Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC18 ZDHHC9 ZDHHC14	1.68e-04	26	83	3	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC18 ZDHHC9 ZDHHC14	1.68e-04	26	83	3	GO:0019707
GeneOntologyMolecularFunction	hypotaurine monooxygenase activity	FMO3 FMO5	1.69e-04	5	83	2	GO:0047822
GeneOntologyMolecularFunction	N,N-dimethylaniline monooxygenase activity	FMO3 FMO5	2.53e-04	6	83	2	GO:0004499
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC18 ZDHHC9 ZDHHC14	2.59e-04	30	83	3	GO:0016417
GeneOntologyMolecularFunction	palmitoyltransferase activity	ZDHHC18 ZDHHC9 ZDHHC14	4.86e-04	37	83	3	GO:0016409
Domain	zf-DHHC	ZDHHC18 ZDHHC9 ZDHHC14	1.31e-04	23	81	3	PF01529
Domain	WD40	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	1.32e-04	259	81	7	PF00400
Domain	WD40	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	1.63e-04	268	81	7	SM00320
Domain	DHHC	ZDHHC18 ZDHHC9 ZDHHC14	1.69e-04	25	81	3	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC18 ZDHHC9 ZDHHC14	1.69e-04	25	81	3	IPR001594
Domain	WD40_repeat	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	1.78e-04	272	81	7	IPR001680
Domain	FMO-like	FMO3 FMO5	1.84e-04	5	81	2	PF00743
Domain	Flavin_mOase	FMO3 FMO5	1.84e-04	5	81	2	IPR000960
Domain	Flavin_mOase-like	FMO3 FMO5	1.84e-04	5	81	2	IPR020946
Domain	DiMe-aniline_mOase	FMO3 FMO5	1.84e-04	5	81	2	IPR012143
Domain	WD_REPEATS_1	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	2.04e-04	278	81	7	PS00678
Domain	WD_REPEATS_2	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	2.09e-04	279	81	7	PS50082
Domain	WD_REPEATS_REGION	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	2.09e-04	279	81	7	PS50294
Domain	WD40_repeat_dom	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	3.05e-04	297	81	7	IPR017986
Domain	-	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	6.04e-04	333	81	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	DNAI1 ZNF106 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	6.26e-04	335	81	7	IPR015943
Domain	SANT	ZSCAN20 SMARCC1 SNAPC4	1.33e-03	50	81	3	SM00717
Domain	SANT/Myb	ZSCAN20 SMARCC1 SNAPC4	1.49e-03	52	81	3	IPR001005
Domain	N2O_reductase_N	SNRNP40 WDR1	1.88e-03	15	81	2	IPR011045
Domain	DSRM	STRBP STAU2	3.03e-03	19	81	2	SM00358
Domain	RCC1	MYCBP2 HERC1	3.36e-03	20	81	2	PF00415
Domain	dsrm	STRBP STAU2	3.36e-03	20	81	2	PF00035
Domain	RCC1_1	MYCBP2 HERC1	3.70e-03	21	81	2	PS00625
Domain	RCC1_2	MYCBP2 HERC1	3.70e-03	21	81	2	PS00626
Domain	DS_RBD	STRBP STAU2	3.70e-03	21	81	2	PS50137
Domain	RCC1_3	MYCBP2 HERC1	3.70e-03	21	81	2	PS50012
Domain	Reg_chr_condens	MYCBP2 HERC1	4.06e-03	22	81	2	IPR000408
Domain	-	MYCBP2 HERC1	4.06e-03	22	81	2	2.130.10.30
Domain	RCC1/BLIP-II	MYCBP2 HERC1	4.43e-03	23	81	2	IPR009091
Domain	WD40_repeat_CS	CDC20B SNRNP40 WDR1 HERC1	5.64e-03	164	81	4	IPR019775
Domain	-	STRBP STAU2	6.08e-03	27	81	2	3.30.160.20
Domain	dsRBD_dom	STRBP STAU2	6.53e-03	28	81	2	IPR014720
Pubmed	S-Palmitoylation of a Novel Site in the β2-Adrenergic Receptor Associated with a Novel Intracellular Itinerary.	ZDHHC18 ZDHHC9 ZDHHC14	1.35e-07	5	84	3	27481942
Pubmed	Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation.	ZDHHC18 ZDHHC9 ZDHHC14	2.70e-07	6	84	3	38182928
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LIG1 SCAF1 ZNF106 LIMA1 WAPL MYCBP2 ANAPC1 ZNF335 SMARCC1 PRPF38B TNKS1BP1 SNAPC4	3.54e-07	774	84	12	15302935
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NEK1 ZFYVE16 MYCBP2 ANAPC1 BCORL1 DOCK7 TNKS1BP1 TASOR MSTO1	7.98e-07	418	84	9	34709266
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	WAPL CTTNBP2 MYCBP2 ANAPC1 TNKS1BP1 CRYZL1 TASOR	8.62e-07	212	84	7	33853758
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	LIMA1 WAPL ANAPC1 WBP4 STAU2 SNRNP40 SMARCC1 WDR1 IMMT TBCD	1.03e-06	560	84	10	35241646
Pubmed	The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.	WAPL ANAPC1 SNRNP40 RPA1 TASOR	1.94e-06	84	84	5	26299517
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NEK1 LIMA1 WAPL ZFYVE16 SH3D19 STAU2 PRPF38B TNKS1BP1 WDR1 RPA1 TASOR AKAP12	2.51e-06	934	84	12	33916271
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	NEK1 LIMA1 YJU2 ZFYVE16 MYCBP2 STRBP SH3D19 WBP4 STAU2 SNRNP40 PPAT AKAP12	5.41e-06	1007	84	12	34597346
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NEK1 LIMA1 WAPL MYCBP2 ANAPC1 SH3D19 DOCK7 SMARCC1 TNKS1BP1	7.34e-06	549	84	9	38280479
Pubmed	Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.	ZDHHC18 ZDHHC9 ZDHHC14	7.44e-06	16	84	3	23034182
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	LIMA1 ZSCAN20 GYS1 SMARCC1 WDR1 CMYA5 RPA1 IMMT	1.38e-05	451	84	8	36168627
Pubmed	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.	ZDHHC18 ZDHHC9 ZDHHC14	1.50e-05	20	84	3	16647879
Pubmed	Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.	FMO3 FMO5	1.73e-05	3	84	2	11551524
Pubmed	Gender differences in hepatic expression of flavin-containing monooxygenase isoforms (FMO1, FMO3, and FMO5) in mice.	FMO3 FMO5	1.73e-05	3	84	2	7473608
Pubmed	Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse.	NEK1 WAPL	1.73e-05	3	84	2	27760328
Pubmed	Functional activity of the mouse flavin-containing monooxygenase forms 1, 3, and 5.	FMO3 FMO5	1.73e-05	3	84	2	17721934
Pubmed	Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny.	FMO3 FMO5	1.73e-05	3	84	2	26839369
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	LIMA1 CTTNBP2 MYCBP2 ANAPC1 SH3D19 DOCK7 SMARCC1 SPATS2 WDR1 RPA1 AKAP12	2.04e-05	963	84	11	28671696
Pubmed	DDX39B drives colorectal cancer progression by promoting the stability and nuclear translocation of PKM2.	LIMA1 ZNF185 WDR1 IMMT	3.04e-05	73	84	4	35973989
Pubmed	Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells.	LRP4 DDX4	3.45e-05	4	84	2	16434236
Pubmed	Quantitative analysis of FMO gene mRNA levels in human tissues.	FMO3 FMO5	3.45e-05	4	84	2	16183778
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	WAPL NDUFAF1 STRBP DOCK7 IMMT MSTO1 SLC27A4 TBCD	3.56e-05	515	84	8	31617661
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ZNF106 NEK1 LIMA1 MYCBP2 SH3D19 MAP3K20 DOCK7 MAP3K9 TNKS1BP1 DOP1A	4.34e-05	861	84	10	36931259
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	ZDHHC18 LIMA1 NDUFAF1 SH3D19 SPATS2 AGAP7P PPAT FAF1	4.72e-05	536	84	8	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	ZDHHC18 LIMA1 NDUFAF1 SH3D19 SPATS2 AGAP7P PPAT FAF1	4.84e-05	538	84	8	10512203
Pubmed	The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression.	FMO3 FMO5	5.74e-05	5	84	2	8128486
Pubmed	Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine.	FMO3 FMO5	5.74e-05	5	84	2	32156684
Pubmed	A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.	FMO3 FMO5	5.74e-05	5	84	2	8311461
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	ZNF106 LIMA1 MAN2B1 PXDN ZFYVE16 MYCBP2 STRBP GYS1 PRPF38B TNKS1BP1 RPA1 AKAP12	6.51e-05	1297	84	12	33545068
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ZNF106 WAPL ZFYVE16 MYCBP2 ANAPC1 WBP4 TASOR ITPRIPL1 SLC27A4	7.03e-05	733	84	9	34672954
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	NEK1 LIMA1 MYCBP2 DNAAF10 GYS1 DOCK7 PCARE TNKS1BP1 RPA1 IMMT AKAP12 TBCD	7.75e-05	1321	84	12	27173435
Pubmed	Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.	LIMA1 NDUFAF1 PPAT	8.41e-05	35	84	3	28106071
Pubmed	Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.	FMO3 FMO5	8.59e-05	6	84	2	12527699
Pubmed	Association of gene polymorphisms with chronic kidney disease in Japanese individuals.	PXDN AKAP12 TBCD	1.17e-04	39	84	3	19724895
Pubmed	An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry.	ZNF106 LIMA1 ZNF185	1.56e-04	43	84	3	30975701
Pubmed	XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia.	LIG1 RPA1	1.60e-04	8	84	2	20575039
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	LIG1 MAN2B1 DNAAF10 TNKS1BP1 WDR1 HERC1 CMYA5 PPAT RPA1 FAF1 AKAP12 TBCD	1.91e-04	1455	84	12	22863883
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PXDN MYCBP2 SH3BP2 ZDHHC14 SCP2 TMPRSS2 PRPF38B SPATS2 FAF1 TBCD DOP1A FAM149A	2.37e-04	1489	84	12	28611215
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	NDUFAF1 MYCBP2 DNAAF10 SH3D19 STAU2 SCP2 SPATS2 HERC1 PPAT RPA1 IMMT DDX4	2.47e-04	1496	84	12	32877691
Pubmed	Polymorphism discovery in 62 DNA repair genes and haplotype associations with risks for lung and head and neck cancers.	LIG1 RPA1	2.56e-04	10	84	2	17494052
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	LIMA1 ZNF335 SMARCC1 PCARE HERC1	2.65e-04	234	84	5	36243803
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	LIG1 STRBP GYS1 STAU2 SMARCC1 WDR1 RPA1 MSTO1	3.05e-04	704	84	8	29955894
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	ZNF106 MYCBP2 ANAPC1 BCORL1 TASOR	3.09e-04	242	84	5	34011540
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	NEK1 MYCBP2 SNRNP40 TNKS1BP1 RPA1 AKAP12 TBCD	3.12e-04	533	84	7	25544563
Pubmed	Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.	ZSCAN20 SNRNP40	3.13e-04	11	84	2	16429158
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	WAPL MYCBP2 MAP3K20 DOCK7 TNKS1BP1	3.39e-04	247	84	5	32989298
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SCAF1 STRBP SNRNP40 SMARCC1 PRPF38B	3.65e-04	251	84	5	31076518
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MYCBP2 ANAPC1 STRBP STAU2 DOCK7 SMARCC1 SPATS2 AKAP12	3.68e-04	724	84	8	36232890
Pubmed	Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.	SMARCC1 RPA1	3.75e-04	12	84	2	15140983
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	LIG1 CADM4 MAP3K20 DOCK7 WDR1 SNAPC4 RPA1 IMMT FAF1 AKAP12	3.78e-04	1124	84	10	21900206
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	LIMA1 MYCBP2 MAP3K20 DOCK7 PRPF38B	3.92e-04	255	84	5	15324660
Pubmed	Global phosphoproteome of HT-29 human colon adenocarcinoma cells.	LIMA1 SMARCC1 PRPF38B	4.01e-04	59	84	3	16083285
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	DOCK7 SMARCC1 TNKS1BP1 SPATS2 WDR1 RPA1	4.20e-04	399	84	6	37536630
Pubmed	SPIDR is required for homologous recombination during mammalian meiosis.	RPA1 DDX4	4.42e-04	13	84	2	36938872
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	LIMA1 STAU2 ZNF185 SCP2 SMARCC1 WDR1 IMMT FAF1 AKAP12 SLC27A4 TBCD	4.45e-04	1367	84	11	32687490
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	LIMA1 MYCBP2 DNAAF10 GYS1 STAU2 DOCK7 WDR1 RPA1 FAF1 AKAP12	4.49e-04	1149	84	10	35446349
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	LIMA1 CTTNBP2 NDUFAF1 DNAAF10 GYS1 HERC1 RPA1	4.81e-04	573	84	7	28330616
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	ZNF106 LIMA1 STAU2 MAP3K20 DOCK7 SPATS2	4.85e-04	410	84	6	26949251
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	LIG1 DNAAF10 SMARCC1 AKAP12	5.29e-04	153	84	4	26365490
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZNF106 MAN2B1 ZFYVE16 MYCBP2 HERC1 FAF1 TBCD	5.78e-04	591	84	7	15231748
Pubmed	Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.	DNAAF10 DOCK7 SMARCC1	6.08e-04	68	84	3	14676191
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SCAF1 WAPL ANAPC1 DOCK7 SNRNP40 SMARCC1 CMYA5 PPAT RPA1 IMMT SLC27A4	6.28e-04	1425	84	11	30948266
Pubmed	Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?	SMARCC1 DDX4	6.77e-04	16	84	2	16787967
Pubmed	Which DNA polymerases are used for DNA-repair in eukaryotes?	LIG1 RPA1	6.77e-04	16	84	2	9111189
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	WAPL DOCK7 SMARCC1 TNKS1BP1 FAF1	6.81e-04	288	84	5	23383273
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ZNF106 LIMA1 STAU2 ZNF185 TNKS1BP1 RPA1	7.35e-04	444	84	6	34795231
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	LIMA1 CTTNBP2 ANAPC1 DNAAF10 MAP3K20 DOCK7	7.52e-04	446	84	6	24255178
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	YJU2 WAPL ANAPC1 SNRNP40 SMARCC1 PRPF38B WDR1 RPA1 IMMT	7.65e-04	1014	84	9	32416067
Pubmed	Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.	SH3BP2 TNKS1BP1	7.66e-04	17	84	2	22153077
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	SCAF1 WAPL DNAAF10 SNRNP40 PRPF38B	8.18e-04	300	84	5	28561026
Pubmed	Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome.	RPA1 DDX4	8.60e-04	18	84	2	31358751
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	LIMA1 STAU2 ZNF185 MAP3K20 DOCK7 SNRNP40 TNKS1BP1 SPATS2 WDR1 IMMT	8.96e-04	1257	84	10	36526897
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	NEK1 DNAAF10 SH3BP2 GYS1 MAP3K20 DOCK7 SNRNP40 TNKS1BP1 SPATS2	9.02e-04	1038	84	9	26673895
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	WAPL MAN2B1 STRBP DOCK7 SMARCC1 TASOR SLC27A4	1.01e-03	650	84	7	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYCBP2 ANAPC1 STRBP DOCK7 SMARCC1 TNKS1BP1 IMMT	1.03e-03	653	84	7	22586326
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	LIMA1 DOCK7 SNRNP40 TNKS1BP1 WDR1 RPA1 IMMT	1.10e-03	660	84	7	32780723
Pubmed	Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis.	RPA1 DDX4	1.17e-03	21	84	2	30272023
Pubmed	SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.	LIG1 RPA1	1.17e-03	21	84	2	24958773
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	WAPL DNAAF10 MAP3K9 SMARCC1 TMPRSS2 HERC1 RPA1 TASOR AKAP12	1.22e-03	1084	84	9	11544199
Pubmed	A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.	NEK1 CTTNBP2 ANAPC1 BCORL1 TBCD	1.27e-03	331	84	5	19490893
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	LIMA1 DOCK7 SNRNP40 TNKS1BP1 WDR1	1.32e-03	334	84	5	30425250
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	LIG1 MYCBP2 BCORL1 SNRNP40 SCP2 SMARCC1 PRPF38B PPAT RPA1	1.38e-03	1103	84	9	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SCAF1 MAN2B1 MYCBP2 ZNF335 LRP4 TNKS1BP1 HERC1 SNAPC4 TBCD	1.39e-03	1105	84	9	35748872
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ELAPOR2 NEK1 ZNF335 BCORL1 PRPF38B AKAP12 TBCD	1.41e-03	689	84	7	36543142
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	LIMA1 WAPL STRBP SNRNP40 RPA1	1.42e-03	340	84	5	24332808
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	LIMA1 YJU2 DOCK7 SNRNP40 SMARCC1 WDR1	1.44e-03	506	84	6	30890647
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	WAPL SMARCC1 RPA1 DDX4	1.51e-03	203	84	4	22083510
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	ZNF106 STAU2 SPATS2 IMMT	1.51e-03	203	84	4	35012549
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	WAPL MYCBP2 ZNF185 MAP3K20 SNRNP40 SMARCC1 WDR1 RPA1 IMMT SLC27A4	1.56e-03	1353	84	10	29467282
Pubmed	A protein interaction framework for human mRNA degradation.	NEK1 WAPL WDR1 SNAPC4 IMMT	1.56e-03	347	84	5	15231747
Pubmed	Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.	WBP4 STAU2 SCP2 LRP4 SPATS2 PPAT MSTO1	1.59e-03	704	84	7	32994395
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ZFYVE16 SH3D19 DOCK7 TNKS1BP1 RPA1 IMMT AKAP12	1.64e-03	708	84	7	39231216
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	MYCBP2 FAF1 SLC27A4 TBCD	1.68e-03	209	84	4	26389662
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	NEK1 STAU2 DOCK7 TNKS1BP1	1.68e-03	209	84	4	36779422
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SCAF1 STRBP STAU2 MAP3K20 DOCK7 SNRNP40 SMARCC1 PRPF38B SPATS2 RPA1	1.71e-03	1371	84	10	36244648
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SH3D19 STAU2 ZNF185 LRP4 HERC1 AKAP12 TBCD	1.79e-03	719	84	7	35337019
Pubmed	CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.	LIG1 HCLS1 SLC27A4 TBCD	1.80e-03	213	84	4	29615496
Pubmed	ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.	ZNF185 TNKS1BP1	1.80e-03	26	84	2	25228645
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SCAF1 MYCBP2 MAP3K20 TMPRSS2 PRPF38B	1.85e-03	361	84	5	26167880
Interaction	FMO5 interactions	FMO3 FMO5 HERC1	7.63e-06	10	82	3	int:FMO5
Interaction	PHF21A interactions	NEK1 ZFYVE16 MYCBP2 ANAPC1 BCORL1 DOCK7 SNRNP40 TNKS1BP1 RPA1	1.06e-05	343	82	9	int:PHF21A
Interaction	KDM1A interactions	NEK1 ZFYVE16 MYCBP2 ANAPC1 SH3D19 BCORL1 DOCK7 SMARCC1 ZNF480 TNKS1BP1 RPA1 TASOR IMMT MSTO1	2.41e-05	941	82	14	int:KDM1A
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC18 ZDHHC9 ZDHHC14	3.87e-05	24	50	3	76
GeneFamily	WD repeat domain containing	DNAI1 DNAAF10 CDC20B SNRNP40 WDR1 HERC1	8.14e-05	262	50	6	362
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	ZSCAN20 SMARCC1 SNAPC4	4.23e-04	53	50	3	532
GeneFamily	EF-hand domain containing\|Nucleotide excision repair\|Transcription and export complex 2	LIG1 RPA1	1.11e-03	18	50	2	1269
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K20 MAP3K9	1.99e-03	24	50	2	654
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	CMYA5 AKAP12	2.90e-03	29	50	2	396
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE16 RUFY4	3.31e-03	31	50	2	81
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FMO3 TMPRSS2 CNTN3 DDX4 RUFY4	1.24e-05	160	83	5	9049707a4487f2337a17976ceb5fbd8815ab9e1d
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FMO3 TMPRSS2 CNTN3 DDX4 RUFY4	1.24e-05	160	83	5	f2cfec54cf48a655f473b830be7d141c54b521ff
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FMO3 TMPRSS2 CNTN3 DDX4 RUFY4	1.24e-05	160	83	5	0eb50b3c494e1b65d40104b3b5411b57bb72b959
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF106 MYCBP2 SMARCC1 TASOR AKAP12	2.43e-05	184	83	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAI1 ODAD1 ZNF185 TMPRSS2 SPATS2	2.49e-05	185	83	5	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF106 LIMA1 WAPL STRBP TASOR	2.90e-05	191	83	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF106 LIMA1 WAPL STRBP TASOR	2.90e-05	191	83	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF106 LIMA1 WAPL STRBP TASOR	2.90e-05	191	83	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ELAPOR2 FMO5 ZDHHC9 SLC34A2 TMPRSS2	3.29e-05	196	83	5	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 FMO5 ZDHHC9 SLC34A2 TMPRSS2	3.37e-05	197	83	5	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 FMO5 ZDHHC9 SLC34A2 TMPRSS2	3.37e-05	197	83	5	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	(06)_OLFM4+\|World / shred by cell type by condition	PXDN ZDHHC9 STAU2 SLC34A2 TMPRSS2	3.53e-05	199	83	5	c773b9180dbfec9c19d4098dd43332e6f6050372
Disease	inherited metabolic disorder (is_implicated_in)	LIG1 FMO3 SUOX	8.85e-06	15	81	3	DOID:655 (is_implicated_in)
Disease	Left ventricular mass to end-diastolic volume ratio	PXDN FAF1	2.14e-03	25	81	2	EFO_0010556

Protein segments in the cluster

Peptide	Gene	Start	Entry
WTGKEITDGEEKTEG	CNPY4	201	Q8N129
EEVITGSGKNSWKSE	DDX4	216	Q9NQI0
ATSDGEKKREGVTPW	AKAP12	596	Q02952
STKSGKVLVVWDETS	SH3BP2	491	P78314
SEEAKGKGRWSQQKT	BCORL1	1431	Q5H9F3
GETSKWDRNSQGDVK	DOP1A	716	Q5JWR5
GEGTDEWAQSKATVR	DNAI1	36	Q9UI46
GDLVDSKTWGKSTET	POLN	31	Q7Z5Q5
KVTWTEAAGSIRDGV	CRYZL1	116	O95825
QVSDSGDIKIKSWRG	KIAA1107	36	Q9UPP5
KESWQLRKGVSEIGE	ANAPC1	71	Q9H1A4
TTGQWDVTTERDGKK	FMO3	121	P31513
KSLGSSREAEGWKED	MAGEB18	91	Q96M61
TTWQNKESKGETGKR	LIMA1	651	Q9UHB6
KSVSSDRKKWEAGGQ	NEK1	751	Q96PY6
WVGRIKSKTDGGTTD	IGHV3-15	66	A0A0B4J1V0
HWETTLTEGKKQRET	FAM149A	476	A5PLN7
GVVKEGSTSAKVQWD	HERC1	2336	Q15751
EIVTGSRDGTVKVWD	DNAAF10	131	Q96MX6
AEGVLSSDGVWRVKS	MSTO1	121	Q9BUK6
AGEKKSAQWRTVEGA	IMMT	266	Q16891
SWAEVRKSGASVKVS	IGHV1-38-4	26	P0DTW3
KQAGEVAEGVWKTSQ	ODAD1	246	Q96M63
KSTNVVESWGGTKEK	ELAPOR2	536	A8MWY0
WTGDTSSDQLVLGKK	ITPRIPL1	76	Q6GPH6
KSQIRTWSNSRGEGK	RPA1	206	P27694
EVEISTGERKGSWSE	DOCK7	421	Q96N67
EAGTNRSVKTTDGWT	CTTNBP2	831	Q8WZ74
ATSGQWEVVTESEGK	FMO5	121	P49326
ESELWKGGSVDITKE	CMYA5	2766	Q8N3K9
WTVTSDKTIGGRSEV	NDUFAF1	136	Q9Y375
DWRSKGAVTKVKDQG	CTSF	276	Q9UBX1
KGVSSSQENGKVWSV	CADM4	166	Q8NFZ8
WEGSSQGRTKPTEKS	AGAP7P	521	Q5VUJ5
ASEEDSKVSEGGWTK	MAP3K20	756	Q9NYL2
VGDTWGKEVISRFDT	MAN2B1	721	O00754
GTSEGEVQLWDVVTK	CDC20B	291	Q86Y33
TTRVNSWVADKTKGE	HMSD	101	A8MTL9
LLKGWKTGDVEDSTV	FAF1	141	Q9UNN5
VLQTKAKVTGDEWGD	GYS1	46	P13807
VDAGKGKTAEARKTW	LIG1	481	P18858
GKTAEARKTWLEEQG	LIG1	486	P18858
DSKSNEKAEEWGRSG	SAA4	101	P35542
SSWKKGDVSVQEHER	CNTN3	441	Q9P232
KTWGRSSVVPKEEGE	MAP3K9	571	P80192
VKGGTWSQAEKATSL	PCARE	936	A6NGG8
GEWDSGTENRLKVTS	SH3D19	66	Q5HYK7
ISEKEQRWGAKTIEG	HCLS1	31	P14317
KTVAVWDSETGERVK	SNRNP40	131	Q96DI7
QRTTEGTHKKEAEWS	RUFY4	326	Q6ZNE9
DQSGKIISRTWADGK	TENM1	1866	Q9UKZ4
SDWLDETNKGTKTEG	STRBP	46	Q96SI9
GWKDGESTKIAGQIS	MYCBP2	3871	O75592
GDVSGKLRIWDTTQK	WDR1	76	O75083
EATWVVDVKNGKGSV	SCP2	471	P22307
LAKSKGASAGREWTE	SMARCC1	611	Q92922
SEIWEKETKGSRGTD	TASOR	1526	Q9UK61
QDSGIKWSERDTKGK	SLC34A2	76	O95436
EGSASEVLKEWTVTG	SPATS2	71	Q86XZ4
ISGWGATEEKGKTSE	TMPRSS2	381	O15393
TNEDIKGSWTGKNRV	ZDHHC9	256	Q9Y397
GSESKLWEKDRGSVS	ZSCAN20	31	P17040
SSDKSVKVWDVGTRT	WDR61	251	Q9GZS3
GQKKSLSVWQRSGEE	MLN	46	P12872
LGEQTWESEGSSIKK	STAU2	46	Q9NUL3
GDTFRWKGENVSTTE	SLC27A4	506	Q6P1M0
WKGENVSTTEVEGTL	SLC27A4	511	Q6P1M0
TKGAEETSWSGEERA	SCAF1	956	Q9H7N4
VEPWEKGSRKTAGQT	PRPF38B	96	Q5VTL8
GVGEKDWTSDVNVKS	TNKS1BP1	1221	Q9C0C2
EKKTSETEGWVVSSE	PPAT	221	Q06203
ITWNKDGVQVTESGK	PXDN	556	Q92626
KDPSKGRWVEGITSE	WBP4	121	O75554
SGEIQWVSTEKTDGT	WAPL	1076	Q7Z5K2
GIKKEKTGWDTSESE	PRPF40B	836	Q6NWY9
KRKVEVWEQSVGSLG	YJU2	241	Q9BW85
TTNEDIKGSWSNKRG	ZDHHC14	281	Q8IZN3
WSGESEVKIAKNSDG	ZNF480	86	Q8WV37
SGSWQEAGTSAKDKR	SNAPC4	966	Q5SXM2
DKDTVVRWSAAKGIG	TBCD	371	Q9BTW9
KEVKGLEWRTGAIST	SUOX	276	P51687
NVGTGEKKVTEAWIS	ZNF623	11	O75123
RKWSTSTKSQEEEGP	ZNF335	286	Q9H4Z2
GKDVATKVGEAWQDR	ZNF185	476	O15231
IKGGKVTTSTWEDSR	ZNF106	1391	Q9H2Y7
EDIKGSWSSKRGGEA	ZDHHC18	311	Q9NUE0
WVDAEEKGNKGVISS	ZFYVE16	1386	Q7Z3T8
KWDGTGQEVVVDTSL	LRP4	801	O75096