Protein myomaker (Myoblast fusion maker) (Transmembrane protein 226) (Transmembrane protein 8C)
1_MGTLV 6_ AKLLL 11_ PTLSS 16_ LAFLP 21_ TVSIA 26_ AKRRF 31_ HMEAM 36_ VYLFT 41_ LFFVA 46_ LHHAC 51_ NGPGL 56_ SVLCF 61_ MRHDI 66_ LEYFS 71_ VYGTA 76_ LSMWV 81_ SLMAL 86_ ADFDE 91_ PKRST 96_ FVMFG 101_ VLTIA 106_ VRIYH 111_ DRWGY 116_ GVYSG 121_ PIGTA 126_ ILIIA 131_ AKWLQ 136_ KMKEK 141_ KGLYP 146_ DKSVY 151_ TQQIG 156_ PGLCF 161_ GALAL 166_ MLRFF 171_ FEDWD 176_ YTYVH 181_ SFYHC 186_ ALAMS 191_ FVLLL 196_ PKVNK 201_ KAGSP 206_ GTPAK 211_ LDCST 216_LCCAC
1: Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers (PubMed:28681861). Actively participates in the membrane fusion reaction by mediating the mixing of cell membrane lipids (hemifusion) upstream of MYMX. Acts independently of MYMX (By similarity). Involved in skeletal muscle regeneration in response to injury by mediating the fusion of satellite cells, a population of muscle stem cells, with injured myofibers (By similarity). Also involved in skeletal muscle hypertrophy, probably by mediating the fusion of satellite cells with myofibers (By similarity)