Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
1_METES 6_ ESSTL 11_ GDDSV 16_ FWLES 21_ EVIIQ 26_ VTDCE 31_ EEERE 36_ EKFRK 41_ MKSSV 46_ HSEED 51_ DFVPE 56_ LHRNV 61_ HPRER 66_ PDWEE 71_ TLSAM 76_ ARGAD 81_ VPEIP 86_ GDLTL 91_ KTCGS 96_ TASMK 101_ VKHVK 106_ KLPFT 111_ KGHFP 116_ KMAEC 121_ AHFHY 126_ ENVEF 131_ GSIQL 136_ SLSEE 141_ QNEVM 146_ KNGCE 151_ SKELV 156_ YLVQI 161_ ACQGK 166_ SWIVK 171_ RSYED 176_ FRVLD 181_ KHLHL 186_ CIYDR 191_ RFSQL 196_ SELPR 201_ SDTLK 206_ DSPES 211_ VTQML 216_ MAYLS 221_ RLSAI 226_ AGNKI 231_ NCGPA 236_ LTWME 241_ IDNKG 246_ NHLLV 251_ HEESS 256_ INTPA 261_ VGAAH 266_ VIKRY 271_ TARAP 276_ DELTL 281_ EVGDI 286_ VSVID 291_ MPPKV 296_ LSTWW 301_ RGKHG 306_ FQVGL 311_ FPGHC 316_ VELIN 321_ QKVPQ 326_ SVTNS 331_ VPKPV 336_ SKKHG 341_ KLITF 346_ LRTFM 351_ KSRPT 356_ KQKLK 361_ QRGIL 366_ KERVF 371_ GCDLG 376_ EHLLN 381_ SGFEV 386_ PQVLQ 391_ SCTAF 396_ IERYG 401_ IVDGI 406_ YRLSG 411_ VASNI 416_ QRLRH 421_ EFDSE 426_ HVPDL 431_ TKEPY 436_ VQDIH 441_ SVGSL 446_ CKLYF 451_ RELPN 456_ PLLTY 461_ QLYEK 466_ FSDAV 471_ SAATD 476_ EERLI 481_ KIHDV 486_ IQQLP 491_ PPHYR 496_ TLEFL 501_ MRHLS 506_ LLADY 511_ CSITN 516_ MHAKN 521_ LAIVW 526_ APNLL 531_ RSKQI 536_ ESACF 541_ SGTAA 546_ FMEVR 551_ IQSVV 556_ VEFIL 561_ NHVDV 566_ LFSGR 571_ ISMAM 576_ QEGAA 581_ SLSRP 586_ KSLLV 591_ SSPST 596_ KLLTL 601_ EEAQA 606_ RTQAQ 611_ VNSPI 616_ VTENK 621_ YIEVG 626_ EGPAA 631_ LQGKF 636_ HTIIE 641_ FPLER 646_ KRPQN 651_ KMKKS 656_ PVGSW 661_ RSFFN 666_ LGKSS 671_ SVSKR 676_ KLQRN 681_ ESEPS 686_ EMKAM 691_ ALKGG 696_ RAEGT 701_ LRSAK 706_ SEESL 711_ TSLHA 716_ VDGDS 721_ KLFRP 726_ RRPRS 731_ SSDAL 736_ SASFN 741_ GEMLG 746_ NRCNS 751_ YDNLP 756_ HDNES 761_ EEEGG 766_ LLHIP 771_ ALMSP 776_ HSAED 781_ VDLSP 786_ PDIGV 791_ ASLDF 796_ DPMSF 801_ QCSPP 806_ KAESE 811_ CLESG 816_ ASFLD 821_ SPGYS 826_ KDKPS 831_ ANKKD 836_ AETGS 841_ SQCQT 846_ PGSTA 851_ SSEPV 856_ SPLQE 861_ KLSPF 866_ FTLDL 871_ SPTED 876_ KSSKP 881_ SSFTE 886_ KVVYA 891_ FSPKI 896_ GRKLS 901_ KSPSM 906_ SISEP 911_ ISVTL 916_ PPRVS 921_ EVIGT 926_ VSNTT 931_ AQNAS 936_ SSTWD 941_ KCVEE 946_ RDATN 951_ RSPTQ 956_ IVKMK 961_ TNETV 966_ AQEAY 971_ ESEVQ 976_ PLDQV 981_ AAEEV 986_ ELPGK 991_ EDQSV 996_ SSSQS 1001_ KAVAS 1006_ GQTQT 1011_ GAVTH 1016_ DPPQD 1021_ SVPVS 1026_ SVSLI 1031_ PPPPP 1036_ PKNVA 1041_ RMLAL 1046_ ALAES 1051_ AQQAS 1056_ TQSLK 1061_ RPGTS 1066_ QAGYT 1071_ NYGDI 1076_ AVATT 1081_ EDNLS 1086_ SSYSA 1091_ VALDK 1096_ AYFQT 1101_ DRPAE 1106_ QFHLQ 1111_ NNAPG 1116_ NCDHP 1121_ LPETT 1126_ ATGDP 1131_ THSNT 1136_ TESGE 1141_ QHHQV 1146_ DLTGN 1151_ QPHQA 1156_ YLSGD 1161_ PEKAR 1166_ ITSVP 1171_ LDSEK 1176_ SDDHV 1181_ SFPED 1186_ QSGKN 1191_ SMPTV 1196_ SFLDQ 1201_ DQSPP 1206_ RFYSG 1211_ DQPPS 1216_ YLGAS 1221_ VDKLH 1226_ HPLEF 1231_ ADKSP 1236_ TPPNL 1241_ PSDKI 1246_ YPPSG 1251_ SPEEN 1256_ TSTAT 1261_ MTYMT 1266_ TTPAT 1271_ AQMST 1276_ KEASW 1281_ DVAEQ 1286_ PTTAD 1291_ FAAAT 1296_ LQRTH 1301_ RTNRP 1306_ LPPPP 1311_ SQRSA 1316_ EQPPV 1321_ VGQVQ 1326_ AATNI 1331_ GLNNS 1336_ HKVQG 1341_ VVPVP 1346_ ERPPE 1351_ PRAMD 1356_ DPASA 1361_ FISDS 1366_ GAAAA 1371_ QCPMA 1376_ TAVQP 1381_ GLPEK 1386_ VRDGA 1391_ RVPLL 1396_ HLRAE 1401_ SVPAH 1406_ PCGFP 1411_ APLPP 1416_ TRMME 1421_ SKMIA 1426_ AIHSS 1431_ SADAT 1436_ SSSNY 1441_ HSFVT 1446_ ASSTS 1451_ VDDAL 1456_ PLPLP 1461_ VPQPK 1466_ HASQK 1471_ TVYSS 1476_ FARPD 1481_ VTTEP 1486_ FGPDN 1491_ CLHFN 1496_ MTPNC 1501_ QYRPQ 1506_ SVPPH 1511_ HNKLE 1516_ QHQVY 1521_ GARSE 1526_ PPASM 1531_ GLRYN 1536_ TYVAP 1541_ GRNAS 1546_ GHHSK 1551_ PCSRV 1556_ EYVSS 1561_ LSSSV 1566_ RNTCY 1571_ PEDIP 1576_ PYPTI 1581_ RRVQS 1586_ LHAPP 1591_ SSMIR 1596_ SVPIS 1601_ RTEVP 1606_ PDDEP 1611_ AYCPR 1616_ PLYQY 1621_ KPYQS 1626_ SQARS 1631_ DYHVT 1636_ QLQPY 1641_ FENGR 1646_ VHYRY 1651_ SPYSS 1656_ SSSSY 1661_ YSPDG 1666_ ALCDV 1671_ DAYGT 1676_ VQLRP 1681_ LHRLP 1686_ NRDFA 1691_ FYNPR 1696_ LQGKS 1701_ LYSYA 1706_ GLAPR 1711_ PRANV 1716_ TGYFS 1721_ PNDHN 1726_ VVSMP 1731_ PAADV 1736_ KHTYT 1741_ SWDLE 1746_ DMEKY 1751_ RMQSI 1756_ RRESR 1761_ ARQKV 1766_ KGPVM 1771_ SQYDN 1776_ MTPAV 1781_ QDDLG 1786_ GIYVI 1791_ HLRSK 1796_ SDPGK 1801_ TGLLS 1806_ VAEGK 1811_ ESRHA 1816_ AKAIS 1821_ PEGED 1826_ RFYRR 1831_ HPEAE 1836_ MDRAH 1841_ HHGGH 1846_ GSTQP 1851_ EKPSL 1856_ PQKQS 1861_ SLRSR 1866_ KLPDM 1871_ GCSLP 1876_ EHRAH 1881_ QEASH 1886_ RQFCE 1891_ SKNGP 1896_ PYPQG 1901_ AGQLD 1906_ YGSKG 1911_ IPDTS 1916_ EPVSY 1921_ HNSGV 1926_ KYAAS 1931_ GQESL 1936_ RLNHK 1941_ EVRLS 1946_ KEMER 1951_ PWVRQ 1956_ PSAPE 1961_ KHSRD 1966_ CYKEE 1971_ EHLTQ 1976_ SIVPP 1981_ PKPER 1986_ SHSLK 1991_ LHHTQ 1996_ NVERD 2001_ PSVLY 2006_ QYQPH 2011_ GKRQS 2016_ SVTVV 2021_ SQYDN 2026_ LEDYH 2031_ SLPQH 2036_ QRGVF 2041_ GGGGM 2046_ GTYVP 2051_ PGFPH 2056_ PQSRT 2061_ YATAL 2066_ GQGAF 2071_ LPAEL 2076_ SLQHP 2081_ETQIH
1: GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity)