RNA-binding protein 47 (RNA-binding motif protein 47)
1_MTAED 6_ STAAM 11_ SSDSA 16_ AGSSA 21_ KVPEG 26_ VAGAP 31_ NEAAL 36_ LALME 41_ RTGYS 46_ MVQEN 51_ GQRKY 56_ GGPPP 61_ GWEGP 66_ HPQRG 71_ CEVFV 76_ GKIPR 81_ DVYED 86_ ELVPV 91_ FEAVG 96_ RIYEL 101_ RLMMD 106_ FDGKN 111_ RGYAF 116_ VMYCH 121_ KHEAK 126_ RAVRE 131_ LNNYE 136_ IRPGR 141_ LLGVC 146_ CSVDN 151_ CRLFI 156_ GGIPK 161_ MKKRE 166_ EILEE 171_ IAKVT 176_ EGVLD 181_ VIVYA 186_ SAADK 191_ MKNRG 196_ FAFVE 201_ YESHR 206_ AAAMA 211_ RRKLM 216_ PGRIQ 221_ LWGHQ 226_ IAVDW 231_ AEPEI 236_ DVDED 241_ VMETV 246_ KILYV 251_ RNLMI 256_ ETTED 261_ TIKKS 266_ FGQFN 271_ PGCVE 276_ RVKKI 281_ RDYAF 286_ VHFTS 291_ REDAV 296_ HAMNN 301_ LNGTE 306_ LEGSC 311_ LEVTL 316_ AKPVD 321_ KEQYS 326_ RYQKA 331_ ARGGG 336_ AAEAA 341_ QQPSY 346_ VYSCD 351_ PYTLA 356_ YYGYP 361_ YNALI 366_ GPNRD 371_ YFVKA 376_ GSIRG 381_ RGRGA 386_ AGNRA 391_ PGPRG 396_ SYLGG 401_ YSAGR 406_ GIYSR 411_ YHEGK 416_ GKQQE 421_ KGYEL 426_ VPNLE 431_ IPTVN 436_ PVAIK 441_ PGTVA 446_ IPAIG 451_ AQYSM 456_ FPAAP 461_ APKMI 466_ EDGKI 471_ HTVEH 476_ MISPI 481_ AVQPD 486_ PASAA 491_ AAAAA 496_ AAAAA 501_ AAVIP 506_ TVSTP 511_ PPFQG 516_ RPITP 521_ VYTVA 526_ PNVQR 531_ IPTAG 536_ IYGAS 541_ YVPFA 546_ APATA 551_ TIATL 556_ QKNAA 561_ AAAAM 566_ YGGYA 571_ GYIPQ 576_ AFPAA 581_ AIQVP 586_IPDVY
1: Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing (PubMed:24038582, PubMed:24916387, PubMed:27050523, PubMed:30844405, PubMed:31358901, PubMed:34160127). Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules (PubMed:24038582, PubMed:24916387, PubMed:30844405). Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10 (PubMed:34160127). Also involved in the alternative splicing of several genes including TJP1. Binds the pre-mRNA (U)GCAUG consensus sequences in downstream intronic regions of alternative exons, regulating their exclusion and inclusion into mRNAs (PubMed:27050523, PubMed:31358901). Independently of its RNA-binding activity, could negatively regulate MAVS by promoting its lysosomal degradation (By similarity)