Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionacetylcholine receptor regulator activity

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

1.83e-07271926GO:0030548
GeneOntologyMolecularFunctionneurotransmitter receptor regulator activity

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

2.31e-07281926GO:0099602
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH6 DYNC1H1 DNAH10 DNAH12 DNAH17

6.04e-07181925GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH6 DYNC1H1 DNAH10 DNAH12 DNAH17

6.41e-06281925GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH6 DYNC1H1 DNAH10 DNAH12 DNAH17

2.65e-05371925GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF4A DNAH6 DYNC1H1 DNAH10 DNAH12 DNAH17

5.75e-05701926GO:0003777
GeneOntologyMolecularFunctionGTPase activator activity

ABR ADGRB3 TBC1D16 SGSM3 RANBP1 TBC1D15 PREX2 TBC1D17 TBC1D13 TBC1D10A ADAP2

8.55e-0527919211GO:0005096
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH10 KIF4A DNAH6 DYNC1H1 DNAH10 DNAH12 DNAH17

1.46e-041181927GO:0003774
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

SYNJ1 INPP5F INPP5J

2.33e-04131923GO:0034595
GeneOntologyMolecularFunction5S rDNA binding

GTF3C5 MTOR

2.74e-0431922GO:0080084
GeneOntologyMolecularFunctionRNA polymerase III type 2 promoter sequence-specific DNA binding

GTF3C5 MTOR

2.74e-0431922GO:0001003
GeneOntologyMolecularFunctionRNA polymerase III type 1 promoter sequence-specific DNA binding

GTF3C5 MTOR

2.74e-0431922GO:0001002
GeneOntologyMolecularFunctionglucosidase activity

GANC KL AGL

3.66e-04151923GO:0015926
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ABR ADGRB3 TBC1D16 SGSM3 RANBP1 TBC1D15 EPS8L2 PREX2 TBC1D17 TBC1D13 TIAM1 TBC1D10A SPATA13 ADAP2

4.10e-0450719214GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ABR ADGRB3 TBC1D16 SGSM3 RANBP1 TBC1D15 EPS8L2 PREX2 TBC1D17 TBC1D13 TIAM1 TBC1D10A SPATA13 ADAP2

4.10e-0450719214GO:0030695
GeneOntologyMolecularFunctionkinase binding

DUSP12 TRAF3 FRS2 PTK2 SPDYE21 SPDYE5 PLD2 SPDYE2B WWC1 SPDYE18 PRC1 TRAP1 TIAM1 MTOR SKAP1 SPDYE3 SPDYE2 MYOM2 IGSF9B SPDYE6 SPDYE16

4.36e-0496919221GO:0019900
GeneOntologyMolecularFunctionphosphatidylinositol-4-phosphate phosphatase activity

SYNJ1 INPP5F

5.45e-0441922GO:0043812
GeneOntologyMolecularFunctioninositol phosphate phosphatase activity

SYNJ1 INPP5F INPP5J

8.84e-04201923GO:0052745
GeneOntologyMolecularFunctionprocollagen-proline 4-dioxygenase activity

P4HA2 P4HA1

9.02e-0451922GO:0004656
GeneOntologyMolecularFunctionATP-dependent activity

MYH10 KIF4A BPTF DSCC1 DNAH6 DYNC1H1 MOV10 DNAH10 RNF213 MORC4 KATNA1 TRAP1 DNAH12 DNAH17 ATP6V0A4

9.08e-0461419215GO:0140657
GeneOntologyMolecularFunctioniron ion binding

CYP2J2 CYP51A1 TBXAS1 P4HA2 FA2H CYP27C1 P4HA1

1.14e-031661927GO:0005506
GeneOntologyMolecularFunctionO-methyltransferase activity

LCMT2 HENMT1 MEPCE

1.72e-03251923GO:0008171
GeneOntologyMolecularFunctionRNA polymerase III cis-regulatory region sequence-specific DNA binding

GTF3C5 MTOR

1.87e-0371922GO:0000992
GeneOntologyMolecularFunctionalpha-glucosidase activity

GANC AGL

1.87e-0371922GO:0090599
GeneOntologyMolecularFunctionphosphatase activity

DUSP12 ENOPH1 PTK2 SYNJ1 PXYLP1 INPP5F PPP2R1A CTDP1 INPP5J

1.90e-032871929GO:0016791
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

7.86e-08251876GO:0045737
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein kinase activity

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

1.64e-07281876GO:1904031
GeneOntologyBiologicalProcessactivation of GTPase activity

ABR TSC1 TBC1D16 SGSM3 TBC1D15 TBC1D17 TBC1D13 TIAM1 TBC1D10A

6.67e-071091879GO:0090630
GeneOntologyBiologicalProcessregulation of GTPase activity

ABR TSC1 PTK2 TBC1D16 SGSM3 TBC1D15 PKP4 PREX2 TBC1D17 TBC1D13 TIAM1 TBC1D10A MTOR ADAP2

2.41e-0633518714GO:0043087
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

ABR TSC1 TBC1D16 SGSM3 TBC1D15 PKP4 PREX2 TBC1D17 TBC1D13 TIAM1 TBC1D10A ADAP2

2.46e-0624418712GO:0043547
GeneOntologyBiologicalProcessregulation of cell projection organization

LZTS3 ADGRB3 TSC1 PTK2 TBC1D16 SGSM3 MOV10 RANBP1 TBC1D15 EPS8L2 NEDD4L NRCAM INPP5F KATNA1 TBC1D17 TBC1D13 TIAM1 TBC1D10A MTOR LRP1 INPP5J

3.90e-0586318721GO:0031344
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

ABR TSC1 PTK2 TBC1D16 SPDYE5 SGSM3 DSCC1 SPDYE2B TBC1D15 PKP4 SKP1 WDR59 PREX2 TBC1D17 TBC1D13 TIAM1 TBC1D10A MTOR SPDYE3 SPDYE2 SPDYE6 ADAP2 SPDYE16

5.98e-05102818723GO:0043085
GeneOntologyBiologicalProcessmodification of postsynaptic actin cytoskeleton

MYH10 SPTB PTK2 TIAM1

6.03e-05241874GO:0098885
GeneOntologyBiologicalProcesscholangiocyte proliferation

MKI67 PKHD1 MTOR

8.40e-05101873GO:1990705
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

LZTS3 ADGRB3 TSC1 PTK2 TBC1D16 SGSM3 RANBP1 TBC1D15 EPS8L2 NEDD4L NRCAM INPP5F KATNA1 TBC1D17 TBC1D13 TIAM1 TBC1D10A MTOR LRP1 INPP5J

8.92e-0584618720GO:0120035
GeneOntologyBiologicalProcessregulation of modification of postsynaptic actin cytoskeleton

MYH10 PTK2 TIAM1

1.52e-04121873GO:1905274
GeneOntologyBiologicalProcessregulation of cell cycle

TSC1 USP19 OVOL2 FBXO6 MKI67 PKHD1 ANAPC16 SPDYE5 SGSM3 UHRF2 SPDYE2B DYNC1H1 ANAPC13 RANBP1 MYBBP1A PKP4 PRC1 PRPF40A PPP2R1A SPDYE3 SPDYE2 MEPCE PRKDC SPDYE6 SPDYE16

1.79e-04125618725GO:0051726
GeneOntologyCellularComponentaxonemal dynein complex

DNAH6 DNAH10 DNAH12 DNAH17

7.20e-05251904GO:0005858
GeneOntologyCellularComponentinner dynein arm

DNAH6 DNAH10 DNAH12

8.46e-05101903GO:0036156
GeneOntologyCellularComponentdynein complex

DNAH6 DYNC1H1 DNAH10 DNAH12 DNAH17

1.30e-04541905GO:0030286
GeneOntologyCellularComponentprocollagen-proline 4-dioxygenase complex

P4HA2 P4HA1

2.45e-0431902GO:0016222
GeneOntologyCellularComponentglutamatergic synapse

MYH10 ABR LZTS3 SPTB ADGRB3 PTK2 SYNJ1 ANO2 NEDD4L NRCAM PCLO GRIA3 YES1 PPP2R1A PPP2R1B TIAM1 MTOR LRP1

4.90e-0481719018GO:0098978
GeneOntologyCellularComponentmicrotubule associated complex

KIF4A DNAH6 DYNC1H1 DNAH10 KATNA1 DNAH12 DNAH17

6.90e-041611907GO:0005875
GeneOntologyCellularComponentpostsynaptic specialization

ABR LZTS3 ADGRB3 TSC1 SORCS2 NRCAM PCLO PKP4 GRIA3 YES1 TIAM1 LRP1 IGSF9B

7.23e-0450319013GO:0099572
GeneOntologyCellularComponentpostsynaptic density

ABR LZTS3 ADGRB3 TSC1 SORCS2 NRCAM PCLO PKP4 GRIA3 TIAM1 LRP1 IGSF9B

8.99e-0445119012GO:0014069
DomainSpy1

SPDYE21 SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

3.10e-12111897PF11357
DomainSpeedy

SPDYE21 SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

3.10e-12111897IPR020984
DomainHEAT_REPEAT

HEATR5B HEATR4 ECPAS PPP2R1A PPP2R1B MTOR PRKDC

6.80e-06701897PS50077
DomainWW

TCERG1 WWC1 NEDD4L FNBP4 GAS7 PRPF40A

7.54e-06471896PF00397
DomainETS_DOMAIN_1

ETS2 ETV3 ETV5 ETV3L FEV

8.19e-06281895PS00345
DomainETS_DOMAIN_2

ETS2 ETV3 ETV5 ETV3L FEV

8.19e-06281895PS00346
DomainEts

ETS2 ETV3 ETV5 ETV3L FEV

8.19e-06281895PF00178
DomainETS

ETS2 ETV3 ETV5 ETV3L FEV

8.19e-06281895SM00413
DomainEts_dom

ETS2 ETV3 ETV5 ETV3L FEV

8.19e-06281895IPR000418
DomainETS_DOMAIN_3

ETS2 ETV3 ETV5 ETV3L FEV

8.19e-06281895PS50061
DomainWW

TCERG1 WWC1 NEDD4L FNBP4 GAS7 PRPF40A

8.55e-06481896SM00456
DomainDynein_heavy_chain_D4_dom

DNAH6 DYNC1H1 DNAH10 DNAH12

9.39e-06141894IPR024317
DomainDynein_heavy_dom-2

DNAH6 DYNC1H1 DNAH10 DNAH12

9.39e-06141894IPR013602
DomainDHC_N2

DNAH6 DYNC1H1 DNAH10 DNAH12

9.39e-06141894PF08393
DomainATPase_dyneun-rel_AAA

DNAH6 DYNC1H1 DNAH10 DNAH12

9.39e-06141894IPR011704
DomainAAA_8

DNAH6 DYNC1H1 DNAH10 DNAH12

9.39e-06141894PF12780
DomainAAA_5

DNAH6 DYNC1H1 DNAH10 DNAH12

9.39e-06141894PF07728
DomainTBC

TBC1D16 SGSM3 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

9.66e-06491896SM00164
DomainWW_DOMAIN_1

TCERG1 WWC1 NEDD4L FNBP4 GAS7 PRPF40A

1.22e-05511896PS01159
DomainWW_DOMAIN_2

TCERG1 WWC1 NEDD4L FNBP4 GAS7 PRPF40A

1.22e-05511896PS50020
DomainDHC_fam

DNAH6 DYNC1H1 DNAH10 DNAH12

1.27e-05151894IPR026983
DomainDynein_heavy

DNAH6 DYNC1H1 DNAH10 DNAH12

1.27e-05151894PF03028
DomainDynein_heavy_dom

DNAH6 DYNC1H1 DNAH10 DNAH12

1.27e-05151894IPR004273
DomainWW_dom

TCERG1 WWC1 NEDD4L FNBP4 GAS7 PRPF40A

1.37e-05521896IPR001202
DomainRabGAP-TBC

TBC1D16 SGSM3 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

1.53e-05531896PF00566
DomainRab-GTPase-TBC_dom

TBC1D16 SGSM3 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

1.90e-05551896IPR000195
DomainTBC_RABGAP

TBC1D16 SGSM3 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

1.90e-05551896PS50086
DomainHEAT

HEATR4 ECPAS PPP2R1A PPP2R1B MTOR PRKDC

2.59e-05581896IPR000357
DomainPP2A_A_meta

PPP2R1A PPP2R1B

1.02e-0421892IPR031090
DomainDUF3548

TBC1D15 TBC1D17

1.02e-0421892IPR021935
DomainDUF5050

LRP1B LRP1

1.02e-0421892IPR032485
DomainDUF3548

TBC1D15 TBC1D17

1.02e-0421892PF12068
DomainETV3

ETV3 ETV3L

1.02e-0421892IPR032929
DomainDUF5050

LRP1B LRP1

1.02e-0421892PF16472
DomainHEAT

HEATR4 ECPAS PPP2R1A PPP2R1B PRKDC

1.21e-04481895PF02985
DomainARM-type_fold

IFT172 HEATR5B MYBBP1A HEATR4 PKP4 ECPAS PPP2R1A PPP2R1B ARVCF MTOR PRKDC PPP6R3

1.81e-0433918912IPR016024
DomainSMP_LBD

ESYT2 ESYT1

3.04e-0431892PF17047
DomainP4Ha_N

P4HA2 P4HA1

3.04e-0431892PF08336
DomainSMP_LBD

ESYT2 ESYT1

3.04e-0431892IPR031468
DomainPro_4_hyd_alph_N

P4HA2 P4HA1

3.04e-0431892IPR013547
DomainDynein_HC_stalk

DNAH6 DYNC1H1 DNAH10

3.42e-04141893IPR024743
DomainMT

DNAH6 DYNC1H1 DNAH10

3.42e-04141893PF12777
DomainARM-like

HEATR5B HEATR4 PKP4 ECPAS PPP2R1A PPP2R1B ARVCF MTOR PRKDC PPP6R3

4.40e-0427018910IPR011989
Domain-

HEATR5B HEATR4 PKP4 ECPAS PPP2R1A PPP2R1B ARVCF MTOR PRKDC

4.44e-0422218991.25.10.10
Domain-

TCERG1 PRPF40A

6.03e-04418921.10.10.440
DomainVWA_2

INTS6L INTS6

9.98e-0451892PF13519
DomainSyja_N

SYNJ1 INPP5F

9.98e-0451892PF02383
DomainFATC

MTOR PRKDC

9.98e-0451892PF02260
DomainSAC

SYNJ1 INPP5F

9.98e-0451892PS50275
DomainSAC_dom

SYNJ1 INPP5F

9.98e-0451892IPR002013
DomainFF_domain

TCERG1 PRPF40A

1.49e-0361892IPR002713
DomainFF

TCERG1 PRPF40A

1.49e-0361892PS51676
DomainFF

TCERG1 PRPF40A

1.49e-0361892PF01846
DomainFF

TCERG1 PRPF40A

1.49e-0361892SM00441
DomainFAT

MTOR PRKDC

1.49e-0361892PS51189
DomainFATC

MTOR PRKDC

1.49e-0361892PS51190
DomainFAT

MTOR PRKDC

1.49e-0361892PF02259
DomainPIK-rel_kinase_FAT

MTOR PRKDC

1.49e-0361892IPR003151
DomainFATC_dom

MTOR PRKDC

1.49e-0361892IPR003152
DomainPIK_FAT

MTOR PRKDC

1.49e-0361892IPR014009
DomainFATC

MTOR PRKDC

1.49e-0361892SM01343
DomainCyt_P450_CS

CYP2J2 CYP51A1 TBXAS1 CYP27C1

2.02e-03531894IPR017972
DomainAnoct_dimer

ANO2 ANO7

2.07e-0371892PF16178
DomainAnoct_dimer

ANO2 ANO7

2.07e-0371892IPR032394
DomainApoL

APOL3 APOL4

2.07e-0371892PF05461
DomainApoL

APOL3 APOL4

2.07e-0371892IPR008405
DomainPlakophilin/d_Catenin

PKP4 ARVCF

2.07e-0371892IPR028435
DomainC2

ABR ESYT2 WWC1 NEDD4L ESYT1 PCLO

2.18e-031311896PF00168
DomainCYTOCHROME_P450

CYP2J2 CYP51A1 TBXAS1 CYP27C1

2.64e-03571894PS00086
DomainDHC_N1

DYNC1H1 DNAH10

2.74e-0381892PF08385
DomainINT_SG_DDX_CT_C

INTS6L INTS6

2.74e-0381892PF15300
DomainINT_SG_DDX_CT_C

INTS6L INTS6

2.74e-0381892IPR029307
DomainDynein_heavy_dom-1

DYNC1H1 DNAH10

2.74e-0381892IPR013594
Domain-

CYP2J2 CYP51A1 TBXAS1 CYP27C1

2.81e-035818941.10.630.10
Domainp450

CYP2J2 CYP51A1 TBXAS1 CYP27C1

2.81e-03581894PF00067
DomainCyt_P450

CYP2J2 CYP51A1 TBXAS1 CYP27C1

3.18e-03601894IPR001128
PathwayREACTOME_TBC_RABGAPS

TSC1 TBC1D16 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

1.41e-06351466MM15494
PathwayREACTOME_TBC_RABGAPS

TSC1 TBC1D16 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

5.68e-06441466M27748
Pubmed

Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

2.46e-129196636272447
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

4.93e-1113196615611625
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

MYH10 IFT172 PRPF6 GTF3C5 USP19 ESYT2 DNAJC10 TCERG1 DYNC1H1 MYBBP1A TBC1D15 ESYT1 RCN2 ECPAS PPP2R1A TRAP1 MTOR SEC23IP EIF3B PRKDC PPP6R3

1.10e-106381962133239621
Pubmed

Characterization of a new family of cyclin-dependent kinase activators.

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6 SPDYE16

3.49e-1017196615574121
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

DUSP12 USP11 MKI67 HEATR5B ILVBL DYNC1H1 DOP1B RANBP1 MYBBP1A RCN2 SKP1 PPP2R1A PPP2R1B INTS6 TRAP1 P4HA1 EIF3B PRKDC PPP6R3

7.87e-105731961928330616
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRAF3 MYH10 ABR LZTS3 ADGRB3 KIF4A TSC1 PTK2 SYNJ1 DYNC1H1 MYBBP1A NEDD4L NRCAM PKP4 GRIA3 SKP1 PPP2R1A ARVCF MTOR SEC23IP LRP1 SPATA13 PCNT

6.58e-099631962328671696
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH6 DYNC1H1 DNAH10 DNAH12 DNAH17

1.04e-081419659373155
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DUSP12 TRAF3 USP11 IFT172 ESYT2 DNAJC10 AGL TTC13 PLD2 ABTB2 WWC1 TBC1D15 ESYT1 RCN2 PUSL1 ECPAS PPP2R1A PPP2R1B MTOR LRP1 PRKDC PPP6R3

3.84e-089741962228675297
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

TRAF3 MYH10 PRPF6 ESYT2 FBXO6 DNAJC10 MKI67 ILVBL DYNC1H1 MOV10 RANBP1 TBC1D15 ESYT1 RCN2 RNF213 ECPAS SKP1 YES1 LIFR PPP2R1A PPP2R1B TRAP1 MTOR EIF3B PRKDC PCK2 PPP6R3

4.67e-0814401962730833792
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

ABR USP11 GTF3C5 ESYT2 SAFB MKI67 ANAPC16 ILVBL DYNC1H1 MOV10 PKP4 PRPF40A LIG4 MTOR MEPCE EIF3B PPP6R3 PCNT

5.62e-086701961822990118
Pubmed

Global landscape of HIV-human protein complexes.

USP11 FBXO6 DYNC1H1 SUMF2 P4HA2 RANBP1 TBC1D15 NEDD4L CHAF1A RCN2 RNF213 SKP1 MEPCE EIF3B PRKDC

5.86e-084571961522190034
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYH10 USP11 KIF4A GTF3C5 BPTF ESYT2 TCERG1 AGL DYNC1H1 MOV10 SFMBT1 ESYT1 CHAF1A PUSL1 PRC1 ECPAS SKP1 LIG4 P4HA1 LRP1

9.86e-088571962025609649
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MYH10 PRPF6 GTF3C5 USP19 SAFB TCERG1 MKI67 DYNC1H1 RANBP1 MYBBP1A TBC1D15 DNAH10 NSD2 ESYT1 CHAF1A PCLO RCN2 PRC1 ECPAS PRPF40A PPP2R1A TRAP1 MTOR SEC23IP EIF3B PRKDC

1.44e-0714251962630948266
Pubmed

Functional dissection of Rab GTPases involved in primary cilium formation.

TBC1D16 SGSM3 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

1.52e-0743196617646400
Pubmed

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

TBC1D16 SGSM3 TBC1D15 TBC1D17 TBC1D13 TBC1D10A

1.52e-0743196619077034
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

CMBL MYH10 PRPF6 ILVBL RANBP1 MYBBP1A NEDD4L ESYT1 PCLO INPP5F ECPAS YES1 PPP2R1A PPP2R1B PPP6R3

1.77e-074981961536634849
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYH10 USP11 KIF4A PRPF6 BPTF MKI67 DYNC1H1 MOV10 MYBBP1A NSD2 ECPAS PRPF40A PPP2R1A MTOR PRKDC PPP6R3 PCNT

2.08e-076531961722586326
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

ETV3 PRPF6 GTF3C5 ESYT2 DNAJC10 MKI67 ILVBL MOV10 MYBBP1A RCN2 SKP1 PRPF40A PPP2R1A INTS6 P4HA1 MEPCE PRKDC

2.17e-076551961735819319
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TRAF3 MYH10 CYP51A1 BPTF DNAJC10 MKI67 TTC13 ILVBL DYNC1H1 SUMF2 P4HA2 RANBP1 TBC1D15 EPS8L2 NEDD4L ESYT1 RCN2 GXYLT1 YES1 TBC1D13 PPP2R1A P4HA1 PRKDC PPP6R3

3.54e-0712971962433545068
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

KIF4A PRPF6 BPTF SAFB TCERG1 DYNC1H1 CHAF1A RNF213 PRC1 PPP2R1A P4HA1 PRKDC

4.66e-073321961232786267
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

IFT172 ADGRB3 PTK2 SAFB DNAJC10 TCERG1 SYNJ1 MYBBP1A SKP1 PREX2 PPP2R1A INTS6 IGSF9B INPP5J

5.97e-074751961431040226
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KIF4A GTF3C5 BPTF TCERG1 SYNJ1 DYNC1H1 RANBP1 MYBBP1A TBC1D15 FNBP4 PRPF40A PPP2R1A SEC23IP PRKDC PPP6R3

6.08e-075491961538280479
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

USP11 CYP51A1 PRPF6 GTF3C5 ESYT2 TCERG1 DYNC1H1 TBC1D15 ESYT1 ECPAS PPP2R1A INTS6 TRAP1 SEC23IP PPP6R3

7.78e-075601961535241646
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

FBXO6 DOP1B RANBP1 RCN2 RNF213 PPP2R1A PPP2R1B MTOR PRKDC

1.07e-06183196923956138
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

USP11 KIF4A PRPF6 GTF3C5 BPTF SAFB TCERG1 MKI67 UHRF2 MYBBP1A NSD2 CHAF1A RNF213 PRC1 ECPAS PRPF40A PPP2R1A MEPCE EIF3B PRKDC

1.37e-0610141962032416067
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

ABR USP19 STAT6 SAFB DNAJC10 AGL WWC1 SUMF2 EPS8L2 NSD2 PKP4 ST3GAL3 TBC1D17 LIG4 TRAP1 CTDP1 EIF3B SPDYE16 ALG13

1.41e-069251961928986522
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP11 FCSK BPTF DNAJC10 ILVBL WWC1 NSD2 CHAF1A PKP4 IYD RCN2 RNF213 GAS7 SKP1 PRPF40A INTS6 P4HA1 MEPCE LRP1 CLMP ALG13

1.55e-0611161962131753913
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

CYP51A1 USP19 ESYT2 TTC13 HEATR5B ILVBL DYNC1H1 SUMF2 MYBBP1A TBC1D15 ESYT1 ECPAS PPP2R1A P4HA1 MTOR SEC23IP PRKDC PCK2 PPP6R3

1.84e-069421961931073040
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYH10 PTK2 SAFB AGL PKHD1 MYBBP1A FNBP4 TBC1D17 PRKDC

2.41e-06202196924639526
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYH10 USP11 KIF4A TSC1 PRPF6 GTF3C5 PTK2 SAFB TCERG1 MKI67 DYNC1H1 MOV10 RANBP1 MYBBP1A ESYT1 PKP4 SKP1 WDR59 PPP2R1A ARVCF EIF3B PRKDC PCK2

2.65e-0613531962329467282
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

CMBL CYP51A1 GTF3C5 USP19 TCERG1 HEATR5B DYNC1H1 RANBP1 TBC1D15 ESYT1 ECPAS PPP2R1A TRAP1 SEC23IP MEPCE PRKDC PCK2 PPP6R3

2.78e-068781961837223481
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

USP11 CYP51A1 PRPF6 GTF3C5 ESYT2 DNAJC10 TCERG1 AGL ILVBL DYNC1H1 MYBBP1A TBC1D15 ESYT1 RCN2 MORC4 SKP1 PPP2R1A PPP2R1B TRAP1 EIF3B PRKDC PPP6R3

2.79e-0612571962237317656
Pubmed

Defining the membrane proteome of NK cells.

ABR CYP51A1 KIF4A PRPF6 ESYT2 DNAJC10 MKI67 HEATR5B ILVBL DYNC1H1 MYBBP1A ESYT1 RNF213 ECPAS PRPF40A TRAP1 P4HA1 MTOR APOL3 PRKDC PCNT

3.15e-0611681962119946888
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MYH10 CYP51A1 PRPF6 GTF3C5 BPTF SAFB DNAJC10 TCERG1 DYNC1H1 MYBBP1A NEDD4L NSD2 FNBP4 RCN2 SKP1 PRPF40A INTS6 P4HA1 EIF3B PRKDC

3.64e-0610821962038697112
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

USP11 CYP51A1 FRS2 PRPF6 HSPA12B LCMT2 ESYT2 DNAJC10 TTC13 CCDC97 MYBBP1A TBC1D15 ESYT1 PKP4 FNBP4 RCN2 YES1 PRPF40A TBC1D17 LIFR TIAM1 P4HA1 PPP6R3 PCNT

3.83e-0614871962433957083
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KIF4A PRPF6 GTF3C5 BPTF ESYT2 SAFB TCERG1 MKI67 ANAPC16 ILVBL SFMBT1 MYBBP1A NSD2 FA2H CHAF1A FNBP4 PRC1 SKP1 PRPF40A PPP2R1A INTS6 PRKDC

4.43e-0612941962230804502
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

LZTS3 PTK2 SYNJ1 DYNC1H1 NRCAM PCLO PKP4 GRIA3 PPP2R1A MTOR

4.93e-062811961028706196
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

TSC1 PRPF6 DNAJC10 FNBP4 ECPAS SKP1 PPP2R1A LOXHD1 DNAH12 P4HA1 MEPCE MYOM2 CDH7

5.58e-064971961336774506
Pubmed

Genetic control of autoimmune myocarditis mediated by myosin-specific antibodies.

SERPINA3 TRAF3 DYNC1H1

6.07e-06719639887344
Pubmed

Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.

MAN2A2 GANC GXYLT1 ST3GAL3 ALG13

6.14e-064619652649653
Pubmed

Human transcription factor protein interaction networks.

TRAF3 MYH10 USP11 ETV3 ETV5 BPTF TCERG1 MKI67 ILVBL DYNC1H1 MOV10 RANBP1 MYBBP1A DNAH10 RCN2 MORC4 SKP1 PRPF40A PPP2R1A FEV EIF3B PAX9 PPP6R3

6.48e-0614291962335140242
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

MYH10 KIF4A PRPF6 TCERG1 SYNJ1 MKI67 CCDC97 DYNC1H1 FNBP4 SKP1 PRPF40A MEPCE EIF3B

6.76e-065061961330890647
Pubmed

Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.

MYH10 DYNC1H1 MYBBP1A TRAP1 PRKDC PCNT

7.28e-0682196630274258
Pubmed

The DNA sequence of human chromosome 7.

CYP51A1 SNX10 SPDYE21 SPDYE5 SPDYE2B TBXAS1 SUMF2 NRCAM PCLO SPDYE3 SPDYE6 SPDYE16

8.69e-064411961212853948
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

MYH10 KIF4A PRPF6 SAFB TCERG1 MKI67 NSD2 PRPF40A TRAP1 P4HA1 EIF3B PRKDC

8.69e-064411961231239290
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MYH10 USP11 PRPF6 GTF3C5 TCERG1 AGL DYNC1H1 MOV10 RANBP1 MYBBP1A RCN2 MORC4 ECPAS SKP1 PRPF40A PPP2R1A TRAP1 P4HA1 EIF3B PRKDC

8.80e-0611491962035446349
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

MYH10 TSC1 PRPF6 GTF3C5 UHRF2 DYNC1H1 MYBBP1A EPS8L2 RCN2 RNF213 SKP1 PPP2R1A PRKDC PCK2

9.04e-066011961433658012
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

KIF4A PRPF6 GTF3C5 MKI67 ANAPC16 CCDC97 DYNC1H1 MOV10 ANAPC13 RANBP1 MYBBP1A RCN2 PRC1 SKP1 YES1 PPP2R1A PPP2R1B TRAP1 EIF3B PRKDC

9.49e-0611551962020360068
Pubmed

ETS-dependent regulation of a distal Gata4 cardiac enhancer.

ETS2 ETV3 ETV5 FEV

9.52e-0624196422056786
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

MYH10 CYP51A1 PRPF6 ENOPH1 USP19 ESYT2 SAFB AGL ILVBL RANBP1 MYBBP1A ESYT1 RNF213 ECPAS YES1 PRPF40A PPP2R1A PPP2R1B P4HA1 MTOR LRP1 PRKDC

1.05e-0513671962232687490
Pubmed

Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.

MAN2A2 GANC GXYLT1 ALG13

1.13e-052519642283726
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTB DNAJC10 DNAH6 DNAH10 RNF213 TRAP1 EIF3B PCNT

1.19e-05187196826460568
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

CMBL ABR FRS2 ESYT2 TCERG1 DYNC1H1 MYBBP1A TBC1D15 ESYT1 RCN2 ECPAS PRPF40A PPP2R1A SEC23IP PRKDC

1.32e-057081961539231216
Pubmed

Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.

MAN2A2 GANC GXYLT1 ALG13

1.33e-052619648218172
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP11 IFT172 SPTB ADGRB3 ETS2 LRP1B PTK2 STAT6 TCERG1 SYNJ1 SGSM3 DYNC1H1 DOP1B NRCAM GAS7 WDR59 TIAM1 SEC23IP LRP1 PRKDC PCNT

1.34e-0512851962135914814
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TRAF3 ABR ADGRB3 PTK2 SYNJ1 DYNC1H1 GRIA3 ARVCF LRP1

1.39e-05251196927507650
Pubmed

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.

MYH10 SAFB MKI67 DYNC1H1 RANBP1 MYBBP1A ESYT1 RCN2 PRPF40A PPP2R1A TRAP1 PRKDC

1.41e-054631961234901782
Pubmed

Essential role for the SLK protein kinase in embryogenesis and placental tissue development.

ETV5 PTK2 MKI67

1.44e-059196324868594
Pubmed

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

RANBP1 ESYT1 RCN2 PPP2R1A PPP2R1B TIAM1 P4HA1 PRKDC

1.61e-05195196817110338
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MAN2A2 CYP51A1 KIF4A LRP1B USP19 XYLT2 DNAJC10 TTC13 SUMF2 P4HA2 RANBP1 NEDD4L ESYT1 RCN2 RNF213 GXYLT1 LIFR P4HA1 LRP1 PPP6R3

1.66e-0512011962035696571
Pubmed

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.

XIRP1 MYH10 PRPF6 DNAJC10 SYNJ1 MYBBP1A SKP1 P4HA1 EIF3B

1.79e-05259196931162944
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

ABR USP11 GTF3C5 TCERG1 ANAPC16 MOV10 PCLO RCN2 SKP1 PPP2R1A PPP2R1B TRAP1 PRKDC PPP6R3

1.79e-056391961423443559
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

KIF4A GTF3C5 ESYT2 ILVBL DYNC1H1 ESYT1 RCN2 SKP1 PPP2R1A PRKDC PPP6R3

1.84e-053991961137536630
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

MYH10 PRPF6 ESYT2 SAFB TCERG1 MKI67 ILVBL DYNC1H1 MOV10 RANBP1 MYBBP1A ESYT1 CHAF1A PRPF40A TRAP1 P4HA1 MEPCE ALDH4A1 EIF3B PRKDC PCK2

1.95e-0513181962130463901
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYH10 ESYT2 DYNC1H1 MOV10 RANBP1 TBC1D15 ESYT1 RCN2 SKP1 PPP2R1A PPP2R1B MTOR PRKDC PPP6R3

2.05e-056471961426618866
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FRS2 FAM186B AGL PKHD1 DYNC1H1 IQCE DOP1B PCLO RNF213 ECPAS LOXHD1 P4HA1 IGSF9B PRKDC SPDYE16

2.07e-057361961529676528
Pubmed

ETS-family genes in pancreatic development.

ETS2 ETV3 ETV5 FEV

2.08e-0529196417907201
Pubmed

Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

ETS2 ETV3 ETV5 FEV

2.08e-0529196426097038
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MYH10 IFT172 TSC1 USP19 DYNC1H1 DOP1B NEDD4L NRCAM ZSWIM6 SPATA13 PCNT

2.20e-054071961112693553
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH10 FAM47B TSC1 PRPF6 BPTF SAFB DNAJC10 PKHD1 DNAH6 RANBP1 MYBBP1A NSD2 CHAF1A PCLO GRIA3 LIG4 TRAP1 SEC23IP MYOM2 PRKDC SPATA13 PCNT

2.37e-0514421962235575683
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

MYH10 KIF4A TSC1 SAFB TCERG1 SYNJ1 MKI67 RANBP1 MYBBP1A ESYT1 PRPF40A TRAP1 SEC23IP MEPCE PRKDC PPP6R3 PCNT

2.45e-059341961733916271
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

MYH10 PRPF6 BPTF DNAJC10 AGL MKI67 MOV10 MYBBP1A ECPAS SEC23IP EIF3B PPP6R3

2.66e-054941961226831064
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RBBP8NL GTF3C5 SYNJ1 SFMBT1 TBC1D15 INPP5F MORC4 ECPAS SEC23IP LRP1 PCNT

2.81e-054181961134709266
Pubmed

Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity.

ETS2 ETV5 FEV

2.81e-0511196320610757
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

USP11 ESYT2 DYNC1H1 RCN2 RNF213 SKP1 PPP2R1A PPP2R1B TRAP1 PRKDC

2.83e-053441961036282215
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

CMBL USP11 PRPF6 DNAJC10 AGL HEATR5B DYNC1H1 MOV10 MYBBP1A RCN2 PUSL1 SKP1 YES1 PPP2R1A TRAP1 MEPCE EIF3B PRKDC SPATA13

3.15e-0511531961929845934
Pubmed

Mammalian target of rapamycin signaling inhibition ameliorates vascular calcification via Klotho upregulation.

KL MTOR

3.16e-052196226061549
Pubmed

Critical role for hypothalamic mTOR activity in energy balance.

TSC1 MTOR

3.16e-052196219356717
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1B LRP1

3.16e-052196215963947
Pubmed

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy.

TBC1D15 TBC1D17

3.16e-052196224569479
Pubmed

Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets.

P4HA2 P4HA1

3.16e-052196238081527
Pubmed

TSC/MTOR mutated renal cell carcinoma with leiomyomatous stroma is a distinct entity: a comprehensive study of 12 cases.

TSC1 MTOR

3.16e-052196236592877
Pubmed

alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure.

PPP2R1A PPP2R1B

3.16e-05219622159327
Pubmed

Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells.

PTK2 YES1

3.16e-052196225868388
Pubmed

Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth.

P4HA2 P4HA1

3.16e-052196234218269
Pubmed

Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.

TSC1 MTOR

3.16e-052196226991739
Pubmed

Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.

P4HA2 P4HA1

3.16e-05219629211872
Pubmed

Absence of Sac2/INPP5F enhances the phenotype of a Parkinson's disease mutation of synaptojanin 1.

SYNJ1 INPP5F

3.16e-052196232424101
Pubmed

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.

TSC1 MTOR

3.16e-052196219934433
Pubmed

Human capping enzyme promotes formation of transcriptional R loops in vitro.

CTDP1 MEPCE

3.16e-052196217978174
Pubmed

DNA-dependent protein kinase interacts functionally with the RNA polymerase II complex recruited at the human immunodeficiency virus (HIV) long terminal repeat and plays an important role in HIV gene expression.

CTDP1 PRKDC

3.16e-052196221450944
Pubmed

Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation.

TSC1 MTOR

3.16e-052196215185396
Pubmed

Sorting nexin 10 controls mTOR activation through regulating amino-acid metabolism in colorectal cancer.

SNX10 MTOR

3.16e-052196229867114
Pubmed

Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms.

P4HA2 P4HA1

3.16e-052196229615493
Pubmed

Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis.

PTK2 MTOR

3.16e-052196226295809
Pubmed

BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.

BPTF PRKDC

3.16e-052196228579392
Pubmed

mTORC1 Activation Promotes Spermatogonial Differentiation and Causes Subfertility in Mice.

TSC1 MTOR

3.16e-052196227605345
Pubmed

Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration.

PLD2 MTOR

3.16e-052196227280401
Pubmed

Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling.

TSC1 MTOR

3.16e-052196221268018
Pubmed

Critical roles for the TSC-mTOR pathway in β-cell function.

TSC1 MTOR

3.16e-052196219690069
InteractionINTS6 interactions

ABTB2 MOV10 INTS6L PPP2R1A PPP2R1B INTS6 CTDP1 LRP1

8.99e-061101888int:INTS6
InteractionSNCA interactions

CMBL MYH10 PRPF6 LCMT2 SGSM3 ILVBL DYNC1H1 RANBP1 MYBBP1A NEDD4L ESYT1 PCLO INPP5F ECPAS SKP1 YES1 PPP2R1A PPP2R1B ADAP2 PPP6R3

1.28e-0571618820int:SNCA
InteractionHDAC1 interactions

MYH10 USP11 KIF4A USP19 OVOL2 XYLT2 BPTF SYNJ1 CIITA MKI67 UHRF2 DNMT3L SFMBT1 MYBBP1A TBC1D15 NSD2 CHAF1A RCN2 INPP5F MORC4 ECPAS PPP2R1A PPP2R1B SEC23IP PPP6R3 PCNT

1.36e-05110818826int:HDAC1
InteractionMST1R interactions

KIF4A FBXO6 MKI67 DYNC1H1 RANBP1 DNAH10 PCLO YES1 PRPF40A PRKDC

1.91e-0520018810int:MST1R
InteractionAURKB interactions

XIRP1 MYH10 ABR DNAJC10 AGL MKI67 ILVBL DYNC1H1 MOV10 MYBBP1A RCN2 RNF213 PRC1 SKP1 PPP2R1A TRAP1 CTDP1 MYOM2 PRKDC PPP6R3

3.06e-0576118820int:AURKB
InteractionCIT interactions

MYH10 SPTB EMILIN2 PRPF6 BPTF SAFB DNAJC10 TCERG1 MKI67 UHRF2 DYNC1H1 WWC1 RANBP1 MYBBP1A CHAF1A PCLO RCN2 RNF213 PRC1 ECPAS PRPF40A PPP2R1A TRAP1 DNAH12 P4HA1 CTDP1 MEPCE MYOM2 EIF3B PRKDC

3.13e-05145018830int:CIT
InteractionDIAPH1 interactions

PTK2 TCERG1 GAS7 YES1 PRPF40A MTOR CTDP1 LRP1 PRKDC

4.21e-051761889int:DIAPH1
InteractionFLT1 interactions

PTK2 ILVBL DYNC1H1 DOP1B RNF213 YES1 TRAP1 P4HA1 PRKDC

4.80e-051791889int:FLT1
InteractionNPTN interactions

USP11 TSC1 FCSK FBXO6 SGSM3 HEATR5B DOP1B RNF213 ECPAS P4HA1 MTOR

6.32e-0527818811int:NPTN
InteractionSTIP1 interactions

MYH10 IFT172 PRPF6 GTF3C5 PTK2 USP19 ESYT2 DNAJC10 TCERG1 DYNC1H1 MYBBP1A TBC1D15 ESYT1 RCN2 ECPAS YES1 PPP2R1A TRAP1 MTOR SEC23IP EIF3B PRKDC PPP6R3

6.64e-05100618823int:STIP1
InteractionMORC4 interactions

MOV10 MORC4 PRC1 SKP1 FEV PAX9

6.66e-05741886int:MORC4
InteractionCTNNB1 interactions

MYH10 USP11 TSC1 PRPF6 PTK2 OVOL2 TCERG1 MKI67 UHRF2 DYNC1H1 MOV10 RANBP1 MYBBP1A NEDD4L NSD2 PKP4 PRC1 SKP1 PPP2R1A ARVCF P4HA1 PRKDC CDH7

6.94e-05100918823int:CTNNB1
Cytoband7q22.1

SPDYE2B SPDYE3 SPDYE2 MEPCE SPDYE6

1.33e-0411319757q22.1
Cytoband5q31

TCERG1 SLC4A9 P4HA2 PCDHB7 SKP1

1.45e-0411519755q31
Cytoband21q22.2

ETS2 SYNJ1 DOP1B

3.86e-0433197321q22.2
CytobandEnsembl 112 genes in cytogenetic band chr7q22

SPDYE2B ZAN SPDYE3 SPDYE2 MEPCE SPDYE6

3.88e-042191976chr7q22
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE5 SPDYE2B SPDYE3 SPDYE2 SPDYE6

1.35e-08121305756
GeneFamilyETS transcription factor family

ETS2 ETV3 ETV5 ETV3L FEV

1.53e-06281305534
GeneFamilyDyneins, axonemal

DNAH6 DNAH10 DNAH12 DNAH17

5.65e-06171304536
GeneFamilyProtein phosphatase 2 scaffold subunits|STRIPAK complex

PPP2R1A PPP2R1B

5.13e-05213021266
GeneFamilyExtended synaptotagmins

ESYT2 ESYT1

1.53e-0431302827
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ABR PREX2 TIAM1 SPATA13

1.30e-03661304722
GeneFamilyPhosphoinositide phosphatases

SYNJ1 INPP5F INPP5J

1.55e-033213031079
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ABR NEDD4L PCLO

2.18e-03361303823
GeneFamilyAnoctamins

ANO2 ANO7

2.22e-03101302865
GeneFamilyTudor domain containing

TDRD15 UHRF2 ALG13

2.36e-03371303780
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ABR SPTB TIAM1 SKAP1 SPATA13 ADAP2

3.77e-032061306682
GeneFamilyLow density lipoprotein receptors

LRP1B LRP1

3.80e-03131302634
GeneFamilyAnaphase promoting complex |Tetratricopeptide repeat domain containing

ANAPC16 ANAPC13

4.41e-03141302402
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

TRAF3 PCLO

5.07e-0315130226
GeneFamilyIntegrator complex

INTS6L INTS6

5.07e-031513021366
CoexpressionCAIRO_HEPATOBLASTOMA_CLASSES_UP

KIF4A PRPF6 ENOPH1 PTK2 DNAJC10 TCERG1 MKI67 DOP1B RANBP1 MYBBP1A NSD2 CHAF1A PRC1 ECPAS TRAP1 SEC23IP EIF3B PRKDC

7.72e-0761219418M4772
CoexpressionGSE13762_CTRL_VS_125_VITAMIND_DAY5_DC_UP

ADGRB3 FNDC11 CCDC97 OMP ETV3L LOXHD1 ARVCF CTDP1

8.17e-061361948M1894
CoexpressionHALLMARK_MITOTIC_SPINDLE

MYH10 ABR KIF4A TSC1 DYNC1H1 PRC1 KATNA1 TIAM1 PCNT

1.86e-051991949M5893
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN

SERPINA3 FAM221B FBXO6 SYNJ1 ABTB2 ZAN ESYT1 IFI44 RNF213

1.93e-052001949M9341
CoexpressionGSE17721_LPS_VS_CPG_6H_BMDC_UP

IFT172 SNX10 MOV10 RANBP1 PKP4 FNBP4 GAS7 TBC1D13 CLMP

1.93e-052001949M3998
CoexpressionDAIRKEE_CANCER_PRONE_RESPONSE_BPA

TSC1 RANBP1 TRAP1 MTOR EIF3B

3.76e-05511945M8655
CoexpressionDIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_UP

DUSP12 MAN2A2 USP11 CYP51A1 ETS2 ENOPH1 PIGC TCERG1 AGL TBXAS1 RANBP1 PKP4 KATNA1 SKP1 YES1 PPP2R1A PPP2R1B INTS6 P4HA1 FARS2 SEC23IP ALDH4A1 EIF3B PRKDC PCK2

4.15e-05139919425M535
CoexpressionKANG_DOXORUBICIN_RESISTANCE_UP

KIF4A MKI67 DSCC1 NSD2 PRC1

4.97e-05541945M1037
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

TRAF3IP2 SERPINA3 ETV3 SNX10 ABTB2 FNBP4 KATNA1 WDR59 TBC1D13 TIAM1 SPATA13 ADAP2

7.15e-0541819412M12676
CoexpressionGSE7219_WT_VS_NIK_NFKB2_KO_DC_UP

ABR CYP51A1 ETS2 TLR7 IFI44 RNF213 ST3GAL3 PPP2R1A

7.45e-051851948M377
CoexpressionODONNELL_TFRC_TARGETS_DN

KIF4A BPTF MKI67 RANBP1 NSD2 CHAF1A PRC1

8.18e-051391947M6451
CoexpressionONKEN_UVEAL_MELANOMA_UP

TRAF3 MAN2A2 ABR CYP51A1 ETS2 PTK2 STAT6 TBC1D16 DNAJC10 TCERG1 ABTB2 P4HA2 FNBP4 P4HA1 LRP1 PRKDC ALG13

8.73e-0579019417M12490
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

TRAF3IP2 SERPINA3 ETV3 SNX10 ABTB2 FNBP4 KATNA1 WDR59 TBC1D13 TIAM1 SPATA13 ADAP2

1.04e-0443519412MM1221
CoexpressionGSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP

SOX3 CIITA PRC1 KATNA1 MYOM2 EIF3B INPP5J ALG13

1.19e-041981948M5015
CoexpressionGSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN

ABR BPTF DNAJC10 RANBP1 INTS6 EIF3B PRKDC PCNT

1.24e-041991948M3197
CoexpressionGSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP

MAN2A2 PTK2 GVINP1 INPP5F PRPF40A TIAM1 SKAP1 MYOM2

1.28e-042001948M8030
CoexpressionGSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP

DUSP12 TLR7 SPRYD4 MOV10 NEDD4L GRIA3 MYOM2 PPP6R3

1.28e-042001948M3608
CoexpressionGSE30083_SP1_VS_SP2_THYMOCYTE_DN

RGMB SPTB CMPK2 PXYLP1 ESYT1 PKP4 IFI44 PCK2

1.28e-042001948M5024
CoexpressionGSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_UP

TSC1 USP19 LIAT1 AGL PKP4 IFI44 SKP1 FARS2

1.28e-042001948M9293
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 ABTB2 WWC1 EPS8L2 NEDD4L NRCAM PCLO PKP4 SKAP1 ATP6V0A4

1.53e-081941951093c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 ABTB2 WWC1 EPS8L2 NEDD4L NRCAM PCLO PKP4 SKAP1 ATP6V0A4

1.69e-0819619510eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF4A SNX10 MKI67 DSCC1 CHAF1A PRC1 KATNA1 MEPCE APOL4

6.81e-081711959e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF4A SNX10 MKI67 DSCC1 CHAF1A PRC1 KATNA1 MEPCE APOL4

6.81e-08171195952fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF4A ANKLE1 MKI67 DSCC1 NSD2 CHAF1A PRC1 YES1 WDR59

7.16e-0817219592b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B PKHD1 ANO2 ZAN NRCAM DNAH10 PCLO LOXHD1 MYOM2

1.28e-0718419592cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B PKHD1 ANO2 ZAN NRCAM DNAH10 PCLO LOXHD1 MYOM2

1.28e-0718419592b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B PKHD1 ANO2 ZAN NRCAM DNAH10 PCLO LOXHD1 MYOM2

1.28e-071841959ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR EMILIN2 ETV5 TLR7 CIITA TBXAS1 GAS7 LRP1 ADAP2

1.68e-071901959788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCellBronchial-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABR EMILIN2 CIITA SNX10 TBXAS1 GAS7 TIAM1 LRP1 ADAP2

2.59e-0720019592f5b71e55c2de0e77fdae6667eb57f333acc6cd1
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF4A MKI67 DSCC1 NSD2 CHAF1A PKP4 PRC1 DNAH12

1.28e-061791958e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MKI67 DNAH10 NSD2 CHAF1A PRC1 ECPAS PPP2R1B PCNT

1.57e-061841958081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MKI67 DNAH10 NSD2 CHAF1A PRC1 ECPAS PPP2R1B PCNT

1.57e-06184195884c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MKI67 DNAH10 NSD2 CHAF1A PRC1 ECPAS PPP2R1B PCNT

1.57e-061841958d31d4116d1d196633784863781fa45673607a421
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MKI67 DNAH10 NSD2 CHAF1A PRC1 ECPAS PPP2R1B PCNT

1.57e-061841958a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

MKI67 DNAH10 NSD2 CHAF1A PRC1 ECPAS PPP2R1B PCNT

1.57e-06184195845f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF4A ANKLE1 MKI67 PXYLP1 DSCC1 NSD2 CHAF1A PRC1

1.64e-06185195847c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ETS2 CMPK2 SNX10 PKHD1 IFI44 GAS7 APOL3 LRP1

2.00e-061901958e1c02fe6fa43a36381cb9f02569fa9b1c5f5efdc
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ETS2 CMPK2 SNX10 PKHD1 IFI44 GAS7 APOL3 LRP1

2.00e-0619019586de15ec88426fbf52acb0a8371f82cf03b6a6237
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR EMILIN2 ETV5 TLR7 CIITA TBXAS1 GAS7 ADAP2

2.08e-061911958baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B PKHD1 PXYLP1 ABTB2 NRCAM ZSWIM6 SKAP1 ATP6V0A4

2.08e-0619119583e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

ABR EMILIN2 CIITA SNX10 TBXAS1 TIAM1 LRP1 ADAP2

2.08e-0619119589c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ETS2 CMPK2 SNX10 PKHD1 IFI44 GAS7 APOL3 LRP1

2.08e-06191195881f77bf497b8e0ae0affe7d5f4f00446547229f6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 LRP1B PKHD1 PXYLP1 ABTB2 NRCAM SKAP1 ATP6V0A4

2.33e-06194195804bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 LRP1B PKHD1 PXYLP1 ABTB2 NRCAM SKAP1 ATP6V0A4

2.33e-06194195869bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B SNX10 SORCS2 PKHD1 ABTB2 WWC1 DOP1B NRCAM

2.33e-06194195846070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B SNX10 SORCS2 PKHD1 ABTB2 WWC1 DOP1B NRCAM

2.33e-061941958abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic_early|bone_marrow / Manually curated celltypes from each tissue

CMBL MYH10 SPTB ANKLE1 RANBP1 PRC1 TRAP1 APOL4

2.52e-061961958507254c4c00e535fe01851431b5b74a5f15d9592
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ADGRB3 ETS2 HSPA12B CIITA ANO2 PREX2 APOL3

2.61e-061971958cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ADGRB3 ETS2 HSPA12B CIITA ANO2 PREX2 APOL3

2.61e-061971958412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellAdult-Immune|Adult / Lineage, Cell type, age group and donor

ABR EMILIN2 CIITA SNX10 TBXAS1 TIAM1 LRP1 ADAP2

2.71e-0619819589bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-early_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CMBL MYH10 SPTB ANKLE1 PAQR9 RANBP1 PRC1 PRKDC

2.71e-0619819588d900a17667a41bdfa683a34275fe4c059f6a8ef
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABR EMILIN2 CIITA SNX10 TBXAS1 TIAM1 LRP1 ADAP2

2.82e-0619919587ee2805fd9143eba11bf6832267b62189683608b
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EMILIN2 FCAR CIITA IFI44 GAS7 ZSWIM6 LRP1 ADAP2

2.92e-062001958934c2efc780318c66d667ca75be0de350361d351
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2J2 WWC1 NRCAM HEATR4 PCLO IYD ATP6V0A4 IGSF9B

2.92e-062001958924eacea513dde8e3bd805a335bc4285647b800d
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

KIF4A MKI67 DSCC1 RANBP1 NSD2 CHAF1A PRC1 PRKDC

2.92e-0620019587e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

KIF4A MKI67 DSCC1 RANBP1 NSD2 CHAF1A PRC1 PRKDC

2.92e-0620019589775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABR EMILIN2 CIITA SNX10 TBXAS1 GAS7 LRP1 ADAP2

2.92e-06200195878d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TLR7 FAM186B SLC4A9 ZAN DNAH12

4.64e-0656195520a2977f41d3ecbc4fbee7ecd6dfb4b7ce0e4bb7
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TLR7 FAM186B SLC4A9 ZAN DNAH12

4.64e-06561955ad76712e6a99072f9c6dab6d746db54f754e14fd
ToppCellfacs-Marrow-B-cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFT172 EMILIN2 HENMT1 NEDD4L NRCAM PRC1 LRP1

1.02e-0517019576e82e41acd1299aa549a32ac036b39754abdf376
ToppCellfacs-Marrow-B-cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFT172 EMILIN2 HENMT1 NEDD4L NRCAM PRC1 LRP1

1.02e-05170195718cd941bf3ca7cc0b6af1317bd2619d283353de0
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RGMB KIF4A OVOL2 SNX10 MKI67 ZAN PRC1

1.06e-051711957845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1|Striatum / BrainAtlas - Mouse McCarroll V32

KIF4A ANKLE1 MKI67 DSCC1 RANBP1 PRC1 PRPF40A

1.28e-051761957a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

KIF4A ANKLE1 MKI67 DSCC1 RANBP1 PRC1 PRPF40A

1.28e-051761957d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANKLE1 MKI67 DSCC1 RANBP1 NSD2 CHAF1A PRC1

1.33e-0517719578a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCell10x5'-GI_large-bowel-Mast|GI_large-bowel / Manually curated celltypes from each tissue

CMBL TTLL9 SPTB EMILIN2 TBXAS1 GXYLT1 ALDH4A1

1.38e-051781957d10ed2543c96e1a2373f847e0b82144771e26d07
ToppCell10x5'-GI_large-bowel-Mast-Mast_cells|GI_large-bowel / Manually curated celltypes from each tissue

CMBL TTLL9 SPTB EMILIN2 TBXAS1 GXYLT1 ALDH4A1

1.38e-0517819578fc5f735afa25ae43c2acb1c710ade6e9e093e3c
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5|Striatum / BrainAtlas - Mouse McCarroll V32

KIF4A ANKLE1 MKI67 DSCC1 RANBP1 PRC1 PRPF40A

1.65e-051831957f20b0d71f857ac35868fd80531050ad8b6091716
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF4A ANKLE1 MKI67 DSCC1 CHAF1A PRC1 ALG13

1.65e-0518319576c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

MKI67 DNAH10 NSD2 PRC1 ECPAS PPP2R1B PCNT

1.71e-051841957c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF4A MKI67 DSCC1 NSD2 CHAF1A PRC1 SKAP1

1.71e-0518419571edefa2a049d7e22d0bdb1ea3d7ef1c8d6ae0fe3
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF4A MKI67 DSCC1 NSD2 CHAF1A PRC1 SKAP1

1.71e-0518419578578c50eaa8ce1cefc0228185c66c8e25f4bfc32
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

MKI67 DNAH10 NSD2 PRC1 ECPAS PPP2R1B PCNT

1.71e-0518419572fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH10 EMILIN2 KIF4A MKI67 PAQR9 CHAF1A PRC1

1.83e-0518619577cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH10 EMILIN2 KIF4A MKI67 PAQR9 CHAF1A PRC1

1.83e-051861957ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

GANC CYP51A1 KIF4A LCMT2 MKI67 GAS7 PRC1

1.89e-0518719573c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B ESYT2 SNX10 PKHD1 ABTB2 CYP27C1 SKAP1

1.89e-05187195777886f99c229610abd28c4c370d2c7d1536c9782
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early|lymph-node_spleen / Manually curated celltypes from each tissue

CMBL MYH10 SPTB KIF4A PAQR9 PRC1 APOL4

1.89e-05187195761d346c9873c2edb3ce224a0c063c54d9a68309e
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1B PKHD1 ABTB2 WWC1 PCLO SKAP1 ATP6V0A4

1.89e-051871957d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B SNX10 PKHD1 ABTB2 CYP27C1 SKAP1 ATP6V0A4

1.89e-051871957f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH10 KIF4A MKI67 DSCC1 PAQR9 CHAF1A PRC1

1.89e-051871957dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1B PKHD1 ABTB2 WWC1 NRCAM SKAP1 ATP6V0A4

1.96e-0518819578f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A9 ABTB2 NEDD4L NRCAM SKAP1 ATP6V0A4 INPP5J

2.03e-051891957a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF4A MKI67 EPS8L2 CHAF1A PCLO PRC1

2.05e-0512719566b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH10 SORCS2 NRCAM GAS7 TIAM1 LRP1 CLMP

2.10e-05190195745df8fee00f8949937863159d7aa042e72748d9b
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

CYP2J2 ETS2 CMPK2 MOV10 IFI44 RNF213 APOL3

2.17e-0519119572da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF4A ANKLE1 MKI67 NSD2 CHAF1A PRC1 SKAP1

2.17e-051911957239300ff76f2c855b2b04d3002461158be90a01b
ToppCellStriatum-Macroglia-POLYDENDROCYTE|Striatum / BrainAtlas - Mouse McCarroll V32

ANKLE1 MKI67 DSCC1 RANBP1 PRC1 PRPF40A ALG13

2.17e-0519119576bc9c7c86040f3ebce08c350e625e345581d4550
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1B PKHD1 ABTB2 WWC1 PKP4 SKAP1 ATP6V0A4

2.17e-051911957fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

ABR EMILIN2 CIITA SNX10 TBXAS1 TIAM1 LRP1

2.17e-051911957dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABR EMILIN2 CIITA SNX10 TBXAS1 TIAM1 LRP1

2.24e-051921957bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 SORCS2 SLC4A9 ABTB2 NEDD4L ATP6V0A4 INPP5J

2.24e-05192195740f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN2 ETV5 TLR7 CIITA TBXAS1 GAS7 ADAP2

2.32e-051931957f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV5 TBC1D16 DNAJC10 SGSM3 GXYLT1 ST3GAL3 ANO7

2.32e-0519319576a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B PKHD1 WWC1 EPS8L2 NEDD4L PCLO ATP6V0A4

2.32e-05193195782e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 ABTB2 WWC1 NEDD4L PCLO PKP4 ATP6V0A4

2.32e-0519319573866667dd221612589ae50f5c52f73a183a49ce6
ToppCellcontrol-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIF4A MKI67 DSCC1 RANBP1 NSD2 CHAF1A PRC1

2.32e-051931957ecb4018a47d9a82bb999e0bc8b3dceabd97d1f0d
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CMPK2 TLR7 ABTB2 MOV10 IFI44 RNF213 APOL3

2.32e-05193195722455801194bd8c73c5c397f5eac4f723429c383
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 ABTB2 WWC1 EPS8L2 NEDD4L PCLO ATP6V0A4

2.40e-0519419575eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYP51A1 KIF4A MKI67 RANBP1 PRC1 IGSF9B SPDYE6

2.40e-051941957ded64ddab86de17fcf8b70d31bc26796eb71d60f
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|World / Lineage, cell class and subclass

MYH10 SPTB KIF4A MKI67 DSCC1 PRC1 APOL4

2.40e-051941957008bb0072f414a48d052429101bdc990ee4f80c2
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ETS2 EMILIN2 CIITA TBXAS1 GAS7 ZSWIM6 ADAP2

2.40e-051941957663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ADGRB3 ETS2 HSPA12B CIITA IFI44 PREX2

2.40e-051941957e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABR TBC1D16 SNX10 DOP1B TBXAS1 LRP1 ADAP2

2.48e-0519519579d649ac7d2af313481069c95349efc0c68449e2b
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

ABR EMILIN2 CIITA SNX10 TBXAS1 LRP1 ADAP2

2.48e-051951957148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellmild-Lymphocytic-Prol._cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF4A MKI67 DSCC1 RANBP1 NSD2 CHAF1A PRC1

2.48e-0519519579a8cc9097a349fd0a53ccf2723ee8bb1418d6aca
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B PKHD1 ABTB2 WWC1 NEDD4L PCLO PKP4

2.48e-0519519576477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

SPTB KIF4A MKI67 NSD2 PRC1 SKAP1 PCNT

2.48e-051951957764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ADGRB3 ETS2 HSPA12B ANO2 PREX2 APOL3

2.56e-0519619578ad8efb631164b46f0c082572270188e5ead20bf
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

PTK2 MKI67 DNAH6 WWC1 NEDD4L YES1 DNAH12

2.56e-0519619576d02d494196e3f857d53eea46d9419690d43beca
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

PTK2 MKI67 DNAH6 WWC1 NEDD4L YES1 DNAH12

2.56e-051961957af4cdc61830685a888a1209826c23bcf54a43084
ToppCellmild-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF4A MKI67 DSCC1 RANBP1 NSD2 CHAF1A PRC1

2.56e-051961957b1d9866d5dfaefdb8bedaf01a750d97987acb3d1
ToppCellCOVID-19-lung-Macrophage_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

ABR EMILIN2 CIITA SNX10 TBXAS1 LRP1 ADAP2

2.56e-051961957a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 WWC1 EPS8L2 NEDD4L PCLO SKAP1 ATP6V0A4

2.56e-0519619576ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ADGRB3 ETS2 HSPA12B ANO2 PREX2 APOL3

2.56e-0519619579606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABR EMILIN2 TLR7 CIITA TBXAS1 GAS7 TIAM1

2.64e-05197195757dafb3047745a44b2345b8036e159c3641d496e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABR EMILIN2 CIITA TBXAS1 GAS7 LRP1 ADAP2

2.64e-0519719578af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABR EMILIN2 CIITA SNX10 TBXAS1 RNF213 ADAP2

2.64e-051971957e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABR EMILIN2 CIITA SNX10 TBXAS1 TIAM1 SKAP1

2.64e-051971957f18807124b91310fcd84238484a80ecdba684679
DiseaseFocal Cortical Dysplasia of Taylor, Type IIb

TSC1 MTOR

1.19e-0431872C1846389
DiseaseFOCAL CORTICAL DYSPLASIA OF TAYLOR

TSC1 MTOR

1.19e-0431872C1846385
DiseaseFocal Cortical Dysplasia of Taylor, Type IIa

TSC1 MTOR

1.19e-0431872C1846386
DiseaseIsolated focal cortical dysplasia type II

TSC1 MTOR

1.19e-0431872cv:C1846385
DiseaseFOCAL CORTICAL DYSPLASIA, TYPE II

TSC1 MTOR

1.19e-0431872607341
Diseasekidney disease (implicated_via_orthology)

KL YES1 APOL3 APOL4

1.32e-04411874DOID:557 (implicated_via_orthology)
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

TSC1 PKHD1 MTOR

1.32e-04161873DOID:0110861 (implicated_via_orthology)
DiseaseIntellectual Disability

PET100 KIF4A FCSK BPTF DYNC1H1 NSD2 ST3GAL3 PPP2R1A MTOR ALDH4A1 ALG13

1.43e-0444718711C3714756
Diseaseinterstitial cystitis (is_marker_for)

MKI67 MTOR

3.95e-0451872DOID:13949 (is_marker_for)
Diseaserenal fibrosis (is_implicated_in)

CYP2J2 FCAR

3.95e-0451872DOID:0050855 (is_implicated_in)
Diseasenasopharyngeal neoplasm

ETV3 HENMT1 CIITA PCLO GAS7 LIG4

4.16e-041511876EFO_0004252
DiseaseX-16570 measurement

UHRF2 FA2H

5.89e-0461872EFO_0800759
DiseaseEpileptic encephalopathy

NEDD4L MTOR ALG13

8.97e-04301873C0543888
Diseaseperceived unattractiveness to mosquitos measurement

STAT6 P4HA2 CLMP CDH7

1.15e-03721874EFO_0008380
Diseasehypertension (implicated_via_orthology)

TRH PTK2 KL TBXAS1 MTOR

1.37e-031281875DOID:10763 (implicated_via_orthology)
DiseaseUnipolar Depression

TRH TLR7 PCLO MTOR LRP1 CDH7 PCNT

1.38e-032591877C0041696
Diseasecomparative body size at age 10, self-reported

TRAF3 ETV5 LRP1B PKHD1 MOV10 ZSWIM6 SPDYE18 APOL3 PPP6R3

1.51e-034201879EFO_0009819
Diseasenephritis (implicated_via_orthology)

CYP2J2 PTK2

1.74e-03101872DOID:10952 (implicated_via_orthology)
DiseaseProstatic Neoplasms

SERPINA3 RGMB ABR ETV3 ETV5 LRP1B DNAJC10 TBXAS1 MYBBP1A LIFR PRKDC

2.01e-0361618711C0033578
DiseaseMalignant neoplasm of prostate

SERPINA3 RGMB ABR ETV3 ETV5 LRP1B DNAJC10 TBXAS1 MYBBP1A LIFR PRKDC

2.01e-0361618711C0376358
Diseaseunipolar depression, age at onset

ETS2 NEDD4L FARS2

2.08e-03401873EFO_0003761, EFO_0004847
Diseasethyroid peroxidase antibody measurement, anti-thyroglobulin antibody measurement

CAPN9 YES1 WDR59

2.92e-03451873EFO_0005666, EFO_0009896
Diseasecerotoylcarnitine (C26) measurement

ST3GAL3 PPP6R3

2.98e-03131872EFO_0800542
DiseaseCakut

LIFR TRAP1

2.98e-03131872C1968949
DiseaseMalformations of Cortical Development

DYNC1H1 MTOR

3.46e-03141872C1955869
DiseaseN-acetylglycine measurement

OVOL2 UHRF2

3.46e-03141872EFO_0021002
Diseaselysophosphatidylcholine 15:0 measurement

LRP1B PKHD1

3.46e-03141872EFO_0020941
DiseaseCortical Dysplasia

DYNC1H1 MTOR

3.46e-03141872C0431380
Diseasepolycystic kidney disease (implicated_via_orthology)

IFT172 XYLT2

3.46e-03141872DOID:0080322 (implicated_via_orthology)
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

PIGC PAQR9 SKAP1

3.73e-03491873EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Diseaseepilepsy (implicated_via_orthology)

KIF4A LRP1B DYNC1H1 NRCAM LRP1

3.90e-031631875DOID:1826 (implicated_via_orthology)
DiseaseDown syndrome (implicated_via_orthology)

SYNJ1 DOP1B

3.97e-03151872DOID:14250 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

TSC1 MTOR

3.97e-03151872C0496930
DiseaseBenign neoplasm of bladder

TSC1 MTOR

3.97e-03151872C0154017
DiseaseCarcinoma in situ of bladder

TSC1 MTOR

3.97e-03151872C0154091
DiseaseMajor Depressive Disorder

TLR7 PCLO MTOR LRP1 CDH7 PCNT

4.67e-032431876C1269683
DiseaseMouth Neoplasms

TSC1 PTK2 TIAM1

4.90e-03541873C0026640
DiseaseMetastatic melanoma

PTK2 MTOR PRKDC

4.90e-03541873C0278883
DiseaseMalignant neoplasm of mouth

TSC1 PTK2 TIAM1

4.90e-03541873C0153381
DiseaseMoyamoya Disease

RNF213 PCNT

5.10e-03171872C0026654
DiseaseColorectal Carcinoma

KL MKI67 PKHD1 UHRF2 NRCAM PREX2 LIFR PPP2R1B TIAM1 LRP1 CDH7

5.36e-0370218711C0009402
Diseasefood allergy measurement, parental genotype effect measurement

IQCE CLMP

5.72e-03181872EFO_0005939, EFO_0007016
Diseaseserum IgG measurement

DUSP12 TRAF3

5.72e-03181872EFO_0004565
DiseaseCarcinoma of bladder

TSC1 MTOR

5.72e-03181872C0699885
Diseasecoffee consumption measurement

SORCS2 PKHD1 ANAPC13 FA2H FARS2

6.19e-031821875EFO_0006781

Protein segments in the cluster

PeptideGeneStartEntry
IQKDPREFAWRDPEL

PKP4

516

Q99569
RVFRDTAEPKWDEEF

ABR

541

Q12979
PAIVELAEDAKWRVR

PPP2R1A

406

P30153
LLPAIVELAEDAKWR

PPP2R1B

416

P30154
IDDREDVWKFAPNLI

CTDP1

301

Q9Y5B0
ERWDKVEEQLFPLRD

CTDP1

716

Q9Y5B0
FEWELPLDEAQRRKL

ESYT1

1041

Q9BSJ8
KERLLDEWFTLDEVP

ESYT2

481

A0FGR8
RWVLFEEKLEVAAGR

SLC4A9

101

Q96Q91
NDVKDPVSIEERARW

EIF3B

321

P55884
RNVEFDVWLDSRKEL

ALG13

466

Q9NP73
PERWLRKGDLDRVDN

CYP27C1

461

Q4G0S4
VEELEADEWRFKPIE

ANAPC16

86

Q96DE5
LRDALREEEPWAVEE

ANKLE1

11

Q8NAG6
VDSARKEPRWRDPEL

ARVCF

346

O00192
DTVRKDVEEWGPFDL

DNMT3L

226

Q9UJW3
RKDWNPAETRDFIDA

CYP2J2

266

P51589
LKRWRDSLEFREIGE

SERPINA3

296

P01011
EAKDALELRPAEWEK

ADGRB3

1491

O60242
AWKRFVRVAELPREE

APOL4

61

Q9BPW4
KSLERELATPDWAER

CIITA

376

P33076
KLTDPDEVARRWGER

FEV

76

Q99581
LKRRWNDDPEARELS

ETV3

476

P41162
RVFLEDVKSWEVSDP

GVINP1

521

Q7Z2Y8
AARKEWDLKPIADRA

ALDH4A1

111

P30038
VDRRFPKKWERPVAE

FAM186B

421

Q8IYM0
RPDAVRTKDIGIWFD

ANO2

791

Q9NQ90
IRARDPWAQDTKLLD

CHAF1A

581

Q13111
WEIRAFAERVEKEKA

BPTF

2021

Q12830
ELLDTFRPDIVVKDW

FBXO6

156

Q9NRD1
FRPDIVVKDWFAARA

FBXO6

161

Q9NRD1
PDISRVKSVRLDFWD

ADAP2

56

Q9NPF8
ANEDPEWILVEKDRF

RCN2

221

Q14257
WPRDQKAGEEDLRFR

RBAKDN

41

A6NC62
FRFASENDLPEWKER

RANBP1

56

P43487
ELTKEPFRWDQRLFA

INTS6L

156

Q5JSJ4
ELTKEPFRWDQRLFA

INTS6

156

Q9UL03
DFVRTLAEKRPDASW

IQCE

196

Q6IPM2
DPTAIFWRKEDSDAI

OMP

101

P47874
KPRIADFVLVWEEDL

ANO7

106

Q6IWH7
KQRDPGIFAWEIRDR

PAX9

91

P55771
PEFKRPRDIAVDWVA

LRP1B

3966

Q9NZR2
ASFAEERRVWLEEKE

LZTS3

596

O60299
VLKPEWFRGRDVLDL

MEPCE

436

Q7L2J0
WLKDNRELPSDERFT

NRCAM

581

Q92823
GEKELPQWLREDERF

WWC1

1026

Q8IX03
DWEEDPKDSRRGRLE

LRP1

666

Q07954
RAWRKEVLELFLDPA

DOP1B

1966

Q9Y3R5
EIEEWERKLLAQAAP

KIAA2026

281

Q5HYC2
VEFPCLRWLDKDKDD

LOXHD1

651

Q8IVV2
VEFWLEKDEFGRRDL

BPIFA3

146

Q9BQP9
WVPDSEERLILREEF

CCDC97

271

Q96F63
KLPEIWETLFRVQDD

ECPAS

1201

Q5VYK3
RWVRLDEREFPEAKN

GRIA3

286

P42263
IGRRLKFWNETDPEF

FCAR

71

P24071
ETDWFDKPRESRLEN

PCLO

4441

Q9Y6V0
FSLPKDFWEQEVRDI

PCK2

596

Q16822
FKLADPDEVARRWGK

ETS2

391

P15036
RPEEVGEFWLKRRAT

FAM221B

306

A6H8Z2
ESSEAVPEKTWREFR

FAM74A3

46

Q4VXF1
PERAWIFEKSLVAFE

NSD2

271

O96028
KQLDPERKLEDAWAR

FAM47B

151

Q8NA70
RPLWVEFPDELKTFD

GANC

696

Q8TET4
VDTDILFLRPVDDIW

GXYLT1

216

Q4G148
IKPFEHEIKAWEDRL

DNAH12

881

Q6ZR08
REFALSETPDRKWVV

DNAH12

1601

Q6ZR08
FKLIEPEEVARRWGI

ETV5

396

P41161
WPKRSLRKADVEEEF

MKI67

1146

P46013
VRSWDELPDEKRADT

OVOL2

16

Q9BRP0
PAAWVDLTIAFEARK

HSPA12B

381

Q96MM6
LEREREKPAWLQAEL

PCNT

2861

O95613
DEVRAWLEAKAFSPR

EPS8L2

631

Q9H6S3
LDFFWDIAKPEQETR

MYBBP1A

36

Q9BQG0
AKPLLRWDEVPDDFV

PAQR9

41

Q6ZVX9
ESSEAVPEKTWREFR

FAM74A7

46

A6NL05
RLAFPVEVVKLEEAW

IFT172

846

Q9UG01
WLEEDDDPVVARVNR

P4HA2

386

O15460
VWEDIRERFVKEPAF

PRPF40A

766

O75400
AKQEDEWDKPRIIRF

P4HA1

326

P13674
EPRFKVVDWDKDLVD

FA2H

111

Q7L5A8
EKPFQIFRAELWVRD

PCDHB7

111

Q9Y5E2
DPRLQDLKAREAEAW

RBBP8NL

316

Q8NC74
EALAQERDKWLSRPA

FCSK

651

Q8N0W3
FFADVVPAVRKWREA

ENOPH1

131

Q9UHY7
ILDLIDDAWREDKLP

ANAPC13

11

Q9BS18
WRKIFDDEPTIIRRA

CMPK2

291

Q5EBM0
DFDTKRLDPWERIIP

DNAH6

2041

Q9C0G6
EDKLRWRGDSLAPFL

HENMT1

81

Q5T8I9
WRNVFPRSLKELEAE

HEATR5B

581

Q9P2D3
RRMLWAADDFLEDLP

IFI44

411

Q8TCB0
PDWVEELREADRQKE

ILVBL

416

A1L0T0
LFSLREKWTEEDIAP

DSCC1

341

Q9BVC3
LRFPRIEKIRDDKEW

LIG4

576

P49917
RFLEETEGIPWEVKA

DNAH17

2971

Q9UFH2
PFLADWALVERRLAD

FNDC11

151

Q9BVV2
PPVWEARKLSRDEDD

FRS2

356

Q8WU20
ERFRLDAWKRAEAIE

CENPJ

1046

Q9HC77
RLKDSWVERLDFNPD

CYP51A1

416

Q16850
EEREAWLLPPEKEAR

HEATR4

186

Q86WZ0
WKRFVTAAELPRDEA

APOL3

106

O95236
SKLQEDPRRRFLWAE

MAN2A2

201

P49641
RREEFVQWVELLPDT

DYNC1H1

4301

Q14204
LLDAESEDRPKQRWE

KIF4A

841

O95239
KEVAERVLEFDIGWL

KL

746

Q9UEF7
FPWDIDEALRRRLEK

KATNA1

361

O75449
RLIVPEPDVDFDAKW

EMILIN2

436

Q9BXX0
IFREFIWERLKEADV

CDH7

706

Q9ULB5
PTWRDFAKEVDGLLR

DNAJC10

166

Q8IXB1
GEFVIKDPDEVARLW

ETV3L

66

Q6ZN32
WLDVVIDDRLPTFRD

CAPN9

141

O14815
EFRKILRAEGRVEDW

DNAH10

1626

Q8IVF4
GVEDLWRLFVPALDK

DUSP12

71

Q9UNI6
RDGRPLWQKVDDRFF

INPP5F

196

Q9Y2H2
SDRFVAELWKDVDRI

MYH10

611

P35580
LVKWEDIPVEELRGF

LIFR

741

P42702
TRAEARPWVDEDLKD

IYD

36

Q6PHW0
EFEVKRALEWLGADR

MTOR

146

P42345
PEESRKLRFWNLEFE

PUSL1

211

Q8N0Z8
ALEDVEALHPRKERW

RGMB

391

Q6NW40
DWKLLTDAEKRPFID

SOX3

176

P41225
KRLPTEEEWEFAARG

SUMF2

161

Q8NBJ7
VELKPHDVRLCEEFW

PRLHR

201

P49683
PTKVALNVERFREWA

SPRYD4

61

Q8WW59
RRRKWPFDRSAEDLD

SYNJ1

811

O43426
RDVDIPAEISSWFKD

TDRD15

1086

B5MCY1
NFEALPEDWRARLKR

FNBP4

996

Q8N3X1
RWDGILADPEAEKER

LIAT1

171

Q6ZQX7
FFRLDRWADVRFPEK

MOV10

76

Q9HCE1
LWKAAVELEEPEDAR

PRPF6

406

O94906
EDQRWLEKEERFLKP

PTK2

821

Q05397
VDPAKDRELWVREHK

GAS7

451

O60861
EELAERRKAVESWNP

MORC4

716

Q8TE76
TWRLFLEFERKASDP

PRC1

361

O43663
RSDWELVKVDFRPSF

SORCS2

631

Q96PQ0
RGWFPAKFVEVLDER

SGSM3

526

Q96HU1
TRDIKAEELFLWVPR

SETD3

111

Q86TU7
DDSFRKWARIREFVP

ST3GAL3

111

Q11203
ARLIFELWQDREKPS

PXYLP1

401

Q8TE99
RIIVEDAVDWRPHDK

PKHD1

2881

P08F94
RIRKAAYWEEEPAEV

SEC23IP

326

Q9Y6Y8
GPWDEAEIKEDLSRF

PIGC

281

Q92535
RLLEDPVIKRFLAWD

SPDYE2B

201

A6NHP3
LDRRDDAYWPEAKRA

SAFB

716

Q15424
EFPWTEGDVARVLRK

ABTB2

96

Q8N961
GFVDRPQWSEEREEK

ANHX

231

E9PGG2
WQRIREKEGEDERLP

CLMP

166

Q9H6B4
DKPYIDEARRNLIEW

CMBL

226

Q96DG6
DIFEDRIRGIDIIKW

TRAF3IP2

441

O43734
IREWANKNFREEEPR

CNGA2

76

Q16280
VRLEVADEWVRPEQA

INPP5J

741

Q15735
DKEAWFPASFVRLRV

SPATA13

191

Q96N96
EELRERVWALFDVRP

UHRF2

26

Q96PU4
EEDLAPFSLRKRWES

RNF213

2286

Q63HN8
KREFPFPDVLRLWEV

TBC1D17

501

Q9HA65
ADSVLFLRDKRWEEV

TBXAS1

121

P24557
FDIAVKWRRIADPDQ

TTC13

566

Q8NBP0
KELDKEIRPFRQNWE

TRAF3

331

Q13114
IWRDKINDLVEFPVR

USP19

1116

O94966
ELDPRRWKRLETHDV

TSC1

241

Q92574
EEVIWVRREDFAPSR

TIAM1

1571

Q13009
WDRPDDLIGRADVDK

TCERG1

556

O14776
FRVAERWELLDDGIP

IGSF9B

651

Q9UPX0
RLLEDPVIKRFLAWD

SPDYE16

161

A6NNV3
RLLEDPVIKRFLAWD

SPDYE18

201

P0DV79
RLLEDPVIKRFLAWD

SPDYE21

201

A0A494C086
RLLEDPVIKRFLAWD

SPDYE2

201

Q495Y8
EDPVIKRFLAWDKDL

SPDYE3

401

A6NKU9
RLLEDPVIKRFLAWD

SPDYE5

201

A6NIY4
RLLEDPVIKRFLAWD

SPDYE6

201

P0CI01
DRVPFVVAERVPWEK

STAT6

436

P42226
KREFPEAEALRIWEA

TBC1D16

616

Q8TBP0
RTDDIPVWDQEFLKV

SKP1

81

P63208
LPDVIRIWDSLFADD

TBC1D13

331

Q9NVG8
PEEKHEWFEAILKER

PREX2

346

Q70Z35
WAERFAALEKPTTLE

SPTB

2061

P11277
LEKDAEVIVDWRPLD

TBC1D15

41

Q8TC07
EWVLAELVAKLEDPR

TLR7

906

Q9NYK1
VSVWVRDPRIQKEDF

SNX10

11

Q9Y5X0
WDREKRLSFAVPFRE

PRKDC

886

P78527
RVISDLDWAVFEPDL

WDR59

106

Q6PJI9
WFPVADATRIKRALE

ATP6V0A4

326

Q9HBG4
DVLRHRPGWVEVKDE

TTLL9

56

Q3SXZ7
AEKWPFQRVEERFER

ZSWIM6

86

Q9HCJ5
PKWLRFIRGVVDSED

TRAP1

381

Q12931
RRLADPKAQRSWEEE

TRH

156

P20396
EGIRDKVSDWDEFLR

SFMBT1

121

Q9UHJ3
RLLEDPVIKRFLAWD

nan

161

A6NJR5
EEELRKLFDIRPIWS

GTF3C5

251

Q9Y5Q8
WEVDFPDVARRKAER

LCMT2

111

O60294
IPDIRLFWCEDERFL

FARS2

326

O95363
GDPKWLDVIERDLHR

TBC1D10A

146

Q9BXI6
KDLPDEVRERWETFC

PPP6R3

486

Q5H9R7
TKDWVQLDRPFEDFI

PLD2

516

O14939
RFLVEPQEDTRLWAK

USP11

231

P51784
GDVRAARWLFETKPL

XIRP1

151

Q702N8
LPEEIRWLLEDAEEF

SKAP1

6

Q86WV1
LEVGTDWDPKERLFR

XYLT2

646

Q9H1B5
DKCVPDRDPRWEVLD

THEG

311

Q9P2T0
AKDAWEIPRESLRLE

YES1

266

P07947
SWEVKTEDALLRFPR

ZAN

2496

Q9Y493
EDDVIQRKRELWPPE

PET100

31

P0DJ07
KFRSLDWENPTERED

AGL

61

P35573
QPRAEWYRDDVLLKE

MYOM2

311

P54296
PDVLKARLWIEFESE

NEDD4L

641

Q96PU5