Histone H2A-like 3 (H2A.L.3)
1_MAGNK 6_ MFCRP 11_ RRQRL 16_ SHSRR 21_ AELQF 26_ PVSHL 31_ ERCLR 36_ ESQHA 41_ RHLSS 46_ TTPVF 51_ LAGVL 56_ EYLTA 61_ NILEK 66_ VGKEV 71_ KNSCR 76_ LCITP 81_ EHVKR 86_ ALQKD 91_ EQLRW 96_ ILELE 101_ DDTHS 106_ QVEEM 111_ PQSEE 116_ EEEEE 121_ EEKEE 126_ EMVVL 131_ VVMGG 136_ RRRRR 141_RRRRR
1: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling