Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR10D3 OR51A4 OR51A2 LHCGR OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 OR4A15 OR51I2 MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

4.69e-158848826GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

3.42e-144318819GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR10D3 OR51A4 OR51A2 LHCGR PLXNA3 OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 HLA-DOB OR4A15 OR51I2 UNC5C MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

2.87e-1313538829GO:0004888
GeneOntologyMolecularFunctionodorant binding

OR8D2 OR8B4 OR5A2 OR8B2 OR8B3 OR8B8

2.08e-05127886GO:0005549
GeneOntologyMolecularFunctiontubulin binding

DIP2B STMN3 UNC5C CAMSAP3 TOGARAM1 RP1 CAV3 TUBGCP5

6.01e-04428888GO:0015631
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

2.51e-144328919GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

9.38e-144658919GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

1.99e-134858919GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

7.80e-135248919GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

1.66e-125478919GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 RP1 CAV3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

2.78e-127228921GO:0051606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

4.89e-125828919GO:0050906
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR10D3 OR51A4 OR51A2 LHCGR OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 OR4A15 OR51I2 MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

9.95e-1113958926GO:0007186
GeneOntologyBiologicalProcesssensory perception

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 RP1 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

2.24e-0810728920GO:0007600
GeneOntologyBiologicalProcessregulation of brain-derived neurotrophic factor-activated receptor activity

FAM72D FAM72C FAM72A

3.10e-074893GO:0031551
GeneOntologyBiologicalProcessnegative regulation of brain-derived neurotrophic factor receptor signaling pathway

FAM72D FAM72C FAM72A

7.72e-075893GO:0031549
GeneOntologyBiologicalProcessregulation of brain-derived neurotrophic factor receptor signaling pathway

FAM72D FAM72C FAM72A

2.68e-067893GO:0031548
GeneOntologyBiologicalProcessbrain-derived neurotrophic factor receptor signaling pathway

FAM72D FAM72C FAM72A

2.73e-0514893GO:0031547
GeneOntologyBiologicalProcessnegative regulation of cold-induced thermogenesis

IL15 PLCL2 DOCK7 PLCL1

5.45e-0548894GO:0120163
GeneOntologyBiologicalProcessmicrotubule polymerization or depolymerization

STMN3 CAMSAP3 TOGARAM1 RP1 CAV3 TUBGCP5

8.88e-05168896GO:0031109
GeneOntologyBiologicalProcessregulation of microtubule polymerization or depolymerization

STMN3 CAMSAP3 TOGARAM1 RP1 CAV3

1.05e-04108895GO:0031110
GeneOntologyBiologicalProcessmicrotubule polymerization

CAMSAP3 TOGARAM1 RP1 CAV3 TUBGCP5

1.53e-04117895GO:0046785
GeneOntologyBiologicalProcessmicrotubule-based process

LLGL2 STMN3 SLC9B2 CAMSAP3 DOCK7 TOGARAM1 SAC3D1 CCR6 RP1 CFAP43 CAV3 TUBGCP5 DNAH14 CFAP65

1.67e-0410588914GO:0007017
GeneOntologyBiologicalProcesscytoplasmic microtubule organization

STMN3 CAMSAP3 CAV3 TUBGCP5

1.90e-0466894GO:0031122
GeneOntologyBiologicalProcesstemperature homeostasis

IL15 ZNF516 PLCL2 MC3R DOCK7 PLCL1

2.06e-04196896GO:0001659
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

LLGL2 STMN3 CAMSAP3 DOCK7 TOGARAM1 SAC3D1 RP1 CFAP43 CAV3 TUBGCP5 CFAP65

2.67e-047208911GO:0000226
GeneOntologyBiologicalProcessregulation of microtubule-based process

STMN3 CAMSAP3 TOGARAM1 CCR6 RP1 CFAP43 CAV3

2.77e-04293897GO:0032886
GeneOntologyBiologicalProcessnegative regulation of protein tyrosine kinase activity

FAM72D FAM72C FAM72A

2.90e-0430893GO:0061099
GeneOntologyBiologicalProcessnegative regulation of signaling receptor activity

FAM72D FAM72C FAM72A

3.86e-0433893GO:2000272
GeneOntologyBiologicalProcesspositive regulation of receptor binding

PLCL2 PLCL1

5.07e-048892GO:1900122
GeneOntologyBiologicalProcessregulation of cold-induced thermogenesis

IL15 ZNF516 PLCL2 DOCK7 PLCL1

5.13e-04152895GO:0120161
GeneOntologyBiologicalProcesscold-induced thermogenesis

IL15 ZNF516 PLCL2 DOCK7 PLCL1

5.78e-04156895GO:0106106
GeneOntologyCellularComponentnuclear pore inner ring

NUP155 NUP188

5.36e-053892GO:0044611
MousePhenoincreased germinal center B cell number

FAM72D FAM72C FAM72A S1PR2

8.85e-0631604MP:0008177
MousePhenoabnormal B cell apoptosis

FAM72D FAM72C FAM72A S1PR2

4.76e-0547604MP:0008781
MousePhenoabnormal somatic hypermutation frequency

FAM72D FAM72C FAM72A

6.94e-0519603MP:0004815
MousePhenoabnormal germinal center B cell number

FAM72D FAM72C FAM72A S1PR2

8.88e-0555604MP:0013680
MousePhenoabnormal germinal center B cell morphology

FAM72D FAM72C FAM72A S1PR2

8.88e-0555604MP:0008176
DomainGPCR_Rhodpsn_7TM

OR51A4 OR51A2 LHCGR OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 OR4A15 OR51I2 MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

2.54e-166708725IPR017452
DomainG_PROTEIN_RECEP_F1_2

OR51A4 OR51A2 LHCGR OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 OR4A15 OR51I2 MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

5.19e-166918725PS50262
DomainGPCR_Rhodpsn

OR51A4 OR51A2 LHCGR OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 OR4A15 OR51I2 MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

5.37e-166928725IPR000276
Domain7tm_1

OR51A4 OR51A2 LHCGR OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 OR4A15 OR51I2 MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR8B3 OR8B8

3.54e-156778724PF00001
DomainG_PROTEIN_RECEP_F1_1

OR51A4 OR51A2 LHCGR OR1M1 OR4C3 NPY5R OR10A2 OR8D2 OR8B4 P2RY2 OR51Q1 OR4A15 OR51I2 MC3R OR4Q3 CCRL2 OR5A2 OR2B3 S1PR2 CCR6 OR8B2 OR2B6 OR8B3 OR8B8

4.59e-156858724PS00237
DomainOlfact_rcpt

OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

2.27e-133938718IPR000725
DomainFAM72

FAM72D FAM72C FAM72A

3.89e-074873PF14976
DomainFAM72

FAM72D FAM72C FAM72A

3.89e-074873IPR026768
Domain7TM_GPCR_Srsx

OR51A4 OR51A2 NPY5R OR51I2 MC3R S1PR2

1.38e-05112876SM01381
DomainARM-type_fold

CAND1 EIF2B5 DAAM2 TOGARAM1 HEATR5A FRYL NUP188 ARMCX5 STAG3

2.84e-05339879IPR016024
Domain-

CAND1 DAAM2 TOGARAM1 HEATR5A FRYL ARMCX5 STAG3

7.96e-052228771.25.10.10
DomainARM-like

CAND1 DAAM2 TOGARAM1 HEATR5A FRYL ARMCX5 STAG3

2.66e-04270877IPR011989
DomainPH_12

PLCL2 PLCL1

3.18e-046872PF16457
DomainIG_FLMN

TRIM45 TRIM2

9.42e-0410872SM00557
DomainFilamin

TRIM45 TRIM2

1.15e-0311872PF00630
DomainFILAMIN_REPEAT

TRIM45 TRIM2

1.15e-0311872PS50194
DomainFilamin/ABP280_rpt

TRIM45 TRIM2

1.15e-0311872IPR001298
DomainFilamin/ABP280_repeat-like

TRIM45 TRIM2

1.15e-0311872IPR017868
DomainBbox_C

TRIM45 TRIM2

2.17e-0315872IPR003649
DomainBBC

TRIM45 TRIM2

2.17e-0315872SM00502
DomainPLipase_C_Pinositol-sp_Y

PLCL2 PLCL1

2.17e-0315872IPR001711
DomainEF-hand_like

PLCL2 PLCL1

2.17e-0315872PF09279
DomainPIPLC_Y_DOMAIN

PLCL2 PLCL1

2.17e-0315872PS50008
DomainPI-PLC_fam

PLCL2 PLCL1

2.17e-0315872IPR001192
DomainPLC_EF-hand-like

PLCL2 PLCL1

2.17e-0315872IPR015359
DomainPI-PLC-Y

PLCL2 PLCL1

2.17e-0315872PF00387
DomainPLCYc

PLCL2 PLCL1

2.17e-0315872SM00149
DomainChemokine_rcpt

CCRL2 CCR6

2.47e-0316872IPR000355
DomainPI-PLC-X

PLCL2 PLCL1

3.13e-0318872PF00388
DomainPLCXc

PLCL2 PLCL1

3.13e-0318872SM00148
DomainPIPLC_X_DOMAIN

PLCL2 PLCL1

3.48e-0319872PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCL2 PLCL1

3.48e-0319872IPR000909
DomainHEAT_REPEAT

CAND1 TOGARAM1 HEATR5A

4.27e-0370873PS50077
Domain-

PLCL2 PLCL1

6.00e-03258723.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCL2 PLCL1

6.00e-0325872IPR017946
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

2.09e-144176519M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR10D3 OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

3.64e-116366519M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR51A4 OR51A2 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR2B6 OR8B8

1.85e-103896515M14091
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

LHCGR NPY5R OR10A2 OR8D2 OR8B4 P2RY2 MC3R CCRL2 CCR6 OR8B8

1.20e-081866510MM15994
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

LHCGR NPY5R OR8D2 P2RY2 MC3R CCRL2 OR2B3 CCR6 OR2B6 OR8B8

2.81e-072606510M39397
PathwayWP_GPCRS_ODORANT

OR10D3 OR1M1 OR8B2 OR2B6 OR8B3 OR8B8

8.33e-05157656MM15872
PathwayWP_GPCRS_NONODORANT

LHCGR NPY5R P2RY2 MC3R CCRL2 S1PR2 CCR6

2.15e-04266657MM15843
PathwayWP_GPCRS_PEPTIDE

LHCGR NPY5R MC3R CCR6

3.00e-0470654MM15959
PathwayWP_PEPTIDE_GPCRS

LHCGR NPY5R MC3R CCR6

3.91e-0475654M39696
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

LHCGR NPY5R P2RY2 MC3R CCRL2 S1PR2 CCR6

7.85e-04330657M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

LHCGR NPY5R P2RY2 MC3R CCRL2 S1PR2 CCR6

8.28e-04333657MM14963
PathwayWP_PRIMARY_OVARIAN_INSUFFICIENCY

LHCGR RECQL4 EIF2B5 STAG3 CPEB1

1.23e-03174655M48058
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR10D3 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR8B2 OR2B6 OR8B3 OR8B8

2.20e-13340891411875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR10D3 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR8B2 OR2B6 OR8B3 OR8B8

2.20e-13340891411802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR10D3 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR8B2 OR2B6 OR8B3 OR8B8

2.48e-13343891432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR10D3 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR51Q1 OR4A15 OR51I2 OR4Q3 OR8B2 OR2B6 OR8B3 OR8B8

2.79e-13346891414611657
Pubmed

The human olfactory receptor gene family.

OR10D3 OR1M1 OR4C3 OR10A2 OR8D2 OR8B4 OR4A15 OR51I2 OR4Q3 OR5A2 OR2B3 OR8B2 OR2B6 OR11H2 OR8B3 OR8B8

5.86e-13541891614983052
Pubmed

Fam72a enforces error-prone DNA repair during antibody diversification.

FAM72D FAM72C FAM72A

6.47e-08489334819671
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR1M1 OR10A2 OR8B4 OR4A15 OR5A2 OR2B3 OR8B2 OR8B8

9.91e-0821989812213199
Pubmed

Identification and characterisation of the novel amyloid-beta peptide-induced protein p17.

FAM72D FAM72C FAM72A

1.61e-07589319755123
Pubmed

All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci.

FAM72D FAM72C FAM72A

1.61e-07589326206078
Pubmed

FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.

FAM72D FAM72C FAM72A

3.22e-07689334819670
Pubmed

Characterization of a cluster comprising approximately 100 odorant receptor genes in mouse.

OR8D2 OR8B4 OR8B8

1.92e-061089311130974
Pubmed

Phospholipase C-related inactive protein is implicated in the constitutive internalization of GABAA receptors mediated by clathrin and AP2 adaptor complex.

PLCL2 PLCL1

6.48e-06289217254016
Pubmed

Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of gamma-aminobutyric acid type A receptors.

PLCL2 PLCL1

6.48e-06289219996098
Pubmed

Phospholipase C-related but catalytically inactive protein acts as a positive regulator of insulin signalling in adipocytes.

PLCL2 PLCL1

6.48e-06289234859819
Pubmed

Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice.

PLCL2 PLCL1

6.48e-06289231589911
Pubmed

Identification and characterization of a new phospholipase C-like protein, PLC-L(2).

PLCL2 PLCL1

6.48e-06289210581172
Pubmed

Serum IL-16, not IL-15, was elevated in early second trimester of pregnancy in women who subsequently developed preeclampsia.

IL15 IL16

6.48e-06289217537415
Pubmed

Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface.

PLCL2 PLCL1

6.48e-06289217301177
Pubmed

Involvement of phospholipase C-related inactive protein in the mouse reproductive system through the regulation of gonadotropin levels.

PLCL2 PLCL1

6.48e-06289219553601
Pubmed

Genetic reduction of GABA(A) receptor gamma2 subunit expression potentiates the immobilizing action of isoflurane.

PLCL2 PLCL1

6.48e-06289220097266
Pubmed

Dissociation of heterotrimeric g proteins in cells.

LHCGR NPY5R P2RY2 MC3R S1PR2 CCR6

6.97e-0617989618577758
Pubmed

cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.

FAM72D FAM72C FAM72A

7.21e-06158931741163
Pubmed

The chromosomal distribution of mouse odorant receptor genes.

OR8B2 OR2B6 OR8B3 OR8B8

1.15e-05548948570653
Pubmed

High IL-6 and low IL-15 levels mark the presence of TB infection: A preliminary study.

IL15 IL16

1.94e-05389226878649
Pubmed

Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice.

PLCL2 PLCL1

1.94e-05389223639135
Pubmed

Phospholipase C-related catalytically inactive protein, a novel microtubule-associated protein 1 light chain 3-binding protein, negatively regulates autophagosome formation.

PLCL2 PLCL1

1.94e-05389223399561
Pubmed

Phospholipase C-related catalytically inactive protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase.

PLCL2 PLCL1

1.94e-05389224945349
Pubmed

Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by β-Adrenergic Receptors in Brown Adipocytes.

PLCL2 PLCL1

1.94e-05389226706316
Pubmed

Involvement of PRIP, phospholipase C-related, but catalytically inactive protein, in bone formation.

PLCL2 PLCL1

1.94e-05389221757756
Pubmed

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.

IL15 ZNF516 PLCL2 DOCK7 PLCL1

3.80e-0514689529688375
Pubmed

Distinct effects on mRNA export factor GANP underlie neurological disease phenotypes and alter gene expression depending on intron content.

MCM3AP SAC3D1

3.87e-05489232202298
Pubmed

Phospholipase C-related, but catalytically inactive protein (PRIP) up-regulates osteoclast differentiation via calcium-calcineurin-NFATc1 signaling.

PLCL2 PLCL1

3.87e-05489228341745
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DIP2B SMG8 LLGL2 NUP155 ORC3 RECQL4 EIF2B5 CAMSAP3 DOCK7

4.43e-0565089938777146
Pubmed

Architecture of the linker-scaffold in the nuclear pore.

NUP155 NUP188

9.65e-05689235679425
Pubmed

GABA(A) receptor subunit alteration-dependent diazepam insensitivity in the cerebellum of phospholipase C-related inactive protein knockout mice.

PLCL2 PLCL1

9.65e-05689220412381
Pubmed

Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study.

IL15 NPY5R

1.35e-04789219593212
Pubmed

Modulation of GABA(A) receptor phosphorylation and membrane trafficking by phospholipase C-related inactive protein/protein phosphatase 1 and 2A signaling complex underlying brain-derived neurotrophic factor-dependent regulation of GABAergic inhibition.

PLCL2 PLCL1

1.35e-04789216754670
Pubmed

Susceptibility loci for intracranial aneurysm in European and Japanese populations.

RP1 PLCL1

1.79e-04889218997786
Pubmed

Phospholipase C-related but catalytically inactive proteins regulate ovarian follicle development.

PLCL2 PLCL1

1.79e-04889228360101
Pubmed

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection.

IL15 IL16

2.88e-041089224942581
Pubmed

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase.

CAND1 MARCHF7

4.20e-041289234611473
Pubmed

An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.

NUP155 DOCK7

4.96e-041389230254148
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLXNA3 LLGL2 MCM3AP ZNF516 APEH SAC3D1 ZFYVE26 FRYL NUP188 CFAP43

5.28e-041105891035748872
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

MC3R LAMA3

5.78e-04148929151674
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

DIP2B P2RY2 ORC3 STMN3 UNC5C EIF2B5 RNF10 APEH DNAH14

6.09e-0492589928986522
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MCM3AP PLCL2 DOCK7 DAAM2 HEATR5A STRIP2

6.35e-0440789612693553
Pubmed

Sequence identification of 2,375 human brain genes.

CENPI DAAM2

6.65e-04158921538749
Pubmed

Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb.

OR2B6 OR8B8

7.59e-041689217715346
Pubmed

New GPCRs from a human lingual cDNA library.

OR8D2 OR8B8

8.59e-041789211705801
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

NUP155 MCM3AP NUP188

1.03e-037789324927568
Pubmed

Co-adaptor driven assembly of a CUL3 E3 ligase complex.

CAND1 SEC24B

1.45e-032289235120648
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR1M1 OR8B8

1.72e-03248929119360
Pubmed

Functional interactions between ubiquitin E2 enzymes and TRIM proteins.

TRIM45 TRIM2

2.18e-032789221143188
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

TRIM45 CAMSAP3 FRYL

2.38e-0310389329539633
Pubmed

Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells.

P2RY2 CCR6

2.51e-032989234678150
Pubmed

Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.

TTC39B DOCK7

2.51e-032989220972250
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

TRIM2 RNF10 MARCHF7

2.52e-0310589322493164
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRIM2 MCM3AP ZFC3H1

2.52e-031058939628581
Cytoband11q24.2

OR10D3 OR8D2 OR8B4 OR8B3 OR8B8

1.57e-076389511q24.2
CytobandEnsembl 112 genes in cytogenetic band chr11q24

OR10D3 OR8D2 OR8B4 OR8B2 OR8B3 OR8B8

2.09e-06191896chr11q24
Cytoband11p15.4

OR51A4 OR51A2 OR10A2 OR51Q1 OR51I2

4.60e-0520089511p15.4
GeneFamilyOlfactory receptors, family 8

OR8D2 OR8B4 OR8B2 OR8B3 OR8B8

9.36e-0749665155
GeneFamilyOlfactory receptors, family 51

OR51A4 OR51A2 OR51Q1 OR51I2

1.97e-0544664164
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCL2 PLCL1

2.16e-0319662832
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Metaplastic_Carcinoma-9|TCGA-Breast / Sample_Type by Project: Shred V9

OR10D3 OR8D2 OR8B4 OR8B2 OR8B3 OR8B8

9.22e-09768863d0e3ddac63e805cfa1552ccedeff777aec9d05f
ToppCellcontrol-Lymphoid-B_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IL16 HLA-DOB DOK3 C12orf42 CCR6 DENND1C

1.61e-06181886e414303bb90e5fe7b667c2acf9a50f8694b90e54
ToppCellNS-control-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL16 HLA-DOB DOK3 C12orf42 CCR6 DENND1C

1.66e-061828864b9b55154a79992112c1c467e8752c3cdbb541d9
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB FAM72A C12orf42 CCR6

1.75e-05162885fc313fb2c55957faa8c9ca4023b3fce63527c267
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB FAM72A C12orf42 CCR6

1.75e-05162885002fac3c5c3030950f9eb9e887d59902586d8452
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB FAM72A C12orf42 CCR6

1.75e-0516288508b7f06580d516307516d5475a5dae0fa040f1a4
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB FAM72A C12orf42 CCR6

1.75e-051628851fda21a303a08aff6f97819cd8766cd18784d8bc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 CENPI LAMA3 CAV3 STRIP2

2.03e-05167885108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_THEMIS_PLA2G7|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OR8D2 OR8B4 LAMA3 OR8B2 OR8B3

2.34e-051728851d086e00cd549459d70e1d3b468d5ab6379f3bee
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ORC3 RECQL4 PLCL2 SLC9B2 DENND1C

2.40e-0517388579d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM2 RP1 PLCL1 SLC16A7 DNAH14

2.54e-05175885e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-5|TCGA-Endometrium / Sample_Type by Project: Shred V9

OR10D3 OR8B4 OR8B2 OR8B8

2.57e-0586884df7afc5707bb7296cfed6c4027414505d262af09
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6 STAG3

2.75e-051788856f50e2ee66bd9dc12fd3c9ea70e6d50ff76b02e8
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6 STAG3

2.75e-05178885b132605f237e766a21042b9a65a564d64c4fec10
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6 STAG3

2.75e-0517888599cd5e517855f1a2d6d75fb2d439751f884862c1
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM72D FAM72C HLA-DOB DOK3 STAG3

2.90e-05180885ce2fc270f9d9110c2544083f61936b0b7d3b7eb3
ToppCellSevere-Lymphoid-B|Severe / Condition, Lineage, Cell class and cell subclass

IL16 HLA-DOB C12orf42 CCR6 STAG3

2.90e-0518088567ffaf5096f025c3c61fffe52f6c8a96f120fc6f
ToppCellSevere-Lymphoid-B-|Severe / Condition, Lineage, Cell class and cell subclass

IL16 HLA-DOB C12orf42 CCR6 STAG3

2.90e-05180885fd3eb751704b14ff1500e4bd041441644d233e9c
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-B|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.06e-05182885dc6b5ce410c1a7cade60ae17cbbe8548c088cba8
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

FAM72D FAM72C FAM72A CENPI USP48

3.14e-05183885f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2B IL16 HLA-DOB DOK3 CCR6

3.14e-0518388520f7b6ec2462032eda957a893ca76d5a5a01333d
ToppCellcellseq2-Immune-Lymphocytic_B-Lymphocytic_B-B|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 HLA-DOB DOK3 CCR6 STAG3

3.22e-05184885efcd643324ccd212350dc6a27f40efbb666d557b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM2 RP1 PLCL1 SLC16A7 DNAH14

3.31e-05185885898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell(1)_B_CD27neg|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.40e-05186885646389147189760e9493c4f50f9583959ef0ee26
ToppCell(1)_B_cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.40e-05186885fe0f8e99ca766e004c351835fdbc2dc888dceb62
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.48e-051878858089ae6ee59533a090fe0b19bdd057fba8fa11de
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.57e-051888857b56c680e9f1851cb961b0f8faeeb987685ae36d
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.76e-051908854d15317a554b023fd874e28649af931d238cf83e
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.76e-0519088506ff7fb6b0f7ed1758e9829d4fe6c93d140c005e
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6 STAG3

3.76e-051908859c0dc3c042751b2da772500876b6ff99bf809904
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM2 LLGL2 RP1 PLCL1 SLC16A7

3.85e-05191885963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell3'-Adult-LargeIntestine-Hematopoietic-B_cells-Naive_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.05e-051938858d88f3b0d08f9dbae26ee122dbd43f06e2cc3f67
ToppCell3'-Adult-LargeIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.25e-05195885daacbccf2a6a5ce1f0e3d1743a475076b4411c56
ToppCell5'-Adult-LymphNode-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 HLA-DOB DOK3 C12orf42 STAG3

4.25e-051958858f5dfcdaccb0c8318f90a33519a8d6d98ba22943
ToppCell5'-Adult-LymphNode-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 HLA-DOB DOK3 C12orf42 STAG3

4.25e-05195885e98217f9cf8c9574af66a1d8953101119c89c8a1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM2 LLGL2 RP1 PLCL1 DNAH14

4.25e-051958856477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell(1)_T_cells-(1)_T_cells_Dividing|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

FAM72D FAM72C RECQL4 CENPI SAC3D1

4.25e-05195885cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.36e-05196885e9fe5090452ffdde4bb81b62d57037d823281d00
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.36e-05196885c2e17f3b2217f20bd7f28a1db4aa7d9a95c52a9c
ToppCellBiopsy_Other_PF-Immune-B_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.36e-05196885123cd893fd1ae315a655e909c08528f82e9013ff
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.46e-05197885fd65020089baca78334cecddc96b7a65028c2b7c
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL15 LLGL2 LAMA3 RP1 PLCL1

4.46e-051978858d5097898dd01cedb04cb694cb480c931e08462c
ToppCellBiopsy_Control_(H.)-Immune-B_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.46e-05197885c78e0cf394b9a4e10ebba61f6392d9b5a23db9d8
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DOB DOK3 C12orf42 CCR6 STAG3

4.46e-05197885da175e66d0a743a1b91d46f224b5ff1d37aa5410
ToppCellBiopsy_IPF-Immune-B_cells|Biopsy_IPF / Sample group, Lineage and Cell type

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.57e-051988856a519337a4932a7b685fe7defd3de24fa2016b7d
ToppCellLung_Parenchyma-Severe-Lymphocyte-B-B_cell-B_cell-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.57e-05198885b090c28336b4a0f9acab192885d9c2c2cc5d36e7
ToppCellLung_Parenchyma-Severe-Lymphocyte-B-B_cell|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.57e-051988851637a255b67527fc9f9eb5352fb81cda9168fdfb
ToppCellParenchyma_COVID-19-Immune-TX-B_cells|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.57e-051988853f8c24295ea98c9fbcad2dc5fee17851197e60b3
ToppCellLung_Parenchyma-Severe-Lymphocyte-B-B_cell-B_cell|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.57e-05198885232905d61002fc552e2a8920167dceb550e8eec6
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.57e-0519888579c690d21d3420d0bb1a3b3b4ea2c9aa3810a219
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_cell-B_mature|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.68e-05199885074f21a0075ff6c8e634dc4b12699d371d5f720a
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL15 HLA-DOB CCR6 PLCL1 STRIP2

4.68e-05199885f4ab29f99ce45a3044d2e9f356dc24d3c5e7121f
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 HLA-DOB C12orf42 CCR6 STAG3

4.68e-05199885e9bdc7e9b841ea5aad2f08e7cc9929d824852718
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B TRIM2 UNC5C FRYL PLCL1

4.79e-052008854dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B TRIM2 UNC5C FRYL PLCL1

4.79e-0520088526b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B TRIM2 UNC5C FRYL PLCL1

4.79e-052008851314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B TRIM2 UNC5C FRYL PLCL1

4.79e-052008858b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B TRIM2 UNC5C FRYL PLCL1

4.79e-05200885272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B TRIM2 UNC5C FRYL PLCL1

4.79e-052008855f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FAM72A CENPI APEH DAAM2

2.12e-04148884065177aaa63c0441d312260b43ecdac78c84ad03
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY5R UNC5C DAAM2 PLCL1

2.23e-041508848645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

LHCGR CCRL2 PLCL1 CPEB1

2.28e-041518843f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RECQL4 PLCL2 CCRL2 PLCL1

2.40e-04153884489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

FAM72D FAM72C FAM72A CENPI

2.59e-04156884d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RECQL4 CENPI HEATR5A CPEB1

2.78e-041598847ed659163f45e0c4df4782997c0786900c8186c8
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

IL15 HLA-DOB CCR6 PLCL1

2.85e-04160884bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL16 HLA-DOB DOK3 DENND1C

2.98e-0416288459f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCellCiliated_cells-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

SLC13A4 CFAP43 CPEB1 CFAP65

2.98e-041628845319603f7ba3f48126dcf2ba9ae604be11bf2577
ToppCellHealthy_Control-Lymphoid-Plasma|Healthy_Control / Condition, Lineage, Cell class and cell subclass

HLA-DOB KLHDC7B CCR6 TUBGCP5

3.06e-041638842913ccdd4613472cd82077d4993e1d9f8b223398
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPY5R OR51I2 C12orf42 DAAM2

3.06e-04163884bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPY5R OR51I2 C12orf42 DAAM2

3.06e-041638848e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellHealthy_Control-Lymphoid-Plasma-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

HLA-DOB KLHDC7B CCR6 TUBGCP5

3.06e-04163884b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 DOK3 CENPI CAV3

3.13e-041648841642a67c66eeb77a218e7814e3cfe517d9822955
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 DOK3 CENPI CAV3

3.13e-0416488425758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CCNO RP1 CFAP43 CFAP65

3.20e-041658840c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CCNO RP1 CFAP43 CFAP65

3.20e-0416588482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2B HLA-DOB MCM3AP DOK3

3.27e-041668846a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2B HLA-DOB MCM3AP DOK3

3.27e-041668848d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6

3.27e-04166884a8ba4d51e778634f8a7f47fa0d01a2019f774fb8
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6

3.27e-041668844906c85f52c3751166e296102d524a13b1f438f5
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6

3.27e-0416688404e32bd32165cdf316f2a8709c3662d55cd70391
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DOB DOK3 S1PR2 STAG3

3.43e-0416888408eb1284f9b8bd3e0e4b21bfc2bbee01d35a0bd7
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL16 HLA-DOB DOK3 CCR6

3.43e-04168884943687a33fffd7e19d906b9dd385a126bcea109a
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 HLA-DOB C12orf42 CCR6

3.43e-041688840ecc6503ea249a4b13c42cfec2b024338f7e6080
ToppCellfacs-Heart-LV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 HLA-DOB CCR6 DENND1C

3.58e-041708842491f3849e34b0ccd06015fa59d15e3d7963c76d
ToppCelldroplet-Pancreas-Endocrine-21m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 HLA-DOB DOK3 CCR6

3.58e-041708846086d658a52a1961a1e293cbc3703ae8d309cd11
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FAM72D FAM72C RECQL4 CENPI

3.66e-041718844ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL16 HLA-DOB DOK3 CCR6

3.66e-04171884656a9f407461dbf5c9c0bd234399e1fef6abce2a
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 HLA-DOB DOK3 CCR6

3.75e-041728840bcb960c5ab0d3cbbdf6235b6f28327ea60ba3e3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM2 RP1 PLCL1 SLC16A7

3.75e-041728841565f38266891c3acf49778838de134c5dee5460
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM45 IL15 ZFC3H1 STRIP2

3.91e-041748847be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIM45 IL15 ZFC3H1 STRIP2

4.00e-041758841b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY5R UNC5C DAAM2 STAG3

4.00e-0417588412f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Naive_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 HLA-DOB C12orf42 STAG3

4.00e-04175884d544f24ee33783ed4afb4d7ec079a4484118bb15
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

FAM72D FAM72C CENPI OR2B6

4.00e-0417588474800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCellNS-critical-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRIM45 RECQL4 CENPI CCNO

4.08e-041768847cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCNO RP1 CFAP43 CFAP65

4.08e-04176884dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

FAM72D FAM72C CENPI OR2B6

4.17e-04177884844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FAM72D FAM72C CENPI OR2B6

4.17e-0417788426c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage-naive_B_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HLA-DOB C12orf42 CCR6 CAV3

4.17e-04177884325c10674b18727ddd50bf088a9c6f4ef29aa809
Diseaseperiodontal disease (biomarker_via_orthology)

IL15 IL16

2.01e-048802DOID:3388 (biomarker_via_orthology)
DiseaseTakayasu arteritis

HLA-DOB OR2B3 CAV3 SLC16A7

7.15e-04148804EFO_1001857
Diseaselevel of Phosphatidylcholine (15:0_18:2) in blood serum

DOCK7 CAV3

1.08e-0318802OBA_2045065
Diseasesusceptibility to scarlet fever measurement

HLA-DOB SEC24B FRYL

1.31e-0379803EFO_0008409
Diseasemuscular dystrophy (implicated_via_orthology)

TRIM2 CAV3

1.47e-0321802DOID:9884 (implicated_via_orthology)
Diseasesystemic mastocytosis

TTC39B OR51Q1

2.09e-0325802MONDO_0016586
DiseaseFEV change measurement, response to zileuton

CCR6 SLC16A7

2.09e-0325802EFO_0005921, EFO_0007676
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

TRIM2 DOCK7 RP1

2.50e-0399803EFO_0004611, EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
LCSTNTLPTEYLAIC

C21orf62

106

Q9NYP8
IYLNTLATVLACCPS

CFAP43

426

Q8NDM7
KLIATTHCCINPLLY

CCRL2

286

O00421
TSYSPSLLAICCLAL

CCNO

276

P22674
TEVLAFLHCCLNPVL

CCR6

301

P51684
TLTSCVHASCALLYP

DENND1C

226

Q8IV53
AALAATIHCYCPQLL

CAMSAP3

236

Q9P1Y5
SYIHQVCKGIISCPL

ARMCX5

391

Q6P1M9
ILPLLECACTSTYVN

OR8B8

181

Q15620
YLCDVLPLLQLSCTS

OR8B4

176

Q96RC9
EAYPCLLSVLHHCLQ

DAAM2

371

Q86T65
CGSHLAVVSLCYSPL

OR11H2

256

Q8NH07
LSILDLCYTTTTVPH

OR2B3

66

O76000
LSLLDLCYTTCTVPQ

OR2B6

66

P58173
HYFCDILPLLTLSCS

OR8D2

176

Q9GZM6
VNLLEATLTYPSHCC

LHCGR

266

P22888
CLLYQHLPVTRFPCT

LAMA3

891

Q16787
QITVVLPHSSCELLY

LLGL2

131

Q6P1M3
LPYLASLHCSAITCS

LLGL2

376

Q6P1M3
VGYHVIVPCSSCLLS

FAM72D

81

Q6L9T8
LHPNCTLISLVLVFC

NLRP11

771

P59045
PHLRSISIQCYLCLL

IL15

6

P40933
LCCVSLVAVYPLLSI

CFAP65

1096

Q6ZU64
CPHSLDLCCQTLIQY

MCM3AP

1561

O60318
DALSCLYVILCNHSP

CAND1

496

Q86VP6
RYDLLDCHISICSPQ

EIF2B5

241

Q13144
QQIDYKTLTLHCVCP

PLXNA3

1471

P51805
LCDLYPLLKLACTNT

OR4A15

206

Q8NGL6
LPICRSNVLSHSYCL

OR51I2

166

Q9H344
HIWISIPVCCLYTIS

OR51Q1

26

Q8NH59
VAICCPLHYASILTN

OR51Q1

126

Q8NH59
HLSFIDLCLSCVTVP

OR4Q3

66

Q8NH05
AICNPLLYTVLISHT

OR5A2

126

Q8NGI9
LALYPLITCLLCVSQ

FRYL

311

O94915
SPVHCLTLNEVYTIL

IL16

411

Q14005
LTLNEVYTILSHCDP

IL16

416

Q14005
CLCSVYSGHQSVLIP

DIP2B

1211

Q9P265
VCHLLCPLAQDYTSL

SLC16A7

326

O60669
HLYENLCVLEASPTL

DOK3

396

Q7L591
QTFELTLRSCLYPHI

TUBGCP5

681

Q96RT8
VGYHVIVPCSSCLLS

FAM72A

81

Q5TYM5
TCVSHICAVIIFYLP

OR51A2

241

Q8NGJ7
TCVSHICAVIIFYLP

OR51A4

241

Q8NGJ6
HYLCDILPLLQLSCT

OR8B3

176

Q8NGG8
NLYCSILFLTCISVH

P2RY2

116

P41231
SLHLQDICPLLYSTD

NUP155

856

O75694
IPCLLILCSYTHIAA

OR10A2

196

Q9H208
CLHCIAVALPSYLTP

HEATR5A

466

Q86XA9
VYTCLVDHSSLLSPV

HLA-DOB

196

P13765
CSHEHYVTLNLPCSL

DOCK7

1126

Q96N67
VVYHVIVPCSSCLLS

FAM72C

81

H0Y354
HEATPSSLYQLCRLC

ASB5

286

Q8WWX0
LIEIQCISHIYSLCI

CAV3

111

P56539
CQYVSTHLEPFSLLC

DNAH14

2891

Q0VDD8
LIEPCKCTGSLQYVH

MARCHF7

566

Q9H992
HLVLIITCPTNPYCI

MC3R

261

P41968
PLHCTTLGNTIYCLN

KLHDC7B

531

Q96G42
IDPYLEDSLCHICSS

CPEB1

506

Q9BZB8
SLQDDALCPYVCHLL

CENPI

191

Q92674
HTLCLPVVSSLADVY

SEC24B

996

O95487
ILCSLSETLHINPLY

SLC13A4

531

Q9UKG4
SILLLDYACPVHSCP

S1PR2

251

O95136
LQTLPYLPSCAVQCH

SAC3D1

281

A6NKF1
CSAHLIAILCAYGPI

OR10D3

241

Q8NH80
HYLCDILPLLQLSCT

OR8B2

176

Q96RD0
SLLEHFYSQPLSVLC

ORC3

331

Q9UBD5
YALCGQHCPILTVII

RP1

1911

P56715
HYFCDLTPILRLSCT

OR1M1

176

Q8NGA1
ACDLYPLLEVACTNT

OR4C3

176

Q8NH37
QCLSLLYLFSVCHIL

SMG8

196

Q8ND04
LLPCLHTVCTTCLEQ

TRIM45

41

Q9H8W5
SISVLDYPCCTIQDL

STRIP2

626

Q9ULQ0
ELLATTYTHCRLNCP

RECQL4

936

O94761
ILPLVCLTVSHTSVC

NPY5R

221

Q15761
SEYPLILCLENHCSI

PLCL2

511

Q9UPR0
PCIVEACTSALLAHY

SLC9B2

211

Q86UD5
LCHTSILPIYCELQS

SLC38A6

261

Q8IZM9
SVLSLICSCFYTQPH

STMN3

16

Q9NZ72
SLIPHHQCSQLCLYD

APEH

321

P13798
LLHSCTCVLYTPSNE

ALG2

311

Q9H553
LLHTCQYIVPRCSVS

C12orf42

101

Q96LP6
VASEYPLILCLGNHC

PLCL1

481

Q15111
SSLQAALVVHPCPYC

ZNF516

751

Q92618
ALCCLTILAFHTYIS

TTC39B

351

Q5VTQ0
LLQLLSCFDLHIYCT

STAG3

601

Q9UJ98
HLPLTCEFSICELAL

RNF10

566

Q8N5U6
HTPSLQFLCICSLAY

NUP188

756

Q5SRE5
VNICICSLLTYPSED

TOGARAM1

491

Q9Y4F4
CLQNYIPAHSLTLSC

TRIM2

46

Q9C040
LELRQALYLCPSTCS

USP48

111

Q86UV5
TPCYIQLDAEACHIL

UNC5C

646

O95185
QYLCSIPDSLCLELL

ZFYVE26

561

Q68DK2
YCLCHPLQSSIKETV

ZFC3H1

1751

O60293