Gene name: FBXW7-AS1

Uniprot entry:

B0L3A2

Protein names:

Dual endothelin-1/angiotensin II receptor (Dear) (Dual endothelin-1/VEGFsp receptor) (DEspR protein) (FBXW7 antisense RNA 1)

Protein sequence:

1_MTMFK 6_ GSNEM 11_ KSRWN 16_ WGSIT 21_ CIICF 26_ TCVGS 31_ QLSMS 36_ SSKAS 41_ NFSGP 46_ LQLYQ 51_ RELEI 56_ FIVLT 61_ DVPNY 66_ RLIKE 71_ NSHLH 76_TTIVD

Protein annotations

Protein functions:

1: Dual receptor for both endothelin-1 and the signal sequence of vascular endothelial growth factor A (PubMed:17446437, PubMed:24465725). Does not act as a receptor for angiotensin-2 (PubMed:17446437). Does not bind the VEGFA mature protein (By similarity). May play a role in angiogenesis with a significant role in cardiovascular and neural development (By similarity)