Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF5A KIF5C

4.48e-0517122GO:0008574
GeneOntologyMolecularFunctiontubulin binding

KIF5A KIF5C INO80 MAP9

8.99e-05428124GO:0015631
GeneOntologyMolecularFunctionATP hydrolysis activity

NAV1 KIF5A KIF5C INO80

1.01e-04441124GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

NAV1 KIF5A KIF5C INO80

3.60e-04614124GO:0140657
GeneOntologyMolecularFunctionmicrotubule binding

KIF5A KIF5C MAP9

7.21e-04308123GO:0008017
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF5A KIF5C

7.82e-0470122GO:0003777
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

NAV1 KIF5A KIF5C INO80

8.68e-04775124GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

NAV1 KIF5A KIF5C INO80

1.17e-03839124GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

NAV1 KIF5A KIF5C INO80

1.17e-03840124GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

NAV1 KIF5A KIF5C INO80

1.17e-03840124GO:0016818
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF5A KIF5C

2.20e-03118122GO:0003774
GeneOntologyMolecularFunctioncalcium channel activity

TMC1 PKD2L2

2.62e-03129122GO:0005262
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF5A KIF5C INO80 MAP9

3.16e-031099124GO:0008092
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TMC1 PKD2L2

3.57e-03151122GO:0015085
GeneOntologyBiologicalProcessanterograde dendritic transport of neurotransmitter receptor complex

KIF5A KIF5C

6.51e-067122GO:0098971
GeneOntologyBiologicalProcessanterograde axonal protein transport

KIF5A KIF5C

1.11e-059122GO:0099641
GeneOntologyBiologicalProcessaxo-dendritic protein transport

KIF5A KIF5C

1.70e-0511122GO:0099640
GeneOntologyBiologicalProcessprotein localization to presynapse

KIF5A KIF5C

1.70e-0511122GO:1905383
GeneOntologyBiologicalProcessanterograde dendritic transport

KIF5A KIF5C

2.04e-0512122GO:0098937
GeneOntologyBiologicalProcessprotein transport along microtubule

KIF5A KIF5C

4.20e-0517122GO:0098840
GeneOntologyBiologicalProcessmicrotubule-based protein transport

KIF5A KIF5C

4.20e-0517122GO:0099118
GeneOntologyBiologicalProcessdendritic transport

KIF5A KIF5C

5.28e-0519122GO:0098935
GeneOntologyBiologicalProcessmicrotubule-based process

NAV1 KIF5A KIF5C INO80 MAP9

2.06e-041058125GO:0007017
GeneOntologyBiologicalProcesssynaptic vesicle transport

KIF5A KIF5C

4.37e-0454122GO:0048489
GeneOntologyBiologicalProcessanterograde axonal transport

KIF5A KIF5C

4.53e-0455122GO:0008089
GeneOntologyBiologicalProcesssynaptic vesicle localization

KIF5A KIF5C

7.54e-0471122GO:0097479
GeneOntologyBiologicalProcessaxonal transport

KIF5A KIF5C

8.41e-0475122GO:0098930
GeneOntologyBiologicalProcessdetection of mechanical stimulus

TMC1 PKD2L2

8.41e-0475122GO:0050982
GeneOntologyBiologicalProcesscellular response to ionizing radiation

SFRP1 INO80

8.63e-0476122GO:0071479
GeneOntologyBiologicalProcessregulation of bone remodeling

SUCO SFRP1

9.56e-0480122GO:0046850
GeneOntologyCellularComponentmicrotubule

NAV1 KIF5A KIF5C INO80 MAP9

7.22e-06533125GO:0005874
GeneOntologyCellularComponentciliary rootlet

KIF5A KIF5C

3.61e-0516122GO:0035253
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

NAV1 KIF5A KIF5C INO80 MAP9

8.95e-05899125GO:0099513
GeneOntologyCellularComponentdendrite cytoplasm

KIF5A KIF5C

2.21e-0439122GO:0032839
GeneOntologyCellularComponentpostsynaptic cytosol

KIF5A KIF5C

2.95e-0445122GO:0099524
GeneOntologyCellularComponentsupramolecular fiber

NAV1 KIF5A KIF5C INO80 MAP9

3.21e-041179125GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

NAV1 KIF5A KIF5C INO80 MAP9

3.31e-041187125GO:0099081
GeneOntologyCellularComponentkinesin complex

KIF5A KIF5C

3.50e-0449122GO:0005871
GeneOntologyCellularComponentaxon cytoplasm

KIF5A KIF5C

6.74e-0468122GO:1904115
GeneOntologyCellularComponentcytosolic region

KIF5A KIF5C

7.14e-0470122GO:0099522
GeneOntologyCellularComponentaxon

NAV1 KIF5A KIF5C MAP9

1.23e-03891124GO:0030424
GeneOntologyCellularComponentneuron projection cytoplasm

KIF5A KIF5C

1.75e-03110122GO:0120111
GeneOntologyCellularComponentmicrotubule associated complex

KIF5A KIF5C

3.70e-03161122GO:0005875
GeneOntologyCellularComponentgrowth cone

KIF5A KIF5C

8.36e-03245122GO:0030426
GeneOntologyCellularComponentsite of polarized growth

KIF5A KIF5C

8.89e-03253122GO:0030427
GeneOntologyCellularComponentcilium

SSX1 KIF5A KIF5C

1.30e-02898123GO:0005929
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

KIF5A KIF5C

1.37e-02317122GO:0032838
GeneOntologyCellularComponentcytoplasmic region

KIF5A KIF5C

1.74e-02360122GO:0099568
DomainKinesin_motor_CS

KIF5A KIF5C

3.06e-0441122IPR019821
DomainKinesin-like_fam

KIF5A KIF5C

3.37e-0443122IPR027640
Domain-

KIF5A KIF5C

3.53e-04441223.40.850.10
DomainKinesin_motor_dom

KIF5A KIF5C

3.53e-0444122IPR001752
DomainKISc

KIF5A KIF5C

3.53e-0444122SM00129
DomainKINESIN_MOTOR_2

KIF5A KIF5C

3.53e-0444122PS50067
DomainKINESIN_MOTOR_1

KIF5A KIF5C

3.53e-0444122PS00411
DomainKinesin

KIF5A KIF5C

3.53e-0444122PF00225
DomainP-loop_NTPase

NAV1 KIF5A KIF5C INO80

1.56e-03848124IPR027417
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT

KIF5A KIF5C

5.43e-06962M47699
PathwayKEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT

KIF5A KIF5C

1.18e-051362M47763
PathwayKEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT

KIF5A KIF5C

4.15e-052462M47671
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT

KIF5A KIF5C

4.51e-052562M47710
PathwayREACTOME_INSULIN_PROCESSING

KIF5A KIF5C

4.51e-052562M27198
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT

KIF5A KIF5C

4.51e-052562M47775
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT

KIF5A KIF5C

4.88e-052662M47672
PathwayKEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT

KIF5A KIF5C

8.93e-053562M47774
PathwayREACTOME_UCH_PROTEINASES

INO80 ASXL1

5.56e-048762MM15287
PathwayREACTOME_PEPTIDE_HORMONE_METABOLISM

KIF5A KIF5C

5.69e-048862M27211
PathwayREACTOME_UCH_PROTEINASES

INO80 ASXL1

7.63e-0410262M27576
PathwayWP_ALZHEIMERS_DISEASE

KIF5A KIF5C

4.88e-0326162M42565
PathwayREACTOME_DEUBIQUITINATION

INO80 ASXL1

4.91e-0326262MM15286
PathwayREACTOME_DEUBIQUITINATION

INO80 ASXL1

6.36e-0329962M27574
PathwayWP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS

KIF5A KIF5C

7.52e-0332662M39379
PathwayWP_PLEURAL_MESOTHELIOMA

SFRP1 ASXL1

1.34e-0243962M42563
Pubmed

New approach to capture and characterize synaptic proteome.

KIF5A KIF5C

1.09e-07212225352669
Pubmed

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.

KIF5A KIF5C

3.27e-07312217693257
Pubmed

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.

KIF5A KIF5C

3.27e-07312230068641
Pubmed

Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.

KIF5A KIF5C

3.27e-0731227514426
Pubmed

Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport.

KIF5A KIF5C

3.27e-07312221768290
Pubmed

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites.

KIF5A KIF5C

6.55e-07412211986669
Pubmed

KIF5C, a novel neuronal kinesin enriched in motor neurons.

KIF5A KIF5C

6.55e-07412210964943
Pubmed

KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria.

KIF5A KIF5C

1.09e-0651227528108
Pubmed

Chromosomal localization reveals three kinesin heavy chain genes in mouse.

KIF5A KIF5C

1.64e-0661229782088
Pubmed

mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1.

KIF5A KIF5C

2.29e-06712220019668
Pubmed

Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.

KIF5A KIF5C

2.29e-06712221335237
Pubmed

Analysis of Kif5b expression during mouse kidney development.

KIF5A KIF5C

2.29e-06712225885434
Pubmed

Kinesin transports RNA: isolation and characterization of an RNA-transporting granule.

KIF5A KIF5C

2.29e-06712215312650
Pubmed

Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins.

KIF5A KIF5C

3.92e-0691229624122
Pubmed

Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.

KIF5A KIF5C

4.90e-061012221976701
Pubmed

Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.

KIF5A KIF5C

7.19e-061212216301330
Pubmed

The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.

KIF5A KIF5C

7.19e-061212216018997
Pubmed

The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.

KIF5A KIF5C

7.19e-061212215834408
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF5A KIF5C

3.26e-05251229275178
Pubmed

High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.

NAV1 CPVL

1.32e-045012229560723
Pubmed

Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.

KIF5A KIF5C

2.75e-047212234882091
InteractionELF4 interactions

CPVL INO80 ASXL1

3.84e-05115123int:ELF4
InteractionBRK1 interactions

NAV1 KIF5A KIF5C

4.80e-05124123int:BRK1
InteractionCOG6 interactions

NAV1 KIF5A KIF5C

1.10e-04164123int:COG6
InteractionFHIP1A interactions

KIF5A KIF5C

1.70e-0433122int:FHIP1A
InteractionNUP62CL interactions

NAV1 KIF5A

2.14e-0437122int:NUP62CL
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF5A KIF5C

1.32e-044672622
CoexpressionRORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN

SFRP1 KIF5C

7.22e-0528122M15762
CoexpressionGSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP

SFRP1 CPVL ASXL1

8.62e-05196123M7666
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_UP

NAV1 SFRP1 KIF5C

8.88e-05198123M9924
CoexpressionSCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN

NAV1 SFRP1

1.88e-0445122M1369
CoexpressionSCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN

NAV1 SFRP1

1.88e-0445122MM576
ToppCellCOVID-CD4-CD8_1|COVID / Condition, Cell_class and T cell subcluster

KIF5A KIF5C ASXL1

1.46e-05185123c634bb04a081ae3214b68f6e4a147db5b2b916ed
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

KIF5A KIF5C MAP9

1.69e-051941238aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SFRP1 KIF5A KIF5C

1.79e-0519812352ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SFRP1 KIF5A KIF5C

1.79e-0519812350dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

NAV1 KIF5A KIF5C

1.85e-05200123979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellKidney|World / Skin and Kidney Cells in Lupus Nephritis Patients.

SFRP1 CPVL MAP9

1.85e-052001231f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Ptprz1_(Ptprz1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

1.47e-046812289d337147899a978a7467db24e876a613bdd2288
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Ptprz1_(Ptprz1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

1.47e-04681229ce22a6dea3c17d5352572ea0dabe6c6120b9f82
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

2.58e-04901226adc78899a08d48da8ed4618ecf866c9ed9be059
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

2.58e-0490122a74f8172780adc1410e36e2718412010ee0ebf1f
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

2.58e-0490122909ad62d175b657d8e541b0981ce8fed0ba7ed6c
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P3|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

2.58e-0490122a0baaf2b3cf07d457f0d242fc213689cba6fd449
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

2.58e-0490122ab4b08c6ac8695b38f841c0ecf2bb2c032111d04
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NAV1 TMC1

2.58e-0490122936c5078677ec934f3049d8aa5a14d930aa2e6dc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Intermediate|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SFRP1 PKD2L2

3.78e-0410912248f675d36fece070410eb9cfe64805f4629e290f
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC1 PKD2L2

5.04e-0412612254247ce9ee0a4f123f1fb225600a4ec698510a86
ToppCell3'_v3-Lung-Lymphocytic_T_CD8-Trm_gut_CD8|Lung / Manually curated celltypes from each tissue

KIF5A TMC1

6.31e-041411227cbe8abdd004430d58ce31e0b613894a4cf6726e
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma|TCGA-Uterus / Sample_Type by Project: Shred V9

SUCO PKD2L2

7.22e-041511222810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV1 CPVL

7.32e-041521220769857f25da2e6169420818e61d65e33b7277b1
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 CPVL

7.51e-041541225967a0a33456d5930fc492a700ebb015ac050abb
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 CPVL

7.61e-04155122fab281db4c275d51240b122be78713c839ba5a95
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAV1 CPVL

7.71e-041561222474402f563e9e9f37351cfabc8c012e42a1d8c5
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP1 KIF5A

7.80e-04157122370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 CPVL

7.80e-04157122e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 CPVL

7.90e-04158122e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIF5C MAP9

8.00e-041591222233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCellCOVID-19_Moderate-MAIT|World / disease group, cell group and cell class

SFRP1 KIF5C

8.10e-04160122bf73c5fe87c1f243edec17d7a2c30fae5e2cfd6b
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

NAV1 CPVL

8.20e-041611222f068ee643de2f647c289779a6624265ab9a749b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF5A KIF5C

8.20e-0416112269f5e759c0925daa37e0177a9cc3154842906bf6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIF5C MAP9

8.31e-0416212280317c4253bf8e897782e562f29835f181c65b98
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 CPVL

8.41e-04163122a09449a502627aa369db600dba5bda93de7ce5c0
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF5A KIF5C

8.51e-0416412257301178e420983c0cb72178e288a3a0449fdda3
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 CPVL

8.51e-04164122ed888b55d9c685096fd785878fcb264f4fee88d6
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAV1 CPVL

8.51e-04164122283f14d56bdd67f05444c792e53b8f2bfe508107
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic-dendritic_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAV1 CPVL

8.51e-041641223088d5fa240d2f4a6e21281f7ac932aea2f9af49
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP1 PKD2L2

8.61e-04165122cca3ba9d7d30404e3e683b8cfd500c348a4974b9
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF5A KIF5C

8.61e-0416512202cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF5A KIF5C

8.61e-041651226d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

NAV1 CPVL

8.72e-041661229f14e3ef19d5903278c040be1c477501237173fa
ToppCelldroplet-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 KIF5A

8.72e-04166122c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF5A KIF5C

8.72e-04166122f0912ce0df5ede3bc5e7c99ccfe4decc16c6064e
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 CPVL

8.72e-04166122b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

NAV1 CPVL

8.72e-041661220590e404f45afce90e20f93f90a3def83949c66b
ToppCelldroplet-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 KIF5A

8.72e-0416612294c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCellICU-NoSEP-Myeloid-cDC2|ICU-NoSEP / Disease, Lineage and Cell Type

NAV1 CPVL

8.82e-041671225b7b731944d888591279ef6167b3ae8cab3f6886
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 CPVL

8.82e-04167122e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAV1 TMC1

8.82e-041671228b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 CPVL

8.93e-04168122d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCellControl-Epithelial_airway-Club_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF5C TMC1

8.93e-04168122e85bc5398eb36b2b0773a8a7082e3ba740452165
ToppCellControl-Epithelial_airway-Club_cells-Airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF5C TMC1

8.93e-04168122ce87981f4da2779de952c2e5d2bbcdabb265e705
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 KIF5A

9.03e-041691223f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 KIF5A

9.03e-0416912226de495c7562e0740689d0f78e803698e3e793db
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF5A KIF5C

9.03e-04169122b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 CPVL

9.03e-04169122ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 CPVL

9.14e-041701227bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUCO CPVL

9.14e-04170122c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 KIF5A

9.14e-04170122670027daec5a10dfa12246f1497b58db21d32a22
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 CPVL

9.14e-04170122a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NAV1 CPVL

9.24e-0417112204346d4eb726875e3537e215ea081a0318ca4ddd
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAV1 CPVL

9.24e-04171122c2b7bbabc8f9afa8a1157b567d5f962d4b242919
ToppCellChildren_(3_yrs)-Immune-dendritic_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV1 CPVL

9.24e-041711226a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CPVL KIF5C

9.24e-041711223d26ef58fe5231373d7df9ac79d225546918cf82
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPVL KIF5C

9.35e-041721223acf35b774ebc0f9e96299d0bd3e9d03bbf6b90c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPVL KIF5C

9.35e-041721224d04df9776394ea156ed5822f92ae74fdefbaa3d
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP1 KIF5A

9.35e-04172122ba70b6110b70afb1870e8dcaf58c507b8c7d918e
ToppCellE15.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF5A KIF5C

9.35e-04172122a8b33d8ebc56e442a2ad6ac7dafd0c887571bd95
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP1 KIF5A

9.35e-04172122bc1b889ac5e07b8324ae5837eca911f9c865e959
ToppCellLeuk-UTI-Myeloid-cDC1|Leuk-UTI / Disease, Lineage and Cell Type

NAV1 CPVL

9.46e-04173122226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCellBac-SEP-Myeloid-cDC1|Bac-SEP / Disease, Lineage and Cell Type

NAV1 CPVL

9.46e-04173122f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCellURO-Myeloid-cDC1|URO / Disease, Lineage and Cell Type

NAV1 CPVL

9.46e-0417312257f4e9f39ef6e02dca76f3dd0b39a0871917ed5a
ToppCelldroplet-Marrow-nan-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 SFRP1

9.46e-041731226d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCellwk_20-22-Epithelial-PNS|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SFRP1 KIF5C

9.46e-0417312217b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF5A KIF5C

9.57e-04174122742c73c9e090848b464323cb17579b86658c6792
ToppCellTuft-tuft-4|World / Class top

CPVL PKD2L2

9.57e-04174122d6f306ebf66061bf9e9742000bfedce12d277452
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF5A KIF5C

9.57e-041741227fed9722e64c60843092f2ba71256e3043011ef6
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

CPVL PKD2L2

9.57e-041741225ec8a48a390379d6c422120dce46437a77da67cc
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPVL KIF5C

9.68e-041751223bdccb4037053795d62ab5b6fcc09cdd406f9b50
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPVL KIF5C

9.68e-04175122770546ddaa49ee482c4c7577ab76efbc6c304a29
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF5A KIF5C

9.68e-0417512265571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFRP1 PKD2L2

9.68e-04175122a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCellwk_20-22-Epithelial-PNS-Late_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SFRP1 KIF5C

9.79e-0417612281924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

NAV1 CPVL

9.79e-04176122195393b38f1335f2cb96125616d75c164a6026c2
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF5A KIF5C

9.79e-0417612204dad262929581872e5bbc66cd8182c963e7e52f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAV1 CPVL

9.79e-04176122269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCellIIH-mDC1-|IIH / Condition, Cell_class and T cell subcluster

NAV1 CPVL

9.79e-04176122bb80a3e595d071f6cc8b042984b8d9490e377eef
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|metastatic_Brain / Location, Cell class and cell subclass

NAV1 CPVL

9.79e-04176122b9ba7026dee2272c0b483dc0cfa39f74b75f1634
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC2|lymph-node_spleen / Manually curated celltypes from each tissue

NAV1 CPVL

9.79e-0417612272a3bbab0540ae3e3c94b9573cdb9298a024dbc4
ToppCellIIH-mDC1|IIH / Condition, Cell_class and T cell subcluster

NAV1 CPVL

9.79e-04176122a75dc132a1061006fd1cb305bd314784fca07ea6
ToppCellDendritic_Cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

NAV1 CPVL

9.90e-04177122d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP9 PKD2L2

9.90e-04177122ff97398d2adb83063b7c53a264bfae86ea7ea304
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

NAV1 CPVL

9.90e-0417712233cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP9 PKD2L2

9.90e-04177122c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCellfacs-Marrow-KLS-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 KIF5A

1.00e-031781226bad4439a1692332f70135ff446a1048fa4c399d
ToppCellfacs-Marrow-KLS-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 KIF5A

1.00e-031781223f6feb4ed7779cf5684f52939350b41d7718c3c6
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

NAV1 CPVL

1.01e-03179122ec995ccd6e1dbd06287ad836c232d9aed1cf94a8
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF5A KIF5C

1.01e-03179122d96741c5c551e36421b2ad938072ab7d506c3835
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF5A KIF5C

1.01e-03179122228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SUCO TMC1

1.01e-03179122362c003503190dc272fa89185a83a65e063d7a67
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SUCO TMC1

1.01e-03179122e0eec8d48868c76c3e879f219357c62ceff1bc76
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SUCO TMC1

1.01e-031791227d2e6bde00a9ab4cb21bd48b140ce205e36f9d77
ComputationalIntracellular transport (MT cytoskeleton and motors).

KIF5A KIF5C

1.01e-042182MODULE_253
ComputationalGenes in the cancer module 196.

KIF5A KIF5C

1.22e-042382MODULE_196
ComputationalGenes in the cancer module 533.

KIF5A KIF5C

4.72e-044582MODULE_533
ComputationalIntermediate filaments and MT.

KIF5A KIF5C

1.08e-036882MODULE_438
ComputationalGenes in the cancer module 99.

SSX1 SFRP1 KIF5A

1.80e-0335783MODULE_99
Diseasespinal muscular atrophy (implicated_via_orthology)

KIF5A KIF5C

5.45e-069122DOID:12377 (implicated_via_orthology)
Diseasemotor neuron disease (implicated_via_orthology)

KIF5A KIF5C

9.98e-0612122DOID:231 (implicated_via_orthology)
Diseaseleiomyoma (is_marker_for)

SFRP1 KIF5C

5.70e-0528122DOID:127 (is_marker_for)
DiseaseFEV/FEC ratio

NAV1 SFRP1 CPVL TMC1 ASXL1

7.68e-051228125EFO_0004713
Diseasehereditary spastic paraplegia (implicated_via_orthology)

KIF5A KIF5C

1.36e-0443122DOID:2476 (implicated_via_orthology)
Diseaseneurodegenerative disease (implicated_via_orthology)

KIF5A KIF5C

1.53e-03145122DOID:1289 (implicated_via_orthology)
Diseasephosphatidylethanolamine measurement

NAV1 SFRP1

2.17e-03173122EFO_0010228
Diseasecortical thickness

NAV1 SFRP1 CPVL

9.12e-031113123EFO_0004840
Diseasecortical surface area measurement

NAV1 SFRP1 CPVL

1.53e-021345123EFO_0010736
DiseaseLiver carcinoma

SSX1 SFRP1

1.74e-02507122C2239176

Protein segments in the cluster

PeptideGeneStartEntry
MEKEKKVEQWKEKFF

ASXL1

341

Q8IXJ9
KEMLLYWKKYEKVEK

INO80

341

Q9ULG1
FEKWKEKKMEYLKEK

MAP9

516

Q49MG5
YKKAEKKVWKIFKSD

CPVL

411

Q9H3G5
QWKKKYEKEKEKTKA

KIF5A

341

Q12840
KDADAKKKKKKSWVY

NAV1

1201

Q8NEY1
EWKKKYEKEKEKNKT

KIF5C

341

O60282
KWDKKNKEFKNFMKK

SFRP1

286

Q8N474
YFSKKEWKKMKYSEK

SSX1

31

Q16384
WKMEKKIEVLKEAKK

TMC1

111

Q8TDI8
KKWKERLEKKYYSME

PKD2L2

566

Q9NZM6
FDEWKKKVMEVEKEK

SUCO

271

Q9UBS9