBL AP3D1	1.25e-06	704	122	13	29955894
Pubmed	Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice.	CYFIP2 BCL11B CYFIP1	1.46e-06	7	122	3	30687000
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZMYM2 COPS3 BCL11A PPAT ECPAS PDIA4 XPO5 BRD4 TUBGCP3 CCAR1 DDX23 ZNF770 NIPBL HSPA9 HDAC2 CDK7	1.66e-06	1103	122	16	34189442
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	COPG2 HUWE1 ECPAS BIRC6 NDUFS2 CDC37 CLPTM1L XPO5 TUBGCP3 LTN1 PTRH2 HERC2	3.66e-06	657	122	12	36180527
Pubmed	BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter.	BCL11A BCL11B HDAC2	4.96e-06	10	122	3	16091750
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ZMYM2 COPS3 HUWE1 GTF3C5 BCL11B LDB1 CCAR1 RPL4 HSPA9 EPB41 HDAC2	7.01e-06	583	122	11	29844126
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ATG2B COPG2 ECPAS NDUFS2 PDIA4 CLPTM1L CYFIP1 XPO5 RPL4 AP3D1 HSPA9 EPB41	7.79e-06	708	122	12	39231216
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	PPAT NDUFS2 CYFIP2 PDIA4 CYFIP1 ADAMTS20 DDX23 PIPSL RPL4 NIPBL AP3D1 HSPA9 HDAC2	9.26e-06	847	122	13	35235311
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	ATR HDHD5 HUWE1 ECPAS NDUFS2 TUBGCP3 CCAR1 AP3D1 HSPA9	1.15e-05	396	122	9	26687479
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	HDHD5 DDX60 COPG2 COPS3 HUWE1 MAP7 ECPAS NDUFS2 CDC37 CLPTM1L LDB1 XPO5 WDR6 LTN1 PTRH2 DDX23 AP3D1	1.18e-05	1440	122	17	30833792
Pubmed	Mice lacking glutamate carboxypeptidase II develop normally, but are less susceptible to traumatic brain injury.	FOLH1 FOLH1B	1.22e-05	2	122	2	25872793
Pubmed	Glutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury.	FOLH1 FOLH1B	1.22e-05	2	122	2	27091009
Pubmed	COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein.	BCL11A BCL11B	1.22e-05	2	122	2	12196208
Pubmed	Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.	CYFIP2 CYFIP1	1.22e-05	2	122	2	38128786
Pubmed	Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen.	FOLH1 FOLH1B	1.22e-05	2	122	2	8417812
Pubmed	Expression pattern of mouse homolog of prostate-specific membrane antigen (FOLH1) in the transgenic adenocarcinoma of the mouse prostate model.	FOLH1 FOLH1B	1.22e-05	2	122	2	12712410
Pubmed	NLRP7, Involved in Hydatidiform Molar Pregnancy (HYDM1), Interacts with the Transcriptional Repressor ZBTB16.	ZBTB16 NLRP7	1.22e-05	2	122	2	26121690
Pubmed	MidA is a putative methyltransferase that is required for mitochondrial complex I function.	NDUFS2 NDUFAF7	1.22e-05	2	122	2	20406883
Pubmed	BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange-like syndrome.	BRD4 NIPBL	1.22e-05	2	122	2	29379197
Pubmed	Comparative analysis of prostate-specific membrane antigen (PSMA) versus a prostate-specific membrane antigen-like gene.	FOLH1 FOLH1B	1.22e-05	2	122	2	14716746
Pubmed	Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.	GRK2 GRK3	1.22e-05	2	122	2	10198406
Pubmed	Detailed genetic mapping around a putative prostate-specific membrane antigen locus on human chromosome 11p11.2.	FOLH1 FOLH1B	1.22e-05	2	122	2	9691167
Pubmed	The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes.	BRD4 NIPBL	1.22e-05	2	122	2	31320616
Pubmed	CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis.	BCL11A BCL11B	1.22e-05	2	122	2	15465497
Pubmed	Combinational therapeutic targeting of BRD4 and CDK7 synergistically induces anticancer effects in head and neck squamous cell carcinoma.	BRD4 CDK7	1.22e-05	2	122	2	31765738
Pubmed	G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.	GRK2 GRK3	1.22e-05	2	122	2	11762794
Pubmed	Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis.	FOLH1 FOLH1B	1.22e-05	2	122	2	23169655
Pubmed	Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism.	CYFIP2 CYFIP1	1.22e-05	2	122	2	29752658
Pubmed	Glutamate carboxypeptidase II and folate deficiencies result in reciprocal protection against cognitive and social deficits in mice: implications for neurodevelopmental disorders.	FOLH1 FOLH1B	1.22e-05	2	122	2	22076974
Pubmed	NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I.	NDUFS2 NDUFAF7	1.22e-05	2	122	2	24089531
Pubmed	Cloning, expression, genomic localization, and enzymatic activities of the mouse homolog of prostate-specific membrane antigen/NAALADase/folate hydrolase.	FOLH1 FOLH1B	1.22e-05	2	122	2	11210180
Pubmed	Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injury.	FOLH1 FOLH1B	1.22e-05	2	122	2	16190866
Pubmed	Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II.	FOLH1 FOLH1B	1.22e-05	2	122	2	19347959
Pubmed	Cloning of GRK2 cDNA from S49 murine lymphoma cells.	GRK2 GRK3	1.22e-05	2	122	2	8638670
Pubmed	Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate.	FOLH1 FOLH1B	1.22e-05	2	122	2	12358725
Pubmed	Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma.	FOLH1 TUBGCP3	1.22e-05	2	122	2	26079448
Pubmed	Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.	GRK2 GRK3	1.22e-05	2	122	2	33060647
Pubmed	GCPII Inhibition Promotes Remyelination after Peripheral Nerve Injury in Aged Mice.	FOLH1 FOLH1B	1.22e-05	2	122	2	39000003
Pubmed	G protein--coupled receptor kinases.	GRK2 GRK3	1.22e-05	2	122	2	8035170
Pubmed	C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.	CYFIP2 CYFIP1	1.22e-05	2	122	2	24357318
Pubmed	A novel PSMA/GCPII-deficient mouse model shows enlarged seminal vesicles upon aging.	FOLH1 FOLH1B	1.22e-05	2	122	2	30256431
Pubmed	Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction.	FOLH1 FOLH1B	1.22e-05	2	122	2	16809768
Pubmed	Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla 1H-MRS study.	FOLH1 FOLH1B	1.22e-05	2	122	2	30458729
Pubmed	The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.	BCL11A BCL11B	1.22e-05	2	122	2	11719382
Pubmed	Molecular cloning and characterization of the protein 4.1O gene, a novel member of the protein 4.1 family with focal expression in ovary.	EPB41 FRMD3	1.22e-05	2	122	2	12601556
Pubmed	Cytoplasmic FMR1 interacting protein (CYFIP) family members and their function in neural development and disorders.	CYFIP2 CYFIP1	1.22e-05	2	122	2	34327661
Pubmed	Distinguishing Plasmodium falciparum treatment failures from reinfections by restrictions fragment length polymorphism and polymerase chain reaction genotyping.	FOLH1 FOLH1B	1.22e-05	2	122	2	9347959
Pubmed	Early embryonic death of glutamate carboxypeptidase II (NAALADase) homozygous mutants.	FOLH1 FOLH1B	1.22e-05	2	122	2	14556233
Pubmed	Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion.	CYFIP2 CYFIP1	1.22e-05	2	122	2	35567753
Pubmed	Mapping, genomic organization and promoter analysis of the human prostate-specific membrane antigen gene.	FOLH1 FOLH1B	1.22e-05	2	122	2	9838072
Pubmed	The Rho exchange factor Net1 is regulated by nuclear sequestration.	NET1 ARHGEF3	1.22e-05	2	122	2	11839749
Pubmed	Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.	CYFIP2 CYFIP1	1.22e-05	2	122	2	31324746
Pubmed	A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression.	GRK3 HDAC2	1.22e-05	2	122	2	37543278
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	COPG2 COPS3 HUWE1 MAP7 ECPAS GTF3C5 CYFIP2 PDIA4 CDC37 CYFIP1 XPO5 RPL4 AP3D1 HSPA9 HDAC2	1.26e-05	1149	122	15	35446349
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	DHX16 MAP7 BIRC6 PDIA4 CDC37 CLPTM1L CYFIP1 XPO5 PIK3C3 WDR6 CCAR1 RPL4 NIPBL AP3D1 HSPA9 CDK7	1.28e-05	1297	122	16	33545068
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ZBTB16 COPG2 MAP7 ECPAS PDIA4 BRD4 TUBGCP3 LTN1 CCAR1 HERC2 HDAC2 EIF4E2	1.46e-05	754	122	12	33060197
Pubmed	Defining the membrane proteome of NK cells.	HUWE1 ECPAS BIRC6 CYFIP2 CLPTM1L GRK2 AGO4 AP1G1 PIK3C3 PLXNC1 TUBGCP3 PTRH2 HERC2 RPL4 AP3D1	1.53e-05	1168	122	15	19946888
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	HDHD5 ATG2B HUWE1 PPAT BIRC6 NDUFS2 PDIA4 CDC37 CLPTM1L RPUSD4 WDR6 NDUFAF7 PTRH2 NAV1 HERC2 RPL4 HSPA9	1.93e-05	1496	122	17	32877691
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NET1 ZMYM2 COPG2 MAP7 NDUFS2 CYFIP2 CLPTM1L CYFIP1 AP1G1 LTN1 PTRH2 CCAR1 TAF2 HERC2 NIPBL EPB41 CDK7	1.94e-05	1497	122	17	31527615
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DHX16 ZMYM2 NDUFS2 GTF3C5 SULF2 BRD4 TUBGCP3 CCAR1 DDX23 SRPX RPL4 NIPBL AP3D1 HDAC2	2.77e-05	1082	122	14	38697112
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	ZMYM2 BCL11A BCL11B BRD4 HDAC2	3.25e-05	103	122	5	32744500
Pubmed	Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.	GRK2 GRK3	3.65e-05	3	122	2	10754297
Pubmed	Prostate specific membrane antigen (PSMA) regulates angiogenesis independently of VEGF during ocular neovascularization.	FOLH1 FOLH1B	3.65e-05	3	122	2	22815987
Pubmed	Deletion of glutamate carboxypeptidase II (GCPII), but not GCPIII, provided long-term benefits in mice with traumatic brain injury.	FOLH1 FOLH1B	3.65e-05	3	122	2	37349952
Pubmed	Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.	GRK2 GRK3	3.65e-05	3	122	2	10085131
Pubmed	Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.	GRK2 GRK3	3.65e-05	3	122	2	7761854
Pubmed	The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.	GRK2 GRK3	3.65e-05	3	122	2	31604529
Pubmed	Biochemical characterization of human glutamate carboxypeptidase III.	FOLH1 FOLH1B	3.65e-05	3	122	2	17241121
Pubmed	Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair.	ATR HERC2	3.65e-05	3	122	2	23178497
Pubmed	Molecular evolution of the transferrin receptor/glutamate carboxypeptidase II family.	FOLH1 FOLH1B	3.65e-05	3	122	2	17160644
Pubmed	HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies.	BRD4 HDAC2	3.65e-05	3	122	2	30463877
Pubmed	Parallel Metabolomics and Lipidomics of a PSMA/GCPII Deficient Mouse Model Reveal Alteration of NAAG Levels and Brain Lipid Composition.	FOLH1 FOLH1B	3.65e-05	3	122	2	38377674
Pubmed	Molecular identification of β-citrylglutamate hydrolase as glutamate carboxypeptidase 3.	FOLH1 FOLH1B	3.65e-05	3	122	2	21908619
Pubmed	Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK.	SNRK HDAC2	3.65e-05	3	122	2	36640195
Pubmed	Regulation of pulmonary fibrosis by chemokine receptor CXCR3.	BCL11A BCL11B	3.65e-05	3	122	2	15254596
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HDHD5 HUWE1 MAP7 BIRC6 NDUFS2 CYFIP1 AP1G1 PTRH2 NAV1 DDX23 RPL4 NIPBL AP3D1 HSPA9 HDAC2 EIF4E2	3.67e-05	1415	122	16	28515276
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF6 C5orf22 NET1 BCL11A MAP7 BCL11B SULF2 WDR6 BRD4 TUBGCP3 LTN1 PIP4K2B TAF2 HDAC2	3.87e-05	1116	122	14	31753913
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	C5orf22 HUWE1 ECPAS PDIA4 CDC37 CYFIP1 XPO5 WDR6 LTN1 PTRH2 DUSP10 PIPSL RPL4	3.97e-05	974	122	13	28675297
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ATR COPG2 COPS3 HUWE1 MAP7 XPO5 BRD4 TUBGCP3 DDX23 NIPBL	4.11e-05	582	122	10	20467437
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	SNRK COPG2 COPS3 ECPAS DEGS1 PDIA4 CDC37 XPO5 PIK3C3 CCNA1 DDX23 PIP5K1B HERC2 EPB41 EIF4E2	4.54e-05	1284	122	15	17353931
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZBTB16 ZMYM2 HUWE1 NEDD9 LDB1 AP1G1 XPO5 BRD4 PLAGL1 HERC2	4.67e-05	591	122	10	15231748
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ATG2B GRIA4 SNRK CPZ HUWE1 BIRC6 NDUFS2 GRK2 NAV1 PIP4K2B HSPA9 EPB41 SHISA6 HDAC2	4.82e-05	1139	122	14	36417873
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	DHX16 DCAF6 ZMYM2 COPS3 GTF3C5 PDIA4 NDUFAF7 TUBGCP3 CCAR1 DDX23 HERC2 NIPBL PLK4 HDAC2	5.60e-05	1155	122	14	20360068
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	COPS3 HUWE1 MAP7 BIRC6 NDUFS2 WDR6 TAF2 HERC2 HDAC2 EIF4E2	5.60e-05	604	122	10	38803224
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	DHX16 ERICH1 ZMYM2 GTF3C5 BRD4 ZNF770 TAF2 HERC2 NIPBL HDAC2	5.92e-05	608	122	10	36089195
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	DHX16 ATR ECPAS GTF3C5 CDC37 XPO5 BRD4 CCAR1 DDX23 TAF2 NIPBL HDAC2 CDK7	5.97e-05	1014	122	13	32416067
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	COPG2 ECPAS XPO5 WDR6 PIP5K1B HERC2 RPL4 HSPA9	6.50e-05	383	122	8	29331416
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	DCAF6 COPS3 HUWE1 PDIA4 CDC37 RPL4 HSPA9 EPB41 HDAC2	6.56e-05	495	122	9	28581483
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	HUWE1 CDC37 RPUSD4 CYFIP1 PIK3C3 NDUFAF7 PIPSL HDAC2 LARGE1	6.67e-05	496	122	9	31343991
Interaction	SIRT7 interactions	DHX16 ATR COPG2 HUWE1 ECPAS BIRC6 PDIA4 XPO5 WDR6 BRD4 CCAR1 DDX23 HERC2 RPL4 NIPBL HSPA9 HDAC2	1.39e-06	744	117	17	int:SIRT7
Interaction	HDGFL2 interactions	C3orf20 DEGS1 PDIA4 BRD4 DDX23 PIP4K2B TAF2 RPL4 CDK7	1.99e-06	194	117	9	int:HDGFL2
Interaction	LRRC31 interactions	ATR DDX60 ECPAS CLPTM1L XPO5 LTN1 HERC2 RPL4 AP3D1	3.13e-06	205	117	9	int:LRRC31
Interaction	C9orf78 interactions	ZMYM2 COPG2 ECPAS NDUFS2 GTF3C5 CYFIP1 AP1G1 XPO5 WDR6 TUBGCP3 LTN1 DDX23 HSPA9 HDAC2	1.46e-05	620	117	14	int:C9orf78
Interaction	ARRDC2 interactions	HUWE1 WDR6 LTN1 PIPSL HDAC2	1.53e-05	54	117	5	int:ARRDC2
Interaction	BACC1 interactions	SLC38A5 BCL11A BCL11B BRD4 HSPA9 HDAC2	3.21e-05	104	117	6	int:BACC1
Interaction	MYH10 interactions	GRIA4 ECPAS BIRC6 PDIA4 BRD4 LTN1 DDX23 HERC2 HDAC2 CDK7	4.68e-05	359	117	10	int:MYH10
Interaction	AR interactions	DCAF6 ZBTB16 FOLH1 ZMYM2 HUWE1 ECPAS CDC37 CYFIP1 LDB1 XPO5 BRD4 CCAR1 DDX23 NIPBL HSPA9 HDAC2 CDK7	5.86e-05	992	117	17	int:AR
Interaction	MAP1LC3C interactions	BIRC6 CDC37 PIK3C3 NIPBL HSPA9	6.21e-05	72	117	5	int:MAP1LC3C
Interaction	GAS7 interactions	CYFIP2 CDC37 CYFIP1 BRD4	6.84e-05	38	117	4	int:GAS7
Interaction	NR2E1 interactions	DCAF6 ZMYM2 BCL11A HDAC2	6.84e-05	38	117	4	int:NR2E1
Coexpression	NAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP	DHX16 NET1 DDX60 CYFIP2 PDIA4 PLXNC1 LTN1 PIP4K2B HDAC2 EIF4E2	6.54e-06	367	118	10	M41159
Coexpression	DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_UP	NET1 COPS3 MAP7 PPAT DEGS1 CDC37 LDB1 PIK3C3 PLXNC1 TUBGCP3 DDX23 PIP5K1B TAF2 ARHGEF3 HSPA9 EPB41 HDAC2 EIF4E2 CDK7	1.55e-05	1399	118	19	M535
Coexpression	GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP	COPS3 NADSYN1 XPO5 WDR6 NAV1 TAF2 PLK4	2.27e-05	187	118	7	M6807
Coexpression	GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN	ERICH1 SPATA6 HDHD5 COPS3 S1PR3 GRK3 HERC2	3.28e-05	198	118	7	M6114
Coexpression	GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN	MAP7 CYFIP2 KLHL7 NAV1 DUSP10 TAF2 HDAC2	3.50e-05	200	118	7	M5096
Coexpression	BLALOCK_ALZHEIMERS_DISEASE_DN	DCAF6 ATR SNRK BCL11A NDUFS2 DEGS1 BCL11B LTN1 PTRH2 CCNA1 OSBPL10 PIP5K1B ARHGEF3 HERC2 HSPA9 CDK7 LARGE1	4.40e-05	1248	118	17	M17728
Coexpression	GSE6674_UNSTIM_VS_CPG_STIM_BCELL_UP	CALCR NET1 GCK NDUFS2 SHISA6 LARGE1	5.52e-05	147	118	6	M6918
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1	ZNF366 BCL11A RGS1 SULF2 GRK3 PLXNC1 NAV1	2.53e-07	79	116	7	GSM538265_100
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1	BCL11A RGS1 SULF2 GRK3 PLXNC1 NAV1	3.74e-06	76	116	6	GSM538248_100
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-3	BCL11A RGS1 SULF2 GRK3 PLXNC1 NAV1	3.74e-06	76	116	6	GSM538249_100
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.Sp, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Spleen, avg-1	BCL11A RGS1 SULF2 GRK3 PLXNC1 NAV1	4.03e-06	77	116	6	GSM605839_100
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2	BCL11A RGS1 SULF2 GRK3 PLXNC1 NAV1	4.35e-06	78	116	6	GSM538266_100
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.Sp, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Spleen, avg-2	BCL11A RGS1 SULF2 GRK3 PLXNC1 NAV1	5.05e-06	80	116	6	GSM605837_100
CoexpressionAtlas	Myeloid Cells, DC.IIhilang-103-11blo.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b-, Lymph Node, avg-3	NET1 RGS1 SULF2 GRK3 PLXNC1 NAV1	5.83e-06	82	116	6	GSM538277_100
CoexpressionAtlas	Myeloid Cells, DC.4+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	BCL11A RGS1 SULF2 GRK3 PLXNC1 NAV1	5.83e-06	82	116	6	GSM538242_100
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.SLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2	NET1 RGS1 SULF2 GRK3 PLXNC1 NAV1	6.25e-06	83	116	6	GSM854285_100
CoexpressionAtlas	Myeloid Cells, DC.4+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	RGS1 SULF2 GRK3 PLXNC1 NAV1	5.32e-05	74	116	5	GSM538245_100
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1	RGS1 SULF2 GRK3 PLXNC1 NAV1	5.68e-05	75	116	5	GSM605826_100
CoexpressionAtlas	Myeloid Cells, DC.IIhilang-103-11b+.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b+, Lymph Node, avg-3	NET1 RGS1 GRK3 PLXNC1 NAV1	6.85e-05	78	116	5	GSM538274_100
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.SLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-1	NET1 RGS1 GRK3 PLXNC1 NAV1	8.21e-05	81	116	5	GSM854290_100
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-1	RGS1 SULF2 GRK3 PLXNC1 LARGE1	1.15e-04	87	116	5	GSM538262_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000	BCL11A HUWE1 S1PR3 BCL11B KLHL7 ADAMTS20 FRMD3	2.67e-04	229	116	7	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Activated_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ERICH1 NET1 ZNF366 C10orf90 RGS1 GRK3 CCNA1 NAV1	3.02e-08	177	121	8	370aee11a6dc2c6f4366a13c3171f37bc5b32d65
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF366 IRAK2 BCL11A RGS1 NEDD9 SULF2 GRK3	7.82e-07	186	121	7	305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCell	Biopsy_Other_PF-Immune-pDCs\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ARPP21 NLRP7 BCL11A PLEKHD1 RGS1 CYFIP2 SULF2	1.15e-06	197	121	7	598a130eb7afb1bb95da64a964218362627feb49
ToppCell	distal-3-Hematologic-Myeloid_Dendritic_Type_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NET1 ZNF366 IRAK2 BCL11A RGS1 SULF2 NAV1	1.19e-06	198	121	7	b21227c7366ef79b36048509a91d2d35fd5e4956
ToppCell	mild-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NET1 ZNF366 BCL11A RGS1 SULF2 NAV1 PLAGL1	1.27e-06	200	121	7	86f585bf9066b179bbcbc703bf43f15da4a07284
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STYK1 ZMYM2 RGS1 BCL11B DUSP10 PLK4	3.35e-06	149	121	6	65778f19599b4955c0a16f0121237656449431fb
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARPP21 ZNF366 BCL11A CYFIP2 SULF2 GRK2	4.21e-06	155	121	6	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	Immune-dendritic_cell\|World / Lineage, Cell type, age group and donor	ZNF366 BCL11A PLEKHD1 RGS1 CYFIP2 SULF2	7.39e-06	171	121	6	6a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCell	ICU-SEP-Myeloid-pDC\|ICU-SEP / Disease, Lineage and Cell Type	ARPP21 NLRP7 BCL11A RGS1 MINAR1 SRPX	7.39e-06	171	121	6	72c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell	Children_(3_yrs)-Immune-dendritic_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF366 BCL11A PLEKHD1 RGS1 SULF2 NAV1	7.39e-06	171	121	6	6a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCell	moderate-Myeloid-pDC\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARPP21 NLRP7 BCL11A PLEKHD1 RGS1 SULF2	9.90e-06	180	121	6	a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCell	NS-moderate-d_16-33-Myeloid-pDC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARPP21 NLRP7 BCL11A PLEKHD1 RGS1 SULF2	9.90e-06	180	121	6	144818e69613296cde43f29cb8c20899c670b319
ToppCell	10x5'-Lung-Myeloid_Dendritic-migDC\|Lung / Manually curated celltypes from each tissue	NET1 ZNF366 BCL11A SULF2 CCNA1 NAV1	9.90e-06	180	121	6	e9e8992deb0beeee5548910e4616e7c990763d99
ToppCell	COVID-19-APC-like-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	ZNF366 BCL11A RGS1 SULF2 GRK3 NAV1	1.09e-05	183	121	6	703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCell	COVID-19-APC-like\|COVID-19 / group, cell type (main and fine annotations)	ZNF366 BCL11A RGS1 SULF2 GRK3 NAV1	1.09e-05	183	121	6	b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCell	IPF-Myeloid-DC_Mature\|World / Disease state, Lineage and Cell class	ERICH1 NET1 RGS1 SULF2 GRK3 NAV1	1.19e-05	186	121	6	d0d3953d9b199e0e792990b8551efb993393fe7e
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARPP21 NLRP7 BCL11A PLEKHD1 CYFIP2 SULF2	1.19e-05	186	121	6	0096a61b1841784c913752b4f3639200446cc02c
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARPP21 NLRP7 BCL11A PLEKHD1 CYFIP2 SULF2	1.19e-05	186	121	6	6345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARPP21 NLRP7 BCL11A PLEKHD1 CYFIP2 SULF2	1.19e-05	186	121	6	9e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NET1 ZNF366 IRAK2 BCL11A RGS1 SULF2	1.27e-05	188	121	6	d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CPA6 LYPD6B COPG2 MAP7 OSBPL10 PIP5K1B	1.27e-05	188	121	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	(3)_DC_activated\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ERICH1 ZNF366 BCL11A RGS1 SULF2 NAV1	1.31e-05	189	121	6	e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCell	normal_Lymph_Node-Myeloid_cells-Activated_DCs\|normal_Lymph_Node / Location, Cell class and cell subclass	ERICH1 NET1 ZNF366 GRK3 PLXNC1 NAV1	1.35e-05	190	121	6	15978ddd37b521343f88b62dad1643077fc22b2b
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	IRAK2 RGS1 SULF2 GRK2 PLXNC1 NAV1	1.39e-05	191	121	6	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	NET1 ZNF366 IRAK2 BCL11A RGS1 SULF2	1.39e-05	191	121	6	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LYPD6B MAP7 CYFIP2 AGBL4 PIP5K1B FRMD3	1.43e-05	192	121	6	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	10x5'-Lung-Myeloid_Dendritic\|Lung / Manually curated celltypes from each tissue	NET1 ZNF366 BCL11A RGS1 SULF2 NAV1	1.47e-05	193	121	6	7bce609699c515d2d114596a0c527f90cc09c4af
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NET1 ZNF366 BCL11A MAP7 SULF2 NAV1	1.51e-05	194	121	6	b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NET1 ZNF366 BCL11A MAP7 SULF2 NAV1	1.51e-05	194	121	6	2210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE4A IRAK2 BCL11A RGS1 SULF2 RPL4	1.51e-05	194	121	6	bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	NLRP7 ZNF366 BCL11A PLEKHD1 SULF2 SRPX	1.51e-05	194	121	6	768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCell	390C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ERICH1 NET1 ZNF366 BCL11A SULF2 NAV1	1.56e-05	195	121	6	ecf7d9856a5b507ec17c325c9a772dc5a184bc8e
ToppCell	healthy_donor-Myeloid-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	NET1 ZNF366 RGS1 CYFIP1 SULF2 NAV1	1.61e-05	196	121	6	ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCell	healthy_donor-Myeloid-Dendritic-cDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	NET1 ZNF366 RGS1 CYFIP1 SULF2 NAV1	1.61e-05	196	121	6	aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCell	COVID-19-Myeloid-Migratory_DC\|COVID-19 / Condition, Lineage and Cell class	NET1 ZNF366 BCL11A RGS1 SULF2 NAV1	1.65e-05	197	121	6	b6d6cdae33753c1e38394f1f879e00b87f9c0496
ToppCell	Biopsy_IPF-Immune-pDCs\|Biopsy_IPF / Sample group, Lineage and Cell type	ARPP21 NLRP7 BCL11A PLEKHD1 RGS1 SULF2	1.70e-05	198	121	6	aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCell	Sepsis-ICU-SEP-Myeloid-pDC\|ICU-SEP / Disease, condition lineage and cell class	LYPD6B NLRP7 BCL11A PLEKHD1 RGS1 MINAR1	1.70e-05	198	121	6	fe8a68bff8c1b9566eee4bfcab564f206a20ae7b
ToppCell	COVID-19-Myeloid-Migratory_DC\|Myeloid / Condition, Lineage and Cell class	NET1 ZNF366 BCL11A RGS1 SULF2 NAV1	1.70e-05	198	121	6	90f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCell	distal-2-Hematologic-Plasmacytoid_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ARPP21 NLRP7 BCL11A RGS1 CYFIP2 SULF2	1.75e-05	199	121	6	78796b05d28b35e7361b6271d4a3858faa39c45c
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARPP21 NET1 ZNF366 IRAK2 RGS1 SULF2	1.75e-05	199	121	6	26ea06960e8ea061a71756750b84489609f78162
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ARPP21 NLRP7 BCL11A RGS1 CYFIP2 SULF2	1.80e-05	200	121	6	ef42753c9fbe3770e3f415cd7ab412654d359edb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	ARPP21 BCL11A NEDD9 BCL11B RPL4 HDAC2	1.80e-05	200	121	6	19055194a5e0ea122f1b8fc62df44813f6843c95
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LYPD6B IL17F S1PR3 CCNA1 SHISA6	2.73e-05	129	121	5	f83187c0bb06528127b8d2d56674ab1946846951
ToppCell	Control-Myeloid-Dendritic_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 GCK PLEKHD1 RGS1 SULF2	4.47e-05	143	121	5	bb8d4c335682d1a6798bed0de8bb0603054a4944
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF366 BCL11A PLEKHD1 SULF2 NAV1	5.98e-05	152	121	5	0769857f25da2e6169420818e61d65e33b7277b1
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 BCL11A PLEKHD1 RGS1 SULF2	6.16e-05	153	121	5	c81a88d3f707487c511020d3960a1c41e706c6a0
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	SLC38A5 S1PR3 PLXNC1 DENND6B CDK7	7.39e-05	159	121	5	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LYPD6B ANO5 S1PR3 CCNA1 SHISA6	7.62e-05	160	121	5	0bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LYPD6B ANO5 CCNA1 DUSP10 SHISA6	7.84e-05	161	121	5	bf70be1de418615b5442ec684552551edaf1f072
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF366 BCL11A RGS1 SULF2 NAV1	7.84e-05	161	121	5	cd41abb7ae659d3d314281783a0aaad562b26037
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARPP21 ZNF366 BCL11A PLEKHD1 SULF2	8.08e-05	162	121	5	86a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_1\|COVID-19_Mild / Disease condition and Cell class	HDHD5 CPZ ECPAS GRK2 GRK3	8.81e-05	165	121	5	ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARPP21 BCL11A PLEKHD1 RGS1 SULF2	8.81e-05	165	121	5	e2a70dd5870fe8708bf630ed3e6eb3f295df0cdf
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|356C / Donor, Lineage, Cell class and subclass (all cells)	ERICH1 NET1 ZNF366 GRK3 NAV1	9.32e-05	167	121	5	43a9375fdbafd7450c553e4620e21537e08639dd
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ECPAS PLEKHD1 DUSP10 SHISA6 FRMD3	9.32e-05	167	121	5	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NLRP7 STYK1 SLC38A5 RGS1 BCL11B	9.32e-05	167	121	5	abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ECPAS PLEKHD1 DUSP10 SHISA6 FRMD3	9.32e-05	167	121	5	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	(3)_DC_plasmacytoid\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	NLRP7 BCL11A PLEKHD1 RGS1 SULF2	9.59e-05	168	121	5	8a913db9b2a1a4ff96fb139734a3834e6aa263f1
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RGSL1 CALCR STYK1 CCDC83	9.75e-05	88	121	4	2075743c7c0b6d74e80464a6bc776206d744d502
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RGSL1 CALCR STYK1 CCDC83	9.75e-05	88	121	4	a49319bc97188550e08248973e10c626124c3917
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RGSL1 CALCR STYK1 CCDC83	9.75e-05	88	121	4	14b11249a2b3fa327622897fe74630c2697ea47e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE4A ZBTB16 NLRP7 STYK1 NEDD9	9.86e-05	169	121	5	e7470a5b060881b2a8ce2ab04b0788396aa13889
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGSL1 ARPP21 ATR SLC25A26 S1PR3	1.01e-04	170	121	5	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLRP7 BCL11A RGS1 CYFIP2 SULF2	1.01e-04	170	121	5	b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARPP21 NLRP7 BCL11A RGS1 SULF2	1.01e-04	170	121	5	92e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARPP21 NLRP7 BCL11A RGS1 SULF2	1.01e-04	170	121	5	9f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell	droplet-Fat-Mat-18m-Hematologic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGSL1 SLC38A5 XPO5 PIP5K1B	1.02e-04	89	121	4	56039e126e6f3e8fcaf3c47237c980e514512536
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	ERICH1 NET1 ZNF366 C10orf90 CCNA1	1.04e-04	171	121	5	ce290930385cac35dbd21a5e91cf0f93cf3e99f8
ToppCell	wk_15-18-Hematologic-Myeloid-pDC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NLRP7 BCL11A PLEKHD1 RGS1 SULF2	1.10e-04	173	121	5	b571970e3ba88afc07041c5692ccfd85fc39e796
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NET1 ZNF366 BCL11A SULF2 NAV1	1.13e-04	174	121	5	991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NET1 ZNF366 BCL11A SULF2 NAV1	1.13e-04	174	121	5	c8cec89369cf3896c5626e447051e76a142cb6df
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ARPP21 BCL11A PLEKHD1 CYFIP2 SULF2	1.13e-04	174	121	5	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	facs-Kidney-nan-18m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STYK1 IL17F RGS1 BCL11B DUSP10	1.16e-04	175	121	5	84d91843b34504636d5af6bda9930031409a1627
ToppCell	facs-Kidney-nan-18m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STYK1 IL17F RGS1 BCL11B DUSP10	1.16e-04	175	121	5	2368aa8318ab83e0e0fd539a17264f9e1d755cf1
ToppCell	Adult-Immune-dendritic_cell-D175\|Adult / Lineage, Cell type, age group and donor	ZNF366 IRAK2 RGS1 SULF2 NAV1	1.19e-04	176	121	5	1f0f1f953e6d61119f342de0d980aa1287511dba
ToppCell	Dendritic_Cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ZNF366 BCL11A SULF2 PLXNC1 NAV1	1.22e-04	177	121	5	d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO1 PLEKHD1 BCL11B SULF2 DUSP10	1.22e-04	177	121	5	4d67e24653caa318039870114849426ff2582e0c
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARPP21 ZNF366 BCL11A PLEKHD1 SULF2	1.22e-04	177	121	5	c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCell	COPD-Myeloid-pDC\|COPD / Disease state, Lineage and Cell class	ARPP21 BCL11A PLEKHD1 CYFIP2 SULF2	1.22e-04	177	121	5	415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell	IPF-Myeloid-pDC\|IPF / Disease state, Lineage and Cell class	ARPP21 BCL11A PLEKHD1 CYFIP2 SULF2	1.26e-04	178	121	5	8d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell	NS-critical-LOC-Lymphoid-PC\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NLRP7 SLC38A5 PDIA4 CLPTM1L DENND6B	1.29e-04	179	121	5	c044478525b8e7eedecddb924c1b049331180cb2
ToppCell	COPD-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	ARPP21 BCL11A PLEKHD1 CYFIP2 SULF2	1.29e-04	179	121	5	29b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL17F RGS1 CYFIP2 BCL11B SNAPC1	1.32e-04	180	121	5	5fdd10ffdf49f0e818f865ca095a3882b35c640e
ToppCell	B_cells-Naive_B_cells_\|World / Immune cells in Kidney/Urine in Lupus Nephritis	BCL11A GRK3 OSBPL10 PIP5K1B LARGE1	1.39e-04	182	121	5	63c3b63315276b66667d49fab09661ac320e7a36
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CPA6 LYPD6B BCL11A NEDD9 SHISA6	1.39e-04	182	121	5	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	Control-APC-like-Dendritic_cells\|Control / group, cell type (main and fine annotations)	ZNF366 RGS1 SULF2 PLXNC1 NAV1	1.43e-04	183	121	5	8f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCell	Control-APC-like\|Control / group, cell type (main and fine annotations)	ZNF366 RGS1 SULF2 PLXNC1 NAV1	1.43e-04	183	121	5	c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LYPD6B ANO1 BCL11B PIP5K1B DUSP10	1.47e-04	184	121	5	2ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	NET1 ZNF366 IRAK2 BCL11A SULF2	1.47e-04	184	121	5	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	NLRP7 BCL11A PLEKHD1 SULF2 SRPX	1.47e-04	184	121	5	2817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCell	10x5'-GI_small-bowel-Myeloid_Dendritic-DC1\|GI_small-bowel / Manually curated celltypes from each tissue	LYPD6B NET1 ZNF366 SULF2 NAV1	1.51e-04	185	121	5	23ffba9216729b5bdb30b35742ba2627bb1200bf
ToppCell	control-Myeloid-pDC\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ARPP21 NLRP7 BCL11A PLEKHD1 SRPX	1.54e-04	186	121	5	fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCAF6 ARPP21 STYK1 AGBL4 ARHGEF3	1.54e-04	186	121	5	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	NET1 ZNF366 IRAK2 BCL11A SULF2	1.54e-04	186	121	5	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	COVID_vent-Myeloid-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ZNF366 BCL11A RGS1 SULF2 NAV1	1.54e-04	186	121	5	63a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell	normal_Lung-Myeloid_cells-Activated_DCs\|normal_Lung / Location, Cell class and cell subclass	ERICH1 NET1 RGS1 GRK3 NAV1	1.54e-04	186	121	5	0987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCell	COVID_vent-Myeloid-Dendritic-cDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ZNF366 BCL11A RGS1 SULF2 NAV1	1.54e-04	186	121	5	39457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell	normal_Lung-Myeloid_cells-CD141+_DCs\|normal_Lung / Location, Cell class and cell subclass	NET1 ZNF366 IRAK2 SULF2 NAV1	1.54e-04	186	121	5	a6698a2f4edd81b67e06531ede0e207dd0309205
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	NET1 IRAK2 BCL11A RGS1 SULF2	1.54e-04	186	121	5	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	NET1 IRAK2 BCL11A RGS1 SULF2	1.54e-04	186	121	5	b05c394aa3573ba855abc3066739ca193883b0c3
Disease	chromosome 15q11.2 deletion syndrome (implicated_via_orthology)	CYFIP2 CYFIP1	4.74e-05	3	118	2	DOID:0060393 (implicated_via_orthology)
Disease	type 2 diabetes mellitus (implicated_via_orthology)	GCK BCL11A BCL11B ADAMTS20 CDK7	6.59e-05	105	118	5	DOID:9352 (implicated_via_orthology)
Disease	Congenital muscular hypertrophy-cerebral syndrome	BRD4 NIPBL	1.57e-04	5	118	2	C1802395
Disease	Cornelia de Lange Syndrome 3	BRD4 NIPBL	1.57e-04	5	118	2	C1853099
Disease	Cornelia de Lange Syndrome 1	BRD4 NIPBL	1.57e-04	5	118	2	C4551851
Disease	De Lange syndrome	BRD4 NIPBL	2.35e-04	6	118	2	cv:C0270972
Disease	diastolic blood pressure, systolic blood pressure	ANO1 COPS3 GCK AGBL4 BCL11B PLXNC1 BRD4 NAV1 FOLH1B TAF2	3.68e-04	670	118	10	EFO_0006335, EFO_0006336
Disease	Cornelia De Lange Syndrome	BRD4 NIPBL	4.37e-04	8	118	2	C0270972
Disease	bacterial pneumonia (is_marker_for)	SFTPD GRK2	5.60e-04	9	118	2	DOID:874 (is_marker_for)
Disease	executive function measurement	BCL11A NEDD9 BCL11B XPO5 CCNA1 OSBPL10 NAV1	8.11e-04	376	118	7	EFO_0009332
Disease	airway wall thickness measurement	C10orf90 BCL11B	1.02e-03	12	118	2	EFO_0006898
Disease	Myeloproliferative disease	ATG2B ZMYM2	1.02e-03	12	118	2	C0027022
Disease	Replication Error Phenotype	XPO5 HDAC2	1.61e-03	15	118	2	C1721098
Disease	Microsatellite Instability	XPO5 HDAC2	1.61e-03	15	118	2	C0920269
Disease	puberty onset measurement	ECPAS BIRC6 CYFIP2 HERC2	1.62e-03	125	118	4	EFO_0005677
Disease	autism spectrum disorder (is_implicated_in)	BCL11A CYFIP1	1.83e-03	16	118	2	DOID:0060041 (is_implicated_in)
Disease	ovarian carcinoma	SPATA6 BCL11A RGS1 RPUSD4 OSBPL10 DUSP10	1.88e-03	321	118	6	EFO_0001075
Disease	neuroticism measurement, cognitive function measurement	BCL11A BIRC6 NEDD9 BCL11B CCNA1 OSBPL10 NAV1 SHISA6	2.02e-03	566	118	8	EFO_0007660, EFO_0008354
Disease	hyperglycemia (implicated_via_orthology)	GCK GRK2	2.07e-03	17	118	2	DOID:4195 (implicated_via_orthology)
Disease	pulmonary surfactant-associated protein d measurement	SFTPD ARHGEF3	2.33e-03	18	118	2	EFO_0020693
Disease	Myeloid Leukemia	ATG2B HDAC2	2.33e-03	18	118	2	C0023470
Disease	Leukemia, Monocytic, Chronic	ATG2B HDAC2	2.33e-03	18	118	2	C0023466
Disease	neurodegenerative disease (implicated_via_orthology)	GRIA4 BCL11A DEGS1 BCL11B	2.78e-03	145	118	4	DOID:1289 (implicated_via_orthology)
Disease	temporal lobe epilepsy (is_marker_for)	CYFIP1 HDAC2	2.87e-03	20	118	2	DOID:3328 (is_marker_for)
Disease	hemorrhoid	ANO1 BIRC6 C3orf20 SRPX	2.92e-03	147	118	4	EFO_0009552
Disease	Prostatic Neoplasms	DCAF6 ZBTB16 ATR FOLH1 DEGS1 CLPTM1L BRD4 PTRH2	3.39e-03	616	118	8	C0033578
Disease	Malignant neoplasm of prostate	DCAF6 ZBTB16 ATR FOLH1 DEGS1 CLPTM1L BRD4 PTRH2	3.39e-03	616	118	8	C0376358
Disease	Seckel syndrome	ATR PLK4	3.48e-03	22	118	2	C0265202
Disease	Primary microcephaly	TUBGCP3 PLK4	3.48e-03	22	118	2	C0431350
Disease	waist-hip ratio	ARPP21 CALCR BCL11A BIRC6 OPRL1 NEDD9 AGBL4 ADAMTS20 PIP4K2B PIPSL AP3D1 SHISA6	3.73e-03	1226	118	12	EFO_0004343
Disease	schizophrenia (is_implicated_in)	GRIA4 BCL11A CYFIP1	3.81e-03	78	118	3	DOID:5419 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
MLPSDVSILYHMKTL	ERICH1	381	Q86X53
KVMELHKSYRSMTPA	EPB41	366	P11171
VSYLMAMEKSKATPA	GRK3	11	P35626
KAYHDPMLKLSIMTE	ARHGEF3	146	Q9NR81
HRKLNAVTKEMEPYM	ANO5	436	Q75V66
KASTVHMMLQPILTY	BIRC6	3046	Q9NR09
TPAMAVSHIMLESYK	COPS3	211	Q9UNS2
VMATKMAALHYPSTT	NEDD9	791	Q14511
HPMDMSTIKSKLEAR	BRD4	396	O60885
HMYLKAVKATMILVP	CALCR	336	P30988
ADHLYSAKVMLMASP	CCAR1	441	Q8IX12
MVYKGHRNSRTMIKE	DCAF6	711	Q58WW2
DSVEPMFKHLKMTYV	AGO4	491	Q9HCK5
DPMLSKMILASEKYS	DHX16	821	O60231
LEHYMASLMPLQKSI	DENND6B	431	Q8NEG7
TYKSDPAMRKMLNHL	CPA6	216	Q8N4T0
KKFPQMSSYQRMLVH	ARPP21	186	Q9UBL0
YCSKEMPRKAHSNML	ATG2B	1666	Q96BY7
EMKVTKYHVMAPALS	ADAMTS20	421	P59510
DVRSPESHITYKMMK	CCDC83	396	Q8IWF9
VSYLMAMEKSKATPA	GRK2	11	P25098
IMTLMSHTKPYIRKK	AP3D1	151	O14617
KAYLRSMIPHLESGM	RGS1	51	Q08116
VKTKHQMYSIPEDAM	GCK	101	P35557
SVYHMTLKDLPAMVR	LTN1	1566	O94822
ARKAYHDPMLKLSIM	NET1	196	Q7Z628
KKYDHMRSALLERMP	AP1G1	571	O43747
NRMYLTPSEKHMLLK	CYFIP1	251	Q7L576
VMYMAPKSSHSQERR	OR2A12	256	Q8NGT7
LRNVAMKHISTPYMF	LARGE1	546	O95461
IKTTMRYHLTPVRMA	nan	1106	O00370
IIMPYKAAHSRNSMD	MAP7	256	Q14244
PMQELMSRHKTYSLS	LDB1	251	Q86U70
AHLCPVNKRSKYTMM	IRAK2	356	O43187
KYTMMKTHLLRTSAA	IRAK2	366	O43187
HRLKMIVDPADSSYM	HERC2	2831	O95714
IYSISMKHPQEMKTY	FOLH1	611	Q04609
MKHPQEMKTYSVSFD	FOLH1	616	Q04609
KMPFSVYSTLEKHMK	BCL11A	806	Q9H165
QVMKRIHSLMEKYSE	DDX60	671	Q8IY21
ATIVIAYLMKHTRMT	DUSP10	416	Q9Y6W6
EKASHRMKTPVKYMT	ECPAS	566	Q5VYK3
TIMESPYVMYKKNHE	GRIA4	421	P48058
DTHMKFSLPSSRKEM	PLXNC1	716	O60486
YRSVSEMASHKFKRM	PDE4A	251	P27815
VLPRSMRMHFTYDLK	PIP5K1B	191	O14986
ISMKHPQEMKTYSLS	FOLH1B	306	Q9HBA9
HNILSLPKYSTMERM	HERC6	986	Q8IVU3
VKHAMTMQPYLTTKC	NIPBL	2021	Q6KC79
LSKPQMIMYKTNSSH	PIERCE2	51	H3BRN8
HPMMSKETRQSKLAE	GOLGA6L6	36	A8MZA4
HDKYTLRKSMIPSFM	TUBGCP3	461	Q96CW5
KMVISGMRYHLLSPE	KLHL7	261	Q8IXQ5
MPTKKMYHINETRGL	ANO1	176	Q5XXA6
NKMYLTPSEKHMLLK	CYFIP2	251	Q96F07
KHKYRQTVMFTATMP	DDX23	596	Q9BUQ8
IAKPLHYVTMMRKEV	OR4D6	126	Q8NGJ1
ASLKSNYNLPMHKMI	RPL4	271	P36578
YLTMDSSGPKHLNMK	HSPA9	331	P38646
MYSIPKDKQMLLFTH	HUWE1	246	Q7Z6Z7
MTVKTLHGPAMVKYL	IL17F	1	Q96PD4
PKRAEMKTSMESLIH	NDUFS2	366	O75306
MNNLLPRSVKMHIKY	PIPSL	191	A2A3N6
KSIFKQMKTHPPYTM	FRMD3	91	A2A2Y4
QMKTHPPYTMCFRVK	FRMD3	96	A2A2Y4
IMMKHDFKVTIYLLP	ATR	1516	Q13535
MPFSVYSTLEKHMKK	BCL11B	861	Q9C0K0
FKLLSRAYADVHPMM	CPZ	411	Q66K79
ISKMDPTDAKYHMQR	CDC37	321	Q16543
SLVLTPSHIKAYMLM	CDK7	106	P50613
LRNYKAKMPSHLMLA	C3orf20	311	Q8ND61
HYMKKQPDITEGMRT	CCNA1	231	P78396
SLKKRMEVPDYEMVH	C5orf22	341	Q49AR2
TKSLYRDGMAPMVKS	AGBL4	106	Q5VU57
VMDDTISPYSRMKRH	DEGS1	301	O15121
ISPYSRMKRHQKGEM	DEGS1	306	O15121
VSSLHMMKISYDVVK	COPG2	161	Q9UBF2
LCQKYPRKHSVMMTF	COPG2	386	Q9UBF2
LRVHSYKSMQPEMDR	DRC7	511	Q8IY82
KMEIYRPHKATAEEM	HDAC2	51	Q92769
IMEYKTHTDSIKMPG	EIF4E2	211	O60573
DSSSYLTPMKHMLAA	SLC25A26	81	Q70HW3
RHLTMIKMRPYDANK	S1PR3	136	Q99500
MYIRPSSSHSMDTDK	OR5B17	256	Q8NGF7
LVMYVILRHTKMKTA	OPRL1	71	P41146
SLKAHMKSNPLYTDM	MINAR1	801	Q9UPX6
ETRMYPKLSGLHRSM	NAV1	871	Q8NEY1
HKMTLSPSYRMDDGK	RPUSD4	216	Q96CM3
LPNFYTHTKMTMAKE	RGSL1	191	A5PLK6
SSLEKDMHYAKISSM	RGSL1	306	A5PLK6
KAFVSRYKLMRHMAT	PLAGL1	41	Q9UM63
RYKLMRHMATHSPQK	PLAGL1	46	Q9UM63
TPMLRHLMYKIKSTG	NDUFAF7	41	Q7L592
KAEMLHMYSQKDPLI	SLC38A5	321	Q8WUX1
THDMRKKTFHYMLTI	TAF2	226	Q6P1X5
MKSHESSPKKEVYFM	PIP4K2B	351	P78356
SPMKLFSEYHEKRML	HDHD5	121	Q9BXW7
PKTHEMYLNVMRRFS	PIK3C3	511	Q8NEB9
MKDMSKYKPHILLSQ	SIKE1	61	Q9BRV8
VSTPVLDRYRMSKMH	SHISA6	431	Q6ZSJ9
AMLLYKTMTRPKHFL	NLRP7	806	Q8WX94
MVILTYLDSKLHTPM	OR8K1	51	Q8NGG5
EKFQSKYEPRSHMMD	PDIA4	361	P13667
KHGMDKERYVSLVMP	SRPX	421	P78539
NTMKYMTALHSKPEI	PLK4	541	O00444
MIMDCKYTVPSHVSK	SNRK	226	Q9NRH2
KYHMEMNSKSAPSSR	OSBPL10	171	Q9BXB5
HFTAMPKLLSYRMKK	SNAPC1	136	Q16533
DGSSLPADVHRYMKM	CLPTM1L	186	Q96KA5
KEMHMRSKRIYDNLP	C10orf90	646	Q96M02
KRPSSCTHTMYSIMK	STYK1	346	Q6J9G0
MPSKSLVMEYLAHPS	PTRH2	1	Q9Y3E5
MKRHSMVATPPVTYS	ZNF738	96	Q8NE65
YPSMKKAIAHAMKVA	TTLL8	496	A6PVC2
TEYCPSLSSMQKHMK	ZBTB16	636	Q05516
AEMKTYSHRTMPSAC	SFTPD	21	P35247
MPVIMKNSVYIHKAA	PLEKHD1	416	A6NEE1
LMKEAPTAYSLLIMH	PPAT	176	Q06203
RTHNTLYAPEMLAKM	XPO5	781	Q9HAV4
LMYSRRHSQKKVPMM	TEX13C	476	A0A0J9YWL9
HRMVKVDPETRYMSL	WDR6	851	Q9NNW5
LHPCSKSDPMYSMKR	ZNF770	141	Q6IQ21
KSDPMYSMKRRKNIH	ZNF770	146	Q6IQ21
TMTKATYCKPHMQTK	ZMYM2	856	Q9UBW7
SRKRKSMPTKMPYNH	ZNF366	76	Q8N895
KHTSMYDKVLMLRPE	GTF3C5	141	Q9Y5Q8
LSMTHYMSKKELSRL	TRMT10B	131	Q6PF06
KSHRPIFENSMDKMY	SPATA6	456	Q9NWH7
TSKKMYPHRPVLMVI	SULF2	206	Q8IWU5
MLYKSSDRPAHKVSM	LYPD6B	1	Q8NI32
SKYSMNRHKMTTLTP	NADSYN1	641	Q6IA69