12S rRNA N4-methylcytidine (m4C) methyltransferase (12S rRNA m4C methyltransferase) (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15)
1_MLRYP 6_ YFCRM 11_ YKECL 16_ SCWLE 21_ SGIPN 26_ LGVWP 31_ NRIHT 36_ TAEKY 41_ REYEA 46_ REQTD 51_ QTQAQ 56_ ELHRS 61_ QDRDF 66_ ETMAK 71_ LHIPV 76_ MVDEV 81_ VHCLS 86_ PQKGQ 91_ IFLDM 96_ TFGSG 101_ GHTKA 106_ ILQKE 111_ SDIVL 116_ YALDR 121_ DPTAY 126_ ALAEH 131_ LSELY 136_ PKQIR 141_ AMLGQ 146_ FSQAE 151_ ALLMK 156_ AGVQP 161_ GTFDG 166_ VLMDL 171_ GCSSM 176_ QLDTP 181_ ERGFS 186_ LRKDG 191_ PLDMR 196_ MDGGR 201_ YPDMP 206_ TAADV 211_ VNALD 216_ QQALA 221_ SILRT 226_ YGEEK 231_ HAKKI 236_ ASAIV 241_ QARSI 246_ YPITR 251_ TQQLA 256_ SIVAG 261_ AFPPS 266_ AIYTR 271_ KDLLQ 276_ RSTHI 281_ ATKTF 286_ QALRI 291_ FVNNE 296_ LNELY 301_ TGLKT 306_ AQKFL 311_ RPGGR 316_ LVALS 321_ FHSLE 326_ DRIVK 331_ RFLLG 336_ ISMTE 341_ RFNLS 346_ VRQQV 351_ MKTSQ 356_ LGSDH 361_ ENTEE 366_ VSMRR 371_ APLMW 376_ ELIHK 381_ KVLSP 386_ QDQDV 391_ QDNPR 396_ GRSAK 401_LRAAI
1: N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA (PubMed:31665743, PubMed:32371392). Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits (PubMed:31665743, PubMed:32371392)