MIEF1 upstream open reading frame protein (Alternative MIEF1 protein) (AltMIEF1) (MIEF1 microprotein) (MIEF1-MP)
1_MAPWS 6_ REAVL 11_ SLYRA 16_ LLRQG 21_ RQLRY 26_ TDRDF 31_ YFASI 36_ RREFR 41_ KNQKL 46_ EDAEA 51_ RERQL 56_ EKGLV 61_FLNGK
1: Assembly factor involved in the biogenesis of the mitochondrial-specific ribosomes (mitoribosomes) (PubMed:28892042, PubMed:30215512, PubMed:31666358). Specifically associates with intermediates of the mitochondrial ribosome large subunit (mt-LSU) and is required for proper ribosome assembly, possibly preventing premature association of the large and small ribosomal subunits (PubMed:28892042, PubMed:30215512, PubMed:31666358). Thereby, indirectly regulates mitochondrial translation (PubMed:28892042, PubMed:30215512, PubMed:31666358). It is also required for complete assembly of the mitochondrial respiratory chain complex I (PubMed:31666358). May also function in DNM1L-mediated mitochondrial fission (PubMed:29083303)