Gene name: SCRIB

Uniprot entry:

C0HLS1

Protein names:

SCRIB overlapping open reading frame protein (oSCRIB)

Protein sequence:

1_MRTEP 6_ RPPAP 11_ SPPSA 16_ AAGAR 21_ AAHPH 26_ HAQVH 31_ PAVAL 36_ QPARG 41_ VGGQA 46_ ALFAA 51_ GRAGG 56_ DLPLQ 61_ PQPGG 66_ AAARR 71_ QPAAR 76_ AAQAF 81_ FPAAE 86_ LAQAG 91_ PERQR 96_ DPAVA 101_ SRGGQ 106_ LHAAG 111_GAGRV

Protein annotations

Protein functions:

1: Represses translation of the downstream SCRIB protein (PubMed:34535749). Translation of oSCRIB hinders SCRIB translation but does not completely abolish it, probably due to leaky scanning which allows the ribosome to bypass the weaker oSCRIB start codon and initiate translation at the stronger SCRIB start codon (PubMed:34535749)