Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDMAP_binding

DIP2C DIP2B

3.40e-055352PF06464
DomainDMAP_binding

DIP2C DIP2B

5.09e-056352SM01137
DomainDMAP1-bd

DIP2C DIP2B

5.09e-056352IPR010506
DomainPWWP

PWWP2A BRPF3

6.35e-0420352SM00293
DomainPWWP

PWWP2A BRPF3

8.42e-0423352PF00855
DomainPWWP_dom

PWWP2A BRPF3

8.42e-0423352IPR000313
DomainPWWP

PWWP2A BRPF3

9.18e-0424352PS50812
DomainAMP-binding

DIP2C DIP2B

1.44e-0330352PF00501
DomainAMP-dep_Synth/Lig

DIP2C DIP2B

1.44e-0330352IPR000873
DomainZinc_finger_PHD-type_CS

BRPF3 KDM5C

6.59e-0365352IPR019786
DomainPHD

BRPF3 KDM5C

8.69e-0375352PF00628
DomainZnf_PHD-finger

BRPF3 KDM5C

9.60e-0379352IPR019787
Pubmed

CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.

DIP2C DIP2B

3.30e-06337217236128
Pubmed

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

FAT4 ANK3

6.02e-051137220351715
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

CCDC15 ANLN AHNAK2

2.72e-0411837330979931
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

DIP2C DIP2B

4.09e-042837231600191
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

DIP2B ANLN KDM5C AHNAK2

4.20e-0433237432786267
Pubmed

HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.

INCENP ANLN

5.35e-043237227114546
Pubmed

α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration.

AFDN ANK3

6.41e-043537237381005
Pubmed

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.

DEPDC5 ANK3

7.96e-043937222802532
Pubmed

The DNA sequence of the human X chromosome.

STARD8 KDM5C FRMD7 KLHL4

8.99e-0440737415772651
GeneFamilyPWWP domain containing

PWWP2A BRPF3

4.17e-04222521147
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

RYBP DIP2B ANK3 ANLN KLHL4

6.41e-072003754dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

RYBP DIP2B ANK3 ANLN KLHL4

6.41e-072003751314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

RYBP DIP2B ANK3 ANLN KLHL4

6.41e-072003758b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

RYBP DIP2B ANK3 ANLN KLHL4

6.41e-07200375272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

RYBP DIP2B ANK3 ANLN KLHL4

6.41e-0720037526b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

RYBP DIP2B ANK3 ANLN KLHL4

6.41e-072003755f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

STK4 AFDN ANK3 KLHL4

1.21e-0517137461318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell368C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DIP2C SLC24A3 MRO AHNAK2

1.26e-051733748cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell368C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DIP2C SLC24A3 MRO AHNAK2

1.26e-05173374fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCellClub-club-15|World / Class top

RYBP INCENP ANLN KDM5C

1.32e-05175374ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 INCENP ANLN AHNAK2

1.41e-05178374c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DIP2C AGBL4 DIP2B ANK3

1.90e-05192374e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DIP2C AGBL4 AFDN ANK3

1.94e-051933743866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DIP2C AGBL4 AFDN ANK3

1.98e-051943747002937e8903e037332a215d00fbc7c7843b33f2
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 AFDN ANK3 AHNAK2

2.23e-05200374ecbe89ff95d046155b984c8c150e0b9e7278f839
Diseaseunipolar depression, bipolar disorder

STK4 FAT4 ANK3 LINC00336

3.46e-05156354EFO_0003761, MONDO_0004985
Diseasecarcinoma (implicated_via_orthology)

STK4 FAT4

2.63e-0364352DOID:305 (implicated_via_orthology)
DiseaseLiver carcinoma

DEPDC5 MRO ANLN PPP1R1A

2.96e-03507354C2239176
DiseaseManic Disorder

STK4 ANK3

3.23e-0371352C0024713
Diseasepsychotic symptoms

DIP2C ANK3

3.50e-0374352EFO_0005940
DiseaseManic

STK4 ANK3

3.88e-0378352C0338831
DiseaseDepression, Bipolar

STK4 ANK3

3.98e-0379352C0005587
DiseaseNonsyndromic Deafness

BDP1 CCDC50

4.18e-0381352C3711374
Diseasesensory perception of sweet taste

DIP2C SIRT5

4.28e-0382352GO_0050916

Protein segments in the cluster

PeptideGeneStartEntry
AEKFRPDMRMLSSPK

AFDN

76

P55196
QRPPDRSKMTMRDFI

BDP1

176

A6H8Y1
MKPRVMKEAVSTPSR

CCDC50

151

Q8IVM0
DREKPMVYTSRMPKL

FAT4

4856

Q6V0I7
SKPMDFSTMRRKLES

BRPF3

631

Q9ULD4
LKRRPSARGSRPMSM

GIT2

501

Q14161
MSNPRKRSIPMRDSN

PGBD4

1

Q96DM1
PNIMFFSTMKRPSRE

CHRNA1

341

P02708
FAPSRMPMKLTSNRR

DEPDC5

601

O75140
KSPEKNPRARMMTST

MUC16

2931

Q8WXI7
MRKRKHMDEPSSPSR

MAJIN

61

Q3KP22
MKSFIKRNTPLRMDP

INCENP

516

Q9NQS7
RKMAERPTAAPRSMT

ANLN

21

Q9NQW6
TAMKPAERSPRNIRM

FRMD7

526

Q6ZUT3
EQKMALPMPTKRRST

DIP2B

116

Q9P265
RARDPSAKKRHMAMR

MRO

56

Q9BYG7
PRPPRSTLRMMETKS

LINC00336

66

Q6ZUF6
ERRSMMQSPRTKPRK

KLHL4

411

Q9C0H6
SHFPPKTRLSMASRM

SLC24A3

336

Q9HC58
RSRSPPTSELMMKFF

CENPJ

856

Q9HC77
PKRSVSLSMRKSGAM

BNIP3L

161

O60238
RDGMAPMVKSTSRPK

AGBL4

111

Q5VU57
RKMAVPMPSKRRSLV

DIP2C

106

Q9Y2E4
MKKMSRTSPADGKPR

ANK3

4326

Q12955
RKAQSMMSRRNPFPL

FBXO16

276

Q8IX29
TADMPKSPFKRRRSM

RSBN1

541

Q5VWQ0
RPKRKMYREEPTSIM

PWWP2A

296

Q96N64
MMRRSPSGLKSPRVS

PRORY

1

Q9H606
MTMGDKKSPTRPKRQ

RYBP

1

Q8N488
SMPKFMRRNKTPDYR

STARD8

551

Q92502
KMPKFRMPSLRRSFR

AHNAK2

5191

Q8IVF2
MLGSMARKKPRNTSR

CCDC15

1

Q0P6D6
LMRKASPMSYFRKLP

TIGD1

541

Q96MW7
MPSRASLKMTPFRAS

nan

21

Q9UF83
MKRRDETMQPAKPSF

STK4

381

Q13043
LKMARPSSSMADFRK

SIRT5

31

Q9NXA8
MSPRQRKKMTRITPT

PPP1R1A

66

Q13522
NKMMRLDSSPVSSPR

ZFC3H1

941

O60293
SPEPCTKMTMRLRRN

KDM5C

301

P41229