Xin actin-binding repeat-containing protein 2 (Beta-xin) (Cardiomyopathy-associated protein 3) (Xeplin)
1_MSPES 6_ GHSRI 11_ FEATA 16_ GPNKP 21_ ESGFA 26_ EDSAA 31_ RGEGV 36_ SDLHE 41_ VVSLK 46_ ERMAR 51_ YQAAV 56_ SRGDC 61_ RSFSA 66_ NMMEE 71_ SEMCA 76_ VPGGL 81_ AKVKK 86_ QFEDE 91_ ITSSR 96_ NTFAQ 101_ YQYQH 106_ QNRSE 111_ QEAIH 116_ SSQVG 121_ TSRSS 126_ QEMAR 131_ NEQEG 136_ SKVQK 141_ IDVHG 146_ TEMVS 151_ HLEKH 156_ TEEVN 161_ QASQF 166_ HQYVQ 171_ ETVID 176_ TPEDE 181_ EIPKV 186_ STKLL 191_ KEQFE 196_ KSAQE 201_ KILYS 206_ DKEMT 211_ TPAKQ 216_ IKTES 221_ EYEET 226_ FKPSS 231_ VVSTS 236_ STSCV 241_ STSQR 246_ KETST 251_ TRYSD 256_ HSVTS 261_ STLAQ 266_ INATS 271_ SGMTE 276_ EFPPP 281_ PPDVL 286_ QTSVD 291_ VTAFS 296_ QSPEL 301_ PSPPR 306_ RLPVP 311_ KDVYS 316_ KQRNL 321_ YELNR 326_ LYKHI 331_ HPELR 336_ KNLEK 341_ DYISE 346_ VSEIV 351_ SSQMN 356_ SGSSV 361_ SADVQ 366_ QARYV 371_ FENTN 376_ DSSQK 381_ DLNSE 386_ REYLE 391_ WDEIL 396_ KGEVQ 401_ SIRWI 406_ FENQP 411_ LDSIN 416_ NGSPD 421_ EGDIS 426_ RGIAD 431_ QEIIA 436_ GGDVK 441_ YTTWM 446_ FETQP 451_ IDTLG 456_ AYSSD 461_ TVENA 466_ EKIPE 471_ LARGD 476_ VCTAR 481_ WMFET 486_ RPLDS 491_ MNKMH 496_ QSQEE 501_ SAVTI 506_ SKDIT 511_ GGDVK 516_ TVRYM 521_ FETQH 526_ LDQLG 531_ QLHSV 536_ DEVHL 541_ LQLRS 546_ ELKEI 551_ KGNVK 556_ RSIKC 561_ FETQP 566_ LYVIR 571_ DGSGQ 576_ MLEIK 581_ TVHRE 586_ DVEKG 591_ DVRTA 596_ RWMFE 601_ TQPLD 606_ TINKD 611_ ITEIK 616_ VVRGI 621_ SMEEN 626_ VKGGV 631_ SKAKW 636_ LFETQ 641_ PLEKI 646_ KESEE 651_ VIIEK 656_ EKIIG 661_ TDVSR 666_ KCWMF 671_ ETQPL 676_ DILKE 681_ VPDAD 686_ SLQRE 691_ EIIGG 696_ DVQTT 701_ KHLFE 706_ TLPIE 711_ ALKDS 716_ PDIGK 721_ LQKIT 726_ ASEEE 731_ KGDVR 736_ HQKWI 741_ FETQP 746_ LEDIR 751_ KDKKE 756_ YTRTV 761_ KLEEV 766_ DRGDV 771_ KNYTH 776_ IFESN 781_ NLIKF 786_ DASHK 791_ IEVEG 796_ VTRGA 801_ VELNK 806_ SLFET 811_ TPLYA 816_ IQDPL 821_ GKYHQ 826_ VKTVQ 831_ QEEIV 836_ RGDVR 841_ SCRWL 846_ FETRP 851_ IDQFD 856_ ESIHK 861_ FQIIR 866_ GISAQ 871_ EIQTG 876_ NVKSA 881_ KWLFE 886_ TQPLD 891_ SIKYF 896_ SDVEE 901_ TESKT 906_ EQTRD 911_ IVKGD 916_ VKTCK 921_ WLFET 926_ QPMES 931_ LYEKV 936_ SLMTS 941_ SEEIH 946_ KGDVK 951_ TCTWL 956_ FETQP 961_ LDTIK 966_ DDSET 971_ AVKLQ 976_ TVKQE 981_ EIQGG 986_ DVRTA 991_ CFLFE 996_ TENLD 1001_ SIQGE 1006_ EVKEI 1011_ KPVEM 1016_ DIQAG 1021_ DVSSM 1026_ RYKFE 1031_ NQSLD 1036_ SISSS 1041_ SEEVL 1046_ KKIKT 1051_ LKTED 1056_ IQKGN 1061_ VLNCR 1066_ WLFEN 1071_ QPIDK 1076_ IKESQ 1081_ EGDEC 1086_ VKTVT 1091_ DIQGG 1096_ DVRKG 1101_ CFIFE 1106_ TFSLD 1111_ EIKEE 1116_ SDYIS 1121_ TKKTI 1126_ TEEVI 1131_ QGDVK 1136_ SYRML 1141_ FETQP 1146_ LYAIQ 1151_ DREGS 1156_ YHEVT 1161_ TVKKE 1166_ EVIHG 1171_ DVRGT 1176_ RWLFE 1181_ TKPLD 1186_ SINKS 1191_ ETVYV 1196_ IKSVT 1201_ QEDIQ 1206_ KGDVS 1211_ SVRYR 1216_ FETQP 1221_ LDQIS 1226_ EESHN 1231_ IMPSI 1236_ DHIQG 1241_ GNVKT 1246_ SRQFF 1251_ ESENF 1256_ DKNNY 1261_ IRTVS 1266_ VNEIQ 1271_ KGNVK 1276_ TSTWL 1281_ FETHT 1286_ MDELR 1291_ GEGLE 1296_ YENIK 1301_ TVTQE 1306_ DVQKG 1311_ DVKQA 1316_ VWLFE 1321_ NRTFD 1326_ SIMEA 1331_ HKGIT 1336_ KMTKE 1341_ EIPPS 1346_ DVKTT 1351_ TWLFE 1356_ TTPLH 1361_ EFNET 1366_ RVEKI 1371_ EIIGK 1376_ SIKET 1381_ LEDLY 1386_ SQKVI 1391_ QAPGI 1396_ IIEAD 1401_ EIGDV 1406_ RMAKY 1411_ KLMNQ 1416_ ASPEI 1421_ QKEEI 1426_ IRADL 1431_ RNIMV 1436_ NLLSK 1441_ RDCTE 1446_ REILI 1451_ SEEEK 1456_ GNVNL 1461_ TKTQL 1466_ LNRST 1471_ EFHAE 1476_ KEEIV 1481_ KGDVQ 1486_ QAIKN 1491_ LFSEE 1496_ RSVKK 1501_ GILIQ 1506_ EDEKG 1511_ DINMT 1516_ IYCLL 1521_ HENDG 1526_ DTIER 1531_ EEVIG 1536_ GDVKR 1541_ TIHNL 1546_ LSSTS 1551_ NNKIS 1556_ ERAKI 1561_ DASER 1566_ GNVQF 1571_ FTTCI 1576_ EAGAL 1581_ DYLKQ 1586_ LHTES 1591_ NETLT 1596_ AKKQE 1601_ GEKEI 1606_ IGGDV 1611_ EGTKL 1616_ LLKKR 1621_ QSLVE 1626_ RTVSE 1631_ TDIIP 1636_ GDVHN 1641_ TVKVF 1646_ MTEPQ 1651_ STFGK 1656_ IPKEE 1661_ IIKGD 1666_ LTSTL 1671_ NSLSQ 1676_ AVNQK 1681_ TVTKT 1686_ EEIIK 1691_ GNMLA 1696_ TLKSL 1701_ KESSH 1706_ RWKES 1711_ KQPDA 1716_ IPGDI 1721_ EKAIE 1726_ CLEKA 1731_ TNTKT 1736_ EILKK 1741_ ELLKD 1746_ DLETS 1751_ LRSLK 1756_ EAQRS 1761_ FKEVH 1766_ KEGVI 1771_ KKDAK 1776_ AVMAG 1781_ SSGEQ 1786_ KTDIH 1791_ QVAVQ 1796_ RNKNS 1801_ LLQPK 1806_ PGPFE 1811_ PAAKW 1816_ QGGAD 1821_ TLSQT 1826_ MGKSC 1831_ HGNLV 1836_ EERTE 1841_ VNLPK 1846_ APKGT 1851_ VKIVI 1856_ DREQN 1861_ NDALE 1866_ KSLRR 1871_ LSNSH 1876_ HKSNV 1881_ LESGD 1886_ KTGVW 1891_ TDTTG 1896_ EQHLR 1901_ DEYMS 1906_ RQLTS 1911_ TVSVK 1916_ NNLTT 1921_ KESDR 1926_ AVREL 1931_ KKDDV 1936_ FNSIQ 1941_ SAGKT 1946_ VGKQQ 1951_ TYELR 1956_ NDHQK 1961_ MEGFH 1966_ IKSPK 1971_ KTKNI 1976_ KILTD 1981_ TQSSK 1986_ PSPTQ 1991_ HPVSM 1996_ PVGGT 2001_ YDLSG 2006_ DFQKQ 2011_ TLLKQ 2016_ ETKYS 2021_ NKDIK 2026_ KKNIN 2031_ LQPMW 2036_ QLLPV 2041_ EQDTS 2046_ NVTEM 2051_ KVSEK 2056_ SHNTF 2061_ KATNK 2066_ KRETD 2071_ VHLKS 2076_ QDFLM 2081_ KTNTS 2086_ TGLKM 2091_ AMERS 2096_ LNPIN 2101_ FNPEN 2106_ NVKES 2111_ ECPLP 2116_ PPSPP 2121_ PPPPS 2126_ NASSE 2131_ IEFPL 2136_ PPPPP 2141_ LMMFP 2146_ EKNGF 2151_ LPSLS 2156_ TEKIK 2161_ AEFES 2166_ FPGLP 2171_ LPPPP 2176_ VDEKS 2181_ ERESS 2186_ SMFLP 2191_ PPPPP 2196_ TPSQK 2201_ PAHLL 2206_ SSSAP 2211_ EKHSG 2216_ DFMQQ 2221_ YSQKE 2226_ ASNSQ 2231_ NSQAK 2236_ IITGK 2241_ TGVLP 2246_ PPTLP 2251_ KPKLP 2256_ KHIKD 2261_ NKNDF 2266_ SPKVE 2271_ LATSL 2276_ SDMEC 2281_ KITTS 2286_ KDQKK 2291_ VMVMT 2296_ SSEHT 2301_ ETKQN 2306_ VISKS 2311_ LDERK 2316_ QLSID 2321_ SANCL 2326_ SHTVP 2331_ GTSAP 2336_ RKKQI 2341_ APLIK 2346_ SHSFP 2351_ ESSGQ 2356_ QNPKP 2361_ YMRKF 2366_ KTPLM 2371_ IAEEK 2376_ YRQQK 2381_ EEIEK 2386_ QKQES 2391_ SYYNI 2396_ VKTQS 2401_ QNQHI 2406_ TEVEK 2411_ EMPLQ 2416_ KTNEE 2421_ VSLSG 2426_ IDSEC 2431_ TVVQP 2436_ SPGSQ 2441_ SNARI 2446_ LGVCS 2451_ DNQLS 2456_ TTSPE 2461_ TVAAK 2466_ RLHHV 2471_ LAASE 2476_ DKDKM 2481_ KKEVL 2486_ QSSRD 2491_ IMQSK 2496_ SACEI 2501_ KQSHQ 2506_ ECSTQ 2511_ QTQQK 2516_ KYLEQ 2521_ LHLPQ 2526_ SKPIS 2531_ PNFKV 2536_ KTIKL 2541_ PTLDH 2546_ TLNET 2551_ DHSYE 2556_ SHKQQ 2561_ SEIDV 2566_ QTFTK 2571_ KQYLK 2576_ TKKTE 2581_ ASTEC 2586_ SHKQS 2591_ LAERH 2596_ YQLPK 2601_ KEKRV 2606_ TVQLP 2611_ TESIQ 2616_ KNQED 2621_ KLKMV 2626_ PRKQR 2631_ EFSGS 2636_ DRGKL 2641_ PGSEE 2646_ KNQGP 2651_ SMIGR 2656_ KEERL 2661_ ITERK 2666_ HEHLK 2671_ NKSAP 2676_ KVVKQ 2681_ KVIDA 2686_ HLDSQ 2691_ TQNFQ 2696_ QTQIQ 2701_ TAESK 2706_ AEHKK 2711_ LPQPY 2716_ NSLQE 2721_ EKCLE 2726_ VKGIQ 2731_ EKQVF 2736_ SNTKD 2741_ SKQEI 2746_ TQNKS 2751_ FFSSV 2756_ KESQR 2761_ DDGKG 2766_ ALNIV 2771_ EFLRK 2776_ REELQ 2781_ QILSR 2786_ VKQFE 2791_ AEPNK 2796_ SGLKT 2801_ FQTLL 2806_ NTIPG 2811_ WLISE 2816_ DKREY 2821_ AVHIA 2826_ MENNL 2831_ EKVKE 2836_ EITHI 2841_ KTQAE 2846_ DMLVS 2851_ YENII 2856_ QTAMM 2861_ SSKTG 2866_ KPGNK 2871_ PTSLD 2876_ ETSSK 2881_ VSNVH 2886_ VSNNK 2891_ NSEQK 2896_ ENKIA 2901_ KEKTV 2906_ QHQVA 2911_ AHHEA 2916_ TVRSH 2921_ VKTHQ 2926_ EIKLD 2931_ DSNIP 2936_ PPSLK 2941_ TRPPS 2946_ PTFIT 2951_ IESTA 2956_ RRTEN 2961_ PTKNE 2966_ LSQSP 2971_ KKDSY 2976_ VEPPP 2981_ RRPMS 2986_ QKSEI 2991_ HRANT 2996_ SPSPP 3001_ RSRSE 3006_ QLVRL 3011_ KDTTA 3016_ KLSKG 3021_ AIPCP 3026_ AATPV 3031_ PIVEK 3036_ RSEII 3041_ MSPAT 3046_ LRRQI 3051_ KIETR 3056_ GRDSP 3061_ PTITI 3066_ PVNIN 3071_ HAASG 3076_ SFRES 3081_ VDAQE 3086_ EIRKV 3091_ EKRAT 3096_ YVHKD 3101_ GLNST 3106_ DHMVP 3111_ DTESY 3116_ DAVEI 3121_ IRKVA 3126_ VPPRL 3131_ SEHTQ 3136_ RYEAA 3141_ NRTVQ 3146_ MAENF 3151_ VNDPE 3156_ NEINR 3161_ WFREF 3166_ EHGPV 3171_ SEAKS 3176_ NRRVY 3181_ AKGET 3186_ NHNIQ 3191_ QESRT 3196_ FCKEE 3201_ FGLTS 3206_ LGNTS 3211_ FTDFS 3216_ CKHPR 3221_ ELREK 3226_ IPVKQ 3231_ PRICS 3236_ ETRSL 3241_ SEHFS 3246_ GMDAF 3251_ ESQIV 3256_ ESKMK 3261_ TSSSH 3266_ SSEAG 3271_ KSGCD 3276_ FKHAP 3281_ PTYED 3286_ VIAGH 3291_ ILDIS 3296_ DSPKE 3301_ VRKNF 3306_ QKTWQ 3311_ ESGRV 3316_ FKGLG 3321_ YATAD 3326_ ASATE 3331_ MRTTF 3336_ QEESA 3341_ FISEA 3346_ AAPRQ 3351_ GNMYT 3356_ LSKDS 3361_ LSNGV 3366_PSGRQ
1: Protects actin filaments from depolymerization (PubMed:15454575). Required for correct morphology of cell membranes and maturation of intercalated disks of cardiomyocytes via facilitating localization of XIRP1 and CDH2 to the termini of aligned mature cardiomyocytes (By similarity). Thereby required for correct postnatal heart development and growth regulation that is crucial for overall heart morphology and diastolic function (By similarity). Required for normal electrical conduction in the heart including formation of the infranodal ventricular conduction system and normal action potential configuration, as a result of its interaction with the cardiac ion channel components Scn5a/Nav1.5 and Kcna5/Kv1.5 (By similarity). Required for regular actin filament spacing of the paracrystalline array in both inner and outer hair cells of the cochlea, thereby required for maintenance of stereocilia morphology (By similarity)