Gene name: CSKMT

Uniprot entry:

A8MUP2

Protein names:

Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT) (EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial)

Protein sequence:

1_MAALR 6_ RMLHL 11_ PSLMM 16_ GTCRP 21_ FAGSL 26_ ADSCL 31_ ADRCL 36_ WDRLH 41_ AQPRL 46_ GTVPT 51_ FDWFF 56_ GYDEV 61_ QGLLL 66_ PLLQE 71_ AQAAS 76_ PLRVL 81_ DVGCG 86_ TSSLC 91_ TGLYT 96_ KSPHP 101_ VDVLG 106_ VDFSP 111_ VAVAH 116_ MNSLL 121_ EGGPG 126_ QTPLC 131_ PGHPA 136_ SSLHF 141_ MHADA 146_ QNLGA 151_ VASSG 156_ SFQLL 161_ LDKGT 166_ WDAVA 171_ RGGLP 176_ RAYQL 181_ LSECL 186_ RVLNP 191_ QGTLI 196_ QFSDE 201_ DPDVR 206_ LPCLE 211_ QGSYG 216_ WTVTV 221_ QELGP 226_ FRGIT 231_YFAYL

Protein annotations

Protein functions:

1: Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria (PubMed:28391595, PubMed:28887308). Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methyl group per binding event (PubMed:28887308)