Forkhead box protein I3
1_MALYC 6_ GDNFG 11_ VYSQP 16_ GLPPP 21_ AATAA 26_ APGAP 31_ PAARA 36_ PYGLA 41_ DYAAP 46_ PAAAA 51_ NPYLW 56_ LNGPG 61_ VGGPP 66_ SAAAA 71_ AAAAY 76_ LGAPP 81_ PPPPP 86_ GAAAG 91_ PFLQP 96_ PPAAG 101_ TFGCS 106_ QRPFA 111_ QPAPA 116_ APASP 121_ AAPAG 126_ PGELG 131_ WLSMA 136_ SREDL 141_ MKMVR 146_ PPYSY 151_ SALIA 156_ MAIQS 161_ APERK 166_ LTLSH 171_ IYQFV 176_ ADSFP 181_ FYQRS 186_ KAGWQ 191_ NSIRH 196_ NLSLN 201_ DCFKK 206_ VPRDE 211_ DDPGK 216_ GNYWT 221_ LDPNC 226_ EKMFD 231_ NGNFR 236_ RKRKR 241_ RSEAS 246_ NGSTV 251_ AAGTS 256_ KSEEG 261_ LSSGL 266_ GSGVG 271_ GKPEE 276_ ESPST 281_ LLRPS 286_ HSPEP 291_ PEGTK 296_ STASS 301_ PGGPM 306_ LTSTP 311_ CLNTF 316_ FSSLS 321_ SLSVS 326_ SSVST 331_ QRALP 336_ GSRHL 341_ GIQGA 346_ QLPSS 351_ GVFSP 356_ TSISE 361_ ASADT 366_ LQLSN 371_ STSNS 376_ TGQRS 381_ SYYSP 386_ FPAST 391_ SGGQS 396_ SPFSS 401_ PFHNF 406_ SMVNS 411_LIYPR
1: Transcription factor required for pharyngeal arch development, which is involved in hair, ear, jaw and dental development (PubMed:37041148). May act as a pioneer transcription factor during pharyngeal arch development (By similarity). Required for epithelial cell differentiation within the epidermis (By similarity). Acts at multiple stages of otic placode induction: necessary for preplacodal ectoderm to execute an inner ear program (By similarity). Required for hair follicle stem cell specification (By similarity). Acts downstream of TBX1 for the formation of the thymus and parathyroid glands from the third pharyngeal pouch (By similarity)