Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1)
1_MTAAQ 6_ AAGEE 11_ APPGV 16_ RSVKV 21_ VLVGD 26_ GGCGK 31_ TSLLM 36_ VFADG 41_ AFPES 46_ YTPTV 51_ FERYM 56_ VNLQV 61_ KGKPV 66_ HLHIW 71_ DTAGQ 76_ DDYDR 81_ LRPLF 86_ YPDAS 91_ VLLLC 96_ FDVTS 101_ PNSFD 106_ NIFNR 111_ WYPEV 116_ NHFCK 121_ KVPII 126_ VVGCK 131_ TDLRK 136_ DKSLV 141_ NKLRR 146_ NGLEP 151_ VTYHR 156_ GQEMA 161_ RSVGA 166_ VAYLE 171_ CSARL 176_ HDNVH 181_ AVFQE 186_ AAEVA 191_ LSSRG 196_ RNFWR 201_RITQG
1: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution