AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)
1_MSSNS 6_ FPYNE 11_ QSGGG 16_ EATEL 21_ GQEAT 26_ STISP 31_ SGAFG 36_ LFSSD 41_ LKKNE 46_ DLKQM 51_ LESNK 56_ DSAKL 61_ DAMKR 66_ IVGMI 71_ AKGKN 76_ ASELF 81_ PAVVK 86_ NVASK 91_ NIEIK 96_ KLVYV 101_ YLVRY 106_ AEEQQ 111_ DLALL 116_ SISTF 121_ QRALK 126_ DPNQL 131_ IRASA 136_ LRVLS 141_ SIRVP 146_ IIVPI 151_ MMLAI 156_ KEASA 161_ DLSPY 166_ VRKNA 171_ AHAIQ 176_ KLYSL 181_ DPEQK 186_ EMLIE 191_ VIEKL 196_ LKDKS 201_ TLVAG 206_ SVVMA 211_ FEEVC 216_ PDRID 221_ LIHKN 226_ YRKLC 231_ NLLVD 236_ VEEWG 241_ QVVII 246_ HMLTR 251_ YARTQ 256_ FVSPW 261_ KEGDE 266_ LEDNG 271_ KNFYE 276_ SDDDQ 281_ KEKTD 286_ KKKKP 291_ YTMDP 296_ DHRLL 301_ IRNTK 306_ PLLQS 311_ RNAAV 316_ VMAVA 321_ QLYWH 326_ ISPKS 331_ EAGII 336_ SKSLV 341_ RLLRS 346_ NREVQ 351_ YIVLQ 356_ NIATM 361_ SIQRK 366_ GMFEP 371_ YLKSF 376_ YVRST 381_ DPTMI 386_ KTLKL 391_ EILTN 396_ LANEA 401_ NISTL 406_ LREFQ 411_ TYVKS 416_ QDKQF 421_ AAATI 426_ QTIGR 431_ CATNI 436_ LEVTD 441_ TCLNG 446_ LVCLL 451_ SNRDE 456_ IVVAE 461_ SVVVI 466_ KKLLQ 471_ MQPAQ 476_ HGEII 481_ KHMAK 486_ LLDSI 491_ TVPVA 496_ RASIL 501_ WLIGE 506_ NCERV 511_ PKIAP 516_ DVLRK 521_ MAKSF 526_ TSEDD 531_ LVKLQ 536_ ILNLG 541_ AKLYL 546_ TNSKQ 551_ TKLLT 556_ QYILN 561_ LGKYD 566_ QNYDI 571_ RDRTR 576_ FIRQL 581_ IVPNV 586_ KSGAL 591_ SKYAK 596_ KIFLA 601_ QKPAP 606_ LLESP 611_ FKDRD 616_ HFQLG 621_ TLSHT 626_ LNIKA 631_ TGYLE 636_ LSNWP 641_ EVAPD 646_ PSVRN 651_ VEVIE 656_ LAKEW 661_ TPAGK 666_ AKQEN 671_ SAKKF 676_ YSESE 681_ EEEDS 686_ SDSSS 691_ DSESE 696_ SGSES 701_ GEQGE 706_ SGEEG 711_ DSNED 716_ SSEDS 721_ SSEQD 726_ SESGR 731_ ESGLE 736_ NKRTA 741_ KRNSK 746_ AKGKS 751_ DSEDG 756_ EKENE 761_ KSKTS 766_ DSSND 771_ ESSSI 776_ EDSSS 781_ DSESE 786_ SEPES 791_ ESESR 796_ RVTKE 801_ KEKKT 806_ KQDRT 811_ PLTKD 816_ VSLLD 821_ LDDFN 826_ PVSTP 831_ VALPT 836_ PALSP 841_ SLMAD 846_ LEGLH 851_ LSTSS 856_ SVISV 861_ STPAF 866_ VPTKT 871_ HVLLH 876_ RMSGK 881_ GLAAH 886_ YFFPR 891_ QPCIF 896_ GDKMV 901_ SIQIT 906_ LNNTT 911_ DRKIE 916_ NIHIG 921_ EKKLP 926_ IGMKM 931_ HVFNP 936_ IDSLE 941_ PEGSI 946_ TVSMG 951_ IDFCD 956_ STQTA 961_ SFQLC 966_ TKDDC 971_ FNVNI 976_ QPPVG 981_ ELLLP 986_ VAMSE 991_ KDFKK 996_ EQGVL 1001_ TGMNE 1006_ TSAVI 1011_ IAAPQ 1016_ NFTPS 1021_ VIFQK 1026_ VVNVA 1031_ NVGAV 1036_ PSGQD 1041_ NIHRF 1046_ AAKTV 1051_ HSGSL 1056_ MLVTV 1061_ ELKEG 1066_ STAQL 1071_ IINTE 1076_ KTVIG 1081_ SVLLR 1086_ELKPV
1: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals