Odontogenic ameloblast-associated protein (Apin)
1_MKIII 6_ LLGFL 11_ GATLS 16_ APLIP 21_ QRLMS 26_ ASNSN 31_ ELLLN 36_ LNNGQ 41_ LLPLQ 46_ LQGPL 51_ NSWIP 56_ PFSGI 61_ LQQQQ 66_ QAQIP 71_ GLSQF 76_ SLSAL 81_ DQFAG 86_ LLPNQ 91_ IPLTG 96_ EASFA 101_ QGAQA 106_ GQVDP 111_ LQLQT 116_ PPQTQ 121_ PGPSH 126_ VMPYV 131_ FSFKM 136_ PQEQG 141_ QMFQY 146_ YPVYM 151_ VLPWE 156_ QPQQT 161_ VPRSP 166_ QQTRQ 171_ QQYEE 176_ QIPFY 181_ AQFGY 186_ IPQLA 191_ EPAIS 196_ GGQQQ 201_ LAFDP 206_ QLGTA 211_ PEIAV 216_ MSTGE 221_ EIPYL 226_ QKEAI 231_ NFRHD 236_ SAGVF 241_ MPSTS 246_ PKPST 251_ TNVFT 256_ SAVDQ 261_ TITPE 266_ LPEEK 271_DKTDS
1: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface