Ras-related protein Rab-27B (EC 3.6.5.2) (C25KG)
1_MTDGD 6_ YDYLI 11_ KLLAL 16_ GDSGV 21_ GKTTF 26_ LYRYT 31_ DNKFN 36_ PKFIT 41_ TVGID 46_ FREKR 51_ VVYNA 56_ QGPNG 61_ SSGKA 66_ FKVHL 71_ QLWDT 76_ AGQER 81_ FRSLT 86_ TAFFR 91_ DAMGF 96_ LLMFD 101_ LTSQQ 106_ SFLNV 111_ RNWMS 116_ QLQAN 121_ AYCEN 126_ PDIVL 131_ IGNKA 136_ DLPDQ 141_ REVNE 146_ RQARE 151_ LADKY 156_ GIPYF 161_ ETSAA 166_ TGQNV 171_ EKAVE 176_ TLLDL 181_ IMKRM 186_ EQCVE 191_ KTQIP 196_ DTVNG 201_ GNSGN 206_ LDGEK 211_PPEKK
1: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381). Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604). May be involved in targeting uroplakins to urothelial apical membranes (By similarity)