Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF21B KIF18A KIF21A KIF4A KIF3A DNAH1 KIF3B KIF28P KIF4B KIF3C KIF17

2.60e-127014311GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF21B KIF18A KIF21A KIF4A KIF3A DNAH1 KIF3B KIF28P KIF4B KIF3C KIF17

8.57e-1011814311GO:0003774
GeneOntologyMolecularFunctionmicrotubule binding

KIF21B KIF18A KIF21A KIF4A TUBGCP2 CCDC61 KIF3A CEP350 KIF3B MAP1S KIF28P KIF4B KIF3C KIF17

4.80e-0830814314GO:0008017
GeneOntologyMolecularFunctionATP-dependent activity

KIF21B KIF18A CCT3 KIF21A KIF4A MCM7 ABCA7 ATP8B2 KIF3A DNAH1 KIF3B RALBP1 KIF28P HELZ KIF4B KIF3C KIF17 RAD54L

4.22e-0761414318GO:0140657
GeneOntologyMolecularFunctiontubulin binding

KIF21B KIF18A KIF21A KIF4A TUBGCP2 CCDC61 KIF3A CEP350 KIF3B MAP1S KIF28P KIF4B KIF3C KIF17

2.52e-0642814314GO:0015631
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF18A KIF3A KIF3B KIF17

5.58e-06171434GO:0008574
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21B KIF18A CCT3 KIF21A MCM7 ABCA7 ATP8B2 KIF3A KIF3B KIF28P KIF3C KIF17 RAD54L

1.77e-0544114313GO:0016887
GeneOntologyMolecularFunctionpseudophosphatase activity

SBF1 STYXL1

1.52e-0431432GO:0001691
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C1 AKR1C2

3.03e-0441432GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C1 AKR1C2

3.03e-0441432GO:0045703
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

3.03e-0441432GO:0047718
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C1 AKR1C2

3.03e-0441432GO:0047743
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF21B KIF18A CORO2A KIF21A TRPC5 KIF4A TUBGCP2 FMNL2 CCDC61 KIF3A CEP350 KIF3B MAP1S KIF28P KIF4B KIF3C PLEC KIF17 UNC13A

3.23e-04109914319GO:0008092
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C1 AKR1C2

5.02e-0451432GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C1 AKR1C2

5.02e-0451432GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C1 AKR1C2

5.02e-0451432GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C1 AKR1C2

5.02e-0451432GO:0047006
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C1 AKR1C2

5.02e-0451432GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C1 AKR1C2

5.02e-0451432GO:0047086
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C1 AKR1C2

5.02e-0451432GO:0047787
GeneOntologyMolecularFunctionintraciliary transport particle B binding

KIF3A KIF3B

7.50e-0461432GO:0120170
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C1 AKR1C2

7.50e-0461432GO:0045550
GeneOntologyMolecularFunctionGTPase activator activity

RALGAPA1 RASA3 ARHGEF12 TBC1D22B RIN1 FAM13A RALBP1 PREX1

9.19e-042791438GO:0005096
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C1 AKR1C2

1.04e-0371432GO:0072582
GeneOntologyMolecularFunctionphosphatase regulator activity

URI1 SHOC2 SBF1 STYXL1 PPP1R16A

1.33e-031131435GO:0019208
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C1 AKR1C2

1.39e-0381432GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C1 AKR1C2

1.39e-0381432GO:0047023
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCA7 ATP8B2

1.39e-0381432GO:0090554
GeneOntologyMolecularFunctionenone reductase activity

AKR1C1 AKR1C2

1.39e-0381432GO:0035671
GeneOntologyMolecularFunctionmonooxygenase activity

NLRP11 CYP21A2 CYP27A1 AKR1C1 AKR1C2

1.43e-031151435GO:0004497
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C1 AKR1C2

1.77e-0391432GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C1 AKR1C2

1.77e-0391432GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C1 AKR1C2

2.21e-03101432GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C1 AKR1C2

2.21e-03101432GO:0032052
GeneOntologyMolecularFunctionphosphoprotein phosphatase activity

LRRIQ4 MTMR4 PTPN13 SBF1 LRRD1 PHLPP2

2.43e-031891436GO:0004721
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC4 TRPC5

3.21e-03121432GO:0015279
GeneOntologyMolecularFunctioncargo receptor activity

STAB2 INSR ABCA7 LRP2

3.26e-03851434GO:0038024
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RALGAPA1 RASA3 RGL3 ARHGEF12 TBC1D22B RIN1 FAM13A SBF1 RALBP1 PREX1

3.60e-0350714310GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RALGAPA1 RASA3 RGL3 ARHGEF12 TBC1D22B RIN1 FAM13A SBF1 RALBP1 PREX1

3.60e-0350714310GO:0030695
GeneOntologyMolecularFunctionpoly(A)-specific ribonuclease activity

CNOT6 CNOT6L

3.77e-03131432GO:0004535
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

INSR LRP2

3.77e-03131432GO:0031994
GeneOntologyMolecularFunctionglycosphingolipid binding

CEL LAMA1

3.77e-03131432GO:0043208
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF21B KIF18A CCT3 KIF21A MCM7 ABCA7 ATP8B2 KIF3A KIF3B KIF28P KIF3C KIF17 RAD54L

3.82e-0377514313GO:0017111
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C1 AKR1C2

4.38e-03141432GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C1 AKR1C2

4.38e-03141432GO:0001758
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC4 TRPC5

4.38e-03141432GO:0070679
GeneOntologyBiologicalProcessmicrotubule-based movement

KIF21B KIF18A KIF21A KIF4A NPHP4 KIF3A DNAH1 KIF3B CELSR2 MAP1S KIF28P KIF4B TAC3 KIF3C KIF17

1.49e-0649314115GO:0007018
GeneOntologyBiologicalProcessdendritic transport

KIF21B KIF3A KIF3B KIF17

7.49e-06191414GO:0098935
GeneOntologyBiologicalProcessanterograde dendritic transport of neurotransmitter receptor complex

KIF3A KIF3B KIF17

1.07e-0571413GO:0098971
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

CREB1 AKR1C1 AKR1C2

4.96e-05111413GO:2000224
GeneOntologyBiologicalProcessanterograde dendritic transport

KIF3A KIF3B KIF17

6.58e-05121413GO:0098937
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

KIF18A STAG1 KIF4A CCDC61 KLHL22 KIF3B BUB1B KIF4B

1.07e-042121418GO:0000070
GeneOntologyBiologicalProcessmicrotubule-based process

KIF21B KIF18A STAG1 KIF21A KIF4A TUBGCP2 NPHP4 CCDC61 KIF3A DNAH1 CEP350 KIF3B CELSR2 MAP1S KIF28P KIF4B TAC3 KIF3C KIF17

1.10e-04105814119GO:0007017
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

TANC2 KIF21B KIF4A KIF3A KIF3B MAP1S KIF28P KIF17

1.62e-042251418GO:0030705
GeneOntologyBiologicalProcesstestosterone biosynthetic process

CREB1 AKR1C1 AKR1C2

1.64e-04161413GO:0061370
GeneOntologyBiologicalProcessC21-steroid hormone metabolic process

CYP21A2 AKR1C1 AKR1C2 EDNRB

2.51e-04451414GO:0008207
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C1 AKR1C2

2.76e-0441412GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C1 AKR1C2

2.76e-0441412GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C1 AKR1C2

2.76e-0441412GO:0071395
GeneOntologyBiologicalProcessdense core granule priming

UNC13C UNC13A

2.76e-0441412GO:0061789
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C1 AKR1C2

2.76e-0441412GO:0008208
GeneOntologyBiologicalProcessorganelle assembly

STAG1 FBF1 KIF4A TBC1D22B TUBGCP2 CCDC61 KIF3A DNAH1 CNOT6 CEP350 KIF3B CNOT6L CELSR2 STYXL1 KIF4B PRKDC PLEC ULK2 VPS37D

2.78e-04113814119GO:0070925
GeneOntologyBiologicalProcessmitotic nuclear division

KIF18A STAG1 INSR KIF4A CCDC61 KLHL22 KIF3B BUB1B KIF4B

3.31e-043161419GO:0140014
GeneOntologyBiologicalProcessmicrotubule-based transport

KIF21B KIF4A KIF3A DNAH1 KIF3B MAP1S KIF28P KIF17

3.57e-042531418GO:0099111
GeneOntologyBiologicalProcesssister chromatid segregation

KIF18A STAG1 KIF4A CCDC61 KLHL22 KIF3B BUB1B KIF4B

3.67e-042541418GO:0000819
GeneOntologyBiologicalProcesstransport along microtubule

KIF21B KIF4A KIF3A KIF3B MAP1S KIF28P KIF17

4.19e-041971417GO:0010970
GeneOntologyBiologicalProcessmitotic spindle assembly

STAG1 KIF4A CCDC61 KIF3B KIF4B

4.24e-04921415GO:0090307
GeneOntologyBiologicalProcessmembraneless organelle assembly

STAG1 KIF4A TUBGCP2 CCDC61 CNOT6 KIF3B CNOT6L STYXL1 KIF4B PRKDC PLEC

4.31e-0447514111GO:0140694
GeneOntologyBiologicalProcessprogesterone metabolic process

CYP21A2 AKR1C1 AKR1C2

4.38e-04221413GO:0042448
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C1 AKR1C2

4.58e-0451412GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C1 AKR1C2

4.58e-0451412GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C1 AKR1C2

4.58e-0451412GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C1 AKR1C2

4.58e-0451412GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C1 AKR1C2

4.58e-0451412GO:0120256
GeneOntologyBiologicalProcessvein smooth muscle contraction

HTR7 EDNRB

4.58e-0451412GO:0014826
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2

4.58e-0451412GO:1900053
GeneOntologyBiologicalProcessalcohol metabolic process

CEL CYP27A1 CHKA AKR1C1 AKR1C2 EDNRB MYOF P2RY1 LRP2 MVK

5.49e-0441214110GO:0006066
GeneOntologyBiologicalProcessaxo-dendritic transport

KIF21B KIF4A KIF3A KIF3B KIF17

5.67e-04981415GO:0008088
GeneOntologyBiologicalProcesspositive regulation of glycogen metabolic process

ESRRB INSR PHKG2

5.70e-04241413GO:0070875
GeneOntologyBiologicalProcessmitotic spindle organization

STAG1 KIF4A CCDC61 KIF3B MAP1S KIF4B

6.07e-041511416GO:0007052
GeneOntologyBiologicalProcessmicrotubule anchoring

KIF3A CEP350 MAP1S

6.44e-04251413GO:0034453
GeneOntologyBiologicalProcessspindle assembly

STAG1 KIF4A TUBGCP2 CCDC61 KIF3B KIF4B

6.50e-041531416GO:0051225
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C1 AKR1C2

6.84e-0461412GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C1 AKR1C2

6.84e-0461412GO:0016095
GeneOntologyBiologicalProcessplus-end-directed vesicle transport along microtubule

KIF3A KIF3B

6.84e-0461412GO:0072383
GeneOntologyBiologicalProcessnegative regulation of synaptic plasticity

RIN1 UNC13C

6.84e-0461412GO:0031914
GeneOntologyBiologicalProcesspositive regulation of cytoplasmic mRNA processing body assembly

CNOT6 CNOT6L

6.84e-0461412GO:0010606
GeneOntologyCellularComponentmicrotubule associated complex

KIF21B KIF18A KIF21A KIF4A KIF3A DNAH1 KIF3B MAP1S KIF28P KIF4B KIF3C KIF17

1.06e-0916114212GO:0005875
GeneOntologyCellularComponentkinesin complex

KIF21B KIF18A KIF21A KIF3A KIF3B KIF28P KIF3C KIF17

1.33e-09491428GO:0005871
GeneOntologyCellularComponentmicrotubule

KIF21B KIF18A CCT3 KIF21A KIF4A TUBGCP2 KIF3A KLHL22 DNAH1 RASSF5 KIF3B MAP1S KIF28P KIF4B KIF3C KIF17

7.19e-0753314216GO:0005874
GeneOntologyCellularComponentaxon

TANC2 KIF21B EXOC6 HTR7 KIF21A TRPC5 INSR KIF4A CASR CREB1 KIF3A KIF3B LRP2 UNC13C KIF3C PLEC PREX1 ALK UNC13A

9.82e-0689114219GO:0030424
GeneOntologyCellularComponentspindle

KIF18A STAG1 FBF1 KIF4A TUBGCP2 KIF3A KLHL22 CEP350 KIF3B MAP1S RALBP1 BUB1B PHLPP2

2.03e-0547114213GO:0005819
GeneOntologyCellularComponentspindle microtubule

KIF18A KIF4A KIF3A KLHL22 KIF3B MAP1S

2.66e-05861426GO:0005876
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KIF21B KIF18A CCT3 KIF21A FBF1 KIF4A TUBGCP2 KIF3A KLHL22 DNAH1 RASSF5 KIF3B MAP1S KIF28P KIF4B KIF3C PLEC KIF17

3.94e-0589914218GO:0099513
GeneOntologyCellularComponentkinesin II complex

KIF3A KIF3B

1.37e-0431422GO:0016939
GeneOntologyCellularComponentdendrite

TANC2 KIF21B URI1 HTR7 KIF21A TRPC5 INSR RIN1 KIF3B MAP1S P2RY1 LRP2 KIF3C PLEC KIF17 PREX1

2.44e-0485814216GO:0030425
GeneOntologyCellularComponentdendritic tree

TANC2 KIF21B URI1 HTR7 KIF21A TRPC5 INSR RIN1 KIF3B MAP1S P2RY1 LRP2 KIF3C PLEC KIF17 PREX1

2.51e-0486014216GO:0097447
GeneOntologyCellularComponentATF4-CREB1 transcription factor complex

CREB1 CREM

2.72e-0441422GO:1990589
GeneOntologyCellularComponentintegrator complex

ESRRB INTS2 INTS4

3.73e-04211423GO:0032039
GeneOntologyCellularComponentdistal axon

KIF21B EXOC6 HTR7 TRPC5 CASR LRP2 UNC13C KIF3C PREX1 UNC13A

7.95e-0443514210GO:0150034
GeneOntologyCellularComponentneuron projection cytoplasm

KIF4A KIF3A KIF3B KIF3C KIF17

9.31e-041101425GO:0120111
GeneOntologyCellularComponentsupramolecular fiber

KIF21B KIF18A CCT3 KIF21A FBF1 KIF4A TUBGCP2 KIF3A KLHL22 DNAH1 RASSF5 KIF3B MAP1S KIF28P KIF4B KIF3C PLEC KIF17

1.07e-03117914218GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KIF21B KIF18A CCT3 KIF21A FBF1 KIF4A TUBGCP2 KIF3A KLHL22 DNAH1 RASSF5 KIF3B MAP1S KIF28P KIF4B KIF3C PLEC KIF17

1.16e-03118714218GO:0099081
GeneOntologyCellularComponentsomatodendritic compartment

TANC2 KIF21B URI1 HTR7 KIF21A TRPC5 INSR CASR KIF3A RIN1 KIF3B MAP1S P2RY1 LRP2 KIF3C PLEC KIF17 PREX1

1.69e-03122814218GO:0036477
GeneOntologyCellularComponentcentrosome

KIF18A FBF1 UBR4 TUBGCP2 NPHP4 CCDC61 KIF3A KLHL22 CEP350 MYOF KIF3B MAP1S BUB1B

2.30e-0377014213GO:0005813
DomainKinesin_motor_CS

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

1.87e-11411429IPR019821
DomainKinesin-like_fam

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

2.98e-11431429IPR027640
Domain-

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

3.72e-114414293.40.850.10
DomainKinesin

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

3.72e-11441429PF00225
DomainKISc

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

3.72e-11441429SM00129
DomainKINESIN_MOTOR_1

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

3.72e-11441429PS00411
DomainKinesin_motor_dom

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

3.72e-11441429IPR001752
DomainKINESIN_MOTOR_2

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C KIF17

3.72e-11441429PS50067
DomainLeu-rich_rpt

NLRP11 VASN LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 SNRPA1 LRRD1 ADGRA3 PHLPP2 LRRC74B

2.01e-0827114214IPR001611
DomainL_dom-like

NLRP11 VASN INSR LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 SNRPA1 LRRD1 ADGRA3 PHLPP2 LRRC74B

3.10e-0832814215IPR032675
DomainLRR

VASN LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 SNRPA1 LRRD1 ADGRA3 PHLPP2

4.45e-0820114212PS51450
DomainLRR_8

VASN LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 LRRD1 ADGRA3 PHLPP2

7.77e-0817114211PF13855
DomainLRR_TYP

VASN LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 LRRD1 ADGRA3 PHLPP2

1.10e-0717714211SM00369
DomainLeu-rich_rpt_typical-subtyp

VASN LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 LRRD1 ADGRA3 PHLPP2

1.10e-0717714211IPR003591
DomainLRR_1

VASN LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 SNRPA1 LRRD1 ADGRA3 PHLPP2

1.14e-0721914212PF00560
Domain-

NLRP11 VASN LRRIQ4 TLR9 SHOC2 CNOT6 CNOT6L LRIG1 LRRC1 SNRPA1 LRRD1 ADGRA3 PHLPP2 LRRC74B

1.64e-07321142143.80.10.10
DomainpKID

CREB1 CREM

1.71e-0431422PF02173
DomainKID

CREB1 CREM

1.71e-0431422PS50953
DomainUnc-13

UNC13C UNC13A

1.71e-0431422IPR027080
DomainCoactivator_CBP_pKID

CREB1 CREM

1.71e-0431422IPR003102
DomainLeuzip_CREB

CREB1 CREM

3.41e-0441422IPR001630
DomainMunc13_dom-2

UNC13C UNC13A

5.65e-0451422IPR014772
DomainMHD2

UNC13C UNC13A

5.65e-0451422PS51259
DomainMunc13_subgr_dom-2

UNC13C UNC13A

5.65e-0451422IPR019558
DomainMembr_traf_MHD

UNC13C UNC13A

5.65e-0451422PF10540
DomainDUF1041

UNC13C UNC13A

5.65e-0451422SM01145
DomainP-loop_NTPase

TANC2 KIF21B KIF18A KIF21A KIF4A MCM7 ABCA7 KIF3A DNAH1 KIF3B CHST4 HELZ KIF4B KIF3C KIF17 RAD54L

7.31e-0484814216IPR027417
DomainTRP_2

TRPC4 TRPC5

8.44e-0461422PF08344
DomainTRP_dom

TRPC4 TRPC5

8.44e-0461422IPR013555
DomainARM-type_fold

RALGAPA1 STAG1 UBR4 HUWE1 FMNL2 HEATR6 INTS4 UTP20 PRKDC

1.16e-033391429IPR016024
DomainMunc13_1

UNC13C UNC13A

1.18e-0371422IPR014770
DomainMHD1

UNC13C UNC13A

1.18e-0371422PS51258
DomainTRPC_channel

TRPC4 TRPC5

1.18e-0371422IPR002153
DomainDUF1041

UNC13C UNC13A

1.18e-0371422PF06292
DomainCAPS_dom

UNC13C UNC13A

1.18e-0371422IPR010439
DomainEGF_LAM_2

STAB2 LAMA1 CELSR2

1.50e-03301423PS50027
DomainEGF_LAM_1

STAB2 LAMA1 CELSR2

1.50e-03301423PS01248
DomainRA

RGL3 RASSF5 RIN1

1.65e-03311423SM00314
DomainLRRCT

VASN LRIG1 ADGRA3

1.82e-03321423PF01463
DomainHEAT_REPEAT

HEATR6 INTS4 UTP20 PRKDC

1.99e-03701424PS50077
DomainPrefoldin

KIF21B URI1 KIF21A KIF4A

2.21e-03721424IPR009053
DomainEGF_Lam

STAB2 LAMA1 CELSR2

2.36e-03351423SM00180
DomainALDOKETO_REDUCTASE_1

AKR1C1 AKR1C2

2.48e-03101422PS00798
DomainALDOKETO_REDUCTASE_2

AKR1C1 AKR1C2

2.48e-03101422PS00062
DomainHAT

ZFC3H1 PDCD11

2.48e-03101422SM00386
DomainALDOKETO_REDUCTASE_3

AKR1C1 AKR1C2

2.48e-03101422PS00063
DomainAldo/ket_reductase_CS

AKR1C1 AKR1C2

2.48e-03101422IPR018170
DomainAldo/keto_reductase

AKR1C1 AKR1C2

2.48e-03101422IPR020471
DomainHAT

ZFC3H1 PDCD11

2.48e-03101422IPR003107
DomainRA

RGL3 RASSF5 RIN1

2.56e-03361423PF00788
PathwayREACTOME_KINESINS

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF28P KIF4B KIF3C

1.38e-09571239MM15714
PathwayREACTOME_KINESINS

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C

5.34e-08611238M977
PathwayREACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF28P KIF4B KIF3C

1.79e-07981239MM15352
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF28P KIF4B KIF3C

7.60e-071161239MM15715
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF28P KIF4B KIF3C

2.11e-061311239MM15497
PathwayREACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C

2.54e-061001238M27650
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C

2.23e-051341238M27751
PathwayREACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF28P KIF4B KIF3C

4.09e-051891239MM15356
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C

1.20e-041701238M941
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

CYP27A1 AKR1C1 AKR1C2

1.74e-04131233M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

CYP27A1 AKR1C1 AKR1C2

1.74e-04131233MM14747
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

CYP21A2 AKR1C1 AKR1C2

2.20e-04141233M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

CYP27A1 AKR1C1 AKR1C2

2.20e-04141233M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

CYP21A2 AKR1C1 AKR1C2

2.20e-04141233M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

CYP27A1 AKR1C1 AKR1C2

2.20e-04141233MM14748
PathwayREACTOME_CILIUM_ASSEMBLY

EXOC6 CCT3 FBF1 NPHP4 KIF3A KIF3B KIF3C KIF17

3.77e-042011238M27472
PathwayREACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF4B KIF3C

4.03e-042031238M27654
PathwayREACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION

KIF18A KIF4A KIF3A KIF3B KIF4B KIF3C

5.30e-041161236MM14855
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF21B KIF18A KIF21A KIF4A KIF3A KIF4B KIF3C KIF17

2.77e-1237146811416179
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

URI1 CCT3 RASA3 UBR4 CEP350 PHKG2 MAP1S INTS2 ICAM5 LRRC1 INTS4 PRKDC SNRPA1 PHLPP2 TRDMT1 DOP1B PPP1R16A

3.59e-105731461728330616
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DMXL2 STAG1 CORO2A KIF21A UBR4 DAD1 ZFC3H1 HUWE1 FMNL2 KIF3A CEP350 PTPN13 HEATR6 MAP1S RALBP1 ARID5B LRP2 NR1H2 PRKDC PLEC PREX1 DOP1B

2.26e-0812851462235914814
Pubmed

Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.

KIF3A KIF3B KIF3C

7.25e-083146326445448
Pubmed

Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.

KIF3A KIF3B KIF3C

7.25e-083146327637334
Pubmed

Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation.

KIF3A KIF3B KIF3C

7.25e-083146311331403
Pubmed

Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.

KIF3A KIF3B KIF17

7.25e-083146328761002
Pubmed

Kinesin-2 and photoreceptor cell death: requirement of motor subunits.

KIF3A KIF3B KIF3C

7.25e-083146316337628
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TANC2 STAG1 CCT3 KIF21A KIF4A HUWE1 TUBGCP2 SHOC2 NUP155 LRRC1 BUB1B PRKDC PLEC SNRPA1

1.85e-075821461420467437
Pubmed

Molecular motors: the driving force behind mammalian left-right development.

KIF3A DNAH1 KIF3B

2.89e-074146310652513
Pubmed

Ciliary targeting of olfactory CNG channels requires the CNGB1b subunit and the kinesin-2 motor protein, KIF17.

KIF3A KIF3B KIF17

2.89e-074146316782012
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RALGAPA1 KIF21B JADE3 KIF21A FBF1 ICE1 SHOC2 CNOT6 NUP155 GTF3C2 SBF1 INTS2 PDCD11

4.06e-075291461314621295
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RALGAPA1 KIF18A URI1 CCT3 HUWE1 SHOC2 CCDC61 CEP350 ESYT2 MTMR4 PTPN13 NUP155 SBF1 LRRC1 INTS4 STYXL1 HELZ PHLPP2

4.66e-0710491461827880917
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 KIF21B DMXL2 CCT3 KIF21A TRPC4 UBR4 ARHGEF12 KIF4A HUWE1 KIF3A KIF3B CELSR2 SBF1 ICAM5 KIF4B UNC13A

6.74e-079631461728671696
Pubmed

Different roles for KIF17 and kinesin II in photoreceptor development and maintenance.

KIF3A KIF3B KIF17

7.20e-075146319384852
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 RASA3 UBR4 ICE1 HUWE1 NPHP4 ABCA7 MYOF CELSR2 MAP1S SBF1 KCTD15 PDCD11 PRKDC PLEC ULK2 PREX1 PPP1R16A

9.81e-0711051461835748872
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

CCT3 ICE1 MYOF HEATR6 SBF1 UTP20 PRKDC PLEC

2.39e-06202146833005030
Pubmed

Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells.

KIF4A HUWE1 KIF4B

2.51e-067146323362347
Pubmed

Kinesin family in murine central nervous system.

KIF4A KIF3A KIF4B

2.51e-06714631447303
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TANC2 EXOC6 KIF18A URI1 MCM7 SHOC2 NPHP4 FMNL2 KIF3A CNOT6 RIN1 PHKG2 PTPN13 KIF3B CNOT6L GTF3C2 HELZ KIF3C PLEC

2.99e-0613211461927173435
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF3A KIF3B KIF3C KIF17

3.52e-062514649275178
Pubmed

Phenotypic annotation of the mouse X chromosome.

JADE3 KIF4A HUWE1 KIF4B RBM41

5.99e-0661146520548051
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

STAG1 CCT3 INSR KIF4A TUBGCP2 SHOC2 CNOT6 CEP350 CNOT6L NUP155 PER3 GTF3C2 MAP1S BUB1B KIF4B PRKDC SNRPA1

7.66e-0611551461720360068
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

CCT3 UBR4 KIF4A MCM7 HUWE1 MYOF ESYT2 NUP155 PRKDC SNRPA1

7.83e-063991461037536630
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TANC2 DMXL2 ZFC3H1 NPHP4 FMNL2 ATP8B2 LAPTM5 CEP350 MYOF PER3 PREX1

8.16e-064931461115368895
Pubmed

The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3.

KIF3A KIF3B KIF17

1.17e-051114639427749
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

UBR4 MCM7 ICE1 HUWE1 PTPN13 GTF3C2 BUB1B ARID5B LRP2 PLEC

1.17e-054181461034709266
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

CCT3 UBR4 HUWE1 KLHL22 CEP350 MYOF PLEC

1.26e-05182146731067453
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CCT3 KIF21A UBR4 LAMA1 ICE1 HUWE1 FMNL2 ARID5B LRP2 UTP20 PRKDC RBM41 DOP1B

1.48e-057361461329676528
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

1.75e-052146236482480
Pubmed

Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

AKR1C1 AKR1C2

1.75e-05214628573067
Pubmed

Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B.

KIF21B KIF21A

1.75e-052146210225949
Pubmed

Increased hippocampal neurogenesis and accelerated response to antidepressants in mice with specific deletion of CREB in the hippocampus: role of cAMP response-element modulator Ï„.

CREB1 CREM

1.75e-052146223966689
Pubmed

Fast or Slow, Either Head Can Start the Processive Run of Kinesin-2 KIF3AC.

KIF3A KIF3C

1.75e-052146226710851
Pubmed

Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling.

AKR1C1 AKR1C2

1.75e-052146215492289
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

1.75e-052146230081192
Pubmed

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

KIF4A KIF4B

1.75e-052146231067151
Pubmed

CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.

CNOT6 CNOT6L

1.75e-052146234788619
Pubmed

Cyclic adenosine 5'-monophosphate response element binding protein plays a central role in mediating proliferation and differentiation downstream of the pre-TCR complex in developing thymocytes.

CREB1 CREM

1.75e-052146215265911
Pubmed

Photoreceptor localization of the KIF3A and KIF3B subunits of the heterotrimeric microtubule motor kinesin II in vertebrate retina.

KIF3A KIF3B

1.75e-052146210548469
Pubmed

Cyclic AMP response element-binding protein is required for normal maternal nurturing behavior.

CREB1 CREM

1.75e-052146215893884
Pubmed

Cellular motor protein KIF-4 associates with retroviral Gag.

KIF4A KIF4B

1.75e-052146210559369
Pubmed

CTG repeat instability and size variation timing in DNA repair-deficient mice.

PRKDC RAD54L

1.75e-052146212727892
Pubmed

Kinesin-2 KIF3AB exhibits novel ATPase characteristics.

KIF3A KIF3B

1.75e-052146225122755
Pubmed

KIF4 regulates midzone length during cytokinesis.

KIF4A KIF4B

1.75e-052146221565503
Pubmed

The effect of laminin-1 on enteric neural crest-derived cell migration in the Hirschsprung's disease mouse model.

LAMA1 EDNRB

1.75e-052146229018955
Pubmed

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

KIF4A KIF4B

1.75e-05214627929562
Pubmed

Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.

AKR1C1 AKR1C2

1.75e-052146221217827
Pubmed

Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.

TRPC4 TRPC5

1.75e-052146222457348
Pubmed

The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds.

KIF3A KIF3B

1.75e-052146215345558
Pubmed

Characterization of the KIF3C neural kinesin-like motor from mouse.

KIF3A KIF3C

1.75e-05214629450952
Pubmed

Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity.

CREB1 CREM

1.75e-052146221998402
Pubmed

Conserved gating elements in TRPC4 and TRPC5 channels.

TRPC4 TRPC5

1.75e-052146223677990
Pubmed

Role of mammalian Rad54 in telomere length maintenance.

PRKDC RAD54L

1.75e-052146212897131
Pubmed

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.

TRPC4 TRPC5

1.75e-052146232033274
Pubmed

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

TRPC4 TRPC5

1.75e-052146217624425
Pubmed

cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.

AKR1C1 AKR1C2

1.75e-05214628486699
Pubmed

An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription.

CREB1 CREM

1.75e-05214627809053
Pubmed

KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport.

KIF3A KIF3B

1.75e-05214627559760
Pubmed

Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript.

CREB1 CREM

1.75e-05214627916662
Pubmed

Cyclic AMP response element binding protein CREB and modulator protein CREM are products of distinct genes.

CREB1 CREM

1.75e-05214621461747
Pubmed

The expanding family of CREB/CREM transcription factors that are involved with spermatogenesis.

CREB1 CREM

1.75e-052146211988318
Pubmed

The mechanochemistry of the kinesin-2 KIF3AC heterodimer is related to strain-dependent kinetic properties of KIF3A and KIF3C.

KIF3A KIF3C

1.75e-052146232571914
Pubmed

Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.

TRPC4 TRPC5

1.75e-052146234899056
Pubmed

Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.

TRPC4 TRPC5

1.75e-052146217593972
Pubmed

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

AKR1C1 AKR1C2

1.75e-052146211514561
Pubmed

Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.

KIF4A KIF4B

1.75e-052146231486502
Pubmed

Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.

KIF4A KIF4B

1.75e-052146210773663
Pubmed

The role of cAMP response element-binding protein in estrogen negative feedback control of gonadotropin-releasing hormone neurons.

CREB1 CREM

1.75e-052146222895714
Pubmed

cAMP response element-binding protein regulates differentiation and survival of newborn neurons in the olfactory bulb.

CREB1 CREM

1.75e-052146216267218
Pubmed

The myotubularin phosphatase MTMR4 regulates sorting from early endosomes.

EXOC6 MTMR4

1.75e-052146220736309
Pubmed

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

KIF4A KIF4B

1.75e-052146231616463
Pubmed

Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.

KIF4A KIF4B

1.75e-052146228350061
Pubmed

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.

TRPC4 TRPC5

1.75e-052146226317356
Pubmed

Transcription factor CREB is involved in CaSR-mediated cytoskeleton gene expression.

CASR CREB1

1.75e-052146225382680
Pubmed

A novel capacitative calcium entry channel expressed in excitable cells.

TRPC4 TRPC5

1.75e-05214629687496
Pubmed

Torque generation of kinesin motors is governed by the stability of the neck domain.

KIF3A KIF3B

1.75e-052146222541555
Pubmed

Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.

KIF4A KIF4B

1.75e-052146224658398
Pubmed

Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform.

CREB1 CREM

1.75e-05214628605879
Pubmed

cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase.

AKR1C1 AKR1C2

1.75e-05214628011662
Pubmed

The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.

CNOT6 CNOT6L

1.75e-052146221233283
Pubmed

Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors.

AKR1C1 AKR1C2

1.75e-052146218654764
Pubmed

Structural basis for the ATP-induced isomerization of kinesin.

KIF4A KIF4B

1.75e-052146223500491
Pubmed

Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells.

CREB1 CREM

1.75e-052146220920259
Pubmed

Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test.

CREB1 CREM

1.75e-052146229044198
Pubmed

Altered expression of laminin alpha1 in aganglionic colon of endothelin receptor-B null mouse model of Hirschsprung's disease.

LAMA1 EDNRB

1.75e-052146228983681
Pubmed

The roles of AKR1C1 and AKR1C2 in ethyl-3,4-dihydroxybenzoate induced esophageal squamous cell carcinoma cell death.

AKR1C1 AKR1C2

1.75e-052146226934124
Pubmed

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.

KIF4A KIF4B

1.75e-05214629658142
Pubmed

Identification of human myometrial target genes of the cAMP pathway: the role of cAMP-response element binding (CREB) and modulator (CREMalpha and CREMtau2alpha) proteins.

CREB1 CREM

1.75e-052146215691874
Pubmed

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.

TRPC4 TRPC5

1.75e-052146230038709
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

CCT3 FBF1 UBR4 MCM7 HUWE1 TUBGCP2 CEP350 PHKG2 SBF1 BUB1B HELZ PRKDC

1.76e-056391461223443559
Pubmed

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.

KIF18A URI1 CCT3 MCM7 SHOC2 RASSF5 PTPN13 MAP1S

1.99e-05270146824366813
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

CYP27A1 AKR1C1 AKR1C2

2.01e-0513146311682476
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

CYP21A2 AKR1C1 AKR1C2

2.01e-0513146324580729
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TANC2 RALGAPA1 FBF1 TBC1D22B TUBGCP2 RASSF5 PTPN13 MAP1S HELZ PRKDC

2.04e-054461461024255178
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

CCT3 ESRRB LAMA1 KIF4A SHOC2 HELZ KIF4B

2.54e-05203146722083510
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

KIF18A KIF4A CEP350 UTP20 PRKDC PLEC ALK

3.16e-05210146716565220
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

CCT3 MCM7 HUWE1 TUBGCP2 SHOC2 GTF3C2 PRKDC

3.26e-05211146717314511
Pubmed

Defining the membrane proteome of NK cells.

UBR4 DAD1 KIF4A B3GALT6 MCM7 HUWE1 TUBGCP2 CNOT6 CEP350 ESYT2 MGAT2 KIF3B NUP155 INTS2 HELZ PRKDC

3.44e-0511681461619946888
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

CCT3 UBR4 MCM7 HUWE1 ESYT2 PDCD11 PRKDC

4.37e-05221146729991511
Cytoband10p15-p14

AKR1C1 AKR1C2

1.49e-046146210p15-p14
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF21B KIF18A KIF21A KIF4A KIF3A KIF3B KIF28P KIF4B KIF3C KIF17

7.92e-144610310622
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KIF18A URI1 TRPC5 MCM7 TMEM132D SPOCD1 PPP1R16A

7.92e-051811037694
GeneFamilyUNC13 homologs

UNC13C UNC13A

1.91e-0441032836
GeneFamilyCCR4-NOT transcription complex

CNOT6 CNOT6L

1.71e-031110321023
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR4 SBF1

3.22e-03151032903
GeneFamilyIntegrator complex

INTS2 INTS4

3.22e-031510321366
GeneFamilyAldo-keto reductases

AKR1C1 AKR1C2

3.22e-03151032399
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DMXL2 URI1 STAG1 SHOC2 CREB1 CEP350 MYOF PTPN13 GTF3C2 LRIG1 BUB1B ARID5B HELZ UTP20 ADGRA3 PHLPP2 DOP1B

6.03e-0685614617M4500
CoexpressionGSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP

TRPC5 AKR1C2 KLHL22 MAP1S NR1H2 KIF3C SNRPA1 ULK2

1.65e-051991468M7379
CoexpressionHALLMARK_MITOTIC_SPINDLE

ARHGEF12 KIF4A TUBGCP2 KIF3B MAP1S RALBP1 KIF3C PREX1

1.65e-051991468M5893
CoexpressionCAIRO_HEPATOBLASTOMA_CLASSES_UP

KIF18A CCT3 KIF4A MCM7 HUWE1 CNOT6 GTF3C2 LRRC1 BUB1B PDCD11 UTP20 PRKDC DOP1B

4.02e-0561214613M4772
CoexpressionGSE21033_3H_VS_24H_POLYIC_STIM_DC_UP

INSR RAD9B FMNL2 LRIG1 LRRC1 HELZ PREX1

4.17e-051661467M7722
CoexpressionENGELMANN_CANCER_PROGENITORS_DN

CORO2A SLC35C1 AKR1C1 AKR1C2 VPS37D

4.22e-05691465M9246
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB CASR KCTD1 BARX2 MYOF UNC13C PHF21B

1.98e-071871468f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 CNOT6L UNC13C PHF21B

2.06e-071881468eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RGL3 ESRRB KCTD1 BARX2 MYOF UNC13C PHF21B

2.15e-071891468e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

TRHDE TANC2 CORO2A CYP27A1 FMNL2 AKR1C1 AKR1C2 SPOCD1

2.33e-071911468a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

TANC2 KIF21B KIF21A INSR MTMR4 CELSR2 KIF3C UNC13A

3.30e-072001468c92e4fc0442404481fcac623d691dae6215b852d
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

TRHDE TANC2 CYP27A1 FMNL2 AKR1C1 AKR1C2 SPOCD1

2.66e-06185146785cb81759589a26d83676cffbf2bc37399683c10
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

STAG1 JADE3 ARHGEF12 CREB1 CNOT6 CEP350 RBM41

2.75e-06186146703db813598b67b1e08f759758a1c2023396921fa
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B ADGRA3

2.85e-061871467dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B ADGRA3

2.85e-0618714674d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B ADGRA3

2.85e-061871467ae90c263f80c36a410150d499e268d198944a3d9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 RGL3 ESRRB CASR MYOF ESYT2 PHF21B

2.85e-06187146777886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 CNOT6L PHF21B

2.96e-061881467bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRHDE ESRRB LAMA1 CASR KCTD1 PHF21B CDH16

2.96e-0618814671d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB LAMA1 CASR KCTD1 CNOT6L UNC13C PHF21B

3.06e-061891467977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B CDH16

3.06e-06189146755420853f730b433ef58ac9337ac84ac78a247a0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ESRRB LAMA1 CASR KCTD1 MYOF ARID5B

3.17e-061901467bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ESRRB LAMA1 CASR KCTD1 MYOF ARID5B

3.17e-061901467b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ESRRB LAMA1 CASR KCTD1 MYOF ARID5B

3.28e-0619114672fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ESRRB LAMA1 CASR KCTD1 MYOF ARID5B

3.28e-0619114679032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B CDH16

3.28e-0619114670965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ESRRB LAMA1 CASR KCTD1 MYOF ARID5B

3.28e-0619114675717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

RALGAPA1 KIF21A HUWE1 CREB1 CNOT6 CEP350 PRKDC

3.51e-061931467abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RGL3 ESRRB CASR KCTD1 PTPN13 ADGRA3

3.76e-0619514676477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TBX3 VASN ARHGEF12 EDNRB P2RY1 PLEC PREX1

4.44e-0620014677034f57e282982c19c13ee8ab78eabaffa069e30
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

B3GALT6 KLHL22 PRDM1 LRIG1 GALNT8 ARID5B

1.43e-05159146608a1cd71eac4322fb313324f74fe8e37998f2d7d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

B3GALT6 KLHL22 PRDM1 LRIG1 GALNT8 ARID5B

1.43e-0515914669bdfa7f5aa7753fe25b787bd43d694b6093d77eb
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZFC3H1 CHKA AKR1C1 CNOT6 PDCD11 KIF3C

1.53e-05161146658381131e651744b5141b202f9d6063f55432db5
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HTR7 CORO2A TLR9 FMNL2 LAPTM5 MTMR4

1.70e-051641466662f74ad2656c0af158dbf9eb81d5bf70f54e529
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHP4 RIN1 ICAM5 CHSY3 KIF17 NPAS4

1.76e-0516514661b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHP4 RIN1 ICAM5 CHSY3 KIF17 NPAS4

1.76e-051651466b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC4 NPHP4 RIN1 ICAM5 CHSY3 KIF17

1.95e-051681466b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC4 NPHP4 RIN1 ICAM5 CHSY3 KIF17

1.95e-051681466b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 CORO2A CYP21A2 LAPTM5 MYOF UNC13C

1.95e-051681466a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HTR7 CYP27A1 BARX2 FMNL2 LRRC1 CHSY3

2.30e-05173146670c0c13febd28b395fb3171ec8d7fbbc6c9d4eb7
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPC4 HPSE2 EDNRB PTPN13 CCL11 ALK

2.38e-051741466f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE TRPC4 TRPC5 HPSE2 AKR1C1 AKR1C2

2.54e-05176146603d194c9814e12802cd932afade69e868814cb78
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE TRPC4 TRPC5 HPSE2 AKR1C1 AKR1C2

2.70e-051781466a62137d7f5fac16619f8a02844cdb0be7a794bf2
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 VASN EDNRB PRDM1

2.97e-0554146468c762094ea29e321a6fd4f6d9b598431023fa7b
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 VASN EDNRB PRDM1

2.97e-055414647816e6541e3a9e702f25bd102a95ce963ce31535
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HTR7 TRPC4 TRPC5 HPSE2 PRDM1 ALK

2.97e-051811466bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE TRPC4 TRPC5 HPSE2 AKR1C1 AKR1C2

3.06e-0518214661647367b75b4b107af06bb934394168230cfd7c2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ESRRB CASR MYOF ESYT2 ULK2

3.06e-051821466a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TBX3 RASA3 HPSE2 FMNL2 PHF21B ADGRA3

3.06e-051821466ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRHDE TRPC4 EDNRB CELSR2 BUB1B ALK

3.16e-051831466e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STAB2 LAMA1 DNAH1 LRP2 UNC13C

3.25e-0518414662cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HTR7 IDI2-AS1 TRPC4 TRPC5 PRDM1 ALK

3.25e-0518414662ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STAB2 LAMA1 DNAH1 LRP2 UNC13C

3.25e-051841466ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STAB2 LAMA1 DNAH1 LRP2 UNC13C

3.25e-0518414662b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF12 PTPN13 TMEM132D CHSY3 UNC13C ADGRA3

3.25e-051841466102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

KIF18A KIF4A MCM7 BUB1B KIF4B RAD54L

3.35e-0518514660ae9c646679c69a553eda670aef0e0495feb0286
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RGL3 KIF21A CHKA MYOF PTPN13 FAM13A

3.46e-0518614664e94158db52df41d71e67b02b9895a358eebee0f
ToppCellPBMC-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

LAMA1 CHKA CREM PRDM1 RASSF5 PPP1R16A

3.56e-0518714660afef5baf3752314dbfb024790347d5e51f9b84b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 EDNRB LRIG1 PHF21B ADGRA3

3.56e-0518714662b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B

3.78e-051891466f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EXOC6 STAB2 LAMA1 AKR1C1 AKR1C2 ULK2

3.78e-0518914660739baad9a7da511dd3d7249f84299aee88370a1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B

3.78e-051891466975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellControl-Myeloid-Macrophage_Alveolar|Control / Disease state, Lineage and Cell class

TRHDE TANC2 CYP27A1 FMNL2 AKR1C2 SPOCD1

3.78e-051891466937e876122bc4b94372a4104e9c1a9068c232018
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B

3.78e-0518914667eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

KIF18A KIF21A KIF4A MCM7 KIF4B RAD54L

3.89e-051901466005967c540418b85311308072a07c684f4296aef
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B

3.89e-0519014665c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF18A JADE3 MCM7 LRIG1 BUB1B RAD54L

3.89e-0519014667be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B

3.89e-051901466b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellIPF-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

TRHDE TANC2 CYP27A1 FMNL2 AKR1C2 SPOCD1

3.89e-0519014662592765016f291565697265800a232b2edef3792
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B

3.89e-0519014663dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB LAMA1 CASR KCTD1 UNC13C PHF21B

3.89e-051901466e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VASN CREM EDNRB ESYT2 RALBP1 CDH16

4.01e-05191146665083daf317f66556dc047eb19297dcbe9c70299
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like|3_mon / Sample Type, Dataset, Time_group, and Cell type.

EFS SSR2 ARID5B KCTD15 TAC3 PREX1

4.01e-05191146648cffb55c71bb8b34e926fc461fcd345ce43ea00
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

EFS SSR2 ARID5B KCTD15 TAC3 PREX1

4.01e-051911466e4c1c533771b582e21683dbec6f93a558d865e00
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRHDE ESRRB LAMA1 CASR KCTD1 PHF21B

4.01e-051911466fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CORO2A RGL3 LAMA1 KIF4A BUB1B LRP2

4.13e-05192146625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B

4.13e-051921466f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 HPSE2 AKR1C1 EDNRB RALBP1 UNC13C

4.13e-0519214666c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B

4.13e-05192146643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGL3 ESRRB LAMA1 CASR KCTD1 PHF21B

4.13e-051921466562df5e87038c500dd3a003fe5374cb31946b145
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B

4.13e-051921466705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B

4.25e-051931466b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGL3 LAMA1 HPSE2 EDNRB LRIG1 PHF21B

4.25e-05193146640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RGL3 ESRRB CASR PTPN13 LRP2

4.25e-05193146682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VASN BARX2 EDNRB PTPN13 RALBP1 CDH16

4.25e-051931466d994b2f2707877288f88cab7cd6002ef91962c50
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE TANC2 CASR KCTD1 MYOF ADGRA3

4.37e-051941466e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RGL3 ESRRB LAMA1 KCTD1 PTPN13

4.37e-05194146693c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RGL3 CASR KCTD1 PTPN13 CDH16

4.37e-0519414665eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

KIF18A KIF4A MCM7 BUB1B KIF4B RAD54L

4.37e-051941466a12b64945e10f00aa983678a02586c59badc1570
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HTR7 RASA3 PRDM1 CNOT6L FAM13A ARID5B

4.37e-051941466a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCellCOVID-19_Mild-PLT_5|COVID-19_Mild / Disease Group and Platelet Clusters

CCT3 INSR HUWE1 TUBGCP2 LAPTM5 RASSF5

4.50e-051951466bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF18A KIF4A MCM7 BUB1B KIF4B RAD54L

4.63e-0519614669591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE RGL3 ESRRB LAMA1 KCTD1 PTPN13

4.63e-051961466eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ICE1 PRDM1 PTPN13 CNOT6L ARID5B PRKDC

4.63e-0519614664a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TANC2 KIF21A CHKA KIF3A PTPN13 FAM13A

4.90e-051981466aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCell(5)_Dendritic_cell-(52)_cycling_DCs|(5)_Dendritic_cell / shred on Cell_type and subtype

KIF18A DMXL2 KIF4A MCM7 PRDM1 BUB1B

5.03e-051991466d0ff446a197062b10f37b585f3f8716d6d89e5b7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VASN BARX2 EDNRB PTPN13 RALBP1 CDH16

5.03e-051991466a4ebb0598e9a0c9f6e39a0db6d0623654c2a7d88
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

HTR7 TRPC4 TRPC5 PRDM1 ALK PHF21B

5.18e-0520014664a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

KIF18A KIF4A MCM7 BUB1B KIF4B RAD54L

5.18e-052001466e4eb915c29909cf8535a3603c68976545c05e54b
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

DMXL2 KIF4A MCM7 FMNL2 BUB1B SNRPA1

5.18e-052001466372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

KIF18A KIF4A MCM7 BUB1B KIF4B RAD54L

5.18e-052001466415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

HTR7 TRPC4 TRPC5 PRDM1 ALK PHF21B

5.18e-052001466fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

HTR7 TRPC4 TRPC5 PRDM1 ALK PHF21B

5.18e-052001466c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

UBR4 IRAK2 CREM LAPTM5 RASSF5 PLEC

5.18e-05200146674ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAT3 VASN RGL3 BUB1B MVK

1.28e-0414814656cd7ef4f29d9a0944f724d9d8117d4d25e517fe4
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

HPSE2 TMEM132D UNC13C ALK UNC13A

1.36e-0415014650205318a870e091add66ee4305747dda9f51510d
Drugethacrynic acid

KIF18A KIF21A KIF4A AKR1C1 KIF3A KIF3B KIF3C KIF17

3.10e-061381468CID000003278
DrugRescinnamin [24815-24-5]; Up 200; 6.4uM; HL60; HT_HG-U133A

TANC2 HTR7 JADE3 UBR4 CREM PRDM1 MYOF FAM13A LRRC1

3.30e-0618614692130_UP
DrugSyrosingopine [84-36-6]; Up 200; 6uM; HL60; HG-U133A

PIGL CEL CYP27A1 CREM PHKG2 PDCD11 TAC3 KIF3C PLEC

4.10e-0619114691761_UP
DrugThioguanosine [85-31-4]; Down 200; 12.6uM; PC3; HT_HG-U133A

SLC35C1 CREB1 CEP350 MGAT2 PER3 LRRC1 BUB1B MVK DOP1B

4.85e-0619514696643_DN
DrugBiperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A

DMXL2 CEL TRPC4 TRPC5 ATP8B2 PRDM1 RIN1 MYOF PHLPP2

4.85e-0619514693321_UP
DrugDipyridamole [58-32-2]; Down 200; 8uM; PC3; HG-U133A

TRHDE TBX3 DMXL2 ARHGEF12 CHKA SHOC2 CREB1 CREM RALBP1

4.85e-0619514691934_DN
DrugHexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; MCF7; HT_HG-U133A

SLC35C1 TUBGCP2 ATP8B2 CREM KLHL22 CEP350 PTPN13 MAP1S SBF1

5.49e-0619814691482_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

STAG1 TRPC4 CASR ATP8B2 HEATR6 KCTD15 KIF3C ULK2 MVK

5.72e-0619914692993_DN
DrugYF-1

NLRP11 CEL CYP27A1 INSR TLR9 RALBP1

1.58e-05831466CID000445779
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; HL60; HT_HG-U133A

TRHDE KIF21B PIGL URI1 MGAT2 PDCD11 UTP20 KIF17

3.33e-0519114686149_DN
DrugSC-560; Up 200; 10uM; MCF7; HT_HG-U133A

STAG1 NPHP4 CREM KLHL22 PTPN13 PER3 LRRC1 DLX4

3.86e-0519514686913_UP
DrugLactobionic acid [96-82-2]; Down 200; 11.2uM; PC3; HT_HG-U133A

RALGAPA1 INSR TUBGCP2 ABCA7 ATP8B2 CEP350 MGAT2 SBF1

4.00e-0519614686605_DN
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

4.08e-0521462DB07768
Drug9-ethyl-6,6-dimethyl-8-(4-oxetan-3-ylpiperazin-1-yl)-11-oxo-6,11-dihydro-5H-benzo(b)carbazole-3-carbonitrile

INSR ALK

4.08e-0521462ctd:C562235
DrugSulfamerazine [127-79-7]; Up 200; 15.2uM; HL60; HT_HG-U133A

RASA3 SLC35C1 UBR4 PDCD11 PLEC KIF17 ULK2 DOP1B

4.14e-0519714682181_UP
DrugLobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; HL60; HG-U133A

TRHDE DMXL2 TUBGCP2 NPHP4 PHKG2 MYOF KCTD15 KIF3C

4.14e-0519714681747_DN
DrugSulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A

CREB1 ATP8B2 CREM PTPN13 SBF1 KIF3C RBM41 MVK

4.14e-0519714683484_DN
DrugMeropenem [96036-03-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A

SLC35C1 ARHGEF12 LRRC1 PDCD11 KIF3C PLEC ULK2 MVK

4.30e-0519814687180_DN
DrugIsradipine [75695-93-1]; Up 200; 10.8uM; PC3; HT_HG-U133A

STAB2 TRPC5 ABCA7 MGAT2 PER3 LRP2 ULK2 MVK

4.30e-0519814686347_UP
DrugTheobromine [83-67-0]; Down 200; 22.2uM; HL60; HT_HG-U133A

RASA3 TRPC4 TRPC5 CASR KLHL22 MYOF FAM13A PLEC

4.30e-0519814682995_DN
DrugCP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A

KIF21B TBX3 EFS INSR TBC1D22B RIN1 GALNT8 CCL11

4.30e-0519814684383_UP
DrugNomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A

CREB1 ATP8B2 CEP350 MYOF HEATR6 SBF1 KIF3C MVK

4.30e-0519814682062_DN
DrugMethacholine chloride [62-51-1]; Down 200; 20.4uM; PC3; HT_HG-U133A

SLC35C1 CYP27A1 ARHGEF12 CREM KLHL22 MYOF DLX4 ULK2

4.45e-0519914685773_DN
DrugCondelphine [7633-69-4]; Up 200; 8.8uM; PC3; HT_HG-U133A

STAB2 ARHGEF12 TUBGCP2 MGAT2 FAM13A CELSR2 ALK PHLPP2

4.45e-0519914686357_UP
DrugPropranolol hydrochloride [318-98-9]; Down 200; 13.6uM; HL60; HT_HG-U133A

TANC2 DMXL2 STAB2 ARHGEF12 EDNRB DLX4 KIF3C UNC13A

4.45e-0519914683059_DN
Drug2-aminoethoxydiphenyl borate

TRPC4 TRPC5 CASR CREB1 EDNRB

4.51e-05611465ctd:C109986
DrugAC1L1IHP

KIF18A CEL KIF21A INSR KIF4A CHKA CREB1 CREM KIF3A PHKG2 PTPN13 KIF3B KIF3C PRKDC KIF17

7.10e-0572814615CID000004584
Diseasemyeloid white cell count

PIGL CEL RASA3 CYP21A2 ARHGEF12 SSR2 FMNL2 ABCA7 LAPTM5 RASSF5 FAM13A STYXL1 KIF3C PREX1 VPS37D

5.26e-0593714315EFO_0007988
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2

6.97e-0531432C0027661
Diseaseperiostin measurement

STAB2 TRPC4

1.39e-0441432EFO_0020628
Diseaseepilepsy (implicated_via_orthology)

KIF4A CHKA SBF1 KIF4B UNC13C UNC13A

1.48e-041631436DOID:1826 (implicated_via_orthology)
DiseaseLiver carcinoma

KIF18A STAB2 VASN KIF4A AKR1C2 LRRC1 BUB1B NR1H2 MVK RAD54L

1.91e-0450714310C2239176
DiseaseHermaphroditism

AKR1C1 AKR1C2

2.31e-0451432C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2

2.31e-0451432C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2

2.31e-0451432C0033804
DiseaseIntersex Conditions

AKR1C1 AKR1C2

2.31e-0451432C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2

2.31e-0451432C2930619
DiseaseDisorders of Sex Development

AKR1C1 AKR1C2

4.82e-0471432C0036875
Diseaseamino acid measurement

TANC2 STAG1 CYP21A2 SHOC2 PER3 LRIG1 LRP2 UNC13C KIF3C PRKDC ALK

4.85e-0467814311EFO_0005134
Diseaseneutrophil percentage of leukocytes

EXOC6 PIGL CEL SHOC2 ABCA7 ICAM5 ARID5B HELZ PRKDC PREX1

8.11e-0461014310EFO_0007990
Diseasefibrinogen measurement, coronary artery disease

CEL STAG1 CYP21A2 CELSR2 MAP1S

9.45e-041541435EFO_0001645, EFO_0004623
Diseasetransverse temporal cortex volume measurement

P2RY1 UNC13C

1.02e-03101432EFO_0010336
Diseasenicotine dependence (implicated_via_orthology)

TRPC4 TRPC5

1.49e-03121432DOID:0050742 (implicated_via_orthology)
Diseaselymphocyte percentage of leukocytes

EXOC6 PIGL CEL RASA3 ABCA7 ICAM5 ARID5B HELZ PRKDC PREX1

1.55e-0366514310EFO_0007993
Diseasefructose measurement

UBR4 P2RY1

1.76e-03131432EFO_0010477
DiseaseMetabolic Bone Disorder

CYP27A1 LRP2

2.04e-03141432C0005944
Diseasehuman papilloma virus infection, oropharynx cancer

CYP21A2 FMNL2 UNC13C

2.19e-03531433EFO_0001668, EFO_1001931
Diseasefactor VIII measurement, coronary artery disease

STAB2 STAG1 CELSR2 MAP1S

2.26e-031131434EFO_0001645, EFO_0004630
DiseaseProteinuria

LRP2 UNC13C

2.35e-03151432HP_0000093
DiseaseOsteopenia

CYP27A1 LRP2

2.35e-03151432C0029453
DiseaseRhabdomyosarcoma

BUB1B ALK

2.35e-03151432C0035412
Diseasefactor XI measurement, coronary artery disease

STAG1 CELSR2 MAP1S MVK

2.41e-031151434EFO_0001645, EFO_0004694
DiseaseIschemic stroke, fibrinogen measurement

STAG1 CYP21A2 PLEC

2.43e-03551433EFO_0004623, HP_0002140
Diseaseantisaccade response measurement

GALNT8 UNC13C PLEC

2.56e-03561433EFO_0006874
Diseasevon Willebrand factor measurement, coronary artery disease

STAB2 STAG1 CELSR2 MAP1S

2.65e-031181434EFO_0001645, EFO_0004629
Diseasepreeclampsia, hypertension, pregnancy-induced

RGL3 PREX1

2.68e-03161432EFO_0000668, MONDO_0024664
Diseaseresponse to methotrexate

AKR1C1 AKR1C2

2.68e-03161432GO_0031427
DiseaseIGF-1 measurement

TBX3 STAB2 STAG1 CYP27A1 ICAM5 ULK2 VPS37D DOP1B

2.69e-034881438EFO_0004627
Diseasefibrinogen measurement, factor VII measurement

STAG1 CYP21A2 PLEC

2.83e-03581433EFO_0004619, EFO_0004623
Diseasemosquito bite reaction size measurement

KIF3A TMEM132D CHSY3 UNC13C PLEC

3.81e-032121435EFO_0008378
Diseasemean platelet volume

CYP21A2 CASR RASSF5 ESYT2 FAM13A KIF28P INTS4 STYXL1 PLEC ULK2 VPS37D MVK

4.12e-03102014312EFO_0004584
Diseasehaptoglobin measurement

CHST4 PHLPP2

4.61e-03211432EFO_0004640
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

EXOC6 RASA3 INSR DNAH1 CELSR2

4.80e-032241435EFO_0004530, EFO_0008317

Protein segments in the cluster

PeptideGeneStartEntry
EKSPDLQSLRYALSL

UNC13A

1486

Q9UPW8
AASRALYPLDKLLDR

TRHDE

756

Q9UKU6
YRRQLLKSLPELSAS

BUB1B

726

O60566
YAAPVLDKRQTSRLL

ADAT3

46

Q96EY9
ALLILYLDSARNLPS

ESYT2

536

A0FGR8
LLPALRDAYENLTAK

B3GALT6

121

Q96L58
SLAPRSAQLNSKRYL

CCDC61

106

Q9Y6R9
LRPTDDSLYKLQLIA

ADGRA3

626

Q8IWK6
PIVKATNRELSYLLL

CASR

641

P41180
LSRILKLTLYNQNDP

EDNRB

341

P24530
SDALLSKDRYLIPNI

DMXL2

1151

Q8TDJ6
LVSLALPLDYKLERQ

CELSR2

666

Q9HCU4
SLQTLSPYNKGLIRR

CEL

221

P19835
KLRKPRTIYSSLQLQ

DLX4

116

Q92988
NLSDFLVKTYPRLVR

ABCA7

1386

Q8IZY2
QRRLDTSSLKLSEYP

ARHGEF12

991

Q9NZN5
LRLNLKPDLSDTVRY

ATP8B2

1106

P98198
NTVASLLKQYLRDLP

RALBP1

261

Q15311
LYLKNLSPRVTERDL

RBM41

311

Q96IZ5
LRIPLKVLRQSSSYE

RASA3

246

Q14644
LFQKLSIADRPLYLR

RASSF5

331

Q8WWW0
LTPLQTELYKRFLRQ

RAD54L

416

Q92698
VRLLLAYNSSARIPK

INTS4

911

Q96HW7
RRLYPKETLTNISAL

RAD9B

321

Q6WBX8
VRALIYKDLDNSPLR

P2RY1

241

P47900
RFLEEYLSSTPQRLK

DAD1

11

P61803
LPSLKTLRVLNLEYN

LRRD1

276

A4D1F6
LNPSDKSLYDELRNL

MAP1S

91

Q66K74
RSLNLSYNKLSEIDP

LRIG1

71

Q96JA1
NRPEYLRLLLDSLRK

MGAT2

126

Q10469
DNNRSPVYLKDLLLS

IRAK2

416

O43187
LYLDKNNLRSLCPAL

LRRIQ4

76

A6NIV6
LLKALARNRSLTYLS

NLRP11

681

P59045
PYRNSKLTRLLKDSL

KIF18A

306

Q8NI77
KALQSNLRYSLLPRR

DOP1B

46

Q9Y3R5
YKDRARLPLLNATIA

CYP21A2

336

P08686
PYRDSKLTRLLQDSL

KIF3C

316

O14782
RNKPSTLDALNYALR

PER3

71

P56645
KNRSAELRVLYAPRL

ICAM5

396

Q9UMF0
YILNFLRTSKLLIPD

KCTD1

86

Q719H9
PYRDSKLTRLLQDSL

KIF21B

321

O75037
LALYKSLARSIPESL

GLYATL1

11

Q969I3
IQYALPKSLSVARLA

INTS2

1066

Q9H0H0
LVSNAPYDRLKLSLL

HEATR6

546

Q6AI08
RNLDPLVYLLSKLTE

TUBGCP2

76

Q9BSJ2
LLLPDNVRIRKYNLS

LRP2

4056

P98164
LKSYLRSLRPEAENN

INSR

1111

P06213
LKSLLQPIRIYSRAS

HPSE2

286

Q8WWQ2
PYRNSKLTRLLQDSL

KIF3A

296

Q9Y496
ILSALQSNPIYRLKR

RGL3

346

Q3MIN7
PQLSLRLSYRKACLE

FAM13A

306

O94988
KSLLIRYQIPLSADQ

HELZ

426

P42694
NYITRLGSDKRTPLL

HUWE1

146

Q7Z6Z7
LTKNALLRDPYALRS

PHKG2

331

P15735
KYLRVNPNTALTLLE

EXOC6

746

Q8TAG9
NLLTYLPDSLTQLRR

LRRC1

161

Q9BTT6
AKSQLLSYIDRLAPR

MCM7

386

P33993
AAPQKLLILDARSYT

MTMR4

301

Q9NYA4
DSPISASQDKRLRLY

NPHP4

141

O75161
LPRLLEVYDQLFKSR

NUP155

1296

O75694
SYLLLPLDSSKSRLL

SBF1

766

O95248
VLLNLSFTYLKLDRP

FKBP6

221

O75344
LLPLAEADKVRLSYL

NPAS4

26

Q8IUM7
VFLNKYLLDSPSLRL

SLC35C1

56

Q96A29
RIFSLPITNYDKLSR

DNAH1

1001

Q9P2D7
LARSLLPSTEYQKQL

FBF1

551

Q8TES7
YPELSARARTLNILK

ICE1

1756

Q9Y2F5
LPLEKVYSLLSSNRL

KLHL22

191

Q53GT1
KLLSYNLPLELENLR

CHKA

276

P35790
PYALDLTAALKRNAL

GALNT8

416

Q9NY28
KYLSTPDRLDLAQSL

BARX2

156

Q9UMQ3
LNQRLLKPAEAALYT

CYP27A1

161

Q02318
SIPKQLLTRNLTAYR

CORO2A

111

Q92828
LSPLSRNIKARLLLY

IDI2-AS1

81

Q9NZ38
PSATRRLQETYSKLL

CEP350

651

Q5VT06
IYAAPSNLKRASALL

EFS

216

O43281
RRPSYRKILNDLSSD

CREB1

116

P16220
SALRYNTLPSRRTLK

FMNL2

196

Q96PY5
VPYRDSKLTRLLQDS

KIF4A

286

O95239
VPYRDSKLTRLLQDS

KIF4B

286

Q2VIQ3
KRRLDSESSPYLSLQ

ESRRB

186

O95718
SRRPSYRKILNELSS

CREM

116

Q03060
LVYLDLSSNKIRSLP

CNOT6

76

Q9ULM6
YPLESKNNRLLASLS

JADE3

596

Q92613
PYRDSVLTKLLQSAL

KIF28P

306

B7ZC32
RLRLCKNLSYEAAPS

CDH16

511

O75309
SSLSSNPYVKRLDLR

LRRC74B

101

Q6ZQY2
LRQSRLSLYPGDTIK

PTPN13

496

Q12923
ILKRLSCSELSLYQP

PTPN13

931

Q12923
LTPLLNLLIYSLRNS

OR10A6

281

Q8NH74
PYRDSKLTRLLQDSL

KIF17

286

Q9P2E2
RVQADRDYSPLLKRL

RUNDC1

371

Q96C34
LSRIAKLEAAYSPRN

UTP20

2626

O75691
RQKLLQLLRTYSPSA

RIN1

496

Q13671
QLLRTYSPSAQVKRL

RIN1

501

Q13671
IPNSRLRYFLIAKLQ

TRDMT1

156

O14717
LRERLSTLPDKLSYN

URI1

61

O94763
YLPANTERRKLTLQR

TBC1D22B

226

Q9NU19
RANDILKLPYSTFRT

TBX3

256

O15119
SFLIYKSRRLPVLNA

TMEM132D

81

Q14C87
SLKSLTYLSILRNPV

SNRPA1

111

P09661
ELPAYLKLASRSRAS

LAPTM5

116

Q13571
NVLRKYISLLDLPLS

PIGL

186

Q9Y2B2
LSPKLLEFTSARYIR

LAMA1

211

P25391
ALLSYTRIKRPQDQL

NR1H2

401

P55055
RLLLLPRSYKAKAAA

SKIDA1

291

Q1XH10
RKLRAFYLERSNLPT

PREX1

1506

Q8TCU6
KRLDRSVSYQLSPLD

PPP1R16A

426

Q96I34
LRYNRLSAIPRSLAK

SHOC2

291

Q9UQ13
ALASLRNLYTPNIKV

TANC2

851

Q9HCD6
RYIKNPRIVLLDSSL

CCT3

231

P49368
LYRSNISPLTSEKDL

PRDM1

266

O75626
KLRQPSNYLIVSLAL

HTR7

111

P34969
REPLSYSRLQRKSLA

ALK

41

Q9UM73
RPALERSLKNLQLDY

AKR1C1

96

Q04828
RPALERSLKNLQLDY

AKR1C2

96

P52895
SRQLLSSSKLYFLPE

ARID5B

66

Q14865
LANRKIPLQRLESYR

CCL11

36

P51671
LEEFLRSLNSSKPLY

CHSY3

271

Q70JA7
QSLPKALQERYLLVR

CHST4

261

Q8NCG5
LVYLDLSSNKLRSLP

CNOT6L

81

Q96LI5
TRAFLPLLKAQEYIR

PDCD11

211

Q14690
ARLLASKSLLNRYAV

SSR2

21

P43308
AINASRALKSLIPLY

RALGAPA1

1976

Q6GYQ0
LEKSPDLQSLRYALS

UNC13C

2001

Q8NB66
RKRLASNYLNNPLFL

PHF21B

321

Q96EK2
PDTLFSKALNLRYLN

PHLPP2

586

Q6ZVD8
KLSRLTDPNYLCLLD

STYXL1

21

Q9Y6J8
LPKSLQVLRLRDNYL

TLR9

651

Q9NR96
VPYRDSKLTRLLQDS

KIF21A

321

Q7Z4S6
YLSICRKQRALPSLD

MVK

116

Q03426
RYVLSFLRTSKLLLP

KCTD15

111

Q96SI1
PYRDSKLTRLLQDSL

KIF3B

291

O15066
TKYRSLLFNLRDPRN

SPOCD1

661

Q6ZMY3
PRYSKFRSLLEETNL

STAB2

526

Q8WWQ8
LKALQSLYTNRELFP

STAG1

351

Q8WVM7
NYALAKENLALRPRL

VPS37D

61

Q86XT2
KLSVYAALQRQLLSP

PLEC

2846

Q15149
KRLVTLRLPASLAEY

VASN

506

Q6EMK4
LDRLLALNSLYSPKI

PRKDC

2536

P78527
DLKPQNILLSYANRR

ULK2

131

Q8IYT8
LQRIRLSDGSLKLYP

GTF3C2

591

Q8WUA4
NTQPKRIDLYLALLS

TTC37

1291

Q6PGP7
RLNIYKALASPSLIA

TRPC5

196

Q9UL62
RSKRDPDLYQLLQRL

TAC3

36

Q9UHF0
PSRKQQVLDLLTSYL

UBR4

4156

Q5T4S7
RLYQRALQKLPLCAS

ZFC3H1

1926

O60293
RLNIYKALASPSLIA

TRPC4

196

Q9UBN4
SRSLPYKLISLLNEK

MYOF

96

Q9NZM1