Gamma-aminobutyric acid receptor subunit rho-3 (GABA(A) receptor subunit rho-3) (GABA(C) receptor)
1_MVLAF 6_ QLVSF 11_ TYIWI 16_ ILKPN 21_ VCAAS 26_ NIKMT 31_ HQRCS 36_ SSMKQ 41_ TCKQE 46_ TRMKK 51_ DDSTK 56_ ARPQK 61_ YEQLL 66_ HIEDN 71_ DFAMR 76_ PGFGG 81_ SPVPV 86_ GIDVH 91_ VESID 96_ SISET 101_ NMDFT 106_ MTFYL 111_ RHYWK 116_ DERLS 121_ FPSTA 126_ NKSMT 131_ FDHRL 136_ TRKIW 141_ VPDIF 146_ FVHSK 151_ RSFIH 156_ DTTME 161_ NIMLR 166_ VHPDG 171_ NVLLS 176_ LRITV 181_ SAMCF 186_ MDFSR 191_ FPLDT 196_ QNCSL 201_ ELESY 206_ AYNED 211_ DLMLY 216_ WKHGN 221_ KSLNT 226_ EEHMS 231_ LSQFF 236_ IEDFS 241_ ASSGL 246_ AFYSS 251_ TGWYN 256_ RLFIN 261_ FVLRR 266_ HVFFF 271_ VLQTY 276_ FPAIL 281_ MVMLS 286_ WVSFW 291_ IDRRA 296_ VPARV 301_ SLGIT 306_ TVLTM 311_ STIIT 316_ AVSAS 321_ MPQVS 326_ YLKAV 331_ DVYLW 336_ VSSLF 341_ VFLSV 346_ IEYAA 351_ VNYLT 356_ TVEER 361_ KQFKK 366_ TGKIS 371_ RMYNI 376_ DAVQA 381_ MAFDG 386_ CYHDS 391_ EIDMD 396_ QTSLS 401_ LNSED 406_ FMRRK 411_ SICSP 416_ STDSS 421_ RIKRR 426_ KSLGG 431_ HVGRI 436_ ILENN 441_ HVIDT 446_ YSRIL 451_ FPIVY 456_ ILFNL 461_FYWGV
1: Rho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (By similarity). Rho-containing GABA-gated chloride channels are a subclass of GABA(A) receptors (GABAARs) entirely composed of rho subunits, where GABA molecules bind at the rho intersubunit interfaces (By similarity). When activated by GABA, rho-GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient (By similarity)