Plasmanylethanolamine desaturase (EC 1.14.19.77) (Plasmanylethanolamine desaturase 1) (Transmembrane protein 189)
1_MAGAE 6_ NWPGQ 11_ QLELD 16_ EDEAS 21_ CCRWG 26_ AQHAG 31_ ARELA 36_ ALYSP 41_ GKRLQ 46_ EWCSV 51_ ILCFS 56_ LIAHN 61_ LVHLL 66_ LLARW 71_ EDTPL 76_ VILGV 81_ VAGAL 86_ IADFL 91_ SGLVH 96_ WGADT 101_ WGSVE 106_ LPIVG 111_ KAFIR 116_ PFREH 121_ HIDPT 126_ AITRH 131_ DFIET 136_ NGDNC 141_ LVTLL 146_ PLLNM 151_ AYKFR 156_ THSPE 161_ ALEQL 166_ YPWEC 171_ FVFCL 176_ IIFGT 181_ FTNQI 186_ HKWSH 191_ TYFGL 196_ PRWVT 201_ LLQDW 206_ HVILP 211_ RKHHR 216_ IHHVS 221_ PHETY 226_ FCITT 231_ GWLNY 236_ PLEKI 241_ GFWRR 246_ LEDLI 251_ QGLTG 256_ EKPRA 261_DDMKW
1: Plasmanylethanolamine desaturase involved in plasmalogen biogenesis in the endoplasmic reticulum membrane (PubMed:31604315, PubMed:32209662, PubMed:33859415). Plasmalogens are glycerophospholipids with a hydrocarbon chain linked by a vinyl ether bond at the glycerol sn-1 position, and are involved in antioxidative and signaling mechanisms (PubMed:31604315)