Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycosaminoglycan binding	CHRD LAMC2 FBN1 ADAMTS5 COL25A1 SLIT1 STAB1	2.88e-06	268	47	7	GO:0005539
GeneOntologyMolecularFunction	heparin binding	CHRD LAMC2 FBN1 ADAMTS5 COL25A1 SLIT1	5.65e-06	192	47	6	GO:0008201
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMC2 FRAS1 FBN1 COL25A1 MUC5AC	7.81e-05	188	47	5	GO:0005201
GeneOntologyMolecularFunction	sulfur compound binding	CHRD LAMC2 FBN1 ADAMTS5 COL25A1 SLIT1	1.05e-04	323	47	6	GO:1901681
GeneOntologyMolecularFunction	acetylcholine binding	CHRFAM7A CHRNA7	4.16e-04	13	47	2	GO:0042166
GeneOntologyMolecularFunction	chloride channel regulator activity	CHRFAM7A CHRNA7	5.58e-04	15	47	2	GO:0017081
GeneOntologyMolecularFunction	adenylate cyclase binding	CHRFAM7A CHRNA7	6.37e-04	16	47	2	GO:0008179
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP2 STAB1	6.37e-04	16	47	2	GO:0005041
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRFAM7A CHRNA7	7.21e-04	17	47	2	GO:0022848
GeneOntologyMolecularFunction	toxic substance binding	CHRFAM7A CHRNA7	8.10e-04	18	47	2	GO:0015643
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP2 STAB1	1.11e-03	21	47	2	GO:0030228
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRFAM7A CHRNA7	1.33e-03	23	47	2	GO:0015464
GeneOntologyMolecularFunction	amyloid-beta binding	COL25A1 CHRFAM7A CHRNA7	1.78e-03	102	47	3	GO:0001540
GeneOntologyMolecularFunction	heparan sulfate proteoglycan binding	CHRD SLIT1	2.11e-03	29	47	2	GO:0043395
GeneOntologyMolecularFunction	PDZ domain binding	LRP2 FZD8 ADGRB1	3.04e-03	123	47	3	GO:0030165
GeneOntologyBiologicalProcess	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	5.30e-06	2	48	2	GO:0001988
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	LRP2 LAMC2 COL25A1 PTPRD ATG7 CHRFAM7A CHRNA7 PLXNB1 SLIT1 ADGRB1	6.95e-06	748	48	10	GO:0048667
GeneOntologyBiologicalProcess	neuron projection morphogenesis	LRP2 LAMC2 COL25A1 PTPRD ATG7 CHRFAM7A CHRNA7 PLXNB1 SLIT1 ADGRB1	1.28e-05	802	48	10	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	LRP2 LAMC2 COL25A1 PTPRD ATG7 CHRFAM7A CHRNA7 PLXNB1 SLIT1 ADGRB1	1.53e-05	819	48	10	GO:0120039
GeneOntologyBiologicalProcess	baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	1.59e-05	3	48	2	GO:0001982
GeneOntologyBiologicalProcess	cell projection morphogenesis	LRP2 LAMC2 COL25A1 PTPRD ATG7 CHRFAM7A CHRNA7 PLXNB1 SLIT1 ADGRB1	1.65e-05	826	48	10	GO:0048858
GeneOntologyBiologicalProcess	generation of ovulation cycle rhythm	CHRFAM7A CHRNA7	3.17e-05	4	48	2	GO:0060112
GeneOntologyBiologicalProcess	sensory processing	CHRFAM7A CHRNA7	5.28e-05	5	48	2	GO:0050893
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	CHRFAM7A CHRNA7	7.91e-05	6	48	2	GO:0001978
GeneOntologyBiologicalProcess	circulatory system development	LRP2 FZD8 SLC2A10 CHRD FBN1 ADAMTS5 SPINT1 ATG7 CHRNA7 PKD1L1 STAB1 ADGRB1	8.55e-05	1442	48	12	GO:0072359
GeneOntologyBiologicalProcess	neuron projection arborization	LRP2 CHRFAM7A CHRNA7	9.42e-05	38	48	3	GO:0140058
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by baroreceptor feedback	CHRFAM7A CHRNA7	1.47e-04	8	48	2	GO:0003025
GeneOntologyBiologicalProcess	positive regulation of CoA-transferase activity	CHRFAM7A CHRNA7	1.89e-04	9	48	2	GO:1905920
GeneOntologyBiologicalProcess	regulation of CoA-transferase activity	CHRFAM7A CHRNA7	2.88e-04	11	48	2	GO:1905918
GeneOntologyBiologicalProcess	behavioral response to nicotine	CHRFAM7A CHRNA7	2.88e-04	11	48	2	GO:0035095
GeneOntologyBiologicalProcess	axonogenesis	LRP2 LAMC2 COL25A1 ATG7 PLXNB1 SLIT1 ADGRB1	3.13e-04	566	48	7	GO:0007409
GeneOntologyBiologicalProcess	response to food	FBN1 CHRFAM7A CHRNA7	3.34e-04	58	48	3	GO:0032094
GeneOntologyBiologicalProcess	regulation of synapse structural plasticity	CHRFAM7A CHRNA7	3.45e-04	12	48	2	GO:0051823
GeneOntologyBiologicalProcess	cell morphogenesis	LRP2 LAMC2 COL25A1 PTPRD ATG7 CHRFAM7A CHRNA7 PLXNB1 SLIT1 ADGRB1	3.54e-04	1194	48	10	GO:0000902
GeneOntologyBiologicalProcess	regulation of synaptic transmission, dopaminergic	CHRFAM7A CHRNA7	4.07e-04	13	48	2	GO:0032225
GeneOntologyBiologicalProcess	presynaptic modulation of chemical synaptic transmission	CHRD CHRFAM7A CHRNA7	5.10e-04	67	48	3	GO:0099171
GeneOntologyBiologicalProcess	dendrite arborization	CHRFAM7A CHRNA7	5.46e-04	15	48	2	GO:0140059
GeneOntologyBiologicalProcess	endocytosis	LRP2 CLEC10A ATG7 ATG3 CHRFAM7A CHRNA7 STAB1 ADGRB1	5.87e-04	827	48	8	GO:0006897
GeneOntologyBiologicalProcess	protein import	LRP2 CHRD	6.23e-04	16	48	2	GO:0017038
GeneOntologyBiologicalProcess	neuron projection development	LRP2 LAMC2 COL25A1 PTPRD ATG7 CHRFAM7A CHRNA7 PLXNB1 SLIT1 ADGRB1	6.32e-04	1285	48	10	GO:0031175
GeneOntologyBiologicalProcess	axon development	LRP2 LAMC2 COL25A1 ATG7 PLXNB1 SLIT1 ADGRB1	6.65e-04	642	48	7	GO:0061564
GeneOntologyBiologicalProcess	behavioral response to ethanol	CHRFAM7A CHRNA7	7.05e-04	17	48	2	GO:0048149
GeneOntologyBiologicalProcess	import into cell	LRP2 SLC2A10 CLEC10A ATG7 ATG3 CHRFAM7A CHRNA7 STAB1 ADGRB1	7.27e-04	1074	48	9	GO:0098657
GeneOntologyBiologicalProcess	negative regulation of BMP signaling pathway	LRP2 CHRD FBN1	8.57e-04	80	48	3	GO:0030514
GeneOntologyBiologicalProcess	regulation of amyloid fibril formation	CHRFAM7A CHRNA7	8.84e-04	19	48	2	GO:1905906
GeneOntologyBiologicalProcess	synapse organization	CHRD PTPRD CHRFAM7A CHRNA7 PLXNB1 SLIT1 ADGRB1	9.73e-04	685	48	7	GO:0050808
GeneOntologyBiologicalProcess	regulation of response to drug	CHRFAM7A CHRNA7	1.08e-03	21	48	2	GO:2001023
GeneOntologyCellularComponent	spine apparatus membrane	CHRFAM7A CHRNA7	1.55e-05	3	48	2	GO:0098897
GeneOntologyCellularComponent	basement membrane	LAMB4 LAMC2 FRAS1 FBN1	1.76e-04	122	48	4	GO:0005604
GeneOntologyCellularComponent	spine apparatus	CHRFAM7A CHRNA7	1.84e-04	9	48	2	GO:0097444
GeneOntologyCellularComponent	extracellular matrix	LAMB4 LAMC2 FRAS1 FBN1 ADAMTS5 COL25A1 MUC5AC	6.98e-04	656	48	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	LAMB4 LAMC2 FRAS1 FBN1 ADAMTS5 COL25A1 MUC5AC	7.11e-04	658	48	7	GO:0030312
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRFAM7A CHRNA7	7.72e-04	18	48	2	GO:0005892
GeneOntologyCellularComponent	glycinergic synapse	CHRFAM7A CHRNA7	9.55e-04	20	48	2	GO:0098690
GeneOntologyCellularComponent	axolemma	CHRFAM7A CHRNA7	1.05e-03	21	48	2	GO:0030673
GeneOntologyCellularComponent	cholinergic synapse	CHRFAM7A CHRNA7	1.16e-03	22	48	2	GO:0098981
GeneOntologyCellularComponent	collagen-containing extracellular matrix	LAMB4 LAMC2 FRAS1 FBN1 ADAMTS5 COL25A1	1.28e-03	530	48	6	GO:0062023
GeneOntologyCellularComponent	phagophore assembly site	ATG7 ATG3	3.62e-03	39	48	2	GO:0000407
MousePheno	aortic elastic tissue lesions	SLC2A10 FBN1	8.39e-06	2	41	2	MP:0002964
MousePheno	airway basal cell hyperplasia	CHRFAM7A CHRNA7	8.39e-06	2	41	2	MP:0011115
MousePheno	abnormal airway basal cell differentiation	CHRFAM7A CHRNA7	8.39e-06	2	41	2	MP:0011114
MousePheno	abnormal airway basal cell morphology	CHRFAM7A CHRNA7	8.39e-06	2	41	2	MP:0011113
MousePheno	abnormal nicotine-mediated receptor currents	CHRFAM7A CHRNA7	5.02e-05	4	41	2	MP:0009475
MousePheno	failure of neuromuscular synapse presynaptic differentiation	CHRFAM7A CHRNA7	1.25e-04	6	41	2	MP:0001054
MousePheno	lethality during fetal growth through weaning, complete penetrance	LRP2 CHRD LAMC2 FRAS1 FBN1 COL25A1 ATG7 ATG3 CHRFAM7A DISP1 CHRNA7 PKD1L1	1.95e-04	1269	41	12	MP:0011111
MousePheno	abnormal basement membrane morphology	LAMC2 FRAS1 SPINT1	2.15e-04	40	41	3	MP:0004272
MousePheno	abnormal GABAergic neuron physiology	CHRFAM7A CHRNA7	2.32e-04	8	41	2	MP:0011987
MousePheno	heart right ventricle hypertrophy	LRP2 CHRD FBN1	2.48e-04	42	41	3	MP:0000276
Domain	VWC	CHRD FRAS1 MUC5AC PXDNL	6.89e-07	28	47	4	PF00093
Domain	VWFC_1	CHRD FRAS1 MUC5AC PXDNL	1.95e-06	36	47	4	PS01208
Domain	VWC	CHRD FRAS1 MUC5AC PXDNL	2.44e-06	38	47	4	SM00214
Domain	VWFC_2	CHRD FRAS1 MUC5AC PXDNL	2.44e-06	38	47	4	PS50184
Domain	Growth_fac_rcpt_	LRP2 LAMC2 FRAS1 FBN1 SLIT1 STAB1	2.50e-06	156	47	6	IPR009030
Domain	VWF_dom	CHRD FRAS1 MUC5AC PXDNL	3.67e-06	42	47	4	IPR001007
Domain	EGF	LRP2 LAMC2 FRAS1 FBN1 SLIT1 STAB1	2.60e-05	235	47	6	SM00181
Domain	EGF-like_dom	LRP2 LAMC2 FRAS1 FBN1 SLIT1 STAB1	3.59e-05	249	47	6	IPR000742
Domain	EGF_1	LRP2 LAMB4 LAMC2 FBN1 SLIT1 STAB1	4.10e-05	255	47	6	PS00022
Domain	EGF-like_CS	LRP2 LAMB4 LAMC2 FBN1 SLIT1 STAB1	4.67e-05	261	47	6	IPR013032
Domain	EGF_2	LRP2 LAMB4 LAMC2 FBN1 SLIT1 STAB1	5.08e-05	265	47	6	PS01186
Domain	EGF_LAM_2	LAMB4 LAMC2 STAB1	5.78e-05	30	47	3	PS50027
Domain	EGF_LAM_1	LAMB4 LAMC2 STAB1	5.78e-05	30	47	3	PS01248
Domain	Laminin_EGF	LAMB4 LAMC2 STAB1	9.24e-05	35	47	3	PF00053
Domain	EGF_Lam	LAMB4 LAMC2 STAB1	9.24e-05	35	47	3	SM00180
Domain	Laminin_EGF	LAMB4 LAMC2 STAB1	1.18e-04	38	47	3	IPR002049
Domain	Ptc/Disp	DISP3 DISP1	2.21e-04	9	47	2	IPR003392
Domain	Patched	DISP3 DISP1	2.21e-04	9	47	2	PF02460
Domain	EGF_CA	LRP2 FBN1 SLIT1 STAB1	2.49e-04	122	47	4	SM00179
Domain	EGF-like_Ca-bd_dom	LRP2 FBN1 SLIT1 STAB1	2.65e-04	124	47	4	IPR001881
Domain	SSD	DISP3 DISP1	4.75e-04	13	47	2	IPR000731
Domain	SSD	DISP3 DISP1	4.75e-04	13	47	2	PS50156
Domain	TIL_dom	LRP2 MUC5AC	5.53e-04	14	47	2	IPR002919
Domain	CTCK_1	MUC5AC SLIT1	9.24e-04	18	47	2	PS01185
Domain	VWC_out	FRAS1 MUC5AC	1.03e-03	19	47	2	SM00215
Domain	CT	MUC5AC SLIT1	1.39e-03	22	47	2	SM00041
Domain	-	CHRFAM7A CHRNA7	1.52e-03	23	47	2	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRFAM7A CHRNA7	1.52e-03	23	47	2	IPR027361
Domain	Cys_knot_C	MUC5AC SLIT1	1.79e-03	25	47	2	IPR006207
Domain	CTCK_2	MUC5AC SLIT1	1.79e-03	25	47	2	PS01225
Domain	EGF_Ca-bd_CS	LRP2 FBN1 SLIT1	1.87e-03	97	47	3	IPR018097
Domain	cEGF	LRP2 FBN1	1.94e-03	26	47	2	IPR026823
Domain	cEGF	LRP2 FBN1	1.94e-03	26	47	2	PF12662
Domain	EGF_CA	LRP2 FBN1 SLIT1	1.98e-03	99	47	3	PS01187
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP2 FBN1 SLIT1	2.40e-03	106	47	3	IPR000152
Domain	EGF_3	LRP2 FBN1 SLIT1 STAB1	2.85e-03	235	47	4	PS50026
Domain	GPS	PKD1L1 ADGRB1	3.70e-03	36	47	2	PS50221
Domain	GPS	PKD1L1 ADGRB1	3.90e-03	37	47	2	IPR000203
Domain	EGF	LRP2 SLIT1 STAB1	3.92e-03	126	47	3	PF00008
Domain	LDLR_class-A_CS	LRP2 SPINT1	4.55e-03	40	47	2	IPR023415
Pubmed	Congenital Diaphragmatic Hernia Overview	LRP2 SLC2A10 FRAS1 FBN1	4.99e-07	46	48	4	20301533
Pubmed	Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	38070724
Pubmed	Inflammatory cytokines decrease the expression of nicotinic acetylcholine receptor during the cell maturation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	19626424
Pubmed	Episodic memory performance predicted by the 2bp deletion in exon 6 of the "alpha 7-like" nicotinic receptor subunit gene.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	17012698
Pubmed	Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	26451017
Pubmed	Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	34453977
Pubmed	Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	24757672
Pubmed	Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	26999808
Pubmed	Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	27129924
Pubmed	Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	17291692
Pubmed	Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23521765
Pubmed	Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	28258105
Pubmed	The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	19344760
Pubmed	Loss of α7nAChR enhances endothelial-to-mesenchymal transition after myocardial infarction via NF-κB activation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	35926661
Pubmed	The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	17640819
Pubmed	Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23431157
Pubmed	Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	29114104
Pubmed	Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	33995108
Pubmed	E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	32552811
Pubmed	Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	24836856
Pubmed	Modulation of the MAPKs pathways affects Aβ-induced cognitive deficits in Alzheimer's disease via activation of α7nAChR.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	31904546
Pubmed	Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	15948184
Pubmed	Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	35678315
Pubmed	Age-Associated Tooth Loss and Oral Microbial Dysbiosis in a Mouse Genetic Model of Chronic Nicotine Exposure.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	33117372
Pubmed	Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	12628457
Pubmed	Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	25157794
Pubmed	Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	19615981
Pubmed	Splenic nerve denervation attenuates depression-like behaviors in Chrna7 knock-out mice via the spleen-gut-brain axis.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	38944290
Pubmed	Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	28243714
Pubmed	Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	31202708
Pubmed	Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	22246862
Pubmed	Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	24298024
Pubmed	Lung eosinophilia induced by house dust mites or ovalbumin is modulated by nicotinic receptor α7 and inhibited by cigarette smoke.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	29975102
Pubmed	α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	29580318
Pubmed	Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	35479080
Pubmed	[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].	CHRFAM7A CHRNA7	1.87e-06	2	48	2	38597441
Pubmed	Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	27471776
Pubmed	Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	22688057
Pubmed	α7 Nicotinic acetylcholine receptor agonist attenuates neuropathological changes associated with intracerebral hemorrhage in mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	22820264
Pubmed	Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	33953172
Pubmed	Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	32028688
Pubmed	Genetic variation in CHRNA7 and CHRFAM7A is associated with nicotine dependence and response to varenicline treatment.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	30089821
Pubmed	Nicotinic acetylcholine receptor activation reduces skeletal muscle inflammation of mdx mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	20615555
Pubmed	Nicotine physical dependence in the mouse: involvement of the alpha7 nicotinic receptor subtype.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	15896732
Pubmed	Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	30429582
Pubmed	A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	21501254
Pubmed	α7-cholinergic receptor mediates vagal induction of splenic norepinephrine.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	21339364
Pubmed	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	21368056
Pubmed	Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	24289814
Pubmed	Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	19949071
Pubmed	Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	1400473
Pubmed	Reversible inhibition of GABAA receptors by alpha7-containing nicotinic receptors on the vertebrate postsynaptic neurons.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	17204496
Pubmed	Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	26937017
Pubmed	α7 nicotinic receptors play a role in regulation of cardiac hemodynamics.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	37017608
Pubmed	Impaired hippocampal theta oscillations in the mice null alpha7 nicotinic acetylcholine receptors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23795917
Pubmed	Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	36603528
Pubmed	Endogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	20592195
Pubmed	Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	26650489
Pubmed	Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	11854451
Pubmed	Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	22848433
Pubmed	Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23842742
Pubmed	Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	17292512
Pubmed	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	16650968
Pubmed	Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	35413868
Pubmed	Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23637989
Pubmed	Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7).	CHRFAM7A CHRNA7	1.87e-06	2	48	2	9782083
Pubmed	Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	24462939
Pubmed	Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	29261717
Pubmed	Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	18199426
Pubmed	Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	22490926
Pubmed	Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	36997969
Pubmed	A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	15364017
Pubmed	Choline, an alpha7 nicotinic acetylcholine receptor agonist, alleviates hyperalgesia in a rat osteoarthritis model.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23769729
Pubmed	Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	15944242
Pubmed	Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23270857
Pubmed	Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	18077004
Pubmed	Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	19462340
Pubmed	Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	16923147
Pubmed	NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	11790782
Pubmed	A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	33422641
Pubmed	Nicotinic ACh receptor α7 inhibits PDGF-induced migration of vascular smooth muscle cells by activating mitochondrial deacetylase sirtuin 3.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	30270436
Pubmed	Activation of α-7 Nicotinic Acetylcholine Receptor Attenuates Cardiac Inflammation Through NLRP3/Caspase-1/IL-18 Pathway.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	34988776
Pubmed	Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	37746145
Pubmed	A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	19631623
Pubmed	Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	15770102
Pubmed	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	24326163
Pubmed	Loss of α7 nicotinic acetylcholine receptors in GABAergic neurons causes sex-dependent decreases in radial glia-like cell quantity and impairments in cognitive and social behavior.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	33398432
Pubmed	Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23811428
Pubmed	beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	20374280
Pubmed	Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	38185761
Pubmed	Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	20720594
Pubmed	α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	22624500
Pubmed	Involvement of acetylcholine-α7nAChR in the protective effects of arterial baroreflex against ischemic stroke.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	23106973
Pubmed	Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	33902624
Pubmed	Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	17019565
Pubmed	Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	19100751
Pubmed	Identification of an alternatively processed nicotinic receptor alpha7 subunit RNA in mouse brain.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	14499477
Pubmed	Multiple calcium channels and kinases mediate alpha7 nicotinic receptor neuroprotection in PC12 cells.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	15969741
Pubmed	Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	35883638
Pubmed	Inflammation-induced increase in nicotinic acetylcholine receptor current in cutaneous nociceptive DRG neurons from the adult rat.	CHRFAM7A CHRNA7	1.87e-06	2	48	2	25453771
Interaction	UROS interactions	ATG7 ATG3 CTU1	1.64e-05	21	48	3	int:UROS
Interaction	NTN5 interactions	LRP2 FRAS1 FBN1	2.48e-05	24	48	3	int:NTN5
Cytoband	3p21.1	CHDH STAB1	8.97e-04	42	48	2	3p21.1
Cytoband	9p13.3	RUSC2 NFX1	2.83e-03	75	48	2	9p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	PLXNB1 CHDH STAB1	4.44e-03	316	48	3	chr3p21
Cytoband	Ensembl 112 genes in cytogenetic band chr15q13	CHRFAM7A CHRNA7	4.96e-03	100	48	2	chr15q13
GeneFamily	Laminin subunits	LAMB4 LAMC2	1.62e-04	12	29	2	626
GeneFamily	Autophagy related	ATG7 ATG3	1.27e-03	33	29	2	1022
Coexpression	NABA_MATRISOME	CHRD LAMB4 LAMC2 FRAS1 FBN1 ADAMTS5 COL25A1 CLEC10A INHA MUC5AC PXDNL PLXNB1 SLIT1	2.53e-08	1026	48	13	M5889
Coexpression	NABA_CORE_MATRISOME	LAMB4 LAMC2 FRAS1 FBN1 COL25A1 PXDNL SLIT1	6.61e-07	275	48	7	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMB4 LAMC2 FRAS1 FBN1 PXDNL SLIT1	1.53e-06	196	48	6	M3008
Coexpression	NABA_MATRISOME	CHRD LAMC2 FRAS1 FBN1 ADAMTS5 COL25A1 CLEC10A INHA MUC5AC PLXNB1 SLIT1	1.58e-06	1008	48	11	MM17056
Coexpression	QI_PLASMACYTOMA_DN	LAMC2 TRIP6 MATK SVIL	3.15e-05	98	48	4	M1852
Coexpression	QI_PLASMACYTOMA_DN	LAMC2 TRIP6 MATK SVIL	3.41e-05	100	48	4	MM775
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DPYD FBN1 COL25A1 PTPRD SVIL	1.70e-06	186	48	5	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FBN1 ADAMTS5 COL25A1 PTPRD SVIL	1.74e-06	187	48	5	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 FRAS1 PTPRD AOPEP SVIL	1.98e-06	192	48	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMC2 FRAS1 OSBP2 CLEC10A	2.53e-05	158	48	4	c8af8964a140acb2987e3b4906d72c546108d229
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLEC10A SPINT1 MATK SIAH3	2.99e-05	165	48	4	1c630f9ecde2e0243922a2be4b1ab5adcfcb0893
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRP2 CHRD FRAS1 PTPRD	3.14e-05	167	48	4	c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRP2 CHRD FRAS1 PTPRD	3.14e-05	167	48	4	351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TET2 ADAMTS5 INHA DISP1	3.52e-05	172	48	4	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS5 CHRFAM7A CHRNA7 SIAH3	3.94e-05	177	48	4	fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell	facs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DISP3 PTPRD PLXNB1 ADGRB1	4.20e-05	180	48	4	c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCell	facs-Marrow-B-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DISP3 PTPRD PLXNB1 ADGRB1	4.20e-05	180	48	4	07ac979b21be2425294d9818c48b5a1e6f014c19
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 CHRD FBN1 ADAMTS5	4.39e-05	182	48	4	b7d532feb73167e05475855061b35a209583f44c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 CHRD FBN1 ADAMTS5	4.39e-05	182	48	4	af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRP2 FRAS1 PTPRD CHDH	4.48e-05	183	48	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 DISP3 FRAS1 PTPRD	4.58e-05	184	48	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 DISP3 FRAS1 PTPRD	4.58e-05	184	48	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 DISP3 FRAS1 PTPRD	4.58e-05	184	48	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FBN1 ADAMTS5 COL25A1 SVIL	4.67e-05	185	48	4	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CHRD ADAMTS5 PXDNL SIAH3	4.77e-05	186	48	4	948815663c212c4311329d503b5991cbbbff9808
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 LRP2 PTPRD CHDH	4.77e-05	186	48	4	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 ADAMTS5 COL25A1 PTPRD	4.98e-05	188	48	4	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	KLHL29 LRP2 PTPRD CHDH	5.08e-05	189	48	4	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPYD CLEC10A ATG7 STAB1	5.08e-05	189	48	4	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FBN1 COL25A1 PTPRD CHDH	5.18e-05	190	48	4	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	LAMC2 FBN1 ADAMTS5 PTPRD	5.18e-05	190	48	4	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	DPYD CLEC10A ATG7 STAB1	5.29e-05	191	48	4	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LRP2 FRAS1 SPINT1 SLIT1	5.29e-05	191	48	4	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 LRP2 PTPRD AOPEP	5.29e-05	191	48	4	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TET2 MATK CHDH SLIT1	5.29e-05	191	48	4	54f07e4de61735051498846afb44b1798bed8144
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LRP2 FRAS1 SPINT1 MUC5AC	5.40e-05	192	48	4	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CHRD ADAMTS5 PXDNL ADGRB1	5.40e-05	192	48	4	5000440dc1ed17e7474d340921bdff945646f27e
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 ADAMTS5 PTPRD INHA	5.51e-05	193	48	4	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	E15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CHRD FBN1 ADAMTS5 SVIL	5.51e-05	193	48	4	e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 FRAS1 PTPRD AOPEP	5.62e-05	194	48	4	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	DPYD FBN1 ADAMTS5 PTPRD	5.73e-05	195	48	4	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP2 LAMC2 SPINT1 CHDH	5.73e-05	195	48	4	4d7ca21f14730e1b6d0473bc1a11aa626db948f3
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell-epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP2 LAMC2 SPINT1 CHDH	5.73e-05	195	48	4	8727554ef047ca7f1d4b888a8468f148c64a6918
ToppCell	droplet-Trachea-nan-3m-Epithelial-epithelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMC2 SPINT1 CHDH	5.73e-05	195	48	4	9f0ee826d4f0997aee8d63284ed24549bbdf6a28
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	TET2 DPYD ATG7 STAB1	5.85e-05	196	48	4	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TET2 DPYD CLEC10A STAB1	5.85e-05	196	48	4	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TET2 DPYD ATG7 STAB1	5.97e-05	197	48	4	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 PTPRD PXDNL SVIL	5.97e-05	197	48	4	2744cc94883c5d0424677cf5093bbab622933e9b
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CHRD FBN1 ADAMTS5 PXDNL	5.97e-05	197	48	4	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TET2 DPYD CLEC10A ATG7	5.97e-05	197	48	4	1eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC2 FRAS1 SPINT1 CHDH	6.08e-05	198	48	4	edf3e1c2be9df5690492b9c8fc25e7e48ed5c92c
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	TET2 DPYD CLEC10A STAB1	6.20e-05	199	48	4	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHRD ADAMTS5 PXDNL AOPEP	6.20e-05	199	48	4	aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCell	Healthy_Control-Myeloid-Macrophages-FCN1-SPP1+\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CLEC10A SLC26A11 MATK STAB1	6.20e-05	199	48	4	7437bc48a803ab8f153e5516a0aa0391ae3d97c7
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL29 FZD8 FBN1 PTPRD	6.33e-05	200	48	4	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	(6)_Stroma\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	CHRD FBN1 ADAMTS5 SLIT1	6.33e-05	200	48	4	f9baef67dde62f1c161a9408a78f635ea70ea9d3
ToppCell	(6)_Stroma\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	CHRD FBN1 ADAMTS5 SLIT1	6.33e-05	200	48	4	f0818821c495022569aef2c1886d9f2446dc027e
ToppCell	Mild-Myeloid-Macrophages-\|Mild / Condition, Lineage, Cell class and cell subclass	KLHL29 NMUR1 CTU1	3.08e-04	122	48	3	b837456a6a236add2c0005cb3ca71568d631014e
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Myxofibrosarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	FBN1 ADAMTS5 PXDNL	3.15e-04	123	48	3	12b87d06e62f142e18424aae5c87454e78e713f0
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-1\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	NMUR1 EZH1 AOPEP	3.23e-04	124	48	3	57f3335f751868a768934c757b06a6378148dc9e
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	SLC2A10 FRAS1 INHA	3.79e-04	131	48	3	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_smooth_muscle-like\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DPYD CTU1 DISP1	3.88e-04	132	48	3	9633653dba1edee47d915212fb6e68426da49de5
ToppCell	(02)_Cycling_Basal_(regeneration)-(3)_72hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	SLC2A10 FBN1 PKD1L1	3.96e-04	133	48	3	32c6a00671af309c4b0b90e93549733729684c61
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	MUC5AC CTU1 CHRNA7	4.32e-04	137	48	3	25b5370b63644351efddb8749ef174beca0581cd
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cpa6_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMC2 FRAS1 CLEC10A	4.80e-04	142	48	3	84742a7e35bab09ee1cca80cfe120b613d6aed6a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Whrn_Tox2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMC2 FRAS1 CLEC10A	4.90e-04	143	48	3	36ce6f163fb33141c86288086c354b91853fad25
ToppCell	facs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DISP3 CLEC10A CHDH	5.31e-04	147	48	3	9d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCell	facs-Marrow-B-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DISP3 CLEC10A CHDH	5.31e-04	147	48	3	38552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CLEC10A CHRFAM7A STAB1	5.52e-04	149	48	3	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL25A1 CHRNA7 SLIT1	5.63e-04	150	48	3	47ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLEC10A CHRFAM7A STAB1	5.63e-04	150	48	3	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	Basal_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FRAS1 INHA PLXNB1	5.85e-04	152	48	3	72499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|GI_small-bowel / Manually curated celltypes from each tissue	LRP2 SPINT1 MATK	6.19e-04	155	48	3	1c67f58ed79331addbc012dab0cb09a7f350aedb
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DISP3 CHRNA7 SIAH3	6.19e-04	155	48	3	105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell	severe_COVID-19-cDC\|World / disease group, cell group and cell class (v2)	FBN1 CLEC10A SPINT1	6.31e-04	156	48	3	0a7e18ed8e13261c405eb6b9a183e99d8e1aac37
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMC2 FRAS1 COL25A1	6.43e-04	157	48	3	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Batf3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMC2 FRAS1 COL25A1	6.43e-04	157	48	3	921805932f7974d37aed547861d555b07f30aba6
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLEC10A MATK STAB1	6.54e-04	158	48	3	9a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLEC10A MATK STAB1	6.54e-04	158	48	3	2438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCell	10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-\|Lung / Manually curated celltypes from each tissue	SLC2A10 PTPRD MATK	6.67e-04	159	48	3	595643e9433265308e5aab7f906229025701cf6a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CHRFAM7A CHRNA7 SVIL	7.16e-04	163	48	3	725927926a07308013cf0c527fb6c54e99189ac0
ToppCell	severe-HSPC\|severe / disease stage, cell group and cell class	FBN1 CHRFAM7A ADGRB1	7.42e-04	165	48	3	acd837d88ad3786c263f74651a6c0e02fa2fa2c5
ToppCell	15-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	LAMC2 ADAMTS5 SIAH3	7.42e-04	165	48	3	531804467601e1ee1f771cffa21501f6d464ae10
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 MUC5AC SVIL	7.42e-04	165	48	3	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LRP2 FZD8 CHRFAM7A	7.55e-04	166	48	3	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	367C-Fibroblasts-Fibroblast-F\|367C / Donor, Lineage, Cell class and subclass (all cells)	CHRD FBN1 ADAMTS5	7.55e-04	166	48	3	2887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NMUR1 FRAS1 MATK	7.55e-04	166	48	3	61e4b2d2db093e64f7354b534aa8571803a3bd44
ToppCell	10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-\|blood / Manually curated celltypes from each tissue	FRAS1 MATK CHRNA7	7.55e-04	166	48	3	ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCell	droplet-Lung-LUNG-1m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC10A SPINT1 MATK	7.55e-04	166	48	3	c215c4aede38d355d35fd26cd7ef2c19efecd0e6
ToppCell	367C-Fibroblasts-Fibroblast-F-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CHRD FBN1 ADAMTS5	7.55e-04	166	48	3	1cc291a04f4144abba4aca7badeb7776db05d903
ToppCell	5'-Adult-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC2 DPYD CTU1	7.55e-04	166	48	3	0b4e1d879c61be9d18d7aac51e5115f103f51209
ToppCell	Basal_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	FRAS1 COL25A1 AOPEP	7.55e-04	166	48	3	aea2ae12e4746149ebc6da063ef694381c098f80
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHRD MATK SLIT1	7.68e-04	167	48	3	3dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHRD MATK SLIT1	7.68e-04	167	48	3	95b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHRD MATK SLIT1	7.68e-04	167	48	3	9480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLEC10A SPINT1 MATK	7.68e-04	167	48	3	9526e2c7673d569d04e0728a2526318e67432e0a
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LRP2 LAMC2 SPINT1	7.68e-04	167	48	3	25af48c640e67848594f5902867ba325fc105da4
ToppCell	normal_Lung-Fibroblasts-Mesothelial_cells\|Fibroblasts / Location, Cell class and cell subclass	LRP2 MUC5AC SIAH3	7.68e-04	167	48	3	892a2dc83ab5de5a1016402f8e95d2aabf651326
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TET2 MATK CHDH	7.82e-04	168	48	3	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	droplet-Lung-LUNG-30m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC10A MUC5AC CHDH	7.82e-04	168	48	3	e156297a7515e785a9e79a9676700bd3a9d92b98
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLEC10A SPINT1 SIAH3	7.82e-04	168	48	3	d6078e3a79d315d6090906e171a7d67a9206b2c7
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC10A MUC5AC CHDH	7.82e-04	168	48	3	32e0bc0873baa13027241063283ef26d2aab56f5
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CHRD LAMC2 DISP1	7.82e-04	168	48	3	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRP2 NMUR1 MATK	7.82e-04	168	48	3	b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 ADAMTS5 SIAH3	7.95e-04	169	48	3	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC10A MUC5AC CHDH	7.95e-04	169	48	3	7962165cab84af73d20b56eb70b1ed87c94025ef
Disease	cognitive disorder (implicated_via_orthology)	CHRFAM7A CHRNA7	3.71e-05	6	47	2	DOID:1561 (implicated_via_orthology)
Disease	rheumatoid arthritis (biomarker_via_orthology)	CHRFAM7A CHRNA7	3.71e-05	6	47	2	DOID:7148 (biomarker_via_orthology)
Disease	pneumococcal bacteremia	LAMB4 SIAH3	1.35e-04	11	47	2	EFO_1001925
Disease	nicotine dependence (implicated_via_orthology)	CHRFAM7A CHRNA7	1.62e-04	12	47	2	DOID:0050742 (implicated_via_orthology)
Disease	myelodysplastic syndrome (implicated_via_orthology)	TET2 ATG7	2.57e-04	15	47	2	DOID:0050908 (implicated_via_orthology)
Disease	bipolar disorder, sex interaction measurement	SLIT1 ADGRB1	3.74e-04	18	47	2	EFO_0008343, MONDO_0004985
Disease	S-warfarin to R-warfarin ratio measurement	DPYD ADAMTS5 SVIL	4.73e-04	95	47	3	EFO_0803331
Disease	waist-hip ratio	KLHL29 TET2 DPYD PTPRD EZH1 ATG7 RSBN1L STAB1	6.44e-04	1226	47	8	EFO_0004343
Disease	peak expiratory flow	KLHL29 TET2 SLC2A10 ADAMTS5 SVIL	1.15e-03	498	47	5	EFO_0009718
Disease	liver cirrhosis (biomarker_via_orthology)	FBN1 SPINT1	1.35e-03	34	47	2	DOID:5082 (biomarker_via_orthology)
Disease	response to radiation, prostate carcinoma, erectile dysfunction	AOPEP NFX1	1.60e-03	37	47	2	EFO_0001663, EFO_0004234, GO_0009314
Disease	Parkinson disease, disease progression measurement	KLHL29 PTPRD	1.77e-03	39	47	2	EFO_0008336, MONDO_0005180
Disease	invasive ductal carcinoma (is_marker_for)	INHA ADGRB1	1.86e-03	40	47	2	DOID:3008 (is_marker_for)
Disease	colorectal cancer, endometrial neoplasm	TET2 AOPEP	2.05e-03	42	47	2	EFO_0004230, MONDO_0005575
Disease	neuritic plaque measurement	CHRFAM7A PXDNL CHRNA7 SLIT1	2.30e-03	349	47	4	EFO_0006798

Protein segments in the cluster

Peptide	Gene	Start	Entry
HGRVCMAPPGCLLSS	DISP3	946	Q9P2K9
RSSHPCGIMQTPCAC	ADGRB1	201	O14514
CSLMPCPPNGKSFRH	ADAMTS5	616	Q9UNA0
GSKAGMCACHSPLPS	DPYD	316	Q12882
ACKFGMPEPCHIPVT	AOPEP	71	Q8N6M6
TPLCGGHREPCVMRT	APEX2	466	Q9UBZ4
MATPRPCADGPCCSH	ANKRD39	1	Q53RE8
PAAPSALASCCMQPH	DISP1	106	Q96F81
PPMCSVHPCRHAEVM	ATG3	256	Q9NT62
HCVPTPDSGVVCGRM	CHRNA7	396	P36544
HPSCTCKMGQPSDPT	CHDH	511	Q8NE62
AASMGRCSVPECPFP	PCDHB18P	666	Q96TA0
PPLLMRHGQCVPTCG	FRAS1	486	Q86XX4
PEGCPGPVHVLMSSC	MATK	446	P42679
HVPCRGPVPDSAVCM	NMUR1	206	Q9HB89
MGHSPPVLPLCASVS	SLC2A10	1	O95528
PCGSDHTPSPMASRV	PLXNB1	376	O43157
TPAEQHCARTMPPCA	COL25A1	21	Q9BXS0
CTTPRADCGHPCMAP	NFX1	856	Q12986
PCMAPCHTSSPCPVT	NFX1	866	Q12986
GCPTRPPGMCHSDEF	LRP2	1221	P98164
GRTGHMCPFTCPADK	MUC5AC	5206	P98088
VVPCLSCHTAAPGMS	OSBP2	26	Q969R2
HCVPTPDSGVVCGRM	CHRFAM7A	306	Q494W8
CTNDPPCFPMNTRHA	PXDNL	836	A1KZ92
CCPVCRDRGMPSDSP	PXDNL	1446	A1KZ92
APCEPGCQCRAPMVS	FZD8	226	Q9H461
DMSAPTPARCCPAIG	ATG7	71	O95352
CEMCPAQPHPCRRGF	FBN1	221	P35555
MPAPPCASCHAARAA	CTU1	1	Q7Z7A3
PCCAALPGTMRPLHV	INHA	326	P05111
RCSCHASGVSPMECP	LAMB4	1021	A4D0S4
PCPCHNGFSCSVMPE	LAMC2	461	Q13753
PCGVPACSHVPMRSA	CRIPAK	111	Q8N1N5
CPCGVPACSHVPMRS	CRIPAK	141	Q8N1N5
MGKSHCCPPHTQAPS	PKD1L1	2101	Q8TDX9
CNPPDAGPMVVHCSA	PTPRD	1541	P23468
PLDEGTCCSHSLPPM	RUSC2	586	Q8N2Y8
MAEPPSPVHCVAAAA	RSBN1L	1	Q6PCB5
CSGGTHPVMARLPSP	SVIL	756	O95425
GLHANPVTPCLCMCP	SIAH3	96	Q8IW03
PHCPSVCVPVHSEML	CLEC10A	136	Q8IUN9
HPSVPPFGEMSCITC	CHRD	886	Q9H2X0
SRAETQPMAPHCPAG	TRMO	301	Q9BU70
APRCSVCGGAIMPEP	TRIP6	396	Q15654
PGMAPSACCCSPAAL	SLC26A11	16	Q86WA9
GPSMERRHPVCSGTC	SPINT1	321	O43278
HPDRPCDSTCPCIMT	EZH1	526	Q92800
GQPPPCHSDAMCTDL	STAB1	2186	Q9NY15
ICQPNATPGPMCHCE	SLIT1	1351	O75093
GCKPHACMHTAPPEN	TET2	986	Q6N021
TLLPHMPCPVFRHGC	KLHL29	851	Q96CT2