T-cell-interacting, activating receptor on myeloid cells protein 1 (OSCAR-like transcript-2 protein) (OLT-2)
1_MIPKL 6_ LSLLC 11_ FRLCV 16_ GQGDT 21_ RGDGS 26_ LPKPS 31_ LSAWP 36_ SSVVP 41_ ANSNV 46_ TLRCW 51_ TPARG 56_ VSFVL 61_ RKGGI 66_ ILESP 71_ KPLDS 76_ TEGAA 81_ EFHLN 86_ NLKVR 91_ NAGEY 96_ TCEYY 101_ RKASP 106_ HILSQ 111_ RSDVL 116_ LLLVT 121_ GHLSK 126_ PFLRT 131_ YQRGT 136_ VTAGG 141_ RVTLQ 146_ CQKRD 151_ QLFVP 156_ IMFAL 161_ LKAGT 166_ PSPIQ 171_ LQSPA 176_ GKEID 181_ FSLVD 186_ VTAGD 191_ AGNYS 196_ CMYYQ 201_ TKSPF 206_ WASEP 211_ SDQLE 216_ ILVTV 221_ PPGTT 226_ SSNYS 231_ LGNFV 236_ RLGLA 241_ AVIVV 246_ IMGAF 251_ LVEAW 256_ YSRNV 261_ SPGES 266_EAFKP
1: May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901). Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity)