Gene name: NUPR2

Uniprot entry:

A6NF83

Protein names:

Nuclear protein 2 (Nuclear transcriptional regulator 1-like protein) (Nuclear transcriptional regulator protein 2)

Protein sequence:

1_MEAPA 6_ ERALP 11_ RLQAL 16_ ARPPP 21_ PISYE 26_ EELYD 31_ CLDYY 36_ YLRDF 41_ PACGA 46_ GRSKG 51_ RTRRE 56_ QALRT 61_ NWPAP 66_ GGHER 71_ KVAQK 76_ LLNGQ 81_ RKRRQ 86_ RQLHP 91_KMRTR

Protein annotations

Protein functions:

1: Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells (PubMed:25899918). Involved in the G1 cell cycle arrest, and in a decrease in cell viability and cell proliferation (PubMed:25899918). Plays a role as a negative regulator of the protumoral factor NUPR1 (PubMed:25899918)