Putative RNA-binding regulatory peptide (RBRP) (Septin 14 pseudogene 20)
1_MIQQE 6_ EIRKL 11_ EEEKK 16_ QLEGE 21_ IIDFY 26_ KMKAA 31_ SEALQ 36_ TQLST 41_ DTKKD 46_ KHPDP 51_ YEFLL 56_ LRKIK 61_ HPGFN 66_EELSP
1: Enhances binding of IGF2BP1 to N6-methyladenosine (m6A)-containing mRNAs, thereby contributing to increased mRNA stability (PubMed:32245947). Also increases the interaction of IGF2BP1 with RNA stabilizers ELAVL1/HUR, MATR3 and PABPC1, and increases the interaction of RNA stabilizers ELAVL1/HUR, MATR3 and PABPC1 with m6A-containing mRNAs (PubMed:32245947). Contributes to MYC stability by enhancing binding of IGF2BP1 to m6A-containing MYC mRNAs and increasing recruitment of RNA stabilizing proteins to m6A-containing MYC mRNAs (PubMed:32245947)